30608:LOC105879235
gene id: 30608:LOC105879235
uniprot id: A0A8B7HD63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ECI1
gene id: 30608:ECI1
uniprot id: A0A8C5VPM1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

30608:PLD1
gene id: 30608:PLD1
uniprot id: A0A8B7EBZ3
uniprot id: A0A8B7ECB6
uniprot id: A0A8B7ECJ9
uniprot id: A0A8B7EEK3
names: Similarity
messages: Belongs to the phospholipase D family.

30608:PEMT
gene id: 30608:PEMT
uniprot id: A0A8B7F6F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

30608:MTMR1
gene id: 30608:MTMR1
uniprot id: A0A8B7FJK8
uniprot id: A0A8B7FJL3
uniprot id: A0A8B7FJL5
uniprot id: A0A8B7FJP1
uniprot id: A0A8B7FJP4
uniprot id: A0A8B7FJT3
uniprot id: A0A8B7FJT7
uniprot id: A0A8B7FJU3
uniprot id: A0A8B7FL07
uniprot id: A0A8B7WZA2
uniprot id: A0A8B7X119
uniprot id: A0A8C5XHP8
uniprot id: A0A8C5Y535
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

30608:LOC105879846
gene id: 30608:LOC105879846
uniprot id: A0A8B7HIA4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PSMC5
gene id: 30608:PSMC5
uniprot id: A0A8B7F4V3
uniprot id: A0A8B7F4W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

30608:PMPCB
gene id: 30608:PMPCB
uniprot id: A0A8B7F4H3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family.
messages: Heterodimer of PMPCA (alpha) and PMPCB (beta) subunits, forming the mitochondrial processing protease (MPP) in which PMPCA is involved in substrate recognition and binding and PMPCB is the catalytic subunit.
messages: Mitochondrion matrix

30608:TMEM98
gene id: 30608:TMEM98
uniprot id: A0A8C5UZ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM98 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: extracellular exosome

30608:ST6GALNAC5
gene id: 30608:ST6GALNAC5
uniprot id: A0A8B7I1A4
uniprot id: A0A8B7X0U6
uniprot id: A0A8C5Y8D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

30608:LOC105868329
gene id: 30608:LOC105868329
uniprot id: A0A8B7FYF8
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:MAPK1IP1L
gene id: 30608:MAPK1IP1L
uniprot id: A0A8B7FVW7
names: Similarity
messages: Belongs to the MISS family.

30608:RFC5
gene id: 30608:RFC5
uniprot id: A0A8B7FSB6
names: Similarity
messages: Belongs to the activator 1 small subunits family.

30608:SLITRK2
gene id: 30608:SLITRK2
uniprot id: A0A8B7HK81
names: Similarity
messages: Belongs to the SLITRK family.

30608:PFKM
gene id: 30608:PFKM
uniprot id: A0A8B7X5P6
uniprot id: A0A8B7X6B2
uniprot id: A0A8B7X6B6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:NUMB
gene id: 30608:NUMB
uniprot id: A0A8B7EP43
uniprot id: A0A8B7EP63
uniprot id: A0A8B7EP81
uniprot id: A0A8B7EQQ6
uniprot id: A0A8C5W3U9
uniprot id: A0A8C5Y4W4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Plays a role in the process of neurogenesis.

30608:LOC105864574
gene id: 30608:LOC105864574
uniprot id: A0A8B7FHP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:HAGH
gene id: 30608:HAGH
uniprot id: A0A8B7EUT4
uniprot id: A0A8B7EUT8
uniprot id: A0A8C5UM52
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

30608:CDH24
gene id: 30608:CDH24
uniprot id: A0A8B7FIF0
uniprot id: A0A8B7FJL9
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

30608:TBK1
gene id: 30608:TBK1
uniprot id: A0A8B7HK55
uniprot id: A0A8B7HK56
names: Subcellular Location Annotation
messages: Cytoplasm

30608:SLC16A7
gene id: 30608:SLC16A7
uniprot id: A0A8B7HAE7
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cytoplasm
messages: Membrane

30608:DNM1
gene id: 30608:DNM1
uniprot id: A0A8B7GVL5
uniprot id: A0A8B7GVM1
uniprot id: A0A8B7GVM2
uniprot id: A0A8B7GVS2
uniprot id: A0A8B7GXE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: cytoskeleton

30608:YAF2
gene id: 30608:YAF2
uniprot id: A0A8B7F1N8
uniprot id: A0A8B7F1S3
uniprot id: A0A8B7F1Y9
names: Subcellular Location Annotation
messages: Nucleus

30608:CENPL
gene id: 30608:CENPL
uniprot id: A0A8B7GDL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-L/IML3 family.
messages: Nucleus

30608:PHOSPHO2
gene id: 30608:PHOSPHO2
uniprot id: A0A8B7HJ23
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

30608:FAM3C
gene id: 30608:FAM3C
uniprot id: A0A8B7XD10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

30608:LIPJ
gene id: 30608:LIPJ
uniprot id: A0A8B7WM29
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

30608:LOC105864302
gene id: 30608:LOC105864302
uniprot id: A0A8B7FGJ3
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

30608:MZT1
gene id: 30608:MZT1
uniprot id: A0A8B7XE71
names: Function
names: Similarity
messages: Belongs to the MOZART1 family.
messages: Required for gamma-tubulin complex recruitment to the centrosome.

30608:CELF2
gene id: 30608:CELF2
uniprot id: A0A8B7ELS5
uniprot id: A0A8B7ELT0
uniprot id: A0A8B7EM14
uniprot id: A0A8B7EM19
uniprot id: A0A8B7EM23
uniprot id: A0A8B7EN57
uniprot id: A0A8B7EN62
uniprot id: A0A8B7EP11
uniprot id: A0A8B7EP16
uniprot id: A0A8B7EP21
uniprot id: A0A8B7WWD0
uniprot id: A0A8B7WWN8
uniprot id: A0A8B7WX44
uniprot id: A0A8B7WY30
uniprot id: A0A8B7WY41
uniprot id: A0A8C5Y7Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

30608:MAP1LC3B
gene id: 30608:MAP1LC3B
uniprot id: A0A8C5Y711
names: Similarity
messages: Belongs to the ATG8 family.

30608:LOC105861509
gene id: 30608:LOC105861509
uniprot id: A0A8B7FWW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

30608:ARRB1
gene id: 30608:ARRB1
uniprot id: A0A8B7EYK5
uniprot id: A0A8B7EYK8
uniprot id: A0A8B7EYK9
uniprot id: A0A8B7F0D2
uniprot id: A0A8B7F0P7
names: Similarity
messages: Belongs to the arrestin family.

30608:MB
gene id: 30608:MB
uniprot id: A0A8C5V5K1
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

30608:ACAD8
gene id: 30608:ACAD8
uniprot id: A0A8B7EK32
uniprot id: A0A8B7ELC0
uniprot id: A0A8B7EMF7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

30608:MRPS21
gene id: 30608:MRPS21
uniprot id: A0A8C5V9L5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

30608:ALKBH1
gene id: 30608:ALKBH1
uniprot id: A0A8C5W576
names: Similarity
messages: Belongs to the alkB family.

30608:HTR3B
gene id: 30608:HTR3B
uniprot id: A0A8B7FS05
names: Subcellular Location Annotation
messages: Membrane

30608:LSM6
gene id: 30608:LSM6
uniprot id: A0A8B7HNC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

30608:CMTM6
gene id: 30608:CMTM6
uniprot id: A0A8C5YHK7
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105870761
gene id: 30608:LOC105870761
uniprot id: A0A8B7WRQ7
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105874278
gene id: 30608:LOC105874278
uniprot id: A0A8B7GQK3
names: Similarity
messages: Belongs to the histone H2B family.

30608:PSMA2
gene id: 30608:PSMA2
uniprot id: A0A8B7ENB7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

30608:LOC105869359
gene id: 30608:LOC105869359
uniprot id: A0A8B7WWI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:PGLS
gene id: 30608:PGLS
uniprot id: A0A8C5XNG4
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

30608:LOC105869878
gene id: 30608:LOC105869878
uniprot id: A0A8B7G5E3
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

30608:WDR18
gene id: 30608:WDR18
uniprot id: A0A8B7F0G1
uniprot id: A0A8B7F257
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Component of the 5FMC complex, at least composed of PELP1, LAS1L, TEX10, WDR18 and SENP3; the complex interacts with methylated CHTOP and ZNF148. Interacts with NOL9. Component of the PELP1 complex, composed of at least PELP1, TEX10 and WDR18. The complex interacts with pre-60S ribosome particles.
messages: Cytoplasm
messages: Dynein axonemal particle
messages: Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit. May play a role during development.
messages: nucleolus
messages: nucleoplasm

30608:TLE2
gene id: 30608:TLE2
uniprot id: A0A8B7GNV8
uniprot id: A0A8B7GP60
uniprot id: A0A8B7GQB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

30608:PTGIS
gene id: 30608:PTGIS
uniprot id: A0A8C5XF64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2).
messages: Endoplasmic reticulum membrane

30608:DOCK8
gene id: 30608:DOCK8
uniprot id: A0A8B7XAS0
uniprot id: A0A8B7XCG6
uniprot id: A0A8C5UUD3
names: Similarity
messages: Belongs to the DOCK family.

30608:RPL22L1
gene id: 30608:RPL22L1
uniprot id: A0A8C6ELM1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

30608:CASKIN2
gene id: 30608:CASKIN2
uniprot id: A0A8B7HBS7
uniprot id: A0A8B7HEF3
uniprot id: A0A8C5UTJ6
names: Subcellular Location Annotation
messages: Cytoplasm

30608:TAF6L
gene id: 30608:TAF6L
uniprot id: A0A8B7HAB4
uniprot id: A0A8B7HD23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

30608:GRM8
gene id: 30608:GRM8
uniprot id: A0A8B7I1M9
uniprot id: A0A8B7I1N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

30608:SAR1B
gene id: 30608:SAR1B
uniprot id: A0A8B7WRT6
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

30608:RXRG
gene id: 30608:RXRG
uniprot id: A0A8B7EZ92
uniprot id: A0A8C5VEP1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

30608:TAP2
gene id: 30608:TAP2
uniprot id: A0A8B7IAJ3
names: Similarity
messages: Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.

30608:FAM126B
gene id: 30608:FAM126B
uniprot id: A0A8B7EIL9
uniprot id: A0A8B7EIM4
uniprot id: A0A8B7EIM6
uniprot id: A0A8C5VE04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM126 family.
messages: Cell membrane
messages: Membrane
messages: cytosol

30608:SAXO2
gene id: 30608:SAXO2
uniprot id: A0A8C5XQG3
names: Similarity
messages: Belongs to the FAM154 family.

30608:SMPD1
gene id: 30608:SMPD1
uniprot id: A0A8B7HVA7
uniprot id: A0A8B7HXF2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Converts sphingomyelin to ceramide.
messages: Secreted

30608:GPR107
gene id: 30608:GPR107
uniprot id: A0A8B7GVZ8
uniprot id: A0A8B7GW47
uniprot id: A0A8B7GXS9
uniprot id: A0A8B7XBE9
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105856563
gene id: 30608:LOC105856563
uniprot id: A0A8C5W4B2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:CDC42EP1
gene id: 30608:CDC42EP1
uniprot id: A0A8C5VXK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

30608:ARSA
gene id: 30608:ARSA
uniprot id: A0A8B7I5K1
uniprot id: A0A8C5XMZ8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

30608:PSME3
gene id: 30608:PSME3
uniprot id: A0A8C5VVR8
uniprot id: A0A8C5XNQ9
names: Similarity
messages: Belongs to the PA28 family.

30608:ZSCAN21
gene id: 30608:ZSCAN21
uniprot id: A0A8B7FY69
names: Subcellular Location Annotation
messages: Nucleus

30608:EME1
gene id: 30608:EME1
uniprot id: A0A8B7I671
uniprot id: A0A8B7WNK0
names: Similarity
messages: Belongs to the EME1/MMS4 family.

30608:MMP13
gene id: 30608:MMP13
uniprot id: A0A8B7GRX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CCN2. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CCN2. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.
messages: Secreted

30608:LOC105859855
gene id: 30608:LOC105859855
uniprot id: A0A8B7EW22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

30608:LOC105881124
gene id: 30608:LOC105881124
uniprot id: A0A8B7XDF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

30608:DHRS7C
gene id: 30608:DHRS7C
uniprot id: A0A8B7G3H2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:TSPAN12
gene id: 30608:TSPAN12
uniprot id: A0A8B7FU91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

30608:SLC25A53
gene id: 30608:SLC25A53
uniprot id: A0A8B7HWX6
uniprot id: A0A8B7HWY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:LOC105865934
gene id: 30608:LOC105865934
uniprot id: A0A8B7FNT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105881943
gene id: 30608:LOC105881943
uniprot id: A0A8B7HQF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105861315
gene id: 30608:LOC105861315
uniprot id: A0A8B7F2N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105884138
gene id: 30608:LOC105884138
uniprot id: A0A8B7I0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MRPL49
gene id: 30608:MRPL49
uniprot id: A0A8B7X752
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

30608:LCA5
gene id: 30608:LCA5
uniprot id: A0A8C5YBS7
names: Similarity
messages: Belongs to the LCA5 family.

30608:LOC105869724
gene id: 30608:LOC105869724
uniprot id: A0A8B7G4U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105883361
gene id: 30608:LOC105883361
uniprot id: A0A8B7HUV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105862117
gene id: 30608:LOC105862117
uniprot id: A0A8B7F729
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:C15H10orf90
gene id: 30608:C15H10orf90
uniprot id: A0A8B7HHW1
uniprot id: A0A8B7WM83
names: Subcellular Location Annotation
messages: centrosome

30608:LOC105858532
gene id: 30608:LOC105858532
uniprot id: A0A8B7EQ46
uniprot id: A0A8B7EQ57
uniprot id: A0A8B7ES96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.

30608:GMPPB
gene id: 30608:GMPPB
uniprot id: A0A8C5UZ59
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

30608:FGF23
gene id: 30608:FGF23
uniprot id: A0A8B7HPE1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

30608:CAMK1G
gene id: 30608:CAMK1G
uniprot id: A0A8C5W606
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:GABRP
gene id: 30608:GABRP
uniprot id: A0A8B7FTG8
uniprot id: A0A8B7FUF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:ABI3
gene id: 30608:ABI3
uniprot id: A0A8B7I321
uniprot id: A0A8C5UWW9
names: Similarity
messages: Belongs to the ABI family.

30608:ALKAL1
gene id: 30608:ALKAL1
uniprot id: A0A8B7I3Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

30608:SF3A2
gene id: 30608:SF3A2
uniprot id: A0A8B7F036
names: Similarity
messages: Belongs to the SF3A2 family.

30608:PPIA
gene id: 30608:PPIA
uniprot id: A0A8B7G8U3
uniprot id: A0A8B7G9Y0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

30608:GRIN2D
gene id: 30608:GRIN2D
uniprot id: A0A8B7FNF8
uniprot id: A0A8C5VCH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

30608:MEIS1
gene id: 30608:MEIS1
uniprot id: A0A8C5VII1
uniprot id: A0A8C5W4K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

30608:ATP8B2
gene id: 30608:ATP8B2
uniprot id: A0A8B7I6R2
uniprot id: A0A8C5XXZ5
uniprot id: A0A8C6EI48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

30608:LOC105871768
gene id: 30608:LOC105871768
uniprot id: A0A8B7GDL4
names: Similarity
messages: Belongs to the SMIM12 family.

30608:LOC105883161
gene id: 30608:LOC105883161
uniprot id: A0A8B7HW76
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

30608:LOC105882826
gene id: 30608:LOC105882826
uniprot id: A0A8B7HSN0
names: Similarity
messages: Belongs to the SKP1 family.

30608:TRABD2A
gene id: 30608:TRABD2A
uniprot id: A0A8B7H351
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

30608:PRLR
gene id: 30608:PRLR
uniprot id: A0A8B7FW55
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Interacts with SMARCA1. Interacts with NEK3 and VAV2 and this interaction is prolactin-dependent.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

30608:LOC105872046
gene id: 30608:LOC105872046
uniprot id: A0A8C5W2F9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:C9H8orf33
gene id: 30608:C9H8orf33
uniprot id: A0A8B7G183
uniprot id: A0A8B7G2K8
names: Similarity
messages: Belongs to the UPF0488 family.

30608:NUDT18
gene id: 30608:NUDT18
uniprot id: A0A8B7EJ73
uniprot id: A0A8B7EJJ2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

30608:SERP1
gene id: 30608:SERP1
uniprot id: A0A8B7HL84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

30608:CLTA
gene id: 30608:CLTA
uniprot id: A0A8B7GQD7
uniprot id: A0A8B7GQN2
uniprot id: A0A8B7GQT1
uniprot id: A0A8B7GRY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

30608:PRCP
gene id: 30608:PRCP
uniprot id: A0A8B7EBK0
uniprot id: A0A8B7EBW3
names: Similarity
messages: Belongs to the peptidase S28 family.

30608:KCNQ4
gene id: 30608:KCNQ4
uniprot id: A0A8B7EAK5
uniprot id: A0A8B7ED85
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:PABPC1
gene id: 30608:PABPC1
uniprot id: A0A8B7X9V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

30608:LOC105859917
gene id: 30608:LOC105859917
uniprot id: A0A8B7EYA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CD68
gene id: 30608:CD68
uniprot id: A0A8C5V1Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

30608:LOC105881601
gene id: 30608:LOC105881601
uniprot id: A0A8B7HM91
names: Subcellular Location Annotation
messages: Membrane

30608:CNNM2
gene id: 30608:CNNM2
uniprot id: A0A8B7GRG5
uniprot id: A0A8B7GRH6
uniprot id: A0A8C5V1W2
uniprot id: A0A8C5VBP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

30608:EDNRA
gene id: 30608:EDNRA
uniprot id: A0A8C5VBP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

30608:DAZL
gene id: 30608:DAZL
uniprot id: A0A8B7GHW0
names: Subcellular Location Annotation
messages: Cytoplasm

30608:SEMA4B
gene id: 30608:SEMA4B
uniprot id: A0A8B7G8L6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:MED31
gene id: 30608:MED31
uniprot id: A0A8C5VIV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

30608:LOC105878054
gene id: 30608:LOC105878054
uniprot id: A0A8B7H800
names: Function
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH.

30608:EXOSC1
gene id: 30608:EXOSC1
uniprot id: A0A8B7GJS9
names: Subcellular Location Annotation
messages: Cytoplasm

30608:GSPT1
gene id: 30608:GSPT1
uniprot id: A0A8B7HSH7
uniprot id: A0A8C5V7W6
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

30608:SIX5
gene id: 30608:SIX5
uniprot id: A0A8C5XZ35
names: Subcellular Location Annotation
messages: Nucleus

30608:C5AR2
gene id: 30608:C5AR2
uniprot id: A0A8B7G4B4
names: Subcellular Location Annotation
messages: Cell membrane

30608:MLST8
gene id: 30608:MLST8
uniprot id: A0A8B7EUZ0
uniprot id: A0A8B7EWX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LST8 family.
messages: Cytoplasm
messages: Part of the mammalian target of rapamycin complex 1 (mTORC1) which contains MTOR, MLST8, RPTOR, AKT1S1/PRAS40 and DEPTOR. mTORC1 binds to and is inhibited by FKBP12-rapamycin. Part of the mammalian target of rapamycin complex 2 (mTORC2) which contains MTOR, MLST8, PRR5, RICTOR, MAPKAP1 and DEPTOR. Contrary to mTORC1, mTORC2 does not bind to and is not sensitive to FKBP12-rapamycin. Interacts directly with MTOR and RPTOR. Interacts with RHEB. Interacts with MEAK7. Interacts with SIK3.
messages: Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1, which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation. Within mTORC1, LST8 interacts directly with MTOR and enhances its kinase activity. In nutrient-poor conditions, stabilizes the MTOR-RPTOR interaction and favors RPTOR-mediated inhibition of MTOR activity. mTORC2 is also activated by growth factors, but seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1. mTORC2 also modulates the phosphorylation of PRKCA.

30608:ALDH1L2
gene id: 30608:ALDH1L2
uniprot id: A0A8C5VVH3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

30608:LOC105863924
gene id: 30608:LOC105863924
uniprot id: A0A8B7FG76
uniprot id: A0A8C5YA04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

30608:KIF22
gene id: 30608:KIF22
uniprot id: A0A8B7GBH8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:LOC105877375
gene id: 30608:LOC105877375
uniprot id: A0A8B7H4G4
uniprot id: A0A8B7H4G5
names: Similarity
names: Subunit
messages: Homodimer. Interacts with PKM.
messages: In the N-terminal section; belongs to the type II pantothenate kinase family.

30608:TNS2
gene id: 30608:TNS2
uniprot id: A0A8B7G8I3
uniprot id: A0A8B7G8R5
uniprot id: A0A8B7G9Q2
uniprot id: A0A8C5V159
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

30608:GSTO1
gene id: 30608:GSTO1
uniprot id: A0A8B7GS93
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

30608:POU6F2
gene id: 30608:POU6F2
uniprot id: A0A8B7H8S0
uniprot id: A0A8B7H8T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

30608:LSR
gene id: 30608:LSR
uniprot id: A0A8B7H2Q9
uniprot id: A0A8B7H2R0
uniprot id: A0A8B7H2R1
uniprot id: A0A8B7H4X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

30608:KCNK15
gene id: 30608:KCNK15
uniprot id: A0A8B7HGQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

30608:LOC105877512
gene id: 30608:LOC105877512
uniprot id: A0A8B7H577
uniprot id: A0A8B7H578
uniprot id: A0A8B7H7I9
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:STK32C
gene id: 30608:STK32C
uniprot id: A0A8B7HKK7
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:DNAJC24
gene id: 30608:DNAJC24
uniprot id: A0A8B7HVK6
uniprot id: A0A8B7HVS1
uniprot id: A0A8C5UXL3
names: Similarity
messages: Belongs to the DPH4 family.

30608:DOCK3
gene id: 30608:DOCK3
uniprot id: A0A8B7GTX9
uniprot id: A0A8B7GTY4
uniprot id: A0A8B7GU33
uniprot id: A0A8B7GU38
uniprot id: A0A8B7GU58
uniprot id: A0A8B7GVR3
uniprot id: A0A8B7GVR8
uniprot id: A0A8B7WL29
names: Similarity
messages: Belongs to the DOCK family.

30608:GNB5
gene id: 30608:GNB5
uniprot id: A0A8B7G8Z6
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

30608:EHD1
gene id: 30608:EHD1
uniprot id: A0A8B7HCK7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: cilium membrane

30608:HBP1
gene id: 30608:HBP1
uniprot id: A0A8B7F383
uniprot id: A0A8C5XDX3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

30608:TSPAN1
gene id: 30608:TSPAN1
uniprot id: A0A8C5UPS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

30608:TPRKB
gene id: 30608:TPRKB
uniprot id: A0A8C5XVR3
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

30608:CLIC3
gene id: 30608:CLIC3
uniprot id: A0A8B7HRY5
uniprot id: A0A8C5VUZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

30608:CHDH
gene id: 30608:CHDH
uniprot id: A0A8C5V6B6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

30608:MYOZ2
gene id: 30608:MYOZ2
uniprot id: A0A8B7HWV9
names: Similarity
messages: Belongs to the myozenin family.

30608:CALY
gene id: 30608:CALY
uniprot id: A0A8B7F449
names: Similarity
messages: Belongs to the NSG family.

30608:ASB14
gene id: 30608:ASB14
uniprot id: A0A8B7GEY4
uniprot id: A0A8B7GF78
uniprot id: A0A8B7WL70
uniprot id: A0A8C5USY6
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

30608:LOC105861366
gene id: 30608:LOC105861366
uniprot id: A0A8B7F2U5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

30608:STARD13
gene id: 30608:STARD13
uniprot id: A0A8B7XDW7
uniprot id: A0A8B7XG70
uniprot id: A0A8C5Y9A1
names: Subcellular Location Annotation
messages: Cytoplasm

30608:LOC105880747
gene id: 30608:LOC105880747
uniprot id: A0A8B7XDU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

30608:DPP7
gene id: 30608:DPP7
uniprot id: A0A8C5UTR0
names: Similarity
messages: Belongs to the peptidase S28 family.

30608:F3
gene id: 30608:F3
uniprot id: A0A8B7I9F5
uniprot id: A0A8C5UZG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.
messages: Membrane

30608:DLL3
gene id: 30608:DLL3
uniprot id: A0A8B7H3S1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:JMY
gene id: 30608:JMY
uniprot id: A0A8C5VLR2
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105866317
gene id: 30608:LOC105866317
uniprot id: A0A8B7FQ84
names: Similarity
messages: Belongs to the PPP4R2 family.

30608:ELF5
gene id: 30608:ELF5
uniprot id: A0A8B7FPY1
uniprot id: A0A8B7FQY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:IFITM10
gene id: 30608:IFITM10
uniprot id: A0A8B7EVY2
uniprot id: A0A8B7X4H7
names: Similarity
messages: Belongs to the CD225/Dispanin family.

30608:TMEM225
gene id: 30608:TMEM225
uniprot id: A0A8B7FQW4
uniprot id: A0A8B7FR10
uniprot id: A0A8B7FS03
names: Subcellular Location Annotation
messages: Membrane

30608:F2
gene id: 30608:F2
uniprot id: A0A8C5UT53
names: Caution
names: Function
names: Similarity
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

30608:NR5A1
gene id: 30608:NR5A1
uniprot id: A0A8B7GV83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

30608:TARBP2
gene id: 30608:TARBP2
uniprot id: A0A8B7GA26
uniprot id: A0A8B7GAD7
uniprot id: A0A8B7GB37
uniprot id: A0A8C5YAK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TARBP2 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
messages: Self-associates. Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC. Interacts with EIF2AK2/PKR and inhibits its protein kinase activity. Interacts with DHX9 and PRKRA. Interacts with DICER1, AGO2, MOV10, EIF6 and RPL7A (60S ribosome subunit); they form a large RNA-induced silencing complex (RISC).
messages: perinuclear region

30608:MAPK14
gene id: 30608:MAPK14
uniprot id: A0A8C5VDN4
uniprot id: A0A8C5YBE5
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

30608:LOC105874381
gene id: 30608:LOC105874381
uniprot id: A0A8C5Y9Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TAF5L
gene id: 30608:TAF5L
uniprot id: A0A8C5XQV8
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

30608:MTCL1
gene id: 30608:MTCL1
uniprot id: A0A8B7F196
uniprot id: A0A8B7F198
uniprot id: A0A8B7F302
names: Similarity
messages: Belongs to the SOGA family.

30608:PTPRJ
gene id: 30608:PTPRJ
uniprot id: A0A8B7X3G9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

30608:DAO
gene id: 30608:DAO
uniprot id: A0A8B7FSV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

30608:SIGMAR1
gene id: 30608:SIGMAR1
uniprot id: A0A8C5YI22
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERG2 family.
messages: Cell junction
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum membrane
messages: Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the endoplasmic reticulum.
messages: Homotrimer.
messages: Lipid droplet
messages: Membrane
messages: Nucleus envelope
messages: Nucleus inner membrane
messages: Nucleus outer membrane
messages: Postsynaptic density membrane
messages: The C-terminal helices form a flat, hydrophobic surface that is probably tightly associated with the cytosolic surface of the endoplasmic reticulum membrane.
messages: Vesicle

30608:THYN1
gene id: 30608:THYN1
uniprot id: A0A8B7EK36
uniprot id: A0A8B7EMG0
names: Function
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

30608:LOC105867204
gene id: 30608:LOC105867204
uniprot id: A0A8B7FTJ0
names: Similarity
messages: Belongs to the MS4A family.

30608:DUOX1
gene id: 30608:DUOX1
uniprot id: A0A8C5UZJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
messages: In the N-terminal section; belongs to the peroxidase family.
messages: Membrane

30608:CHAC1
gene id: 30608:CHAC1
uniprot id: A0A8B7GHA9
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

30608:DERL1
gene id: 30608:DERL1
uniprot id: A0A8B7EU68
uniprot id: A0A8B7EW57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:GPR137
gene id: 30608:GPR137
uniprot id: A0A8B7H9J6
uniprot id: A0A8B7H9L2
uniprot id: A0A8C5W9Y9
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

30608:SCG5
gene id: 30608:SCG5
uniprot id: A0A8B7GG93
uniprot id: A0A8B7GGA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
messages: Belongs to the 7B2 family.
messages: Interacts with PCSK2/PC2 early in the secretory pathway. Dissociation occurs at later stages.
messages: Secreted

30608:LOC105865205
gene id: 30608:LOC105865205
uniprot id: A0A8B7FKA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:RIDA
gene id: 30608:RIDA
uniprot id: A0A8B7G666
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.
messages: Peroxisome

30608:IGF2BP3
gene id: 30608:IGF2BP3
uniprot id: A0A8B7XBM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Nucleus
messages: P-body
messages: Stress granule

30608:SUCLG1
gene id: 30608:SUCLG1
uniprot id: A0A8B7H0V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.

30608:ATP11C
gene id: 30608:ATP11C
uniprot id: A0A8B7HKG0
uniprot id: A0A8B7HKG1
uniprot id: A0A8C5VIU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

30608:TPM3
gene id: 30608:TPM3
uniprot id: A0A8B7IA62
uniprot id: A0A8B7WZX1
uniprot id: A0A8B7WZX3
uniprot id: A0A8B7WZX8
uniprot id: A0A8B7WZY5
uniprot id: A0A8B7X0F9
uniprot id: A0A8B7X0G8
uniprot id: A0A8B7X0H4
uniprot id: A0A8B7X111
uniprot id: A0A8B7X121
uniprot id: A0A8B7X127
uniprot id: A0A8B7X1M3
uniprot id: A0A8B7X1M7
uniprot id: A0A8B7X1N3
uniprot id: A0A8C5XDA1
uniprot id: A0A8C5Y2Z6
uniprot id: A0A8C5YH16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

30608:RPS8
gene id: 30608:RPS8
uniprot id: A0A8B7H5T5
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs.

30608:SMAD9
gene id: 30608:SMAD9
uniprot id: A0A8B7F6V5
uniprot id: A0A8B7XF72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

30608:LOC105860863
gene id: 30608:LOC105860863
uniprot id: A0A8B7F324
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZC3H14 family.
messages: Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
messages: Nucleus speckle

30608:WDR24
gene id: 30608:WDR24
uniprot id: A0A8B7EG28
names: Similarity
messages: Belongs to the WD repeat WDR24 family.

30608:EDN2
gene id: 30608:EDN2
uniprot id: A0A8C6EIH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

30608:SDHAF1
gene id: 30608:SDHAF1
uniprot id: A0A8B7H4Q0
names: Similarity
messages: Belongs to the complex I LYR family. SDHAF1 subfamily.

30608:KRT18
gene id: 30608:KRT18
uniprot id: A0A8B7G8G2
names: Similarity
messages: Belongs to the intermediate filament family.

30608:BRCC3
gene id: 30608:BRCC3
uniprot id: A0A8B7WZT8
uniprot id: A0A8B7X109
uniprot id: A0A8C5Y4P9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M67A family. BRCC36 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Component of the BRCA1-A complex. Component of the BRISC complex. Both the BRCA1-A complex and the BRISC complex bind polyubiquitin.
messages: Cytoplasm
messages: Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the brca1-bard1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). Catalytic subunit of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex. The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1.
messages: Nucleus
messages: spindle pole

30608:KMO
gene id: 30608:KMO
uniprot id: A0A8C5Y977
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
messages: Mitochondrion outer membrane

30608:LOC105872443
gene id: 30608:LOC105872443
uniprot id: A0A8C5Y2I2
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:MMD2
gene id: 30608:MMD2
uniprot id: A0A8B7FZ31
uniprot id: A0A8C5W4M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

30608:LOC105864669
gene id: 30608:LOC105864669
uniprot id: A0A8B7FHX4
names: Subcellular Location Annotation
messages: Membrane

30608:GPC2
gene id: 30608:GPC2
uniprot id: A0A8B7G006
uniprot id: A0A8B7WNW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

30608:KIF3A
gene id: 30608:KIF3A
uniprot id: A0A8B7G5R9
uniprot id: A0A8B7G5S2
uniprot id: A0A8B7G5V7
uniprot id: A0A8B7G6I2
uniprot id: A0A8B7G718
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:PRDX1
gene id: 30608:PRDX1
uniprot id: A0A8C5V2H2
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

30608:NDRG4
gene id: 30608:NDRG4
uniprot id: A0A8B7EVS5
uniprot id: A0A8B7EVS7
uniprot id: A0A8B7EXQ4
uniprot id: A0A8B7EXR7
uniprot id: A0A8C5VY16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDRG family.
messages: cytosol

30608:BNIP1
gene id: 30608:BNIP1
uniprot id: A0A8B7GEW2
uniprot id: A0A8B7GF16
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105861322
gene id: 30608:LOC105861322
uniprot id: A0A8B7F2P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105883391
gene id: 30608:LOC105883391
uniprot id: A0A8B7HV03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PDC
gene id: 30608:PDC
uniprot id: A0A8B7EC65
names: Similarity
messages: Belongs to the phosducin family.

30608:LOC105884146
gene id: 30608:LOC105884146
uniprot id: A0A8B7HYK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC109729960
gene id: 30608:LOC109729960
uniprot id: A0A8B7WUV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

30608:NLGN3
gene id: 30608:NLGN3
uniprot id: A0A8B7EBV7
uniprot id: A0A8B7EC58
uniprot id: A0A8B7EE65
uniprot id: A0A8C5Y214
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

30608:MAN2C1
gene id: 30608:MAN2C1
uniprot id: A0A8B7E9K8
uniprot id: A0A8B7E9P3
uniprot id: A0A8B7ECE0
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

30608:PNKD
gene id: 30608:PNKD
uniprot id: A0A8B7EMX1
uniprot id: A0A8C5Y2F4
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

30608:COL4A5
gene id: 30608:COL4A5
uniprot id: A0A8B7FCI9
uniprot id: A0A8B7FCM1
uniprot id: A0A8B7FCM7
uniprot id: A0A8B7FD45
uniprot id: A0A8B7FD85
uniprot id: A0A8C5UTF8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

30608:CCDC167
gene id: 30608:CCDC167
uniprot id: A0A8B7F326
names: Subcellular Location Annotation
messages: Membrane

30608:SLC35B2
gene id: 30608:SLC35B2
uniprot id: A0A8B7EUD0
uniprot id: A0A8B7EUD6
uniprot id: A0A8B7EWC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

30608:FGA
gene id: 30608:FGA
uniprot id: A0A8C5UP64
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

30608:CELSR2
gene id: 30608:CELSR2
uniprot id: A0A8B7FGC7
uniprot id: A0A8C5Y5C7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

30608:GAP43
gene id: 30608:GAP43
uniprot id: A0A8B7HSR1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neuromodulin family.
messages: Cell membrane
messages: Cytoplasm
messages: Identified in a complex containing FGFR4, NCAM1, CDH2, PLCG1, FRS2, SRC, SHC1, GAP43 and CTTN. Interacts (via IQ domain) with calmodulin. Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.
messages: Membrane
messages: Palmitoylated. Palmitoylation is essential for plasma membrane association.
messages: Perikaryon
messages: Synapse
messages: This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
messages: axon
messages: dendrite
messages: filopodium membrane
messages: growth cone membrane

30608:FGF9
gene id: 30608:FGF9
uniprot id: A0A8C5W6A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heparin-binding growth factors family.
messages: Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.
messages: Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.
messages: Secreted

30608:LOC105874565
gene id: 30608:LOC105874565
uniprot id: A0A8B7GRT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

30608:LSM5
gene id: 30608:LSM5
uniprot id: A0A8B7ER96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

30608:AP3S1
gene id: 30608:AP3S1
uniprot id: A0A8B7G9J1
uniprot id: A0A8B7G9J3
uniprot id: A0A8B7GA61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

30608:NKIRAS1
gene id: 30608:NKIRAS1
uniprot id: A0A8B7EZA9
uniprot id: A0A8B7F1I4
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

30608:LOC109729822
gene id: 30608:LOC109729822
uniprot id: A0A8B7WT30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative pheromone receptor.

30608:DLX4
gene id: 30608:DLX4
uniprot id: A0A8B7I5Z8
names: Subcellular Location Annotation
messages: Nucleus

30608:TMEM70
gene id: 30608:TMEM70
uniprot id: A0A8B7EA56
names: Similarity
messages: Belongs to the TMEM70 family.

30608:MRPL16
gene id: 30608:MRPL16
uniprot id: A0A8B7G066
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

30608:C5H11orf88
gene id: 30608:C5H11orf88
uniprot id: A0A8B7FAD1
uniprot id: A0A8C5XQG9
names: Similarity
messages: Belongs to the HOATZ family.

30608:ZFHX2
gene id: 30608:ZFHX2
uniprot id: A0A8B7FIB9
uniprot id: A0A8B7FJH9
uniprot id: A0A8B7X2D6
names: Subcellular Location Annotation
messages: Nucleus

30608:UNC13C
gene id: 30608:UNC13C
uniprot id: A0A8B7HLU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-13 family.
messages: Cytoplasm
messages: Membrane

30608:PSMC2
gene id: 30608:PSMC2
uniprot id: A0A8C5XKR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
messages: Cytoplasm

30608:LOC105874627
gene id: 30608:LOC105874627
uniprot id: A0A8C5VAE2
names: Similarity
messages: Belongs to the HPF1 family.

30608:TRAM2
gene id: 30608:TRAM2
uniprot id: A0A8B7G2L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

30608:CUL3
gene id: 30608:CUL3
uniprot id: A0A8B7F9Y8
names: Similarity
messages: Belongs to the cullin family.

30608:PDYN
gene id: 30608:PDYN
uniprot id: A0A8C5XS88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin.
messages: Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Leumorphin has a typical opiod activity and may have anti-apoptotic effect.
messages: Secreted

30608:RNF141
gene id: 30608:RNF141
uniprot id: A0A8B7FQN4
names: Function
messages: May be involved in spermatogenesis.

30608:PELI2
gene id: 30608:PELI2
uniprot id: A0A8B7HSS5
uniprot id: A0A8B7HSU9
names: Similarity
messages: Belongs to the pellino family.

30608:MTNR1A
gene id: 30608:MTNR1A
uniprot id: A0A8B7HSY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
messages: Membrane

30608:LOC109730017
gene id: 30608:LOC109730017
uniprot id: A0A8B7WXS6
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

30608:REEP5
gene id: 30608:REEP5
uniprot id: A0A8B7G9N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

30608:LOC105877998
gene id: 30608:LOC105877998
uniprot id: A0A8B7H7R5
uniprot id: A0A8B7H7R6
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:BROX
gene id: 30608:BROX
uniprot id: A0A8B7ECP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BROX family.
messages: Membrane

30608:PNLIPRP2
gene id: 30608:PNLIPRP2
uniprot id: A0A8B7H3X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

30608:GPRC5B
gene id: 30608:GPRC5B
uniprot id: A0A8B7EB70
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:ERN1
gene id: 30608:ERN1
uniprot id: A0A8B7F5C1
uniprot id: A0A8B7F5D8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:MOV10
gene id: 30608:MOV10
uniprot id: A0A8B7HB05
uniprot id: A0A8B7HB08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

30608:GALNT12
gene id: 30608:GALNT12
uniprot id: A0A8B7GN08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

30608:FAM229B
gene id: 30608:FAM229B
uniprot id: A0A8B7X6N5
names: Similarity
messages: Belongs to the FAM229 family.

30608:TLL2
gene id: 30608:TLL2
uniprot id: A4PCE0
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ZSCAN25
gene id: 30608:ZSCAN25
uniprot id: A0A8B7FZE4
uniprot id: A0A8C5Y608
names: Subcellular Location Annotation
messages: Nucleus

30608:KCNU1
gene id: 30608:KCNU1
uniprot id: A0A8B7G7S6
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105864301
gene id: 30608:LOC105864301
uniprot id: A0A8C6EE86
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

30608:GLYR1
gene id: 30608:GLYR1
uniprot id: A0A8B7EV68
uniprot id: A0A8B7EX61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIBADH-related family. NP60 subfamily.
messages: Chromosome

30608:CDH8
gene id: 30608:CDH8
uniprot id: A0A8B7HKR4
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

30608:GAREM1
gene id: 30608:GAREM1
uniprot id: A0A8B7HKK0
uniprot id: A0A8B7HLS4
uniprot id: A0A8B7WRM4
names: Similarity
messages: Belongs to the GAREM family.

30608:PAQR9
gene id: 30608:PAQR9
uniprot id: A0A8B7G6H1
uniprot id: A0A8B7G7J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

30608:DYNLL1
gene id: 30608:DYNLL1
uniprot id: A0A8B7WTM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

30608:FBLN5
gene id: 30608:FBLN5
uniprot id: A0A8B7H032
uniprot id: A0A8B7X0H0
names: Caution
names: Similarity
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:COQ10A
gene id: 30608:COQ10A
uniprot id: A0A8B7FKN3
uniprot id: A0A8B7FKS2
uniprot id: A0A8B7FKV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

30608:LOC105869706
gene id: 30608:LOC105869706
uniprot id: A0A8B7G4T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105864743
gene id: 30608:LOC105864743
uniprot id: A0A8B7FJN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SLC22A24
gene id: 30608:SLC22A24
uniprot id: A0A8B7HA97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
messages: Cell membrane
messages: Renal transmembrane organic anion/dicarboxylate exchanger that participates in the reabsorption of conjugated steroids, as well as bile acids, driven by an outward gradient of dicarboxylates such as glutarate or succinate (By similarity). Transports androstanediol glucuronide (5alpha-androstane-3alpha,17beta-diol 3-O-(beta-D-glucuronate)), estrone 3-sulfate, and estradiol-17-glucuronide (17beta-estradiol 17-O-(beta-D-glucuronate)), but not taurocholate (PubMed:31553721).

30608:CSK
gene id: 30608:CSK
uniprot id: A0A8B7EAE7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

30608:LOC105883383
gene id: 30608:LOC105883383
uniprot id: A0A8B7HUY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LARS
gene id: 30608:LARS
uniprot id: A0A8C5V924
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

30608:LOC105880435
gene id: 30608:LOC105880435
uniprot id: A0A8B7HI23
names: Similarity
messages: Belongs to the semenogelin family.

30608:BEX2
gene id: 30608:BEX2
uniprot id: A0A8B7HYP8
names: Similarity
messages: Belongs to the BEX family.

30608:B4GALNT4
gene id: 30608:B4GALNT4
uniprot id: A0A8B7GPF7
uniprot id: A0A8B7GPG1
uniprot id: A0A8B7GPW4
uniprot id: A0A8B7GQY6
uniprot id: A0A8B7X2S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

30608:SNRPB
gene id: 30608:SNRPB
uniprot id: A0A8B7FNX0
uniprot id: A0A8B7FP65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

30608:GLRA2
gene id: 30608:GLRA2
uniprot id: A0A8B7HSQ0
uniprot id: A0A8B7HT82
uniprot id: A0A8C5Y7T7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

30608:DYNC2LI1
gene id: 30608:DYNC2LI1
uniprot id: A0A8C5XMV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light intermediate chain family.
messages: centrosome
messages: cilium
messages: cilium axoneme
messages: cilium basal body

30608:NR2F1
gene id: 30608:NR2F1
uniprot id: A0A8B7FFY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

30608:MYADML2
gene id: 30608:MYADML2
uniprot id: A0A8B7I4F1
names: Subcellular Location Annotation
messages: Membrane

30608:CENPO
gene id: 30608:CENPO
uniprot id: A0A8C5V798
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

30608:FAM26E
gene id: 30608:FAM26E
uniprot id: A0A8B7FJF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

30608:HPS6
gene id: 30608:HPS6
uniprot id: A0A8B7GPR4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6. Interacts with HPS5 and HPS3. Interacts with biogenesis of lysosome-related organelles complex-1 (BLOC1). Interacts with AP-3 complex.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: Microsome membrane

30608:LOC109730938
gene id: 30608:LOC109730938
uniprot id: A0A8B7X874
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Cytoplasm
messages: DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA.
messages: Homodimer.
messages: Nucleus
messages: P-body
messages: The CMP/dCMP deaminase domain 1 mediates RNA binding, RNA-dependent oligomerization and virion incorporation whereas the CMP/dCMP deaminase domain 2 confers deoxycytidine deaminase activity and substrate sequence specificity.

30608:EIF4G1
gene id: 30608:EIF4G1
uniprot id: A0A8B7ED69
uniprot id: A0A8B7EDR0
uniprot id: A0A8B7EDT8
uniprot id: A0A8B7EFT2
uniprot id: A0A8B7EFT7
uniprot id: A0A8B7X335
uniprot id: A0A8B7X4U9
uniprot id: A0A8C5YGE0
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

30608:ACTR1B
gene id: 30608:ACTR1B
uniprot id: A0A8C5UVB1
names: Similarity
messages: Belongs to the actin family.

30608:PSMD1
gene id: 30608:PSMD1
uniprot id: A0A8B7F9V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S1 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

30608:CKS2
gene id: 30608:CKS2
uniprot id: A0A8B7GZY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

30608:KYAT3
gene id: 30608:KYAT3
uniprot id: A0A8B7F9I5
names: Subunit
messages: Homodimer.

30608:FGD3
gene id: 30608:FGD3
uniprot id: A0A8B7XCB7
names: Subcellular Location Annotation
messages: cytoskeleton

30608:ACER1
gene id: 30608:ACER1
uniprot id: A0A8B7G651
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane

30608:LCN15
gene id: 30608:LCN15
uniprot id: A0A8B7HQ97
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

30608:SLC25A3
gene id: 30608:SLC25A3
uniprot id: A0A8B7HXX2
uniprot id: A0A8B7I0K6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Interacts with PPIF; the interaction is impaired by CsA.
messages: Membrane
messages: Mitochondrion inner membrane

30608:SETD3
gene id: 30608:SETD3
uniprot id: A0A8C5W9T7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
messages: Cytoplasm
messages: Interacts with MYOD1.

30608:TMEM229B
gene id: 30608:TMEM229B
uniprot id: A0A8B7HI12
uniprot id: A0A8B7HJU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM229 family.
messages: Membrane

30608:SLC43A2
gene id: 30608:SLC43A2
uniprot id: A0A8B7EMY0
uniprot id: A0A8B7EMY4
uniprot id: A0A8B7EN47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC43A transporter (TC 2.A.1.44) family.
messages: Membrane

30608:ZKSCAN4
gene id: 30608:ZKSCAN4
uniprot id: A0A8B7ET74
uniprot id: A0A8C5YDH8
names: Subcellular Location Annotation
messages: Nucleus

30608:NCL
gene id: 30608:NCL
uniprot id: A0A8C5UR88
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.
messages: nucleolus

30608:LOC105864539
gene id: 30608:LOC105864539
uniprot id: A0A8B7FHJ2
names: Subcellular Location Annotation
messages: Membrane

30608:ATXN1
gene id: 30608:ATXN1
uniprot id: A0A8B7FK14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

30608:HTR1E
gene id: 30608:HTR1E
uniprot id: A0A8B7FE02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CITED4
gene id: 30608:CITED4
uniprot id: A0A8B7EAM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

30608:LOC105883469
gene id: 30608:LOC105883469
uniprot id: A0A8B7HXI2
names: Subcellular Location Annotation
messages: Membrane

30608:ANP32B
gene id: 30608:ANP32B
uniprot id: A0A8B7GND1
names: Similarity
messages: Belongs to the ANP32 family.

30608:NAALADL1
gene id: 30608:NAALADL1
uniprot id: A0A8B7HCN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

30608:TYROBP
gene id: 30608:TYROBP
uniprot id: D1GFC3
uniprot id: D1GFC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TYROBP family.
messages: Cell membrane
messages: Membrane

30608:LOC105868739
gene id: 30608:LOC105868739
uniprot id: A0A8B7G148
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLAC1 family.
messages: Secreted

30608:RAB4B
gene id: 30608:RAB4B
uniprot id: A0A8B7H1H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

30608:ELSPBP1
gene id: 30608:ELSPBP1
uniprot id: A0A8B7G4H1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:RAB3IL1
gene id: 30608:RAB3IL1
uniprot id: A0A8B7HAG7
uniprot id: A0A8B7HAG8
uniprot id: A0A8B7HAG9
uniprot id: A0A8B7HAH1
uniprot id: A0A8B7HAH2
uniprot id: A0A8B7HD78
names: Similarity
messages: Belongs to the SEC2 family.

30608:LOC105878373
gene id: 30608:LOC105878373
uniprot id: A0A8B7H976
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

30608:CD70
gene id: 30608:CD70
uniprot id: A0A8B7G4T8
names: Similarity
messages: Belongs to the tumor necrosis factor family.

30608:SLC2A1
gene id: 30608:SLC2A1
uniprot id: A0A8C5W1T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane
messages: Photoreceptor inner segment

30608:OGFRL1
gene id: 30608:OGFRL1
uniprot id: A0A8B7FC52
uniprot id: A0A8C5XPR5
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

30608:ADSL
gene id: 30608:ADSL
uniprot id: A0A8B7ERN0
uniprot id: A0A8C5V1S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

30608:LOC105884126
gene id: 30608:LOC105884126
uniprot id: A0A8B7I167
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105884159
gene id: 30608:LOC105884159
uniprot id: A0A8B7I194
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ACAA1
gene id: 30608:ACAA1
uniprot id: A0A8B7FT31
uniprot id: A0A8B7X041
uniprot id: A0A8B7X1U0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

30608:LOC105881337
gene id: 30608:LOC105881337
uniprot id: A0A8B7HNZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

30608:KRT39
gene id: 30608:KRT39
uniprot id: A0A8C5UY07
names: Similarity
messages: Belongs to the intermediate filament family.

30608:LOC105863127
gene id: 30608:LOC105863127
uniprot id: A0A8B7FB20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SLC15A4
gene id: 30608:SLC15A4
uniprot id: A0A8B7WTP9
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

30608:UNC45B
gene id: 30608:UNC45B
uniprot id: A0A8C5XID5
names: Subcellular Location Annotation
messages: perinuclear region

30608:TSPAN33
gene id: 30608:TSPAN33
uniprot id: A0A8B7I1W4
uniprot id: A0A8C5XEK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

30608:FGF7
gene id: 30608:FGF7
uniprot id: A0A8C5VT41
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

30608:LOC105860526
gene id: 30608:LOC105860526
uniprot id: A0A8B7EZA3
uniprot id: A0A8B7F124
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:HNF1A
gene id: 30608:HNF1A
uniprot id: A0A8B7FSM9
uniprot id: A0A8B7FTM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

30608:KMT2D
gene id: 30608:KMT2D
uniprot id: A0A8B7G3A0
uniprot id: A0A8B7G3H5
uniprot id: A0A8B7G4D1
uniprot id: A0A8B7G4T7
uniprot id: A0A8B7X692
names: Subcellular Location Annotation
messages: Nucleus

30608:KCNMB3
gene id: 30608:KCNMB3
uniprot id: A0A8B7EDK2
uniprot id: A0A8C6ELA4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

30608:LOC105861766
gene id: 30608:LOC105861766
uniprot id: A0A8B7WSX4
uniprot id: A0A8C5V4D5
names: Similarity
messages: Belongs to the CLCR family.

30608:SDC3
gene id: 30608:SDC3
uniprot id: A0A8C5XJP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

30608:DES
gene id: 30608:DES
uniprot id: A0A8C5VD24
names: Similarity
messages: Belongs to the intermediate filament family.

30608:LOC105864576
gene id: 30608:LOC105864576
uniprot id: A0A8B7FHW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:DLST
gene id: 30608:DLST
uniprot id: A0A8B7ER71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

30608:SLC39A13
gene id: 30608:SLC39A13
uniprot id: A0A8B7I237
uniprot id: A0A8B7I249
uniprot id: A0A8B7I258
uniprot id: A0A8B7I264
uniprot id: A0A8B7I486
uniprot id: A0A8B7I528
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105884168
gene id: 30608:LOC105884168
uniprot id: A0A8B7HYM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:IZUMO1
gene id: 30608:IZUMO1
uniprot id: A0A8B7FMB4
uniprot id: A0A8B7FMH3
uniprot id: A0A8B7FMK8
uniprot id: A0A8B7WUD6
uniprot id: A0A8B7WVT1
names: Similarity
messages: Belongs to the Izumo family.

30608:LOC105864670
gene id: 30608:LOC105864670
uniprot id: A0A8B7FI47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:KAT7
gene id: 30608:KAT7
uniprot id: A0A8B7I334
uniprot id: A0A8B7I633
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

30608:LOC105855661
gene id: 30608:LOC105855661
uniprot id: A0A8B7EDF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:KRT23
gene id: 30608:KRT23
uniprot id: A0A8B7GEX6
names: Similarity
messages: Belongs to the intermediate filament family.

30608:AKIRIN1
gene id: 30608:AKIRIN1
uniprot id: A0A8B7HED5
uniprot id: A0A8B7HH17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

30608:GRIK1
gene id: 30608:GRIK1
uniprot id: A0A8B7HGW3
uniprot id: A0A8B7HGW8
uniprot id: A0A8B7HGZ7
uniprot id: A0A8B7HHN2
uniprot id: A0A8B7HJJ0
uniprot id: A0A8B7WY84
uniprot id: A0A8B7WY86
uniprot id: A0A8B7WYQ1
uniprot id: A0A8B7WZ57
uniprot id: A0A8C5XJU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

30608:IMPACT
gene id: 30608:IMPACT
uniprot id: A0A8B7F1L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

30608:LOC105864449
gene id: 30608:LOC105864449
uniprot id: A0A8B7FH77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SH3PXD2B
gene id: 30608:SH3PXD2B
uniprot id: A0A8B7GE43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm
messages: podosome

30608:PELI3
gene id: 30608:PELI3
uniprot id: A0A8B7FUU2
uniprot id: A0A8B7FV06
uniprot id: A0A8B7FVR0
uniprot id: A0A8B7FVU7
names: Function
names: Similarity
messages: Belongs to the pellino family.
messages: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

30608:LOC105871610
gene id: 30608:LOC105871610
uniprot id: A0A8B7GDJ0
names: Similarity
messages: Belongs to the peptidase M10A family.

30608:LHX1
gene id: 30608:LHX1
uniprot id: A0A8C5XSZ8
names: Subcellular Location Annotation
messages: Nucleus

30608:ELMO1
gene id: 30608:ELMO1
uniprot id: A0A8B7H8Q1
uniprot id: A0A8B7H8Q7
uniprot id: A0A8B7H8R3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

30608:TM4SF5
gene id: 30608:TM4SF5
uniprot id: A0A8B7HFW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

30608:SEZ6
gene id: 30608:SEZ6
uniprot id: A0A8B7EMR2
uniprot id: A0A8B7EP79
uniprot id: A0A8C5YH91
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105868203
gene id: 30608:LOC105868203
uniprot id: A0A8B7FXQ7
uniprot id: A0A8B7FYV0
names: Similarity
messages: Belongs to the TCP11 family.

30608:YWHAZ
gene id: 30608:YWHAZ
uniprot id: A0A8B7G6A9
names: Similarity
messages: Belongs to the 14-3-3 family.

30608:RIPPLY1
gene id: 30608:RIPPLY1
uniprot id: A0A8B7FE77
uniprot id: A0A8C6EHQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

30608:ESYT3
gene id: 30608:ESYT3
uniprot id: A0A8B7F978
uniprot id: A0A8B7F982
uniprot id: A0A8B7F998
uniprot id: A0A8B7F9D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:BLMH
gene id: 30608:BLMH
uniprot id: A0A8B7EMU9
uniprot id: A0A8B7EPC5
uniprot id: A0A8B7EQ34
uniprot id: A0A8C5WA62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm

30608:KRT4
gene id: 30608:KRT4
uniprot id: A0A8B7G8H0
uniprot id: A0A8B7G8I1
names: Similarity
messages: Belongs to the intermediate filament family.

30608:RAB21
gene id: 30608:RAB21
uniprot id: A0A8B7EI42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cleavage furrow
messages: Cytoplasmic vesicle membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: neuron projection
messages: trans-Golgi network

30608:MST1
gene id: 30608:MST1
uniprot id: A0A8B7GTP2
uniprot id: A0A8C5YH44
names: Caution
names: Similarity
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:FSHR
gene id: 30608:FSHR
uniprot id: A0A8B7FPQ8
uniprot id: A0A8B7FQS1
uniprot id: A0A8B7FQT5
uniprot id: A0A8B7XAG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
messages: Membrane

30608:ENO4
gene id: 30608:ENO4
uniprot id: A0A8B7H278
uniprot id: A0A8B7H2C4
uniprot id: A0A8B7H2E0
uniprot id: A0A8B7H4E6
names: Similarity
messages: Belongs to the enolase family.

30608:GNPNAT1
gene id: 30608:GNPNAT1
uniprot id: A0A8B7FW24
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. GNA1 subfamily.
messages: Homodimer.

30608:CD40
gene id: 30608:CD40
uniprot id: A0A8B7ETH2
uniprot id: A0A8B7EVD1
uniprot id: A0A8B7EVH1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:SPO11
gene id: 30608:SPO11
uniprot id: A0A8B7GRQ3
uniprot id: A0A8B7GRZ1
uniprot id: A0A8B7GTD7
uniprot id: A0A8C5UIR8
names: Similarity
messages: Belongs to the TOP6A family.

30608:AACS
gene id: 30608:AACS
uniprot id: A0A8B7HJM2
uniprot id: A0A8B7HM52
uniprot id: A0A8C5YGH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Converts acetoacetate to acetoacetyl-CoA in the cytosol.
messages: cytosol

30608:PCNT
gene id: 30608:PCNT
uniprot id: A0A8B7HES7
uniprot id: A0A8B7HET6
uniprot id: A0A8B7HEU1
uniprot id: A0A8B7HEU8
uniprot id: A0A8B7HEV4
uniprot id: A0A8B7HF75
uniprot id: A0A8B7HHH1
names: Subcellular Location Annotation
messages: centrosome

30608:FAM151B
gene id: 30608:FAM151B
uniprot id: A0A8C5XBC3
names: Similarity
messages: Belongs to the FAM151 family.

30608:POLR2F
gene id: 30608:POLR2F
uniprot id: A0A8C5XPN4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.
messages: Nucleus

30608:ERCC1
gene id: 30608:ERCC1
uniprot id: A0A8B7G4U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

30608:ARF1
gene id: 30608:ARF1
uniprot id: A0A8B7HB94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

30608:LOC105862655
gene id: 30608:LOC105862655
uniprot id: A0A8B7F968
names: Similarity
messages: Belongs to the PRR23 family.

30608:CPSF4L
gene id: 30608:CPSF4L
uniprot id: A0A8B7FRM7
uniprot id: A0A8B7FS36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

30608:FAM163B
gene id: 30608:FAM163B
uniprot id: A0A8B7HJ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

30608:SEZ6L
gene id: 30608:SEZ6L
uniprot id: A0A8B7FT77
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PPA1
gene id: 30608:PPA1
uniprot id: A0A8B7WLA6
names: Similarity
messages: Belongs to the PPase family.

30608:LOC105883347
gene id: 30608:LOC105883347
uniprot id: A0A8B7HWZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:GORASP1
gene id: 30608:GORASP1
uniprot id: A0A8B7ER92
uniprot id: A0A8B7ER93
uniprot id: A0A8C5YIL4
names: Similarity
messages: Belongs to the GORASP family.

30608:LOC105868206
gene id: 30608:LOC105868206
uniprot id: A0A8B7WPT4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

30608:PPEF1
gene id: 30608:PPEF1
uniprot id: A0A8B7HQK3
uniprot id: A0A8B7HSE5
uniprot id: A0A8B7HSZ3
names: Similarity
messages: Belongs to the PPP phosphatase family.

30608:ETS2
gene id: 30608:ETS2
uniprot id: A0A8B7HLA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus
messages: Transcription factor.

30608:UPF1
gene id: 30608:UPF1
uniprot id: A0A8B7EA53
uniprot id: A0A8B7EA85
uniprot id: A0A8B7EAE6
uniprot id: A0A8B7EAU6
uniprot id: A0A8B7EAV1
uniprot id: A0A8B7ECW8
uniprot id: A0A8B7ECX2
uniprot id: A0A8C5VG04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

30608:PTPRF
gene id: 30608:PTPRF
uniprot id: A0A8B7H4M9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

30608:PIK3R3
gene id: 30608:PIK3R3
uniprot id: A0A8B7H532
uniprot id: A0A8B7H533
uniprot id: A0A8B7H565
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

30608:LOC105860999
gene id: 30608:LOC105860999
uniprot id: A0A8B7F1H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

30608:BMP4
gene id: 30608:BMP4
uniprot id: A0A8B7FWU6
uniprot id: A0A8B7FWU8
names: Similarity
messages: Belongs to the TGF-beta family.

30608:SH2D1A
gene id: 30608:SH2D1A
uniprot id: A0A8B7FZL3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2.

30608:SERPINA4
gene id: 30608:SERPINA4
uniprot id: A0A8B7EI16
uniprot id: A0A8C5V4S9
names: Similarity
messages: Belongs to the serpin family.

30608:YWHAQ
gene id: 30608:YWHAQ
uniprot id: A0A8B7XB33
names: Function
names: Similarity
messages: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
messages: Belongs to the 14-3-3 family.

30608:GLRA1
gene id: 30608:GLRA1
uniprot id: A0A8B7EN39
uniprot id: A0A8B7EPL6
uniprot id: A0A8B7WWZ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite

30608:F2R
gene id: 30608:F2R
uniprot id: A0A8B7EHC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:RGS8
gene id: 30608:RGS8
uniprot id: A0A8B7EAN7
uniprot id: A0A8B7EB08
uniprot id: A0A8B7EB16
uniprot id: A0A8C5VRT7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: Perikaryon
messages: dendrite

30608:PAMR1
gene id: 30608:PAMR1
uniprot id: A0A8B7EHX7
uniprot id: A0A8B7EIB3
uniprot id: A0A8B7EKC8
uniprot id: A0A8C5XHI2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:TEKT5
gene id: 30608:TEKT5
uniprot id: A0A8B7HTT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

30608:SULT4A1
gene id: 30608:SULT4A1
uniprot id: A0A8B7FV44
uniprot id: A0A8B7FW16
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:ZDHHC1
gene id: 30608:ZDHHC1
uniprot id: A0A8B7ESJ0
uniprot id: A0A8B7ESJ1
uniprot id: A0A8B7ESJ2
uniprot id: A0A8B7EUK8
uniprot id: A0A8B7WTT5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

30608:ZFX
gene id: 30608:ZFX
uniprot id: A0A8B7HQB5
uniprot id: A0A8B7HQC1
names: Subcellular Location Annotation
messages: Nucleus

30608:MAP2K4
gene id: 30608:MAP2K4
uniprot id: A0A8B7H8M6
uniprot id: A0A8B7H8N5
uniprot id: A0A8C5VS12
uniprot id: A0A8C5W1W5
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:NPC1L1
gene id: 30608:NPC1L1
uniprot id: A0A8B7G9V2
uniprot id: A0A8B7XEQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

30608:CMTM2
gene id: 30608:CMTM2
uniprot id: A0A8B7WS60
uniprot id: A0A8C5UVG0
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105859234
gene id: 30608:LOC105859234
uniprot id: A0A8B7ET42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105884790
gene id: 30608:LOC105884790
uniprot id: A0A8B7I3P1
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Monomer.

30608:KIAA1429
gene id: 30608:KIAA1429
uniprot id: A0A8B7GXH2
uniprot id: A0A8B7X9S2
uniprot id: A0A8B7XBG2
names: Similarity
messages: Belongs to the vir family.

30608:TERF2
gene id: 30608:TERF2
uniprot id: A0A8B7EU16
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
messages: Homodimer.
messages: Nucleus
messages: telomere

30608:S100A16
gene id: 30608:S100A16
uniprot id: A0A8B7I6Y1
names: Similarity
messages: Belongs to the S-100 family.

30608:ARCN1
gene id: 30608:ARCN1
uniprot id: A0A8C5W7I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

30608:LOC105870428
gene id: 30608:LOC105870428
uniprot id: A0A8B7G927
uniprot id: A0A8B7WV93
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

30608:IMPDH2
gene id: 30608:IMPDH2
uniprot id: A0A8B7GTP1
uniprot id: A0A8B7WKY7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

30608:TGM6
gene id: 30608:TGM6
uniprot id: A0A8B7FMW7
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

30608:DENND6A
gene id: 30608:DENND6A
uniprot id: A0A8B7I257
uniprot id: A0A8B7WL28
uniprot id: A0A8B7WL35
uniprot id: A0A8B7WL56
uniprot id: A0A8B7WL74
uniprot id: A0A8B7WLY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Endosome
messages: Recycling endosome

30608:LOC105883120
gene id: 30608:LOC105883120
uniprot id: A0A8B7XDI4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

30608:LOC105858692
gene id: 30608:LOC105858692
uniprot id: A0A8C5UVD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:LOC105885321
gene id: 30608:LOC105885321
uniprot id: A0A8B7I4D2
names: Similarity
messages: Belongs to the NPIP family.

30608:NDUFB9
gene id: 30608:NDUFB9
uniprot id: A0A8B7HZH3
uniprot id: A0A8B7HZI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

30608:FAM83B
gene id: 30608:FAM83B
uniprot id: A0A8C5W043
names: Similarity
messages: Belongs to the FAM83 family.

30608:GAR1
gene id: 30608:GAR1
uniprot id: A0A8B7GFX0
uniprot id: A0A8B7GFY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

30608:KDM4B
gene id: 30608:KDM4B
uniprot id: A0A8C5Y409
names: Similarity
messages: Belongs to the JHDM3 histone demethylase family.

30608:ADAMTS13
gene id: 30608:ADAMTS13
uniprot id: A0A8B7HJ93
uniprot id: A0A8B7HJ97
uniprot id: A0A8B7HJA0
uniprot id: A0A8B7HKD4
uniprot id: A0A8B7XCE0
uniprot id: A0A8B7XD70
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:LOC105884903
gene id: 30608:LOC105884903
uniprot id: A0A8B7XA08
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:CFTR
gene id: 30608:CFTR
uniprot id: A0A8B7G362
uniprot id: A0A8B7G372
uniprot id: A0A8C5Y6D9
uniprot id: Q2QL83
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Binds and hydrolyzes ATP via the two cytoplasmic ABC transporter nucleotide-binding domains. The two ATP-binding domains interact with each other, forming a head-to-tail dimer. Normal ATPase activity requires interaction between the two domains. The first ABC transporter nucleotide-binding domain has no ATPase activity by itself.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3)(-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. Modulates the activity of the epithelial sodium channel (ENaC) complex, in part by regulating the cell surface expression of the ENaC complex. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the transporter SLC4A7. Can inhibit the chloride channel activity of ANO1 (By similarity). Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation (By similarity).
messages: Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer; does not require oligomerization for channel activity. May form oligomers in the membrane (By similarity). Interacts with SLC26A3, SLC26A6 and SLC9A3R1 (By similarity). Interacts with SHANK2 (By similarity). Interacts with MYO6 (By similarity). Interacts (via C-terminus) with GOPC (via PDZ domain); this promotes CFTR internalization and thereby decreases channel activity. Interacts with SLC4A7 through SLC9A3R1. Found in a complex with MYO5B and RAB11A. Interacts with ANO1. Interacts with SLC26A8 (By similarity). Interacts with AHCYL1; the interaction increases CFTR activity (By similarity). Interacts with CSE1L (By similarity). The core-glycosylated form interacts with GORASP2 (via PDZ GRASP-type 1 domain) in respone to ER stress (By similarity). Interacts with MARCHF2; the interaction leads to CFTR ubiqtuitination and degradation (By similarity).
messages: N-glycosylated.
messages: Nucleus
messages: Phosphorylated; cAMP treatment promotes phosphorylation and activates the channel. Dephosphorylation decreases the ATPase activity (in vitro). Phosphorylation at PKA sites activates the channel. Phosphorylation at PKC sites enhances the response to phosphorylation by PKA. Phosphorylated by AMPK; this inhibits channel activity.
messages: Recycling endosome membrane
messages: The PDZ-binding motif mediates interactions with GOPC and with the SLC4A7, SLC9A3R1/EBP50 complex.
messages: The disordered R region mediates channel activation when it is phosphorylated, but not in the absence of phosphorylation.
messages: Ubiquitinated, leading to its degradation in the lysosome. Deubiquitination by USP10 in early endosomes enhances its endocytic recycling to the cell membrane. Ubiquitinated by RNF185 during ER stress. Ubiquitinated by MARCHF2 (By similarity).

30608:ATG4C
gene id: 30608:ATG4C
uniprot id: A0A8B7GI72
uniprot id: A0A8B7GIV4
uniprot id: A0A8B7GIV9
uniprot id: A0A8B7GJ74
uniprot id: A0A8C5USP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

30608:PDIK1L
gene id: 30608:PDIK1L
uniprot id: A0A8B7FDL0
uniprot id: A0A8C5W2F8
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:BRINP2
gene id: 30608:BRINP2
uniprot id: A0A8C5XC96
names: Similarity
messages: Belongs to the BRINP family.

30608:IAH1
gene id: 30608:IAH1
uniprot id: A0A8B7HT06
uniprot id: A0A8B7HT19
uniprot id: A0A8B7HV32
uniprot id: A0A8B7XB38
uniprot id: A0A8C5UN05
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

30608:SMAD5
gene id: 30608:SMAD5
uniprot id: A0A8B7G498
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

30608:DYRK1A
gene id: 30608:DYRK1A
uniprot id: A0A8B7HLB3
uniprot id: A0A8B7HLB7
uniprot id: A0A8B7HLC0
uniprot id: A0A8C5VDN6
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

30608:ACTN4
gene id: 30608:ACTN4
uniprot id: A0A8B7H1W4
uniprot id: A0A8B7H1W8
uniprot id: A0A8B7H1W9
uniprot id: A0A8B7H220
uniprot id: A0A8B7H3Z3
uniprot id: A0A8C5XHF2
names: Similarity
messages: Belongs to the alpha-actinin family.

30608:LOC109730287
gene id: 30608:LOC109730287
uniprot id: A0A8B7WZY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
messages: Virion

30608:LOC105882326
gene id: 30608:LOC105882326
uniprot id: A0A8B7HQA3
uniprot id: A0A8B7HQB7
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

30608:TMEM205
gene id: 30608:TMEM205
uniprot id: A0A8B7I5A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM205 family.
messages: Membrane

30608:ZNF397
gene id: 30608:ZNF397
uniprot id: A0A8B7ER68
names: Subcellular Location Annotation
messages: Nucleus

30608:HSPH1
gene id: 30608:HSPH1
uniprot id: A0A8B7F284
uniprot id: A0A8C5W422
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm

30608:PPP2CA
gene id: 30608:PPP2CA
uniprot id: A0A8B7G5V5
names: Similarity
messages: Belongs to the PPP phosphatase family.

30608:SESN1
gene id: 30608:SESN1
uniprot id: A0A8B7FIZ2
uniprot id: A0A8B7FJ17
uniprot id: A0A8B7FKD5
uniprot id: A0A8C5XLV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

30608:WNT9A
gene id: 30608:WNT9A
uniprot id: A0A8B7HB98
uniprot id: A0A8B7HBA0
uniprot id: A0A8C5Y6M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

30608:PPP1R16A
gene id: 30608:PPP1R16A
uniprot id: A0A8B7G0M8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:DYNLT1
gene id: 30608:DYNLT1
uniprot id: A0A8B7G0Q5
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

30608:LOC105880835
gene id: 30608:LOC105880835
uniprot id: A0A8B7HJL2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:TP63
gene id: 30608:TP63
uniprot id: A0A8B7EYW8
uniprot id: A0A8B7EYX1
uniprot id: A0A8B7EYX2
uniprot id: A0A8B7EYX3
uniprot id: A0A8B7F0N8
uniprot id: A0A8B7F0P3
uniprot id: A0A8B7F122
uniprot id: A0A8B7X543
uniprot id: A0A8C5YI40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Binds DNA as a homotetramer. Isoform composition of the tetramer may determine transactivation activity.
messages: Cytoplasm
messages: Nucleus

30608:LOC105863936
gene id: 30608:LOC105863936
uniprot id: A0A8B7FF77
uniprot id: A0A8B7FFD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

30608:AMT
gene id: 30608:AMT
uniprot id: A0A8B7GTL0
uniprot id: A0A8B7GTT5
uniprot id: A0A8B7GVD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

30608:SLC2A4
gene id: 30608:SLC2A4
uniprot id: A0A8B7H707
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Endomembrane system
messages: Membrane
messages: perinuclear region

30608:PDPK1
gene id: 30608:PDPK1
uniprot id: A0A8B7EV53
uniprot id: A0A8B7EV54
uniprot id: A0A8B7EV60
uniprot id: A0A8B7EX50
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

30608:LOC105856976
gene id: 30608:LOC105856976
uniprot id: A0A8B7EIP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:MME
gene id: 30608:MME
uniprot id: A0A8B7H150
uniprot id: A0A8B7H166
names: Cofactor
messages: Binds 1 zinc ion per subunit.

30608:TOPAZ1
gene id: 30608:TOPAZ1
uniprot id: A0A8B7GRG2
uniprot id: A0A8B7GRH0
names: Function
names: Subcellular Location Annotation
messages: Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear.
messages: cytosol

30608:MARVELD1
gene id: 30608:MARVELD1
uniprot id: A0A8B7GJY8
names: Subcellular Location Annotation
messages: Membrane

30608:IL15
gene id: 30608:IL15
uniprot id: A0A8B7HNH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

30608:TIMM50
gene id: 30608:TIMM50
uniprot id: A0A8B7H1Q2
uniprot id: A0A8B7WVF5
uniprot id: A0A8C5VI57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

30608:TMEM267
gene id: 30608:TMEM267
uniprot id: A0A8B7ELZ2
names: Subcellular Location Annotation
messages: Membrane

30608:TNKS
gene id: 30608:TNKS
uniprot id: A0A8B7EKH4
uniprot id: A0A8C5Y6B2
names: Similarity
messages: Belongs to the ARTD/PARP family.

30608:ECHS1
gene id: 30608:ECHS1
uniprot id: A0A8C5YA48
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

30608:OAS3
gene id: 30608:OAS3
uniprot id: A0A8B7FRY6
uniprot id: A0A8B7FS21
uniprot id: A0A8B7FSK3
uniprot id: A0A8B7FT08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-5A synthase family.
messages: Cytoplasm

30608:LOC105883083
gene id: 30608:LOC105883083
uniprot id: A0A8B7HVR0
uniprot id: A0A8B7WWR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

30608:PCID2
gene id: 30608:PCID2
uniprot id: A0A8B7GER8
names: Similarity
messages: Belongs to the CSN12 family.

30608:LOC105884298
gene id: 30608:LOC105884298
uniprot id: A0A8B7I137
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

30608:APC
gene id: 30608:APC
uniprot id: A0A8B7G9N5
uniprot id: A0A8B7G9N8
uniprot id: A0A8B7G9P1
uniprot id: A0A8B7G9P4
uniprot id: A0A8B7G9Z5
uniprot id: A0A8B7GAA7
uniprot id: A0A8C5UJU6
names: Similarity
messages: Belongs to the adenomatous polyposis coli (APC) family.

30608:PLPP5
gene id: 30608:PLPP5
uniprot id: A0A8B7WSX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

30608:B4GALT5
gene id: 30608:B4GALT5
uniprot id: A0A8C5VNC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

30608:AXIN1
gene id: 30608:AXIN1
uniprot id: A0A8B7EFF9
uniprot id: A0A8B7EFG8
uniprot id: A0A8B7EHZ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus

30608:LOC105876421
gene id: 30608:LOC105876421
uniprot id: A0A8B7GHH5
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

30608:LOC105871465
gene id: 30608:LOC105871465
uniprot id: A0A8B7GDB3
names: Subcellular Location Annotation
messages: Membrane

30608:KCNH4
gene id: 30608:KCNH4
uniprot id: A0A8B7EU11
uniprot id: A0A8B7EU12
uniprot id: A0A8B7EVZ8
uniprot id: A0A8C5XVE5
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

30608:ALDH1B1
gene id: 30608:ALDH1B1
uniprot id: A0A8B7GN46
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

30608:L3MBTL3
gene id: 30608:L3MBTL3
uniprot id: A0A8B7ECG1
uniprot id: A0A8B7ECG9
uniprot id: A0A8B7ECH0
uniprot id: A0A8B7ECW5
uniprot id: A0A8B7ECX1
uniprot id: A0A8B7ED28
uniprot id: A0A8B7EF41
uniprot id: A0A8C5VMR4
uniprot id: A0A8C6EH44
names: Subcellular Location Annotation
messages: Nucleus

30608:TMEM86B
gene id: 30608:TMEM86B
uniprot id: A0A8B7H3Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

30608:APOOL
gene id: 30608:APOOL
uniprot id: A0A8B7I435
uniprot id: A0A8C5W0A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

30608:RPL27A
gene id: 30608:RPL27A
uniprot id: A0A8B7HNV8
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

30608:HIP1
gene id: 30608:HIP1
uniprot id: A0A8B7ERC1
uniprot id: A0A8B7ERC2
uniprot id: A0A8B7ERD8
uniprot id: A0A8B7ET38
uniprot id: A0A8B7ET43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLA2 family.
messages: Membrane

30608:GRIN2A
gene id: 30608:GRIN2A
uniprot id: A0A8B7HRT6
uniprot id: A0A8B7HRU7
uniprot id: A0A8B7HTS9
uniprot id: A0A8B7HU34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

30608:TRPT1
gene id: 30608:TRPT1
uniprot id: A0A8B7X394
uniprot id: A0A8B7X455
uniprot id: A0A8C5XKQ5
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

30608:RIF1
gene id: 30608:RIF1
uniprot id: A0A8B7HEJ2
uniprot id: A0A8C5Y6Z6
uniprot id: A0A8C5Y997
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

30608:FZD5
gene id: 30608:FZD5
uniprot id: A0A8C5Y6V2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:CASC4
gene id: 30608:CASC4
uniprot id: A0A8B7GH67
uniprot id: A0A8B7GH73
uniprot id: A0A8B7GHV8
uniprot id: A0A8B7GI19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

30608:AK4
gene id: 30608:AK4
uniprot id: A0A8B7GIM7
uniprot id: A0A8B7GIX6
uniprot id: A0A8B7X901
uniprot id: A0A8B7XAM6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP/ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP/ATP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.
messages: Mitochondrion matrix
messages: Monomer.

30608:LOC105869919
gene id: 30608:LOC105869919
uniprot id: A0A8B7G6W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Membrane

30608:SERPING1
gene id: 30608:SERPING1
uniprot id: A0A8B7FB76
uniprot id: A0A8B7FB80
names: Similarity
messages: Belongs to the serpin family.

30608:CRK
gene id: 30608:CRK
uniprot id: A0A8C5XT69
names: Similarity
messages: Belongs to the CRK family.

30608:LOC105861329
gene id: 30608:LOC105861329
uniprot id: A0A8B7F461
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CROT
gene id: 30608:CROT
uniprot id: A0A8B7HG53
uniprot id: A0A8C5ULL9
uniprot id: A0A8C6EKC4
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

30608:LOC105860211
gene id: 30608:LOC105860211
uniprot id: A0A8B7EXU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

30608:KREMEN1
gene id: 30608:KREMEN1
uniprot id: A0A8B7WU32
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.

30608:NDRG2
gene id: 30608:NDRG2
uniprot id: A0A8B7FHY8
uniprot id: A0A8B7FI19
uniprot id: A0A8C5W1L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDRG family.
messages: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation.
messages: Cytoplasm
messages: growth cone

30608:ABCG1
gene id: 30608:ABCG1
uniprot id: A0A8B7FAX7
uniprot id: A0A8B7FAY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

30608:FAM8A1
gene id: 30608:FAM8A1
uniprot id: A0A8B7FLL9
names: Subcellular Location Annotation
messages: Membrane

30608:FAM83C
gene id: 30608:FAM83C
uniprot id: A0A8B7WRS3
names: Similarity
messages: Belongs to the FAM83 family.

30608:PQLC3
gene id: 30608:PQLC3
uniprot id: A0A8B7X923
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105885296
gene id: 30608:LOC105885296
uniprot id: A0A8B7I448
names: Similarity
messages: Belongs to the peptidase M16 family.

30608:LOC105878114
gene id: 30608:LOC105878114
uniprot id: A0A8B7WX29
uniprot id: A0A8B7WY20
uniprot id: A0A8C5XTQ0
names: Similarity
messages: Belongs to the SELO family.

30608:PRKD2
gene id: 30608:PRKD2
uniprot id: A0A8B7G462
uniprot id: A0A8C5VBU8
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

30608:TMEM132A
gene id: 30608:TMEM132A
uniprot id: A0A8B7HAP7
uniprot id: A0A8B7HAP9
uniprot id: A0A8B7HAQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

30608:LOC105882596
gene id: 30608:LOC105882596
uniprot id: A0A8B7HU29
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:MAPRE1
gene id: 30608:MAPRE1
uniprot id: A0A8B7FNP9
uniprot id: A0A8C5YED7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: centrosome
messages: spindle pole

30608:ITIH2
gene id: 30608:ITIH2
uniprot id: A0A8B7WXY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

30608:LOC105883776
gene id: 30608:LOC105883776
uniprot id: A0A8B7HX03
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

30608:MARCH4
gene id: 30608:MARCH4
uniprot id: A0A8C5VJ81
names: Subcellular Location Annotation
messages: Membrane

30608:KIF23
gene id: 30608:KIF23
uniprot id: A0A8B7GLA2
uniprot id: A0A8B7GLB1
uniprot id: A0A8B7GLV9
uniprot id: A0A8B7GLW4
uniprot id: A0A8B7GMJ8
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:GGT5
gene id: 30608:GGT5
uniprot id: A0A8B7F9L5
uniprot id: A0A8B7FA40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

30608:BORCS5
gene id: 30608:BORCS5
uniprot id: A0A8B7H1A9
uniprot id: A0A8B7H1G5
uniprot id: A0A8B7H3C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS5 family.
messages: Lysosome membrane
messages: Membrane

30608:DOCK4
gene id: 30608:DOCK4
uniprot id: A0A8B7EB98
uniprot id: A0A8B7EBA3
uniprot id: A0A8B7EBC8
uniprot id: A0A8B7EBM2
uniprot id: A0A8B7EBM8
uniprot id: A0A8B7EBY6
uniprot id: A0A8B7EDZ5
uniprot id: A0A8B7EDZ9
uniprot id: A0A8B7XDS0
names: Similarity
messages: Belongs to the DOCK family.

30608:TACR3
gene id: 30608:TACR3
uniprot id: A0A8C5YGA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TRAPPC11
gene id: 30608:TRAPPC11
uniprot id: A0A8B7HRD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPPC11 family.
messages: Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
messages: cis-Golgi network

30608:LOC105857182
gene id: 30608:LOC105857182
uniprot id: A0A8B7X212
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

30608:PATL1
gene id: 30608:PATL1
uniprot id: A0A8B7G046
names: Similarity
messages: Belongs to the PAT1 family.

30608:ZNF408
gene id: 30608:ZNF408
uniprot id: A0A8B7I2N8
uniprot id: A0A8B7I4N2
uniprot id: A0A8B7I5M0
names: Subcellular Location Annotation
messages: Nucleus

30608:DGKZ
gene id: 30608:DGKZ
uniprot id: A0A8B7I3F8
uniprot id: A0A8B7I3G8
uniprot id: A0A8B7I3H7
uniprot id: A0A8B7I3K3
uniprot id: A0A8B7I3K6
uniprot id: A0A8B7I3K7
uniprot id: A0A8B7I3N1
uniprot id: A0A8B7I3N8
uniprot id: A0A8B7I3N9
uniprot id: A0A8B7I3P6
uniprot id: A0A8B7I6M1
uniprot id: A0A8B7I6M6
uniprot id: A0A8B7X2Z5
uniprot id: A0A8B7X4E9
uniprot id: A0A8B7X4Q8
uniprot id: A0A8C5VXJ4
uniprot id: A0A8C5XWP6
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

30608:MRPL37
gene id: 30608:MRPL37
uniprot id: A0A8C5UM23
names: Subcellular Location Annotation
messages: Mitochondrion

30608:COMTD1
gene id: 30608:COMTD1
uniprot id: A0A8B7FQ81
uniprot id: A0A8B7FQ93
uniprot id: A0A8B7FQK5
uniprot id: A0A8B7FR94
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

30608:ATG4B
gene id: 30608:ATG4B
uniprot id: A0A8B7FQG0
uniprot id: A0A8C5W719
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Endoplasmic reticulum
messages: Mitochondrion
messages: autophagosome
messages: cytosol

30608:ULK3
gene id: 30608:ULK3
uniprot id: A0A8B7ECH6
uniprot id: A0A8C5UW64
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:ATP5G1
gene id: 30608:ATP5G1
uniprot id: A0A8B7I2Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

30608:UBA2
gene id: 30608:UBA2
uniprot id: A0A8B7H534
uniprot id: A0A8C5V0B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.
messages: Nucleus
messages: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

30608:GPR156
gene id: 30608:GPR156
uniprot id: A0A8B7HFZ6
uniprot id: A0A8B7HG31
uniprot id: A0A8B7X5N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

30608:CORO7
gene id: 30608:CORO7
uniprot id: A0A8B7EVB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat coronin family.
messages: Cytoplasmic vesicle
messages: F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology.
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicle
messages: cytosol
messages: trans-Golgi network

30608:CLASP1
gene id: 30608:CLASP1
uniprot id: A0A8B7F637
uniprot id: A0A8B7F638
uniprot id: A0A8B7F639
uniprot id: A0A8B7F642
uniprot id: A0A8B7F644
uniprot id: A0A8B7F647
uniprot id: A0A8B7F648
uniprot id: A0A8B7F651
uniprot id: A0A8B7F652
uniprot id: A0A8B7F653
uniprot id: A0A8B7F655
uniprot id: A0A8B7F656
uniprot id: A0A8B7F658
uniprot id: A0A8B7F659
uniprot id: A0A8B7F661
uniprot id: A0A8B7F662
uniprot id: A0A8B7F663
uniprot id: A0A8B7F665
uniprot id: A0A8B7F666
uniprot id: A0A8B7F667
uniprot id: A0A8B7F670
uniprot id: A0A8B7F673
uniprot id: A0A8B7F675
uniprot id: A0A8B7F680
uniprot id: A0A8B7F681
uniprot id: A0A8B7F687
uniprot id: A0A8B7F691
uniprot id: A0A8B7F697
uniprot id: A0A8B7F6A2
uniprot id: A0A8B7F6A8
uniprot id: A0A8B7X8P8
uniprot id: A0A8B7X8Q0
uniprot id: A0A8B7XAC7
uniprot id: A0A8B7XAR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLASP family.
messages: centrosome
messages: kinetochore
messages: trans-Golgi network

30608:SEC24C
gene id: 30608:SEC24C
uniprot id: A0A8B7G118
uniprot id: A0A8B7G126
uniprot id: A0A8C5XG97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

30608:LOC105870382
gene id: 30608:LOC105870382
uniprot id: A0A8B7G7T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative pheromone receptor.

30608:ADIPOR2
gene id: 30608:ADIPOR2
uniprot id: A0A8B7F4R6
uniprot id: A0A8B7F4S2
uniprot id: A0A8B7F4S6
uniprot id: A0A8B7F4T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

30608:CMPK2
gene id: 30608:CMPK2
uniprot id: A0A8B7G9U1
names: Similarity
messages: Belongs to the thymidylate kinase family.

30608:MAT2A
gene id: 30608:MAT2A
uniprot id: A0A8C5XXH9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

30608:LOC105862247
gene id: 30608:LOC105862247
uniprot id: A0A8B7F7X0
names: Subcellular Location Annotation
messages: Membrane

30608:SARDH
gene id: 30608:SARDH
uniprot id: A0A8B7XDP9
names: Similarity
messages: Belongs to the GcvT family.

30608:C2H1orf123
gene id: 30608:C2H1orf123
uniprot id: A0A8B7H5N3
uniprot id: A0A8B7H5Q9
uniprot id: A0A8B7XAX5
names: Similarity
messages: Belongs to the UPF0587 family.

30608:LOC105858864
gene id: 30608:LOC105858864
uniprot id: A0A8B7ETB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105876723
gene id: 30608:LOC105876723
uniprot id: A0A8B7WSK7
names: Similarity
messages: Belongs to the serpin family.

30608:AP1G1
gene id: 30608:AP1G1
uniprot id: A0A8B7ES78
uniprot id: A0A8B7ES80
uniprot id: A0A8B7EU03
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

30608:LOC105863124
gene id: 30608:LOC105863124
uniprot id: A0A8B7FB33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Endoplasmic reticulum membrane

30608:BMP2
gene id: 30608:BMP2
uniprot id: A0A8C5YCH5
names: Similarity
messages: Belongs to the TGF-beta family.

30608:ECHDC1
gene id: 30608:ECHDC1
uniprot id: A0A8B7H8G8
uniprot id: A0A8B7H8H8
uniprot id: A0A8B7HB39
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

30608:LOC105874566
gene id: 30608:LOC105874566
uniprot id: A0A8B7GS20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

30608:LOC105884169
gene id: 30608:LOC105884169
uniprot id: A0A8B7HYM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TERF2IP
gene id: 30608:TERF2IP
uniprot id: A0A8C5XXF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression.
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Nucleus
messages: telomere

30608:GPM6A
gene id: 30608:GPM6A
uniprot id: A0A8B7GSJ6
uniprot id: A0A8B7GTX7
uniprot id: A0A8C5XBF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

30608:S100A12
gene id: 30608:S100A12
uniprot id: A0A8B7I8P9
names: Similarity
messages: Belongs to the S-100 family.

30608:FAM98A
gene id: 30608:FAM98A
uniprot id: A0A8B7HZZ6
names: Similarity
messages: Belongs to the FAM98 family.

30608:PAX6
gene id: 30608:PAX6
uniprot id: A0A8B7EKL4
uniprot id: A0A8B7ELX2
uniprot id: A0A8B7ELX8
uniprot id: A0A8B7EMX7
uniprot id: A0A8B7X3L9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

30608:FUBP1
gene id: 30608:FUBP1
uniprot id: A0A8B7HXI3
uniprot id: A0A8B7WRW3
uniprot id: A0A8B7WRX6
uniprot id: A0A8B7WRY1
uniprot id: A0A8B7WRY6
uniprot id: A0A8B7WRY9
uniprot id: A0A8B7WRZ0
uniprot id: A0A8B7WS04
uniprot id: A0A8B7WS05
uniprot id: A0A8B7WS09
uniprot id: A0A8B7WS15
uniprot id: A0A8B7WS21
uniprot id: A0A8B7WS27
uniprot id: A0A8B7WTE4
uniprot id: A0A8B7WTF8
uniprot id: A0A8B7WTG2
uniprot id: A0A8B7WTG7
names: Subcellular Location Annotation
messages: Nucleus

30608:MEOX2
gene id: 30608:MEOX2
uniprot id: A0A8B7EQT7
names: Subcellular Location Annotation
messages: Nucleus

30608:GRPEL1
gene id: 30608:GRPEL1
uniprot id: A0A8C5Y965
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

30608:LOC105858719
gene id: 30608:LOC105858719
uniprot id: A0A8B7EQZ0
uniprot id: A0A8B7ER13
names: Subcellular Location Annotation
messages: Nucleus

30608:TAS2R3
gene id: 30608:TAS2R3
uniprot id: A0A8B7GL68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

30608:TLR3
gene id: 30608:TLR3
uniprot id: A0A8B7HR43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

30608:RPL36
gene id: 30608:RPL36
uniprot id: A0A8C5W5J2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

30608:RIPPLY2
gene id: 30608:RIPPLY2
uniprot id: A0A8B7GNY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

30608:PITHD1
gene id: 30608:PITHD1
uniprot id: A0A8C5XC50
names: Similarity
messages: Belongs to the PITHD1 family.

30608:RND3
gene id: 30608:RND3
uniprot id: A0A8B7HEY8
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

30608:MRPL24
gene id: 30608:MRPL24
uniprot id: A0A8B7GKB9
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

30608:INPP5D
gene id: 30608:INPP5D
uniprot id: A0A8B7I7Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane

30608:ZMPSTE24
gene id: 30608:ZMPSTE24
uniprot id: A0A8C5UJW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

30608:TUBGCP6
gene id: 30608:TUBGCP6
uniprot id: A0A8B7X6A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: centrosome

30608:KRI1
gene id: 30608:KRI1
uniprot id: A0A8B7I5C1
names: Similarity
messages: Belongs to the KRI1 family.

30608:GNG4
gene id: 30608:GNG4
uniprot id: A0A8B7EHN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

30608:LOC105872044
gene id: 30608:LOC105872044
uniprot id: A0A8B7GEV9
names: Similarity
messages: Belongs to the intermediate filament family.

30608:FOXL1
gene id: 30608:FOXL1
uniprot id: A0A8B7GC09
names: Subcellular Location Annotation
messages: Nucleus

30608:BTN1A1
gene id: 30608:BTN1A1
uniprot id: A0A8B7ER56
uniprot id: A0A8C5V8E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

30608:ADAMTS8
gene id: 30608:ADAMTS8
uniprot id: A0A8B7HMD3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:GIMD1
gene id: 30608:GIMD1
uniprot id: A0A8B7HCC8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

30608:ADAM12
gene id: 30608:ADAM12
uniprot id: A0A8B7HHV3
uniprot id: A0A8B7HKF8
uniprot id: A0A8C5Y2I4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:SOX6
gene id: 30608:SOX6
uniprot id: A0A8B7HGA8
uniprot id: A0A8B7HGB2
uniprot id: A0A8B7HGB3
uniprot id: A0A8B7HGB7
uniprot id: A0A8B7HGC2
uniprot id: A0A8B7HGC4
uniprot id: A0A8B7HGC6
uniprot id: A0A8B7HGE5
uniprot id: A0A8B7HGF4
uniprot id: A0A8B7HH08
uniprot id: A0A8B7HH30
uniprot id: A0A8B7HIY8
uniprot id: A0A8B7HIZ3
uniprot id: A0A8B7HJ03
uniprot id: A0A8B7HJ10
uniprot id: A0A8B7X351
uniprot id: A0A8B7X4V9
uniprot id: A0A8C5VY43
names: Subcellular Location Annotation
messages: Nucleus

30608:PROK2
gene id: 30608:PROK2
uniprot id: A0A8B7WZ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

30608:LOC105855009
gene id: 30608:LOC105855009
uniprot id: A0A8B7WVL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPE family.
messages: Cytoplasm
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

30608:INTS3
gene id: 30608:INTS3
uniprot id: A0A8B7I6V6
uniprot id: A0A8B7I6Z0
names: Similarity
messages: Belongs to the Integrator subunit 3 family.

30608:SLC45A2
gene id: 30608:SLC45A2
uniprot id: A0A8B7FX49
names: Subcellular Location Annotation
messages: Membrane

30608:MVB12A
gene id: 30608:MVB12A
uniprot id: A0A8B7WW08
uniprot id: A0A8C5YFB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

30608:TMCO3
gene id: 30608:TMCO3
uniprot id: A0A8B7GEZ6
uniprot id: A0A8B7GF46
names: Subcellular Location Annotation
messages: Membrane

30608:STX3
gene id: 30608:STX3
uniprot id: A0A8B7G080
uniprot id: A0A8B7G085
uniprot id: A0A8B7G094
uniprot id: A0A8B7G142
uniprot id: A0A8B7G1I2
names: Similarity
messages: Belongs to the syntaxin family.

30608:CCL20
gene id: 30608:CCL20
uniprot id: A0A8B7FAR9
uniprot id: A0A8C5VVM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

30608:SLC39A1
gene id: 30608:SLC39A1
uniprot id: A0A8C5VFR6
names: Subcellular Location Annotation
messages: Membrane

30608:AHCY
gene id: 30608:AHCY
uniprot id: A0A8B7FN19
uniprot id: A0A8B7FP63
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

30608:BMP8B
gene id: 30608:BMP8B
uniprot id: A0A8B7XAT0
names: Similarity
messages: Belongs to the TGF-beta family.

30608:GPX3
gene id: 30608:GPX3
uniprot id: A0A8B7ENA5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

30608:LOC105856398
gene id: 30608:LOC105856398
uniprot id: A0A8C5YC89
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

30608:TRAPPC9
gene id: 30608:TRAPPC9
uniprot id: A0A8B7XAT7
names: Similarity
messages: Belongs to the NIBP family.

30608:IPO9
gene id: 30608:IPO9
uniprot id: A0A8B7EWZ5
uniprot id: A0A8C5UV67
names: Subcellular Location Annotation
messages: Cytoplasm

30608:PPP2R2C
gene id: 30608:PPP2R2C
uniprot id: A0A8B7F5V6
uniprot id: A0A8B7F5W1
uniprot id: A0A8B7F5W7
uniprot id: A0A8B7F5Y9
uniprot id: A0A8B7F5Z4
uniprot id: A0A8C5VNA9
uniprot id: A0A8C5XT30
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

30608:SELENOT
gene id: 30608:SELENOT
uniprot id: A0A8B7HL81
names: Similarity
messages: Belongs to the SelWTH family. Selenoprotein T subfamily.

30608:PRKACA
gene id: 30608:PRKACA
uniprot id: A0A8C5VRY8
uniprot id: A0A8C5XSM8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

30608:N6AMT1
gene id: 30608:N6AMT1
uniprot id: A0A8B7GBY4
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

30608:IDS
gene id: 30608:IDS
uniprot id: A0A8B7EKW5
uniprot id: A0A8B7ELC3
uniprot id: A0A8B7EN49
uniprot id: A0A8B7ENB6
uniprot id: A0A8C6EKM1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

30608:CD59
gene id: 30608:CD59
uniprot id: A0A8B7EL12
uniprot id: A0A8B7EN11
names: Subunit
messages: Interacts with T-cell surface antigen CD2.

30608:USP8
gene id: 30608:USP8
uniprot id: A0A8B7X1X3
uniprot id: A0A8B7X2K6
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

30608:LOC105868175
gene id: 30608:LOC105868175
uniprot id: A0A8B7WX61
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105877463
gene id: 30608:LOC105877463
uniprot id: A0A8B7H4Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL18 family.
messages: Rough endoplasmic reticulum

30608:DNAJB14
gene id: 30608:DNAJB14
uniprot id: A0A8B7EH21
uniprot id: A0A8B7WY51
uniprot id: A0A8B7WYK0
names: Subcellular Location Annotation
messages: Membrane

30608:RARS
gene id: 30608:RARS
uniprot id: A0A8B7WV73
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

30608:LOC105884107
gene id: 30608:LOC105884107
uniprot id: A0A8B7HYG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PRDX2
gene id: 30608:PRDX2
uniprot id: A0A8C5YGQ0
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

30608:SLC17A6
gene id: 30608:SLC17A6
uniprot id: A0A8B7EAK1
names: Subcellular Location Annotation
messages: Membrane

30608:SIN3A
gene id: 30608:SIN3A
uniprot id: A0A8B7E9S3
uniprot id: A0A8B7EA97
names: Subcellular Location Annotation
messages: Nucleus

30608:IMP4
gene id: 30608:IMP4
uniprot id: A0A8B7G3W1
uniprot id: A0A8C5UY81
names: Subcellular Location Annotation
messages: nucleolus

30608:CLN3
gene id: 30608:CLN3
uniprot id: A0A8C5VQV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Lysosome membrane
messages: Membrane

30608:TLR7
gene id: 30608:TLR7
uniprot id: A0A8B7HQX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Endoplasmic reticulum membrane
messages: Lysosome
messages: Membrane
messages: phagosome

30608:LOC109729598
gene id: 30608:LOC109729598
uniprot id: A0A8B7WQN7
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:CRTC2
gene id: 30608:CRTC2
uniprot id: A0A8B7I6U5
uniprot id: A0A8B7I6Z6
uniprot id: A0A8B7I8V3
uniprot id: A0A8B7IA56
uniprot id: A0A8C5VSA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

30608:SVBP
gene id: 30608:SVBP
uniprot id: A0A8B7XED6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVBP family.
messages: Secreted
messages: cytoskeleton

30608:HSD17B1
gene id: 30608:HSD17B1
uniprot id: A0A8B7ETX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Favors the reduction of estrogens and androgens. Uses preferentially NADH.

30608:CTSZ
gene id: 30608:CTSZ
uniprot id: A0A8C5V2V2
names: Similarity
messages: Belongs to the peptidase C1 family.

30608:GLTSCR2
gene id: 30608:GLTSCR2
uniprot id: A0A8B7WUN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: nucleolus
messages: nucleoplasm

30608:GPN2
gene id: 30608:GPN2
uniprot id: A0A8B7FD38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

30608:TMEM88
gene id: 30608:TMEM88
uniprot id: A0A8C5VGG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

30608:CDC123
gene id: 30608:CDC123
uniprot id: A0A8B7GFE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Required for S phase entry of the cell cycle.

30608:ALG8
gene id: 30608:ALG8
uniprot id: A0A8B7X3X3
uniprot id: A0A8B7X4W2
uniprot id: A0A8B7X537
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:HTR3C
gene id: 30608:HTR3C
uniprot id: A0A8B7EG81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

30608:LOC105869236
gene id: 30608:LOC105869236
uniprot id: A0A8C5V1F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

30608:GINS2
gene id: 30608:GINS2
uniprot id: A0A8B7GCJ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus

30608:MIPEP
gene id: 30608:MIPEP
uniprot id: A0A8B7XFR8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

30608:SLC35B3
gene id: 30608:SLC35B3
uniprot id: A0A8B7FKD7
uniprot id: A0A8B7FKH3
uniprot id: A0A8B7FKL9
uniprot id: A0A8B7FLT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

30608:HMGB1
gene id: 30608:HMGB1
uniprot id: A0A8B7F3Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Cell membrane
messages: Chromosome
messages: Endoplasmic reticulum-Golgi intermediate compartment
messages: Secreted

30608:UNKL
gene id: 30608:UNKL
uniprot id: A0A8B7WP18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

30608:LOC105865706
gene id: 30608:LOC105865706
uniprot id: A0A8B7FMN5
names: Caution
names: Function
messages: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:HADH
gene id: 30608:HADH
uniprot id: A0A8B7GG25
uniprot id: A0A8B7GG34
uniprot id: A0A8C5VHV5
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

30608:NDUFAF2
gene id: 30608:NDUFAF2
uniprot id: A0A8B7XDA4
names: Similarity
messages: Belongs to the complex I NDUFA12 subunit family.

30608:LOC105876079
gene id: 30608:LOC105876079
uniprot id: A0A8B7GZI5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

30608:MAP7
gene id: 30608:MAP7
uniprot id: A0A8B7EJN6
uniprot id: A0A8B7EJN8
uniprot id: A0A8B7EJP2
uniprot id: A0A8B7EK03
uniprot id: A0A8B7EKV6
uniprot id: A0A8B7EKW1
uniprot id: A0A8B7EKW6
uniprot id: A0A8B7EM21
uniprot id: A0A8B7EM26
uniprot id: A0A8C5XQW3
names: Similarity
messages: Belongs to the MAP7 family.

30608:GUCA2B
gene id: 30608:GUCA2B
uniprot id: A0A8B7GE81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

30608:LOC105858676
gene id: 30608:LOC105858676
uniprot id: A0A8C5V9L5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

30608:VGLL4
gene id: 30608:VGLL4
uniprot id: A0A8B7HS17
uniprot id: A0A8C5XTS4
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

30608:LIFR
gene id: 30608:LIFR
uniprot id: A0A8B7EET1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

30608:SMPX
gene id: 30608:SMPX
uniprot id: A0A8B7HQE8
names: Function
names: Similarity
messages: Belongs to the SMPX family.
messages: Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair.

30608:NRXN1
gene id: 30608:NRXN1
uniprot id: A0A8B7FWB6
uniprot id: A0A8B7FWC0
uniprot id: A0A8B7FWJ2
uniprot id: A0A8B7FXA8
uniprot id: A0A8B7FXB1
uniprot id: A0A8B7FXB6
uniprot id: A0A8B7X8S4
uniprot id: A0A8B7X8S6
uniprot id: A0A8B7X8T0
uniprot id: A0A8B7X8T1
uniprot id: A0A8B7X8T3
uniprot id: A0A8B7X9H5
uniprot id: A0A8B7X9H9
uniprot id: A0A8B7X9I4
uniprot id: A0A8B7XAF6
uniprot id: A0A8B7XAG1
uniprot id: A0A8B7XAT5
uniprot id: A0A8B7XAU0
uniprot id: A0A8C5Y8V8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:EFEMP2
gene id: 30608:EFEMP2
uniprot id: A0A8B7HA61
uniprot id: A0A8B7HA62
uniprot id: A0A8B7HA63
uniprot id: A0A8B7HCX5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:GCN1
gene id: 30608:GCN1
uniprot id: A0A8B7FSW5
names: Similarity
messages: Belongs to the GCN1 family.

30608:CDHR5
gene id: 30608:CDHR5
uniprot id: A0A8B7X4E3
names: Similarity
messages: Belongs to the glucagon family.

30608:ANXA1
gene id: 30608:ANXA1
uniprot id: A0A8C5V4S5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Belongs to the annexin family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome membrane
messages: Lateral cell membrane
messages: Membrane
messages: Nucleus
messages: The full-length protein can bind eight Ca(2+) ions via the annexin repeats. Calcium binding causes a major conformation change that modifies dimer contacts and leads to surface exposure of the N-terminal phosphorylation sites; in the absence of Ca(2+), these sites are buried in the interior of the protein core. The N-terminal region becomes disordered in response to calcium-binding.
messages: cilium
messages: extracellular exosome
messages: extracellular space
messages: phagocytic cup
messages: secretory vesicle lumen

30608:CLCA4
gene id: 30608:CLCA4
uniprot id: A0A8B7F5I8
names: Similarity
messages: Belongs to the CLCR family.

30608:ARMCX4
gene id: 30608:ARMCX4
uniprot id: A0A8B7WZR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eutherian X-chromosome-specific Armcx family.
messages: Membrane

30608:AOC2
gene id: 30608:AOC2
uniprot id: A0A8B7WM71
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

30608:LOC105868422
gene id: 30608:LOC105868422
uniprot id: A0A8B7FYY1
names: Similarity
messages: Belongs to the MHC class I family.

30608:MRPL53
gene id: 30608:MRPL53
uniprot id: A0A8B7I0H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

30608:PFKFB1
gene id: 30608:PFKFB1
uniprot id: A0A8B7WZ79
uniprot id: A0A8B7WZ82
uniprot id: A0A8B7X093
uniprot id: A0A8C5Y6R7
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

30608:RNF167
gene id: 30608:RNF167
uniprot id: A0A8C5V256
names: Subcellular Location Annotation
messages: Membrane

30608:CRTC3
gene id: 30608:CRTC3
uniprot id: A0A8B7XA90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

30608:PRKDC
gene id: 30608:PRKDC
uniprot id: A0A8B7I3V7
uniprot id: A0A8B7I3W9
uniprot id: A0A8B7I5W5
uniprot id: A0A8B7I6X8
uniprot id: A0A8B7X9C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family.
messages: nucleolus

30608:NEK8
gene id: 30608:NEK8
uniprot id: A0A8B7EME9
uniprot id: A0A8B7EMM3
uniprot id: A0A8B7ENV2
uniprot id: A0A8B7EPL8
uniprot id: A0A8B7EPM5
uniprot id: A0A8B7WNI2
uniprot id: A0A8B7WPQ0
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

30608:TNFRSF1B
gene id: 30608:TNFRSF1B
uniprot id: A0A8B7HUG2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SH3YL1
gene id: 30608:SH3YL1
uniprot id: A0A8B7HM67
uniprot id: A0A8B7XB64
names: Similarity
names: Subunit
messages: Belongs to the SH3YL1 family.
messages: Interacts with SH3D19.

30608:B3GALT5
gene id: 30608:B3GALT5
uniprot id: A0A8B7HLB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:EXT2
gene id: 30608:EXT2
uniprot id: A0A8B7I6U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:PCYT2
gene id: 30608:PCYT2
uniprot id: A0A8B7I2D6
uniprot id: A0A8B7I2E9
uniprot id: A0A8B7I5D2
uniprot id: A0A8C5V9N6
names: Similarity
messages: Belongs to the cytidylyltransferase family.

30608:STK3
gene id: 30608:STK3
uniprot id: A0A8B7G5F3
uniprot id: A0A8C5VN44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

30608:CDO1
gene id: 30608:CDO1
uniprot id: A0A8C5Y207
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.

30608:B4GALT2
gene id: 30608:B4GALT2
uniprot id: A0A8B7H4R1
uniprot id: A0A8B7H4V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

30608:CFAP53
gene id: 30608:CFAP53
uniprot id: A0A8B7GRR5
uniprot id: A0A8B7WQV2
names: Similarity
messages: Belongs to the CFAP53 family.

30608:DYM
gene id: 30608:DYM
uniprot id: A0A8B7GQ88
uniprot id: A0A8B7GQN1
names: Similarity
messages: Belongs to the dymeclin family.

30608:GNL2
gene id: 30608:GNL2
uniprot id: A0A8C5V3B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

30608:GPHA2
gene id: 30608:GPHA2
uniprot id: A0A0F7RQG7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:SEC16A
gene id: 30608:SEC16A
uniprot id: A0A8B7HJC8
uniprot id: A0A8B7HJD0
uniprot id: A0A8B7HJD1
uniprot id: A0A8B7HKG7
uniprot id: A0A8B7HLX5
uniprot id: A0A8B7HLY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

30608:TMEM55B
gene id: 30608:TMEM55B
uniprot id: A0A8B7FIA0
uniprot id: A0A8C5XTZ7
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: phagosome membrane

30608:BARX1
gene id: 30608:BARX1
uniprot id: A0A8C5XVM5
names: Subcellular Location Annotation
messages: Nucleus

30608:SERPINA7
gene id: 30608:SERPINA7
uniprot id: A0A8B7HZ22
uniprot id: A0A8B7HZH0
names: Similarity
messages: Belongs to the serpin family.

30608:TPPP2
gene id: 30608:TPPP2
uniprot id: A0A8B7FJC4
names: Similarity
messages: Belongs to the TPPP family.

30608:LOC105863192
gene id: 30608:LOC105863192
uniprot id: A0A8B7X0B8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

30608:LOC105865502
gene id: 30608:LOC105865502
uniprot id: A0A8B7FLQ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:KIF24
gene id: 30608:KIF24
uniprot id: A0A8B7GQV4
uniprot id: A0A8B7XD74
uniprot id: A0A8C6EFV4
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:RPL37
gene id: 30608:RPL37
uniprot id: A0A8B7H996
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

30608:LOC109730745
gene id: 30608:LOC109730745
uniprot id: A0A8B7X5R1
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6c family.

30608:PTPN2
gene id: 30608:PTPN2
uniprot id: A0A8B7F1H6
uniprot id: A0A8B7F1H7
uniprot id: A0A8B7F3N1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

30608:BSN
gene id: 30608:BSN
uniprot id: A0A8B7GVD9
names: Subcellular Location Annotation
messages: Presynaptic active zone

30608:USP22
gene id: 30608:USP22
uniprot id: A0A8B7WNG3
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

30608:GABBR2
gene id: 30608:GABBR2
uniprot id: A0A8B7GN13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

30608:LOC105878411
gene id: 30608:LOC105878411
uniprot id: A0A8B7H995
uniprot id: A0A8B7H999
uniprot id: A0A8B7H9B0
uniprot id: A0A8B7HC09
uniprot id: A0A8B7HC15
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

30608:LOC105883337
gene id: 30608:LOC105883337
uniprot id: A0A8B7HUU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ACTR5
gene id: 30608:ACTR5
uniprot id: A0A8B7FQK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family. ARP5 subfamily.
messages: Nucleus

30608:SENP5
gene id: 30608:SENP5
uniprot id: A0A8B7HFD5
uniprot id: A0A8B7HFD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

30608:PNPT1
gene id: 30608:PNPT1
uniprot id: A0A8B7H9E1
uniprot id: A0A8B7HC52
names: Similarity
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.

30608:LOC105872185
gene id: 30608:LOC105872185
uniprot id: A0A8B7GGC3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

30608:ATP6V0E2
gene id: 30608:ATP6V0E2
uniprot id: A0A8B7HU19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane

30608:LOC105865922
gene id: 30608:LOC105865922
uniprot id: A0A8B7FPS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:C5H11orf87
gene id: 30608:C5H11orf87
uniprot id: A0A8B7GZP1
names: Subcellular Location Annotation
messages: Membrane

30608:MRPS2
gene id: 30608:MRPS2
uniprot id: A0A8B7HJH9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

30608:MAFB
gene id: 30608:MAFB
uniprot id: A0A8C5VP02
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

30608:LOC105876737
gene id: 30608:LOC105876737
uniprot id: A0A8B7H1F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF152 family.
messages: Lysosome membrane
messages: Membrane

30608:FLNA
gene id: 30608:FLNA
uniprot id: A0A8B7FW83
uniprot id: A0A8B7FW85
uniprot id: A0A8B7FWF6
uniprot id: A0A8B7FX77
uniprot id: A0A8B7WZ98
uniprot id: A0A8C5UTZ6
names: Similarity
messages: Belongs to the filamin family.

30608:LOC105884466
gene id: 30608:LOC105884466
uniprot id: A0A8B7I2A4
names: Similarity
messages: Belongs to the Schlafen family. Subgroup III subfamily.

30608:LOC105873313
gene id: 30608:LOC105873313
uniprot id: A0A8B7GKR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SYNE2
gene id: 30608:SYNE2
uniprot id: A0A8B7X0V4
uniprot id: A0A8B7X0V6
uniprot id: A0A8B7X2M2
names: Similarity
messages: Belongs to the nesprin family.

30608:SGK1
gene id: 30608:SGK1
uniprot id: A0A8B7EM55
uniprot id: A0A8C5V9U2
uniprot id: A0A8C5Y119
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

30608:SPPL2A
gene id: 30608:SPPL2A
uniprot id: A0A8B7G921
uniprot id: A0A8B7G926
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

30608:CCSER2
gene id: 30608:CCSER2
uniprot id: A0A8B7GC23
uniprot id: A0A8B7GC33
uniprot id: A0A8B7GCM6
uniprot id: A0A8B7GCN2
uniprot id: A0A8B7GD26
uniprot id: A0A8C5V5M3
uniprot id: A0A8C5XTC6
uniprot id: A0A8C5XXT0
names: Similarity
messages: Belongs to the CCSER family.

30608:LOC105858691
gene id: 30608:LOC105858691
uniprot id: A0A8C5UVD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:SF3B5
gene id: 30608:SF3B5
uniprot id: A0A8B7FT63
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

30608:LOC105864540
gene id: 30608:LOC105864540
uniprot id: A0A8B7FIS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:DTX1
gene id: 30608:DTX1
uniprot id: A0A8B7WT85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

30608:NPPB
gene id: 30608:NPPB
uniprot id: A0A8B7HU57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

30608:DDX53
gene id: 30608:DDX53
uniprot id: A0A8B7HQE9
names: Similarity
messages: Belongs to the DEAD box helicase family.

30608:USP15
gene id: 30608:USP15
uniprot id: A0A8B7HK30
uniprot id: A0A8B7HK31
uniprot id: A0A8B7HK33
uniprot id: A0A8B7HK36
uniprot id: A0A8B7HLA0
uniprot id: A0A8B7HMM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Nucleus

30608:FAM189A2
gene id: 30608:FAM189A2
uniprot id: A0A8B7XBK1
names: Similarity
messages: Belongs to the ENTREP family.

30608:SLC20A2
gene id: 30608:SLC20A2
uniprot id: A0A8B7WT50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

30608:MFSD9
gene id: 30608:MFSD9
uniprot id: A0A8B7ENP0
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105866620
gene id: 30608:LOC105866620
uniprot id: A0A8B7FRD2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:LIPI
gene id: 30608:LIPI
uniprot id: A0A8B7HTR2
uniprot id: A0A8B7HTS0
uniprot id: A0A8B7HVS8
uniprot id: A0A8B7HVZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

30608:SLC7A3
gene id: 30608:SLC7A3
uniprot id: A0A8B7EBD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

30608:MAP1LC3A
gene id: 30608:MAP1LC3A
uniprot id: A0A8B7FN01
names: Similarity
messages: Belongs to the ATG8 family.

30608:METAP1D
gene id: 30608:METAP1D
uniprot id: A0A8B7HJ55
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

30608:MLN
gene id: 30608:MLN
uniprot id: A0A8B7F350
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the motilin family.
messages: Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
messages: Secreted

30608:LIMS2
gene id: 30608:LIMS2
uniprot id: A0A8B7X8R1
uniprot id: A0A8C5XN29
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.
messages: Cell membrane
messages: Part of the heterotrimeric IPP complex composed of integrin-linked kinase (ILK), LIMS1 or LIMS2, and PARVA.
messages: focal adhesion

30608:LOC105862101
gene id: 30608:LOC105862101
uniprot id: A0A8B7X5Y3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PSAPL1
gene id: 30608:PSAPL1
uniprot id: A0A8B7HMQ6
names: Subcellular Location Annotation
messages: Secreted

30608:LOC105874387
gene id: 30608:LOC105874387
uniprot id: A0A8B7GQZ1
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:IRF7
gene id: 30608:IRF7
uniprot id: A0A8B7GP86
uniprot id: A0A8B7GPI8
uniprot id: A0A8B7GPP2
uniprot id: A0A8B7GQQ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

30608:BAAT
gene id: 30608:BAAT
uniprot id: A0A8B7GMV2
uniprot id: A0A8B7GP73
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

30608:CALCRL
gene id: 30608:CALCRL
uniprot id: A0A8C5VY22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.
messages: Membrane
messages: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

30608:ELOVL7
gene id: 30608:ELOVL7
uniprot id: A0A8B7H441
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL7 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:RPE
gene id: 30608:RPE
uniprot id: A0A8B7FF23
uniprot id: A0A8B7FF42
uniprot id: A0A8B7FFA4
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

30608:MYO9B
gene id: 30608:MYO9B
uniprot id: A0A8B7WY70
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

30608:SST
gene id: 30608:SST
uniprot id: A0A8B7I4Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted

30608:LOC105883510
gene id: 30608:LOC105883510
uniprot id: A0A8B7HVG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ZNRF4
gene id: 30608:ZNRF4
uniprot id: A0A8B7G4V9
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105884083
gene id: 30608:LOC105884083
uniprot id: A0A8B7HYF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SAMD4B
gene id: 30608:SAMD4B
uniprot id: A0A8B7H3T6
uniprot id: A0A8C5UTJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

30608:LOC105873355
gene id: 30608:LOC105873355
uniprot id: A0A8B7XEU8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LOC105857919
gene id: 30608:LOC105857919
uniprot id: A0A8B7EML5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

30608:S1PR1
gene id: 30608:S1PR1
uniprot id: A0A8B7F7N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MOB3B
gene id: 30608:MOB3B
uniprot id: A0A8B7GBV6
names: Similarity
messages: Belongs to the MOB1/phocein family.

30608:C7H12orf75
gene id: 30608:C7H12orf75
uniprot id: A0A8C6EHN6
names: Similarity
messages: Belongs to the OCC1 family.

30608:COL4A3
gene id: 30608:COL4A3
uniprot id: A0A8B7F9X1
uniprot id: A0A8B7X882
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

30608:TCP11L2
gene id: 30608:TCP11L2
uniprot id: A0A8B7GXA8
uniprot id: A0A8B7GXG4
uniprot id: A0A8B7GZ75
names: Similarity
messages: Belongs to the TCP11 family.

30608:LOC105870047
gene id: 30608:LOC105870047
uniprot id: A0A8B7G7G4
uniprot id: A0A8B7X7M0
names: Similarity
messages: Belongs to the NRAMP family.

30608:DNAH2
gene id: 30608:DNAH2
uniprot id: A0A8B7H4H3
uniprot id: A0A8B7H4L6
names: Similarity
messages: Belongs to the dynein heavy chain family.

30608:RPL38
gene id: 30608:RPL38
uniprot id: A0A8B7HBH3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

30608:LOC105863050
gene id: 30608:LOC105863050
uniprot id: A0A8B7FB12
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK. The mature dimeric form interacts with PPP1R16B (via its fourth ankyrin repeat). Interacts with PPP1CA only in the presence of PPP1R16B.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

30608:HOXC11
gene id: 30608:HOXC11
uniprot id: A0A8B7GAI7
uniprot id: A0A8B7X5J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

30608:ADCY4
gene id: 30608:ADCY4
uniprot id: A0A8B7FRC8
uniprot id: A0A8C5XB42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

30608:ST6GALNAC4
gene id: 30608:ST6GALNAC4
uniprot id: A0A8B7GVN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

30608:LOC105869720
gene id: 30608:LOC105869720
uniprot id: A0A8B7G4U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PRKAB2
gene id: 30608:PRKAB2
uniprot id: A0A8B7G571
uniprot id: A0A8B7G5Y7
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

30608:PFKFB4
gene id: 30608:PFKFB4
uniprot id: A0A8B7GTD4
uniprot id: A0A8B7GTJ3
uniprot id: A0A8B7GTK7
uniprot id: A0A8B7GV51
uniprot id: A0A8C5VB42
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

30608:LOC105878206
gene id: 30608:LOC105878206
uniprot id: A0A8B7H8L8
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

30608:FAM83A
gene id: 30608:FAM83A
uniprot id: A0A8C5VD26
names: Similarity
messages: Belongs to the FAM83 family.

30608:KHDC3L
gene id: 30608:KHDC3L
uniprot id: A0A8B7X5B6
names: Similarity
messages: Belongs to the KHDC1 family.

30608:LOC105871931
gene id: 30608:LOC105871931
uniprot id: A0A8B7GEC2
uniprot id: A0A8B7GEC5
uniprot id: A0A8B7GEV1
uniprot id: A0A8B7GF36
uniprot id: A0A8B7GF86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative pheromone receptor.

30608:CMTM8
gene id: 30608:CMTM8
uniprot id: A0A8B7GNF2
names: Subcellular Location Annotation
messages: Membrane

30608:ADRA1D
gene id: 30608:ADRA1D
uniprot id: A0A8B7FPI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA.
messages: Membrane
messages: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

30608:AIP
gene id: 30608:AIP
uniprot id: A0A8B7FV13
uniprot id: A0A8B7FVY8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with RET in the pituitary gland; this interaction prevents the formation of the AIP-survivin complex.
messages: May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting.

30608:GGCX
gene id: 30608:GGCX
uniprot id: A0A8B7H0W1
uniprot id: A0A8B7H0W8
uniprot id: A0A8B7H0X5
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.
messages: Membrane

30608:POLR2D
gene id: 30608:POLR2D
uniprot id: A0A8B7EM47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

30608:LOC105870495
gene id: 30608:LOC105870495
uniprot id: A0A8B7WPK8
names: Similarity
messages: Belongs to the Bcl-2 family.

30608:LSM14B
gene id: 30608:LSM14B
uniprot id: A0A8B7GXK9
uniprot id: A0A8B7GXQ9
uniprot id: A0A8B7GZG8
uniprot id: A0A8C5VJY3
names: Similarity
messages: Belongs to the LSM14 family.

30608:SLC6A7
gene id: 30608:SLC6A7
uniprot id: A0A8B7EQ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

30608:PGR
gene id: 30608:PGR
uniprot id: A0A8B7GRX0
uniprot id: A0A8B7GS55
uniprot id: A0A8B7GS74
uniprot id: A0A8B7GTK1
uniprot id: A0A8C5Y0Q3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Cytoplasm
messages: Nucleus
messages: Steroid hormone receptor involved in the regulation of eukaryotic gene expression which affects cellular proliferation and differentiation in target tissues.

30608:MOSPD1
gene id: 30608:MOSPD1
uniprot id: A0A8B7GDA9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

30608:EED
gene id: 30608:EED
uniprot id: A0A8B7EHT9
uniprot id: A0A8B7EI76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ESC family.
messages: Nucleus

30608:ATP1A4
gene id: 30608:ATP1A4
uniprot id: A0A8B7F9C9
uniprot id: A0A8B7F9D0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:OPRK1
gene id: 30608:OPRK1
uniprot id: A0A8B7F2D3
uniprot id: A0A8B7X9E0
uniprot id: A0A8B7XB23
uniprot id: A0A8C5XVU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
messages: Interacts with SLC9A3R1. Interacts with GABARAPL1.
messages: Membrane

30608:GRM5
gene id: 30608:GRM5
uniprot id: A0A8B7EYU7
uniprot id: A0A8B7EYV0
uniprot id: A0A8C5Y5A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

30608:SLC7A6OS
gene id: 30608:SLC7A6OS
uniprot id: A0A8B7ERS5
uniprot id: A0A8C5Y8I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWR1/SLC7A6OS family.
messages: Cytoplasm
messages: Directs RNA polymerase II nuclear import.
messages: Nucleus

30608:TSPAN7
gene id: 30608:TSPAN7
uniprot id: A0A8C5XTE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

30608:ARID1B
gene id: 30608:ARID1B
uniprot id: A0A8B7FZK4
uniprot id: A0A8B7FZK9
uniprot id: A0A8B7FZL7
uniprot id: A0A8B7FZM4
uniprot id: A0A8B7FZP4
uniprot id: A0A8B7FZQ0
uniprot id: A0A8B7G0H9
uniprot id: A0A8B7G0I6
uniprot id: A0A8B7G0U6
uniprot id: A0A8B7G0W3
uniprot id: A0A8C5XH89
names: Subcellular Location Annotation
messages: Nucleus

30608:GCLM
gene id: 30608:GCLM
uniprot id: A0A8B7I657
names: Similarity
names: Subunit
messages: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
messages: Heterodimer of a catalytic heavy chain and a regulatory light chain.

30608:LCN12
gene id: 30608:LCN12
uniprot id: A0A8B7HQ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

30608:DNASE2
gene id: 30608:DNASE2
uniprot id: A0A8B7I4V5
names: Similarity
messages: Belongs to the DNase II family.

30608:LOC105861332
gene id: 30608:LOC105861332
uniprot id: A0A8B7F2Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CRYZ
gene id: 30608:CRYZ
uniprot id: A0A8B7I008
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

30608:NEU2
gene id: 30608:NEU2
uniprot id: A0A8C6EEI1
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

30608:IL18
gene id: 30608:IL18
uniprot id: A0A8B7FAA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Cytoplasm
messages: Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
messages: Secreted

30608:LYG2
gene id: 30608:LYG2
uniprot id: A0A8B7X2W4
uniprot id: A0A8C5XZZ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

30608:MFAP1
gene id: 30608:MFAP1
uniprot id: A0A8B7GHK5
names: Function
names: Similarity
messages: Belongs to the MFAP1 family.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.

30608:PIEZO1
gene id: 30608:PIEZO1
uniprot id: A0A8B7WSS5
uniprot id: A0A8B7WU75
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIEZO (TC 1.A.75) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:CLTC
gene id: 30608:CLTC
uniprot id: A0A8B7GR88
uniprot id: A0A8B7GRI5
uniprot id: A0A8B7GRQ9
uniprot id: A0A8C5VAQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

30608:SLC16A11
gene id: 30608:SLC16A11
uniprot id: A0A8B7H7Z5
uniprot id: A0A8B7H7Z7
names: Subcellular Location Annotation
messages: Membrane

30608:SLC41A1
gene id: 30608:SLC41A1
uniprot id: A0A8C5VMK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

30608:CDC42EP2
gene id: 30608:CDC42EP2
uniprot id: A0A8B7H9Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

30608:INSM1
gene id: 30608:INSM1
uniprot id: A0A8B7FUI4
names: Subcellular Location Annotation
messages: Nucleus

30608:SLC2A13
gene id: 30608:SLC2A13
uniprot id: A0A8C5XNA4
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

30608:LOC105873215
gene id: 30608:LOC105873215
uniprot id: A0A8C5W9L7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

30608:LAMC1
gene id: 30608:LAMC1
uniprot id: A0A8C5VBB7
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

30608:CD164L2
gene id: 30608:CD164L2
uniprot id: A0A8B7FD10
uniprot id: A0A8B7FD73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

30608:LTB4R2
gene id: 30608:LTB4R2
uniprot id: A0A8B7FRB0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:ZDHHC13
gene id: 30608:ZDHHC13
uniprot id: A0A8B7FSX6
uniprot id: A0A8C5XF03
names: Caution
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

30608:MED27
gene id: 30608:MED27
uniprot id: A0A8B7EY18
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 27 family.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

30608:TMOD2
gene id: 30608:TMOD2
uniprot id: A0A8B7G996
names: Subcellular Location Annotation
messages: cytoskeleton

30608:LOC105859732
gene id: 30608:LOC105859732
uniprot id: A0A8B7EVF1
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:MMP25
gene id: 30608:MMP25
uniprot id: A0A8B7EXK7
names: Similarity
messages: Belongs to the peptidase M10A family.

30608:GALNT18
gene id: 30608:GALNT18
uniprot id: A0A8B7HSU8
uniprot id: A0A8C5XMX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

30608:DDX52
gene id: 30608:DDX52
uniprot id: A0A8B7EPT8
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.

30608:ATG16L1
gene id: 30608:ATG16L1
uniprot id: A0A8B7I7N9
uniprot id: A0A8C5XUA1
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

30608:TRAF3
gene id: 30608:TRAF3
uniprot id: A0A8B7F1V4
uniprot id: A0A8C5Y3U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

30608:TAS1R3
gene id: 30608:TAS1R3
uniprot id: A0A8B7H5Z4
uniprot id: A0A8B7H609
uniprot id: A0A8C5Y0L6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:LOC105862433
gene id: 30608:LOC105862433
uniprot id: A0A8B7F892
names: Subcellular Location Annotation
messages: Membrane

30608:SELENOO
gene id: 30608:SELENOO
uniprot id: A0A8B7I5R9
uniprot id: A0A8B7X7C0
names: Similarity
messages: Belongs to the SELO family.

30608:DIMT1
gene id: 30608:DIMT1
uniprot id: A0A8B7HRG5
uniprot id: A0A8B7XEX9
uniprot id: A0A8C5VZ50
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ABCB11
gene id: 30608:ABCB11
uniprot id: A0A8B7X8A9
names: Subcellular Location Annotation
messages: Endosome

30608:CXXC1
gene id: 30608:CXXC1
uniprot id: A0A8B7GQ44
uniprot id: A0A8B7GQD8
uniprot id: A0A8B7GQJ7
uniprot id: A0A8B7GRN8
names: Subcellular Location Annotation
messages: Nucleus

30608:SSC5D
gene id: 30608:SSC5D
uniprot id: A0A8B7FC18
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:GOLM1
gene id: 30608:GOLM1
uniprot id: A0A8B7HX28
uniprot id: A0A8B7HZ67
uniprot id: A0A8B7HZM3
uniprot id: A0A8C5XF61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

30608:RPS26
gene id: 30608:RPS26
uniprot id: A0A8B7X7N3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

30608:NCAM1
gene id: 30608:NCAM1
uniprot id: A0A8B7G373
uniprot id: A0A8B7G375
uniprot id: A0A8B7G379
uniprot id: A0A8B7G380
uniprot id: A0A8B7G381
uniprot id: A0A8B7G384
uniprot id: A0A8B7G385
uniprot id: A0A8B7G386
uniprot id: A0A8B7G389
uniprot id: A0A8B7G390
uniprot id: A0A8B7G391
uniprot id: A0A8B7G395
uniprot id: A0A8B7G423
uniprot id: A0A8B7G428
uniprot id: A0A8B7G431
uniprot id: A0A8B7G436
uniprot id: A0A8B7G4L7
uniprot id: A0A8B7G4M2
uniprot id: A0A8B7G4N1
uniprot id: A0A8B7G4N6
uniprot id: A0A8C5XRI3
names: Function
messages: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.

30608:RIC8B
gene id: 30608:RIC8B
uniprot id: A0A8B7GXD1
uniprot id: A0A8B7GXH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

30608:TFAP2D
gene id: 30608:TFAP2D
uniprot id: A0A8C5UQN5
names: Similarity
messages: Belongs to the AP-2 family.

30608:ZDHHC9
gene id: 30608:ZDHHC9
uniprot id: A0A8C5V8H0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

30608:ZC3H12C
gene id: 30608:ZC3H12C
uniprot id: A0A8B7GZP3
uniprot id: A0A8B7GZP6
uniprot id: A0A8B7GZP7
uniprot id: A0A8B7GZV2
uniprot id: A0A8B7GZV7
uniprot id: A0A8B7H1M3
names: Similarity
messages: Belongs to the ZC3H12 family.

30608:FAM83F
gene id: 30608:FAM83F
uniprot id: A0A8C5V4D3
names: Similarity
messages: Belongs to the FAM83 family.

30608:ILDR1
gene id: 30608:ILDR1
uniprot id: A0A8B7HFX8
uniprot id: A0A8B7HIH9
uniprot id: A0A8B7X4W1
uniprot id: A0A8B7X5G5
uniprot id: A0A8B7X6R1
uniprot id: A0A8B7X6R6
uniprot id: A0A8C5YHE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

30608:MSH2
gene id: 30608:MSH2
uniprot id: A0A8B7FQN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

30608:RPS20
gene id: 30608:RPS20
uniprot id: A0A8B7H0M3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

30608:LRRFIP1
gene id: 30608:LRRFIP1
uniprot id: A0A8B7FQ70
uniprot id: A0A8B7FQ74
uniprot id: A0A8B7FQ79
uniprot id: A0A8B7FQ85
uniprot id: A0A8B7FQC1
uniprot id: A0A8B7FQC7
uniprot id: A0A8B7FQD2
uniprot id: A0A8B7FQD7
uniprot id: A0A8B7FQD9
uniprot id: A0A8B7FQF0
uniprot id: A0A8B7FQF5
uniprot id: A0A8B7FQR1
uniprot id: A0A8B7FQR6
uniprot id: A0A8B7FQS2
uniprot id: A0A8B7FQS6
uniprot id: A0A8B7FRD8
uniprot id: A0A8B7FRE4
uniprot id: A0A8B7FRE8
uniprot id: A0A8B7FRF3
uniprot id: A0A8B7X783
uniprot id: A0A8B7X8X7
names: Similarity
messages: Belongs to the LRRFIP family.

30608:CERS6
gene id: 30608:CERS6
uniprot id: A0A8B7HLI0
uniprot id: A0A8C5Y5P7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

30608:CLIC1
gene id: 30608:CLIC1
uniprot id: A0A8C5VHS1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cell membrane
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane
messages: Nucleus membrane

30608:MMS19
gene id: 30608:MMS19
uniprot id: A0A8B7GJA5
uniprot id: A0A8B7GJB4
uniprot id: A0A8B7GK07
uniprot id: A0A8B7GK17
uniprot id: A0A8B7GKG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MET18/MMS19 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus
messages: spindle

30608:THNSL1
gene id: 30608:THNSL1
uniprot id: A0A8B7H891
names: Similarity
messages: Belongs to the threonine synthase family.

30608:CDNF
gene id: 30608:CDNF
uniprot id: A0A8C5W857
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

30608:DNMT3A
gene id: 30608:DNMT3A
uniprot id: A0A8B7HZ81
uniprot id: A0A8B7HZ86
uniprot id: A0A8B7HZ87
uniprot id: A0A8B7HZ88
uniprot id: A0A8B7XAN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

30608:MRPS11
gene id: 30608:MRPS11
uniprot id: A0A8C5V425
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

30608:RRM2B
gene id: 30608:RRM2B
uniprot id: A0A8C5XM79
names: Cofactor
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.

30608:ATL1
gene id: 30608:ATL1
uniprot id: A0A8B7FVR3
uniprot id: A0A8B7X0Z8
uniprot id: A0A8B7X283
uniprot id: A0A8B7X2T0
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

30608:PLXNB3
gene id: 30608:PLXNB3
uniprot id: A0A8B7FUT5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:CHST12
gene id: 30608:CHST12
uniprot id: A0A8B7FZD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:BRPF3
gene id: 30608:BRPF3
uniprot id: A0A8B7F348
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105870401
gene id: 30608:LOC105870401
uniprot id: A0A8B7G8K3
names: Similarity
messages: Belongs to the intermediate filament family.

30608:CHEK1
gene id: 30608:CHEK1
uniprot id: A0A8B7X494
uniprot id: A0A8B7X5F5
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

30608:GPD1
gene id: 30608:GPD1
uniprot id: A0A8B7G5D3
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

30608:LOC105874395
gene id: 30608:LOC105874395
uniprot id: A0A8B7GSK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

30608:TNIP2
gene id: 30608:TNIP2
uniprot id: A0A8B7EED7
uniprot id: A0A8B7EEE2
uniprot id: A0A8B7EEZ8
uniprot id: A0A8B7EF40
names: Subcellular Location Annotation
messages: Cytoplasm

30608:LOC105860316
gene id: 30608:LOC105860316
uniprot id: A0A8B7EY74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ME3
gene id: 30608:ME3
uniprot id: A0A8B7X4W8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

30608:KCNB2
gene id: 30608:KCNB2
uniprot id: A0A8C5W334
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Perikaryon

30608:GNAO1
gene id: 30608:GNAO1
uniprot id: A0A8C5UNC8
uniprot id: A0A8C5YFF8
names: Similarity
messages: Belongs to the G-alpha family. G(i/o/t/z) subfamily.

30608:PPP6R2
gene id: 30608:PPP6R2
uniprot id: A0A8B7I4R9
uniprot id: A0A8B7I4S3
uniprot id: A0A8B7I5Q1
names: Similarity
messages: Belongs to the SAPS family.

30608:CAPRIN2
gene id: 30608:CAPRIN2
uniprot id: A0A8B7F6U8
uniprot id: A0A8B7WT95
uniprot id: A0A8B7WT98
uniprot id: A0A8B7WT99
uniprot id: A0A8B7WTA3
uniprot id: A0A8B7WTA4
uniprot id: A0A8B7WTA8
uniprot id: A0A8B7WTB2
uniprot id: A0A8B7WTF0
uniprot id: A0A8B7WTG1
uniprot id: A0A8B7WTG6
uniprot id: A0A8B7WTL6
uniprot id: A0A8B7WTM1
uniprot id: A0A8B7WTM6
uniprot id: A0A8B7WUV0
uniprot id: A0A8B7WUV9
uniprot id: A0A8B7WUW3
names: Similarity
messages: Belongs to the caprin family.

30608:HMX3
gene id: 30608:HMX3
uniprot id: A0A8C5UNG9
names: Subcellular Location Annotation
messages: Nucleus

30608:MIOS
gene id: 30608:MIOS
uniprot id: A0A8B7FTZ7
uniprot id: A0A8C5V9A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat mio family.
messages: Lysosome membrane

30608:PLPP3
gene id: 30608:PLPP3
uniprot id: A0A8B7XAH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

30608:GPR87
gene id: 30608:GPR87
uniprot id: A0A8B7HL99
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:PGM3
gene id: 30608:PGM3
uniprot id: A0A8B7GNX9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

30608:RNF112
gene id: 30608:RNF112
uniprot id: A0A8B7F6M4
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

30608:LOC105883401
gene id: 30608:LOC105883401
uniprot id: A0A8B7HV05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ANXA10
gene id: 30608:ANXA10
uniprot id: A0A8B7GS12
uniprot id: A0A8B7GSB4
uniprot id: A0A8B7WKS8
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

30608:TUBB
gene id: 30608:TUBB
uniprot id: A0A8B7EBT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

30608:LOC105875987
gene id: 30608:LOC105875987
uniprot id: A0A8B7H0Y3
names: Caution
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK. The mature dimeric form interacts with PPP1R16B (via its fourth ankyrin repeat). Interacts with PPP1CA only in the presence of PPP1R16B.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

30608:INTS13
gene id: 30608:INTS13
uniprot id: A0A8B7EJW8
uniprot id: A0A8B7EL47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the asunder family.
messages: Cytoplasm
messages: Nucleus

30608:REXO2
gene id: 30608:REXO2
uniprot id: A0A8C5W518
names: Similarity
messages: Belongs to the oligoribonuclease family.

30608:TNFRSF1A
gene id: 30608:TNFRSF1A
uniprot id: A0A8B7X7Z5
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:CAMK1D
gene id: 30608:CAMK1D
uniprot id: A0A8B7GEM7
uniprot id: A0A8B7GFH9
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:ANO3
gene id: 30608:ANO3
uniprot id: A0A8B7EXJ8
uniprot id: A0A8B7EXK2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:PTPRD
gene id: 30608:PTPRD
uniprot id: A0A8B7XAC3
uniprot id: A0A8B7XAC8
uniprot id: A0A8B7XAD4
uniprot id: A0A8B7XAD5
uniprot id: A0A8B7XAD8
uniprot id: A0A8B7XAE0
uniprot id: A0A8B7XAE1
uniprot id: A0A8B7XAE4
uniprot id: A0A8B7XAE6
uniprot id: A0A8B7XAE9
uniprot id: A0A8B7XAF1
uniprot id: A0A8B7XAF4
uniprot id: A0A8B7XAF5
uniprot id: A0A8B7XAF9
uniprot id: A0A8B7XAG0
uniprot id: A0A8B7XAG4
uniprot id: A0A8B7XAG6
uniprot id: A0A8B7XB49
uniprot id: A0A8B7XB55
uniprot id: A0A8B7XB60
uniprot id: A0A8B7XB65
uniprot id: A0A8B7XB70
uniprot id: A0A8B7XB75
uniprot id: A0A8B7XB80
uniprot id: A0A8B7XB85
uniprot id: A0A8B7XC21
uniprot id: A0A8B7XC25
uniprot id: A0A8B7XC29
uniprot id: A0A8B7XC34
uniprot id: A0A8B7XC39
uniprot id: A0A8B7XC45
uniprot id: A0A8B7XC51
uniprot id: A0A8B7XC56
uniprot id: A0A8B7XC61
uniprot id: A0A8B7XCI5
uniprot id: A0A8B7XCI9
uniprot id: A0A8B7XCJ4
uniprot id: A0A8B7XCJ9
uniprot id: A0A8B7XCK5
uniprot id: A0A8B7XCK9
uniprot id: A0A8B7XCL5
uniprot id: A0A8B7XCM0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

30608:CDC42SE2
gene id: 30608:CDC42SE2
uniprot id: A0A8B7G6G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Interacts with CDC42 (in GTP-bound form). Interacts weakly with RAC1 and not at all with RHOA.
messages: Membrane
messages: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
messages: cytoskeleton

30608:LOXL3
gene id: 30608:LOXL3
uniprot id: A0A8B7I0F2
uniprot id: A0A8B7I0F6
uniprot id: A0A8B7I371
uniprot id: A0A8C5V8Y2
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

30608:E2F2
gene id: 30608:E2F2
uniprot id: A0A8B7FDC3
uniprot id: A0A8B7FDE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

30608:TBX15
gene id: 30608:TBX15
uniprot id: A0A8B7G505
uniprot id: A0A8B7G522
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

30608:ATP11A
gene id: 30608:ATP11A
uniprot id: A0A8B7FG56
uniprot id: A0A8B7FGE2
uniprot id: A0A8B7FHC9
uniprot id: A0A8B7FHD4
uniprot id: A0A8C5UY68
uniprot id: A0A8C5XMJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

30608:LMNA
gene id: 30608:LMNA
uniprot id: A0A8B7GJW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Nucleus lamina

30608:LOC105879215
gene id: 30608:LOC105879215
uniprot id: A0A8B7HCZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105858728
gene id: 30608:LOC105858728
uniprot id: A0A8C5Y7E6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:LOC105881509
gene id: 30608:LOC105881509
uniprot id: A0A8B7GC07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

30608:LOC105883342
gene id: 30608:LOC105883342
uniprot id: A0A8B7HX08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:IMPDH1
gene id: 30608:IMPDH1
uniprot id: A0A8B7I1Q8
uniprot id: A0A8B7I1R3
uniprot id: A0A8B7I1R6
uniprot id: A0A8B7I3T4
uniprot id: A0A8B7I4L6
uniprot id: A0A8B7XBZ8
uniprot id: A0A8C5XAP9
uniprot id: A0A8C5XPU9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

30608:LOC105856694
gene id: 30608:LOC105856694
uniprot id: A0A8B7WXM6
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

30608:UBE2K
gene id: 30608:UBE2K
uniprot id: A0A8B7FL64
uniprot id: A0A8C5XMK5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:TAF8
gene id: 30608:TAF8
uniprot id: A0A8B7GYE3
uniprot id: A0A8B7GYG4
uniprot id: A0A8B7GYJ5
uniprot id: A0A8B7H0B0
uniprot id: A0A8C5VD23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

30608:LOC105881477
gene id: 30608:LOC105881477
uniprot id: A0A8B7HM12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMN family.
messages: Cajal body

30608:CHRD
gene id: 30608:CHRD
uniprot id: A0A8B7ED54
uniprot id: A0A8B7ED60
uniprot id: A0A8B7EDQ0
uniprot id: A0A8B7EDS8
uniprot id: A0A8B7EFS2
uniprot id: A0A8C5YF93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chordin family.
messages: Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.
messages: Secreted

30608:ALDH9A1
gene id: 30608:ALDH9A1
uniprot id: A0A8C5UUQ6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

30608:ZNF496
gene id: 30608:ZNF496
uniprot id: A0A8B7FHK2
names: Subcellular Location Annotation
messages: Nucleus

30608:CPLX2
gene id: 30608:CPLX2
uniprot id: A0A8B7HKR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

30608:VWC2
gene id: 30608:VWC2
uniprot id: A0A8B7EAV5
uniprot id: A0A8B7EB74
uniprot id: A0A8B7EDK9
uniprot id: A0A8B7XCI6
names: Subcellular Location Annotation
messages: Synapse

30608:KRT35
gene id: 30608:KRT35
uniprot id: A0A8C5V072
names: Similarity
messages: Belongs to the intermediate filament family.

30608:DPYSL3
gene id: 30608:DPYSL3
uniprot id: A0A8B7H0V3
uniprot id: A0A8C5XQF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Cytoplasm
messages: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
messages: growth cone

30608:APOD
gene id: 30608:APOD
uniprot id: A0A8C5YHH4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Homodimer.
messages: Secreted

30608:CHST7
gene id: 30608:CHST7
uniprot id: A0A8B7FBA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

30608:NOP2
gene id: 30608:NOP2
uniprot id: A0A8B7G1N0
uniprot id: A0A8B7G1N3
uniprot id: A0A8B7G2J8
uniprot id: A0A8B7G327
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: nucleolus

30608:CAPZA1
gene id: 30608:CAPZA1
uniprot id: A0A8B7HB28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

30608:PCLAF
gene id: 30608:PCLAF
uniprot id: A0A8B7FXE3
uniprot id: A0A8C5V1U7
names: Subcellular Location Annotation
messages: Nucleus
messages: perinuclear region

30608:TSC22D3
gene id: 30608:TSC22D3
uniprot id: A0A8B7FD88
uniprot id: A0A8B7FDH9
uniprot id: A0A8C5VM33
uniprot id: A0A8C6EIW1
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

30608:SDPR
gene id: 30608:SDPR
uniprot id: A0A8B7H791
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

30608:MPV17L
gene id: 30608:MPV17L
uniprot id: A0A8B7I751
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

30608:LOC105880857
gene id: 30608:LOC105880857
uniprot id: A0A8B7WTR9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

30608:AMPD3
gene id: 30608:AMPD3
uniprot id: A0A8B7FQL9
uniprot id: A0A8B7FQT4
uniprot id: A0A8B7FQU6
uniprot id: A0A8C5XZJ5
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Homotetramer.

30608:PNRC2
gene id: 30608:PNRC2
uniprot id: A0A8B7FD37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNRC family. PNRC2 subfamily.
messages: Nucleus
messages: P-body

30608:MMP10
gene id: 30608:MMP10
uniprot id: A0A8C5URN6
names: Similarity
messages: Belongs to the peptidase M10A family.

30608:LOC105863618
gene id: 30608:LOC105863618
uniprot id: A0A8B7FDR8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

30608:ARAF
gene id: 30608:ARAF
uniprot id: A0A8B7F7G7
uniprot id: A0A8B7F7H5
uniprot id: A0A8B7F7J0
uniprot id: A0A8C5XGH1
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

30608:LOC105864739
gene id: 30608:LOC105864739
uniprot id: A0A8B7FI91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TFCP2
gene id: 30608:TFCP2
uniprot id: A0A8B7G6M2
uniprot id: A0A8B7G7A2
uniprot id: A0A8B7G7T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

30608:CELF4
gene id: 30608:CELF4
uniprot id: A0A8B7FFU5
uniprot id: A0A8B7FFV0
uniprot id: A0A8B7FFV6
uniprot id: A0A8B7FFX4
uniprot id: A0A8B7FG30
uniprot id: A0A8B7FG35
uniprot id: A0A8B7FH05
uniprot id: A0A8B7WRF1
uniprot id: A0A8B7WRF6
uniprot id: A0A8B7WRG4
uniprot id: A0A8B7WRG8
uniprot id: A0A8B7WRI6
uniprot id: A0A8B7WRJ1
uniprot id: A0A8B7WSX0
uniprot id: A0A8C5USD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

30608:SRPX
gene id: 30608:SRPX
uniprot id: A0A8B7ECP1
uniprot id: A0A8C5VDR8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:TMED4
gene id: 30608:TMED4
uniprot id: A0A8B7G8R7
uniprot id: A0A8B7G8Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:WNK4
gene id: 30608:WNK4
uniprot id: A0A8B7EU29
uniprot id: A0A8B7EW23
uniprot id: A0A8C5VKD1
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

30608:C3H14orf166
gene id: 30608:C3H14orf166
uniprot id: A0A8B7FWT6
names: Similarity
messages: Belongs to the RTRAF family.

30608:TRPC6
gene id: 30608:TRPC6
uniprot id: A0A8B7GS71
uniprot id: A0A8B7GTJ6
uniprot id: A0A8B7X560
names: Subcellular Location Annotation
messages: Membrane

30608:RPS23
gene id: 30608:RPS23
uniprot id: A0A8B7HPT6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Component of the 40S small ribosomal subunit.
messages: Rough endoplasmic reticulum

30608:CACYBP
gene id: 30608:CACYBP
uniprot id: A0A8B7GD10
uniprot id: A0A8B7GDK2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
messages: Nucleus

30608:PANX1
gene id: 30608:PANX1
uniprot id: A0A8B7X3Y1
names: Caution
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: S-nitrosylation inhibits channel currents and ATP release.
messages: gap junction

30608:GANAB
gene id: 30608:GANAB
uniprot id: A0A8C6EKF9
uniprot id: A0A8C6EKX3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

30608:ROR2
gene id: 30608:ROR2
uniprot id: A0A8B7GZW4
uniprot id: A0A8B7XBC0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LOC105855641
gene id: 30608:LOC105855641
uniprot id: A0A8B7ECQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

30608:UTP18
gene id: 30608:UTP18
uniprot id: A0A8B7WMZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

30608:CCND3
gene id: 30608:CCND3
uniprot id: A0A8B7GYE6
uniprot id: A0A8B7GYK0
uniprot id: A0A8B7H0B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Nucleus

30608:IKBKE
gene id: 30608:IKBKE
uniprot id: A0A8B7WX35
uniprot id: A0A8B7WX37
uniprot id: A0A8B7WXF2
uniprot id: A0A8B7WYU4
names: Subcellular Location Annotation
messages: Cytoplasm

30608:DUSP10
gene id: 30608:DUSP10
uniprot id: A0A8B7EAN5
uniprot id: A0A8C5XQI4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

30608:COPS6
gene id: 30608:COPS6
uniprot id: A0A8B7FY76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN6 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.
messages: Cytoplasm
messages: Nucleus

30608:LOX
gene id: 30608:LOX
uniprot id: A0A8B7I0E3
uniprot id: A0A8B7I0E4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

30608:ARR3
gene id: 30608:ARR3
uniprot id: A0A8B7EBF8
names: Function
names: Similarity
messages: Belongs to the arrestin family.
messages: May play a role in an as yet undefined retina-specific signal transduction. Could bind to photoactivated-phosphorylated red/green opsins.

30608:LOC105872845
gene id: 30608:LOC105872845
uniprot id: A0A8B7FY98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

30608:ME1
gene id: 30608:ME1
uniprot id: A0A8B7GNP9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

30608:IZUMO2
gene id: 30608:IZUMO2
uniprot id: A0A8B7FLR6
uniprot id: A0A8C6EIN5
names: Similarity
messages: Belongs to the Izumo family.

30608:FRAT1
gene id: 30608:FRAT1
uniprot id: A0A8B7GJK9
names: Similarity
messages: Belongs to the GSK-3-binding protein family.

30608:B3GALNT1
gene id: 30608:B3GALNT1
uniprot id: A0A8B7X358
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:ARL1
gene id: 30608:ARL1
uniprot id: A0A8B7GX14
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

30608:LOC105883328
gene id: 30608:LOC105883328
uniprot id: A0A8B7HUT7
names: Subcellular Location Annotation
messages: Membrane

30608:DAXX
gene id: 30608:DAXX
uniprot id: A0A8C5VWK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAXX family.
messages: Cytoplasm
messages: PML body
messages: centromere
messages: nucleolus
messages: nucleoplasm

30608:PSMB11
gene id: 30608:PSMB11
uniprot id: A0A8B7FI82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

30608:APOLD1
gene id: 30608:APOLD1
uniprot id: A0A8B7H193
uniprot id: A0A8B7X625
uniprot id: A0A8B7X829
names: Similarity
messages: Belongs to the apolipoprotein L family.

30608:RPS17
gene id: 30608:RPS17
uniprot id: A0A8C5VQ92
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

30608:CDKN1C
gene id: 30608:CDKN1C
uniprot id: A0A8C5XGX7
names: Similarity
messages: Belongs to the CDI family.

30608:CHD7
gene id: 30608:CHD7
uniprot id: A0A8B7EI21
uniprot id: A0A8C5UN33
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

30608:SLC9A3R2
gene id: 30608:SLC9A3R2
uniprot id: A0A8B7EWQ8
uniprot id: A0A8B7EWR2
names: Function
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.

30608:GFM2
gene id: 30608:GFM2
uniprot id: A0A8B7XE61
uniprot id: A0A8B7XEP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

30608:KRT222
gene id: 30608:KRT222
uniprot id: A0A8B7GEZ1
uniprot id: A0A8C5W0A2
names: Similarity
messages: Belongs to the intermediate filament family.

30608:ABHD12
gene id: 30608:ABHD12
uniprot id: A0A8B7F208
uniprot id: A0A8C5UVH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serine esterase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:TJP2
gene id: 30608:TJP2
uniprot id: A0A8B7ED88
uniprot id: A0A8B7EDA0
uniprot id: A0A8B7EDQ3
uniprot id: A0A8B7EDS3
uniprot id: A0A8B7EDS5
uniprot id: A0A8C5VCV7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

30608:ANKRD13D
gene id: 30608:ANKRD13D
uniprot id: A0A8B7FV80
uniprot id: A0A8B7FW68
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

30608:LDHAL6B
gene id: 30608:LDHAL6B
uniprot id: A0A8B7FZT8
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

30608:NUP85
gene id: 30608:NUP85
uniprot id: A0A8B7HBP9
uniprot id: A0A8B7HBQ1
uniprot id: A0A8B7HBQ3
uniprot id: A0A8B7HBQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: nuclear pore complex

30608:RNPEP
gene id: 30608:RNPEP
uniprot id: A0A8B7EX09
uniprot id: A0A8B7WXV4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

30608:NFIC
gene id: 30608:NFIC
uniprot id: A0A8B7WXF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

30608:HCN3
gene id: 30608:HCN3
uniprot id: A0A8B7GK05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

30608:LGALS3
gene id: 30608:LGALS3
uniprot id: A0A8B7FWV7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Secreted

30608:LOC105868985
gene id: 30608:LOC105868985
uniprot id: A0A8B7G2X7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:GRM6
gene id: 30608:GRM6
uniprot id: A0A8B7I3T3
uniprot id: A0A8B7I3U5
uniprot id: A0A8B7I5T9
uniprot id: A0A8B7I6V3
uniprot id: A0A8B7WRE1
uniprot id: A0A8B7WRH6
uniprot id: A0A8C5VQU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

30608:EID1
gene id: 30608:EID1
uniprot id: A0A8B7G9T6
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105879981
gene id: 30608:LOC105879981
uniprot id: A0A8C5XJ34
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

30608:LCNL1
gene id: 30608:LCNL1
uniprot id: A0A8B7HQ54
uniprot id: A0A8B7HQ66
uniprot id: A0A8B7HQ67
uniprot id: A0A8B7HRZ0
uniprot id: A0A8B7HSK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

30608:EYA3
gene id: 30608:EYA3
uniprot id: A0A8B7FD13
uniprot id: A0A8C5XH64
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

30608:PDGFRB
gene id: 30608:PDGFRB
uniprot id: A0A8B7ERZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Interacts with homodimeric PDGFB and PDGFD, and with heterodimers formed by PDGFA and PDGFB.
messages: Lysosome lumen
messages: Membrane
messages: Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.
messages: Vesicle

30608:LOC105865518
gene id: 30608:LOC105865518
uniprot id: A0A8B7FLP5
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

30608:FAM92A
gene id: 30608:FAM92A
uniprot id: A0A8B7GXJ4
uniprot id: A0A8B7GXL3
uniprot id: A0A8B7GXP5
uniprot id: A0A8B7GZF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIBAR family.
messages: centriole
messages: cilium basal body

30608:CHIT1
gene id: 30608:CHIT1
uniprot id: A0A8B7FXM1
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

30608:POU5F1
gene id: 30608:POU5F1
uniprot id: A0A8C5UPT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-5 subfamily.
messages: Nucleus

30608:STEAP3
gene id: 30608:STEAP3
uniprot id: A0A8C5YEL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

30608:SENP2
gene id: 30608:SENP2
uniprot id: A0A8B7FAY4
uniprot id: A0A8B7FB30
uniprot id: A0A8B7FBJ5
names: Similarity
messages: Belongs to the peptidase C48 family.

30608:DIP2B
gene id: 30608:DIP2B
uniprot id: A0A8B7G5Q4
uniprot id: A0A8B7G5R8
uniprot id: A0A8B7G6I7
names: Similarity
messages: Belongs to the DIP2 family.

30608:LOC105876378
gene id: 30608:LOC105876378
uniprot id: A0A8B7WXY4
names: Similarity
messages: Belongs to the AF4 family.

30608:PAX3
gene id: 30608:PAX3
uniprot id: A0A8B7EQR8
uniprot id: A0A8B7ESH1
uniprot id: A0A8B7ESU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

30608:GALNT13
gene id: 30608:GALNT13
uniprot id: A0A8B7HEH6
uniprot id: A0A8B7HEJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

30608:MTHFR
gene id: 30608:MTHFR
uniprot id: A0A8B7HS77
uniprot id: A0A8B7HU83
uniprot id: A0A8B7HUH7
uniprot id: A0A8C5UPD0
uniprot id: A0A8C5YEU2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

30608:LOC105856645
gene id: 30608:LOC105856645
uniprot id: A0A8B7WSR5
names: Function
messages: Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

30608:NNT
gene id: 30608:NNT
uniprot id: A0A8B7ELX5
uniprot id: A0A8B7ELY1
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

30608:ASCC3
gene id: 30608:ASCC3
uniprot id: A0A8B7EI22
uniprot id: A0A8C5UVW3
names: Similarity
messages: Belongs to the helicase family.

30608:GSG1
gene id: 30608:GSG1
uniprot id: A0A8C5XUA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

30608:LOC105865490
gene id: 30608:LOC105865490
uniprot id: A0A8B7FLL1
names: Similarity
messages: Belongs to the histone H3 family.

30608:GALR1
gene id: 30608:GALR1
uniprot id: A0A8C5VJW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:GALNT15
gene id: 30608:GALNT15
uniprot id: A0A8B7GHV7
uniprot id: A0A8B7XAQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

30608:GDF9
gene id: 30608:GDF9
uniprot id: A0A8B7G5T8
uniprot id: A0A8B7G733
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: Secreted

30608:STN1
gene id: 30608:STN1
uniprot id: A0A8B7GS86
uniprot id: A0A8B7GTM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the STN1 family.
messages: Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
messages: Component of the CST complex.
messages: Nucleus
messages: telomere

30608:GLDC
gene id: 30608:GLDC
uniprot id: A0A8C5UIN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

30608:LOC109729980
gene id: 30608:LOC109729980
uniprot id: A0A8B7WVG3
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

30608:S100A6
gene id: 30608:S100A6
uniprot id: A0A8B7I733
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.
messages: Nucleus envelope

30608:C10H9orf3
gene id: 30608:C10H9orf3
uniprot id: A0A8B7F716
uniprot id: A0A8B7F721
uniprot id: A0A8B7F727
uniprot id: A0A8B7F744
uniprot id: A0A8C5UJG6
uniprot id: A0A8C6EJL5
names: Similarity
messages: Belongs to the peptidase M1 family.

30608:IL3RA
gene id: 30608:IL3RA
uniprot id: A0A8C5YDE4
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 5 subfamily.

30608:TESMIN
gene id: 30608:TESMIN
uniprot id: A0A8B7FV92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

30608:SCN11A
gene id: 30608:SCN11A
uniprot id: A0A8B7ETC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

30608:MED7
gene id: 30608:MED7
uniprot id: A0A8B7HKV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

30608:P2RY4
gene id: 30608:P2RY4
uniprot id: A0A8B7EE29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TREX1
gene id: 30608:TREX1
uniprot id: A0A8B7GV45
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

30608:ACTA2
gene id: 30608:ACTA2
uniprot id: A0A8C5XCE5
names: Similarity
messages: Belongs to the actin family.

30608:TUBD1
gene id: 30608:TUBD1
uniprot id: A0A8B7GTB6
uniprot id: A0A8B7GU77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Nucleus
messages: centriole
messages: cilium

30608:LOC105873892
gene id: 30608:LOC105873892
uniprot id: A0A8B7GNU1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:LOC105881316
gene id: 30608:LOC105881316
uniprot id: A0A8B7HNX7
names: Subcellular Location Annotation
messages: Membrane

30608:MBLAC1
gene id: 30608:MBLAC1
uniprot id: A0A8B7FY64
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

30608:ST6GALNAC3
gene id: 30608:ST6GALNAC3
uniprot id: A0A8B7HYP7
uniprot id: A0A8B7HYQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

30608:F5
gene id: 30608:F5
uniprot id: A0A8B7X1D4
names: Similarity
messages: Belongs to the multicopper oxidase family.

30608:LOC105868508
gene id: 30608:LOC105868508
uniprot id: A0A8B7G0C2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:NAPSA
gene id: 30608:NAPSA
uniprot id: A0A8B7FMY9
uniprot id: A0A8B7WU86
uniprot id: A0A8B7WVU9
names: Similarity
messages: Belongs to the peptidase A1 family.

30608:HAS2
gene id: 30608:HAS2
uniprot id: A0A8B7EUA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NodC/HAS family.
messages: Endoplasmic reticulum membrane
messages: Lysosome
messages: Membrane

30608:IER5
gene id: 30608:IER5
uniprot id: A0A8B7E9M4
names: Similarity
messages: Belongs to the IER family.

30608:VRK1
gene id: 30608:VRK1
uniprot id: A0A8B7I6D9
uniprot id: A0A8B7I6E4
uniprot id: A0A8B7I6E8
uniprot id: A0A8B7I6F3
uniprot id: A0A8B7I6I3
uniprot id: A0A8B7I8E0
uniprot id: A0A8B7X2A5
uniprot id: A0A8C5YBR4
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:ALX3
gene id: 30608:ALX3
uniprot id: A0A8B7FFC7
uniprot id: A0A8B7FGF7
names: Subcellular Location Annotation
messages: Nucleus

30608:MINDY4
gene id: 30608:MINDY4
uniprot id: A0A8B7EAK4
uniprot id: A0A8B7EAK9
uniprot id: A0A8B7EAN6
uniprot id: A0A8B7EAW7
uniprot id: A0A8B7EB92
uniprot id: A0A8B7EB97
uniprot id: A0A8B7EDB2
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

30608:KCNAB1
gene id: 30608:KCNAB1
uniprot id: A0A8C5YEZ2
uniprot id: A0A8C5YJ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

30608:LOC105884171
gene id: 30608:LOC105884171
uniprot id: A0A8B7HYM6
names: Subcellular Location Annotation
messages: Nucleus

30608:C21H12orf43
gene id: 30608:C21H12orf43
uniprot id: A0A8B7FSR1
uniprot id: A0A8C5XW42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUSTOS family.
messages: Nucleus envelope

30608:SLC6A9
gene id: 30608:SLC6A9
uniprot id: A0A8B7H4U3
uniprot id: A0A8B7H706
uniprot id: A0A8B7XC99
uniprot id: A0A8B7XCA2
uniprot id: A0A8B7XCA7
uniprot id: A0A8B7XCC4
uniprot id: A0A8B7XDF1
uniprot id: A0A8B7XE29
uniprot id: A0A8B7XEL3
uniprot id: A0A8C5W814
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily.
messages: Cell membrane
messages: Membrane

30608:NDUFA8
gene id: 30608:NDUFA8
uniprot id: A0A8B7GUV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

30608:ATP6V1D
gene id: 30608:ATP6V1D
uniprot id: A0A8B7X1D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: cilium
messages: clathrin-coated vesicle membrane

30608:KCNT2
gene id: 30608:KCNT2
uniprot id: A0A8B7EUD3
uniprot id: A0A8B7EUE6
uniprot id: A0A8B7EUF9
uniprot id: A0A8B7EUH4
uniprot id: A0A8B7EUH8
uniprot id: A0A8B7EUI0
uniprot id: A0A8B7EUR7
uniprot id: A0A8B7EWE2
uniprot id: A0A8B7EWF0
uniprot id: A0A8B7EWF4
uniprot id: A0A8B7EWJ0
uniprot id: A0A8B7EWL4
uniprot id: A0A8B7EWM4
uniprot id: A0A8B7EWN6
uniprot id: A0A8B7WX71
uniprot id: A0A8C5XX66
uniprot id: A0A8C5Y3F2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:UBE3D
gene id: 30608:UBE3D
uniprot id: A0A8C5US86
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

30608:ARGLU1
gene id: 30608:ARGLU1
uniprot id: A0A8B7FHH4
names: Similarity
messages: Belongs to the UPF0430 family.

30608:MAD1L1
gene id: 30608:MAD1L1
uniprot id: A0A8B7FY85
uniprot id: A0A8B7FY87
names: Similarity
messages: Belongs to the MAD1 family.

30608:ACOD1
gene id: 30608:ACOD1
uniprot id: A0A8B7EDN2
names: Similarity
messages: Belongs to the PrpD family.

30608:TEAD2
gene id: 30608:TEAD2
uniprot id: A0A8B7FM99
uniprot id: A0A8B7FMJ0
uniprot id: A0A8B7FMK4
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105884152
gene id: 30608:LOC105884152
uniprot id: A0A8B7HYK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105885075
gene id: 30608:LOC105885075
uniprot id: A0A8B7I301
names: Similarity
messages: Belongs to the Luc7 family.

30608:CTSC
gene id: 30608:CTSC
uniprot id: A0A8C5UR41
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Lysosome
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

30608:ACOT8
gene id: 30608:ACOT8
uniprot id: A0A8B7ET75
uniprot id: A0A8B7EV15
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

30608:LOC105881307
gene id: 30608:LOC105881307
uniprot id: A0A8B7HMP6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Monomer.

30608:LYZL4
gene id: 30608:LYZL4
uniprot id: A0A077S9K7
uniprot id: A0A8B7GRH1
uniprot id: A0A8B7WX20
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

30608:SPX
gene id: 30608:SPX
uniprot id: A0A8B7X7Q3
uniprot id: A0A8C5XHV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spexin family.
messages: Secreted

30608:MICALL2
gene id: 30608:MICALL2
uniprot id: A0A8B7FYY4
names: Subcellular Location Annotation
messages: Membrane

30608:DUSP8
gene id: 30608:DUSP8
uniprot id: A0A8B7GQX0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

30608:ATAD2
gene id: 30608:ATAD2
uniprot id: A0A8B7EU96
uniprot id: A0A8B7EW81
uniprot id: A0A8B7EW89
names: Similarity
messages: Belongs to the AAA ATPase family.

30608:LOC105866636
gene id: 30608:LOC105866636
uniprot id: A0A8B7WSJ3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:PSMD2
gene id: 30608:PSMD2
uniprot id: A0A8C5YIC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S2 family.
messages: Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

30608:MYH14
gene id: 30608:MYH14
uniprot id: A0A8B7WUY9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

30608:CASP10
gene id: 30608:CASP10
uniprot id: A0A8B7EIK6
names: Similarity
messages: Belongs to the peptidase C14A family.

30608:DBT
gene id: 30608:DBT
uniprot id: A0A8C5VBZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

30608:RUNX3
gene id: 30608:RUNX3
uniprot id: A0A8B7FDG3
uniprot id: A0A8B7FDP2
names: Function
names: Subcellular Location Annotation
messages: Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
messages: Nucleus

30608:MATK
gene id: 30608:MATK
uniprot id: A0A8B7GQ64
uniprot id: A0A8C5YGE1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

30608:C1GALT1
gene id: 30608:C1GALT1
uniprot id: A0A8B7FU00
uniprot id: A0A8B7FUV9
uniprot id: A0A8C5V5W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.
messages: Membrane

30608:TLCD1
gene id: 30608:TLCD1
uniprot id: A0A8B7ENY0
names: Subcellular Location Annotation
messages: Membrane

30608:FOXK1
gene id: 30608:FOXK1
uniprot id: A0A8B7FYK2
uniprot id: A0A8B7FYK6
uniprot id: A0A8B7FZK1
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105862891
gene id: 30608:LOC105862891
uniprot id: A0A8B7X1X5
names: Similarity
messages: Belongs to the peptidase S14 family.

30608:LOC105882039
gene id: 30608:LOC105882039
uniprot id: A0A8C6EKW8
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

30608:PKP4
gene id: 30608:PKP4
uniprot id: A0A8B7EZ17
uniprot id: A0A8B7EZ20
uniprot id: A0A8B7F0T5
uniprot id: A0A8B7F0U0
uniprot id: A0A8B7F183
uniprot id: A0A8B7F189
names: Similarity
messages: Belongs to the beta-catenin family.

30608:LOC105856671
gene id: 30608:LOC105856671
uniprot id: A0A8B7EHC0
uniprot id: A0A8B7EHR5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

30608:LOC105871709
gene id: 30608:LOC105871709
uniprot id: A0A8B7WSW7
uniprot id: A0A8B7WSX1
uniprot id: A0A8B7WT70
uniprot id: A0A8B7WUG5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

30608:POLR2G
gene id: 30608:POLR2G
uniprot id: A0A8B7HAC0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.
messages: Nucleus

30608:LOC105855890
gene id: 30608:LOC105855890
uniprot id: A0A8B7EGE8
names: Similarity
messages: Belongs to the SIN1 family.

30608:FOXN2
gene id: 30608:FOXN2
uniprot id: A0A8B7FR43
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105860521
gene id: 30608:LOC105860521
uniprot id: A0A8C5YHH1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:LPCAT4
gene id: 30608:LPCAT4
uniprot id: A0A8B7ET35
uniprot id: A0A8B7ET36
uniprot id: A0A8B7ET39
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

30608:CTSA
gene id: 30608:CTSA
uniprot id: A0A8C5VNE9
names: Similarity
messages: Belongs to the peptidase S10 family.

30608:LDLR
gene id: 30608:LDLR
uniprot id: A0A8B7WX57
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:ASTE1
gene id: 30608:ASTE1
uniprot id: A0A8B7GHR9
uniprot id: A0A8B7GIP4
names: Similarity
messages: Belongs to the asteroid family.

30608:PFN2
gene id: 30608:PFN2
uniprot id: A0A8B7HL79
uniprot id: A0A8B7HNP6
names: Function
names: Similarity
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

30608:NCOR1
gene id: 30608:NCOR1
uniprot id: A0A8B7EFN2
uniprot id: A0A8B7EFP0
uniprot id: A0A8B7EFP2
uniprot id: A0A8B7EG57
uniprot id: A0A8B7EG64
uniprot id: A0A8B7EGG9
uniprot id: A0A8B7EGH8
uniprot id: A0A8B7EGJ1
uniprot id: A0A8B7EI63
uniprot id: A0A8B7EI71
uniprot id: A0A8B7WN02
uniprot id: A0A8C5V8X0
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

30608:XPO1
gene id: 30608:XPO1
uniprot id: A0A8B7GCI1
uniprot id: A0A8B7GD53
uniprot id: A0A8C5VBV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm

30608:LOC109731122
gene id: 30608:LOC109731122
uniprot id: A0A8B7XBY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

30608:TNP1
gene id: 30608:TNP1
uniprot id: F7VJM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear transition protein 1 family.
messages: Nucleus

30608:DNTTIP1
gene id: 30608:DNTTIP1
uniprot id: A0A8B7ET76
uniprot id: A0A8B7WPX2
uniprot id: A0A8C5VBD1
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105875674
gene id: 30608:LOC105875674
uniprot id: A0A8B7WLM8
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:OTUD7A
gene id: 30608:OTUD7A
uniprot id: A0A8B7GCH2
uniprot id: A0A8B7GCX7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:ANXA4
gene id: 30608:ANXA4
uniprot id: A0A8B7FBN8
uniprot id: A0A8B7FCB8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Zymogen granule membrane

30608:NANOGNB
gene id: 30608:NANOGNB
uniprot id: A0A8B7H8U1
uniprot id: A0A8B7H8U5
names: Subcellular Location Annotation
messages: Nucleus

30608:RHOXF1
gene id: 30608:RHOXF1
uniprot id: A0A8B7EJ72
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105885239
gene id: 30608:LOC105885239
uniprot id: A0A8B7I5W0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:RPL5
gene id: 30608:RPL5
uniprot id: A0A8B7I658
uniprot id: A0A8B7WTU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

30608:SLC40A1
gene id: 30608:SLC40A1
uniprot id: A0A8B7H9I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

30608:AP4B1
gene id: 30608:AP4B1
uniprot id: A0A8B7HAX4
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

30608:FAM45A
gene id: 30608:FAM45A
uniprot id: A0A8B7EIX2
uniprot id: A0A8B7EIX3
uniprot id: A0A8B7EJ99
uniprot id: A0A8B7EK05
uniprot id: A0A8B7ELA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND10 family.
messages: Endosome
messages: Late endosome

30608:EVA1A
gene id: 30608:EVA1A
uniprot id: A0A8B7X2I7
names: Similarity
messages: Belongs to the EVA1 family.

30608:ZDHHC6
gene id: 30608:ZDHHC6
uniprot id: A0A8B7GWD0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

30608:ONECUT2
gene id: 30608:ONECUT2
uniprot id: A0A8B7EZM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

30608:SLC35A4
gene id: 30608:SLC35A4
uniprot id: A0A8B7F958
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

30608:KMT5C
gene id: 30608:KMT5C
uniprot id: A0A8B7H406
uniprot id: A0A8B7H686
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105860670
gene id: 30608:LOC105860670
uniprot id: A0A8B7WXH9
names: Similarity
messages: Belongs to the TGF-beta family.

30608:MAF1
gene id: 30608:MAF1
uniprot id: A0A8C5YEI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

30608:EFNA1
gene id: 30608:EFNA1
uniprot id: A0A8B7GKR2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:ACAT1
gene id: 30608:ACAT1
uniprot id: A0A8B7GZM0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

30608:NID1
gene id: 30608:NID1
uniprot id: A0A8B7EGS1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

30608:SERINC3
gene id: 30608:SERINC3
uniprot id: A0A8B7HGM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

30608:GJA4
gene id: 30608:GJA4
uniprot id: A0A8B7GDL8
uniprot id: A0A8B7GE52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

30608:LOC105864758
gene id: 30608:LOC105864758
uniprot id: A0A8B7FIE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:KCNA2
gene id: 30608:KCNA2
uniprot id: A0A8B7FFL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Presynaptic cell membrane
messages: Synaptic cell membrane
messages: lamellipodium membrane
messages: paranodal septate junction
messages: synaptosome

30608:LOC105871467
gene id: 30608:LOC105871467
uniprot id: A0A8B7GCC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

30608:ST3GAL4
gene id: 30608:ST3GAL4
uniprot id: A0A8B7GW63
uniprot id: A0A8B7GW78
uniprot id: A0A8B7GW83
uniprot id: A0A8B7GW84
uniprot id: A0A8B7GY01
uniprot id: A0A8B7GY08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

30608:CHST9
gene id: 30608:CHST9
uniprot id: A0A8B7WR00
uniprot id: A0A8B7WSC7
uniprot id: A0A8C5XY57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:RENBP
gene id: 30608:RENBP
uniprot id: A0A8B7FU70
uniprot id: A0A8B7FUV7
uniprot id: A0A8B7FV23
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

30608:WNT5B
gene id: 30608:WNT5B
uniprot id: A0A8B7F4R7
uniprot id: A0A8B7X8S5
uniprot id: A0A8B7X938
uniprot id: A0A8C5YCA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

30608:CHD2
gene id: 30608:CHD2
uniprot id: A0A8B7F876
names: Subcellular Location Annotation
messages: Nucleus

30608:CASD1
gene id: 30608:CASD1
uniprot id: A0A8B7FU05
uniprot id: A0A8B7FUN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PC-esterase family. CASD1 subfamily.
messages: Membrane

30608:PARP1
gene id: 30608:PARP1
uniprot id: A0A8B7FEM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARTD/PARP family.
messages: Chromosome
messages: Interacts (when auto-poly-ADP-ribosylated) with AIFM1.
messages: Nucleus
messages: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.
messages: This cleavage form irreversibly binds to DNA breaks and interferes with DNA repair, promoting DNA damage-induced apoptosis.

30608:TCTEX1D1
gene id: 30608:TCTEX1D1
uniprot id: A0A8B7GIE3
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

30608:BOD1
gene id: 30608:BOD1
uniprot id: A0A8C5XG61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BOD1 family.
messages: centrosome
messages: kinetochore

30608:LRRC8A
gene id: 30608:LRRC8A
uniprot id: A0A8B7GVU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

30608:YPEL5
gene id: 30608:YPEL5
uniprot id: A0A8B7I2J2
names: Similarity
messages: Belongs to the yippee family.

30608:LOC105864355
gene id: 30608:LOC105864355
uniprot id: A0A8B7FGU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cytoplasm

30608:SFT2D2
gene id: 30608:SFT2D2
uniprot id: A0A8B7HNN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

30608:DNAJC2
gene id: 30608:DNAJC2
uniprot id: A0A8B7F4E5
uniprot id: A0A8B7F4F6
uniprot id: A0A8B7F4G5
names: Function
names: Subcellular Location Annotation
messages: Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation.
messages: cytosol

30608:FTL
gene id: 30608:FTL
uniprot id: A0A8C5VFX1
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

30608:CPNE3
gene id: 30608:CPNE3
uniprot id: A0A8B7H0U3
names: Similarity
messages: Belongs to the copine family.

30608:SPTSSA
gene id: 30608:SPTSSA
uniprot id: A0A8C5YDK2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:LOC105859691
gene id: 30608:LOC105859691
uniprot id: A0A8B7WQY4
names: Similarity
messages: Belongs to the API5 family.

30608:MFSD7
gene id: 30608:MFSD7
uniprot id: A0A8B7HMK5
names: Subcellular Location Annotation
messages: Membrane

30608:STAC3
gene id: 30608:STAC3
uniprot id: A0A8B7H7K5
uniprot id: A0A8C5V1E8
names: Subcellular Location Annotation
messages: sarcolemma

30608:LOC109730255
gene id: 30608:LOC109730255
uniprot id: A0A8B7WZH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

30608:MCF2L
gene id: 30608:MCF2L
uniprot id: A0A8B7XE41
uniprot id: A0A8B7XE43
uniprot id: A0A8B7XE47
uniprot id: A0A8B7XE51
uniprot id: A0A8B7XE52
uniprot id: A0A8B7XFH2
uniprot id: A0A8B7XFH8
uniprot id: A0A8B7XFI8
uniprot id: A0A8B7XFW8
uniprot id: A0A8B7XFX0
uniprot id: A0A8B7XFX6
uniprot id: A0A8B7XGE5
uniprot id: A0A8C6EIA9
names: Subcellular Location Annotation
messages: Cytoplasm

30608:LOC105863187
gene id: 30608:LOC105863187
uniprot id: A0A8B7FBE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

30608:RAD18
gene id: 30608:RAD18
uniprot id: A0A8B7G278
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD18 family.
messages: Nucleus

30608:LOC105877660
gene id: 30608:LOC105877660
uniprot id: A0A8B7H640
uniprot id: A0A8B7WPW5
names: Subcellular Location Annotation
messages: Membrane

30608:HDDC2
gene id: 30608:HDDC2
uniprot id: A0A8B7H8M5
uniprot id: A0A8B7HB92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

30608:CLCN6
gene id: 30608:CLCN6
uniprot id: A0A8B7HS72
uniprot id: A0A8B7HS83
uniprot id: A0A8B7HU71
uniprot id: A0A8B7HUH2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:PIGC
gene id: 30608:PIGC
uniprot id: A0A8B7X019
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

30608:IL23A
gene id: 30608:IL23A
uniprot id: A0A8B7FM63
uniprot id: A0A8B7FM72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

30608:ADAMTS2
gene id: 30608:ADAMTS2
uniprot id: A0A8B7I3Q1
uniprot id: A0A8B7I3Q5
uniprot id: A0A8B7I5Q8
uniprot id: A0A8B7I6S4
uniprot id: A0A8B7I6T1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:POMT2
gene id: 30608:POMT2
uniprot id: A0A8B7ET52
uniprot id: A0A8B7EV04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

30608:LGI1
gene id: 30608:LGI1
uniprot id: A0A8C6EIJ8
names: Subcellular Location Annotation
messages: Secreted

30608:LOC105874563
gene id: 30608:LOC105874563
uniprot id: A0A8C5URP6
names: Similarity
messages: Belongs to the peptidase M10A family.

30608:DDX54
gene id: 30608:DDX54
uniprot id: A0A8B7FGY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
messages: nucleolus

30608:LOC105867933
gene id: 30608:LOC105867933
uniprot id: A0A8B7FWP9
uniprot id: A0A8B7WYA7
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:GPR52
gene id: 30608:GPR52
uniprot id: A0A8B7GDY5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:PTPRE
gene id: 30608:PTPRE
uniprot id: A0A8B7WM59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

30608:ADAM28
gene id: 30608:ADAM28
uniprot id: A0A8B7H0X0
uniprot id: A0A8B7WRY7
uniprot id: A0A8B7WRZ7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:PADI3
gene id: 30608:PADI3
uniprot id: A0A8B7G8U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

30608:MOG
gene id: 30608:MOG
uniprot id: A0A8B7EBR6
uniprot id: A0A8B7EEC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Homodimer.
messages: Membrane
messages: Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion.

30608:LOC105883435
gene id: 30608:LOC105883435
uniprot id: A0A8B7HV40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:AQP6
gene id: 30608:AQP6
uniprot id: A0A8B7G576
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

30608:LOC105876122
gene id: 30608:LOC105876122
uniprot id: A0A8B7GZN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

30608:ARRDC5
gene id: 30608:ARRDC5
uniprot id: A0A8B7GNJ4
names: Similarity
messages: Belongs to the arrestin family.

30608:CLDN1
gene id: 30608:CLDN1
uniprot id: A0A8C5YJB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

30608:LOC109731231
gene id: 30608:LOC109731231
uniprot id: A0A8B7XDK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MYCN
gene id: 30608:MYCN
uniprot id: A0A8B7X910
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

30608:ARRDC1
gene id: 30608:ARRDC1
uniprot id: A0A8B7HPX8
uniprot id: A0A8B7HPY2
uniprot id: A0A8B7HPY8
uniprot id: A0A8B7HPY9
uniprot id: A0A8B7HRQ3
uniprot id: A0A8B7HRQ8
uniprot id: A0A8B7HSC9
uniprot id: A0A8B7HSD3
names: Similarity
messages: Belongs to the arrestin family.

30608:GMFB
gene id: 30608:GMFB
uniprot id: A0A8B7FWW3
uniprot id: A0A8B7X2A9
uniprot id: A0A8C5VE73
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

30608:LIM2
gene id: 30608:LIM2
uniprot id: A0A8B7HSL1
uniprot id: A0A8B7HUM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis.

30608:ZGPAT
gene id: 30608:ZGPAT
uniprot id: A0A8B7GXT9
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CHD4/Mi-2; the interaction is direct.
messages: Nucleus

30608:CNNM3
gene id: 30608:CNNM3
uniprot id: A0A8B7HW96
uniprot id: A0A8B7HYP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

30608:ATG4D
gene id: 30608:ATG4D
uniprot id: A0A8C5UZZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

30608:LOC105857120
gene id: 30608:LOC105857120
uniprot id: A0A8B7WT23
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PKD1L2
gene id: 30608:PKD1L2
uniprot id: A0A8B7F3Q3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LOC105863646
gene id: 30608:LOC105863646
uniprot id: A0A8B7FDW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

30608:DHX15
gene id: 30608:DHX15
uniprot id: A0A8C5VAC8
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

30608:LOC105872945
gene id: 30608:LOC105872945
uniprot id: A0A8B7GIW3
names: Subcellular Location Annotation
messages: Membrane

30608:ZPR1
gene id: 30608:ZPR1
uniprot id: A0A8C5UM88
names: Similarity
messages: Belongs to the ZPR1 family.

30608:LOC105863897
gene id: 30608:LOC105863897
uniprot id: A0A8B7FF22
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:MPV17
gene id: 30608:MPV17
uniprot id: A0A8B7HZK3
uniprot id: A0A8B7HZK4
uniprot id: A0A8B7HZK6
uniprot id: A0A8B7I2A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

30608:ZNF287
gene id: 30608:ZNF287
uniprot id: A0A8C5XGF0
names: Subcellular Location Annotation
messages: Nucleus

30608:CCDC85B
gene id: 30608:CCDC85B
uniprot id: A0A8C5W654
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

30608:MED6
gene id: 30608:MED6
uniprot id: A0A8B7FS07
uniprot id: A0A8B7FSJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

30608:LOC105880744
gene id: 30608:LOC105880744
uniprot id: A0A8B7HKC3
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

30608:LOC105865684
gene id: 30608:LOC105865684
uniprot id: A0A8B7FMD7
uniprot id: A0A8B7FMJ5
uniprot id: A0A8B7FMK0
uniprot id: A0A8B7FMM7
uniprot id: A0A8B7FMP9
uniprot id: A0A8B7FNR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

30608:CCDC47
gene id: 30608:CCDC47
uniprot id: A0A8B7F4U6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Rough endoplasmic reticulum membrane

30608:NGLY1
gene id: 30608:NGLY1
uniprot id: A0A8B7HUG5
uniprot id: A0A8C5YF88
uniprot id: A0A8C5YI42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglutaminase-like superfamily. PNGase family.
messages: Cytoplasm
messages: Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins.

30608:CCNE2
gene id: 30608:CCNE2
uniprot id: A0A8B7GXH3
uniprot id: A0A8B7GXH7
uniprot id: A0A8B7XBW6
names: Similarity
messages: Belongs to the cyclin family. Cyclin E subfamily.

30608:CASTOR1
gene id: 30608:CASTOR1
uniprot id: A0A8B7GA11
uniprot id: A0A8C5XFN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GATS family.
messages: cytosol

30608:OAZ2
gene id: 30608:OAZ2
uniprot id: A0A8C5UT49
names: Similarity
messages: Belongs to the ODC antizyme family.

30608:GFOD2
gene id: 30608:GFOD2
uniprot id: A0A8B7ESB0
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

30608:WASHC1
gene id: 30608:WASHC1
uniprot id: A0A8C5W0K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WASH1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Recycling endosome membrane

30608:CD244
gene id: 30608:CD244
uniprot id: A0A8C5XEB7
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105883422
gene id: 30608:LOC105883422
uniprot id: A0A8B7HV21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PEX19
gene id: 30608:PEX19
uniprot id: A0A8B7F9D8
uniprot id: A0A8B7F9U7
uniprot id: A0A8C5VCE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxin-19 family.
messages: Interacts with a broad range of peroxisomal membrane proteins, including PEX3, PEX10, PEX11A, PEX11B, PEX12, PEX13, PEX14 and PEX16, PXMP2/PMP22, PXMP4/PMP24, SLC25A17/PMP34, ABCD1/ALDP, ABCD2/ALDRP, and ABCD3/PMP70. Also interacts with the tumor suppressor CDKN2A/p19ARF.
messages: Membrane
messages: Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.
messages: Peroxisome membrane

30608:LSM12
gene id: 30608:LSM12
uniprot id: A0A8C5W1B2
names: Similarity
messages: Belongs to the LSM12 family.

30608:MRPS9
gene id: 30608:MRPS9
uniprot id: A0A8B7EFV3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

30608:HS3ST3B1
gene id: 30608:HS3ST3B1
uniprot id: A0A8C5Y6Q4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:LOC105855558
gene id: 30608:LOC105855558
uniprot id: A0A8C5URW6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

30608:ASB1
gene id: 30608:ASB1
uniprot id: A0A8C5XN59
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

30608:SLC25A46
gene id: 30608:SLC25A46
uniprot id: A0A8B7FMY6
uniprot id: A0A8B7XD81
uniprot id: A0A8C5VV53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion outer membrane

30608:EIF2B4
gene id: 30608:EIF2B4
uniprot id: A0A8B7HZL5
uniprot id: A0A8B7I1P9
uniprot id: A0A8B7I2B7
uniprot id: A0A8C5V8J8
uniprot id: A0A8C5VAX5
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

30608:LOC105861301
gene id: 30608:LOC105861301
uniprot id: A0A8B7F2L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NRN1
gene id: 30608:NRN1
uniprot id: A0A8B7EG16
uniprot id: A0A8B7EHS9
names: Similarity
messages: Belongs to the neuritin family.

30608:CCR5
gene id: 30608:CCR5
uniprot id: A0A8B7GR92
uniprot id: A0A8B7GRH3
uniprot id: A0A8B7GSX0
uniprot id: A0A8C5YJA2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:MARVELD3
gene id: 30608:MARVELD3
uniprot id: A0A8B7EUI1
uniprot id: A0A8C5Y4K5
names: Subcellular Location Annotation
messages: Membrane

30608:SI
gene id: 30608:SI
uniprot id: A0A8B7HM55
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105885998
gene id: 30608:LOC105885998
uniprot id: A0A8B7I773
uniprot id: A0A8B7I7A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

30608:LOC105859376
gene id: 30608:LOC105859376
uniprot id: A0A8B7ETR9
uniprot id: A0A8B7EVR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

30608:LCLAT1
gene id: 30608:LCLAT1
uniprot id: A0A8B7HZU7
uniprot id: A0A8B7I1Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Endoplasmic reticulum membrane

30608:RCAN1
gene id: 30608:RCAN1
uniprot id: A0A8B7HLF0
uniprot id: A0A8B7HMQ7
uniprot id: A0A8B7WYU6
uniprot id: A0A8C5XW23
names: Similarity
messages: Belongs to the RCAN family.

30608:ELK1
gene id: 30608:ELK1
uniprot id: A0A8B7F7D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:ATP13A2
gene id: 30608:ATP13A2
uniprot id: A0A8B7WPC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

30608:LOC105861538
gene id: 30608:LOC105861538
uniprot id: A0A8B7F4E6
uniprot id: A0A8B7X646
uniprot id: A0A8B7X7U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

30608:ACVR2A
gene id: 30608:ACVR2A
uniprot id: A0A8C5UQR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

30608:LOC105860305
gene id: 30608:LOC105860305
uniprot id: A0A8B7F096
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105860131
gene id: 30608:LOC105860131
uniprot id: A0A8B7EXJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105879234
gene id: 30608:LOC105879234
uniprot id: A0A8B7HD05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105884118
gene id: 30608:LOC105884118
uniprot id: A0A8B7HYH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105861990
gene id: 30608:LOC105861990
uniprot id: A0A8B7WPP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

30608:ABHD3
gene id: 30608:ABHD3
uniprot id: A0A8C5WB66
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

30608:LOC105884150
gene id: 30608:LOC105884150
uniprot id: A0A8B7HYK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MAL2
gene id: 30608:MAL2
uniprot id: A0A8C5Y6D5
names: Subcellular Location Annotation
messages: Membrane

30608:MED12L
gene id: 30608:MED12L
uniprot id: A0A8B7HL82
uniprot id: A0A8B7HL90
uniprot id: A0A8B7HL91
uniprot id: A0A8B7HL93
uniprot id: A0A8B7HMI0
uniprot id: A0A8B7HMI6
uniprot id: A0A8B7HNQ5
uniprot id: A0A8B7HNR4
uniprot id: A0A8B7HNR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

30608:CPB2
gene id: 30608:CPB2
uniprot id: A0A8B7HKV9
names: Similarity
messages: Belongs to the peptidase M14 family.

30608:VPS33B
gene id: 30608:VPS33B
uniprot id: A0A8C5VFM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: clathrin-coated vesicle

30608:LOC105855780
gene id: 30608:LOC105855780
uniprot id: A0A8B7EFZ4
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:PSMD11
gene id: 30608:PSMD11
uniprot id: A0A8B7WPK0
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

30608:CHRNG
gene id: 30608:CHRNG
uniprot id: A0A8B7IB35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:UGP2
gene id: 30608:UGP2
uniprot id: A0A8B7GD65
uniprot id: A0A8C5VKB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

30608:PHKA1
gene id: 30608:PHKA1
uniprot id: A0A8B7HPS1
uniprot id: A0A8B7HPS3
uniprot id: A0A8C5XPN2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

30608:PGAP3
gene id: 30608:PGAP3
uniprot id: A0A8B7GFM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Golgi apparatus membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Membrane

30608:PDCD4
gene id: 30608:PDCD4
uniprot id: A0A8B7GVE5
names: Similarity
messages: Belongs to the PDCD4 family.

30608:ATP5F1
gene id: 30608:ATP5F1
uniprot id: A0A8B7FFN7
uniprot id: A0A8B7WX78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

30608:MCU
gene id: 30608:MCU
uniprot id: A0A8B7G6R0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

30608:TG
gene id: 30608:TG
uniprot id: A0A8B7HSH1
names: Caution
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PFKFB2
gene id: 30608:PFKFB2
uniprot id: A0A8B7G276
uniprot id: A0A8B7G283
uniprot id: A0A8B7G376
uniprot id: A0A8B7G3R1
uniprot id: A0A8B7WXU4
uniprot id: A0A8C5W1A4
uniprot id: A0A8C5Y6F3
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

30608:TTYH2
gene id: 30608:TTYH2
uniprot id: A0A8C5VW99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

30608:HCAR1
gene id: 30608:HCAR1
uniprot id: A0A8B7HJT7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:TGIF1
gene id: 30608:TGIF1
uniprot id: A0A8B7F1L4
uniprot id: A0A8B7F1L5
uniprot id: A0A8B7F3C3
uniprot id: A0A8B7F3P7
uniprot id: A0A8C5YCS0
names: Subcellular Location Annotation
messages: Nucleus

30608:SLC9A7
gene id: 30608:SLC9A7
uniprot id: A0A8B7FAU4
uniprot id: A0A8C5V668
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Endosome membrane
messages: Membrane

30608:LOC105872655
gene id: 30608:LOC105872655
uniprot id: A0A8B7GHJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted
messages: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.

30608:LOC105884134
gene id: 30608:LOC105884134
uniprot id: A0A8B7HYI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TEX261
gene id: 30608:TEX261
uniprot id: A0A8C5XFC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

30608:LRP1B
gene id: 30608:LRP1B
uniprot id: A0A8B7X8N1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:ESD
gene id: 30608:ESD
uniprot id: A0A8B7HKS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasmic vesicle
messages: Serine hydrolase involved in the detoxification of formaldehyde.

30608:GABRA6
gene id: 30608:GABRA6
uniprot id: A0A8C5VQR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:MAL
gene id: 30608:MAL
uniprot id: A0A8B7HW20
names: Subcellular Location Annotation
messages: Membrane

30608:PIK3C2G
gene id: 30608:PIK3C2G
uniprot id: A0A8B7HSL5
uniprot id: A0A8B7HUV5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

30608:PYM1
gene id: 30608:PYM1
uniprot id: A0A8B7FJ07
uniprot id: A0A8C5VD74
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pym family.
messages: Cytoplasm
messages: Interacts (via N-terminus) with magoh and rbm8a; the interaction is direct. Associates (eIF2A-like region) with the 40S ribosomal subunit and the 48S preinitiation complex.

30608:HK1
gene id: 30608:HK1
uniprot id: A0A8B7G724
uniprot id: A0A8C5V301
names: Similarity
messages: Belongs to the hexokinase family.

30608:SHQ1
gene id: 30608:SHQ1
uniprot id: A0A8C5W7M0
names: Similarity
messages: Belongs to the SHQ1 family.

30608:LOC105877040
gene id: 30608:LOC105877040
uniprot id: A0A8B7H5C2
names: Similarity
messages: Belongs to the CD225/Dispanin family.

30608:GCM1
gene id: 30608:GCM1
uniprot id: A0A8B7G429
names: Subcellular Location Annotation
messages: Nucleus

30608:ADK
gene id: 30608:ADK
uniprot id: A0A8B7G0E5
uniprot id: A0A8B7G191
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

30608:ISPD
gene id: 30608:ISPD
uniprot id: A0A8B7XDC2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Homodimer.
messages: cytosol

30608:MS4A2
gene id: 30608:MS4A2
uniprot id: A0A8B7FTP7
uniprot id: A0A8B7FUL1
names: Similarity
messages: Belongs to the MS4A family.

30608:SLC17A7
gene id: 30608:SLC17A7
uniprot id: A0A8C6EEA6
names: Subcellular Location Annotation
messages: Membrane

30608:POLR2C
gene id: 30608:POLR2C
uniprot id: A0A8C5Y5D8
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

30608:LOC105865727
gene id: 30608:LOC105865727
uniprot id: A0A8B7FMJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ICAM3
gene id: 30608:ICAM3
uniprot id: A0A8B7I5E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

30608:ABLIM2
gene id: 30608:ABLIM2
uniprot id: A0A8B7HMM0
uniprot id: A0A8B7HMM7
uniprot id: A0A8B7HMN0
uniprot id: A0A8B7HMN1
uniprot id: A0A8B7HMN2
uniprot id: A0A8B7HMN4
uniprot id: A0A8B7HMN7
uniprot id: A0A8B7HMP0
uniprot id: A0A8B7HMP3
uniprot id: A0A8B7HMP4
uniprot id: A0A8B7HMP5
uniprot id: A0A8B7HP53
uniprot id: A0A8B7HP60
uniprot id: A0A8B7HP65
uniprot id: A0A8B7HQ34
uniprot id: A0A8B7HQ45
uniprot id: A0A8B7HQ53
names: Subcellular Location Annotation
messages: Cytoplasm

30608:L3MBTL1
gene id: 30608:L3MBTL1
uniprot id: A0A8B7HH70
names: Subcellular Location Annotation
messages: Nucleus

30608:TXLNB
gene id: 30608:TXLNB
uniprot id: A0A8C5V5Y0
names: Similarity
messages: Belongs to the taxilin family.

30608:LOC105865617
gene id: 30608:LOC105865617
uniprot id: A0A8B7X7M4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:IGFBP6
gene id: 30608:IGFBP6
uniprot id: A0A8B7G8P5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:LOC105855778
gene id: 30608:LOC105855778
uniprot id: A0A8B7X2Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

30608:HGH1
gene id: 30608:HGH1
uniprot id: A0A8B7G290
names: Similarity
messages: Belongs to the HGH1 family.

30608:LOC105861075
gene id: 30608:LOC105861075
uniprot id: A0A8C5W8G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

30608:C10H9orf64
gene id: 30608:C10H9orf64
uniprot id: A0A8C5V8C3
names: Function
names: Similarity
messages: Belongs to the queuosine salvage protein family.
messages: Involved in salvaging queuosine.

30608:CHSY3
gene id: 30608:CHSY3
uniprot id: A0A8B7XF94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

30608:MTMR12
gene id: 30608:MTMR12
uniprot id: A0A8B7EH66
uniprot id: A0A8C5XKF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Sarcoplasmic reticulum
messages: sarcomere

30608:CCNB2
gene id: 30608:CCNB2
uniprot id: A0A8B7HLM2
names: Similarity
messages: Belongs to the cyclin family.

30608:CPEB4
gene id: 30608:CPEB4
uniprot id: A0A8B7GE61
uniprot id: A0A8B7GEN9
uniprot id: A0A8B7GEX4
uniprot id: A0A8B7GF27
names: Similarity
messages: Belongs to the RRM CPEB family.

30608:SLC24A1
gene id: 30608:SLC24A1
uniprot id: A0A8B7FXS6
uniprot id: A0A8B7FYK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

30608:LOC105862434
gene id: 30608:LOC105862434
uniprot id: A0A8B7F895
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC109730739
gene id: 30608:LOC109730739
uniprot id: A0A8B7X4K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:RPL36AL
gene id: 30608:RPL36AL
uniprot id: A0A8B7FWL8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

30608:WASF2
gene id: 30608:WASF2
uniprot id: A0A8B7FD70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

30608:TAF4B
gene id: 30608:TAF4B
uniprot id: A0A8B7EM20
uniprot id: A0A8B7EP99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

30608:LOC105869718
gene id: 30608:LOC105869718
uniprot id: A0A8B7G4U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:EIF4E2
gene id: 30608:EIF4E2
uniprot id: A0A8B7I7W5
uniprot id: A0A8C5V5J4
uniprot id: A0A8C5XUJ9
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

30608:PSMD12
gene id: 30608:PSMD12
uniprot id: A0A8B7F4X5
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

30608:L3HYPDH
gene id: 30608:L3HYPDH
uniprot id: A0A8B7X0Y4
uniprot id: A0A8C5UZX9
names: Similarity
messages: Belongs to the proline racemase family.

30608:MDM4
gene id: 30608:MDM4
uniprot id: A0A8B7FZZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.
messages: Nucleus

30608:SRP68
gene id: 30608:SRP68
uniprot id: A0A8C5VTX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

30608:TAF6
gene id: 30608:TAF6
uniprot id: A0A8B7FYA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

30608:PDP2
gene id: 30608:PDP2
uniprot id: A0A8B7EUL8
names: Similarity
messages: Belongs to the PP2C family.

30608:SLC35F1
gene id: 30608:SLC35F1
uniprot id: A0A8B7EIV6
uniprot id: A0A8B7EL93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

30608:LOC105872253
gene id: 30608:LOC105872253
uniprot id: A0A8B7WRT5
names: Similarity
messages: Belongs to the serpin family.

30608:ASB8
gene id: 30608:ASB8
uniprot id: A0A8B7FSA6
names: Function
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.
messages: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

30608:HAUS1
gene id: 30608:HAUS1
uniprot id: A0A8B7I6L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

30608:MAP3K11
gene id: 30608:MAP3K11
uniprot id: A0A8B7HA28
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

30608:RNASE11
gene id: 30608:RNASE11
uniprot id: W0UVC0
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

30608:ADGRE2
gene id: 30608:ADGRE2
uniprot id: A0A8B7WVG7
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LOC105864769
gene id: 30608:LOC105864769
uniprot id: A0A8B7FIF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:GNG2
gene id: 30608:GNG2
uniprot id: A0A8B7X2U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

30608:HSD3B2
gene id: 30608:HSD3B2
uniprot id: A0A8B7G519
uniprot id: A0A8B7G560
uniprot id: A0A8B7G6E4
names: Similarity
messages: Belongs to the 3-beta-HSD family.

30608:CRYBB2
gene id: 30608:CRYBB2
uniprot id: A0A8B7FSF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

30608:GLRA4
gene id: 30608:GLRA4
uniprot id: A0A8C5Y7Z2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

30608:CEP162
gene id: 30608:CEP162
uniprot id: A0A8B7GPT3
uniprot id: A0A8C5Y0C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP162 family.
messages: centriole

30608:LOC105880670
gene id: 30608:LOC105880670
uniprot id: A0A8B7HIY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

30608:LOC105881587
gene id: 30608:LOC105881587
uniprot id: A0A8B7HM86
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105881899
gene id: 30608:LOC105881899
uniprot id: A0A8B7WPL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

30608:MAGT1
gene id: 30608:MAGT1
uniprot id: A0A8B7WYN3
uniprot id: A0A8B7WYN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:THTPA
gene id: 30608:THTPA
uniprot id: A0A8B7FI51
uniprot id: A0A8B7FIC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Hydrolase highly specific for thiamine triphosphate (ThTP).
messages: Monomer.

30608:SERPINH1
gene id: 30608:SERPINH1
uniprot id: A0A8C5WBA7
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

30608:ADA2
gene id: 30608:ADA2
uniprot id: A0A8B7F623
uniprot id: A0A8B7X5H8
uniprot id: A0A8B7X639
uniprot id: A0A8B7X7H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

30608:LCA5L
gene id: 30608:LCA5L
uniprot id: A0A8B7WXX7
names: Similarity
messages: Belongs to the LCA5 family.

30608:KRT17
gene id: 30608:KRT17
uniprot id: A0A8B7GFL8
names: Similarity
messages: Belongs to the intermediate filament family.

30608:DDX47
gene id: 30608:DDX47
uniprot id: A0A8B7X6D5
names: Similarity
messages: Belongs to the DEAD box helicase family.

30608:PBRM1
gene id: 30608:PBRM1
uniprot id: A0A8B7GU83
uniprot id: A0A8B7GU88
uniprot id: A0A8B7GU91
uniprot id: A0A8B7GU93
uniprot id: A0A8B7GUD6
uniprot id: A0A8B7GUE1
uniprot id: A0A8B7GUF7
uniprot id: A0A8B7GUG1
uniprot id: A0A8B7GUH0
uniprot id: A0A8B7GW27
uniprot id: A0A8B7GW32
uniprot id: A0A8B7GW36
uniprot id: A0A8C5XLH9
names: Subcellular Location Annotation
messages: Nucleus

30608:MAP3K14
gene id: 30608:MAP3K14
uniprot id: A0A8C5VYQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cytoplasm
messages: Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity.

30608:TNFSF9
gene id: 30608:TNFSF9
uniprot id: A0A8B7G4S8
names: Similarity
messages: Belongs to the tumor necrosis factor family.

30608:ELAVL3
gene id: 30608:ELAVL3
uniprot id: A0A8B7WW31
uniprot id: A0A8B7WWT0
names: Similarity
messages: Belongs to the RRM elav family.

30608:KCNE1
gene id: 30608:KCNE1
uniprot id: A0A8B7F4D4
names: Similarity
messages: Belongs to the potassium channel KCNE family.

30608:NR4A2
gene id: 30608:NR4A2
uniprot id: A0A8B7ESP4
uniprot id: A0A8B7EUI3
uniprot id: A0A8B7X8I2
uniprot id: A0A8B7XA67
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Interacts with SFPQ, NCOR2, SIN3A and HADC1. The interaction with NCOR2 increases in the absence of PITX3. Interacts with PER2.
messages: Nucleus

30608:HSF1
gene id: 30608:HSF1
uniprot id: A0A8B7G166
uniprot id: A0A8B7X9X9
uniprot id: A0A8B7XAW9
uniprot id: A0A8C5V6D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

30608:PLCB1
gene id: 30608:PLCB1
uniprot id: A0A8B7WQF6
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

30608:LOC105869093
gene id: 30608:LOC105869093
uniprot id: A0A8B7G281
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Membrane

30608:SETD2
gene id: 30608:SETD2
uniprot id: A0A8B7GT35
uniprot id: A0A8C5VCP0
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

30608:KRT3
gene id: 30608:KRT3
uniprot id: A0A8B7G803
names: Similarity
messages: Belongs to the intermediate filament family.

30608:AKAP5
gene id: 30608:AKAP5
uniprot id: A0A8B7X1E3
names: Subcellular Location Annotation
messages: Membrane

30608:SERPINA11
gene id: 30608:SERPINA11
uniprot id: A0A8B7EI11
uniprot id: A0A8B7EIM0
names: Similarity
messages: Belongs to the serpin family.

30608:LBR
gene id: 30608:LBR
uniprot id: A0A8B7FER9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus inner membrane

30608:FGR
gene id: 30608:FGR
uniprot id: A0A8B7FDG5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

30608:PARD6A
gene id: 30608:PARD6A
uniprot id: A0A8B7ESA9
uniprot id: A0A8B7ESB5
uniprot id: A0A8B7EU45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cell membrane
messages: Cytoplasm
messages: tight junction

30608:BCL7A
gene id: 30608:BCL7A
uniprot id: A0A8B7WTV2
names: Similarity
messages: Belongs to the BCL7 family.

30608:LOC105865891
gene id: 30608:LOC105865891
uniprot id: A0A8B7FN90
names: Similarity
messages: Belongs to the ferlin family.

30608:LIPG
gene id: 30608:LIPG
uniprot id: A0A8C5XNX4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:CSF2
gene id: 30608:CSF2
uniprot id: A0A8B7WRG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GM-CSF family.
messages: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
messages: Monomer. The signaling GM-CSF receptor complex is a dodecamer of two head-to-head hexamers of two alpha, two beta, and two ligand subunits.
messages: Secreted

30608:IL24
gene id: 30608:IL24
uniprot id: A0A8B7G1Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

30608:CTPS1
gene id: 30608:CTPS1
uniprot id: A0A8B7EAM0
uniprot id: A0A8C5XX89
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

30608:ATP6V1G2
gene id: 30608:ATP6V1G2
uniprot id: A0A8B7ENQ0
uniprot id: A0A8B7X4P1
uniprot id: D0VXS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

30608:FEZ2
gene id: 30608:FEZ2
uniprot id: A0A8B7I017
uniprot id: A0A8B7I246
uniprot id: A0A8C5V9U0
names: Similarity
messages: Belongs to the zygin family.

30608:SBNO2
gene id: 30608:SBNO2
uniprot id: A0A8B7F0A5
uniprot id: A0A8B7F206
uniprot id: A0A8B7F2K7
uniprot id: A0A8C5V2C3
names: Similarity
messages: Belongs to the SBNO family.

30608:DNAH1
gene id: 30608:DNAH1
uniprot id: A0A8B7WL30
uniprot id: A0A8B7WL49
names: Similarity
messages: Belongs to the dynein heavy chain family.

30608:TRIP13
gene id: 30608:TRIP13
uniprot id: A0A8B7H0K8
uniprot id: A0A8C5XNK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AAA ATPase family. PCH2 subfamily.
messages: Nucleus
messages: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.
messages: Specifically interacts with the ligand binding domain of the thyroid receptor (TR). This interaction does not require the presence of thyroid hormone for its interaction. Interacts with proteasome subunit PSMA8; to participate in meiosis progression during spermatogenesis.

30608:ACTRT2
gene id: 30608:ACTRT2
uniprot id: A0A8B7H4G0
names: Similarity
messages: Belongs to the actin family.

30608:SNAP91
gene id: 30608:SNAP91
uniprot id: A0A8B7X4K5
uniprot id: A0A8B7X4L0
uniprot id: A0A8B7X4L5
uniprot id: A0A8B7X4M1
uniprot id: A0A8B7X568
uniprot id: A0A8B7X572
uniprot id: A0A8B7X6F7
uniprot id: A0A8B7X6G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PICALM/SNAP91 family.
messages: Membrane

30608:PROC
gene id: 30608:PROC
uniprot id: A0A8B7X9F7
uniprot id: A0A8B7XAD7
uniprot id: A0A8B7XAR7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:LOC105863122
gene id: 30608:LOC105863122
uniprot id: A0A8B7FB15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:UVSSA
gene id: 30608:UVSSA
uniprot id: A0A8B7HMF5
uniprot id: A0A8B7HMF8
uniprot id: A0A8B7HMF9
uniprot id: A0A8B7HMG0
uniprot id: A0A8B7HNW8
uniprot id: A0A8B7HPW7
names: Similarity
messages: Belongs to the UVSSA family.

30608:CNTNAP4
gene id: 30608:CNTNAP4
uniprot id: A0A8B7GWQ9
uniprot id: A0A8B7WUF7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:FKRP
gene id: 30608:FKRP
uniprot id: A0A8C5YAC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LicD transferase family.
messages: Golgi apparatus membrane

30608:LOC105885458
gene id: 30608:LOC105885458
uniprot id: A0A8B7I7T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105881934
gene id: 30608:LOC105881934
uniprot id: A0A8B7HNS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LEF1
gene id: 30608:LEF1
uniprot id: A0A8B7GG29
uniprot id: A0A8B7GGI6
uniprot id: A0A8B7WXT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

30608:NDUFB6
gene id: 30608:NDUFB6
uniprot id: A0A8B7GBW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB6 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

30608:MAT1A
gene id: 30608:MAT1A
uniprot id: A0A8B7G6T2
uniprot id: A0A8B7G7B9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

30608:MAPK9
gene id: 30608:MAPK9
uniprot id: A0A8B7FML5
uniprot id: A0A8B7FML9
uniprot id: A0A8B7FMZ7
uniprot id: A0A8B7FNZ3
uniprot id: A0A8C5XXV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

30608:ZNF280B
gene id: 30608:ZNF280B
uniprot id: A0A8B7G582
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus

30608:PYCR1
gene id: 30608:PYCR1
uniprot id: A0A8B7WPU3
uniprot id: A0A8C5V8A2
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

30608:LOC105865900
gene id: 30608:LOC105865900
uniprot id: A0A8B7FPM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PIH1D3
gene id: 30608:PIH1D3
uniprot id: A0A8B7FDU5
names: Similarity
messages: Belongs to the PIH1 family.

30608:CENPH
gene id: 30608:CENPH
uniprot id: A0A8B7HMS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-H/MCM16 family.
messages: Nucleus
messages: kinetochore

30608:CA1
gene id: 30608:CA1
uniprot id: A0A8B7XAF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Cytoplasm
messages: Reversible hydration of carbon dioxide.

30608:LOC105867925
gene id: 30608:LOC105867925
uniprot id: A0A8B7FXL3
uniprot id: A0A8B7FXN4
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:PPP1R1C
gene id: 30608:PPP1R1C
uniprot id: A0A8C5VKE8
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

30608:RBFOX3
gene id: 30608:RBFOX3
uniprot id: A0A8B7FRM4
uniprot id: A0A8B7FRQ4
uniprot id: A0A8B7FRQ5
uniprot id: A0A8B7FS70
uniprot id: A0A8B7FS83
uniprot id: A0A8B7FSP4
uniprot id: A0A8B7FSP9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

30608:SPIN1
gene id: 30608:SPIN1
uniprot id: A0A8B7EIA6
uniprot id: A0A8B7EJS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

30608:UIMC1
gene id: 30608:UIMC1
uniprot id: A0A8B7HX57
uniprot id: A0A8B7HX73
uniprot id: A0A8B7HZQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAP80 family.
messages: Nucleus

30608:KIF15
gene id: 30608:KIF15
uniprot id: A0A8B7GRC8
uniprot id: A0A8B7GT16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: spindle

30608:EP300
gene id: 30608:EP300
uniprot id: A0A8B7EQ96
names: Subcellular Location Annotation
messages: Cytoplasm

30608:SRD5A2
gene id: 30608:SRD5A2
uniprot id: A0A8B7HZW0
uniprot id: A0A8B7HZW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane
messages: Microsome membrane

30608:SHH
gene id: 30608:SHH
uniprot id: A0A8B7HWL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

30608:LOC105876954
gene id: 30608:LOC105876954
uniprot id: A0A8B7H2V5
uniprot id: A0A8B7H2V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

30608:PAPPA2
gene id: 30608:PAPPA2
uniprot id: A0A8B7GCW9
uniprot id: A0A8B7GCX1
uniprot id: A0A8B7GDG1
uniprot id: A0A8B7GDU7
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:FZD4
gene id: 30608:FZD4
uniprot id: A0A8B7F0M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

30608:SLC6A11
gene id: 30608:SLC6A11
uniprot id: A0A8B7HRY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

30608:B3GNT3
gene id: 30608:B3GNT3
uniprot id: A0A8B7WVR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:LOC105874767
gene id: 30608:LOC105874767
uniprot id: A0A8B7GSW4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

30608:LOC105879033
gene id: 30608:LOC105879033
uniprot id: A0A8B7HC79
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

30608:CREB3L4
gene id: 30608:CREB3L4
uniprot id: A0A8B7I6Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:MORF4L2
gene id: 30608:MORF4L2
uniprot id: A0A8B7I0Q5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the NuA4 histone acetyltransferase complex which contains the catalytic subunit KAT5/TIP60 and the subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A, MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41 and VPS72/YL1. The NuA4 complex interacts with MYC and the adenovirus E1A protein. MORF4L1 may also participate in the formation of NuA4 related complexes which lack the KAT5/TIP60 catalytic subunit, but which include the SWI/SNF related protein SRCAP. Component of the MSIN3A histone deacetylase complex, which includes SIN3A, HDAC2, ARID4B, MORF4L1, RBBP4/RbAp48, and RBBP7/RbAp46. Interacts with MRFAP1 and RB1. May also interact with one or more as yet undefined members of the TLE (transducin-like enhancer of split) family of transcriptional repressors.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also a component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
messages: Nucleus

30608:COPS7B
gene id: 30608:COPS7B
uniprot id: A0A8B7E9I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

30608:LOC105865869
gene id: 30608:LOC105865869
uniprot id: A0A8B7FN50
uniprot id: A0A8B7FNC4
uniprot id: A0A8C5W195
names: Similarity
messages: Belongs to the CBP3 family.

30608:DHDDS
gene id: 30608:DHDDS
uniprot id: A0A8B7FCV6
uniprot id: A0A8B7FCX1
uniprot id: A0A8B7FCX6
uniprot id: A0A8B7FDQ4
names: Similarity
messages: Belongs to the UPP synthase family.

30608:EDNRB
gene id: 30608:EDNRB
uniprot id: A0A8C5VA97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:DBX2
gene id: 30608:DBX2
uniprot id: A0A8C5VVN5
names: Subcellular Location Annotation
messages: Nucleus

30608:SEPT8
gene id: 30608:SEPT8
uniprot id: A0A8B7WRR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Presynapse
messages: synaptic vesicle membrane

30608:CWF19L1
gene id: 30608:CWF19L1
uniprot id: A0A8B7GLP0
uniprot id: A0A8B7GLP3
uniprot id: A0A8C5W0A4
names: Similarity
messages: Belongs to the CWF19 family.

30608:NUP210L
gene id: 30608:NUP210L
uniprot id: A0A8B7X209
names: Similarity
messages: Belongs to the NUP210 family.

30608:TLX3
gene id: 30608:TLX3
uniprot id: A0A8B7WVK1
uniprot id: A0A8C5XU18
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105882171
gene id: 30608:LOC105882171
uniprot id: A0A8B7HPP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

30608:SPTLC3
gene id: 30608:SPTLC3
uniprot id: A0A8C5UMA8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

30608:MRPL35
gene id: 30608:MRPL35
uniprot id: A0A8C5YAG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL35 family.
messages: Mitochondrion

30608:LOC105861484
gene id: 30608:LOC105861484
uniprot id: A0A8B7WLY7
names: Function
names: Similarity
messages: Belongs to the SPRN family.
messages: Prion-like protein that has PrP(C)-like neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP.

30608:CUL7
gene id: 30608:CUL7
uniprot id: A0A8B7GY75
uniprot id: A0A8B7GY79
uniprot id: A0A8B7GYC6
uniprot id: A0A8B7H041
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cullin family.
messages: Cytoplasm

30608:MYF6
gene id: 30608:MYF6
uniprot id: A0A8C5UNY9
names: Subcellular Location Annotation
messages: Nucleus

30608:SOX21
gene id: 30608:SOX21
uniprot id: A0A8B7GPV8
uniprot id: A0A8B7GQB0
names: Subcellular Location Annotation
messages: Nucleus

30608:ESCO2
gene id: 30608:ESCO2
uniprot id: A0A8C5XFC6
names: Subcellular Location Annotation
messages: Nucleus

30608:DEFB119
gene id: 30608:DEFB119
uniprot id: A0A8B7WRZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

30608:SCP2
gene id: 30608:SCP2
uniprot id: A0A8C5Y8M9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Cytoplasm
messages: Interacts with PEX5; the interaction is essential for peroxisomal import.
messages: Mitochondrion
messages: Peroxisome

30608:HHIP
gene id: 30608:HHIP
uniprot id: A0A8B7HNF1
uniprot id: A0A8B7HNF2
uniprot id: A0A8C5UQR4
names: Caution
names: Similarity
messages: Belongs to the HHIP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SLC8A3
gene id: 30608:SLC8A3
uniprot id: A0A8B7HHE4
uniprot id: A0A8B7HHE5
uniprot id: A0A8B7HHG9
uniprot id: A0A8B7HI84
uniprot id: A0A8B7HK10
uniprot id: A0A8C5V5L2
uniprot id: A0A8C5VDE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

30608:GCNT7
gene id: 30608:GCNT7
uniprot id: A0A8B7F835
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

30608:SMC2
gene id: 30608:SMC2
uniprot id: A0A8B7FKW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Chromosome
messages: Nucleus

30608:PRIM1
gene id: 30608:PRIM1
uniprot id: A0A8B7X5W1
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

30608:LOC105858693
gene id: 30608:LOC105858693
uniprot id: A0A8B7EQW5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:LOC105865610
gene id: 30608:LOC105865610
uniprot id: A0A8C5XU90
uniprot id: A0A8C5Y5J5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:AASS
gene id: 30608:AASS
uniprot id: A0A8B7XD05
names: Similarity
messages: In the C-terminal section; belongs to the saccharopine dehydrogenase family.
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

30608:POLR2H
gene id: 30608:POLR2H
uniprot id: A0A8B7EDV5
uniprot id: A0A8C5YG54
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

30608:LOC105878656
gene id: 30608:LOC105878656
uniprot id: A0A8B7HAQ9
names: Similarity
messages: Belongs to the peptidase A1 family.

30608:FAM174B
gene id: 30608:FAM174B
uniprot id: A0A8B7F883
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

30608:HSBP1
gene id: 30608:HSBP1
uniprot id: A0A8B7WSI7
names: Similarity
messages: Belongs to the HSBP1 family.

30608:BBOF1
gene id: 30608:BBOF1
uniprot id: A0A8B7EQC9
uniprot id: A0A8B7EQD7
uniprot id: A0A8B7EQH7
uniprot id: A0A8B7X2F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basal body protein required in multiciliate cells to align and maintain cilia orientation in response to flow. May act by mediating a maturation step that stabilizes and aligns cilia orientation. Not required to respond to planar cell polarity (PCP) or flow-based orientation cues.
messages: Belongs to the BBOF1 family.
messages: cilium basal body

30608:ATPAF2
gene id: 30608:ATPAF2
uniprot id: A0A8B7F6E0
uniprot id: A0A8B7F6F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

30608:ASIC2
gene id: 30608:ASIC2
uniprot id: A0A8B7I6U3
uniprot id: A0A8C5V0Q6
names: Subcellular Location Annotation
messages: Membrane

30608:INPPL1
gene id: 30608:INPPL1
uniprot id: A0A8C5XFZ5
names: Subcellular Location Annotation
messages: Basal cell membrane
messages: spindle pole

30608:LRP10
gene id: 30608:LRP10
uniprot id: A0A8C5UW71
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105865681
gene id: 30608:LOC105865681
uniprot id: A0A8B7FNQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MCHR2
gene id: 30608:MCHR2
uniprot id: A0A8C6EKQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC109730716
gene id: 30608:LOC109730716
uniprot id: A0A8B7X4G2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:GSK3A
gene id: 30608:GSK3A
uniprot id: A0A8B7FY44
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

30608:GRM4
gene id: 30608:GRM4
uniprot id: A0A8B7X4B9
uniprot id: A0A8B7X4X0
uniprot id: A0A8B7X630
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

30608:BLM
gene id: 30608:BLM
uniprot id: A0A8B7G8Q5
uniprot id: A0A8B7G8R0
uniprot id: A0A8B7G9N4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

30608:GDPD3
gene id: 30608:GDPD3
uniprot id: A0A8B7GC44
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

30608:LOC105883084
gene id: 30608:LOC105883084
uniprot id: A0A8B7HTP5
uniprot id: A0A8B7HTQ0
uniprot id: A0A8B7HTQ9
uniprot id: A0A8B7HVR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

30608:LOC105858726
gene id: 30608:LOC105858726
uniprot id: A0A8C5XZE5
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:PDE6B
gene id: 30608:PDE6B
uniprot id: A0A8C5V1R8
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

30608:LOC105870490
gene id: 30608:LOC105870490
uniprot id: A0A8B7G8D3
names: Similarity
messages: Belongs to the PRAME family.

30608:THPO
gene id: 30608:THPO
uniprot id: A0A8B7ED77
uniprot id: A0A8B7ED84
uniprot id: A0A8B7EDV0
uniprot id: A0A8B7EFU7
uniprot id: A0A8B7EFV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPO/TPO family.
messages: Secreted

30608:LOC105871362
gene id: 30608:LOC105871362
uniprot id: A0A8B7GD09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

30608:EXO5
gene id: 30608:EXO5
uniprot id: A0A8B7WKV0
names: Similarity
messages: Belongs to the EXO5 family.

30608:LYRM9
gene id: 30608:LYRM9
uniprot id: A0A8C5W187
names: Similarity
messages: Belongs to the complex I LYR family. LYRM9 subfamily.

30608:LOC105863120
gene id: 30608:LOC105863120
uniprot id: A0A8C5XAZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:DRD1
gene id: 30608:DRD1
uniprot id: A0A8B7HJ57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
messages: Membrane
messages: dendritic spine

30608:APP
gene id: 30608:APP
uniprot id: A0A8B7GBF1
uniprot id: A0A8B7GBF5
uniprot id: A0A8B7GBX9
uniprot id: A0A8B7GC11
uniprot id: A0A8B7GCF7
uniprot id: A0A8B7GCG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Cell membrane
messages: Cell surface
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Endoplasmic reticulum
messages: Endosome
messages: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis.
messages: Golgi apparatus
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).
messages: Nucleus
messages: Perikaryon
messages: Secreted
messages: The gamma-CTF peptides as well as the caspase-cleaved peptides, including C31, are potent enhancers of neuronal apoptosis.
messages: Vesicle
messages: clathrin-coated pit
messages: growth cone

30608:BRINP3
gene id: 30608:BRINP3
uniprot id: A0A8C5XWI5
names: Similarity
messages: Belongs to the BRINP family.

30608:RIMKLB
gene id: 30608:RIMKLB
uniprot id: A0A8B7H8S9
names: Similarity
messages: Belongs to the RimK family.

30608:SRPX2
gene id: 30608:SRPX2
uniprot id: A0A8B7GJZ7
names: Caution
names: Subcellular Location Annotation
messages: Cell surface
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Synapse

30608:MAP2
gene id: 30608:MAP2
uniprot id: A0A8B7FF31
uniprot id: A0A8B7X7R9
uniprot id: A0A8B7X7S3
uniprot id: A0A8B7X7S7
uniprot id: A0A8B7X7S8
uniprot id: A0A8B7X7T2
uniprot id: A0A8B7X7U0
uniprot id: A0A8B7X8F5
uniprot id: A0A8B7X8G0
uniprot id: A0A8B7X8G5
uniprot id: A0A8B7X9F9
uniprot id: A0A8B7X9G6
uniprot id: A0A8B7X9H1
uniprot id: A0A8B7X9H6
uniprot id: A0A8B7X9S1
uniprot id: A0A8B7X9S7
uniprot id: A0A8B7X9T2
uniprot id: A0A8B7X9T7
uniprot id: A0A8C5UWF0
uniprot id: A0A8C5XT76
names: Subcellular Location Annotation
messages: cytoskeleton

30608:HNF4G
gene id: 30608:HNF4G
uniprot id: A0A8C5VVK0
uniprot id: A0A8C5Y5B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

30608:FAM155B
gene id: 30608:FAM155B
uniprot id: A0A8C5XRA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NALF family.
messages: Membrane

30608:PM20D2
gene id: 30608:PM20D2
uniprot id: A0A8B7FDR5
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Catalyzes the peptide bond hydrolysis in dipeptides having basic amino acids lysine, ornithine or arginine at C-terminus.

30608:SLC12A9
gene id: 30608:SLC12A9
uniprot id: A0A8B7FZG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

30608:RPL12
gene id: 30608:RPL12
uniprot id: A0A8B7XD24
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

30608:SOAT1
gene id: 30608:SOAT1
uniprot id: A0A8B7GWU2
uniprot id: A0A8B7GWV8
uniprot id: A0A8B7GWW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:MBD4
gene id: 30608:MBD4
uniprot id: A0A8B7HS46
uniprot id: A0A8B7HS66
uniprot id: A0A8B7HU48
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with MLH1.
messages: Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.
messages: Nucleus

30608:LOC105863473
gene id: 30608:LOC105863473
uniprot id: A0A8B7FCV4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

30608:MAP2K1
gene id: 30608:MAP2K1
uniprot id: A0A8B7FX99
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:ACE
gene id: 30608:ACE
uniprot id: A0A8B7WME0
uniprot id: A0A8B7WME2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.

30608:FLI1
gene id: 30608:FLI1
uniprot id: A0A8B7GW82
uniprot id: A0A8B7GXX2
uniprot id: A0A8C5XU29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:HBE1
gene id: 30608:HBE1
uniprot id: A0A8C5Y6I5
names: Similarity
messages: Belongs to the globin family.

30608:CMTM7
gene id: 30608:CMTM7
uniprot id: A0A8B7WR92
names: Subcellular Location Annotation
messages: Membrane

30608:CCT8
gene id: 30608:CCT8
uniprot id: A0A8B7GC32
uniprot id: A0A8C5VP32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: cilium basal body

30608:SHC1
gene id: 30608:SHC1
uniprot id: A0A8B7GK94
uniprot id: A0A8B7GKK1
uniprot id: A0A8B7GKK6
uniprot id: A0A8B7GLE8
uniprot id: A0A8C5YEK4
names: Subcellular Location Annotation
messages: Cytoplasm

30608:LOC105874211
gene id: 30608:LOC105874211
uniprot id: A0A8B7XAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

30608:LOC105862510
gene id: 30608:LOC105862510
uniprot id: A0A8B7F8V8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

30608:FGFBP3
gene id: 30608:FGFBP3
uniprot id: A0A8B7GXZ1
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

30608:SNRPD2
gene id: 30608:SNRPD2
uniprot id: A0A8B7WUK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome.
messages: cytosol

30608:LOC105858301
gene id: 30608:LOC105858301
uniprot id: A0A8C5Y4W5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:MUM1L1
gene id: 30608:MUM1L1
uniprot id: A0A8B7HWZ1
names: Similarity
messages: Belongs to the PWWP3A family.

30608:GDPGP1
gene id: 30608:GDPGP1
uniprot id: A0A8B7XB06
uniprot id: A0A8B7XCE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDPGP1 family.
messages: Cytoplasm
messages: Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.

30608:POLR1C
gene id: 30608:POLR1C
uniprot id: A0A8B7GY32
uniprot id: A0A8B7GY81
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

30608:DPH2
gene id: 30608:DPH2
uniprot id: A0A8B7H701
uniprot id: A0A8C5UXP9
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

30608:LGI4
gene id: 30608:LGI4
uniprot id: A0A8B7H2R7
names: Subcellular Location Annotation
messages: Secreted

30608:ARMT1
gene id: 30608:ARMT1
uniprot id: A0A8B7EN92
uniprot id: A0A8C5XX99
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

30608:CTSK
gene id: 30608:CTSK
uniprot id: A0A8C5UTB3
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase C1 family.
messages: Cell membrane
messages: Lysosome
messages: Secreted

30608:LCN6
gene id: 30608:LCN6
uniprot id: A0A8B7HPX2
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

30608:GHRH
gene id: 30608:GHRH
uniprot id: A0A8B7FNZ6
uniprot id: A0A8B7WQN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

30608:THOC5
gene id: 30608:THOC5
uniprot id: A0A8B7G9W4
uniprot id: A0A8B7WUN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC5 family.
messages: Nucleus

30608:MRS2
gene id: 30608:MRS2
uniprot id: A0A8B7FKL4
uniprot id: A0A8C5XEM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

30608:SKI
gene id: 30608:SKI
uniprot id: A0A8B7WNI1
uniprot id: A0A8B7WNJ3
uniprot id: A0A8C5VES9
names: Similarity
messages: Belongs to the SKI family.

30608:TMEM134
gene id: 30608:TMEM134
uniprot id: A0A8C5VI87
uniprot id: A0A8C5YA28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Membrane

30608:SSH3
gene id: 30608:SSH3
uniprot id: A0A8B7FUW7
uniprot id: A0A8B7FVM2
uniprot id: A0A8B7FVR5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

30608:CLCF1
gene id: 30608:CLCF1
uniprot id: A0A8B7FUR2
uniprot id: A0A8B7FUX2
uniprot id: A0A8C5YAN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

30608:TREH
gene id: 30608:TREH
uniprot id: A0A8B7GZB8
uniprot id: A0A8C5XH34
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

30608:LOC105869714
gene id: 30608:LOC105869714
uniprot id: A0A8B7G5L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SLC44A4
gene id: 30608:SLC44A4
uniprot id: A0A8C5UNZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

30608:LOC105873371
gene id: 30608:LOC105873371
uniprot id: A0A8B7XCL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:C1D
gene id: 30608:C1D
uniprot id: A0A8B7FBV0
uniprot id: A0A8B7FBV4
uniprot id: A0A8B7FC05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the C1D family.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Nucleus
messages: Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
messages: nucleolus

30608:LOC105858336
gene id: 30608:LOC105858336
uniprot id: A0A8C5UXD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:FAM19A5
gene id: 30608:FAM19A5
uniprot id: A0A8B7X8L8
names: Similarity
messages: Belongs to the TAFA family.

30608:LOC105864452
gene id: 30608:LOC105864452
uniprot id: A0A8B7FH57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105874279
gene id: 30608:LOC105874279
uniprot id: A0A8B7GRU9
names: Similarity
messages: Belongs to the histone H2B family.

30608:LOC105875327
gene id: 30608:LOC105875327
uniprot id: A0A8C6EJ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CLPTM1L
gene id: 30608:CLPTM1L
uniprot id: A0A8B7H0J2
uniprot id: A0A8B7H0J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

30608:LOC109729189
gene id: 30608:LOC109729189
uniprot id: A0A8B7HTP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

30608:PPFIBP1
gene id: 30608:PPFIBP1
uniprot id: A0A8B7EJU4
uniprot id: A0A8B7EJU9
uniprot id: A0A8B7EJV3
uniprot id: A0A8B7EK58
uniprot id: A0A8B7EK65
uniprot id: A0A8B7EL23
uniprot id: A0A8B7EM75
uniprot id: A0A8B7EM80
uniprot id: A0A8C6ECN9
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

30608:NR1I3
gene id: 30608:NR1I3
uniprot id: A0A8B7GLX3
uniprot id: A0A8B7GN83
uniprot id: A0A8B7WY47
uniprot id: A0A8C5W1B9
uniprot id: A0A8C5XCK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

30608:PDCD5
gene id: 30608:PDCD5
uniprot id: A0A8B7H383
names: Similarity
messages: Belongs to the PDCD5 family.

30608:MOB2
gene id: 30608:MOB2
uniprot id: A0A8B7GPD7
uniprot id: A0A8B7GPE1
names: Similarity
messages: Belongs to the MOB1/phocein family.

30608:LOC105883368
gene id: 30608:LOC105883368
uniprot id: A0A8B7HX31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SGCD
gene id: 30608:SGCD
uniprot id: A0A8B7HIC0
uniprot id: A0A8B7HKW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

30608:USP26
gene id: 30608:USP26
uniprot id: A0A8B7GC89
uniprot id: A0A8B7GCS4
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

30608:TMSB10
gene id: 30608:TMSB10
uniprot id: A0A8B7HFB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

30608:MSH6
gene id: 30608:MSH6
uniprot id: A0A8B7FQ69
uniprot id: A0A8B7X8T8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

30608:SOD2
gene id: 30608:SOD2
uniprot id: A0A8C5VEZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homotetramer.
messages: Mitochondrion matrix

30608:TIMM10
gene id: 30608:TIMM10
uniprot id: A0A8B7FBI0
names: Function
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.

30608:GDA
gene id: 30608:GDA
uniprot id: A0A8B7GSW8
uniprot id: A0A8B7XCK2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

30608:FAM133A
gene id: 30608:FAM133A
uniprot id: A0A8B7FSZ7
names: Similarity
messages: Belongs to the FAM133 family.

30608:ACOXL
gene id: 30608:ACOXL
uniprot id: A0A8B7EST9
uniprot id: A0A8B7ESU1
uniprot id: A0A8B7ESU3
uniprot id: A0A8B7EUM8
uniprot id: A0A8B7EUN2
uniprot id: A0A8B7EUU5
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

30608:UNC5A
gene id: 30608:UNC5A
uniprot id: A0A8B7HX63
uniprot id: A0A8B7HX68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

30608:FAM131B
gene id: 30608:FAM131B
uniprot id: A0A8B7GKP4
uniprot id: A0A8B7GKP5
uniprot id: A0A8C5VPX2
names: Similarity
messages: Belongs to the FAM131 family.

30608:LOC105864461
gene id: 30608:LOC105864461
uniprot id: A0A8B7FH54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CDK14
gene id: 30608:CDK14
uniprot id: A0A8B7HGA5
uniprot id: A0A8C5UXE8
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:GPRC5D
gene id: 30608:GPRC5D
uniprot id: A0A8B7H1F3
uniprot id: A0A8C5YDG5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:CCNA2
gene id: 30608:CCNA2
uniprot id: A0A8B7HPE8
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

30608:LOC105855229
gene id: 30608:LOC105855229
uniprot id: A0A8B7EB80
uniprot id: A0A8B7EBH2
uniprot id: A0A8B7EDU9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

30608:MYO9A
gene id: 30608:MYO9A
uniprot id: A0A8B7GL55
uniprot id: A0A8B7GL59
uniprot id: A0A8B7GLH3
uniprot id: A0A8B7GLR4
uniprot id: A0A8B7GLR8
uniprot id: A0A8B7GME0
uniprot id: A0A8B7GME7
uniprot id: A0A8C5UL46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Cytoplasm
messages: Membrane
messages: Synapse
messages: growth cone

30608:LOC105884128
gene id: 30608:LOC105884128
uniprot id: A0A8B7HYI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ARL6
gene id: 30608:ARL6
uniprot id: A0A8B7GIL1
uniprot id: A0A8B7GIV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

30608:MTMR11
gene id: 30608:MTMR11
uniprot id: A0A8B7FLN6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

30608:LIPT1
gene id: 30608:LIPT1
uniprot id: A0A8B7HWF2
uniprot id: A0A8B7HYX0
names: Similarity
messages: Belongs to the LplA family.

30608:LOC105884254
gene id: 30608:LOC105884254
uniprot id: A0A8B7HYW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

30608:APOA4
gene id: 30608:APOA4
uniprot id: A0A8C5XBB5
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

30608:LOC105865724
gene id: 30608:LOC105865724
uniprot id: A0A8C5W588
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TENM4
gene id: 30608:TENM4
uniprot id: A0A8B7EX52
uniprot id: A0A8B7EX56
uniprot id: A0A8B7EX58
uniprot id: A0A8B7EX69
uniprot id: A0A8B7EX70
uniprot id: A0A8B7EX75
uniprot id: A0A8B7EX77
uniprot id: A0A8B7EZ21
uniprot id: A0A8B7EZ33
uniprot id: A0A8B7EZ60
uniprot id: A0A8B7X4J4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LOC105866180
gene id: 30608:LOC105866180
uniprot id: A0A8B7X2G3
names: Similarity
messages: Belongs to the serpin family.

30608:ZNRD1
gene id: 30608:ZNRD1
uniprot id: A0A8B7EBP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
messages: nucleolus

30608:CEBPZ
gene id: 30608:CEBPZ
uniprot id: A0A8B7I025
uniprot id: A0A8B7I032
uniprot id: A0A8C5UMN7
names: Similarity
messages: Belongs to the CBF/MAK21 family.

30608:MYO18B
gene id: 30608:MYO18B
uniprot id: A0A8B7FT11
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:C8G
gene id: 30608:C8G
uniprot id: A0A8B7HQ81
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

30608:LOC105865180
gene id: 30608:LOC105865180
uniprot id: A0A8B7FK42
uniprot id: A0A8B7FKC9
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

30608:INHA
gene id: 30608:INHA
uniprot id: A0A8B7ELL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.
messages: Secreted

30608:PITPNM3
gene id: 30608:PITPNM3
uniprot id: A0A8B7HF95
uniprot id: A0A8B7WNS7
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

30608:PTPRCAP
gene id: 30608:PTPRCAP
uniprot id: A0A8B7FUS7
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CD45/PTPRC.
messages: Membrane

30608:LOC105872194
gene id: 30608:LOC105872194
uniprot id: A0A8B7GFK0
names: Similarity
messages: Belongs to the intermediate filament family.

30608:SORCS1
gene id: 30608:SORCS1
uniprot id: A0A8B7GSG3
uniprot id: A0A8B7GSI7
uniprot id: A0A8B7GSR4
uniprot id: A0A8B7GU76
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

30608:ZDHHC22
gene id: 30608:ZDHHC22
uniprot id: A0A8B7ET24
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

30608:MTMR7
gene id: 30608:MTMR7
uniprot id: A0A8B7HRE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

30608:LOC105859768
gene id: 30608:LOC105859768
uniprot id: A0A8C5XP13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

30608:NPLOC4
gene id: 30608:NPLOC4
uniprot id: A0A8B7I2I6
names: Similarity
messages: Belongs to the NPL4 family.

30608:SLC11A1
gene id: 30608:SLC11A1
uniprot id: A0A8B7ELP9
uniprot id: A0A8B7ELQ3
uniprot id: A0A8B7ELZ6
uniprot id: A0A8B7EN35
uniprot id: A0A8B7ENZ2
names: Similarity
messages: Belongs to the NRAMP family.

30608:MCM7
gene id: 30608:MCM7
uniprot id: A0A8B7FZB2
uniprot id: A0A8C5VDZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

30608:LOC105885543
gene id: 30608:LOC105885543
uniprot id: A0A8B7WVP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:RPL28
gene id: 30608:RPL28
uniprot id: A0A8C5XTG9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL28 family.

30608:SYN1
gene id: 30608:SYN1
uniprot id: A0A8B7F7C3
uniprot id: A0A8B7F7H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synapsin family.
messages: Golgi apparatus
messages: Presynapse
messages: Synapse
messages: Vesicle
messages: synaptic vesicle

30608:APLP2
gene id: 30608:APLP2
uniprot id: A0A8B7HMC5
uniprot id: A0A8B7HMC7
uniprot id: A0A8C5W1Q4
uniprot id: A0A8C5XMI4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:SLC26A5
gene id: 30608:SLC26A5
uniprot id: A0A8B7F4D8
uniprot id: A0A8B7XC44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Cell membrane
messages: Membrane
messages: Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ.

30608:LOC105883372
gene id: 30608:LOC105883372
uniprot id: A0A8B7HX35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105870534
gene id: 30608:LOC105870534
uniprot id: A0A8B7XB96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:GPR108
gene id: 30608:GPR108
uniprot id: A0A8B7G5J6
uniprot id: A0A8B7G641
names: Subcellular Location Annotation
messages: Membrane

30608:EDEM3
gene id: 30608:EDEM3
uniprot id: A0A8B7EBC3
uniprot id: A0A8B7EBC6
uniprot id: A0A8B7EBP5
uniprot id: A0A8B7EBZ0
uniprot id: A0A8B7WXC0
uniprot id: A0A8B7WXS7
uniprot id: A0A8B7WYR1
uniprot id: A0A8C5VL60
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

30608:ZSCAN16
gene id: 30608:ZSCAN16
uniprot id: A0A8B7ET11
uniprot id: A0A8B7XE86
names: Subcellular Location Annotation
messages: Nucleus

30608:RC3H1
gene id: 30608:RC3H1
uniprot id: A0A8B7GD14
uniprot id: A0A8C5UNW2
names: Subcellular Location Annotation
messages: P-body

30608:NIF3L1
gene id: 30608:NIF3L1
uniprot id: A0A8B7EJ22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Cytoplasm
messages: Homodimer. Interacts with COPS2. Interacts with THOC7.
messages: May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
messages: Nucleus

30608:SPRY2
gene id: 30608:SPRY2
uniprot id: A0A8B7HT89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sprouty family.
messages: ruffle membrane

30608:LOC105880138
gene id: 30608:LOC105880138
uniprot id: A0A8B7HGX4
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

30608:KCNA4
gene id: 30608:KCNA4
uniprot id: A0A8B7FW75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: axon

30608:LOC105883357
gene id: 30608:LOC105883357
uniprot id: A0A8B7HX06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:KDM1A
gene id: 30608:KDM1A
uniprot id: A0A8B7WNY4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavin monoamine oxidase family.
messages: Histone demethylase that can demethylate both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3K4me on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity.
messages: Nucleus
messages: The SWIRM domain may act as an anchor site for a histone tail.

30608:NDUFA10
gene id: 30608:NDUFA10
uniprot id: A0A8C6ECH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA10 subunit family.
messages: Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction.
messages: Mitochondrion matrix

30608:PGLYRP2
gene id: 30608:PGLYRP2
uniprot id: A0A8C5V3V8
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

30608:MDGA1
gene id: 30608:MDGA1
uniprot id: A0A8B7F375
uniprot id: A0A8C5Y3U1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:DCLK2
gene id: 30608:DCLK2
uniprot id: A0A8B7HN86
uniprot id: A0A8B7HN90
uniprot id: A0A8B7HN91
uniprot id: A0A8B7HN94
uniprot id: A0A8B7HPU3
uniprot id: A0A8B7HQQ9
uniprot id: A0A8B7WKG2
uniprot id: A0A8B7WKG4
uniprot id: A0A8B7WL58
uniprot id: A0A8C6EKS8
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

30608:PRKAG1
gene id: 30608:PRKAG1
uniprot id: A0A8B7G3K5
uniprot id: A0A8B7G3L5
names: Similarity
names: Subunit
messages: AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or PRKAG3). Interacts with FNIP1 and FNIP2.
messages: Belongs to the 5'-AMP-activated protein kinase gamma subunit family.

30608:SLCO1B3
gene id: 30608:SLCO1B3
uniprot id: A0A8B7X6M2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LOC105856978
gene id: 30608:LOC105856978
uniprot id: A0A8B7EJ27
uniprot id: A0A8B7EL42
uniprot id: A0A8C5VB74
uniprot id: M1ZMS2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

30608:TMCO5A
gene id: 30608:TMCO5A
uniprot id: A0A8B7GGD2
uniprot id: A0A8B7GGD7
uniprot id: A0A8B7GGS8
uniprot id: A0A8B7GGT3
uniprot id: A0A8B7GH69
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105866564
gene id: 30608:LOC105866564
uniprot id: A0A8B7FR01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.
messages: Mitochondrion

30608:AFP
gene id: 30608:AFP
uniprot id: A0A8B7WWQ2
names: Subcellular Location Annotation
messages: Secreted

30608:LOC105858708
gene id: 30608:LOC105858708
uniprot id: A0A8B7ESP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105870582
gene id: 30608:LOC105870582
uniprot id: A0A8B7XAA0
uniprot id: A0A8B7XCF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

30608:SLC39A4
gene id: 30608:SLC39A4
uniprot id: A0A8B7G1D5
uniprot id: A0A8B7G2R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

30608:STOML2
gene id: 30608:STOML2
uniprot id: A0A8B7GS88
names: Similarity
messages: Belongs to the band 7/mec-2 family.

30608:LOC105858145
gene id: 30608:LOC105858145
uniprot id: A0A8B7ENL4
uniprot id: A0A8B7ENL7
uniprot id: A0A8B7ENS5
uniprot id: A0A8B7EQ61
uniprot id: A0A8B7EQS3
uniprot id: A0A8B7EQS7
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:PIGS
gene id: 30608:PIGS
uniprot id: A0A8C5VAQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:SIAH2
gene id: 30608:SIAH2
uniprot id: A0A8C5YHX0
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

30608:CPSF3
gene id: 30608:CPSF3
uniprot id: A0A8B7HT15
names: Subcellular Location Annotation
messages: Nucleus

30608:CD40LG
gene id: 30608:CD40LG
uniprot id: A0A8B7FS40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
messages: Belongs to the tumor necrosis factor family.
messages: Cell surface
messages: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
messages: Homotrimer.

30608:TOR1AIP1
gene id: 30608:TOR1AIP1
uniprot id: A0A8B7X045
uniprot id: A0A8B7X0N9
uniprot id: A0A8B7X187
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

30608:LOC105878361
gene id: 30608:LOC105878361
uniprot id: A0A8B7H959
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

30608:SMAD7
gene id: 30608:SMAD7
uniprot id: A0A8B7GRS9
uniprot id: A0A8C5XKX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

30608:TSPAN31
gene id: 30608:TSPAN31
uniprot id: A0A8C5W511
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

30608:LOC105885539
gene id: 30608:LOC105885539
uniprot id: A0A8B7I535
uniprot id: A0A8B7WW57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MRPL43
gene id: 30608:MRPL43
uniprot id: A0A8B7GNB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

30608:ANK1
gene id: 30608:ANK1
uniprot id: A0A8B7WSY3
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

30608:TMPRSS11D
gene id: 30608:TMPRSS11D
uniprot id: A0A8B7G4A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

30608:EIF2B5
gene id: 30608:EIF2B5
uniprot id: A0A8C5YK80
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

30608:HFE2
gene id: 30608:HFE2
uniprot id: A0A8C5VNW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

30608:STUM
gene id: 30608:STUM
uniprot id: A0A8B7FFS5
uniprot id: A0A8C5Y7F6
names: Subcellular Location Annotation
messages: Membrane

30608:SEC61B
gene id: 30608:SEC61B
uniprot id: A0A8B7GNI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

30608:LOC105876721
gene id: 30608:LOC105876721
uniprot id: A0A8B7H1C2
names: Similarity
messages: Belongs to the serpin family.

30608:GNRHR
gene id: 30608:GNRHR
uniprot id: A0A8B7G2W3
uniprot id: A0A8B7G3Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:HACD4
gene id: 30608:HACD4
uniprot id: A0A8B7XAW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:IMMP1L
gene id: 30608:IMMP1L
uniprot id: A0A8B7HTX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

30608:DUS3L
gene id: 30608:DUS3L
uniprot id: A0A8B7G4L3
uniprot id: A0A8C5VRY6
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.

30608:CACNA1E
gene id: 30608:CACNA1E
uniprot id: A0A8B7E9P5
uniprot id: A0A8B7E9U0
uniprot id: A0A8B7E9U2
uniprot id: A0A8B7E9V8
uniprot id: A0A8B7E9W7
uniprot id: A0A8B7E9X8
uniprot id: A0A8B7EA21
uniprot id: A0A8B7EAF1
uniprot id: A0A8B7EAG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents.

30608:GRAMD1B
gene id: 30608:GRAMD1B
uniprot id: A0A8B7I3G7
uniprot id: A0A8B7I3H2
uniprot id: A0A8B7I3H3
uniprot id: A0A8B7I3I0
uniprot id: A0A8B7I3I7
uniprot id: A0A8B7I5H3
uniprot id: A0A8B7I5I7
uniprot id: A0A8B7I6I9
uniprot id: A0A8B7I6K0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:ZSCAN10
gene id: 30608:ZSCAN10
uniprot id: A0A8B7EWW3
names: Subcellular Location Annotation
messages: Nucleus

30608:B2M
gene id: 30608:B2M
uniprot id: A0A8C5UUJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-2-microglobulin family.
messages: Secreted

30608:CTNND1
gene id: 30608:CTNND1
uniprot id: A0A8B7FB29
uniprot id: A0A8B7FB31
uniprot id: A0A8B7FB34
uniprot id: A0A8B7FB35
uniprot id: A0A8B7FB45
uniprot id: A0A8B7FB50
uniprot id: A0A8B7FB88
uniprot id: A0A8B7FB97
uniprot id: A0A8B7FBP8
uniprot id: A0A8B7FBQ3
uniprot id: A0A8B7FBR2
names: Similarity
messages: Belongs to the beta-catenin family.

30608:GMPR2
gene id: 30608:GMPR2
uniprot id: A0A8B7FR46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

30608:TTC3
gene id: 30608:TTC3
uniprot id: A0A8B7HML5
names: Subcellular Location Annotation
messages: Cytoplasm

30608:KRT71
gene id: 30608:KRT71
uniprot id: A0A8B7G856
names: Similarity
messages: Belongs to the intermediate filament family.

30608:CSN2
gene id: 30608:CSN2
uniprot id: A0A8B7HVS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-casein family.
messages: Important role in determination of the surface properties of the casein micelles.
messages: Secreted

30608:TMEM206
gene id: 30608:TMEM206
uniprot id: A0A8B7HIJ0
uniprot id: A0A8C5VRJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proton-activated chloride channel family.
messages: Cell membrane
messages: Membrane

30608:C3AR1
gene id: 30608:C3AR1
uniprot id: A0A8B7G254
uniprot id: A0A8B7G255
uniprot id: A0A8B7G3J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with VGF-derived peptide TLQP-21.
messages: Membrane
messages: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

30608:PPFIA3
gene id: 30608:PPFIA3
uniprot id: A0A8B7FM74
uniprot id: A0A8B7FNJ7
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

30608:MCHR1
gene id: 30608:MCHR1
uniprot id: A0A8C5Y0G3
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

30608:LOC105864755
gene id: 30608:LOC105864755
uniprot id: A0A8B7FID8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ADCK1
gene id: 30608:ADCK1
uniprot id: A0A8B7ETR3
uniprot id: A0A8B7EVT1
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

30608:ATP6V1G1
gene id: 30608:ATP6V1G1
uniprot id: A0A8B7GMZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

30608:SSH1
gene id: 30608:SSH1
uniprot id: A0A8B7FSL0
uniprot id: A0A8B7FT93
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

30608:NTNG1
gene id: 30608:NTNG1
uniprot id: A0A8B7FFJ0
uniprot id: A0A8B7FGE7
uniprot id: A0A8B7FGF2
uniprot id: A0A8B7WUI7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:TMEM63C
gene id: 30608:TMEM63C
uniprot id: A0A8B7EUS6
uniprot id: A0A8C5VZD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

30608:RTN4IP1
gene id: 30608:RTN4IP1
uniprot id: A0A8B7FJ48
uniprot id: A0A8B7FJ54
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

30608:CEP57L1
gene id: 30608:CEP57L1
uniprot id: A0A8B7FIZ5
uniprot id: A0A8B7FJ01
uniprot id: A0A8B7FJ22
uniprot id: A0A8B7FJ27
uniprot id: A0A8B7FJ68
names: Similarity
messages: Belongs to the translokin family.

30608:HNRNPAB
gene id: 30608:HNRNPAB
uniprot id: A0A8B7HXE8
uniprot id: A0A8C5VLT9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:LOC105866181
gene id: 30608:LOC105866181
uniprot id: A0A8B7X363
names: Similarity
messages: Belongs to the serpin family.

30608:LOC105861323
gene id: 30608:LOC105861323
uniprot id: A0A8B7F2P3
names: Subcellular Location Annotation
messages: Membrane

30608:SARAF
gene id: 30608:SARAF
uniprot id: A0A8B7HPA6
uniprot id: A0A8C5VPU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SARAF family.
messages: Endoplasmic reticulum membrane
messages: Interacts with STIM1; the interaction is inhibit by th interaction of STIM1 with EFHB.
messages: Membrane
messages: Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions.

30608:PNP
gene id: 30608:PNP
uniprot id: A0A8B7FIE6
uniprot id: A0A8B7FIM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

30608:LOC105856057
gene id: 30608:LOC105856057
uniprot id: A0A8C5VCZ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

30608:LOC105871381
gene id: 30608:LOC105871381
uniprot id: A0A8B7GC19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105884094
gene id: 30608:LOC105884094
uniprot id: A0A8B7X5Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TBX18
gene id: 30608:TBX18
uniprot id: A0A8B7FPT3
uniprot id: A0A8B7FQ03
uniprot id: A0A8B7FQB8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

30608:UTS2R
gene id: 30608:UTS2R
uniprot id: A0A8B7H857
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

30608:EMP1
gene id: 30608:EMP1
uniprot id: A0A8B7H1E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

30608:POLRMT
gene id: 30608:POLRMT
uniprot id: A0A8C5V554
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

30608:TSPAN19
gene id: 30608:TSPAN19
uniprot id: A0A8B7EN27
uniprot id: A0A8B7EN34
uniprot id: A0A8B7EPL1
uniprot id: A0A8B7EQA5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LIPE
gene id: 30608:LIPE
uniprot id: A0A8B7FX32
uniprot id: A0A8B7FX34
uniprot id: A0A8B7FXA1
uniprot id: A0A8B7FY25
uniprot id: A0A8B7FY55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'GDXG' lipolytic enzyme family.
messages: Cell membrane
messages: Lipid droplet
messages: caveola
messages: cytosol

30608:BCAS2
gene id: 30608:BCAS2
uniprot id: A0A8B7HAW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPF27 family.
messages: Nucleus

30608:LOC105862840
gene id: 30608:LOC105862840
uniprot id: A0A8B7FA27
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

30608:FOLR2
gene id: 30608:FOLR2
uniprot id: A0A8B7EY86
uniprot id: A0A8B7X4Z6
uniprot id: A0A8C5VSM0
names: Similarity
messages: Belongs to the folate receptor family.

30608:TACSTD2
gene id: 30608:TACSTD2
uniprot id: A0A8B7HTP9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:SLC4A11
gene id: 30608:SLC4A11
uniprot id: A0A8B7FN65
uniprot id: A0A8B7FN70
uniprot id: A0A8B7FNE4
uniprot id: A0A8B7FNK9
uniprot id: A0A8B7FPI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

30608:CSRNP1
gene id: 30608:CSRNP1
uniprot id: A0A8B7ET12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

30608:SLC9A3R1
gene id: 30608:SLC9A3R1
uniprot id: A0A8C5VFN0
names: Function
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.
messages: filopodium
messages: microvillus
messages: ruffle

30608:WDPCP
gene id: 30608:WDPCP
uniprot id: A0A8B7GCL9
uniprot id: A0A8B7GCM0
uniprot id: A0A8B7GD57
uniprot id: A0A8B7GD95
uniprot id: A0A8B7GDK6
uniprot id: A0A8B7X240
uniprot id: A0A8C5W9X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat fritz family.
messages: Cell membrane
messages: Membrane
messages: cilium axoneme

30608:LOC105873715
gene id: 30608:LOC105873715
uniprot id: A0A8B7GN81
uniprot id: A0A8B7GP13
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

30608:CHD9
gene id: 30608:CHD9
uniprot id: A0A8B7GX04
uniprot id: A0A8B7WSC6
uniprot id: A0A8B7WSD8
uniprot id: A0A8B7WSE1
uniprot id: A0A8B7WSE5
uniprot id: A0A8B7WSE6
uniprot id: A0A8B7WSF1
uniprot id: A0A8B7WSH3
uniprot id: A0A8B7WSJ1
uniprot id: A0A8B7WTW0
uniprot id: A0A8B7WTW5
uniprot id: A0A8B7WTX0
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

30608:TSPAN15
gene id: 30608:TSPAN15
uniprot id: A0A8B7G776
uniprot id: A0A8B7G7Q5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:SLC15A5
gene id: 30608:SLC15A5
uniprot id: A0A8C5UT19
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

30608:C5H11orf49
gene id: 30608:C5H11orf49
uniprot id: A0A8B7I282
uniprot id: A0A8B7I294
uniprot id: A0A8B7I299
uniprot id: A0A8B7I2A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSTPP1 family.
messages: centriolar satellite

30608:TMEM233
gene id: 30608:TMEM233
uniprot id: A0A8C5XFC7
names: Similarity
messages: Belongs to the CD225/Dispanin family.

30608:LOC105876159
gene id: 30608:LOC105876159
uniprot id: A0A8B7XC78
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:FAM129C
gene id: 30608:FAM129C
uniprot id: A0A8B7WVG2
names: Similarity
messages: Belongs to the Niban family.

30608:LOC105861436
gene id: 30608:LOC105861436
uniprot id: A0A8B7F498
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

30608:VAMP7
gene id: 30608:VAMP7
uniprot id: A0A8B7F438
uniprot id: A0A8B7F4A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

30608:LEO1
gene id: 30608:LEO1
uniprot id: A0A8B7G985
uniprot id: A0A8B7X1F0
names: Similarity
messages: Belongs to the LEO1 family.

30608:CACNA1A
gene id: 30608:CACNA1A
uniprot id: A0A8B7WVH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents.

30608:ANKH
gene id: 30608:ANKH
uniprot id: A0A8B7I4G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

30608:CPSF2
gene id: 30608:CPSF2
uniprot id: A0A8B7H015
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

30608:MTM1
gene id: 30608:MTM1
uniprot id: A0A8B7FJM3
uniprot id: A0A8B7FJN0
uniprot id: A0A8B7FL22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Late endosome
messages: filopodium
messages: ruffle
messages: sarcomere

30608:BCHE
gene id: 30608:BCHE
uniprot id: A0A8B7HPM8
uniprot id: A0A8C6ELL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

30608:NEIL1
gene id: 30608:NEIL1
uniprot id: A0A8B7E9L9
uniprot id: A0A8B7E9M9
uniprot id: A0A8B7E9R1
uniprot id: A0A8B7E9U8
uniprot id: A0A8B7EAB1
uniprot id: A0A8B7EAC1
names: Similarity
messages: Belongs to the FPG family.

30608:FAM207A
gene id: 30608:FAM207A
uniprot id: A0A8B7HEQ6
uniprot id: A0A8C5Y4E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLX9 family.
messages: nucleolus

30608:TAGLN2
gene id: 30608:TAGLN2
uniprot id: A0A8B7F9I6
names: Similarity
messages: Belongs to the calponin family.

30608:LOC105861877
gene id: 30608:LOC105861877
uniprot id: A0A8B7F632
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:ACAT2
gene id: 30608:ACAT2
uniprot id: A0A8B7G131
uniprot id: A0A8C5XCP2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

30608:EVC
gene id: 30608:EVC
uniprot id: A0A8B7WV22
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

30608:FAM172A
gene id: 30608:FAM172A
uniprot id: A0A8C5XH05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM172 family.
messages: Cytoplasm
messages: Nucleus

30608:VDAC2
gene id: 30608:VDAC2
uniprot id: A0A8B7FQ25
uniprot id: A0A8B7FQL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Mitochondrion outer membrane

30608:PRKRA
gene id: 30608:PRKRA
uniprot id: A0A8B7HVH0
uniprot id: A0A8B7X857
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRKRA family.
messages: perinuclear region

30608:LOC105884113
gene id: 30608:LOC105884113
uniprot id: A0A8B7X4C9
names: Subcellular Location Annotation
messages: Membrane

30608:SLC30A5
gene id: 30608:SLC30A5
uniprot id: A0A8B7HL86
uniprot id: A0A8B7HLA7
uniprot id: A0A8C5Y5X3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Homooligomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: trans-Golgi network membrane

30608:FGF8
gene id: 30608:FGF8
uniprot id: A0A8B7GNZ6
uniprot id: A0A8B7GP10
uniprot id: A0A8B7GPH7
uniprot id: A0A8C5VKC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

30608:TMEM63B
gene id: 30608:TMEM63B
uniprot id: A0A8B7EWE3
uniprot id: A0A8C5VJM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

30608:MAP7D2
gene id: 30608:MAP7D2
uniprot id: A0A8B7HQH2
uniprot id: A0A8B7HQH3
uniprot id: A0A8B7HQH4
uniprot id: A0A8B7HQH5
uniprot id: A0A8B7HQI0
uniprot id: A0A8B7HSA1
uniprot id: A0A8B7HSA6
uniprot id: A0A8B7HSB1
uniprot id: A0A8B7HSV5
uniprot id: A0A8B7HSW0
uniprot id: A0A8B7WYJ3
uniprot id: A0A8C5XU00
uniprot id: A0A8C5Y9R6
names: Similarity
messages: Belongs to the MAP7 family.

30608:KCNK2
gene id: 30608:KCNK2
uniprot id: A0A8B7HIP4
uniprot id: A0A8B7HIR2
uniprot id: A0A8C5W662
uniprot id: A0A8C5XP30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

30608:TAF1
gene id: 30608:TAF1
uniprot id: A0A8B7WYE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF1 family.
messages: Nucleus

30608:EIF3D
gene id: 30608:EIF3D
uniprot id: A0A8C5W464
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Cytoplasm
messages: Phosphorylated upon DNA damage, probably by ATM or ATR.
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. In the eIF-3 complex, EIF3D specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

30608:SF3A3
gene id: 30608:SF3A3
uniprot id: A0A8B7HGW5
names: Similarity
messages: Belongs to the SF3A3 family.

30608:AQP2
gene id: 30608:AQP2
uniprot id: A0A8B7G529
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

30608:GPHB5
gene id: 30608:GPHB5
uniprot id: A0A0F7RQH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

30608:TBCE
gene id: 30608:TBCE
uniprot id: A0A8B7EGQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

30608:NOL10
gene id: 30608:NOL10
uniprot id: A0A8C6EBI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

30608:VKORC1
gene id: 30608:VKORC1
uniprot id: A0A8C5VG12
uniprot id: A0A8C5Y408
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:MTFR2
gene id: 30608:MTFR2
uniprot id: A0A8B7EJQ6
uniprot id: A0A8B7EKY2
uniprot id: A0A8B7EM36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

30608:TP53RK
gene id: 30608:TP53RK
uniprot id: A0A8B7ETG5
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

30608:PKM
gene id: 30608:PKM
uniprot id: A0A8B7GL24
uniprot id: A0A8B7GL27
uniprot id: A0A8B7GLD9
uniprot id: A0A8B7GMA6
uniprot id: A0A8C5VCM8
names: Similarity
messages: Belongs to the pyruvate kinase family.

30608:TMEM258
gene id: 30608:TMEM258
uniprot id: A0A8B7HAI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

30608:ATP13A1
gene id: 30608:ATP13A1
uniprot id: A0A8B7EPF9
uniprot id: A0A8B7EPG7
uniprot id: A0A8C5XXX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

30608:PDGFD
gene id: 30608:PDGFD
uniprot id: A0A8B7GS33
uniprot id: A0A8B7GTF6
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Homodimer; disulfide-linked. Interacts with PDGFRB homodimers, and with heterodimers formed by PDGFRA and PDGFRB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:AMPD2
gene id: 30608:AMPD2
uniprot id: A0A8B7FFD1
uniprot id: A0A8C5UQ88
uniprot id: A0A8C5VLQ3
uniprot id: A0A8C5XNN9
uniprot id: A0A8C6EJ62
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Homotetramer.

30608:NUBP1
gene id: 30608:NUBP1
uniprot id: A0A8B7HRB2
uniprot id: A0A8B7HRC6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Cell projection
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. Interacts with KIFC1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:MYRFL
gene id: 30608:MYRFL
uniprot id: A0A8B7I0T7
uniprot id: A0A8B7I0T9
uniprot id: A0A8B7I2W7
uniprot id: A0A8B7X723
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRF family.
messages: Membrane

30608:MKI67
gene id: 30608:MKI67
uniprot id: A0A8B7WLB4
names: Subcellular Location Annotation
messages: Nucleus

30608:CLIC5
gene id: 30608:CLIC5
uniprot id: A0A8B7FS54
uniprot id: A0A8B7FST0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

30608:TWISTNB
gene id: 30608:TWISTNB
uniprot id: A0A8B7HH16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: nucleolus

30608:TRIM46
gene id: 30608:TRIM46
uniprot id: A0A8B7GK24
uniprot id: A0A8B7GK25
uniprot id: A0A8B7GKD7
uniprot id: A0A8B7GL85
names: Subcellular Location Annotation
messages: cytoskeleton

30608:LOC105863106
gene id: 30608:LOC105863106
uniprot id: A0A8B7FB60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Endoplasmic reticulum membrane

30608:RPP14
gene id: 30608:RPP14
uniprot id: A0A8B7I288
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

30608:EPO
gene id: 30608:EPO
uniprot id: A0A8C5UXW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPO/TPO family.
messages: Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.
messages: Secreted

30608:BTG1
gene id: 30608:BTG1
uniprot id: A0A8C5UVS7
names: Function
names: Similarity
messages: Anti-proliferative protein.
messages: Belongs to the BTG family.

30608:GBE1
gene id: 30608:GBE1
uniprot id: A0A8B7HSK6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

30608:MRPS30
gene id: 30608:MRPS30
uniprot id: A0A8C5UYB1
names: Subcellular Location Annotation
messages: Mitochondrion

30608:LOC105859236
gene id: 30608:LOC105859236
uniprot id: A0A8C5W0E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105883051
gene id: 30608:LOC105883051
uniprot id: A0A8B7WYH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

30608:PON3
gene id: 30608:PON3
uniprot id: A0A8B7FTR1
names: Cofactor
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.

30608:PURG
gene id: 30608:PURG
uniprot id: A0A8B7HQV2
uniprot id: A0A8B7HRL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

30608:PIK3CB
gene id: 30608:PIK3CB
uniprot id: A0A8B7F994
uniprot id: A0A8B7X2E8
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

30608:SMG8
gene id: 30608:SMG8
uniprot id: A0A8B7GKL3
names: Function
names: Similarity
messages: Belongs to the SMG8 family.
messages: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

30608:C17H1orf101
gene id: 30608:C17H1orf101
uniprot id: A0A8B7FEP9
uniprot id: A0A8B7FFN8
names: Similarity
messages: Belongs to the CATSPERD family.

30608:MRPL4
gene id: 30608:MRPL4
uniprot id: A0A8B7I5E9
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

30608:TGM2
gene id: 30608:TGM2
uniprot id: A0A8B7FPR4
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

30608:ASZ1
gene id: 30608:ASZ1
uniprot id: Q2QL84
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with DDX4, PIWIL1, RANBP9 and TDRD1.
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation (By similarity).

30608:LOC105859893
gene id: 30608:LOC105859893
uniprot id: A0A8B7EWB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:SLC46A2
gene id: 30608:SLC46A2
uniprot id: A0A8C5XB09
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105870544
gene id: 30608:LOC105870544
uniprot id: A0A8B7G9G4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:MYCBP2
gene id: 30608:MYCBP2
uniprot id: A0A8B7EDP2
uniprot id: A0A8B7EDP8
uniprot id: A0A8B7EDP9
uniprot id: A0A8B7EDQ7
uniprot id: A0A8B7EDR1
uniprot id: A0A8B7EEA6
uniprot id: A0A8B7EEB1
uniprot id: A0A8B7EEB2
uniprot id: A0A8B7EEB9
uniprot id: A0A8B7EEC1
uniprot id: A0A8B7EGA9
uniprot id: A0A8B7XF88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RING-Cys relay (RCR) family.
messages: axon

30608:PLTP
gene id: 30608:PLTP
uniprot id: A0A8B7EV57
names: Similarity
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

30608:CALCB
gene id: 30608:CALCB
uniprot id: A0A8B7HG75
names: Similarity
messages: Belongs to the calcitonin family.

30608:CDCP2
gene id: 30608:CDCP2
uniprot id: A0A8C6EIQ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:APRT
gene id: 30608:APRT
uniprot id: A0A8C5YH59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm

30608:LOC105855561
gene id: 30608:LOC105855561
uniprot id: A0A8B7ECL1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

30608:PCK1
gene id: 30608:PCK1
uniprot id: A0A8C5YBQ5
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

30608:CPEB1
gene id: 30608:CPEB1
uniprot id: A0A8B7G8F6
uniprot id: A0A8B7G8G0
uniprot id: A0A8B7G8M9
uniprot id: A0A8B7G944
uniprot id: A0A8B7G9K0
names: Similarity
messages: Belongs to the RRM CPEB family.

30608:DRC7
gene id: 30608:DRC7
uniprot id: A0A8B7EVT8
uniprot id: A0A8C5W0Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC7 family.
messages: cilium axoneme
messages: flagellum
messages: flagellum axoneme

30608:APOA1
gene id: 30608:APOA1
uniprot id: A0A8B7H1F8
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

30608:LOC105876619
gene id: 30608:LOC105876619
uniprot id: A0A8B7H116
uniprot id: A0A8B7H331
uniprot id: A0A8C5UST7
names: Similarity
messages: Belongs to the SNF7 family.

30608:PLD5
gene id: 30608:PLD5
uniprot id: A0A8B7FEJ9
uniprot id: A0A8B7FET7
uniprot id: A0A8C5UQ38
uniprot id: A0A8C5VN52
names: Similarity
messages: Belongs to the phospholipase D family.

30608:C3H15orf57
gene id: 30608:C3H15orf57
uniprot id: A0A8B7GGH5
uniprot id: A0A8B7GH84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL42 family.
messages: Mitochondrion

30608:DIO2
gene id: 30608:DIO2
uniprot id: A0A8B7X2H6
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

30608:ARPC4
gene id: 30608:ARPC4
uniprot id: A0A8C5VHP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

30608:KIAA1161
gene id: 30608:KIAA1161
uniprot id: A0A8B7GSF4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

30608:NDUFS5
gene id: 30608:NDUFS5
uniprot id: A0A8B7HER8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

30608:TSPYL4
gene id: 30608:TSPYL4
uniprot id: A0A8B7FJ43
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

30608:STK17A
gene id: 30608:STK17A
uniprot id: A0A8B7EPN4
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:PIANP
gene id: 30608:PIANP
uniprot id: A0A8B7G1R3
uniprot id: A0A8B7G1R4
names: Subcellular Location Annotation
messages: Membrane

30608:EIF4EBP1
gene id: 30608:EIF4EBP1
uniprot id: A0A8B7G811
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

30608:PKD1L3
gene id: 30608:PKD1L3
uniprot id: A0A8B7ETQ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:WNT10A
gene id: 30608:WNT10A
uniprot id: A0A8C6EI93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

30608:PHKA2
gene id: 30608:PHKA2
uniprot id: A0A8B7HQJ3
uniprot id: A0A8B7HQJ5
uniprot id: A0A8B7HQJ9
uniprot id: A0A8C5UTJ2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

30608:HHATL
gene id: 30608:HHATL
uniprot id: A0A8B7GRI8
uniprot id: A0A8B7GST1
names: Subcellular Location Annotation
messages: Membrane

30608:FAM46D
gene id: 30608:FAM46D
uniprot id: A0A8B7FPX4
names: Similarity
messages: Belongs to the TENT family.

30608:ADGRF2
gene id: 30608:ADGRF2
uniprot id: A0A8C5VNM0
names: Subcellular Location Annotation
messages: Membrane

30608:EIF3K
gene id: 30608:EIF3K
uniprot id: A0A8B7H1X6
uniprot id: A0A8C5V7K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit K family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with CCND3, but not with CCND1 and CCND2.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Nucleus

30608:NAGK
gene id: 30608:NAGK
uniprot id: A0A8B7FBS5
uniprot id: A0A8C5VZK4
uniprot id: A0A8C5Y536
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

30608:SLC25A16
gene id: 30608:SLC25A16
uniprot id: A0A8C5VQT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:LOC105867216
gene id: 30608:LOC105867216
uniprot id: A0A8B7FTK5
uniprot id: A0A8B7FTK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

30608:RPP30
gene id: 30608:RPP30
uniprot id: A0A8B7GEC8
uniprot id: A0A8C5V8J3
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

30608:OSBP
gene id: 30608:OSBP
uniprot id: A0A8B7G153
uniprot id: A0A8C5UNS7
names: Similarity
messages: Belongs to the OSBP family.

30608:DYNC1I2
gene id: 30608:DYNC1I2
uniprot id: A0A8B7HJ44
uniprot id: A0A8B7HJ45
uniprot id: A0A8B7HJ47
uniprot id: A0A8B7HK78
names: Similarity
messages: Belongs to the dynein intermediate chain family.

30608:FAM98B
gene id: 30608:FAM98B
uniprot id: A0A8B7X1F2
names: Similarity
messages: Belongs to the FAM98 family.

30608:LIG3
gene id: 30608:LIG3
uniprot id: A0A8B7I0H2
uniprot id: A0A8B7I112
uniprot id: A0A8C5VJE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

30608:GREM2
gene id: 30608:GREM2
uniprot id: A0A8C5YAT8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:HAMP
gene id: 30608:HAMP
uniprot id: A0A8B7H2X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

30608:GABRA4
gene id: 30608:GABRA4
uniprot id: A0A8C5V6L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:FAM118A
gene id: 30608:FAM118A
uniprot id: A0A8B7X6K9
names: Similarity
messages: Belongs to the FAM118 family.

30608:FGF18
gene id: 30608:FGF18
uniprot id: A0A8C5UZU5
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

30608:LOC105858527
gene id: 30608:LOC105858527
uniprot id: A0A8B7EQ47
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

30608:LOC105876119
gene id: 30608:LOC105876119
uniprot id: A0A8B7GZN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

30608:OPTN
gene id: 30608:OPTN
uniprot id: A0A8B7GEN1
uniprot id: A0A8B7WXZ2
uniprot id: A0A8C5XZ72
names: Function
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Endosome
messages: Golgi apparatus
messages: May act by regulating membrane trafficking and cellular morphogenesis.
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: perinuclear region
messages: trans-Golgi network

30608:TENM2
gene id: 30608:TENM2
uniprot id: A0A8B7HGY8
uniprot id: A0A8B7HGZ2
uniprot id: A0A8B7HHQ5
uniprot id: A0A8B7HJL4
uniprot id: A0A8B7WV53
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:HCRTR1
gene id: 30608:HCRTR1
uniprot id: A0A8B7XCX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MCMBP
gene id: 30608:MCMBP
uniprot id: A0A8B7EIZ0
uniprot id: A0A8B7EK33
uniprot id: A0A8B7ELC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCMBP family.
messages: Nucleus

30608:BUD23
gene id: 30608:BUD23
uniprot id: A0A8B7ERJ8
uniprot id: A0A8B7ETK7
uniprot id: A0A8C5V649
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

30608:RNF8
gene id: 30608:RNF8
uniprot id: A0A8B7F351
uniprot id: A0A8B7F357
uniprot id: A0A8B7F362
uniprot id: A0A8B7F417
uniprot id: A0A8C5XL73
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: According to a well-established model, RNF8 initiate H2A 'Lys-63'-linked ubiquitination leading to recruitment of RNF168 to amplify H2A 'Lys-63'-linked ubiquitination. However, other data suggest that RNF168 is the priming ubiquitin ligase by mediating monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub respectively). These data suggest that RNF168 might be recruited to DSBs sites in a RNF8-dependent manner by binding to non-histone proteins ubiquitinated via 'Lys-63'-linked and initiates monoubiquitination of H2A, which is then amplified by RNF8. Additional evidences are however required to confirm these data.
messages: Autoubiquitinated through 'Lys-48' and 'Lys-63' of ubiquitin. 'Lys-63' polyubiquitination is mediated by UBE2N. 'Lys-29'-type polyubiquitination is also observed, but it doesn't require its own functional RING-type zinc finger.
messages: Belongs to the CHFR family.
messages: Belongs to the RNF8 family.
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53BP1 and BRCA1 ionizing radiation-induced foci (IRIF). Also controls the recruitment of UIMC1-BRCC3 (RAP80-BRCC36) and PAXIP1/PTIP to DNA damage sites. Also recruited at DNA interstrand cross-links (ICLs) sites and catalyzes 'Lys-63'-linked ubiquitination of histones H2A and H2AX, leading to recruitment of FAAP20 and Fanconi anemia (FA) complex, followed by interstrand cross-link repair. H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Promotes the formation of 'Lys-63'-linked polyubiquitin chains via interactions with the specific ubiquitin-conjugating UBE2N/UBC13 and ubiquitinates non-histone substrates such as PCNA. Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation. Also catalyzes the formation of 'Lys-48'-linked polyubiquitin chains via interaction with the ubiquitin-conjugating UBE2L6/UBCH8, leading to degradation of substrate proteins such as CHEK2, JMJD2A/KDM4A and KU80/XRCC5: it is still unclear how the preference toward 'Lys-48'- versus 'Lys-63'-linked ubiquitination is regulated but it could be due to RNF8 ability to interact with specific E2 specific ligases. For instance, interaction with phosphorylated HERC2 promotes the association between RNF8 and UBE2N/UBC13 and favors the specific formation of 'Lys-63'-linked ubiquitin chains…
messages: Homodimer. Forms a E2-E3 ubiquitin ligase complex composed of the RNF8 homodimer and a E2 heterodimer of UBE2N and UBE2V2. Interacts with class III E2s, including UBE2E1, UBE2E2, and UBE2E3 and with UBE2N. Interacts with RXRA. Interacts (via FHA domain) with phosphorylated HERC2 (via C-terminus). Interacts with PIWIL1; leading to sequester RNF8 in the cytoplasm.
messages: Midbody
messages: Nucleus
messages: The FHA domain specifically recognizes and binds ATM-phosphorylated MDC1 and phosphorylated HERC2.
messages: telomere

30608:KHDRBS1
gene id: 30608:KHDRBS1
uniprot id: A0A8B7GDY7
names: Similarity
messages: Belongs to the KHDRBS family.

30608:LOC105866354
gene id: 30608:LOC105866354
uniprot id: A0A8B7FRA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative pheromone receptor.

30608:LOC105861495
gene id: 30608:LOC105861495
uniprot id: A0A8B7F4B0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with chaperones HSP70 and HSP90; this interaction is required for initial targeting to mitochondria.
messages: Microsome membrane
messages: Mitochondrion inner membrane
messages: The omega-1 hydroxylase activity is stimulated by cytochrome b5.

30608:GSDMB
gene id: 30608:GSDMB
uniprot id: A0A8B7GF40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

30608:PPM1E
gene id: 30608:PPM1E
uniprot id: A0A8B7GJQ9
names: Similarity
messages: Belongs to the PP2C family.

30608:FGF11
gene id: 30608:FGF11
uniprot id: A0A8B7H626
uniprot id: A0A8B7H635
uniprot id: A0A8B7H643
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

30608:HCK
gene id: 30608:HCK
uniprot id: A0A8B7FNV6
uniprot id: A0A8B7FP33
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

30608:ALDH6A1
gene id: 30608:ALDH6A1
uniprot id: A0A8B7EQB8
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

30608:LIN28A
gene id: 30608:LIN28A
uniprot id: A0A8C5VEE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-28 family.
messages: nucleolus

30608:IFI44
gene id: 30608:IFI44
uniprot id: A0A8B7HZP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI44 family.
messages: Cytoplasm

30608:P3H1
gene id: 30608:P3H1
uniprot id: A0A8C5VZG7
names: Similarity
messages: Belongs to the leprecan family.

30608:LOC105862432
gene id: 30608:LOC105862432
uniprot id: A0A8B7F8L1
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105866844
gene id: 30608:LOC105866844
uniprot id: A0A8B7WTH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-5A synthase family.
messages: Cytoplasm

30608:ICAM1
gene id: 30608:ICAM1
uniprot id: A0A8B7I7F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

30608:LOC105884106
gene id: 30608:LOC105884106
uniprot id: A0A8B7X3W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105870617
gene id: 30608:LOC105870617
uniprot id: A0A8B7G8N7
uniprot id: A0A8B7G9S8
uniprot id: A0A8B7G9T2
uniprot id: A0A8C5XJJ2
names: Similarity
messages: Belongs to the perilipin family.

30608:MVP
gene id: 30608:MVP
uniprot id: A0A8C5V3S7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.

30608:NLRP4
gene id: 30608:NLRP4
uniprot id: A0A8B7FA73
names: Similarity
messages: Belongs to the NLRP family.

30608:TMED7
gene id: 30608:TMED7
uniprot id: A0A8B7G9K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

30608:TMEM132D
gene id: 30608:TMEM132D
uniprot id: A0A8B7WU53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

30608:EIF4EBP2
gene id: 30608:EIF4EBP2
uniprot id: A0A8C5XUH7
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

30608:OPN5
gene id: 30608:OPN5
uniprot id: A0A8C5XVF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:LIN7B
gene id: 30608:LIN7B
uniprot id: A0A8B7FMG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the lin-7 family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.
messages: Postsynaptic density membrane
messages: tight junction

30608:LOC105861303
gene id: 30608:LOC105861303
uniprot id: A0A8B7F448
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:USP5
gene id: 30608:USP5
uniprot id: A0A8B7G1J5
uniprot id: A0A8B7G1K0
uniprot id: A0A8B7G2Y9
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

30608:BMP10
gene id: 30608:BMP10
uniprot id: A0A8B7FBM6
names: Similarity
messages: Belongs to the TGF-beta family.

30608:TEAD4
gene id: 30608:TEAD4
uniprot id: A0A8B7HM06
uniprot id: A0A8B7HNF5
uniprot id: A0A8B7HPI0
names: Subcellular Location Annotation
messages: Nucleus

30608:DEFB121
gene id: 30608:DEFB121
uniprot id: A0A8C5V2J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

30608:LOC105863849
gene id: 30608:LOC105863849
uniprot id: A0A8B7FEV3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

30608:PRKCI
gene id: 30608:PRKCI
uniprot id: A0A8C5YHB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

30608:LOC105864538
gene id: 30608:LOC105864538
uniprot id: A0A8B7FHG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC109730368
gene id: 30608:LOC109730368
uniprot id: A0A8B7X0K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

30608:TAS2R14
gene id: 30608:TAS2R14
uniprot id: A0A8B7F9J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

30608:CFL1
gene id: 30608:CFL1
uniprot id: A0A8B7HA77
uniprot id: A0A8C5VVE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family.
messages: lamellipodium membrane
messages: ruffle membrane

30608:TMEM201
gene id: 30608:TMEM201
uniprot id: A0A8B7I7B5
uniprot id: A0A8B7I9C9
uniprot id: A0A8B7I9D4
uniprot id: A0A8B7IAP1
uniprot id: A0A8B7WQ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM201 family.
messages: Membrane
messages: Nucleus inner membrane

30608:MARS2
gene id: 30608:MARS2
uniprot id: A0A8B7H9Y9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

30608:TRAF1
gene id: 30608:TRAF1
uniprot id: A0A8B7GUN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

30608:LOC105870410
gene id: 30608:LOC105870410
uniprot id: A0A8C5UM60
names: Similarity
messages: Belongs to the intermediate filament family.

30608:SBF2
gene id: 30608:SBF2
uniprot id: A0A8B7X3R4
uniprot id: A0A8B7X4P2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

30608:BRCA1
gene id: 30608:BRCA1
uniprot id: A0A8B7WN07
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Regulates centrosomal microtubule nucleation. Required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. Required for FANCD2 targeting to sites of DNA damage. Inhibits lipid synthesis by binding to inactive phosphorylated ACACA and preventing its dephosphorylation. Contributes to homologous recombination repair (HRR) via its direct interaction with PALB2, fine-tunes recombinational repair partly through its modulatory role in the PALB2-dependent loading of BRCA2-RAD51 repair machinery at DNA breaks. Component of the BRCA1-RBBP8 complex which regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage via BRCA1-mediated ubiquitination of RBBP8. Acts as a transcriptional activator.
messages: Heterodimer with BARD1. Part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the MRE11-RAD50-NBN protein (MRN) complex. This association could be a dynamic process changing throughout the cell cycle and within subnuclear domains. Component of the BRCA1-A complex, at least composed of BRCA1, BARD1, UIMC1/RAP80, ABRAXAS1, BRCC3/BRCC36, BABAM2 and BABAM1/NBA1. Interacts (via the BRCT domains) with ABRAXAS1 (phosphorylated form); this is important for recruitment to sites of DNA damage. Can form a heterotetramer with two molecules of ABRAXAS1 (phosphorylated form). Component of the BRCA1-RBBP8 complex. Interacts (via the BRCT domains) with RBBP8 ('Ser-327' phosphorylated form); the interaction ubiquitinates RBBP8, regulates CHEK1 activation, and involves RBBP8 in BRCA1-dependent G2/M checkpoint control on DNA damage. Associates with RNA polymerase II holoenzyme. Interacts with SMC1A, NELFB, DCLRE1C, CLSPN. CHEK1, CHEK2, BAP1, BRCC3, UBXN1 and PCLAF. Interacts (via BRCT domains) with BRIP1 (phosphorylated form). Interacts with FANCD2 (ubiquitinated form). Interacts with H2AX (phosphorylated on 'Ser-140'). Interacts (via the BRCT domains) with ACACA (phosphorylated form); the interaction prevents dephosphorylation of ACACA. Part of a BRCA complex containing BRCA1, BRCA2 and PALB2. Interacts directly with PALB2; the interaction is essential for its function in HRR. Interacts directly with BRCA2; the interaction occurs only in the presence of PALB2 which serves as the bridging protein. Interacts (via the BRCT domains) with LMO4; the interaction represses the transcriptional activity of BRCA1. Interacts (via the BRCT domains) with CCAR2 (via N-terminus); the interaction represses the transcriptional activator activity of BRCA1. Interacts with EXD2. Interacts (via C-terminus) with DHX9; this interaction is direct and links BRCA1 to the RNA polymerase II holoenzyme.
messages: Nucleus

30608:PPP1R15B
gene id: 30608:PPP1R15B
uniprot id: A0A8B7FZU6
names: Similarity
messages: Belongs to the PPP1R15 family.

30608:NEU4
gene id: 30608:NEU4
uniprot id: A0A8B7G7N1
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

30608:SLC6A1
gene id: 30608:SLC6A1
uniprot id: A0A8B7HRY7
uniprot id: A0A8C5UN70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

30608:ARTN
gene id: 30608:ARTN
uniprot id: A0A8B7H4P2
uniprot id: A0A8B7H4T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

30608:POFUT2
gene id: 30608:POFUT2
uniprot id: A0A8C5VYX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 68 family.
messages: Endoplasmic reticulum

30608:SMAD3
gene id: 30608:SMAD3
uniprot id: A0A8B7EQ44
uniprot id: A0A8C5YBL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

30608:FBN1
gene id: 30608:FBN1
uniprot id: A0A8B7X1Z7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:MYO16
gene id: 30608:MYO16
uniprot id: A0A8B7FG51
uniprot id: A0A8B7FG69
uniprot id: A0A8B7FHB8
uniprot id: A0A8B7FHC4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

30608:TAT
gene id: 30608:TAT
uniprot id: A0A8C5XB52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.

30608:LOC105864774
gene id: 30608:LOC105864774
uniprot id: A0A8B7FIG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:FCN2
gene id: 30608:FCN2
uniprot id: A0A8B7HJJ4
names: Similarity
messages: Belongs to the ficolin lectin family.

30608:TEX13A
gene id: 30608:TEX13A
uniprot id: A0A8B7HWY1
names: Similarity
messages: Belongs to the TEX13 family.

30608:HDAC9
gene id: 30608:HDAC9
uniprot id: A0A8B7HHT7
uniprot id: A0A8B7HJQ1
uniprot id: A0A8B7XCA4
uniprot id: A0A8B7XCA9
uniprot id: A0A8B7XCB4
uniprot id: A0A8B7XCB6
uniprot id: A0A8B7XCB9
uniprot id: A0A8B7XDC7
uniprot id: A0A8B7XDD9
uniprot id: A0A8B7XDE6
uniprot id: A0A8B7XE04
uniprot id: A0A8B7XE19
uniprot id: A0A8B7XEJ5
uniprot id: A0A8B7XEK0
uniprot id: A0A8B7XEK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus

30608:SNX18
gene id: 30608:SNX18
uniprot id: A0A8B7FSX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

30608:GLT6D1
gene id: 30608:GLT6D1
uniprot id: A0A8B7HJH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

30608:LOC105883627
gene id: 30608:LOC105883627
uniprot id: A0A8B7HW40
uniprot id: A0A8B7HW42
uniprot id: A0A8B7HYH1
names: Similarity
messages: Belongs to the FAH family.

30608:ASL
gene id: 30608:ASL
uniprot id: A0A8C5VL50
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

30608:TNN
gene id: 30608:TNN
uniprot id: A0A8B7GCZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

30608:TRMT11
gene id: 30608:TRMT11
uniprot id: A0A8B7H8J2
uniprot id: A0A8B7H8J9
uniprot id: A0A8C5W1N5
names: Function
names: Subunit
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.
messages: Interacts with TRMT112.

30608:LOC105877524
gene id: 30608:LOC105877524
uniprot id: A0A8B7H5A4
uniprot id: A0A8B7H5D4
uniprot id: A0A8B7H7L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

30608:HSPA4L
gene id: 30608:HSPA4L
uniprot id: A0A8B7I6F4
uniprot id: A0A8B7I6F8
uniprot id: A0A8B7I9P5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

30608:LOC105871782
gene id: 30608:LOC105871782
uniprot id: A0A8B7GDN6
uniprot id: A0A8B7GEE2
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

30608:TMPRSS2
gene id: 30608:TMPRSS2
uniprot id: A0A8B7FAZ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:FAM149B1
gene id: 30608:FAM149B1
uniprot id: A0A8B7WL62
names: Similarity
messages: Belongs to the FAM149 family.

30608:GLUD1
gene id: 30608:GLUD1
uniprot id: A0A8C5VE81
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

30608:ELF1
gene id: 30608:ELF1
uniprot id: A0A8B7GDC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:CACNG5
gene id: 30608:CACNG5
uniprot id: A0A8B7F5E8
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

30608:SNAPIN
gene id: 30608:SNAPIN
uniprot id: A0A8B7I8X3
uniprot id: A0A8C5XT21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAPIN family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling.
messages: synaptic vesicle membrane

30608:PPM1D
gene id: 30608:PPM1D
uniprot id: A0A8B7H4X2
uniprot id: A0A8C5Y6T9
names: Similarity
messages: Belongs to the PP2C family.

30608:GPX2
gene id: 30608:GPX2
uniprot id: A0A8B7H938
names: Similarity
messages: Belongs to the glutathione peroxidase family.

30608:MAP2K2
gene id: 30608:MAP2K2
uniprot id: A0A8B7GQ49
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:CCKBR
gene id: 30608:CCKBR
uniprot id: A0A8B7HV89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

30608:ATP5J2
gene id: 30608:ATP5J2
uniprot id: A0A8B7FY98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

30608:IDE
gene id: 30608:IDE
uniprot id: A0A8B7GG27
names: Similarity
messages: Belongs to the peptidase M16 family.

30608:LOC105883330
gene id: 30608:LOC105883330
uniprot id: A0A8B7HUS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:DLAT
gene id: 30608:DLAT
uniprot id: A0A8C5W097
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Mitochondrion matrix
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

30608:DRAM1
gene id: 30608:DRAM1
uniprot id: A0A8B7X7H0
uniprot id: A0A8B7X8I0
names: Subcellular Location Annotation
messages: Membrane

30608:USP29
gene id: 30608:USP29
uniprot id: A0A8B7F8A3
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

30608:DSC1
gene id: 30608:DSC1
uniprot id: A0A8B7EED4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

30608:FRK
gene id: 30608:FRK
uniprot id: A0A8B7FJC2
uniprot id: A0A8B7FKS0
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

30608:LOC105864410
gene id: 30608:LOC105864410
uniprot id: A0A8B7FIA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SEH1L
gene id: 30608:SEH1L
uniprot id: A0A8B7WRU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore.
messages: Lysosome membrane
messages: kinetochore

30608:RGS9BP
gene id: 30608:RGS9BP
uniprot id: A0A8B7H320
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

30608:OLFML2B
gene id: 30608:OLFML2B
uniprot id: A0A8B7GM02
uniprot id: A0A8B7GMB9
uniprot id: A0A8B7GMJ5
uniprot id: A0A8C5UHV1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105884161
gene id: 30608:LOC105884161
uniprot id: A0A8B7HYL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:N4BP3
gene id: 30608:N4BP3
uniprot id: A0A8C6EDX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N4BP3 family.
messages: Cytoplasmic vesicle
messages: Vesicle
messages: axon
messages: dendrite

30608:SQLE
gene id: 30608:SQLE
uniprot id: A0A8B7HSA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane

30608:LSM8
gene id: 30608:LSM8
uniprot id: A0A8C5YDK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

30608:HNF4A
gene id: 30608:HNF4A
uniprot id: A0A8B7HGN9
uniprot id: A0A8B7HGT4
uniprot id: A0A8B7HHF7
uniprot id: A0A8B7HJA9
uniprot id: A0A8C5UUG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

30608:DDC
gene id: 30608:DDC
uniprot id: A0A8B7EB14
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

30608:RGS1
gene id: 30608:RGS1
uniprot id: A0A8B7GWB5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cytosol

30608:LYRM2
gene id: 30608:LYRM2
uniprot id: A0A8B7FDP3
uniprot id: A0A8C5XIP3
names: Similarity
messages: Belongs to the complex I LYR family.

30608:SNTA1
gene id: 30608:SNTA1
uniprot id: A0A8C5Y1F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

30608:APTX
gene id: 30608:APTX
uniprot id: A0A8B7GQX4
uniprot id: A0A8B7GQY3
uniprot id: A0A8B7GR64
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus
messages: nucleoplasm

30608:BRIX1
gene id: 30608:BRIX1
uniprot id: A0A8B7XCV3
uniprot id: A0A8C5USE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRX1 family.
messages: Required for biogenesis of the 60S ribosomal subunit.
messages: nucleolus

30608:LDHAL6A
gene id: 30608:LDHAL6A
uniprot id: A0A8B7HIT7
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

30608:IL17RB
gene id: 30608:IL17RB
uniprot id: A0A8B7GUI0
uniprot id: A0A8B7GUM5
uniprot id: A0A8B7GUP8
uniprot id: A0A8B7GWC1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:ATL2
gene id: 30608:ATL2
uniprot id: A0A8B7I039
uniprot id: A0A8B7I050
uniprot id: A0A8B7I052
uniprot id: A0A8B7I283
uniprot id: A0A8B7X8X1
uniprot id: A0A8C5WAW4
uniprot id: A0A8C5Y0H9
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

30608:E2F1
gene id: 30608:E2F1
uniprot id: A0A8B7FP21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

30608:ETV3L
gene id: 30608:ETV3L
uniprot id: A0A8C5XE28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:LOC105863156
gene id: 30608:LOC105863156
uniprot id: A0A8B7FBA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105869307
gene id: 30608:LOC105869307
uniprot id: A0A8B7G2Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

30608:C28H4orf32
gene id: 30608:C28H4orf32
uniprot id: A0A8B7WXC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM241 family.
messages: Membrane

30608:ITGB7
gene id: 30608:ITGB7
uniprot id: A0A8B7G9D3
uniprot id: A0A8B7G9U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

30608:NAPB
gene id: 30608:NAPB
uniprot id: A0A8C5V9H4
uniprot id: A0A8C5VUM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

30608:NOXRED1
gene id: 30608:NOXRED1
uniprot id: A0A8B7ETH5
uniprot id: A0A8B7ETI0
uniprot id: A0A8B7ETI1
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

30608:YARS
gene id: 30608:YARS
uniprot id: A0A8C5UYC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Nucleus

30608:LOC105862128
gene id: 30608:LOC105862128
uniprot id: A0A8B7X1V6
uniprot id: A0A8B7X2J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:EXOC3L1
gene id: 30608:EXOC3L1
uniprot id: A0A8B7EU79
uniprot id: A0A8B7WS39
uniprot id: A0A8B7WS46
uniprot id: A0A8B7WS59
uniprot id: A0A8B7WS83
uniprot id: A0A8B7WTL3
names: Similarity
messages: Belongs to the SEC6 family.

30608:ADGRA3
gene id: 30608:ADGRA3
uniprot id: A0A8B7EEM7
uniprot id: A0A8B7EF80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

30608:STAT1
gene id: 30608:STAT1
uniprot id: A0A8B7H760
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

30608:GALNTL6
gene id: 30608:GALNTL6
uniprot id: A0A8B7WLF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

30608:GRIK4
gene id: 30608:GRIK4
uniprot id: A0A8B7GZ31
uniprot id: A0A8B7GZ36
uniprot id: A0A8B7GZ69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

30608:RSPO2
gene id: 30608:RSPO2
uniprot id: A0A8B7XC30
uniprot id: A0A8C5YCK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-spondin family.
messages: Secreted

30608:BCAT2
gene id: 30608:BCAT2
uniprot id: A0A8B7FLZ6
uniprot id: A0A8B7FM14
uniprot id: A0A8B7FM21
uniprot id: A0A8B7FM22
uniprot id: A0A8B7FN58
uniprot id: A0A8C5W621
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

30608:LOC105884518
gene id: 30608:LOC105884518
uniprot id: A0A8B7I2W1
uniprot id: A0A8B7X8W6
uniprot id: A0A8B7XAJ4
names: Similarity
messages: Belongs to the TTC39 family.

30608:PREP
gene id: 30608:PREP
uniprot id: A0A8C5VTT8
names: Similarity
messages: Belongs to the peptidase S9A family.

30608:PAX8
gene id: 30608:PAX8
uniprot id: A0A8B7EUR3
uniprot id: A0A8B7X288
uniprot id: A0A8B7X291
uniprot id: A0A8B7X2S7
uniprot id: A0A8B7X3K9
uniprot id: A0A8B7X400
uniprot id: A0A8C5XMB1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

30608:TIMM21
gene id: 30608:TIMM21
uniprot id: A0A8C5VJU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane
messages: Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.

30608:TEX10
gene id: 30608:TEX10
uniprot id: A0A8B7GMX0
names: Similarity
messages: Belongs to the IPI1/TEX10 family.

30608:RALY
gene id: 30608:RALY
uniprot id: A0A8B7FMV8
uniprot id: A0A8B7FNB6
uniprot id: A0A8B7FP71
uniprot id: A0A8C5Y6F9
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

30608:LOC109731349
gene id: 30608:LOC109731349
uniprot id: A0A8B7XDG0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:POLR2A
gene id: 30608:POLR2A
uniprot id: A0A8B7H5T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

30608:LOC105869873
gene id: 30608:LOC105869873
uniprot id: A0A8B7G5D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

30608:LOC105869299
gene id: 30608:LOC105869299
uniprot id: A0A8B7G2Y4
uniprot id: A0A8B7G4C6
uniprot id: A0A8B7WWR7
uniprot id: A0A8B7WX38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

30608:SLC10A4
gene id: 30608:SLC10A4
uniprot id: A0A8B7GMN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

30608:NAXD
gene id: 30608:NAXD
uniprot id: A0A8B7FG89
uniprot id: A0A8B7FGA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Mitochondrion

30608:GATA6
gene id: 30608:GATA6
uniprot id: A0A8B7F1K4
names: Subcellular Location Annotation
messages: Nucleus

30608:TNR
gene id: 30608:TNR
uniprot id: A0A8B7GCX9
uniprot id: A0A8B7GDW1
uniprot id: A0A8B7X1S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

30608:NRDC
gene id: 30608:NRDC
uniprot id: A0A8B7H5H9
names: Similarity
messages: Belongs to the peptidase M16 family.

30608:TAAR9
gene id: 30608:TAAR9
uniprot id: A0A8B7EEZ6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:LOC105864759
gene id: 30608:LOC105864759
uniprot id: A0A8B7FIM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:STAC2
gene id: 30608:STAC2
uniprot id: A0A8B7GF69
uniprot id: A0A8B7GF82
uniprot id: A0A8B7GFP5
names: Subcellular Location Annotation
messages: sarcolemma

30608:LOC105869190
gene id: 30608:LOC105869190
uniprot id: A0A8B7G2L5
uniprot id: A0A8B7G3F9
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

30608:G6PC
gene id: 30608:G6PC
uniprot id: A0A8C5YDW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

30608:COQ9
gene id: 30608:COQ9
uniprot id: A0A8B7FF00
uniprot id: A0A8B7WSY9
uniprot id: A0A8C5XJF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

30608:RCAN2
gene id: 30608:RCAN2
uniprot id: A0A8B7FS81
uniprot id: A0A8B7FT62
uniprot id: A0A8C5VZI4
names: Function
names: Similarity
messages: Belongs to the RCAN family.
messages: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.

30608:SOGA3
gene id: 30608:SOGA3
uniprot id: A0A8C6EFN5
names: Similarity
messages: Belongs to the SOGA family.

30608:UBE2G2
gene id: 30608:UBE2G2
uniprot id: A0A8B7HEN2
uniprot id: A0A8B7HEQ2
uniprot id: A0A8B7HF15
uniprot id: A0A8C6EK79
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:CADM4
gene id: 30608:CADM4
uniprot id: A0A8B7G3K1
uniprot id: A0A8B7WW98
names: Similarity
messages: Belongs to the nectin family.

30608:DNASE1L3
gene id: 30608:DNASE1L3
uniprot id: A0A8B7I268
uniprot id: A0A8B7I269
uniprot id: A0A8C5VRT8
names: Similarity
messages: Belongs to the DNase I family.

30608:POMC
gene id: 30608:POMC
uniprot id: A0A8B7I1R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Anorexigenic peptide. Increases the pigmentation of skin by increasing melanin production in melanocytes.
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Endogenous orexigenic opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

30608:GPRC5A
gene id: 30608:GPRC5A
uniprot id: A0A8C5V3L8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:LOC105880160
gene id: 30608:LOC105880160
uniprot id: A0A8B7HGZ4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

30608:TVP23A
gene id: 30608:TVP23A
uniprot id: A0A8B7HRF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

30608:TMEM177
gene id: 30608:TMEM177
uniprot id: A0A8B7F950
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

30608:DHRS3
gene id: 30608:DHRS3
uniprot id: A0A8B7HS60
uniprot id: A0A8B7WPL5
uniprot id: A0A8B7WPM0
uniprot id: A0A8B7WPR3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:DCLRE1A
gene id: 30608:DCLRE1A
uniprot id: A0A8B7GWB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

30608:DSTN
gene id: 30608:DSTN
uniprot id: A0A8C5VEP6
names: Function
names: Similarity
messages: Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner.
messages: Belongs to the actin-binding proteins ADF family.

30608:RFFL
gene id: 30608:RFFL
uniprot id: A0A8B7I2S6
uniprot id: A0A8B7I5W9
uniprot id: A0A8C5W3B9
names: Subcellular Location Annotation
messages: Cell membrane

30608:RYR3
gene id: 30608:RYR3
uniprot id: A0A8B7X2M3
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

30608:SVIL
gene id: 30608:SVIL
uniprot id: A0A8B7I1I9
uniprot id: A0A8B7I1J1
uniprot id: A0A8B7I1J5
uniprot id: A0A8B7I1J7
uniprot id: A0A8B7I1J8
uniprot id: A0A8B7I3L7
uniprot id: A0A8B7I3M2
uniprot id: A0A8B7I4D3
uniprot id: A0A8B7I4E0
uniprot id: A0A8B7I4E5
uniprot id: A0A8B7WWG6
uniprot id: A0A8B7WY71
names: Similarity
messages: Belongs to the villin/gelsolin family.

30608:LOC105883565
gene id: 30608:LOC105883565
uniprot id: A0A8B7HXX9
uniprot id: A0A8B7HY45
names: Subcellular Location Annotation
messages: nucleolus

30608:TMPRSS3
gene id: 30608:TMPRSS3
uniprot id: A0A8B7HCD8
uniprot id: A0A8B7HF10
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105861324
gene id: 30608:LOC105861324
uniprot id: A0A8B7F459
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MAP3K15
gene id: 30608:MAP3K15
uniprot id: A0A8B7HQI8
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

30608:BNIP3
gene id: 30608:BNIP3
uniprot id: A0A8B7WN91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

30608:LOC105878756
gene id: 30608:LOC105878756
uniprot id: A0A8B7HB27
names: Similarity
messages: Belongs to the TIP41 family.

30608:TMEM87A
gene id: 30608:TMEM87A
uniprot id: A0A8B7GGU1
uniprot id: A0A8B7GH86
uniprot id: A0A8B7GH90
uniprot id: A0A8B7GHI1
uniprot id: A0A8B7GHI6
names: Subcellular Location Annotation
messages: Membrane

30608:EFNA5
gene id: 30608:EFNA5
uniprot id: A0A8B7I4G7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:ARHGEF28
gene id: 30608:ARHGEF28
uniprot id: A0A8B7HMS6
uniprot id: A0A8B7HMU9
uniprot id: A0A8B7HMV0
uniprot id: A0A8B7HPB4
uniprot id: A0A8B7HPC1
uniprot id: A0A8B7HQ91
uniprot id: A0A8C5VD98
names: Subcellular Location Annotation
messages: Cytoplasm

30608:SPDEF
gene id: 30608:SPDEF
uniprot id: A0A8B7F2T1
uniprot id: A0A8C5XUQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:GNAZ
gene id: 30608:GNAZ
uniprot id: A0A8B7F9S9
names: Similarity
messages: Belongs to the G-alpha family. G(i/o/t/z) subfamily.

30608:LDB1
gene id: 30608:LDB1
uniprot id: A0A8B7GPI4
uniprot id: A0A8B7GPS9
uniprot id: A0A8B7GQ15
uniprot id: A0A8B7GQ29
uniprot id: A0A8B7GR15
uniprot id: A0A8B7GR27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDB family.
messages: Nucleus

30608:LOC105883420
gene id: 30608:LOC105883420
uniprot id: A0A8B7X423
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CRHBP
gene id: 30608:CRHBP
uniprot id: A0A8B7EJC6
uniprot id: A0A8B7XCZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

30608:MFSD1
gene id: 30608:MFSD1
uniprot id: A0A8B7EKG3
uniprot id: A0A8B7EKT0
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105883468
gene id: 30608:LOC105883468
uniprot id: A0A8B7HXK5
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105882543
gene id: 30608:LOC105882543
uniprot id: A0A8B7HTV3
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

30608:ASIC4
gene id: 30608:ASIC4
uniprot id: A0A8B7ELJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

30608:HSPA2
gene id: 30608:HSPA2
uniprot id: A0A8B7H8Z4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

30608:ANKS1A
gene id: 30608:ANKS1A
uniprot id: A0A8B7F2R4
uniprot id: A0A8B7F2R6
uniprot id: A0A8B7F2R7
uniprot id: A0A8B7F2S0
uniprot id: A0A8B7F2S2
uniprot id: A0A8B7F2S7
uniprot id: A0A8B7F3W2
uniprot id: A0A8B7F3W4
uniprot id: A0A8B7F466
uniprot id: A0A8C5XE97
names: Subcellular Location Annotation
messages: Cytoplasm

30608:WRNIP1
gene id: 30608:WRNIP1
uniprot id: A0A8C5XL38
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

30608:SLC9A5
gene id: 30608:SLC9A5
uniprot id: A0A8B7ES51
uniprot id: A0A8B7ETX3
uniprot id: A0A8B7EU69
uniprot id: A0A8B7WT07
uniprot id: A0A8B7WUG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Membrane

30608:MID1IP1
gene id: 30608:MID1IP1
uniprot id: A0A8C5XSI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

30608:DKK4
gene id: 30608:DKK4
uniprot id: A0A8B7WRV7
uniprot id: A0A8B7WTB9
uniprot id: A0A8C5YE62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

30608:ATP6V1A
gene id: 30608:ATP6V1A
uniprot id: A0A8B7HXQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: clathrin-coated vesicle membrane
messages: secretory vesicle

30608:LOC105875664
gene id: 30608:LOC105875664
uniprot id: A0A8B7WLK2
uniprot id: A0A8B7WLK7
uniprot id: A0A8B7WLL4
uniprot id: A0A8B7WLL9
uniprot id: A0A8B7WLM3
uniprot id: A0A8B7WLP0
uniprot id: A0A8B7WLP5
uniprot id: A0A8B7WLR6
uniprot id: A0A8B7WML5
uniprot id: A0A8B7WMM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferlin family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

30608:LOC105882200
gene id: 30608:LOC105882200
uniprot id: A0A8B7HS75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:POLR2E
gene id: 30608:POLR2E
uniprot id: A0A8B7F077
uniprot id: A0A8B7F080
uniprot id: A0A8B7F081
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
messages: Nucleus

30608:NLRP14
gene id: 30608:NLRP14
uniprot id: A0A8B7EWH9
uniprot id: A0A8B7EWI4
uniprot id: A0A8B7EYI5
names: Similarity
messages: Belongs to the NLRP family.

30608:ATP1B1
gene id: 30608:ATP1B1
uniprot id: A0A8B7HNP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Cell membrane
messages: Involved in cell adhesion and establishing epithelial cell polarity.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.
messages: sarcolemma

30608:UBE2D1
gene id: 30608:UBE2D1
uniprot id: A0A8B7G7J5
uniprot id: A0A8C5VFP7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:PFKL
gene id: 30608:PFKL
uniprot id: A0A8B7HCE8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ST6GALNAC2
gene id: 30608:ST6GALNAC2
uniprot id: A0A8B7HEN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

30608:GRM1
gene id: 30608:GRM1
uniprot id: A0A8B7X6Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

30608:VPS26B
gene id: 30608:VPS26B
uniprot id: A0A8C5XKB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS26 family.
messages: Endosome

30608:CEP290
gene id: 30608:CEP290
uniprot id: A0A8B7FVH3
uniprot id: A0A8B7FVH4
uniprot id: A0A8B7FVM9
uniprot id: A0A8B7FWF4
uniprot id: A0A8B7FWG2
uniprot id: A0A8B7FWG8
names: Subcellular Location Annotation
messages: cilium basal body

30608:DCC
gene id: 30608:DCC
uniprot id: A0A8B7F1S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. DCC family.
messages: Membrane

30608:METTL6
gene id: 30608:METTL6
uniprot id: A0A8B7GI66
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.

30608:C1QBP
gene id: 30608:C1QBP
uniprot id: A0A8B7HD31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAM33 family.
messages: Cell membrane

30608:LOC105864421
gene id: 30608:LOC105864421
uniprot id: A0A8B7FH95
names: Subcellular Location Annotation
messages: Membrane

30608:NMI
gene id: 30608:NMI
uniprot id: A0A8B7HEJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NMI family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

30608:PANX2
gene id: 30608:PANX2
uniprot id: A0A8B7I5S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

30608:LOC109731106
gene id: 30608:LOC109731106
uniprot id: A0A8B7X9X6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

30608:LOC105862235
gene id: 30608:LOC105862235
uniprot id: A0A8B7F7L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

30608:MYH7B
gene id: 30608:MYH7B
uniprot id: A0A8B7FN83
uniprot id: A0A8B7FPC3
uniprot id: A0A8B7WQ57
uniprot id: A0A8B7WQ62
uniprot id: A0A8B7WQ63
uniprot id: A0A8B7WQ65
uniprot id: A0A8B7WQ68
uniprot id: A0A8B7WQ71
uniprot id: A0A8B7WQA4
uniprot id: A0A8B7WQB0
uniprot id: A0A8B7WRL9
uniprot id: A0A8B7WRM7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

30608:CD99L2
gene id: 30608:CD99L2
uniprot id: A0A8B7FJM5
uniprot id: A0A8C5XYV2
uniprot id: A0A8C5Y0G7
names: Similarity
messages: Belongs to the CD99 family.

30608:DUSP27
gene id: 30608:DUSP27
uniprot id: A0A8B7EZ84
uniprot id: A0A8B7F1G2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

30608:NMNAT3
gene id: 30608:NMNAT3
uniprot id: A0A8B7G654
uniprot id: A0A8B7G6W4
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

30608:ATP6V1F
gene id: 30608:ATP6V1F
uniprot id: A0A8B7I4R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

30608:GABRA1
gene id: 30608:GABRA1
uniprot id: A0A8B7FIZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:C5H11orf54
gene id: 30608:C5H11orf54
uniprot id: A0A8B7EK73
uniprot id: A0A8B7ELF8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

30608:LOC105883335
gene id: 30608:LOC105883335
uniprot id: A0A8B7HWY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105863327
gene id: 30608:LOC105863327
uniprot id: A0A8B7H411
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

30608:MBOAT2
gene id: 30608:MBOAT2
uniprot id: A0A8B7HT31
uniprot id: A0A8B7HT38
uniprot id: A0A8B7HV55
names: Subcellular Location Annotation
messages: Membrane

30608:SLC25A10
gene id: 30608:SLC25A10
uniprot id: A0A8B7I2H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:DLL4
gene id: 30608:DLL4
uniprot id: A0A8B7GH01
uniprot id: A0A8C5XI83
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

30608:ACOX2
gene id: 30608:ACOX2
uniprot id: A0A8B7I2A5
uniprot id: A0A8B7WL50
uniprot id: A0A8C5Y398
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

30608:SLC30A10
gene id: 30608:SLC30A10
uniprot id: A0A8B7I7C0
uniprot id: A0A8B7I7I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

30608:SIGIRR
gene id: 30608:SIGIRR
uniprot id: A0A8C5Y9K4
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

30608:GBX1
gene id: 30608:GBX1
uniprot id: A0A8B7HWH4
names: Subcellular Location Annotation
messages: Nucleus

30608:SLITRK3
gene id: 30608:SLITRK3
uniprot id: A0A8B7HM51
names: Similarity
messages: Belongs to the SLITRK family.

30608:TOR1A
gene id: 30608:TOR1A
uniprot id: A0A8C5UVJ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum lumen
messages: Homohexamer. Interacts with TOR1B; the interaction may be specific of neural tissues. Interacts (ATP-bound) with TOR1AIP1 and TOR1AIP2; the interactions induce ATPase activity. Interacts with KLHL14; preferentially when ATP-free. Interacts with KLC1 (via TPR repeats); the interaction associates TOR1A with the kinesin oligomeric complex. Interacts with COPS4; the interaction associates TOR1A with the CSN complex. Interacts with SNAPIN; the interaction is direct and associates SNAPIN with the CSN complex. Interacts with STON2. Interacts (ATP-bound) with SYNE3 (via KASH domain); the interaction is required for SYNE3 nuclear envelope localization. Interacts with VIM; the interaction associates TOR1A with the cytoskeleton. Interacts with PLEC. Interacts (ATP-bound) with SLC6A3; regulates SLC6A3 transport to the plasma membrane.
messages: Membrane
messages: growth cone

30608:OAS1
gene id: 30608:OAS1
uniprot id: A0A8B7FS18
uniprot id: A0A8B7FT09
uniprot id: A0A8B7WTS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-5A synthase family.
messages: Cytoplasm

30608:PSMD8
gene id: 30608:PSMD8
uniprot id: A0A8C5Y7Q5
names: Similarity
messages: Belongs to the proteasome subunit S14 family.

30608:LOC105867906
gene id: 30608:LOC105867906
uniprot id: A0A8B7FXI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SIM2
gene id: 30608:SIM2
uniprot id: A0A8B7HLD4
uniprot id: A0A8B7WYK3
names: Subcellular Location Annotation
messages: Nucleus

30608:MMACHC
gene id: 30608:MMACHC
uniprot id: A0A8B7H4Z6
names: Similarity
messages: Belongs to the MMACHC family.

30608:AMH
gene id: 30608:AMH
uniprot id: A0A8B7F1U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Plays an important role in several reproductive functions. Induces Muellerian duct regression during male fetal sexual differentiation and plays a role in Leydig cell differentiation and function. In female acts as a negative regulator of the primordial to primary follicle transition and decreases FSH sensitivity of growing follicles. AMH signals by binding to a specific type-II receptor, AMHR2, that heterodimerizes with type-I receptors (ACVR1 and BMPR1A), and recruiting SMAD proteins that are translocated to the nucleus to regulate target gene expression.
messages: Secreted

30608:FBL
gene id: 30608:FBL
uniprot id: A0A8B7H1P8
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

30608:VASN
gene id: 30608:VASN
uniprot id: A0A8B7EVA9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:CDH3
gene id: 30608:CDH3
uniprot id: A0A8B7WTH7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

30608:TRPM2
gene id: 30608:TRPM2
uniprot id: A0A8B7WXZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM2 sub-subfamily.
messages: Cell membrane
messages: Membrane

30608:PCMTD2
gene id: 30608:PCMTD2
uniprot id: A0A8B7GY03
uniprot id: A0A8B7GY07
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

30608:LPCAT3
gene id: 30608:LPCAT3
uniprot id: A0A8B7G1J1
names: Subcellular Location Annotation
messages: Membrane

30608:CSF3R
gene id: 30608:CSF3R
uniprot id: A0A8B7GDB6
uniprot id: A0A8B7GDW2
uniprot id: A0A8B7GE97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

30608:GBGT1
gene id: 30608:GBGT1
uniprot id: A0A8B7EW83
uniprot id: A0A8B7EY56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

30608:LOC105882163
gene id: 30608:LOC105882163
uniprot id: A0A8B7HPN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TADA3
gene id: 30608:TADA3
uniprot id: A0A8B7G1X0
uniprot id: A0A8B7G2S9
uniprot id: A0A8B7G3B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

30608:ACLY
gene id: 30608:ACLY
uniprot id: A0A8B7GES0
uniprot id: A0A8B7GF83
uniprot id: A0A8B7GFM0
uniprot id: A0A8C5VNM4
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

30608:EXOSC9
gene id: 30608:EXOSC9
uniprot id: A0A8B7HPF1
uniprot id: A0A8C5UX05
names: Subcellular Location Annotation
messages: Cytoplasm

30608:LOC105857906
gene id: 30608:LOC105857906
uniprot id: A0A8B7EMJ1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

30608:PSMG1
gene id: 30608:PSMG1
uniprot id: A0A8B7HIQ9
uniprot id: A0A8B7WZ06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG1 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.
messages: Forms a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer interacts directly with the PSMA5 and PSMA7 proteasome alpha subunits.

30608:MIS12
gene id: 30608:MIS12
uniprot id: A0A8B7HD29
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mis12 family.
messages: Component of the MIS12 complex composed of MIS12, DSN1, NSL1 and PMF1. Also interacts with KNL1, CBX3, CBX5, NDC80 and ZWINT.
messages: kinetochore

30608:LOC105862112
gene id: 30608:LOC105862112
uniprot id: A0A8B7F700
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PRPF19
gene id: 30608:PRPF19
uniprot id: A0A8B7HAQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Lipid droplet
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

30608:ACTL9
gene id: 30608:ACTL9
uniprot id: A0A8B7I7U7
names: Similarity
messages: Belongs to the actin family.

30608:DMD
gene id: 30608:DMD
uniprot id: A0A8B7FT92
uniprot id: A0A8B7FT98
uniprot id: A0A8B7FTA1
uniprot id: A0A8B7FTA8
uniprot id: A0A8B7FTD9
uniprot id: A0A8B7FU09
uniprot id: A0A8B7FU16
uniprot id: A0A8B7FU96
names: Subcellular Location Annotation
messages: cytoskeleton

30608:MED28
gene id: 30608:MED28
uniprot id: A0A8C5V930
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 28 family.
messages: Nucleus

30608:HDHD3
gene id: 30608:HDHD3
uniprot id: A0A8B7GMM7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

30608:LOC105856759
gene id: 30608:LOC105856759
uniprot id: A0A8B7EHK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105868334
gene id: 30608:LOC105868334
uniprot id: A0A8B7FYB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

30608:ITM2A
gene id: 30608:ITM2A
uniprot id: A0A8C5XLG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

30608:FOXJ1
gene id: 30608:FOXJ1
uniprot id: A0A8B7HBY2
names: Subcellular Location Annotation
messages: Nucleus

30608:IYD
gene id: 30608:IYD
uniprot id: A0A8C5XJR2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasmic vesicle membrane

30608:STAT5B
gene id: 30608:STAT5B
uniprot id: A0A8B7EVZ2
uniprot id: A0A8C5W177
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

30608:TMBIM1
gene id: 30608:TMBIM1
uniprot id: A0A8B7ELK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

30608:CBX6
gene id: 30608:CBX6
uniprot id: A0A8B7EQN0
names: Subcellular Location Annotation
messages: Nucleus

30608:SLC16A6
gene id: 30608:SLC16A6
uniprot id: A0A8B7F598
uniprot id: A0A8B7F5A7
uniprot id: A0A8C5Y2E0
names: Subcellular Location Annotation
messages: Membrane

30608:SV2B
gene id: 30608:SV2B
uniprot id: A0A8C5VB35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

30608:RPL27
gene id: 30608:RPL27
uniprot id: A0A8C5V1X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

30608:AMER2
gene id: 30608:AMER2
uniprot id: A0A8B7ED43
uniprot id: A0A8B7EDP0
names: Similarity
messages: Belongs to the Amer family.

30608:MTFR1
gene id: 30608:MTFR1
uniprot id: A0A8B7EDX8
uniprot id: A0A8B7EEI4
uniprot id: A0A8B7EGI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

30608:NME5
gene id: 30608:NME5
uniprot id: A0A8B7F979
uniprot id: A0A8B7F9N8
names: Similarity
messages: Belongs to the NDK family.

30608:PGLYRP3
gene id: 30608:PGLYRP3
uniprot id: A0A8B7I742
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

30608:MGAT4C
gene id: 30608:MGAT4C
uniprot id: A0A8B7EZT3
uniprot id: A0A8C5VI54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 54 family.
messages: Golgi apparatus membrane

30608:KIF2B
gene id: 30608:KIF2B
uniprot id: A0A8B7G9Q3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:FPGS
gene id: 30608:FPGS
uniprot id: A0A8B7GVG1
uniprot id: A0A8B7GVG2
uniprot id: A0A8B7GVH4
uniprot id: A0A8B7GVH8
uniprot id: A0A8B7GX81
names: Cofactor
names: Function
names: Similarity
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.

30608:MGA
gene id: 30608:MGA
uniprot id: A0A8B7GGN3
uniprot id: A0A8B7GH33
uniprot id: A0A8B7GHE1
uniprot id: A0A8B7GHI5
uniprot id: A0A8B7X2R7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

30608:LSM7
gene id: 30608:LSM7
uniprot id: A0A8B7GP09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

30608:PLEC
gene id: 30608:PLEC
uniprot id: A0A8B7G0P3
uniprot id: A0A8B7G0P9
uniprot id: A0A8B7G0Q0
uniprot id: A0A8B7G0Q4
uniprot id: A0A8B7G0Q6
uniprot id: A0A8B7G0Q8
uniprot id: A0A8B7G0R0
uniprot id: A0A8B7G0R2
uniprot id: A0A8B7G0R3
uniprot id: A0A8B7G0R6
uniprot id: A0A8B7G0R7
uniprot id: A0A8B7G0R8
uniprot id: A0A8B7G0S1
uniprot id: A0A8B7G0S2
uniprot id: A0A8B7G0S3
uniprot id: A0A8B7G0S9
uniprot id: A0A8B7G0T1
uniprot id: A0A8B7G1K3
uniprot id: A0A8B7G1K8
uniprot id: A0A8B7G1L8
uniprot id: A0A8B7G1M4
uniprot id: A0A8B7G1M9
uniprot id: A0A8B7G204
uniprot id: A0A8B7G224
uniprot id: A0A8C5VEG5
uniprot id: A0A8C5VT96
uniprot id: A0A8C5XVE7
names: Subcellular Location Annotation
messages: cytoskeleton

30608:SPRR3
gene id: 30608:SPRR3
uniprot id: A0A8B7X095
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornifin (SPRR) family.
messages: Cytoplasm

30608:BRPF1
gene id: 30608:BRPF1
uniprot id: A0A8B7G1V2
uniprot id: A0A8B7G1V5
uniprot id: A0A8B7G1V6
uniprot id: A0A8B7G1V9
uniprot id: A0A8B7G2R2
uniprot id: A0A8B7G2R6
uniprot id: A0A8B7WWU0
uniprot id: A0A8B7WWU3
uniprot id: A0A8B7WXM3
uniprot id: A0A8B7WYK1
uniprot id: A0A8C5XEJ9
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105870380
gene id: 30608:LOC105870380
uniprot id: A0A8B7X7K4
names: Similarity
messages: Belongs to the intermediate filament family.

30608:LOC105879450
gene id: 30608:LOC105879450
uniprot id: A0A8B7XG93
names: Subcellular Location Annotation
messages: Membrane

30608:USE1
gene id: 30608:USE1
uniprot id: A0A8B7FPY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:SATB2
gene id: 30608:SATB2
uniprot id: A0A8B7EJW1
uniprot id: A0A8B7X9W8
uniprot id: A0A8C5XVA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

30608:KLC4
gene id: 30608:KLC4
uniprot id: A0A8B7GY98
uniprot id: A0A8B7H046
uniprot id: A0A8C5V7T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

30608:RPS5
gene id: 30608:RPS5
uniprot id: A0A8C5VJ30
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

30608:ENKD1
gene id: 30608:ENKD1
uniprot id: A0A8B7EU39
names: Subcellular Location Annotation
messages: cilium axoneme

30608:P3H2
gene id: 30608:P3H2
uniprot id: A0A8B7F0P6
names: Similarity
messages: Belongs to the leprecan family.

30608:SLC17A2
gene id: 30608:SLC17A2
uniprot id: A0A8B7EPB7
uniprot id: A0A8B7WKD2
uniprot id: A0A8B7WKF2
uniprot id: A0A8B7WKG5
uniprot id: A0A8C5VCQ4
names: Subcellular Location Annotation
messages: Membrane

30608:SPCS1
gene id: 30608:SPCS1
uniprot id: A0A8C5Y7I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:CDH6
gene id: 30608:CDH6
uniprot id: A0A8B7XCU5
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

30608:NAV1
gene id: 30608:NAV1
uniprot id: A0A8B7EYT1
names: Similarity
messages: Belongs to the Nav/unc-53 family.

30608:GPR18
gene id: 30608:GPR18
uniprot id: A0A8B7FR03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane

30608:LPAR6
gene id: 30608:LPAR6
uniprot id: A0A8B7EE31
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:LOC105866385
gene id: 30608:LOC105866385
uniprot id: A0A8B7FQS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:DOLPP1
gene id: 30608:DOLPP1
uniprot id: A0A8B7GVW8
uniprot id: A0A8B7GVX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

30608:LOC105857697
gene id: 30608:LOC105857697
uniprot id: A0A8B7ELN1
uniprot id: A0A8B7ELN2
uniprot id: A0A8B7ELX4
uniprot id: A0A8B7ELX7
uniprot id: A0A8B7EN13
uniprot id: A0A8B7ENX6
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

30608:NT5DC2
gene id: 30608:NT5DC2
uniprot id: A0A8B7GU80
uniprot id: A0A8B7GU85
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

30608:MTMR3
gene id: 30608:MTMR3
uniprot id: A0A8B7G9Y3
uniprot id: A0A8B7G9Y9
uniprot id: A0A8B7G9Z3
uniprot id: A0A8B7GAA4
uniprot id: A0A8B7GAK0
uniprot id: A0A8B7GB11
uniprot id: A0A8C5W3X5
uniprot id: A0A8C5YGH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

30608:VPS29
gene id: 30608:VPS29
uniprot id: A0A8B7HK11
uniprot id: A0A8B7HK12
uniprot id: A0A8B7HL73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
messages: Belongs to the VPS29 family.
messages: Endosome membrane

30608:FAT2
gene id: 30608:FAT2
uniprot id: A0A8C5Y4M6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:GRIA4
gene id: 30608:GRIA4
uniprot id: A0A8B7F8D2
uniprot id: A0A8B7F8E1
uniprot id: A0A8B7F8H2
uniprot id: A0A8B7F8R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

30608:PIM2
gene id: 30608:PIM2
uniprot id: A0A8B7EIM8
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:PLEKHO1
gene id: 30608:PLEKHO1
uniprot id: A0A8B7FLQ9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:MSI2
gene id: 30608:MSI2
uniprot id: A0A8B7FRS5
uniprot id: A0A8B7FT46
uniprot id: A0A8B7FV88
uniprot id: A0A8B7FX02
uniprot id: A0A8B7FZS7
uniprot id: A0A8B7G2A9
uniprot id: A0A8B7G412
uniprot id: A0A8B7G475
uniprot id: A0A8B7G4G5
uniprot id: A0A8B7G558
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

30608:KCNE5
gene id: 30608:KCNE5
uniprot id: A0A8B7FC60
names: Similarity
messages: Belongs to the potassium channel KCNE family.

30608:FAM136A
gene id: 30608:FAM136A
uniprot id: A0A8B7FBV5
uniprot id: A0A8B7FBV9
uniprot id: A0A8B7FCJ1
names: Similarity
messages: Belongs to the FAM136 family.

30608:TMEM254
gene id: 30608:TMEM254
uniprot id: A0A8B7G6S0
names: Subcellular Location Annotation
messages: Membrane

30608:FGFR1OP2
gene id: 30608:FGFR1OP2
uniprot id: A0A8B7EJX4
uniprot id: A0A8B7EK85
uniprot id: A0A8C5XMD9
names: Similarity
messages: Belongs to the SIKE family.

30608:ATL3
gene id: 30608:ATL3
uniprot id: A0A8B7H9E2
uniprot id: A0A8B7H9F5
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

30608:LOC105856762
gene id: 30608:LOC105856762
uniprot id: A0A8B7EHJ9
uniprot id: A0A8B7EIK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

30608:IGFBP5
gene id: 30608:IGFBP5
uniprot id: A0A8C5VAM4
names: Caution
names: Function
names: Subcellular Location Annotation
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:LOC105876024
gene id: 30608:LOC105876024
uniprot id: A0A8B7GZ86
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:MRFAP1
gene id: 30608:MRFAP1
uniprot id: A0A8B7F5X7
names: Similarity
messages: Belongs to the MORF4 family-associated protein family.

30608:SLC24A3
gene id: 30608:SLC24A3
uniprot id: A0A8B7WQ60
uniprot id: A0A8C5Y2M6
uniprot id: A0A8C6EHZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

30608:FADD
gene id: 30608:FADD
uniprot id: A0A8C5Y0E5
names: Function
messages: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

30608:LOC105855896
gene id: 30608:LOC105855896
uniprot id: A0A8B7WSP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

30608:CCDC85C
gene id: 30608:CCDC85C
uniprot id: A0A8B7X0I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

30608:NGFR
gene id: 30608:NGFR
uniprot id: A0A8B7I324
uniprot id: A0A8B7I624
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:CTBP1
gene id: 30608:CTBP1
uniprot id: A0A8B7HMG4
uniprot id: A0A8B7HMG5
uniprot id: A0A8B7HNX9
uniprot id: A0A8C5XS62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

30608:CHRNA3
gene id: 30608:CHRNA3
uniprot id: A0A8B7EJK4
uniprot id: A0A8B7EJW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:LOC105874213
gene id: 30608:LOC105874213
uniprot id: A0A8B7GQ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

30608:WDR12
gene id: 30608:WDR12
uniprot id: A0A8B7EIE9
uniprot id: A0A8C5Y294
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

30608:SLITRK4
gene id: 30608:SLITRK4
uniprot id: A0A8C5VPR1
names: Similarity
messages: Belongs to the SLITRK family.

30608:LOC105876736
gene id: 30608:LOC105876736
uniprot id: A0A8B7H1E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF152 family.
messages: Lysosome membrane
messages: Membrane

30608:GLB1L
gene id: 30608:GLB1L
uniprot id: A0A8B7ELG8
uniprot id: A0A8B7ELH6
uniprot id: A0A8B7ENS3
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

30608:PTS
gene id: 30608:PTS
uniprot id: A0A8B7FAJ2
uniprot id: A0A8C5XVH5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the PTPS family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.

30608:ITK
gene id: 30608:ITK
uniprot id: A0A8B7HKU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cytoplasm

30608:LOC105867134
gene id: 30608:LOC105867134
uniprot id: A0A8B7FU32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

30608:LOC105869713
gene id: 30608:LOC105869713
uniprot id: A0A8B7WY90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SCOC
gene id: 30608:SCOC
uniprot id: A0A8B7HNJ0
uniprot id: A0A8C6EJJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCOC family.
messages: Positive regulator of amino acid starvation-induced autophagy.
messages: trans-Golgi network

30608:FAM155A
gene id: 30608:FAM155A
uniprot id: A0A8B7FFY8
uniprot id: A0A8B7FG72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NALF family.
messages: Membrane

30608:LOC105864586
gene id: 30608:LOC105864586
uniprot id: A0A8B7FHQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:IL1A
gene id: 30608:IL1A
uniprot id: A0A8B7ESY9
uniprot id: A0A8B7ESZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-1 family.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus
messages: Secreted

30608:SMC1A
gene id: 30608:SMC1A
uniprot id: A0A8B7F2G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

30608:SDC4
gene id: 30608:SDC4
uniprot id: A0A8B7HFZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

30608:KCNK18
gene id: 30608:KCNK18
uniprot id: A0A8C5V3R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

30608:C16H17orf105
gene id: 30608:C16H17orf105
uniprot id: A0A8B7HXQ4
uniprot id: A0A8B7HXU2
names: Similarity
messages: Belongs to the CFAP97 family.

30608:WARS2
gene id: 30608:WARS2
uniprot id: A0A8B7G550
uniprot id: A0A8B7G5U0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

30608:LOC105862155
gene id: 30608:LOC105862155
uniprot id: A0A8B7F777
uniprot id: A0A8B7F7A4
uniprot id: A0A8B7F7E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
messages: Belongs to the cytochrome P450 family.
messages: Interacts with FDX1/adrenodoxin.
messages: Mitochondrion inner membrane

30608:CASC3
gene id: 30608:CASC3
uniprot id: A0A8B7GF28
uniprot id: A0A8B7GFI8
uniprot id: A0A8B7GFV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASC3 family.
messages: Nucleus speckle
messages: dendrite
messages: perinuclear region

30608:STX1A
gene id: 30608:STX1A
uniprot id: A0A8B7ERE6
uniprot id: A0A8B7WNV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

30608:B3GNT4
gene id: 30608:B3GNT4
uniprot id: A0A8B7WTG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:RFX3
gene id: 30608:RFX3
uniprot id: A0A8B7EF87
uniprot id: A0A8B7EFA6
uniprot id: A0A8B7EFB5
uniprot id: A0A8B7EFI9
uniprot id: A0A8B7EHB0
uniprot id: A0A8B7EHH4
names: Subcellular Location Annotation
messages: Nucleus

30608:IDO1
gene id: 30608:IDO1
uniprot id: A0A8C5XAR1
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

30608:OXSM
gene id: 30608:OXSM
uniprot id: A0A8B7HUI3
uniprot id: A0A8B7HUK8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

30608:WAS
gene id: 30608:WAS
uniprot id: A0A8B7EG51
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105885163
gene id: 30608:LOC105885163
uniprot id: A0A8B7I5F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC109729195
gene id: 30608:LOC109729195
uniprot id: A0A8B7G6D9
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

30608:PON2
gene id: 30608:PON2
uniprot id: A0A8C5VHE6
names: Cofactor
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.

30608:KIF18A
gene id: 30608:KIF18A
uniprot id: A0A8B7F5P1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:NHP2
gene id: 30608:NHP2
uniprot id: A0A8C5Y8Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

30608:ATP10A
gene id: 30608:ATP10A
uniprot id: A0A8B7G1U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

30608:LOC105858219
gene id: 30608:LOC105858219
uniprot id: A0A8B7ER30
names: Similarity
messages: Belongs to the aldo/keto reductase family.

30608:NEK6
gene id: 30608:NEK6
uniprot id: A0A8C6EE99
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:CCT4
gene id: 30608:CCT4
uniprot id: A0A8B7X2N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

30608:DIAPH1
gene id: 30608:DIAPH1
uniprot id: A0A8B7F8X9
uniprot id: A0A8B7F8Y0
uniprot id: A0A8B7F928
names: Similarity
messages: Belongs to the formin homology family. Diaphanous subfamily.

30608:GPX4
gene id: 30608:GPX4
uniprot id: A0A8B7F094
uniprot id: A0A8B7F097
names: Similarity
messages: Belongs to the glutathione peroxidase family.

30608:MAP3K5
gene id: 30608:MAP3K5
uniprot id: A0A8B7EJM9
uniprot id: A0A8C6EI57
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

30608:ANAPC15
gene id: 30608:ANAPC15
uniprot id: A0A8B7EYC1
uniprot id: A0A8B7F0H2
names: Similarity
messages: Belongs to the APC15 family.

30608:ERGIC2
gene id: 30608:ERGIC2
uniprot id: A0A8B7F6L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

30608:PPP1R14D
gene id: 30608:PPP1R14D
uniprot id: A0A8B7GGZ6
uniprot id: A0A8B7GHE7
uniprot id: A0A8B7X1G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Cytoplasm
messages: Inhibitor of PPP1CA.
messages: Membrane

30608:TUBGCP4
gene id: 30608:TUBGCP4
uniprot id: A0A8B7GGZ8
uniprot id: A0A8B7GH03
uniprot id: A0A8B7GH05
uniprot id: A0A8B7GHE8
uniprot id: A0A8B7GHP9
uniprot id: A0A8B7GHV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

30608:TOMM7
gene id: 30608:TOMM7
uniprot id: A0A8C5XIT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom7 family.
messages: Membrane
messages: Mitochondrion outer membrane

30608:KDELC1
gene id: 30608:KDELC1
uniprot id: A0A8B7FGA8
names: Similarity
messages: Belongs to the KDELC family.

30608:DPYSL2
gene id: 30608:DPYSL2
uniprot id: A0A8B7H3G7
uniprot id: A0A8B7H5N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Homotetramer, and heterotetramer with CRMP1, DPYSL3, DPYSL4 or DPYSL5. Interacts through its C-terminus with the C-terminus of CYFIP1/SRA1. Interacts with HTR4. Interacts with CLN6. Interacts with MICALL1.
messages: Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.

30608:LOC105861497
gene id: 30608:LOC105861497
uniprot id: A0A8B7F3D6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:EPS8
gene id: 30608:EPS8
uniprot id: A0A8B7H4I6
names: Similarity
messages: Belongs to the EPS8 family.

30608:BCAR1
gene id: 30608:BCAR1
uniprot id: A0A8B7GWN4
uniprot id: A0A8B7GWP5
uniprot id: A0A8B7GWQ1
uniprot id: A0A8B7GWQ5
uniprot id: A0A8C5V0G0
uniprot id: A0A8C5VYK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

30608:SCNN1A
gene id: 30608:SCNN1A
uniprot id: A0A8B7G3G1
uniprot id: A0A8B7X6W4
uniprot id: A0A8B7X880
names: Subcellular Location Annotation
messages: Membrane

30608:KCNH1
gene id: 30608:KCNH1
uniprot id: A0A8B7HJJ2
uniprot id: A0A8B7HL41
uniprot id: A0A8B7WX55
names: Subcellular Location Annotation
messages: Membrane

30608:CHM
gene id: 30608:CHM
uniprot id: A0A8B7HQB1
uniprot id: A0A8C5VFT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

30608:LOC105856237
gene id: 30608:LOC105856237
uniprot id: A0A8B7EG39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

30608:CXCR6
gene id: 30608:CXCR6
uniprot id: A0A8C6ELA1
names: Function
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.

30608:ILKAP
gene id: 30608:ILKAP
uniprot id: A0A8B7X8Y1
names: Similarity
messages: Belongs to the PP2C family.

30608:CNEP1R1
gene id: 30608:CNEP1R1
uniprot id: A0A8B7I1B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNEP1R1 family.
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane

30608:WASL
gene id: 30608:WASL
uniprot id: A0A8C5VE95
names: Subcellular Location Annotation
messages: Nucleus

30608:RABAC1
gene id: 30608:RABAC1
uniprot id: A0A8C5W3S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

30608:SKIL
gene id: 30608:SKIL
uniprot id: A0A8B7HCX2
uniprot id: A0A8C5YH02
uniprot id: A0A8C5YIY7
names: Similarity
messages: Belongs to the SKI family.

30608:UCP3
gene id: 30608:UCP3
uniprot id: A0A8B7EY20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:EEF1A2
gene id: 30608:EEF1A2
uniprot id: A0A8B7GXR2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

30608:UBE2N
gene id: 30608:UBE2N
uniprot id: A0A8B7HS39
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:MYH11
gene id: 30608:MYH11
uniprot id: A0A8B7I4D1
uniprot id: A0A8B7I7G0
uniprot id: A0A8B7WNS3
uniprot id: A0A8B7WNT2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

30608:TUBB1
gene id: 30608:TUBB1
uniprot id: A0A8C5XK11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

30608:RIOX1
gene id: 30608:RIOX1
uniprot id: A0A8B7X2F3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family. NO66 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
messages: nucleolus

30608:CANX
gene id: 30608:CANX
uniprot id: A0A8B7I3N4
uniprot id: A0A8B7I5P1
uniprot id: A0A8B7I6R0
names: Similarity
messages: Belongs to the calreticulin family.

30608:SGMS1
gene id: 30608:SGMS1
uniprot id: A0A8B7G7U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

30608:FAM168B
gene id: 30608:FAM168B
uniprot id: A0A8B7FFR1
names: Similarity
messages: Belongs to the FAM168 family.

30608:GATM
gene id: 30608:GATM
uniprot id: A0A8B7GI55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the amidinotransferase family.
messages: Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine.
messages: Homodimer.
messages: Mitochondrion inner membrane

30608:CPA1
gene id: 30608:CPA1
uniprot id: A0A8B7I209
names: Similarity
messages: Belongs to the peptidase M14 family.

30608:MAP3K7
gene id: 30608:MAP3K7
uniprot id: A0A8B7FDT2
uniprot id: A0A8B7FDZ8
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by pro-inflammatory cytokines and in response to physical and chemical stresses, including osmotic stress, oxidative stress, arsenic and ultraviolet light irradiation. Activated by 'Lys-63'-linked polyubiquitination and by autophosphorylation.
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cytoplasm

30608:MPZ
gene id: 30608:MPZ
uniprot id: A0A8B7GLY3
uniprot id: A0A8B7GMH4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the myelin P0 protein family.
messages: Cell membrane
messages: Homodimer and homotetramer.

30608:FAT3
gene id: 30608:FAT3
uniprot id: A0A8B7X3Y2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PVALB
gene id: 30608:PVALB
uniprot id: A0A8B7HWR1
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

30608:LOC105868622
gene id: 30608:LOC105868622
uniprot id: A0A8C5UUH0
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

30608:LOC105863676
gene id: 30608:LOC105863676
uniprot id: A0A8B7FE58
names: Subcellular Location Annotation
messages: Membrane

30608:SCAND1
gene id: 30608:SCAND1
uniprot id: A0A8B7FP87
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105857881
gene id: 30608:LOC105857881
uniprot id: A0A8B7ENZ0
names: Subcellular Location Annotation
messages: Membrane

30608:TMPRSS11A
gene id: 30608:TMPRSS11A
uniprot id: A0A8B7G4A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

30608:LYPLA1
gene id: 30608:LYPLA1
uniprot id: A0A8B7I245
uniprot id: A0A8B7I457
uniprot id: A0A8B7I515
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

30608:TFAP2E
gene id: 30608:TFAP2E
uniprot id: A0A8C5Y9F9
names: Similarity
messages: Belongs to the AP-2 family.

30608:LOC105860315
gene id: 30608:LOC105860315
uniprot id: A0A8B7EY75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105882984
gene id: 30608:LOC105882984
uniprot id: A0A8B7WTV9
names: Function
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.
messages: Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction.

30608:CFI
gene id: 30608:CFI
uniprot id: A0A8B7GGR3
uniprot id: A0A8C5YBH2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:CAP2
gene id: 30608:CAP2
uniprot id: A0A8B7FKF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane

30608:LOC105871379
gene id: 30608:LOC105871379
uniprot id: A0A8B7GD17
names: Subcellular Location Annotation
messages: Membrane

30608:RNFT2
gene id: 30608:RNFT2
uniprot id: A0A8B7FSL4
uniprot id: A0A8B7FSN2
uniprot id: A0A8B7FTL7
names: Subcellular Location Annotation
messages: Membrane

30608:POLG2
gene id: 30608:POLG2
uniprot id: A0A8B7F511
uniprot id: A0A8B7F528
names: Subcellular Location Annotation
messages: Mitochondrion

30608:MYOD1
gene id: 30608:MYOD1
uniprot id: A0A8C5UY06
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: Nucleus

30608:GRAP
gene id: 30608:GRAP
uniprot id: A0A8B7F6L3
names: Similarity
messages: Belongs to the GRB2/sem-5/DRK family.

30608:FN3K
gene id: 30608:FN3K
uniprot id: A0A8B7H855
names: Similarity
messages: Belongs to the fructosamine kinase family.

30608:TPD52L2
gene id: 30608:TPD52L2
uniprot id: A0A8B7GXV8
uniprot id: A0A8B7GXW3
uniprot id: A0A8B7GXW6
uniprot id: A0A8B7GXX9
uniprot id: A0A8B7GY10
uniprot id: A0A8C5Y3M7
uniprot id: A0A8C5Y8V4
names: Similarity
messages: Belongs to the TPD52 family.

30608:USP27X
gene id: 30608:USP27X
uniprot id: A0A8B7WZG5
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

30608:HSPA14
gene id: 30608:HSPA14
uniprot id: A0A8B7EIG6
uniprot id: A0A8C5VV39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Component of ribosome-associated complex (RAC), a heterodimer composed of Hsp70/DnaK-type chaperone HSPA14 and Hsp40/DnaJ-type chaperone DNAJC2.
messages: Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity.
messages: cytosol

30608:VEGFA
gene id: 30608:VEGFA
uniprot id: A0A8C5XN05
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

30608:INSIG2
gene id: 30608:INSIG2
uniprot id: A0A8B7H433
uniprot id: A0A8B7XAP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

30608:C10H9orf78
gene id: 30608:C10H9orf78
uniprot id: A0A8C5VKE2
names: Similarity
messages: Belongs to the TLS1 family.

30608:ADAMTS14
gene id: 30608:ADAMTS14
uniprot id: A0A8B7G6X7
uniprot id: A0A8B7G7L3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:NIP7
gene id: 30608:NIP7
uniprot id: A0A8B7ERZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

30608:GALT
gene id: 30608:GALT
uniprot id: A0A8C5VV79
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.

30608:CCNJL
gene id: 30608:CCNJL
uniprot id: A0A8C5XYU4
names: Similarity
messages: Belongs to the cyclin family.

30608:TWF1
gene id: 30608:TWF1
uniprot id: A0A8B7F5S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

30608:LOC105878852
gene id: 30608:LOC105878852
uniprot id: A0A8B7HBD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TRIP10
gene id: 30608:TRIP10
uniprot id: A0A8B7G4Q8
uniprot id: A0A8B7G4R3
uniprot id: A0A8B7G4U4
uniprot id: A0A8B7G5J1
uniprot id: A0A8B7G637
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNBP1 family.
messages: Cell membrane
messages: Lysosome
messages: Membrane
messages: cell cortex

30608:AU129 gp02
gene id: 30608:AU129_gp02
uniprot id: A0A0U2S4M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion membrane

30608:LOC105876681
gene id: 30608:LOC105876681
uniprot id: A0A8B7X956
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105860197
gene id: 30608:LOC105860197
uniprot id: A0A8B7EXS9
uniprot id: A0A8B7EXT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

30608:PRKAA1
gene id: 30608:PRKAA1
uniprot id: A0A8B7H987
uniprot id: A0A8C5W9T9
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

30608:XPO6
gene id: 30608:XPO6
uniprot id: A0A8B7FYC3
uniprot id: A0A8B7FZ70
uniprot id: A0A8B7FZD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

30608:CDX2
gene id: 30608:CDX2
uniprot id: A0A8B7ERN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

30608:DERL2
gene id: 30608:DERL2
uniprot id: A0A8B7HD19
uniprot id: A0A8B7HD80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:RIPK2
gene id: 30608:RIPK2
uniprot id: A0A8C5UUT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Found in a signaling complex consisting of at least ARHGEF2, NOD2 and RIPK2.
messages: Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.

30608:AGAP3
gene id: 30608:AGAP3
uniprot id: A0A8C5W0T5
names: Similarity
messages: Belongs to the centaurin gamma-like family.

30608:IRX4
gene id: 30608:IRX4
uniprot id: A0A8C5W7A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

30608:LFNG
gene id: 30608:LFNG
uniprot id: A0A8B7FZ17
uniprot id: A0A8B7FZ46
uniprot id: A0A8B7G001
uniprot id: A0A8B7G088
uniprot id: A0A8B7WP09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:MCOLN3
gene id: 30608:MCOLN3
uniprot id: A0A8B7F5Q4
uniprot id: A0A8B7F5R2
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

30608:LOC105873261
gene id: 30608:LOC105873261
uniprot id: A0A8B7GKJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:BATF
gene id: 30608:BATF
uniprot id: A0A8B7ERN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

30608:LOC105859575
gene id: 30608:LOC105859575
uniprot id: A0A8B7EUI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TMC6
gene id: 30608:TMC6
uniprot id: A0A8B7FRS4
uniprot id: A0A8B7FRT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

30608:RASSF5
gene id: 30608:RASSF5
uniprot id: A0A8B7G2G1
names: Subcellular Location Annotation
messages: cytoskeleton

30608:SLC4A7
gene id: 30608:SLC4A7
uniprot id: A0A8B7HUQ4
uniprot id: A0A8B7HUR0
uniprot id: A0A8B7HUR9
uniprot id: A0A8B7HUS0
uniprot id: A0A8B7HUS2
uniprot id: A0A8B7HUT2
uniprot id: A0A8B7HUU1
uniprot id: A0A8B7HUU3
uniprot id: A0A8B7HUW5
uniprot id: A0A8B7HUW8
uniprot id: A0A8B7HWX8
uniprot id: A0A8B7HX21
uniprot id: A0A8B7WLZ0
uniprot id: A0A8C5YIC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

30608:MID1
gene id: 30608:MID1
uniprot id: A0A8B7HR09
uniprot id: A0A8B7HTC8
names: Function
names: Subcellular Location Annotation
messages: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
messages: cytoskeleton

30608:NKAP
gene id: 30608:NKAP
uniprot id: A0A8C5V0G9
names: Similarity
messages: Belongs to the NKAP family.

30608:SOX3
gene id: 30608:SOX3
uniprot id: A0A8B7FAZ5
names: Subcellular Location Annotation
messages: Nucleus

30608:AQP7
gene id: 30608:AQP7
uniprot id: A0A8B7GQW5
uniprot id: A0A8B7GR54
uniprot id: A0A8B7GR94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

30608:PIK3IP1
gene id: 30608:PIK3IP1
uniprot id: A0A8C5YDE7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105875117
gene id: 30608:LOC105875117
uniprot id: A0A8B7GUL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:GOLT1A
gene id: 30608:GOLT1A
uniprot id: A0A8B7FZ16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

30608:CSNK1A1L
gene id: 30608:CSNK1A1L
uniprot id: A0A8B7F734
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:GAB3
gene id: 30608:GAB3
uniprot id: A0A8B7ERK6
uniprot id: A0A8B7ERL0
uniprot id: A0A8B7ETC4
uniprot id: A0A8B7ETM4
uniprot id: A0A8C5VIB1
names: Similarity
messages: Belongs to the GAB family.

30608:GABRB1
gene id: 30608:GABRB1
uniprot id: A0A8B7WYF2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:UBA1
gene id: 30608:UBA1
uniprot id: A0A8B7FAM2
uniprot id: A0A8B7FB87
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

30608:LOC105861326
gene id: 30608:LOC105861326
uniprot id: A0A8B7F2Q1
names: Subcellular Location Annotation
messages: Membrane

30608:DTD2
gene id: 30608:DTD2
uniprot id: A0A8C5XP05
names: Similarity
messages: Belongs to the DTD family.

30608:SNX31
gene id: 30608:SNX31
uniprot id: A0A8B7X9U1
uniprot id: A0A8B7X9U5
uniprot id: A0A8B7XAJ2
uniprot id: A0A8B7XBI9
uniprot id: A0A8B7XBY1
uniprot id: A0A8B7XBY6
uniprot id: A0A8C5UWU0
names: Similarity
messages: Belongs to the sorting nexin family.

30608:CNDP2
gene id: 30608:CNDP2
uniprot id: A0A8C5VAM0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

30608:LOC105875436
gene id: 30608:LOC105875436
uniprot id: A0A8B7GWP4
uniprot id: A0A8C5VP65
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:GDI2
gene id: 30608:GDI2
uniprot id: A0A8B7EQH6
uniprot id: A0A8B7WWF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

30608:HSF4
gene id: 30608:HSF4
uniprot id: A0A8B7ESC1
uniprot id: A0A8B7ESC6
uniprot id: A0A8B7ESC8
uniprot id: A0A8B7ESD3
uniprot id: A0A8B7EU55
uniprot id: A0A8B7EUF0
uniprot id: A0A8C5UTU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

30608:SIM1
gene id: 30608:SIM1
uniprot id: A0A8B7X6D8
uniprot id: A0A8C5UZD1
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105881545
gene id: 30608:LOC105881545
uniprot id: A0A8B7X7B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
messages: Nucleus

30608:MSRB3
gene id: 30608:MSRB3
uniprot id: A0A8B7HK66
uniprot id: A0A8B7X5U9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

30608:FAM118B
gene id: 30608:FAM118B
uniprot id: A0A8B7GW70
uniprot id: A0A8B7X5I1
uniprot id: A0A8C5XLL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM118 family.
messages: Cajal body
messages: May play a role in Cajal bodies formation.

30608:LOC105869275
gene id: 30608:LOC105869275
uniprot id: A0A8B7WWN7
names: Subcellular Location Annotation
messages: Membrane

30608:TM2D3
gene id: 30608:TM2D3
uniprot id: A0A8C5VRS8
uniprot id: A0A8C5XYN3
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105866508
gene id: 30608:LOC105866508
uniprot id: A0A8B7XE65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

30608:STMN3
gene id: 30608:STMN3
uniprot id: A0A8B7GXS6
names: Function
names: Similarity
messages: Belongs to the stathmin family.
messages: Exhibits microtubule-destabilizing activity, which is antagonized by STAT3.

30608:PARD6B
gene id: 30608:PARD6B
uniprot id: A0A8B7GGK5
uniprot id: A0A8C5VEL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cell membrane
messages: Cytoplasm
messages: tight junction

30608:PNPLA7
gene id: 30608:PNPLA7
uniprot id: A0A8B7HQ08
uniprot id: A0A8B7HRS4
uniprot id: A0A8B7HSE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:STARD6
gene id: 30608:STARD6
uniprot id: A0A8B7EZP7
uniprot id: A0A8C5UZJ7
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

30608:LOC105879762
gene id: 30608:LOC105879762
uniprot id: A0A8B7HHV1
names: Similarity
messages: Belongs to the cystatin family.

30608:VPS28
gene id: 30608:VPS28
uniprot id: A0A8B7G133
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.
messages: Endosome membrane
messages: Membrane

30608:ATP9A
gene id: 30608:ATP9A
uniprot id: A0A8B7WQT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

30608:GUF1
gene id: 30608:GUF1
uniprot id: A0A8B7WWP2
uniprot id: A0A8C5Y4R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

30608:MED23
gene id: 30608:MED23
uniprot id: A0A8B7ECZ7
uniprot id: A0A8B7ED65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 23 family.
messages: Nucleus

30608:BMPR1B
gene id: 30608:BMPR1B
uniprot id: A0A8B7WYB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

30608:ELP3
gene id: 30608:ELP3
uniprot id: A0A8B7H3K8
uniprot id: A0A8B7WRZ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

30608:PSEN2
gene id: 30608:PSEN2
uniprot id: A0A8B7FEQ5
uniprot id: A0A8B7FES0
uniprot id: A0A8B7FES3
uniprot id: A0A8B7FES5
uniprot id: A0A8B7FES9
uniprot id: A0A8B7FEY9
uniprot id: A0A8B7FFR4
uniprot id: A0A8B7FFR9
uniprot id: A0A8C5V4P5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

30608:MCOLN2
gene id: 30608:MCOLN2
uniprot id: A0A8B7F5N5
uniprot id: A0A8B7F5N9
uniprot id: A0A8B7F5P0
uniprot id: A0A8B7F5P8
uniprot id: A0A8B7F5R1
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

30608:ADGRG3
gene id: 30608:ADGRG3
uniprot id: A0A8B7EVX2
names: Subcellular Location Annotation
messages: Membrane

30608:RBPMS2
gene id: 30608:RBPMS2
uniprot id: A0A8B7X270
uniprot id: A0A8C5Y4X3
names: Subcellular Location Annotation
messages: Cytoplasm

30608:FOXB2
gene id: 30608:FOXB2
uniprot id: A0A8C5XN97
names: Subcellular Location Annotation
messages: Nucleus

30608:NPEPL1
gene id: 30608:NPEPL1
uniprot id: A0A8B7GT96
names: Similarity
messages: Belongs to the peptidase M17 family.

30608:TXNDC8
gene id: 30608:TXNDC8
uniprot id: A0A8B7XDC9
names: Similarity
messages: Belongs to the thioredoxin family.

30608:LOC105867580
gene id: 30608:LOC105867580
uniprot id: A0A8B7FVJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative pheromone receptor.

30608:CLCN1
gene id: 30608:CLCN1
uniprot id: A0A8B7GKN9
uniprot id: A0A8B7GKP0
uniprot id: A0A8B7GL08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

30608:MALL
gene id: 30608:MALL
uniprot id: A0A8B7ET05
names: Subcellular Location Annotation
messages: Membrane

30608:RAD9A
gene id: 30608:RAD9A
uniprot id: A0A8C5W617
names: Similarity
messages: Belongs to the rad9 family.

30608:B3GALT6
gene id: 30608:B3GALT6
uniprot id: A0A8B7H5Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:LOC105855893
gene id: 30608:LOC105855893
uniprot id: A0A8B7EGF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTU2/NCS2 family.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

30608:CNTFR
gene id: 30608:CNTFR
uniprot id: A0A8B7GR13
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 3 subfamily.

30608:CPEB2
gene id: 30608:CPEB2
uniprot id: A0A8B7EEV6
uniprot id: A0A8B7EFF7
uniprot id: A0A8B7EFL0
uniprot id: A0A8B7EFL5
uniprot id: A0A8B7EHE5
uniprot id: A0A8B7EHF0
uniprot id: A0A8B7X2F0
uniprot id: A0A8C5VWM0
uniprot id: A0A8C5XGL0
names: Similarity
messages: Belongs to the RRM CPEB family.

30608:SLC16A5
gene id: 30608:SLC16A5
uniprot id: A0A8B7HBN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

30608:ARHGDIG
gene id: 30608:ARHGDIG
uniprot id: A0A8C5XDA5
names: Similarity
messages: Belongs to the Rho GDI family.

30608:LOC105872742
gene id: 30608:LOC105872742
uniprot id: A0A8C6EM39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PBX2
gene id: 30608:PBX2
uniprot id: A0A8B7EQT3
uniprot id: A0A8B7X5W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

30608:AU129 gp11
gene id: 30608:AU129_gp11
uniprot id: A0A0U2S4M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

30608:DGAT2
gene id: 30608:DGAT2
uniprot id: A0A8C5XXD2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ERH
gene id: 30608:ERH
uniprot id: A0A8C5XKD2
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

30608:DEFB134
gene id: 30608:DEFB134
uniprot id: A0A8B7WT18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

30608:LOC105882786
gene id: 30608:LOC105882786
uniprot id: A0A8B7WPK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA2 family.
messages: spindle

30608:SLC37A3
gene id: 30608:SLC37A3
uniprot id: A0A8B7GKG2
uniprot id: A0A8C5VA48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

30608:CNGA1
gene id: 30608:CNGA1
uniprot id: A0A8B7WXT4
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA1 subfamily.
messages: Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway. When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential.

30608:LOC105873222
gene id: 30608:LOC105873222
uniprot id: A0A8B7GKE4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

30608:KCNK4
gene id: 30608:KCNK4
uniprot id: A0A8B7H9M2
uniprot id: A0A8B7H9M4
uniprot id: A0A8B7H9M7
uniprot id: A0A8B7H9N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

30608:RAB39B
gene id: 30608:RAB39B
uniprot id: A0A8C5Y4R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

30608:SLC25A32
gene id: 30608:SLC25A32
uniprot id: A0A8B7HPM5
uniprot id: A0A8B7HRC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:KCNH5
gene id: 30608:KCNH5
uniprot id: A0A8B7H8Y1
uniprot id: A0A8B7X218
names: Subcellular Location Annotation
messages: Membrane

30608:EPGN
gene id: 30608:EPGN
uniprot id: A0A8B7F0Y5
uniprot id: A0A8C6EHQ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LIMK2
gene id: 30608:LIMK2
uniprot id: A0A8C5V3R3
uniprot id: A0A8C5Y7Q6
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

30608:SPICE1
gene id: 30608:SPICE1
uniprot id: A0A8B7HXP3
uniprot id: A0A8B7HXP6
uniprot id: A0A8B7HXQ1
uniprot id: A0A8B7HZS3
uniprot id: A0A8B7I0B7
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CEP120.
messages: centriole
messages: spindle

30608:THBS2
gene id: 30608:THBS2
uniprot id: A0A8B7X576
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:FUT7
gene id: 30608:FUT7
uniprot id: A0A8B7HQ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Membrane

30608:RARS2
gene id: 30608:RARS2
uniprot id: A0A8B7FDM5
uniprot id: A0A8B7FEH8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

30608:SLC28A3
gene id: 30608:SLC28A3
uniprot id: A0A8C5UWQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

30608:CLK1
gene id: 30608:CLK1
uniprot id: A0A8B7EJQ9
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:CDC25A
gene id: 30608:CDC25A
uniprot id: A0A8B7GT85
uniprot id: A0A8B7GTF3
uniprot id: A0A8B7GTG2
uniprot id: A0A8B7GV03
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

30608:SLC24A2
gene id: 30608:SLC24A2
uniprot id: A0A8B7GPW9
uniprot id: A0A8B7GQC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

30608:SCNM1
gene id: 30608:SCNM1
uniprot id: A0A8B7GKG0
names: Function
names: Subcellular Location Annotation
messages: Nucleus speckle
messages: Plays a role in alternative splicing of pre-mRNAs, possibly by contributing to the selection of non-consensus donor sites.
messages: nucleoplasm

30608:TMEM211
gene id: 30608:TMEM211
uniprot id: A0A8B7WTF5
names: Subcellular Location Annotation
messages: Membrane

30608:CRELD1
gene id: 30608:CRELD1
uniprot id: A0A8B7G3D8
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PARG
gene id: 30608:PARG
uniprot id: A0A8B7EXE7
uniprot id: A0A8B7EZA5
uniprot id: A0A8B7EZG4
names: Similarity
messages: Belongs to the poly(ADP-ribose) glycohydrolase family.

30608:LOC105872223
gene id: 30608:LOC105872223
uniprot id: A0A8B7GG22
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

30608:MDH2
gene id: 30608:MDH2
uniprot id: A0A8B7FZH9
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

30608:GRINA
gene id: 30608:GRINA
uniprot id: A0A8B7G246
names: Subcellular Location Annotation
messages: Membrane

30608:PATL2
gene id: 30608:PATL2
uniprot id: A0A8B7GH77
uniprot id: A0A8B7GH83
uniprot id: A0A8B7GHM0
uniprot id: A0A8B7X1K7
uniprot id: A0A8B7X1M9
uniprot id: A0A8B7X2U9
uniprot id: A0A8B7X3D1
names: Similarity
messages: Belongs to the PAT1 family.

30608:DRC1
gene id: 30608:DRC1
uniprot id: A0A8B7HZC0
uniprot id: A0A8C5VSE9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DRC1 family.
messages: Component of the nexin-dynein regulatory complex (N-DRC).
messages: cilium axoneme
messages: flagellum axoneme

30608:ODAM
gene id: 30608:ODAM
uniprot id: A0A8B7HTN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ODAM family.
messages: Cytoplasm
messages: Interacts (via C-terminus) with ARHGEF5.
messages: Nucleus
messages: Secreted
messages: Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface.

30608:INTS7
gene id: 30608:INTS7
uniprot id: A0A8B7HIH0
uniprot id: A0A8C5VLZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 7 family.
messages: Nucleus

30608:GRK3
gene id: 30608:GRK3
uniprot id: A0A8B7FSI5
uniprot id: A0A8B7FT30
uniprot id: A0A8B7FTF3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

30608:SLC7A10
gene id: 30608:SLC7A10
uniprot id: A0A8B7H2Z5
uniprot id: A0A8B7H2Z7
uniprot id: A0A8B7H2Z8
names: Subcellular Location Annotation
messages: Membrane

30608:GYS1
gene id: 30608:GYS1
uniprot id: A0A8B7FLU3
uniprot id: A0A8B7FM35
uniprot id: A0A8B7FM39
uniprot id: A0A8C5YD38
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

30608:DRD4
gene id: 30608:DRD4
uniprot id: A0A8B7X3B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SUSD2
gene id: 30608:SUSD2
uniprot id: A0A8B7F9V0
uniprot id: A0A8B7FA88
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105864756
gene id: 30608:LOC105864756
uniprot id: A0A8B7FID7
uniprot id: A0A8B7FIL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105879891
gene id: 30608:LOC105879891
uniprot id: A0A8B7HIH4
names: Similarity
messages: Belongs to the cystatin family.

30608:BBS5
gene id: 30608:BBS5
uniprot id: A0A8B7HJ05
uniprot id: A0A8C5VZW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BBS5 family.
messages: Membrane
messages: Part of BBSome complex, that contains BBS1, BBS2, BBS4, BBS5, BBS7, BBS8/TTC8, BBS9 and BBIP10.
messages: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for BBSome complex ciliary localization but not for the proper complex assembly.
messages: centriolar satellite
messages: cilium membrane

30608:CHRDL1
gene id: 30608:CHRDL1
uniprot id: A0A8B7FBE7
uniprot id: A0A8B7FBF9
uniprot id: A0A8B7FBG0
names: Subcellular Location Annotation
messages: Secreted

30608:ARRDC2
gene id: 30608:ARRDC2
uniprot id: A0A8B7WXR2
names: Similarity
messages: Belongs to the arrestin family.

30608:CREBBP
gene id: 30608:CREBBP
uniprot id: A0A8B7EV47
uniprot id: A0A8B7EV49
uniprot id: A0A8B7EV55
names: Subcellular Location Annotation
messages: Cytoplasm

30608:PES1
gene id: 30608:PES1
uniprot id: A0A8B7GAE3
uniprot id: A0A8B7GB51
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Chromosome
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome. Interacts with IRS1 and UBTF. May interact with MAP1B.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: Sumoylated.
messages: nucleolus
messages: nucleoplasm

30608:LOC105870765
gene id: 30608:LOC105870765
uniprot id: A0A8B7WSJ9
names: Similarity
messages: Belongs to the MHC class I family.

30608:RPL37A
gene id: 30608:RPL37A
uniprot id: A0A8C5XGW7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

30608:TCEANC2
gene id: 30608:TCEANC2
uniprot id: A0A8B7H5T4
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105871387
gene id: 30608:LOC105871387
uniprot id: A0A8C5UN94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105877255
gene id: 30608:LOC105877255
uniprot id: A0A8B7WZZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.
messages: centrosome

30608:HMGB3
gene id: 30608:HMGB3
uniprot id: A0A8B7EDG8
uniprot id: A0A8C5YHG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

30608:GRK5
gene id: 30608:GRK5
uniprot id: A0A8B7EIX8
uniprot id: A0A8B7EJA4
uniprot id: A0A8B7ELB2
uniprot id: A0A8C5XXN0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

30608:NRTN
gene id: 30608:NRTN
uniprot id: A0A8B7G4J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

30608:ELOA
gene id: 30608:ELOA
uniprot id: A0A8B7WMI9
names: Subcellular Location Annotation
messages: Nucleus

30608:CDK20
gene id: 30608:CDK20
uniprot id: A0A8C5XRS1
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:TEX13C
gene id: 30608:TEX13C
uniprot id: A0A8B7G485
names: Similarity
messages: Belongs to the TEX13 family.

30608:LOC105862113
gene id: 30608:LOC105862113
uniprot id: A0A8B7F6Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MED19
gene id: 30608:MED19
uniprot id: A0A8B7FB49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

30608:LOC105862746
gene id: 30608:LOC105862746
uniprot id: A0A8B7F9J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

30608:PACS1
gene id: 30608:PACS1
uniprot id: A0A8B7FUS2
uniprot id: A0A8B7FVH6
names: Similarity
messages: Belongs to the PACS family.

30608:LOC105878590
gene id: 30608:LOC105878590
uniprot id: A0A8C5W3T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex).
messages: Belongs to the UQCC3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology.

30608:RNF182
gene id: 30608:RNF182
uniprot id: A0A8B7FKJ5
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with ATP6V0C.
messages: Membrane

30608:LALBA
gene id: 30608:LALBA
uniprot id: A0A8B7GDB2
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.

30608:PAQR4
gene id: 30608:PAQR4
uniprot id: A0A8C5YF69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

30608:TRAPPC1
gene id: 30608:TRAPPC1
uniprot id: A0A8B7H6M5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

30608:LOC105885896
gene id: 30608:LOC105885896
uniprot id: A0A8B7X0C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornifin (SPRR) family.
messages: Cytoplasm

30608:PPP2R3C
gene id: 30608:PPP2R3C
uniprot id: A0A8B7ECM5
uniprot id: A0A8B7EEV5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:LOC105883367
gene id: 30608:LOC105883367
uniprot id: A0A8B7HX15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MDN1
gene id: 30608:MDN1
uniprot id: A0A8B7X4H8
uniprot id: A0A8B7X532
uniprot id: A0A8B7X679
uniprot id: A0A8B7X6A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the midasin family.
messages: Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits.
messages: Nucleus
messages: nucleolus
messages: nucleoplasm

30608:LOC105864534
gene id: 30608:LOC105864534
uniprot id: A0A8B7FIS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:FOXC1
gene id: 30608:FOXC1
uniprot id: A0A8B7GMZ4
names: Subcellular Location Annotation
messages: Nucleus

30608:ADAMTS12
gene id: 30608:ADAMTS12
uniprot id: A0A8B7XCV1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:ULK1
gene id: 30608:ULK1
uniprot id: A0A8C5W8M9
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
messages: Serine/threonine-protein kinase involved in autophagy in response to starvation.

30608:NT5E
gene id: 30608:NT5E
uniprot id: A0A8B7F7K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-nucleotidase family.
messages: Membrane

30608:LOC105875886
gene id: 30608:LOC105875886
uniprot id: A0A8B7GYK6
uniprot id: A0A8B7GYQ9
uniprot id: A0A8B7H0I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

30608:KIAA1024L
gene id: 30608:KIAA1024L
uniprot id: A0A8B7EQG0
names: Similarity
messages: Belongs to the MINAR family.

30608:WNT7A
gene id: 30608:WNT7A
uniprot id: A0A8B7FHF2
uniprot id: A0A8B7FIQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

30608:TRNAU1AP
gene id: 30608:TRNAU1AP
uniprot id: A0A8B7FDI3
uniprot id: A0A8C5VKC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TRSPAP family.
messages: Cytoplasm
messages: Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis.
messages: Nucleus

30608:CTNS
gene id: 30608:CTNS
uniprot id: A0A8B7HD51
uniprot id: A0A8B7HFL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cystinosin family.
messages: Membrane

30608:EPHB2
gene id: 30608:EPHB2
uniprot id: A0A8B7WMT3
uniprot id: A0A8B7WNY9
names: Subcellular Location Annotation
messages: Membrane

30608:ILVBL
gene id: 30608:ILVBL
uniprot id: A0A8B7FWV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPP enzyme family.
messages: Membrane

30608:LOC109730489
gene id: 30608:LOC109730489
uniprot id: A0A8B7X333
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MOB1A
gene id: 30608:MOB1A
uniprot id: A0A8B7I0K0
uniprot id: A0A8B7I0K7
uniprot id: A0A8B7I2P3
uniprot id: A0A8B7X260
names: Similarity
messages: Belongs to the MOB1/phocein family.

30608:PMF1
gene id: 30608:PMF1
uniprot id: A0A8B7GJU7
uniprot id: A0A8B7GJU9
uniprot id: A0A8C5UQU5
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

30608:LOC105879700
gene id: 30608:LOC105879700
uniprot id: A0A8B7HEZ1
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:UNG
gene id: 30608:UNG
uniprot id: A0A8B7FT56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Monomer. Interacts with FAM72A.
messages: Nucleus

30608:ART3
gene id: 30608:ART3
uniprot id: A0A8B7EWF7
uniprot id: A0A8B7EWG7
uniprot id: A0A8B7EWI8
uniprot id: A0A8B7EWJ4
uniprot id: A0A8B7EWJ7
uniprot id: A0A8B7EYE3
uniprot id: A0A8B7EYF1
uniprot id: A0A8B7EYH7
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

30608:LOC105864760
gene id: 30608:LOC105864760
uniprot id: A0A8B7FJU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105870502
gene id: 30608:LOC105870502
uniprot id: A0A8B7G9B5
names: Subcellular Location Annotation
messages: Membrane

30608:SNW1
gene id: 30608:SNW1
uniprot id: A0A8B7EVL7
uniprot id: A0A8B7EVM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNW family.
messages: Identified in the spliceosome C complex.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

30608:NUBP2
gene id: 30608:NUBP2
uniprot id: A0A8B7EWU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. Interacts with KIFC1.
messages: Nucleus
messages: centrosome

30608:FABP5
gene id: 30608:FABP5
uniprot id: A0A8C5VNT4
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

30608:IL19
gene id: 30608:IL19
uniprot id: A0A8C5UVA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

30608:RPS29
gene id: 30608:RPS29
uniprot id: A0A8C5YBP3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Component of the 40S small ribosomal subunit.

30608:LOC105859567
gene id: 30608:LOC105859567
uniprot id: A0A8B7EUG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:GIPC3
gene id: 30608:GIPC3
uniprot id: A0A8B7GNS7
names: Similarity
messages: Belongs to the GIPC family.

30608:KIAA1324
gene id: 30608:KIAA1324
uniprot id: A0A8B7FGM8
uniprot id: A0A8C5V3U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

30608:LOC105859508
gene id: 30608:LOC105859508
uniprot id: A0A8B7EU91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

30608:LOC105861542
gene id: 30608:LOC105861542
uniprot id: A0A8B7F4E4
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:TFCP2L1
gene id: 30608:TFCP2L1
uniprot id: A0A8B7F671
uniprot id: A0A8C5Y9L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

30608:LOC105858729
gene id: 30608:LOC105858729
uniprot id: A0A8B7ER05
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:KCNG3
gene id: 30608:KCNG3
uniprot id: A0A8B7FSP7
uniprot id: A0A8B7FSQ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:CRYBG3
gene id: 30608:CRYBG3
uniprot id: A0A8B7GHW5
uniprot id: A0A8B7GI98
uniprot id: A0A8C5YHM9
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

30608:C5AR1
gene id: 30608:C5AR1
uniprot id: A0A8C5YDN8
names: Subcellular Location Annotation
messages: Cell membrane

30608:TMEM63A
gene id: 30608:TMEM63A
uniprot id: A0A8B7FEK8
uniprot id: A0A8B7FEU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

30608:TRIM32
gene id: 30608:TRIM32
uniprot id: A0A8B7GNQ0
names: Similarity
messages: Belongs to the TRIM/RBCC family.

30608:LOC109730717
gene id: 30608:LOC109730717
uniprot id: A0A8B7X5L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:GDF3
gene id: 30608:GDF3
uniprot id: A0A8B7H8T9
names: Similarity
messages: Belongs to the TGF-beta family.

30608:LOC105864333
gene id: 30608:LOC105864333
uniprot id: A0A8B7FI00
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

30608:IVL
gene id: 30608:IVL
uniprot id: A0A8B7I9Z4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the involucrin family.
messages: Cytoplasm
messages: Directly or indirectly cross-linked to cornifelin (CNFN).
messages: Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.
messages: Substrate of transglutaminase.

30608:GABRB3
gene id: 30608:GABRB3
uniprot id: A0A8C5UHT2
uniprot id: A0A8C5Y744
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:SLC1A5
gene id: 30608:SLC1A5
uniprot id: A0A8C6EIU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

30608:LOC105883379
gene id: 30608:LOC105883379
uniprot id: A0A8B7HUX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105883500
gene id: 30608:LOC105883500
uniprot id: A0A8B7HVF6
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105864596
gene id: 30608:LOC105864596
uniprot id: A0A8B7FHX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105883741
gene id: 30608:LOC105883741
uniprot id: A0A8B7WRS2
names: Similarity
messages: Belongs to the serpin family.

30608:PHKB
gene id: 30608:PHKB
uniprot id: A0A8B7GZW9
uniprot id: A0A8B7GZX0
uniprot id: A0A8B7H1W2
uniprot id: A0A8B7WSQ0
uniprot id: A0A8C5XXU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.

30608:CRH
gene id: 30608:CRH
uniprot id: A0A8B7EEH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

30608:AMBP
gene id: 30608:AMBP
uniprot id: A0A8B7GMI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Endoplasmic reticulum
messages: In the N-terminal section; belongs to the calycin superfamily. Lipocalin family.
messages: Kunitz-type serine protease inhibitor. Has high catalytic efficiency for F10/blood coagulation factor Xa and may act as an anticoagulant by inhibiting prothrombin activation. Inhibits trypsin and mast cell CMA1/chymase and tryptase proteases.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer. Also occurs as a complex with tryptase in mast cells.
messages: Nucleus membrane
messages: cytosol
messages: extracellular matrix

30608:LTBP2
gene id: 30608:LTBP2
uniprot id: A0A8B7X0N6
uniprot id: A0A8B7X0N7
uniprot id: A0A8C5W1X0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:MPI
gene id: 30608:MPI
uniprot id: A0A8B7E9Q3
uniprot id: A0A8B7E9X4
uniprot id: A0A8B7EAE2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

30608:DLGAP5
gene id: 30608:DLGAP5
uniprot id: A0A8B7X1Y2
names: Similarity
messages: Belongs to the SAPAP family.

30608:MGMT
gene id: 30608:MGMT
uniprot id: A0A8B7HIU3
uniprot id: A0A8C5Y7J9
names: Function
names: Similarity
messages: Belongs to the MGMT family.
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

30608:FAM69C
gene id: 30608:FAM69C
uniprot id: A0A8B7WSJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

30608:MYO5A
gene id: 30608:MYO5A
uniprot id: A0A8B7G8Y7
uniprot id: A0A8B7G8Z0
uniprot id: A0A8B7G8Z1
uniprot id: A0A8B7G9L8
uniprot id: A0A8B7GA28
uniprot id: A0A8B7GA32
uniprot id: A0A8B7X343
uniprot id: A0A8C5V174
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SLC7A8
gene id: 30608:SLC7A8
uniprot id: A0A8C5URL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Membrane

30608:EMC1
gene id: 30608:EMC1
uniprot id: A0A8B7HY46
uniprot id: A0A8B7HY57
uniprot id: A0A8B7I071
uniprot id: A0A8B7I0U6
uniprot id: A0A8C5UTA0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:GRB10
gene id: 30608:GRB10
uniprot id: A0A8B7EAZ3
uniprot id: A0A8B7EB24
uniprot id: A0A8B7EBB0
uniprot id: A0A8B7EBC0
uniprot id: A0A8B7EDQ1
uniprot id: A0A8C5W4R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

30608:UCP1
gene id: 30608:UCP1
uniprot id: A0A8B7HNI5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: May undergo ubiquitin-mediated proteasomal degradation.
messages: Membrane
messages: Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates in non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance. Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane. However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent transport of protons activated by LCFAs. Thereby, dissipates the mitochondrial proton gradient and converts the energy of substrate oxydation into heat instead of ATP. Regulates the production of reactive oxygen species/ROS by mitochondria.
messages: Mitochondrion inner membrane

30608:NDUFAB1
gene id: 30608:NDUFAB1
uniprot id: A0A8C5UTQ4
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

30608:GNAL
gene id: 30608:GNAL
uniprot id: A0A8B7WRG5
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

30608:LHFPL1
gene id: 30608:LHFPL1
uniprot id: A0A8B7FAJ3
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105855930
gene id: 30608:LOC105855930
uniprot id: A0A8B7EDZ3
uniprot id: A0A8B7EEJ4
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Homotetramer.

30608:TNK2
gene id: 30608:TNK2
uniprot id: A0A8B7HFH8
uniprot id: A0A8B7HFH9
uniprot id: A0A8B7HFK8
uniprot id: A0A8B7HFL3
uniprot id: A0A8B7HG29
uniprot id: A0A8B7HI61
uniprot id: A0A8B7HI67
uniprot id: A0A8C5YJT1
uniprot id: A0A8C5YKZ9
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus

30608:CD200
gene id: 30608:CD200
uniprot id: A0A8B7HXM4
uniprot id: A0A8B7I070
uniprot id: A0A8B7X5V9
uniprot id: A0A8B7X7M7
uniprot id: A0A8C5YIV4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:KCNS1
gene id: 30608:KCNS1
uniprot id: A0A8B7HFM9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:LOC105864471
gene id: 30608:LOC105864471
uniprot id: A0A8B7FIG5
names: Subcellular Location Annotation
messages: Membrane

30608:EFNB3
gene id: 30608:EFNB3
uniprot id: A0A8B7H7H4
uniprot id: A0A8C5XI11
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:DHTKD1
gene id: 30608:DHTKD1
uniprot id: A0A8C5UKC4
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

30608:HSDL1
gene id: 30608:HSDL1
uniprot id: A0A8C5XX06
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:LOC105857570
gene id: 30608:LOC105857570
uniprot id: A0A8B7EMA4
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

30608:ANPEP
gene id: 30608:ANPEP
uniprot id: A0A8B7XB01
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

30608:CCDC90B
gene id: 30608:CCDC90B
uniprot id: A0A8B7EBX5
uniprot id: A0A8C5VSA8
names: Similarity
messages: Belongs to the CCDC90 family.

30608:COG6
gene id: 30608:COG6
uniprot id: A0A8B7EUM6
uniprot id: A0A8C5Y2J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COG6 family.
messages: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
messages: Golgi apparatus membrane
messages: Membrane
messages: Required for normal Golgi function.

30608:LOC105858681
gene id: 30608:LOC105858681
uniprot id: A0A8B7EQU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

30608:AGA
gene id: 30608:AGA
uniprot id: A0A8C5XZF2
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

30608:HIGD1B
gene id: 30608:HIGD1B
uniprot id: A0A8C5XWV5
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

30608:TNFRSF6B
gene id: 30608:TNFRSF6B
uniprot id: A0A8B7GXU8
uniprot id: A0A8B7GXW5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:HTR6
gene id: 30608:HTR6
uniprot id: A0A8C5WB41
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:ATF4
gene id: 30608:ATF4
uniprot id: A0A8C5Y6Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

30608:RELL1
gene id: 30608:RELL1
uniprot id: A0A8B7X2G1
uniprot id: A0A8B7X2G4
uniprot id: A0A8B7X2G6
uniprot id: A0A8B7X2G9
uniprot id: A0A8B7X301
uniprot id: A0A8B7X3U9
uniprot id: A0A8B7X3V4
uniprot id: A0A8B7X480
names: Similarity
messages: Belongs to the RELT family.

30608:LOC105871814
gene id: 30608:LOC105871814
uniprot id: A0A8B7GDW3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

30608:CDX1
gene id: 30608:CDX1
uniprot id: A0A8B7EQ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

30608:NPTX1
gene id: 30608:NPTX1
uniprot id: A0A8B7I2K2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105859392
gene id: 30608:LOC105859392
uniprot id: A0A8B7ETU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105872888
gene id: 30608:LOC105872888
uniprot id: A0A8B7WST4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:TSPAN9
gene id: 30608:TSPAN9
uniprot id: A0A8B7HM04
uniprot id: A0A8B7HM05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

30608:RNF20
gene id: 30608:RNF20
uniprot id: A0A8B7GMT6
uniprot id: A0A8B7GMU0
uniprot id: A0A8B7GN47
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BRE1 family.
messages: Component of the RNF20/40 complex (also known as BRE1 complex) probably composed of 2 copies of RNF20/BRE1A and 2 copies of RNF40/BRE1B. Interacts with UBE2E1/UBCH6.
messages: Nucleus

30608:IFITM5
gene id: 30608:IFITM5
uniprot id: A0A8C5UTX0
names: Similarity
messages: Belongs to the CD225/Dispanin family.

30608:LOC105864451
gene id: 30608:LOC105864451
uniprot id: A0A8B7FIE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:BDH1
gene id: 30608:BDH1
uniprot id: A0A8B7HFV4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:PRKAR2B
gene id: 30608:PRKAR2B
uniprot id: A0A8C5VVW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

30608:NAMPT
gene id: 30608:NAMPT
uniprot id: A0A8B7F207
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

30608:CHRNB4
gene id: 30608:CHRNB4
uniprot id: A0A8B7ELX9
uniprot id: A0A8B7X1W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:CTNNB1
gene id: 30608:CTNNB1
uniprot id: A0A8B7GSQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: adherens junction

30608:SLC8A1
gene id: 30608:SLC8A1
uniprot id: A0A8B7I0A0
uniprot id: A0A8B7I0A9
uniprot id: A0A8B7I0B0
uniprot id: A0A8B7I0B1
uniprot id: A0A8B7I0B5
uniprot id: A0A8B7I0B6
uniprot id: A0A8B7I2E2
uniprot id: A0A8B7I2E7
uniprot id: A0A8B7I319
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

30608:TRAPPC6A
gene id: 30608:TRAPPC6A
uniprot id: A0A8B7G433
uniprot id: A0A8B7G5F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

30608:SMIM8
gene id: 30608:SMIM8
uniprot id: A0A8B7FER7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM8 family.
messages: Membrane

30608:STX17
gene id: 30608:STX17
uniprot id: A0A8B7GMZ0
names: Similarity
messages: Belongs to the syntaxin family.

30608:TBL1X
gene id: 30608:TBL1X
uniprot id: A0A8B7HLI7
uniprot id: A0A8B7WYX5
uniprot id: A0A8B7WZG8
uniprot id: A0A8B7X0N8
names: Similarity
messages: Belongs to the WD repeat EBI family.

30608:ZSCAN30
gene id: 30608:ZSCAN30
uniprot id: A0A8B7ER59
uniprot id: A0A8B7ER62
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105885542
gene id: 30608:LOC105885542
uniprot id: A0A8B7I892
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PPTC7
gene id: 30608:PPTC7
uniprot id: A0A8B7HL78
names: Similarity
messages: Belongs to the PP2C family.

30608:PLBD1
gene id: 30608:PLBD1
uniprot id: A0A8C5V330
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

30608:C18H20orf27
gene id: 30608:C18H20orf27
uniprot id: A0A8B7FPF4
uniprot id: A0A8C5UN96
names: Similarity
messages: Belongs to the UPF0687 family.

30608:CD48
gene id: 30608:CD48
uniprot id: A0A8B7F9G6
uniprot id: A0A8C5W905
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105855631
gene id: 30608:LOC105855631
uniprot id: A0A8C5UV57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

30608:TNF
gene id: 30608:TNF
uniprot id: A0A8B7ENJ8
uniprot id: A0A8B7ENP6
uniprot id: A0A8B7EQ28
uniprot id: A0A8B7EQP5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tumor necrosis factor family.
messages: Cell membrane
messages: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance. Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6.
messages: Homotrimer. Interacts with SPPL2B.
messages: Membrane
messages: O-glycosylated; glycans contain galactose, N-acetylgalactosamine and N-acetylneuraminic acid.
messages: Secreted
messages: The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
messages: The membrane form, but not the soluble form, is phosphorylated on serine residues. Dephosphorylation of the membrane form occurs by binding to soluble TNFRSF1A/TNFR1.
messages: The soluble form derives from the membrane form by proteolytic processing. The membrane-bound form is further proteolytically processed by SPPL2A or SPPL2B through regulated intramembrane proteolysis producing TNF intracellular domains (ICD1 and ICD2) released in the cytosol and TNF C-domain 1 and C-domain 2 secreted into the extracellular space.

30608:FREM2
gene id: 30608:FREM2
uniprot id: A0A8B7XF66
names: Similarity
messages: Belongs to the FRAS1 family.

30608:SH3RF3
gene id: 30608:SH3RF3
uniprot id: A0A8B7EFP8
names: Similarity
messages: Belongs to the SH3RF family.

30608:TMCC3
gene id: 30608:TMCC3
uniprot id: A0A8B7H3A6
uniprot id: A0A8B7H3G1
uniprot id: A0A8B7H5H1
uniprot id: A0A8B7X8U4
names: Similarity
messages: Belongs to the TEX28 family.

30608:RPSA
gene id: 30608:RPSA
uniprot id: A0A8C5YFG1
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK. The mature dimeric form interacts with PPP1R16B (via its fourth ankyrin repeat). Interacts with PPP1CA only in the presence of PPP1R16B.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

30608:TNRC6A
gene id: 30608:TNRC6A
uniprot id: A0A8B7HEY4
uniprot id: A0A8B7HF07
uniprot id: A0A8B7WNW5
uniprot id: A0A8B7WNX6
uniprot id: A0A8B7WQ69
uniprot id: A0A8C5XKF3
uniprot id: A0A8C6EFH9
names: Similarity
messages: Belongs to the GW182 family.

30608:GABRG3
gene id: 30608:GABRG3
uniprot id: A0A8B7G0G9
uniprot id: A0A8C5XAR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:INPP4A
gene id: 30608:INPP4A
uniprot id: A0A8B7HWB4
uniprot id: A0A8B7HWB8
uniprot id: A0A8B7HWB9
uniprot id: A0A8B7HWC2
uniprot id: A0A8B7HWC4
uniprot id: A0A8B7HWC6
uniprot id: A0A8B7HWC9
uniprot id: A0A8B7HWD0
uniprot id: A0A8B7HWD1
uniprot id: A0A8B7HWD5
uniprot id: A0A8B7HWD9
uniprot id: A0A8B7HWE3
uniprot id: A0A8B7HYF6
uniprot id: A0A8B7HYG5
uniprot id: A0A8B7HYS0
uniprot id: A0A8B7HYS6
uniprot id: A0A8C5W4H1
uniprot id: A0A8C5WAH5
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

30608:SLC33A1
gene id: 30608:SLC33A1
uniprot id: A0A8C5YHG2
names: Subcellular Location Annotation
messages: Membrane

30608:UPF3B
gene id: 30608:UPF3B
uniprot id: A0A8B7EJ96
names: Similarity
messages: Belongs to the RENT3 family.

30608:CPNE7
gene id: 30608:CPNE7
uniprot id: A0A8B7WUE4
uniprot id: A0A8C5UWC9
names: Similarity
messages: Belongs to the copine family.

30608:SPTY2D1
gene id: 30608:SPTY2D1
uniprot id: A0A8C5VAT7
names: Similarity
messages: Belongs to the SPT2 family.

30608:CTLA4
gene id: 30608:CTLA4
uniprot id: A0A8C5VE98
uniprot id: A0A8C6EJZ6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
messages: Membrane

30608:EPHA10
gene id: 30608:EPHA10
uniprot id: A0A8C5UYU7
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105864424
gene id: 30608:LOC105864424
uniprot id: A0A8B7FH21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105882148
gene id: 30608:LOC105882148
uniprot id: A0A8B7WWI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

30608:CRYBB3
gene id: 30608:CRYBB3
uniprot id: A0A8B7FTF1
uniprot id: A0A8C5V2P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

30608:TTN
gene id: 30608:TTN
uniprot id: A0A8B7HTD9
uniprot id: A0A8B7HTE5
uniprot id: A0A8B7HTF1
uniprot id: A0A8B7HTF7
uniprot id: A0A8B7HVF7
uniprot id: A0A8B7HVM3
uniprot id: A0A8B7X7Z3
uniprot id: A0A8B7X7Z7
uniprot id: A0A8B7X801
uniprot id: A0A8B7X803
uniprot id: A0A8B7X809
uniprot id: A0A8B7X810
uniprot id: A0A8B7X817
uniprot id: A0A8B7X818
uniprot id: A0A8B7X826
uniprot id: A0A8B7X827
uniprot id: A0A8B7X834
uniprot id: A0A8B7X836
uniprot id: A0A8B7X841
uniprot id: A0A8B7X843
uniprot id: A0A8B7X848
uniprot id: A0A8B7X849
uniprot id: A0A8B7X8M9
uniprot id: A0A8B7X8N7
uniprot id: A0A8B7X8P4
uniprot id: A0A8B7X8Q3
uniprot id: A0A8B7X8R0
uniprot id: A0A8B7X8R8
uniprot id: A0A8B7X8S7
uniprot id: A0A8B7X8T5
uniprot id: A0A8B7X9M8
uniprot id: A0A8B7X9N7
uniprot id: A0A8B7X9P3
uniprot id: A0A8B7X9Q2
uniprot id: A0A8B7X9Q9
uniprot id: A0A8B7X9R7
uniprot id: A0A8B7X9S4
uniprot id: A0A8B7X9T3
uniprot id: A0A8B7X9T8
uniprot id: A0A8B7X9Z2
uniprot id: A0A8B7XA01
uniprot id: A0A8B7XA10
uniprot id: A0A8B7XA17
uniprot id: A0A8B7XA24
uniprot id: A0A8B7XA30
uniprot id: A0A8B7XA40
uniprot id: A0A8B7XA46
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

30608:OSBPL5
gene id: 30608:OSBPL5
uniprot id: A0A8C5VB49
names: Similarity
messages: Belongs to the OSBP family.

30608:SLC25A19
gene id: 30608:SLC25A19
uniprot id: A0A8B7HBS2
uniprot id: A0A8B7HEE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:LOC105859167
gene id: 30608:LOC105859167
uniprot id: A0A8B7EUU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

30608:NTF4
gene id: 30608:NTF4
uniprot id: A0A8B7FM51
names: Similarity
messages: Belongs to the NGF-beta family.

30608:LOC105879993
gene id: 30608:LOC105879993
uniprot id: A0A8C5VIG6
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:LOC105879971
gene id: 30608:LOC105879971
uniprot id: A0A8C5Y1I4
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

30608:WNK2
gene id: 30608:WNK2
uniprot id: A0A8B7F4L3
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

30608:IRF1
gene id: 30608:IRF1
uniprot id: A0A8B7G5Q9
uniprot id: A0A8B7G6H7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

30608:DCTN2
gene id: 30608:DCTN2
uniprot id: A0A8B7H7N1
uniprot id: A0A8B7H7N2
uniprot id: A0A8B7X6E6
uniprot id: A0A8C5VUA2
uniprot id: A0A8C5WB53
names: Function
names: Similarity
messages: Belongs to the dynactin subunit 2 family.
messages: Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.

30608:SEPT7
gene id: 30608:SEPT7
uniprot id: A0A8B7H8P7
uniprot id: A0A8B7H8Q3
uniprot id: A0A8B7H8Q4
uniprot id: A0A8B7HBC9
uniprot id: A0A8B7XCF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Filament-forming cytoskeletal GTPase.
messages: Midbody
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: cilium axoneme
messages: flagellum
messages: kinetochore
messages: spindle

30608:TANGO6
gene id: 30608:TANGO6
uniprot id: A0A8B7WST6
names: Similarity
messages: Belongs to the Tango6 family.

30608:LOC105869853
gene id: 30608:LOC105869853
uniprot id: A0A8B7G5G4
uniprot id: A0A8B7G6N6
names: Subcellular Location Annotation
messages: Membrane

30608:VDR
gene id: 30608:VDR
uniprot id: A0A8B7FMY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Cytoplasm
messages: Nucleus

30608:LOC105864549
gene id: 30608:LOC105864549
uniprot id: A0A8B7FHH5
uniprot id: A0A8B7FHI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:GTPBP8
gene id: 30608:GTPBP8
uniprot id: A0A8B7HXM8
uniprot id: A0A8B7HXN7
uniprot id: A0A8B7I095
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.

30608:GTF2F2
gene id: 30608:GTF2F2
uniprot id: A0A8C5XP23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

30608:ELMO2
gene id: 30608:ELMO2
uniprot id: A0A8B7ETD1
uniprot id: A0A8B7ETD3
uniprot id: A0A8B7ETD7
uniprot id: A0A8B7ETD8
uniprot id: A0A8B7EVD3
uniprot id: A0A8C5V1A8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

30608:LOC105862783
gene id: 30608:LOC105862783
uniprot id: A0A8B7F9P4
uniprot id: A0A8C5V059
names: Similarity
names: Subunit
messages: Belongs to the GST superfamily. Theta family.
messages: Homodimer.

30608:RPL34
gene id: 30608:RPL34
uniprot id: A0A8B7GGT4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

30608:DOCK10
gene id: 30608:DOCK10
uniprot id: A0A8B7F9T6
uniprot id: A0A8B7F9U0
uniprot id: A0A8B7F9U3
uniprot id: A0A8B7F9U4
uniprot id: A0A8B7F9U5
uniprot id: A0A8B7F9U9
uniprot id: A0A8B7F9V5
uniprot id: A0A8B7F9Y1
uniprot id: A0A8B7F9Y6
uniprot id: A0A8B7F9Z3
uniprot id: A0A8B7FAD0
uniprot id: A0A8B7FAD8
uniprot id: A0A8B7X7J7
uniprot id: A0A8B7X7K2
uniprot id: A0A8B7X7K3
uniprot id: A0A8B7X887
uniprot id: A0A8B7X894
uniprot id: A0A8B7X986
uniprot id: A0A8B7X993
uniprot id: A0A8B7X9K5
uniprot id: A0A8B7X9L2
uniprot id: A0A8C5VU85
names: Similarity
messages: Belongs to the DOCK family.

30608:LSM1
gene id: 30608:LSM1
uniprot id: A0A8B7G7V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: Interacts with SLBP; interaction with SLBP occurs when histone mRNA is being rapidly degraded during the S phase. LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.

30608:DAPK2
gene id: 30608:DAPK2
uniprot id: A0A8B7FYF9
uniprot id: A0A8C5XDG0
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:TMPRSS5
gene id: 30608:TMPRSS5
uniprot id: A0A8B7FJJ8
uniprot id: A0A8B7FJK2
uniprot id: A0A8B7FJK5
uniprot id: A0A8B7FJN6
uniprot id: A0A8B7FJS6
uniprot id: A0A8B7FKZ7
uniprot id: A0A8B7FL02
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:CD180
gene id: 30608:CD180
uniprot id: A0A8C5Y5W2
names: Similarity
messages: Belongs to the Toll-like receptor family.

30608:TUBAL3
gene id: 30608:TUBAL3
uniprot id: A0A8B7EP20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

30608:ZC3HAV1
gene id: 30608:ZC3HAV1
uniprot id: A0A8B7GKD4
uniprot id: A0A8B7GKP7
uniprot id: A0A8B7GL04
uniprot id: A0A8B7GLJ3
names: Similarity
messages: Belongs to the ARTD/PARP family.

30608:PLXNA3
gene id: 30608:PLXNA3
uniprot id: A0A8B7FW97
uniprot id: A0A8B7FWA1
uniprot id: A0A8B7FWG6
uniprot id: A0A8B7FX85
uniprot id: A0A8B7FX89
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LOC105863667
gene id: 30608:LOC105863667
uniprot id: A0A8B7FE41
uniprot id: A0A8B7FE48
uniprot id: A0A8B7FEA7
uniprot id: A0A8B7FF13
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

30608:LOC105865720
gene id: 30608:LOC105865720
uniprot id: A0A8B7FMI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PPP1CA
gene id: 30608:PPP1CA
uniprot id: A0A8C5VA47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cytoplasm
messages: nucleolus
messages: nucleoplasm

30608:LOC105867593
gene id: 30608:LOC105867593
uniprot id: A0A8B7FVE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative pheromone receptor.

30608:LPGAT1
gene id: 30608:LPGAT1
uniprot id: A0A8B7HIH5
uniprot id: A0A8B7HIH8
uniprot id: A0A8B7HIJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Endoplasmic reticulum membrane

30608:LAPTM4A
gene id: 30608:LAPTM4A
uniprot id: A0A8B7HY81
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

30608:DPH5
gene id: 30608:DPH5
uniprot id: A0A8C5XC01
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

30608:IL17B
gene id: 30608:IL17B
uniprot id: A0A8B7ES16
uniprot id: A0A8B7WWX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

30608:DHRS7
gene id: 30608:DHRS7
uniprot id: A0A8B7HV22
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:SLC25A15
gene id: 30608:SLC25A15
uniprot id: A0A8B7FX45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:HIGD1A
gene id: 30608:HIGD1A
uniprot id: A0A8C6ELP8
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

30608:STK39
gene id: 30608:STK39
uniprot id: A0A8B7X8A7
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

30608:LOC105883661
gene id: 30608:LOC105883661
uniprot id: A0A8C5USY9
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

30608:LOC105884125
gene id: 30608:LOC105884125
uniprot id: A0A8B7HYH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105878283
gene id: 30608:LOC105878283
uniprot id: A0A8B7H8V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

30608:NPRL2
gene id: 30608:NPRL2
uniprot id: A0A8B7WKZ0
uniprot id: A0A8C5XET8
names: Similarity
messages: Belongs to the NPR2 family.

30608:GLYATL2
gene id: 30608:GLYATL2
uniprot id: A0A8B7FB77
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

30608:ZNF532
gene id: 30608:ZNF532
uniprot id: A0A8B7WRP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: May be involved in transcriptional regulation.
messages: Nucleus

30608:CLUAP1
gene id: 30608:CLUAP1
uniprot id: A0A8B7EX79
uniprot id: A0A8B7EX81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

30608:GPR83
gene id: 30608:GPR83
uniprot id: A0A8C5XGU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:DDB1
gene id: 30608:DDB1
uniprot id: A0A8C5V863
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDB1 family.
messages: Component of complexes involved in DNA repair and protein ubiquitination. May play a role in the regulation of the circadian clock.
messages: Component of the UV-DDB complex.
messages: Nucleus
messages: The core of the protein consists of three WD40 beta-propeller domains.

30608:LOC105856887
gene id: 30608:LOC105856887
uniprot id: A0A8B7EII1
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

30608:YPEL4
gene id: 30608:YPEL4
uniprot id: A0A8B7FB48
names: Similarity
messages: Belongs to the yippee family.

30608:PPP6C
gene id: 30608:PPP6C
uniprot id: A0A8B7GV80
names: Similarity
messages: Belongs to the PPP phosphatase family.

30608:FPR2
gene id: 30608:FPR2
uniprot id: A0A8B7HSP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CAPN14
gene id: 30608:CAPN14
uniprot id: A0A8B7I1Z7
names: Similarity
messages: Belongs to the peptidase C2 family.

30608:LOC105861247
gene id: 30608:LOC105861247
uniprot id: A0A8B7F2H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CRB2
gene id: 30608:CRB2
uniprot id: A0A8B7GV14
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105884045
gene id: 30608:LOC105884045
uniprot id: A0A8B7HY88
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

30608:PPP1R2
gene id: 30608:PPP1R2
uniprot id: A0A8B7HFU9
uniprot id: A0A8B7HHZ3
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 2 family.

30608:CHD4
gene id: 30608:CHD4
uniprot id: A0A8B7G1M1
uniprot id: A0A8B7G1M7
uniprot id: A0A8B7G322
uniprot id: A0A8B7X674
uniprot id: A0A8B7X7X9
uniprot id: A0A8B7X867
uniprot id: A0A8C5URY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

30608:GNS
gene id: 30608:GNS
uniprot id: A0A8C5XJ12
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

30608:NAPG
gene id: 30608:NAPG
uniprot id: A0A8B7F1I5
uniprot id: A0A8C5XYP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

30608:SYP
gene id: 30608:SYP
uniprot id: A0A8C5UW55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane
messages: synaptic vesicle membrane
messages: synaptosome

30608:MGAT5B
gene id: 30608:MGAT5B
uniprot id: A0A8C5VK04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:HR
gene id: 30608:HR
uniprot id: A0A8B7EJ64
uniprot id: A0A8B7EKC4
uniprot id: A0A8B7ELK0
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105871131
gene id: 30608:LOC105871131
uniprot id: A0A8B7GB45
uniprot id: A0A8B7GBL0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:MX1
gene id: 30608:MX1
uniprot id: A0A8B7WYD9
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

30608:ILK
gene id: 30608:ILK
uniprot id: A0A8B7HV54
uniprot id: A0A8C5VPU9
uniprot id: A0A8C5Y2J2
names: Subcellular Location Annotation
messages: focal adhesion
messages: lamellipodium
messages: sarcomere

30608:TSPO
gene id: 30608:TSPO
uniprot id: A0A8B7X8A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane
messages: Mitochondrion membrane

30608:MYO7B
gene id: 30608:MYO7B
uniprot id: A0A8B7EKT9
uniprot id: A0A8B7X8Q7
uniprot id: A0A8C5XJQ4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

30608:LOC105871058
gene id: 30608:LOC105871058
uniprot id: A0A8B7GAR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

30608:CCDC181
gene id: 30608:CCDC181
uniprot id: A0A8B7HNP3
uniprot id: A0A8B7HNP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC181 family.
messages: Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
messages: cytoskeleton
messages: flagellum

30608:PSME2
gene id: 30608:PSME2
uniprot id: A0A8B7FRM1
names: Similarity
messages: Belongs to the PA28 family.

30608:LOC105858613
gene id: 30608:LOC105858613
uniprot id: A0A8B7EQM0
uniprot id: A0A8B7EQM3
uniprot id: A0A8B7ESQ5
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:FGD1
gene id: 30608:FGD1
uniprot id: A0A8B7F677
uniprot id: A0A8B7F679
uniprot id: A0A8B7F688
uniprot id: A0A8B7F6C3
names: Subcellular Location Annotation
messages: cytoskeleton

30608:LOC105879968
gene id: 30608:LOC105879968
uniprot id: A0A8B7HIU7
uniprot id: A0A8B7X4L1
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

30608:EMC9
gene id: 30608:EMC9
uniprot id: A0A8B7FR83
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

30608:AARS
gene id: 30608:AARS
uniprot id: A0A8B7GWK5
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: ISGylated.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

30608:DUSP13
gene id: 30608:DUSP13
uniprot id: A0A8B7G1A4
uniprot id: A0A8B7G1A8
uniprot id: A0A8B7G1B1
uniprot id: A0A8B7G1B6
uniprot id: A0A8B7G262
uniprot id: A0A8B7G267
uniprot id: A0A8B7G2N8
uniprot id: A0A8B7WLG7
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

30608:EP400
gene id: 30608:EP400
uniprot id: A0A8B7WTJ3
names: Subcellular Location Annotation
messages: Nucleus

30608:CMAS
gene id: 30608:CMAS
uniprot id: A0A8C5UNU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).
messages: Homotetramer; the active enzyme is formed by a dimer of dimers.

30608:MMP16
gene id: 30608:MMP16
uniprot id: A0A8B7H0U5
uniprot id: A0A8B7H105
uniprot id: A0A8C5VLJ5
names: Similarity
messages: Belongs to the peptidase M10A family.

30608:TSSK6
gene id: 30608:TSSK6
uniprot id: A0A8B7ER12
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:LOC105883673
gene id: 30608:LOC105883673
uniprot id: A0A8B7HWF4
uniprot id: A0A8C5W6L8
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

30608:TNFSF13B
gene id: 30608:TNFSF13B
uniprot id: A0A8B7FGD1
names: Similarity
messages: Belongs to the tumor necrosis factor family.

30608:LOC105855618
gene id: 30608:LOC105855618
uniprot id: A0A8B7XC86
names: Similarity
messages: Belongs to the FBPase class 1 family.

30608:PYGL
gene id: 30608:PYGL
uniprot id: A0A8B7FVS9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

30608:TRIM45
gene id: 30608:TRIM45
uniprot id: A0A8C5XH66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

30608:TCIRG1
gene id: 30608:TCIRG1
uniprot id: A0A8B7FUG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

30608:SCTR
gene id: 30608:SCTR
uniprot id: A0A8B7F9B8
uniprot id: A0A8B7F9C5
uniprot id: A0A8B7F9R7
uniprot id: A0A8B7F9T3
uniprot id: A0A8C5UNX2
names: Subcellular Location Annotation
messages: Membrane

30608:ZEB2
gene id: 30608:ZEB2
uniprot id: A0A8B7EXU5
uniprot id: A0A8B7EZP1
uniprot id: A0A8B7EZX6
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

30608:FAS
gene id: 30608:FAS
uniprot id: A0A8B7GD37
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

30608:ALOX12
gene id: 30608:ALOX12
uniprot id: A0A8B7WNH1
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ASB10
gene id: 30608:ASB10
uniprot id: A0A8B7HUA5
uniprot id: A0A8B7HWD7
uniprot id: A0A8C5XSD0
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

30608:GDF10
gene id: 30608:GDF10
uniprot id: A0A8B7FF63
names: Similarity
messages: Belongs to the TGF-beta family.

30608:SNX10
gene id: 30608:SNX10
uniprot id: A0A8B7GYP6
uniprot id: A0A8B7GYR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

30608:ASNA1
gene id: 30608:ASNA1
uniprot id: A0A8C5Y4R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homodimer. Component of a transmembrane domain recognition complex (TRC). Interacts with SERP1 and SEC61B. Interacts with WRB.
messages: nucleolus

30608:PPIL6
gene id: 30608:PPIL6
uniprot id: A0A8C5VGX0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

30608:SMARCA4
gene id: 30608:SMARCA4
uniprot id: A0A8B7I587
uniprot id: A0A8B7I791
uniprot id: A0A8B7I8E4
uniprot id: A0A8B7WW26
uniprot id: A0A8B7WW29
uniprot id: A0A8B7WWS5
uniprot id: A0A8B7WXS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

30608:LOC105878898
gene id: 30608:LOC105878898
uniprot id: A0A8B7WP79
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:NFE2L1
gene id: 30608:NFE2L1
uniprot id: A0A8B7GFX7
uniprot id: A0A8B7GG91
uniprot id: A0A8B7GG92
uniprot id: A0A8B7WNG9
uniprot id: A0A8B7WNH3
uniprot id: A0A8B7WNH5
uniprot id: A0A8B7WNK4
uniprot id: A0A8B7WPS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. CNC subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

30608:HSP90AA1
gene id: 30608:HSP90AA1
uniprot id: A0A8B7F1P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 90 family.
messages: Melanosome

30608:CUX1
gene id: 30608:CUX1
uniprot id: A0A8B7FXW5
uniprot id: A0A8B7FXX9
uniprot id: A0A8B7FY22
uniprot id: A0A8B7FY30
uniprot id: A0A8B7FYV6
uniprot id: A0A8B7FYW1
uniprot id: A0A8B7FYW5
uniprot id: A0A8B7FZ10
uniprot id: A0A8B7FZ15
uniprot id: A0A8B7WNM4
uniprot id: A0A8C5W8E4
uniprot id: A0A8C5XK47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASP family.
messages: Belongs to the CUT homeobox family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Nucleus

30608:YPEL2
gene id: 30608:YPEL2
uniprot id: A0A8B7GQ60
names: Similarity
messages: Belongs to the yippee family.

30608:LOC105868237
gene id: 30608:LOC105868237
uniprot id: A0A8B7FXS3
names: Subcellular Location Annotation
messages: Nucleus

30608:TMEM50A
gene id: 30608:TMEM50A
uniprot id: A0A8C5YEE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

30608:LRP3
gene id: 30608:LRP3
uniprot id: A0A8B7H359
uniprot id: A0A8B7H561
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:APOA2
gene id: 30608:APOA2
uniprot id: A0A8B7GLY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein A2 family.
messages: Secreted

30608:LOC105864465
gene id: 30608:LOC105864465
uniprot id: A0A8B7FH87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CALCR
gene id: 30608:CALCR
uniprot id: A0A8B7HDT8
uniprot id: A0A8C5VHB0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Interacts with GPRASP2.
messages: Membrane

30608:RARG
gene id: 30608:RARG
uniprot id: A0A8B7G925
uniprot id: A0A8C5V8T3
uniprot id: A0A8C5VGE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

30608:EFTUD2
gene id: 30608:EFTUD2
uniprot id: A0A8B7HVV2
uniprot id: A0A8C5W3F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Nucleus

30608:PLBD2
gene id: 30608:PLBD2
uniprot id: A0A8B7FGX1
uniprot id: A0A8B7FGY1
uniprot id: A0A8B7FI68
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

30608:ERAP1
gene id: 30608:ERAP1
uniprot id: A0A8B7GZS0
uniprot id: A0A8B7GZX7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

30608:PPIE
gene id: 30608:PPIE
uniprot id: A0A8B7HE99
uniprot id: A0A8B7HEM8
uniprot id: A0A8B7HGY0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
messages: Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

30608:ANXA11
gene id: 30608:ANXA11
uniprot id: A0A8C5VDX6
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

30608:MUSTN1
gene id: 30608:MUSTN1
uniprot id: A0A8B7GUC0
uniprot id: A0A8B7GUJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUSTANG family.
messages: Nucleus

30608:UROD
gene id: 30608:UROD
uniprot id: A0A8B7H520
uniprot id: A0A8B7H793
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

30608:LOC105857596
gene id: 30608:LOC105857596
uniprot id: A0A8B7EL24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:EXOSC2
gene id: 30608:EXOSC2
uniprot id: A0A8C5XQQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

30608:TSPAN2
gene id: 30608:TSPAN2
uniprot id: A0A8C5VC23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

30608:MCRIP1
gene id: 30608:MCRIP1
uniprot id: A0A8B7I2G4
uniprot id: A0A8B7I2H1
uniprot id: A0A8B7I4I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

30608:LOC105870134
gene id: 30608:LOC105870134
uniprot id: A0A8B7G6K6
uniprot id: A0A8B7G6L2
uniprot id: A0A8B7G7R4
names: Subcellular Location Annotation
messages: Nucleus

30608:PHF1
gene id: 30608:PHF1
uniprot id: A0A8B7I730
uniprot id: A0A8B7IAC4
uniprot id: A0A8C5VZ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

30608:APOA5
gene id: 30608:APOA5
uniprot id: A0A8B7GZJ3
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

30608:FAM214A
gene id: 30608:FAM214A
uniprot id: A0A8B7G8Y2
uniprot id: A0A8B7GA23
names: Similarity
messages: Belongs to the FAM214 family.

30608:CAMP
gene id: 30608:CAMP
uniprot id: A0A8B7GT92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

30608:LOC105855573
gene id: 30608:LOC105855573
uniprot id: A0A8B7WZ03
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

30608:MANBA
gene id: 30608:MANBA
uniprot id: A0A8B7GT18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Lysosome
messages: Monomer.

30608:ADGRA1
gene id: 30608:ADGRA1
uniprot id: A0A8B7F3D4
names: Subcellular Location Annotation
messages: Membrane

30608:PDF
gene id: 30608:PDF
uniprot id: A0A8B7ERZ3
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins.

30608:TRMO
gene id: 30608:TRMO
uniprot id: A0A8B7GNM2
uniprot id: A0A8B7XB05
uniprot id: A0A8B7XBT9
uniprot id: A0A8C5Y4D6
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

30608:CHAT
gene id: 30608:CHAT
uniprot id: A0A8B7EZ99
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

30608:P3H3
gene id: 30608:P3H3
uniprot id: A0A8B7G1K4
names: Similarity
messages: Belongs to the leprecan family.

30608:PARP4
gene id: 30608:PARP4
uniprot id: A0A8B7XDG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

30608:TNRC6B
gene id: 30608:TNRC6B
uniprot id: A0A8B7EQ00
uniprot id: A0A8B7EQ04
uniprot id: A0A8B7EQ09
uniprot id: A0A8B7ERN6
uniprot id: A0A8B7ERP1
uniprot id: A0A8C5Y8Z1
names: Similarity
messages: Belongs to the GW182 family.

30608:LOC105882888
gene id: 30608:LOC105882888
uniprot id: A0A8B7X908
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C14A family.
messages: Cytoplasm
messages: Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (Caspase-6 subunit p18) and a 11 kDa (Caspase-6 subunit p11) subunit.
messages: Nucleus

30608:MTF2
gene id: 30608:MTF2
uniprot id: A0A8B7I623
uniprot id: A0A8B7I625
uniprot id: A0A8B7WTX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

30608:MUC6
gene id: 30608:MUC6
uniprot id: A0A8B7X5H2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:NXF1
gene id: 30608:NXF1
uniprot id: A0A8C5XPA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm
messages: nucleoplasm

30608:HIGD2A
gene id: 30608:HIGD2A
uniprot id: A0A8C5XW40
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

30608:TMEM55A
gene id: 30608:TMEM55A
uniprot id: A0A8B7G2A3
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: phagosome membrane

30608:LOC105865603
gene id: 30608:LOC105865603
uniprot id: A0A8B7FLV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

30608:ZFYVE26
gene id: 30608:ZFYVE26
uniprot id: A0A8B7HHC8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with AP5Z1, AP5B1, AP5S1 and SPG11. Interacts with TTC19 and KIF13A.
messages: Midbody
messages: Phosphatidylinositol 3-phosphate-binding protein required for the abcission step in cytokinesis: recruited to the midbody during cytokinesis and acts as a regulator of abcission. May also be required for efficient homologous recombination DNA double-strand break repair.

30608:PAXBP1
gene id: 30608:PAXBP1
uniprot id: A0A8B7HGU7
uniprot id: A0A8B7HHI2
names: Similarity
messages: Belongs to the GCF family.

30608:DOCK2
gene id: 30608:DOCK2
uniprot id: A0A8B7WV95
names: Similarity
messages: Belongs to the DOCK family.

30608:EML3
gene id: 30608:EML3
uniprot id: A0A8B7HAE3
uniprot id: A0A8B7HAE4
uniprot id: A0A8B7HAE5
uniprot id: A0A8B7HAE6
uniprot id: A0A8B7HAF1
uniprot id: A0A8B7HD55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EMAP family.
messages: cytoskeleton

30608:LOC105858476
gene id: 30608:LOC105858476
uniprot id: A0A8B7EPX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:DUSP2
gene id: 30608:DUSP2
uniprot id: A0A8C5Y9H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

30608:PLET1
gene id: 30608:PLET1
uniprot id: A0A8B7FA75
names: Function
messages: Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.

30608:CHRNA4
gene id: 30608:CHRNA4
uniprot id: A0A8B7GY62
uniprot id: A0A8C5W1P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:DOCK9
gene id: 30608:DOCK9
uniprot id: A0A8B7FQQ0
uniprot id: A0A8B7FQQ7
uniprot id: A0A8B7FQR4
uniprot id: A0A8B7FQS0
uniprot id: A0A8B7FQS7
uniprot id: A0A8B7FQT2
uniprot id: A0A8B7FQT9
uniprot id: A0A8B7FQV2
uniprot id: A0A8B7FQV7
uniprot id: A0A8B7FQW3
uniprot id: A0A8B7FQW5
uniprot id: A0A8B7FQW8
uniprot id: A0A8B7FQX2
uniprot id: A0A8B7FQX6
uniprot id: A0A8B7FQX7
uniprot id: A0A8B7FQY4
uniprot id: A0A8B7FQY5
uniprot id: A0A8B7FQY9
uniprot id: A0A8B7FQZ1
uniprot id: A0A8B7FQZ7
uniprot id: A0A8B7FR95
uniprot id: A0A8B7FRA3
uniprot id: A0A8B7FRA9
uniprot id: A0A8B7FRB5
uniprot id: A0A8B7FRC3
uniprot id: A0A8B7FRD0
uniprot id: A0A8B7FRU9
uniprot id: A0A8B7FRV5
uniprot id: A0A8B7FRW0
uniprot id: A0A8B7FRW6
uniprot id: A0A8B7FRX7
uniprot id: A0A8B7FRY3
names: Similarity
messages: Belongs to the DOCK family.

30608:LOC105859923
gene id: 30608:LOC105859923
uniprot id: A0A8B7EYG5
uniprot id: A0A8C5VBL0
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

30608:SLC24A5
gene id: 30608:SLC24A5
uniprot id: A0A8C5Y857
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

30608:TAS2R7
gene id: 30608:TAS2R7
uniprot id: A0A8B7EPH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
messages: Membrane

30608:LOC105882802
gene id: 30608:LOC105882802
uniprot id: A0A8C5YEQ3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:GLIPR1
gene id: 30608:GLIPR1
uniprot id: A0A8B7FEW2
uniprot id: A0A8C5V9Z6
names: Similarity
messages: Belongs to the CRISP family.

30608:ZBED4
gene id: 30608:ZBED4
uniprot id: A0A8B7I2U0
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105855010
gene id: 30608:LOC105855010
uniprot id: A0A8B7EA94
uniprot id: A0A8B7ECX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

30608:FAM110A
gene id: 30608:FAM110A
uniprot id: A0A8B7FPB9
names: Similarity
messages: Belongs to the FAM110 family.

30608:KCNAB2
gene id: 30608:KCNAB2
uniprot id: A0A8B7I7L6
uniprot id: A0A8B7I7R7
uniprot id: A0A8B7I9M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: axon
messages: cytoskeleton
messages: synaptosome

30608:GALNT11
gene id: 30608:GALNT11
uniprot id: A0A8B7HUE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

30608:SLC6A3
gene id: 30608:SLC6A3
uniprot id: A0A8B7H0I7
uniprot id: A0A8B7H2J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.
messages: Cell membrane
messages: Membrane
messages: axon
messages: neuron projection

30608:TBCC
gene id: 30608:TBCC
uniprot id: A0A8B7GYG0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCC family.
messages: Cytoplasm
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.

30608:LCN10
gene id: 30608:LCN10
uniprot id: A0A8B7HSA5
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

30608:RMND1
gene id: 30608:RMND1
uniprot id: A0A8C5XDE3
names: Similarity
messages: Belongs to the RMD1/sif2 family.

30608:SERPINB1
gene id: 30608:SERPINB1
uniprot id: A0A8B7GLK8
uniprot id: A0A8B7GLX8
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

30608:TMEM9B
gene id: 30608:TMEM9B
uniprot id: A0A8B7HNX0
uniprot id: A0A8B7HQK2
names: Similarity
messages: Belongs to the TMEM9 family.

30608:ZP3
gene id: 30608:ZP3
uniprot id: A0A8C5V1X0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Membrane
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

30608:DGKD
gene id: 30608:DGKD
uniprot id: A0A8B7I7T1
uniprot id: A0A8B7IB03
uniprot id: A0A8B7X7E3
uniprot id: A0A8B7X930
uniprot id: A0A8C5VJ06
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

30608:TMEM35A
gene id: 30608:TMEM35A
uniprot id: A0A8B7GJM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane
messages: Vesicle

30608:EDEM1
gene id: 30608:EDEM1
uniprot id: A0A8B7G3C0
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

30608:EVL
gene id: 30608:EVL
uniprot id: A0A8B7F4E7
uniprot id: A0A8B7F4E8
uniprot id: A0A8B7F4E9
uniprot id: A0A8B7F4F0
uniprot id: A0A8B7F4F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration.
messages: lamellipodium
messages: stress fiber

30608:FAM83H
gene id: 30608:FAM83H
uniprot id: A0A8B7G0X1
uniprot id: A0A8B7G291
names: Similarity
messages: Belongs to the FAM83 family.

30608:SLC22A5
gene id: 30608:SLC22A5
uniprot id: A0A8C5XBA6
names: Similarity
names: Subunit
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
messages: Interacts with PDZK1.

30608:ADD3
gene id: 30608:ADD3
uniprot id: A0A8B7GSY8
uniprot id: A0A8B7GUK2
uniprot id: A0A8C5XK37
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

30608:LOC105873312
gene id: 30608:LOC105873312
uniprot id: A0A8B7GLD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:VBP1
gene id: 30608:VBP1
uniprot id: A0A8B7FVJ2
uniprot id: A0A8B7FVJ3
uniprot id: A0A8B7FVP9
uniprot id: A0A8B7FWI4
uniprot id: A0A8B7FWI5
uniprot id: A0A8B7FWJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PICALM/SNAP91 family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.
messages: Membrane

30608:LOC105862294
gene id: 30608:LOC105862294
uniprot id: A0A8B7WQR5
names: Subcellular Location Annotation
messages: Nucleus
messages: cell cortex

30608:LIN52
gene id: 30608:LIN52
uniprot id: A0A8B7EQG4
uniprot id: A0A8B7EQN5
uniprot id: A0A8B7EQP6
uniprot id: A0A8B7ES59
uniprot id: A0A8B7ESB3
uniprot id: A0A8B7ESM5
names: Similarity
messages: Belongs to the lin-52 family.

30608:NADK2
gene id: 30608:NADK2
uniprot id: A0A8B7ECM8
uniprot id: A0A8C5VM13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD kinase family.
messages: Homodimer.
messages: Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.
messages: Mitochondrion

30608:C17H16orf91
gene id: 30608:C17H16orf91
uniprot id: A0A8B7EUX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCSMST1 family.
messages: Membrane

30608:UBE2G1
gene id: 30608:UBE2G1
uniprot id: A0A8B7HCT5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:PLP1
gene id: 30608:PLP1
uniprot id: A0A8B7HYN0
uniprot id: A0A8B7HYN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

30608:STIM1
gene id: 30608:STIM1
uniprot id: A0A8B7EY67
uniprot id: A0A8B7EY69
uniprot id: A0A8B7EY70
uniprot id: A0A8B7F011
uniprot id: A0A8C5VIK8
uniprot id: A0A8C5XPT6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:LOC105858368
gene id: 30608:LOC105858368
uniprot id: A0A8B7EPI6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

30608:MYO1D
gene id: 30608:MYO1D
uniprot id: A0A8B7WN97
uniprot id: A0A8B7WNA4
uniprot id: A0A8C5V0N5
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105867136
gene id: 30608:LOC105867136
uniprot id: A0A8B7FTG1
names: Similarity
messages: Belongs to the PPase family.

30608:SDCCAG3
gene id: 30608:SDCCAG3
uniprot id: A0A8B7HJD7
uniprot id: A0A8B7HJD9
uniprot id: A0A8B7HKI2
uniprot id: A0A8B7HLY6
names: Similarity
messages: Belongs to the ENTR1 family.

30608:PKP2
gene id: 30608:PKP2
uniprot id: A0A8C5VC45
names: Similarity
messages: Belongs to the beta-catenin family.

30608:MPP1
gene id: 30608:MPP1
uniprot id: A0A8B7ERL1
names: Function
names: Subcellular Location Annotation
messages: Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity.
messages: stereocilium

30608:LOC105883389
gene id: 30608:LOC105883389
uniprot id: A0A8B7HX42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:KRR1
gene id: 30608:KRR1
uniprot id: A0A8B7FDY6
uniprot id: A0A8B7FEV7
uniprot id: A0A8B7X707
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

30608:FGF17
gene id: 30608:FGF17
uniprot id: A0A8B7EJ53
uniprot id: A0A8B7EJ59
uniprot id: A0A8B7EK97
uniprot id: A0A8B7EKA2
uniprot id: A0A8C6EK78
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

30608:AVL9
gene id: 30608:AVL9
uniprot id: A0A8B7ER75
uniprot id: A0A8C5W330
names: Subcellular Location Annotation
messages: Endosome
messages: Recycling endosome

30608:LOC105879533
gene id: 30608:LOC105879533
uniprot id: A0A8C5Y4C7
names: Similarity
messages: Belongs to the TGF-beta family.

30608:LOC105861269
gene id: 30608:LOC105861269
uniprot id: A0A8B7X565
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:BET1
gene id: 30608:BET1
uniprot id: A0A8B7FTX6
names: Subcellular Location Annotation
messages: Membrane

30608:SLCO2A1
gene id: 30608:SLCO2A1
uniprot id: A0A8C5YI85
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:PPP3R1
gene id: 30608:PPP3R1
uniprot id: A0A8B7FBQ4
uniprot id: A0A8B7FBV8
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

30608:TMEM131
gene id: 30608:TMEM131
uniprot id: A0A8B7HWB2
uniprot id: A0A8B7HWC3
uniprot id: A0A8B7HYE7
names: Similarity
messages: Belongs to the TMEM131 family.

30608:SUDS3
gene id: 30608:SUDS3
uniprot id: A0A8B7FSM4
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105884611
gene id: 30608:LOC105884611
uniprot id: A0A8B7I0P2
uniprot id: A0A8B7I0P3
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

30608:CLDN34
gene id: 30608:CLDN34
uniprot id: A0A8B7WZA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

30608:SLC35D1
gene id: 30608:SLC35D1
uniprot id: A0A8C5VJB4
names: Subcellular Location Annotation
messages: Membrane

30608:CPPED1
gene id: 30608:CPPED1
uniprot id: A0A8B7WNL9
uniprot id: A0A8B7WNR1
names: Function
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. CPPED1 family.
messages: Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.

30608:LOC105875331
gene id: 30608:LOC105875331
uniprot id: A0A8B7GXV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:KCNJ5
gene id: 30608:KCNJ5
uniprot id: A0A8B7GW41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.
messages: Membrane

30608:PEBP1
gene id: 30608:PEBP1
uniprot id: A0A8B7FSA7
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

30608:CRYBA4
gene id: 30608:CRYBA4
uniprot id: A0A8B7GA27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

30608:SLBP
gene id: 30608:SLBP
uniprot id: A0A8B7HMD9
uniprot id: A0A8B7HME1
uniprot id: A0A8B7HME6
uniprot id: A0A8B7HNV4
uniprot id: A0A8B7HPV3
uniprot id: A0A8B7HPV8
uniprot id: A0A8C5Y1I8
uniprot id: A0A8C5Y3C0
names: Similarity
messages: Belongs to the FAM53 family.
messages: Belongs to the SLBP family.

30608:LOC105868502
gene id: 30608:LOC105868502
uniprot id: A0A8B7FZI3
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:LPIN3
gene id: 30608:LPIN3
uniprot id: A0A8B7HHI9
uniprot id: A0A8B7HHL5
names: Similarity
messages: Belongs to the lipin family.

30608:LOC105884308
gene id: 30608:LOC105884308
uniprot id: A0A8B7HZ23
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

30608:CCDC126
gene id: 30608:CCDC126
uniprot id: A0A8B7GYS4
names: Subcellular Location Annotation
messages: Secreted

30608:PLD4
gene id: 30608:PLD4
uniprot id: A0A8B7F3X4
uniprot id: A0A8B7X0L0
uniprot id: A0A8B7X1R5
names: Similarity
messages: Belongs to the phospholipase D family.

30608:PTTG1
gene id: 30608:PTTG1
uniprot id: A0A8B7HUN9
uniprot id: A0A8C5US66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

30608:ANAPC1
gene id: 30608:ANAPC1
uniprot id: A0A8B7EUQ9
uniprot id: A0A8B7EUW7
names: Similarity
messages: Belongs to the APC1 family.

30608:SPP2
gene id: 30608:SPP2
uniprot id: A0A8B7FJM2
uniprot id: A0A8B7FKY2
uniprot id: A0A8B7FKY7
uniprot id: A0A8C5XYF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Could coordinate an aspect of bone turnover.
messages: Secreted

30608:FNTA
gene id: 30608:FNTA
uniprot id: A0A8C5V9J1
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

30608:GLUL
gene id: 30608:GLUL
uniprot id: A0A8B7EA96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cell membrane
messages: Membrane
messages: Microsome

30608:MED10
gene id: 30608:MED10
uniprot id: A0A8B7EYG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

30608:JAG2
gene id: 30608:JAG2
uniprot id: A0A8B7F3M6
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

30608:RFLNB
gene id: 30608:RFLNB
uniprot id: A0A8B7EN68
uniprot id: A0A8C5XGA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

30608:NDUFA11
gene id: 30608:NDUFA11
uniprot id: A0A8B7G5X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA11 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

30608:MCUR1
gene id: 30608:MCUR1
uniprot id: A0A8B7FJW1
names: Similarity
messages: Belongs to the CCDC90 family.

30608:COQ6
gene id: 30608:COQ6
uniprot id: A0A8C5VUN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Cell projection
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ7.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Golgi apparatus
messages: Mitochondrion inner membrane

30608:CENPA
gene id: 30608:CENPA
uniprot id: A0A8B7X8V9
names: Similarity
messages: Belongs to the histone H3 family.

30608:DFNA5
gene id: 30608:DFNA5
uniprot id: A0A8B7GYM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

30608:RSPO1
gene id: 30608:RSPO1
uniprot id: A0A8C5VPX4
names: Similarity
messages: Belongs to the R-spondin family.

30608:C3
gene id: 30608:C3
uniprot id: A0A8B7WVJ2
uniprot id: A0A8B7WVU7
uniprot id: A0A8B7WW58
names: Function
names: Subcellular Location Annotation
messages: Acts as a chemoattractant for neutrophils in chronic inflammation.
messages: C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
messages: Secreted

30608:MRPL11
gene id: 30608:MRPL11
uniprot id: A0A8B7FVE2
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

30608:NCBP3
gene id: 30608:NCBP3
uniprot id: A0A8B7WNE2
names: Similarity
messages: Belongs to the NCBP3 family.

30608:FAM221A
gene id: 30608:FAM221A
uniprot id: A0A8B7GYM2
uniprot id: A0A8B7GYP1
uniprot id: A0A8C5Y2B6
names: Similarity
messages: Belongs to the FAM221 family.

30608:ASPM
gene id: 30608:ASPM
uniprot id: A0A8B7EWU2
uniprot id: A0A8B7EYR1
uniprot id: A0A8B7EYU8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:MEGF9
gene id: 30608:MEGF9
uniprot id: A0A8B7GUK1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:INTS9
gene id: 30608:INTS9
uniprot id: A0A8B7H3P7
uniprot id: A0A8B7H3Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

30608:POLR3B
gene id: 30608:POLR3B
uniprot id: A0A8B7GXB7
uniprot id: A0A8B7GXC2
uniprot id: A0A8B7GZ63
uniprot id: A0A8C5XMD2
uniprot id: A0A8C6EHW6
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

30608:LOC105859029
gene id: 30608:LOC105859029
uniprot id: A0A8B7ESB7
uniprot id: A0A8B7ESC3
uniprot id: A0A8B7EU50
names: Subcellular Location Annotation
messages: Membrane

30608:TMEFF2
gene id: 30608:TMEFF2
uniprot id: A0A8B7H9S4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:RAB11FIP3
gene id: 30608:RAB11FIP3
uniprot id: A0A8B7EI10
uniprot id: A0A8C5XS40
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: Endosome membrane
messages: Membrane
messages: Midbody
messages: Recycling endosome membrane

30608:STON1
gene id: 30608:STON1
uniprot id: A0A8B7FPP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Cytoplasm
messages: May be involved in the endocytic machinery.

30608:PRAF2
gene id: 30608:PRAF2
uniprot id: A0A8C5XUM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

30608:LOC105868732
gene id: 30608:LOC105868732
uniprot id: A0A8B7G055
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PLCD1
gene id: 30608:PLCD1
uniprot id: A0A8B7FS11
uniprot id: A0A8B7FS50
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

30608:NPTX2
gene id: 30608:NPTX2
uniprot id: A0A8C5VP79
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SLIT2
gene id: 30608:SLIT2
uniprot id: A0A8B7EEM8
uniprot id: A0A8B7EEN5
uniprot id: A0A8B7EFC8
uniprot id: A0A8C5XQ55
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:LOC105881622
gene id: 30608:LOC105881622
uniprot id: A0A8B7HNR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105859566
gene id: 30608:LOC105859566
uniprot id: A0A8B7EUH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105883762
gene id: 30608:LOC105883762
uniprot id: A0A8B7HWW6
names: Similarity
messages: Belongs to the histone H2B family.

30608:AGPAT3
gene id: 30608:AGPAT3
uniprot id: A0A8C5Y213
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Endoplasmic reticulum membrane

30608:ZDHHC12
gene id: 30608:ZDHHC12
uniprot id: A0A8B7GVT7
uniprot id: A0A8C5V5M5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

30608:ABT1
gene id: 30608:ABT1
uniprot id: A0A8B7ER38
uniprot id: A0A8C5Y3I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

30608:PGP
gene id: 30608:PGP
uniprot id: A0A8B7EWY2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

30608:LOC105859845
gene id: 30608:LOC105859845
uniprot id: A0A8B7EW18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I) and RNA polymerase III (Pol III) complexes consisting of at least 13 and 17 subunits, respectively.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.

30608:PTGES3L
gene id: 30608:PTGES3L
uniprot id: A0A8B7EU07
names: Similarity
messages: Belongs to the p23/wos2 family.

30608:ZFP36
gene id: 30608:ZFP36
uniprot id: A0A8C5W739
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

30608:BPIFC
gene id: 30608:BPIFC
uniprot id: A0A8B7X8Q4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

30608:LOC105872744
gene id: 30608:LOC105872744
uniprot id: A0A8C6ELM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SRRD
gene id: 30608:SRRD
uniprot id: A0A8B7GAC5
names: Similarity
messages: Belongs to the SRR1 family.

30608:CORO2B
gene id: 30608:CORO2B
uniprot id: A0A8B7GLB7
uniprot id: A0A8B7GLC7
uniprot id: A0A8B7GLN6
uniprot id: A0A8B7GLY0
names: Similarity
messages: Belongs to the WD repeat coronin family.

30608:LOC105869356
gene id: 30608:LOC105869356
uniprot id: A0A8B7G348
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:CHST8
gene id: 30608:CHST8
uniprot id: A0A8B7H551
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:NDUFAF7
gene id: 30608:NDUFAF7
uniprot id: A0A8B7I028
uniprot id: A0A8B7I036
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

30608:LOC105883370
gene id: 30608:LOC105883370
uniprot id: A0A8B7HUW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:EBP
gene id: 30608:EBP
uniprot id: A0A8C5VPZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:DMRTC2
gene id: 30608:DMRTC2
uniprot id: A0A8B7WVS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

30608:SPECC1
gene id: 30608:SPECC1
uniprot id: A0A8B7EFQ2
uniprot id: A0A8B7EFQ5
uniprot id: A0A8B7EFQ7
uniprot id: A0A8B7EG88
uniprot id: A0A8B7EGK3
uniprot id: A0A8B7EI86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

30608:PFDN4
gene id: 30608:PFDN4
uniprot id: A0A8B7G3E7
uniprot id: A0A8B7G4T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

30608:ENDOG
gene id: 30608:ENDOG
uniprot id: A0A8C5V6G6
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

30608:LOC105861294
gene id: 30608:LOC105861294
uniprot id: A0A8B7F445
names: Subcellular Location Annotation
messages: Membrane

30608:PRKCZ
gene id: 30608:PRKCZ
uniprot id: A0A8B7WNI6
uniprot id: A0A8B7WNJ4
uniprot id: A0A8B7WNJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

30608:LOC105880282
gene id: 30608:LOC105880282
uniprot id: A0A8B7X0Q5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:IMPA2
gene id: 30608:IMPA2
uniprot id: A0A8B7F1K8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

30608:SEC13
gene id: 30608:SEC13
uniprot id: A0A8B7G222
uniprot id: A0A8B7G223
uniprot id: A0A8B7G226
uniprot id: A0A8B7G228
uniprot id: A0A8B7G3H0
uniprot id: A0A8C5UNN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane
messages: nuclear pore complex

30608:ITPK1
gene id: 30608:ITPK1
uniprot id: A0A8B7EHG0
uniprot id: A0A8B7EHG6
uniprot id: A0A8B7EIF7
uniprot id: A0A8B7X0H1
uniprot id: A0A8B7X112
uniprot id: A0A8C5UK98
names: Similarity
messages: Belongs to the ITPK1 family.

30608:LOC105884122
gene id: 30608:LOC105884122
uniprot id: A0A8B7X4K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TRIAP1
gene id: 30608:TRIAP1
uniprot id: A0A8B7FSL2
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

30608:PSMD13
gene id: 30608:PSMD13
uniprot id: A0A8B7GPR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S11 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

30608:DPY19L4
gene id: 30608:DPY19L4
uniprot id: A0A8B7GXL6
uniprot id: A0A8C5VBI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

30608:OCSTAMP
gene id: 30608:OCSTAMP
uniprot id: A0A8B7EUZ6
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105875133
gene id: 30608:LOC105875133
uniprot id: A0A8B7GUR9
uniprot id: A0A8B7GUS0
uniprot id: A0A8B7GUV3
uniprot id: A0A8B7GWJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

30608:KCNJ1
gene id: 30608:KCNJ1
uniprot id: A0A8B7GW39
uniprot id: A0A8B7GW77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

30608:CAMK2D
gene id: 30608:CAMK2D
uniprot id: A0A8B7HE46
uniprot id: A0A8B7HE50
uniprot id: A0A8B7HE65
uniprot id: A0A8B7HE71
uniprot id: A0A8B7HEG7
uniprot id: A0A8B7HEH5
uniprot id: A0A8B7HGS1
uniprot id: A0A8B7HGS5
uniprot id: A0A8B7WXU0
uniprot id: A0A8B7WY80
uniprot id: A0A8C5Y0M1
uniprot id: A0A8C5Y2H2
uniprot id: A0A8C5YCE3
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

30608:GSG1L
gene id: 30608:GSG1L
uniprot id: A0A8B7FY95
uniprot id: A0A8B7WPD4
uniprot id: A0A8C5Y2W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

30608:UPK1A
gene id: 30608:UPK1A
uniprot id: A0A8B7H2N5
uniprot id: A0A8B7H2V2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:TRAF4
gene id: 30608:TRAF4
uniprot id: A0A8B7EMF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

30608:VPS4B
gene id: 30608:VPS4B
uniprot id: A0A8C5VNJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Late endosome membrane

30608:NLE1
gene id: 30608:NLE1
uniprot id: A0A8B7I3Z7
names: Subcellular Location Annotation
messages: nucleolus

30608:IL12A
gene id: 30608:IL12A
uniprot id: A0A8B7HKZ2
uniprot id: A0A8C6ELQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity. Mechanistically, exerts its biological effects through a receptor composed of IL12R1 and IL12R2 subunits. Binding to the receptor results in the rapid tyrosine phosphorylation of a number of cellular substrates including the JAK family kinases TYK2 and JAK2. In turn, recruited STAT4 gets phosphorylated and translocates to the nucleus where it regulates cytokine/growth factor responsive genes. As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and functions also as an immune-suppressive cytokine. Mediates biological events through unconventional receptors composed of IL12RB2 and gp130/IL6ST heterodimers or homodimers. Signaling requires the transcription factors STAT1 and STAT4, which form a unique heterodimer that binds to distinct DNA sites.
messages: Secreted

30608:STAMBPL1
gene id: 30608:STAMBPL1
uniprot id: A0A8B7GDI1
uniprot id: A0A8B7GDL0
names: Similarity
messages: Belongs to the peptidase M67C family.

30608:TRMU
gene id: 30608:TRMU
uniprot id: A0A8B7FTF2
uniprot id: A0A8B7FTK9
uniprot id: A0A8B7FTL4
uniprot id: A0A8B7FTM3
uniprot id: A0A8C5Y547
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

30608:CCNB3
gene id: 30608:CCNB3
uniprot id: A0A8B7FTE2
uniprot id: A0A8B7FTE8
uniprot id: A0A8B7FU56
names: Similarity
messages: Belongs to the cyclin family.

30608:DNASE2B
gene id: 30608:DNASE2B
uniprot id: A0A8B7F5M7
uniprot id: A0A8B7F5P2
uniprot id: A0A8C5VCJ3
names: Similarity
messages: Belongs to the DNase II family.

30608:NONO
gene id: 30608:NONO
uniprot id: A0A8B7EBH8
names: Subcellular Location Annotation
messages: Nucleus speckle

30608:LOC105880095
gene id: 30608:LOC105880095
uniprot id: A0A8C5WBM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

30608:NDEL1
gene id: 30608:NDEL1
uniprot id: A0A8B7H371
uniprot id: A0A8B7H382
uniprot id: A0A8B7H3D8
uniprot id: A0A8C5XZJ9
uniprot id: A0A8C5Y0P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: kinetochore
messages: spindle

30608:MRPL12
gene id: 30608:MRPL12
uniprot id: A0A8C5XYV0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

30608:BAG6
gene id: 30608:BAG6
uniprot id: A0A8B7ENE8
uniprot id: A0A8B7ENF2
uniprot id: A0A8B7ENF6
uniprot id: A0A8B7ENG1
uniprot id: A0A8B7ENH4
uniprot id: A0A8B7ENK5
uniprot id: A0A8B7ENL1
uniprot id: A0A8B7ENL6
uniprot id: A0A8B7EPY6
uniprot id: A0A8B7EPZ1
uniprot id: A0A8B7EPZ6
uniprot id: A0A8B7EQ01
uniprot id: A0A8B7EQK9
uniprot id: A0A8B7EQL2
uniprot id: A0A8B7EQL8
uniprot id: A0A8B7EQM2
uniprot id: A0A8C5W4V8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Released extracellularly via exosomes, it is a ligand of the natural killer/NK cells receptor NCR3 and stimulates NK cells cytotoxicity. It may thereby trigger NK cells cytotoxicity against neighboring tumor cells and immature myeloid dendritic cells (DC).
messages: extracellular exosome

30608:LIPH
gene id: 30608:LIPH
uniprot id: A0A8C5YHW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

30608:PAX1
gene id: 30608:PAX1
uniprot id: A0A8B7EJD4
names: Subcellular Location Annotation
messages: Nucleus

30608:FSHB
gene id: 30608:FSHB
uniprot id: A0A8C5UYE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

30608:RASGRP3
gene id: 30608:RASGRP3
uniprot id: A0A8B7I002
uniprot id: A0A8B7I007
names: Similarity
messages: Belongs to the RASGRP family.

30608:PKIB
gene id: 30608:PKIB
uniprot id: A0A8B7H8M2
uniprot id: A0A8B7H8N4
uniprot id: A0A8B7X4W6
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

30608:MUC17
gene id: 30608:MUC17
uniprot id: A0A8B7WPL3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PARP16
gene id: 30608:PARP16
uniprot id: A0A8B7FXL7
uniprot id: A0A8B7FYK0
uniprot id: A0A8B7FYP2
uniprot id: A0A8C5UUG5
uniprot id: A0A8C5VG91
names: Similarity
messages: Belongs to the ARTD/PARP family.

30608:GCK
gene id: 30608:GCK
uniprot id: A0A8B7ERA0
uniprot id: A0A8C5VXM3
names: Similarity
messages: Belongs to the hexokinase family.

30608:PROM2
gene id: 30608:PROM2
uniprot id: A0A8B7HW30
uniprot id: A0A8B7X2U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

30608:STK40
gene id: 30608:STK40
uniprot id: A0A8C5XCN8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
messages: Nucleus

30608:RAB4A
gene id: 30608:RAB4A
uniprot id: A0A8C5XMQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

30608:SUGP2
gene id: 30608:SUGP2
uniprot id: A0A8B7EPF2
uniprot id: A0A8B7EPJ4
uniprot id: A0A8B7ERL2
names: Subcellular Location Annotation
messages: Nucleus

30608:GPR135
gene id: 30608:GPR135
uniprot id: A0A8B7HV83
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:HADHA
gene id: 30608:HADHA
uniprot id: A0A8B7HZA6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

30608:RDH5
gene id: 30608:RDH5
uniprot id: A0A8B7FIM0
uniprot id: A0A8B7X5X5
uniprot id: A0A8C5YCU5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:LMOD1
gene id: 30608:LMOD1
uniprot id: A0A8B7EWY4
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

30608:NDP
gene id: 30608:NDP
uniprot id: A0A8B7FLK5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:REEP6
gene id: 30608:REEP6
uniprot id: A0A8B7F0H4
uniprot id: A0A8B7WWB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

30608:ITGB8
gene id: 30608:ITGB8
uniprot id: A0A8B7HH42
uniprot id: A0A8B7XE24
uniprot id: A0A8C5XVZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

30608:MOB3C
gene id: 30608:MOB3C
uniprot id: A0A8B7H557
uniprot id: A0A8B7H559
uniprot id: A0A8B7H562
uniprot id: A0A8B7H564
uniprot id: A0A8B7H7G8
uniprot id: A0A8B7XBM9
uniprot id: A0A8C5VQZ1
names: Similarity
messages: Belongs to the MOB1/phocein family.
messages: Belongs to the protein kinase superfamily.

30608:KIFC3
gene id: 30608:KIFC3
uniprot id: A0A8B7EVS8
uniprot id: A0A8B7EVS9
uniprot id: A0A8B7EVT2
uniprot id: A0A8B7EVU0
uniprot id: A0A8B7EXR3
uniprot id: A0A8B7EXR8
uniprot id: A0A8B7EXS8
uniprot id: A0A8B7WRW9
uniprot id: A0A8C5W169
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:XRCC3
gene id: 30608:XRCC3
uniprot id: A0A8B7F3S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Cytoplasm
messages: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions.
messages: Nucleus

30608:PPIP5K2
gene id: 30608:PPIP5K2
uniprot id: A0A8B7GYE0
uniprot id: A0A8B7XD40
uniprot id: A0A8B7XD41
uniprot id: A0A8B7XD46
uniprot id: A0A8B7XD48
uniprot id: A0A8B7XD49
uniprot id: A0A8B7XD53
uniprot id: A0A8B7XD54
uniprot id: A0A8B7XD58
uniprot id: A0A8B7XEB9
uniprot id: A0A8B7XEC5
uniprot id: A0A8B7XED1
uniprot id: A0A8B7XEE0
uniprot id: A0A8B7XET3
uniprot id: A0A8B7XET8
uniprot id: A0A8B7XEU3
uniprot id: A0A8B7XEU7
uniprot id: A0A8B7XEV2
uniprot id: A0A8B7XFC4
uniprot id: A0A8B7XFD3
uniprot id: A0A8B7XFD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

30608:IMP3
gene id: 30608:IMP3
uniprot id: A0A8B7X1V0
uniprot id: A0A8B7X3L2
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

30608:MGST2
gene id: 30608:MGST2
uniprot id: A0A8B7GGY9
uniprot id: A0A8C5Y6X5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

30608:SLC5A11
gene id: 30608:SLC5A11
uniprot id: A0A8B7HEZ0
uniprot id: A0A8B7HFF6
uniprot id: A0A8B7WNX0
uniprot id: A0A8B7WNY2
uniprot id: A0A8B7WP11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

30608:SNAP23
gene id: 30608:SNAP23
uniprot id: A0A8B7GGU2
uniprot id: A0A8B7GHJ0
uniprot id: A0A8B7GHP7
uniprot id: A0A8B7GHQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

30608:PPP1R16B
gene id: 30608:PPP1R16B
uniprot id: A0A8C5XRP7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:TRAPPC5
gene id: 30608:TRAPPC5
uniprot id: A0A8B7I5N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: cis-Golgi network

30608:UFL1
gene id: 30608:UFL1
uniprot id: A0A8C5XD19
names: Similarity
messages: Belongs to the UFL1 family.

30608:TSPAN3
gene id: 30608:TSPAN3
uniprot id: A0A8B7HPC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

30608:LOC105872034
gene id: 30608:LOC105872034
uniprot id: A0A8B7GEU3
uniprot id: A0A8B7GEU9
names: Similarity
messages: Belongs to the intermediate filament family.

30608:USP4
gene id: 30608:USP4
uniprot id: A0A8B7GTJ7
uniprot id: A0A8B7GTR0
uniprot id: A0A8C5XTR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Nucleus

30608:LOC105879638
gene id: 30608:LOC105879638
uniprot id: A0A8B7HHA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with RRN3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm

30608:WNT5A
gene id: 30608:WNT5A
uniprot id: A0A8B7FIT9
uniprot id: A0A8B7FIX2
uniprot id: A0A8B7FJ13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

30608:OSBPL1A
gene id: 30608:OSBPL1A
uniprot id: A0A8B7F0U4
uniprot id: A0A8B7F0U6
uniprot id: A0A8B7F0U7
uniprot id: A0A8B7F0U9
uniprot id: A0A8B7F0V2
uniprot id: A0A8B7F2L4
uniprot id: A0A8C5XEE8
names: Similarity
messages: Belongs to the OSBP family.

30608:LOC105864634
gene id: 30608:LOC105864634
uniprot id: A0A8B7FHV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ARHGEF1
gene id: 30608:ARHGEF1
uniprot id: A0A8B7FX28
uniprot id: A0A8B7FXU6
uniprot id: A0A8B7FXX5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

30608:SOX2
gene id: 30608:SOX2
uniprot id: A0A8C5YIX8
names: Subcellular Location Annotation
messages: Nucleus

30608:NUDT6
gene id: 30608:NUDT6
uniprot id: A0A8B7WKM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Cytoplasm
messages: May contribute to the regulation of cell proliferation.
messages: Mitochondrion
messages: Monomer and homodimer.
messages: Nucleus

30608:LHFPL2
gene id: 30608:LHFPL2
uniprot id: A0A8B7GHS1
names: Subcellular Location Annotation
messages: Membrane

30608:KIF6
gene id: 30608:KIF6
uniprot id: A0A8B7HAM6
uniprot id: A0A8C6EJ77
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:JAK2
gene id: 30608:JAK2
uniprot id: A0A8B7EI24
uniprot id: A0A8B7XBH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Cytoplasm
messages: Endomembrane system
messages: Nucleus

30608:AGRP
gene id: 30608:AGRP
uniprot id: A0A8C6EFV5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:RASGRP4
gene id: 30608:RASGRP4
uniprot id: A0A8B7H408
uniprot id: A0A8B7WU08
uniprot id: A0A8B7WU58
uniprot id: A0A8B7WVE9
names: Similarity
messages: Belongs to the RASGRP family.

30608:KCNK10
gene id: 30608:KCNK10
uniprot id: A0A8B7H0G5
uniprot id: A0A8B7X0D9
uniprot id: A0A8C5VB16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

30608:BIRC7
gene id: 30608:BIRC7
uniprot id: A0A8B7GXP8
names: Similarity
messages: Belongs to the IAP family.

30608:KIF1A
gene id: 30608:KIF1A
uniprot id: A0A8B7X7W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: axon

30608:GPR37
gene id: 30608:GPR37
uniprot id: A0A8B7I4H5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:PTEN
gene id: 30608:PTEN
uniprot id: A0A8B7G7P5
uniprot id: A0A8B7G8D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.
messages: Belongs to the PTEN phosphatase protein family.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Postsynaptic density
messages: dendritic spine

30608:HIP1R
gene id: 30608:HIP1R
uniprot id: A0A8B7HJS8
uniprot id: A0A8B7HJT1
uniprot id: A0A8B7HJT2
uniprot id: A0A8B7HJT3
uniprot id: A0A8B7HKY1
uniprot id: A0A8B7HMB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLA2 family.
messages: Membrane

30608:RAF1
gene id: 30608:RAF1
uniprot id: A0A8B7HU38
uniprot id: A0A8C5XJ93
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

30608:LOC105867252
gene id: 30608:LOC105867252
uniprot id: A0A8B7FTN6
names: Similarity
messages: Belongs to the complex I LYR family. LYRM9 subfamily.

30608:XIRP1
gene id: 30608:XIRP1
uniprot id: A0A8B7WZX6
names: Domain
names: Function
names: Similarity
messages: Belongs to the Xin family.
messages: Protects actin filaments from depolymerization.
messages: Xin repeats bind F-actin.

30608:LOC105866820
gene id: 30608:LOC105866820
uniprot id: A0A8B7FSR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NLRP family.
messages: Inflammasome
messages: cytosol

30608:LOC105876665
gene id: 30608:LOC105876665
uniprot id: A0A8B7WV20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

30608:SLC2A5
gene id: 30608:SLC2A5
uniprot id: A0A8B7I7D5
uniprot id: A0A8B7I7J4
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane
messages: sarcolemma

30608:LOC105884082
gene id: 30608:LOC105884082
uniprot id: A0A8B7I0H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105866514
gene id: 30608:LOC105866514
uniprot id: A0A8B7FQV8
names: Subcellular Location Annotation
messages: Membrane

30608:PSCA
gene id: 30608:PSCA
uniprot id: A0A8B7HKM8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:PTGES2
gene id: 30608:PTGES2
uniprot id: A0A8B7GVQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily.
messages: Membrane

30608:MAP4K1
gene id: 30608:MAP4K1
uniprot id: A0A8B7H1Y0
uniprot id: A0A8B7H234
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

30608:VCP
gene id: 30608:VCP
uniprot id: A0A8C5UXW8
names: Similarity
messages: Belongs to the AAA ATPase family.

30608:EREG
gene id: 30608:EREG
uniprot id: A0A8B7EYY7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:JRK
gene id: 30608:JRK
uniprot id: A0A8B7HLV4
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC109730535
gene id: 30608:LOC109730535
uniprot id: A0A8B7X1Z2
names: Subcellular Location Annotation
messages: Membrane

30608:FARSA
gene id: 30608:FARSA
uniprot id: A0A8B7I7Z9
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

30608:ITGA4
gene id: 30608:ITGA4
uniprot id: A0A8B7HVJ3
uniprot id: A0A8C5V037
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

30608:IRAK1BP1
gene id: 30608:IRAK1BP1
uniprot id: A0A8C5Y4Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

30608:LOC105874058
gene id: 30608:LOC105874058
uniprot id: A0A8B7X5J3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ATP10B
gene id: 30608:ATP10B
uniprot id: A0A8B7HUM9
uniprot id: A0A8B7HWV4
uniprot id: A0A8C5XFV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

30608:RNASE6
gene id: 30608:RNASE6
uniprot id: A0A8B7FHU9
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

30608:ATP2A2
gene id: 30608:ATP2A2
uniprot id: A0A8B7HK04
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

30608:RIMKLA
gene id: 30608:RIMKLA
uniprot id: A0A8B7F7T4
names: Similarity
messages: Belongs to the RimK family.

30608:TARSL2
gene id: 30608:TARSL2
uniprot id: A0A8B7GCV3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

30608:EGFR
gene id: 30608:EGFR
uniprot id: A0A8B7H412
uniprot id: A0A8B7H415
uniprot id: A0A8B7H454
uniprot id: A0A8B7H697
uniprot id: A0A8B7XE99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

30608:SUMO2
gene id: 30608:SUMO2
uniprot id: A0A8B7HBQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

30608:NME3
gene id: 30608:NME3
uniprot id: A0A8B7EUW3
uniprot id: A0A8C6EEJ3
names: Similarity
messages: Belongs to the NDK family.

30608:SH3BGRL2
gene id: 30608:SH3BGRL2
uniprot id: A0A8B7GNB6
names: Similarity
messages: Belongs to the SH3BGR family.

30608:LGSN
gene id: 30608:LGSN
uniprot id: A0A8C5VU20
names: Similarity
messages: Belongs to the glutamine synthetase family.

30608:PGC
gene id: 30608:PGC
uniprot id: A0A8B7H0G1
names: Function
names: Similarity
messages: Belongs to the peptidase A1 family.
messages: Hydrolyzes a variety of proteins.

30608:VGLL2
gene id: 30608:VGLL2
uniprot id: A0A8B7FL11
uniprot id: A0A8B7FM86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

30608:LOC109730386
gene id: 30608:LOC109730386
uniprot id: A0A8B7X085
names: Similarity
messages: Belongs to the histone H3 family.

30608:COQ8A
gene id: 30608:COQ8A
uniprot id: A0A8C5V1H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Membrane
messages: Mitochondrion

30608:UNC93A
gene id: 30608:UNC93A
uniprot id: A0A8B7H702
uniprot id: A0A8B7H704
uniprot id: A0A8B7H722
uniprot id: A0A8B7X579
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

30608:ATG13
gene id: 30608:ATG13
uniprot id: A0A8B7I352
uniprot id: A0A8B7I368
uniprot id: A0A8B7I383
uniprot id: A0A8B7I395
uniprot id: A0A8B7I3B5
uniprot id: A0A8B7I538
uniprot id: A0A8B7I547
uniprot id: A0A8B7I608
uniprot id: A0A8B7I660
uniprot id: A0A8B7I665
uniprot id: A0A8B7X2Z0
uniprot id: A0A8B7X4Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
messages: Belongs to the ATG13 family. Metazoan subfamily.
messages: Preautophagosomal structure

30608:CEP55
gene id: 30608:CEP55
uniprot id: A0A8B7GGF1
names: Subcellular Location Annotation
messages: Cytoplasm

30608:VGLL1
gene id: 30608:VGLL1
uniprot id: A0A8B7FRZ1
uniprot id: A0A8B7FS31
uniprot id: A0A8B7FSL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

30608:C7H12orf10
gene id: 30608:C7H12orf10
uniprot id: A0A8C5V259
names: Similarity
messages: Belongs to the MYG1 family.

30608:CRYBA2
gene id: 30608:CRYBA2
uniprot id: A0A8C5Y4F9
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

30608:KRT72
gene id: 30608:KRT72
uniprot id: A0A8C5UM81
uniprot id: A0A8C5VLS8
names: Similarity
messages: Belongs to the intermediate filament family.

30608:PRDM7
gene id: 30608:PRDM7
uniprot id: A0A8B7EDY8
names: Subcellular Location Annotation
messages: Nucleus

30608:FSCN3
gene id: 30608:FSCN3
uniprot id: A0A8B7I1N9
uniprot id: A0A8B7I4J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

30608:CPT1A
gene id: 30608:CPT1A
uniprot id: A0A8C5US47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

30608:SH2B3
gene id: 30608:SH2B3
uniprot id: A0A8B7HAU4
uniprot id: A0A8B7HDK0
names: Similarity
messages: Belongs to the SH2B adapter family.

30608:CHMP1B
gene id: 30608:CHMP1B
uniprot id: A0A8B7F3J8
names: Similarity
messages: Belongs to the SNF7 family.

30608:DNM2
gene id: 30608:DNM2
uniprot id: A0A8B7I598
uniprot id: A0A8B7I5A3
uniprot id: A0A8B7I5A5
uniprot id: A0A8B7I5A8
uniprot id: A0A8B7I5C8
uniprot id: A0A8B7I5D3
uniprot id: A0A8B7I5D8
uniprot id: A0A8B7I7A7
uniprot id: A0A8B7I8G0
uniprot id: A0A8B7I8G5
uniprot id: A0A8B7WWR9
uniprot id: A0A8C5VMV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: cytoskeleton

30608:RUNX1
gene id: 30608:RUNX1
uniprot id: A0A8B7HLE3
uniprot id: A0A8B7HMQ2
names: Function
names: Subcellular Location Annotation
messages: Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
messages: Nucleus

30608:SKA1
gene id: 30608:SKA1
uniprot id: A0A8B7GQ39
names: Similarity
messages: Belongs to the SKA1 family.

30608:SMPD2
gene id: 30608:SMPD2
uniprot id: A0A8B7FJC8
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

30608:EIF2S2
gene id: 30608:EIF2S2
uniprot id: A0A8B7FMU3
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

30608:UBE4A
gene id: 30608:UBE4A
uniprot id: A0A8B7X437
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

30608:MRI1
gene id: 30608:MRI1
uniprot id: A0A8B7WW22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

30608:POU6F1
gene id: 30608:POU6F1
uniprot id: A0A8B7G6L5
uniprot id: A0A8B7G769
uniprot id: A0A8B7G774
uniprot id: A0A8B7G793
uniprot id: A0A8B7X7D6
uniprot id: A0A8C5W3V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

30608:IRX3
gene id: 30608:IRX3
uniprot id: A0A8B7GWY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

30608:SLC12A6
gene id: 30608:SLC12A6
uniprot id: A0A8B7ET33
uniprot id: A0A8B7X1E4
uniprot id: A0A8B7X1G6
uniprot id: A0A8B7X1Y4
uniprot id: A0A8B7X362
uniprot id: A0A8C5V9J5
uniprot id: A0A8C5XQS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

30608:JAKMIP2
gene id: 30608:JAKMIP2
uniprot id: A0A8B7H0P9
uniprot id: A0A8B7H0V8
uniprot id: A0A8C5VIW1
uniprot id: A0A8C5XNJ3
names: Similarity
messages: Belongs to the JAKMIP family.

30608:ERCC3
gene id: 30608:ERCC3
uniprot id: A0A8C5UW12
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

30608:CD47
gene id: 30608:CD47
uniprot id: A0A8B7X667
uniprot id: A0A8B7X670
uniprot id: A0A8B7X6V1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:RELL2
gene id: 30608:RELL2
uniprot id: A0A8B7F8X4
names: Similarity
messages: Belongs to the RELT family.

30608:TXNDC5
gene id: 30608:TXNDC5
uniprot id: A0A8B7FLI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

30608:LOC105874754
gene id: 30608:LOC105874754
uniprot id: A0A8B7WY56
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:TMED6
gene id: 30608:TMED6
uniprot id: A0A8B7ERZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:LOC105879067
gene id: 30608:LOC105879067
uniprot id: A0A8B7HCC5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

30608:FAM193B
gene id: 30608:FAM193B
uniprot id: A0A8B7HXA6
uniprot id: A0A8B7HXB1
uniprot id: A0A8B7HXB7
uniprot id: A0A8B7HXD1
uniprot id: A0A8B7HZD8
uniprot id: A0A8B7HZE3
uniprot id: A0A8B7HZW2
uniprot id: A0A8B7HZW7
names: Similarity
messages: Belongs to the FAM193 family.

30608:PIAS2
gene id: 30608:PIAS2
uniprot id: A0A8B7EZC6
uniprot id: A0A8B7EZD0
uniprot id: A0A8B7EZD4
uniprot id: A0A8B7F152
uniprot id: A0A8B7F1K9
uniprot id: A0A8B7WS99
names: Similarity
messages: Belongs to the PIAS family.

30608:LOC105877669
gene id: 30608:LOC105877669
uniprot id: A0A8B7H8K4
names: Subcellular Location Annotation
messages: Membrane

30608:TMEM132E
gene id: 30608:TMEM132E
uniprot id: A0A8B7I8V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

30608:LOC105855726
gene id: 30608:LOC105855726
uniprot id: A0A8C5XGK3
names: Similarity
messages: Belongs to the NipSnap family.

30608:LOC105860128
gene id: 30608:LOC105860128
uniprot id: A0A8B7EXJ3
uniprot id: A0A8B7WLC3
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:POLR1E
gene id: 30608:POLR1E
uniprot id: A0A8C5VIK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

30608:PLA2G10
gene id: 30608:PLA2G10
uniprot id: A0A8B7EB85
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

30608:CXCR4
gene id: 30608:CXCR4
uniprot id: A0A8B7ENJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell junction
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: Lysosome
messages: Membrane

30608:NFS1
gene id: 30608:NFS1
uniprot id: A0A8B7FNN6
uniprot id: A0A8C5V9D8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

30608:SHROOM4
gene id: 30608:SHROOM4
uniprot id: A0A8B7FGQ8
uniprot id: A0A8B7FGS8
uniprot id: A0A8B7FGX7
uniprot id: A0A8B7FGY2
uniprot id: A0A8B7FHZ0
uniprot id: A0A8C5VY36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

30608:WNT3
gene id: 30608:WNT3
uniprot id: A0A8C5VFQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

30608:VWA2
gene id: 30608:VWA2
uniprot id: A0A8B7GWU5
uniprot id: A0A8B7GYN2
uniprot id: A0A8C5VBF2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:HN1
gene id: 30608:HN1
uniprot id: A0A8B7HBN9
uniprot id: A0A8B7HBP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

30608:MRGBP
gene id: 30608:MRGBP
uniprot id: A0A8C5XZ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Nucleus

30608:ORMDL3
gene id: 30608:ORMDL3
uniprot id: A0A8B7GFX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Interacts with SPTLC1.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling.

30608:ADH4
gene id: 30608:ADH4
uniprot id: A0A8B7EI19
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-II subfamily.

30608:NDUFV1
gene id: 30608:NDUFV1
uniprot id: A0A8B7FUF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

30608:EVX1
gene id: 30608:EVX1
uniprot id: A0A8B7GYV5
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105884115
gene id: 30608:LOC105884115
uniprot id: A0A8B7HYG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:RBP1
gene id: 30608:RBP1
uniprot id: A0A8B7G694
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

30608:LOC105862535
gene id: 30608:LOC105862535
uniprot id: A0A8B7F8U4
uniprot id: A0A8B7WRA3
uniprot id: A0A8B7WRA7
uniprot id: A0A8B7WRA9
uniprot id: A0A8B7WRB0
uniprot id: A0A8B7WRB2
uniprot id: A0A8B7WRB5
uniprot id: A0A8B7WRC0
uniprot id: A0A8B7WRC5
uniprot id: A0A8B7WRC8
uniprot id: A0A8B7WRD5
uniprot id: A0A8B7WRD7
uniprot id: A0A8B7WSR3
uniprot id: A0A8B7WSR7
uniprot id: A0A8B7WSS2
uniprot id: A0A8C5V033
uniprot id: A0A8C5VDY6
uniprot id: A0A8C5XIP1
uniprot id: A0A8C5XM56
uniprot id: A0A8C5XME2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

30608:CKAP2
gene id: 30608:CKAP2
uniprot id: A0A8B7HKR7
uniprot id: A0A8B7HKS1
uniprot id: A0A8B7HLZ7
names: Similarity
messages: Belongs to the CKAP2 family.

30608:LOC105855931
gene id: 30608:LOC105855931
uniprot id: A0A8B7EDX6
uniprot id: A0A8B7EEJ9
uniprot id: A0A8B7EEL7
uniprot id: A0A8B7EGJ7
uniprot id: A0A8C5V5Y3
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

30608:CSGALNACT1
gene id: 30608:CSGALNACT1
uniprot id: A0A8C5XKP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

30608:ZNF396
gene id: 30608:ZNF396
uniprot id: A0A8B7ESZ7
names: Subcellular Location Annotation
messages: Nucleus

30608:SLC9A1
gene id: 30608:SLC9A1
uniprot id: A0A8B7FDA5
uniprot id: A0A8B7FE51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
messages: Membrane

30608:GALR2
gene id: 30608:GALR2
uniprot id: A0A8B7HEK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:LOC105885895
gene id: 30608:LOC105885895
uniprot id: A0A8B7I6U9
names: Similarity
messages: Belongs to the cornifin (SPRR) family.

30608:AGAP2
gene id: 30608:AGAP2
uniprot id: A0A8B7H7R7
uniprot id: A0A8C5VYK2
uniprot id: A0A8C6EFV9
names: Similarity
messages: Belongs to the centaurin gamma-like family.

30608:STAT3
gene id: 30608:STAT3
uniprot id: A0A8B7ETY6
uniprot id: A0A8B7ETY9
uniprot id: A0A8B7ETZ0
uniprot id: A0A8B7EVY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

30608:ARL8B
gene id: 30608:ARL8B
uniprot id: A0A8B7G3C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Synapse
messages: axon
messages: spindle

30608:ITPRIPL1
gene id: 30608:ITPRIPL1
uniprot id: A0A8B7HW52
uniprot id: A0A8B7HW64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

30608:CFAP126
gene id: 30608:CFAP126
uniprot id: A0A8B7GMA1
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the Flattop family.

30608:TAS2R8
gene id: 30608:TAS2R8
uniprot id: A0A8B7ER52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

30608:LOC105869332
gene id: 30608:LOC105869332
uniprot id: A0A8B7XFY8
names: Similarity
messages: Belongs to the AKAP110 family.

30608:YWHAB
gene id: 30608:YWHAB
uniprot id: A0A8C5VCL8
names: Similarity
messages: Belongs to the 14-3-3 family.

30608:LOC105855455
gene id: 30608:LOC105855455
uniprot id: A0A8B7EC18
uniprot id: A0A8B7ECM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

30608:ARHGAP33
gene id: 30608:ARHGAP33
uniprot id: A0A8B7H2K2
uniprot id: A0A8B7H2K4
uniprot id: A0A8B7H2K6
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

30608:PGPEP1L
gene id: 30608:PGPEP1L
uniprot id: A0A8B7GCY6
names: Similarity
messages: Belongs to the peptidase C15 family.

30608:COQ8B
gene id: 30608:COQ8B
uniprot id: A0A8B7H1P6
uniprot id: A0A8B7H3K4
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

30608:LOC105869395
gene id: 30608:LOC105869395
uniprot id: A0A8B7G3B0
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:LOC105867899
gene id: 30608:LOC105867899
uniprot id: A0A8B7FWJ3
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:KCNK3
gene id: 30608:KCNK3
uniprot id: A0A8B7HZE0
uniprot id: A0A8B7I1F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

30608:HOXA2
gene id: 30608:HOXA2
uniprot id: A0A8B7GYS0
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105879761
gene id: 30608:LOC105879761
uniprot id: A0A8B7HFP4
names: Similarity
messages: Belongs to the cystatin family.

30608:SLC35B4
gene id: 30608:SLC35B4
uniprot id: A0A8B7EKQ8
uniprot id: A0A8B7ELN4
uniprot id: A0A8B7XBY3
uniprot id: A0A8C5UMC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

30608:LOC105883429
gene id: 30608:LOC105883429
uniprot id: A0A8B7HV44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NQO1
gene id: 30608:NQO1
uniprot id: A0A8B7ERV4
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

30608:SLC37A1
gene id: 30608:SLC37A1
uniprot id: A0A8B7HCJ6
uniprot id: A0A8B7WXW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.
messages: Membrane

30608:TDO2
gene id: 30608:TDO2
uniprot id: A0A8C5V3E1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:TAS2R38
gene id: 30608:TAS2R38
uniprot id: I0CKF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane
messages: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.

30608:HSPA4
gene id: 30608:HSPA4
uniprot id: A0A8B7WSX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Interacts with TJP1/ZO-1.

30608:LOC105885422
gene id: 30608:LOC105885422
uniprot id: A0A8B7I4M5
uniprot id: A0A8B7I6N0
uniprot id: A0A8B7I7R6
names: Similarity
messages: Belongs to the SH3BGR family.

30608:NMBR
gene id: 30608:NMBR
uniprot id: A0A8B7EU49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NEFH
gene id: 30608:NEFH
uniprot id: A0A8B7G9W6
uniprot id: A0A8B7GA76
uniprot id: A0A8B7GAH5
uniprot id: A0A8B7WTB6
uniprot id: A0A8B7WTB7
uniprot id: A0A8B7WTC0
uniprot id: A0A8B7WTC4
uniprot id: A0A8B7WTH1
uniprot id: A0A8B7WTI2
uniprot id: A0A8B7WTN9
uniprot id: A0A8B7WUX1
uniprot id: A0A8B7WUX6
names: Similarity
messages: Belongs to the intermediate filament family.

30608:LOC105855727
gene id: 30608:LOC105855727
uniprot id: A0A8B7ED37
uniprot id: A0A8B7EDM4
uniprot id: A0A8C5UKW5
names: Similarity
messages: Belongs to the NipSnap family.

30608:FAM160B2
gene id: 30608:FAM160B2
uniprot id: A0A8B7EKB6
names: Similarity
messages: Belongs to the FHIP family.

30608:HS3ST6
gene id: 30608:HS3ST6
uniprot id: A0A8C5V2J0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:BEST3
gene id: 30608:BEST3
uniprot id: A0A8B7I0R8
uniprot id: A0A8B7I0S6
uniprot id: A0A8B7I2V2
uniprot id: A0A8C5YF28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Membrane

30608:LOC105879475
gene id: 30608:LOC105879475
uniprot id: A0A8B7WY75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

30608:AGBL1
gene id: 30608:AGBL1
uniprot id: A0A8B7H2Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

30608:LOC105864639
gene id: 30608:LOC105864639
uniprot id: A0A8B7FHW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105864453
gene id: 30608:LOC105864453
uniprot id: A0A8B7X968
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

30608:MOGS
gene id: 30608:MOGS
uniprot id: A0A8C5XC83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

30608:TMEM234
gene id: 30608:TMEM234
uniprot id: A0A8B7GET6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM234 family.
messages: Membrane

30608:SLC39A2
gene id: 30608:SLC39A2
uniprot id: A0A8B7FII4
uniprot id: A0A8B7FJV0
names: Subcellular Location Annotation
messages: Membrane

30608:CNOT7
gene id: 30608:CNOT7
uniprot id: A0A8C5VZW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

30608:LOC105855792
gene id: 30608:LOC105855792
uniprot id: A0A8B7EG21
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

30608:NOTCH2
gene id: 30608:NOTCH2
uniprot id: A0A8B7G553
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

30608:NAA10
gene id: 30608:NAA10
uniprot id: A0A8B7FU31
uniprot id: A0A8B7FU33
uniprot id: A0A8B7FU75
uniprot id: A0A8C5WBU3
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

30608:TRMT112
gene id: 30608:TRMT112
uniprot id: A0A8C5VCE5
names: Similarity
messages: Belongs to the TRM112 family.

30608:AP4M1
gene id: 30608:AP4M1
uniprot id: A0A8B7FY59
uniprot id: A0A8B7FZB9
uniprot id: A0A8C5XKU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. Within AP-4, the mu-type subunit AP4M1 is directly involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos. The adaptor protein complex 4 (AP-4) may also recognize other types of sorting signal.
messages: Early endosome
messages: trans-Golgi network membrane

30608:AREG
gene id: 30608:AREG
uniprot id: A0A8B7EZQ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:BANF2
gene id: 30608:BANF2
uniprot id: A0A8C5V7L7
names: Subcellular Location Annotation
messages: Nucleus

30608:C9H15orf40
gene id: 30608:C9H15orf40
uniprot id: A0A8B7G8E6
uniprot id: A0A8B7G8L4
uniprot id: A0A8B7G9J0
uniprot id: A0A8C5VS14
names: Similarity
messages: Belongs to the UPF0235 family.

30608:ADRA2B
gene id: 30608:ADRA2B
uniprot id: A0A8B7HW59
uniprot id: A0A8B7HY85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
messages: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2B sub-subfamily.
messages: Cell membrane
messages: Membrane

30608:ZCCHC8
gene id: 30608:ZCCHC8
uniprot id: A0A8B7WT09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC8 family.
messages: nucleoplasm

30608:LOC105883423
gene id: 30608:LOC105883423
uniprot id: A0A8B7HX88
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105864413
gene id: 30608:LOC105864413
uniprot id: A0A8B7FH90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PIH1D2
gene id: 30608:PIH1D2
uniprot id: A0A8C5XHZ3
names: Similarity
messages: Belongs to the PIH1 family.

30608:AK3
gene id: 30608:AK3
uniprot id: A0A8B7EFZ1
uniprot id: A0A8B7EHX6
uniprot id: A0A8B7EHY4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

30608:PAH
gene id: 30608:PAH
uniprot id: A0A8B7GX53
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

30608:LOC105883835
gene id: 30608:LOC105883835
uniprot id: A0A8B7HX59
names: Subcellular Location Annotation
messages: Membrane

30608:DLGAP2
gene id: 30608:DLGAP2
uniprot id: A0A8B7I0Z2
uniprot id: A0A8B7I0Z7
uniprot id: A0A8B7I109
uniprot id: A0A8B7I114
uniprot id: A0A8B7I345
uniprot id: A0A8B7I350
uniprot id: A0A8B7I3U4
uniprot id: A0A8B7I3U9
uniprot id: A0A8C5VBR4
names: Similarity
messages: Belongs to the SAPAP family.

30608:TGFB2
gene id: 30608:TGFB2
uniprot id: A0A8B7G0B6
uniprot id: A0A8B7G179
uniprot id: A0A8C5Y026
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

30608:HMGN5
gene id: 30608:HMGN5
uniprot id: A0A8B7WZZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

30608:ANP32A
gene id: 30608:ANP32A
uniprot id: A0A8B7GMK9
uniprot id: A0A8C5VPF4
names: Similarity
messages: Belongs to the ANP32 family.

30608:DEFB123
gene id: 30608:DEFB123
uniprot id: A0A8B7WQG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

30608:LOC105875154
gene id: 30608:LOC105875154
uniprot id: A0A8B7XDH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:KIF16B
gene id: 30608:KIF16B
uniprot id: A0A8B7G0E4
uniprot id: A0A8B7WQK1
uniprot id: A0A8B7WQK2
uniprot id: A0A8B7WQK3
uniprot id: A0A8B7WQK6
uniprot id: A0A8B7WQK7
uniprot id: A0A8B7WQK9
uniprot id: A0A8B7WQP7
uniprot id: A0A8B7WQQ2
uniprot id: A0A8B7WS23
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:WDR46
gene id: 30608:WDR46
uniprot id: A0A8B7I797
names: Subcellular Location Annotation
messages: nucleolus

30608:RPRD2
gene id: 30608:RPRD2
uniprot id: A0A8B7GJH3
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

30608:EBF1
gene id: 30608:EBF1
uniprot id: A0A8B7WV43
uniprot id: A0A8B7WV49
uniprot id: A0A8B7WVD2
uniprot id: A0A8B7WVD7
uniprot id: A0A8B7WVP2
uniprot id: A0A8B7WVP7
uniprot id: A0A8B7WWS1
uniprot id: A0A8B7WWS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

30608:ADI1
gene id: 30608:ADI1
uniprot id: A0A8B7G895
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. Also down-regulates cell migration mediated by MMP14.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer. Interacts with MMP14.
messages: Nucleus

30608:LOC105866295
gene id: 30608:LOC105866295
uniprot id: A0A8B7FQ67
uniprot id: A0A8B7FR69
uniprot id: D1GEY1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:BTBD10
gene id: 30608:BTBD10
uniprot id: A0A8B7HGF6
uniprot id: A0A8B7HGF9
uniprot id: A0A8B7HJ32
names: Subcellular Location Annotation
messages: Cytoplasm

30608:REEP4
gene id: 30608:REEP4
uniprot id: A0A8C5VHH7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:CSPG4
gene id: 30608:CSPG4
uniprot id: A0A8B7ECD0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:OSGEPL1
gene id: 30608:OSGEPL1
uniprot id: A0A8B7H9J9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Monomer.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

30608:ELL3
gene id: 30608:ELL3
uniprot id: A0A8B7GHT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

30608:LOC105864507
gene id: 30608:LOC105864507
uniprot id: A0A8B7WWS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

30608:ALG14
gene id: 30608:ALG14
uniprot id: A0A8B7I6B7
uniprot id: A0A8C5VGL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG14 family.
messages: Membrane
messages: Nucleus membrane

30608:SLC26A9
gene id: 30608:SLC26A9
uniprot id: A0A8B7G139
uniprot id: A0A8B7G152
uniprot id: A0A8C5XL75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LOC105878820
gene id: 30608:LOC105878820
uniprot id: A0A8B7HB84
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105864490
gene id: 30608:LOC105864490
uniprot id: A0A8B7FHA2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Secreted

30608:MIEF2
gene id: 30608:MIEF2
uniprot id: A0A8C5VC22
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

30608:LOC105858727
gene id: 30608:LOC105858727
uniprot id: A0A8B7ER02
uniprot id: A0A8B7ET37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:IL15RA
gene id: 30608:IL15RA
uniprot id: A0A8B7ENY1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:HYAL1
gene id: 30608:HYAL1
uniprot id: A0A8C5V4S7
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

30608:SEMA3E
gene id: 30608:SEMA3E
uniprot id: A0A8C5VDR9
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:B4GALT4
gene id: 30608:B4GALT4
uniprot id: A0A8B7HG25
uniprot id: A0A8B7HG54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

30608:PHACTR2
gene id: 30608:PHACTR2
uniprot id: A0A8B7FHC0
uniprot id: A0A8B7FHD2
uniprot id: A0A8B7FHI3
uniprot id: A0A8B7FHJ3
uniprot id: A0A8B7FHK6
uniprot id: A0A8B7X511
uniprot id: A0A8B7X6X1
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

30608:SPI1
gene id: 30608:SPI1
uniprot id: A0A8B7I2C5
uniprot id: A0A8B7I4D6
uniprot id: A0A8B7I4E6
uniprot id: A0A8B7I5C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:BEST1
gene id: 30608:BEST1
uniprot id: A0A8C5XUE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Membrane

30608:LOC105884086
gene id: 30608:LOC105884086
uniprot id: A0A8B7I143
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TSC22D1
gene id: 30608:TSC22D1
uniprot id: A0A8B7HKY2
uniprot id: A0A8B7HKY9
uniprot id: A0A8B7HM66
uniprot id: A0A8B7XFZ9
uniprot id: A0A8C5VLF2
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

30608:HTR3A
gene id: 30608:HTR3A
uniprot id: A0A8B7F6Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

30608:TPST1
gene id: 30608:TPST1
uniprot id: A0A8B7GAH7
uniprot id: A0A8B7GAX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

30608:LOC105856043
gene id: 30608:LOC105856043
uniprot id: A0A8B7EEJ8
uniprot id: A0A8B7EEK8
uniprot id: A0A8B7EEM3
uniprot id: A0A8B7EFB3
names: Subcellular Location Annotation
messages: Nucleus

30608:YKT6
gene id: 30608:YKT6
uniprot id: A0A8C5YCR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

30608:LACTB2
gene id: 30608:LACTB2
uniprot id: A0A8B7GU42
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

30608:KCNG4
gene id: 30608:KCNG4
uniprot id: A0A8B7EH91
names: Subcellular Location Annotation
messages: Membrane

30608:DDX5
gene id: 30608:DDX5
uniprot id: A0A8B7F525
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.

30608:HOXD12
gene id: 30608:HOXD12
uniprot id: A0A8C5UNB9
names: Subcellular Location Annotation
messages: Nucleus

30608:GGNBP2
gene id: 30608:GGNBP2
uniprot id: A0A8B7HCT9
uniprot id: A0A8B7HD39
uniprot id: A0A8B7HD58
uniprot id: A0A8B7HDP0
uniprot id: A0A8C5VDD1
uniprot id: A0A8C5VDL7
names: Function
messages: May be involved in spermatogenesis.

30608:EID2B
gene id: 30608:EID2B
uniprot id: A0A8B7H357
names: Subcellular Location Annotation
messages: Nucleus

30608:CES3
gene id: 30608:CES3
uniprot id: A0A8B7ESI0
uniprot id: A0A8B7ESI1
uniprot id: A0A8B7ESI3
uniprot id: A0A8B7EUB4
uniprot id: A0A8B7EUB9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

30608:SEMA4A
gene id: 30608:SEMA4A
uniprot id: A0A8B7GKH8
names: Similarity
messages: Belongs to the semaphorin family.

30608:CSF3
gene id: 30608:CSF3
uniprot id: A0A8B7WML6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
messages: Secreted

30608:GLB1
gene id: 30608:GLB1
uniprot id: A0A8C5YGM7
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

30608:PHACTR4
gene id: 30608:PHACTR4
uniprot id: A0A8B7FD04
uniprot id: A0A8B7FD19
uniprot id: A0A8B7FD25
uniprot id: A0A8B7FD82
uniprot id: A0A8B7WLH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway.
messages: lamellipodium

30608:TUSC3
gene id: 30608:TUSC3
uniprot id: A0A8B7WSU2
uniprot id: A0A8B7WU94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:TMEM255A
gene id: 30608:TMEM255A
uniprot id: A0A8B7EIT2
uniprot id: A0A8C5V1H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

30608:RRAGB
gene id: 30608:RRAGB
uniprot id: A0A8B7FT76
uniprot id: A0A8B7FTA4
uniprot id: A0A8B7FTX9
uniprot id: A0A8C6EL39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

30608:LOC105873836
gene id: 30608:LOC105873836
uniprot id: A0A8B7GNM5
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

30608:TM4SF20
gene id: 30608:TM4SF20
uniprot id: A0A8B7FAF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

30608:SLC1A2
gene id: 30608:SLC1A2
uniprot id: A0A8C5XLI3
uniprot id: A0A8C5XX87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

30608:GCNT3
gene id: 30608:GCNT3
uniprot id: A0A8B7HLK3
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

30608:LOC105875151
gene id: 30608:LOC105875151
uniprot id: A0A8B7GWN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TAC4
gene id: 30608:TAC4
uniprot id: A0A8B7I344
uniprot id: A0A8B7I356
uniprot id: A0A8B7I556
names: Similarity
messages: Belongs to the tachykinin family.

30608:OVCA2
gene id: 30608:OVCA2
uniprot id: A0A8B7EP33
names: Similarity
messages: Belongs to the LovG family.

30608:KAT2B
gene id: 30608:KAT2B
uniprot id: A0A8B7XCS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus
messages: centrosome

30608:LYZL6
gene id: 30608:LYZL6
uniprot id: A0A8B7HW18
uniprot id: A0A8B7HW31
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

30608:LOC109730586
gene id: 30608:LOC109730586
uniprot id: A0A8B7X3U6
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

30608:RAB3GAP1
gene id: 30608:RAB3GAP1
uniprot id: A0A8B7EL82
uniprot id: A0A8B7EMK4
uniprot id: A0A8B7ENI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP catalytic subunit family.
messages: Cytoplasm

30608:SLC35C1
gene id: 30608:SLC35C1
uniprot id: A0A8B7I460
uniprot id: A0A8B7I493
uniprot id: A0A8B7I4A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPT transporter family. SLC35C subfamily.
messages: Membrane

30608:IFNK
gene id: 30608:IFNK
uniprot id: A0A8B7XDB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

30608:DDAH2
gene id: 30608:DDAH2
uniprot id: A0A8B7EPW4
uniprot id: A0A8C5VVG2
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

30608:MYT1L
gene id: 30608:MYT1L
uniprot id: A0A8B7G879
uniprot id: A0A8B7G880
uniprot id: A0A8B7G883
uniprot id: A0A8B7G885
uniprot id: A0A8B7G888
uniprot id: A0A8B7G8F2
uniprot id: A0A8B7G8F8
uniprot id: A0A8B7G8X0
uniprot id: A0A8B7G8X3
uniprot id: A0A8B7G9C9
uniprot id: A0A8B7G9D4
uniprot id: A0A8B7X943
uniprot id: A0A8B7X951
uniprot id: A0A8B7X9T5
uniprot id: A0A8B7XAS4
uniprot id: A0A8B7XB59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

30608:ESR1
gene id: 30608:ESR1
uniprot id: A0A8B7X5N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

30608:GDPD2
gene id: 30608:GDPD2
uniprot id: A0A8B7EBX7
uniprot id: A0A8C5VT14
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

30608:SHOX
gene id: 30608:SHOX
uniprot id: A0A8C5V4B2
names: Subcellular Location Annotation
messages: Nucleus

30608:COPS5
gene id: 30608:COPS5
uniprot id: A0A8B7EXL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: synaptic vesicle

30608:NUP133
gene id: 30608:NUP133
uniprot id: A0A8B7WP06
uniprot id: A0A8B7WQA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin Nup133 family.
messages: nuclear pore complex

30608:SLC10A2
gene id: 30608:SLC10A2
uniprot id: A0A8B7FHN6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane
messages: Monomer and homodimer.

30608:FAM212B
gene id: 30608:FAM212B
uniprot id: A0A8B7HDU3
uniprot id: A0A8C5VHS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

30608:LOC105857653
gene id: 30608:LOC105857653
uniprot id: A0A8B7EL96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105872944
gene id: 30608:LOC105872944
uniprot id: A0A8B7GJI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TPM2
gene id: 30608:TPM2
uniprot id: A0A8B7GQI7
uniprot id: A0A8B7GQT2
uniprot id: A0A8B7GQX1
uniprot id: A0A8C5W2X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

30608:AK2
gene id: 30608:AK2
uniprot id: A0A8B7XDD0
uniprot id: A0A8B7XEP0
uniprot id: A0A8B7XF33
uniprot id: A0A8B7XFM4
names: Similarity
messages: Belongs to the adenylate kinase family.

30608:STAB1
gene id: 30608:STAB1
uniprot id: A0A8B7GUD0
uniprot id: A0A8B7WLV9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:PNLIPRP1
gene id: 30608:PNLIPRP1
uniprot id: A0A8B7H1W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

30608:MMP8
gene id: 30608:MMP8
uniprot id: A0A8C5V1S2
names: Similarity
messages: Belongs to the peptidase M10A family.

30608:GNG12
gene id: 30608:GNG12
uniprot id: A0A8B7X9I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

30608:TBP
gene id: 30608:TBP
uniprot id: A0A8C5UZP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

30608:DCP1B
gene id: 30608:DCP1B
uniprot id: A0A8B7F4S1
uniprot id: A0A8B7F4S5
uniprot id: A0A8B7F4S9
names: Similarity
messages: Belongs to the DCP1 family.

30608:LETM2
gene id: 30608:LETM2
uniprot id: A0A8B7G826
uniprot id: A0A8B7G8J9
names: Subcellular Location Annotation
messages: Membrane

30608:NDUFA3
gene id: 30608:NDUFA3
uniprot id: A0A8C5UL97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA3 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Membrane
messages: Mitochondrion inner membrane

30608:CSF1R
gene id: 30608:CSF1R
uniprot id: A0A8B7ERV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

30608:SLA
gene id: 30608:SLA
uniprot id: A0A8B7HSH8
uniprot id: A0A8C5Y7B9
names: Subcellular Location Annotation
messages: Cytoplasm

30608:TCEA3
gene id: 30608:TCEA3
uniprot id: A0A8C5USD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

30608:CPAMD8
gene id: 30608:CPAMD8
uniprot id: A0A8B7WVG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

30608:PMM1
gene id: 30608:PMM1
uniprot id: A0A8C5VTY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

30608:LDLRAD2
gene id: 30608:LDLRAD2
uniprot id: A0A8B7GML1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105883029
gene id: 30608:LOC105883029
uniprot id: A0A8B7HTI6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

30608:NOC2L
gene id: 30608:NOC2L
uniprot id: A0A8C5UU11
names: Similarity
messages: Belongs to the NOC2 family.

30608:LOC109730981
gene id: 30608:LOC109730981
uniprot id: A0A8B7X967
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6c family.

30608:TAF1A
gene id: 30608:TAF1A
uniprot id: A0A8B7E9X9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. In the complex interacts directly with TBP, TAF1A and TAF1B. Interaction of the SL1/TIF-IB subunits with TBP excludes interaction of TBP with the transcription factor IID (TFIID) subunits.
messages: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
messages: Nucleus

30608:LOXHD1
gene id: 30608:LOXHD1
uniprot id: A0A8B7I6M0
uniprot id: A0A8B7I7Q4
uniprot id: A0A8C5UJS0
uniprot id: A0A8C5VUS9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SMC1B
gene id: 30608:SMC1B
uniprot id: A0A8B7FVF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

30608:UBP1
gene id: 30608:UBP1
uniprot id: A0A8B7WQC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

30608:KCNT1
gene id: 30608:KCNT1
uniprot id: A0A8B7HJG8
uniprot id: A0A8B7HJH0
uniprot id: A0A8B7HJH4
uniprot id: A0A8B7HKL2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:PIGV
gene id: 30608:PIGV
uniprot id: A0A8C6EKZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

30608:MIXL1
gene id: 30608:MIXL1
uniprot id: A0A8B7FEC2
names: Subcellular Location Annotation
messages: Nucleus

30608:KRT40
gene id: 30608:KRT40
uniprot id: A0A8C5V0Q8
names: Similarity
messages: Belongs to the intermediate filament family.

30608:LOC105872240
gene id: 30608:LOC105872240
uniprot id: A0A8B7XEZ2
names: Subcellular Location Annotation
messages: Peroxisome

30608:HOXD9
gene id: 30608:HOXD9
uniprot id: A0A8B7FJT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

30608:LPIN1
gene id: 30608:LPIN1
uniprot id: A0A8B7X754
names: Similarity
messages: Belongs to the lipin family.

30608:LOC105862829
gene id: 30608:LOC105862829
uniprot id: A0A8B7X7F7
uniprot id: A0A8B7X944
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with TOGARAM1, CCDC66, CEP104, CSPP1 and CEP290.
messages: centriole
messages: cilium
messages: cilium basal body

30608:ISCU
gene id: 30608:ISCU
uniprot id: A0A8B7FSJ9
uniprot id: A0A8B7FTG9
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

30608:PSD2
gene id: 30608:PSD2
uniprot id: A0A8B7F8R8
uniprot id: A0A8B7F8R9
uniprot id: A0A8B7F8W7
names: Subcellular Location Annotation
messages: ruffle membrane

30608:SERINC2
gene id: 30608:SERINC2
uniprot id: A0A8B7GET1
uniprot id: A0A8C5VNX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

30608:DEFB128
gene id: 30608:DEFB128
uniprot id: A0A8B7WRV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

30608:CARM1
gene id: 30608:CARM1
uniprot id: A0A8B7WWD7
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105862258
gene id: 30608:LOC105862258
uniprot id: A0A8B7WV47
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

30608:VANGL2
gene id: 30608:VANGL2
uniprot id: A0A8B7WZ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

30608:TECR
gene id: 30608:TECR
uniprot id: A0A8B7FWL9
uniprot id: A0A8C6EHJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

30608:PUS1
gene id: 30608:PUS1
uniprot id: A0A8B7HEB3
uniprot id: A0A8B7HGL9
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

30608:LOC105864528
gene id: 30608:LOC105864528
uniprot id: A0A8B7FIR4
names: Subcellular Location Annotation
messages: Membrane

30608:SH3GL2
gene id: 30608:SH3GL2
uniprot id: A0A8B7GQ74
uniprot id: A0A8B7GRA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

30608:LOC105858296
gene id: 30608:LOC105858296
uniprot id: A0A8C5XZE5
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:CD9
gene id: 30608:CD9
uniprot id: A0A8C5UVK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Membrane
messages: extracellular exosome

30608:ACER3
gene id: 30608:ACER3
uniprot id: A0A8B7EYK4
uniprot id: A0A8B7F0C8
uniprot id: A0A8B7F0P5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:CLCN7
gene id: 30608:CLCN7
uniprot id: A0A8B7EUP3
uniprot id: A0A8C5VMA9
uniprot id: A0A8C5VSW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

30608:PDK4
gene id: 30608:PDK4
uniprot id: A0A8C5XZ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

30608:GPI
gene id: 30608:GPI
uniprot id: A0A8B7H2X0
names: Similarity
messages: Belongs to the GPI family.

30608:NCDN
gene id: 30608:NCDN
uniprot id: A0A8B7GE88
uniprot id: A0A8C5URW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurochondrin family.
messages: Postsynapse

30608:BBOX1
gene id: 30608:BBOX1
uniprot id: A0A8C5UQ61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-BBH/TMLD family.
messages: Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
messages: Cytoplasm

30608:CACNB2
gene id: 30608:CACNB2
uniprot id: A0A8B7F852
uniprot id: A0A8B7F854
uniprot id: A0A8B7F859
uniprot id: A0A8B7F860
uniprot id: A0A8B7F896
uniprot id: A0A8B7F8A0
uniprot id: A0A8B7F8G5
uniprot id: A0A8C5V9V2
uniprot id: A0A8C5VIL9
uniprot id: A0A8C5WBM5
uniprot id: A0A8C5XR98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
messages: sarcolemma

30608:LOC105880312
gene id: 30608:LOC105880312
uniprot id: A0A8B7HHH9
names: Caution
names: Similarity
messages: Belongs to the DMBT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:NPM1
gene id: 30608:NPM1
uniprot id: A0A8C5YAS8
uniprot id: A0A8C6EHK9
names: Similarity
messages: Belongs to the nucleoplasmin family.

30608:LOC105862414
gene id: 30608:LOC105862414
uniprot id: A0A8B7F8J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ABCD3
gene id: 30608:ABCD3
uniprot id: A0A8B7I667
uniprot id: A0A8C5VH68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

30608:ZCCHC17
gene id: 30608:ZCCHC17
uniprot id: A0A8B7GE24
uniprot id: A0A8B7GEK6
names: Subcellular Location Annotation
messages: nucleolus

30608:RUVBL2
gene id: 30608:RUVBL2
uniprot id: A0A8B7FM16
uniprot id: A0A8C5XLT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

30608:C24H19orf66
gene id: 30608:C24H19orf66
uniprot id: A0A8C5VBP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHFL family.
messages: Nucleus
messages: P-body

30608:TUSC5
gene id: 30608:TUSC5
uniprot id: A0A8B7EMB7
names: Similarity
messages: Belongs to the CD225/Dispanin family.

30608:SLC9A8
gene id: 30608:SLC9A8
uniprot id: A0A8B7GFU3
uniprot id: A0A8B7GGA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Membrane

30608:FER
gene id: 30608:FER
uniprot id: A0A8B7I4E8
uniprot id: A0A8B7I6F2
uniprot id: A0A8C5V808
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: Cell membrane
messages: cytoskeleton

30608:POLR2L
gene id: 30608:POLR2L
uniprot id: A0A8B7X478
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

30608:LOC105862427
gene id: 30608:LOC105862427
uniprot id: A0A8B7F8K3
names: Subcellular Location Annotation
messages: Membrane

30608:UCHL5
gene id: 30608:UCHL5
uniprot id: A0A8B7GWF0
uniprot id: A0A8B7GWF1
uniprot id: A0A8B7GWH9
uniprot id: A0A8B7GY73
uniprot id: A0A8B7GY80
names: Similarity
messages: Belongs to the peptidase C12 family.

30608:LOC105865443
gene id: 30608:LOC105865443
uniprot id: A0A8B7X5D4
names: Similarity
messages: Belongs to the KHDC1 family.

30608:WIPI2
gene id: 30608:WIPI2
uniprot id: A0A8B7FYZ8
uniprot id: A0A8B7FYZ9
uniprot id: A0A8B7FZ32
uniprot id: A0A8C5XH82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PROPPIN family.
messages: Preautophagosomal structure membrane

30608:ATAT1
gene id: 30608:ATAT1
uniprot id: A0A8B7EBS5
uniprot id: A0A8B7EBS8
uniprot id: A0A8B7EBU7
uniprot id: A0A8B7EC69
uniprot id: A0A8B7ECF0
uniprot id: A0A8B7EEF8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autoacetylation strongly increases tubulin acetylation.
messages: Belongs to the acetyltransferase ATAT1 family.
messages: Component of the BBSome complex. Interacts with AP2 alpha-adaptins, including AP2A2, but not with AP1 gamma-adaptin (AP1G1/AP1G2); this interaction is required for efficient alpha-tubulin acetylation, hence clathrin-coated pits are sites of microtubule acetylation.
messages: Cytoplasm
messages: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.
messages: axon
messages: clathrin-coated pit
messages: cytoskeleton
messages: focal adhesion
messages: spindle

30608:LOC105864740
gene id: 30608:LOC105864740
uniprot id: A0A8B7FIG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:KRT76
gene id: 30608:KRT76
uniprot id: A0A8B7G878
uniprot id: A0A8B7G887
names: Similarity
messages: Belongs to the intermediate filament family.

30608:C2H1orf174
gene id: 30608:C2H1orf174
uniprot id: A0A8C5VD15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0688 family.
messages: Nucleus

30608:SLC7A6
gene id: 30608:SLC7A6
uniprot id: A0A8B7ETT5
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105884677
gene id: 30608:LOC105884677
uniprot id: A0A8B7I0Y4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

30608:LAMA2
gene id: 30608:LAMA2
uniprot id: A0A8B7ECF2
uniprot id: A0A8B7ED11
uniprot id: A0A8C5VDA4
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

30608:NFIL3
gene id: 30608:NFIL3
uniprot id: A0A8B7GZV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock. Protects pro-B cells from programmed cell death.
messages: Belongs to the bZIP family. NFIL3 subfamily.
messages: Homodimer. Binds DNA as a dimer.
messages: Nucleus

30608:NAT9
gene id: 30608:NAT9
uniprot id: A0A8B7HBL2
uniprot id: A0A8B7HBL8
uniprot id: A0A8C5W082
names: Similarity
messages: Belongs to the acetyltransferase family. GNAT subfamily.

30608:FOXA1
gene id: 30608:FOXA1
uniprot id: A0A8C5W3R4
names: Subcellular Location Annotation
messages: Nucleus

30608:RBP7
gene id: 30608:RBP7
uniprot id: A0A8B7X1F4
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

30608:LOC105872381
gene id: 30608:LOC105872381
uniprot id: A0A8B7GH25
names: Subcellular Location Annotation
messages: Membrane

30608:NXPH1
gene id: 30608:NXPH1
uniprot id: A0A8C5XI05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

30608:ISY1
gene id: 30608:ISY1
uniprot id: A0A8B7WWF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

30608:PHYHIPL
gene id: 30608:PHYHIPL
uniprot id: A0A8B7G8N8
uniprot id: A0A8C5Y136
names: Similarity
messages: Belongs to the PHYHIP family.

30608:DSCR3
gene id: 30608:DSCR3
uniprot id: A0A8B7HLC1
uniprot id: A0A8B7HLC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS26 family.
messages: Endosome

30608:CDKAL1
gene id: 30608:CDKAL1
uniprot id: A0A8B7FJY8
uniprot id: A0A8B7FK15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
messages: Endoplasmic reticulum membrane

30608:CDK5RAP1
gene id: 30608:CDK5RAP1
uniprot id: A0A8B7WPU6
names: Similarity
messages: Belongs to the methylthiotransferase family. MiaB subfamily.

30608:DEFB115
gene id: 30608:DEFB115
uniprot id: A0A8B7WQT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

30608:GRID2
gene id: 30608:GRID2
uniprot id: A0A8B7H0L8
uniprot id: A0A8C5UQ59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

30608:LOC105860840
gene id: 30608:LOC105860840
uniprot id: A0A8B7F0M3
uniprot id: A0A8B7F2D1
names: Similarity
messages: Belongs to the paralemmin family.

30608:VAMP3
gene id: 30608:VAMP3
uniprot id: A0A8B7I7J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

30608:FOXD3
gene id: 30608:FOXD3
uniprot id: A0A8B7X0A3
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105880627
gene id: 30608:LOC105880627
uniprot id: A0A8C5XZL0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

30608:GALR3
gene id: 30608:GALR3
uniprot id: A0A8B7EPY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:TAC3
gene id: 30608:TAC3
uniprot id: A0A8B7H7H8
uniprot id: A0A8C5UM05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted

30608:PLAGL2
gene id: 30608:PLAGL2
uniprot id: A0A8B7FQG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

30608:NIPBL
gene id: 30608:NIPBL
uniprot id: A0A8B7EC13
uniprot id: A0A8B7EC30
uniprot id: A0A8B7ECN9
uniprot id: A0A8B7EEQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

30608:LOC105869134
gene id: 30608:LOC105869134
uniprot id: A0A8B7G2E0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

30608:INSL3
gene id: 30608:INSL3
uniprot id: A0A8B7WW18
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Secreted

30608:FAM171B
gene id: 30608:FAM171B
uniprot id: A0A8B7HDD8
uniprot id: A0A8C5Y0T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

30608:EDA
gene id: 30608:EDA
uniprot id: A0A8B7EBK8
uniprot id: A0A8B7EBN3
uniprot id: A0A8B7EC89
uniprot id: A0A8C5V6S7
names: Similarity
messages: Belongs to the tumor necrosis factor family.

30608:KDELR3
gene id: 30608:KDELR3
uniprot id: A0A8C5XBS7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:PPP1R11
gene id: 30608:PPP1R11
uniprot id: A0A8B7EC43
uniprot id: A0A8B7EED3
names: Subunit
messages: Interacts with TLR2 and UBE2D2.

30608:ADGRL4
gene id: 30608:ADGRL4
uniprot id: A0A8B7HX46
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:MAP7D3
gene id: 30608:MAP7D3
uniprot id: A0A8B7FH24
uniprot id: A0A8B7FH58
uniprot id: A0A8B7FHB4
names: Similarity
messages: Belongs to the MAP7 family.

30608:SLC16A1
gene id: 30608:SLC16A1
uniprot id: A0A8B7HAY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane
messages: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

30608:LOC105860067
gene id: 30608:LOC105860067
uniprot id: A0A8B7EZ06
uniprot id: A0A8B7EZ42
uniprot id: A0A8B7WX10
uniprot id: A0A8B7WX12
uniprot id: A0A8B7WXD0
uniprot id: A0A8B7WXT7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

30608:CA14
gene id: 30608:CA14
uniprot id: A0A8B7GJ34
uniprot id: A0A8B7GJF6
uniprot id: A0A8C5YCE1
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

30608:PAX9
gene id: 30608:PAX9
uniprot id: A0A8C5Y431
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with KDM5B.
messages: Nucleus
messages: Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs.

30608:TCTE3
gene id: 30608:TCTE3
uniprot id: A0A8B7HLP1
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

30608:LOC105861795
gene id: 30608:LOC105861795
uniprot id: A0A8B7F5M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

30608:GPR179
gene id: 30608:GPR179
uniprot id: A0A8B7GG46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

30608:CEP44
gene id: 30608:CEP44
uniprot id: A0A8B7GS67
uniprot id: A0A8B7GS69
uniprot id: A0A8B7GSG5
names: Subcellular Location Annotation
messages: Midbody
messages: centriole
messages: spindle pole

30608:LOC105865103
gene id: 30608:LOC105865103
uniprot id: A0A8B7X5L2
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

30608:LOC105875016
gene id: 30608:LOC105875016
uniprot id: A0A8B7X9K8
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

30608:PPEF2
gene id: 30608:PPEF2
uniprot id: A0A8B7EWS5
uniprot id: A0A8B7EYL9
uniprot id: A0A8B7EYM9
names: Similarity
messages: Belongs to the PPP phosphatase family.

30608:HMGB2
gene id: 30608:HMGB2
uniprot id: A0A8B7GS57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

30608:MCM9
gene id: 30608:MCM9
uniprot id: A0A8B7EIU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

30608:URAD
gene id: 30608:URAD
uniprot id: A0A8B7ERM5
uniprot id: A0A8B7ETP5
names: Function
names: Similarity
messages: Belongs to the OHCU decarboxylase family.
messages: Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.

30608:TACC1
gene id: 30608:TACC1
uniprot id: A0A8B7G7X1
uniprot id: A0A8B7G7X5
uniprot id: A0A8B7G7X6
uniprot id: A0A8B7G835
uniprot id: A0A8B7G840
uniprot id: A0A8B7G8L0
uniprot id: A0A8B7G8L5
uniprot id: A0A8B7G908
uniprot id: A0A8B7G913
uniprot id: A0A8B7G918
uniprot id: A0A8B7WSZ2
uniprot id: A0A8C5YC34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: centrosome

30608:RETNLB
gene id: 30608:RETNLB
uniprot id: A0A8C5YFL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistin/FIZZ family.
messages: Secreted

30608:LOC105864600
gene id: 30608:LOC105864600
uniprot id: A0A8B7FHQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105878174
gene id: 30608:LOC105878174
uniprot id: A0A8B7WSZ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:FAM46A
gene id: 30608:FAM46A
uniprot id: A0A8B7GNC2
uniprot id: A0A8C5VMH4
names: Similarity
messages: Belongs to the TENT family.

30608:DOT1L
gene id: 30608:DOT1L
uniprot id: A0A8B7F024
uniprot id: A0A8B7F028
uniprot id: A0A8B7F029
uniprot id: A0A8B7F037
uniprot id: A0A8B7F1U2
uniprot id: A0A8B7F2C9
uniprot id: A0A8C5V7V0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: Histone methyltransferase. Methylates 'Lys-79' of histone H3.
messages: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
messages: Nucleus

30608:TNP2
gene id: 30608:TNP2
uniprot id: A0A8C5UPL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear transition protein 2 family.
messages: Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
messages: nucleolus

30608:MSRB1
gene id: 30608:MSRB1
uniprot id: A0A8B7EWV6
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.

30608:LOC105862254
gene id: 30608:LOC105862254
uniprot id: A0A8B7F7N1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

30608:LOC105867756
gene id: 30608:LOC105867756
uniprot id: A0A8B7FW32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:AEBP1
gene id: 30608:AEBP1
uniprot id: A0A8B7ER74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

30608:ABCG4
gene id: 30608:ABCG4
uniprot id: A0A8B7GZ62
uniprot id: A0A8B7GZ64
uniprot id: A0A8B7X3N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

30608:LOC105863164
gene id: 30608:LOC105863164
uniprot id: A0A8B7FB96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:DIAPH2
gene id: 30608:DIAPH2
uniprot id: A0A8B7WZ19
names: Similarity
messages: Belongs to the formin homology family. Diaphanous subfamily.

30608:HOXC6
gene id: 30608:HOXC6
uniprot id: A0A8B7GBV4
uniprot id: A0A8C5Y1H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

30608:BLCAP
gene id: 30608:BLCAP
uniprot id: A0A8B7FNY9
names: Function
names: Similarity
messages: Belongs to the BLCAP family.
messages: May regulate cell proliferation and coordinate apoptosis and cell cycle progression via a novel mechanism independent of both p53/TP53 and NF-kappa-B.

30608:PTPRS
gene id: 30608:PTPRS
uniprot id: A0A8B7WVT9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

30608:FBN2
gene id: 30608:FBN2
uniprot id: A0A8B7EP30
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:SLC4A3
gene id: 30608:SLC4A3
uniprot id: A0A8B7ELP4
uniprot id: A0A8B7ELZ1
uniprot id: A0A8B7ENY7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:CHN1
gene id: 30608:CHN1
uniprot id: A0A8B7XA71
uniprot id: A0A8C5Y650
uniprot id: A0A8C5YA23
names: Function
messages: GTPase-activating protein for p21-rac.

30608:IL13RA1
gene id: 30608:IL13RA1
uniprot id: A0A8C5XVH1
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 5 subfamily.

30608:ZFHX3
gene id: 30608:ZFHX3
uniprot id: A0A8B7ERS9
uniprot id: A0A8B7ERT4
uniprot id: A0A8B7ETU5
uniprot id: A0A8C5UPJ5
names: Subcellular Location Annotation
messages: Nucleus

30608:NEMF
gene id: 30608:NEMF
uniprot id: A0A8B7X118
names: Similarity
messages: Belongs to the NEMF family.

30608:FAM122B
gene id: 30608:FAM122B
uniprot id: A0A8B7GCA9
uniprot id: A0A8B7GCB2
uniprot id: A0A8B7GCB3
uniprot id: A0A8B7GCB6
uniprot id: A0A8B7GCB7
uniprot id: A0A8B7GCU9
uniprot id: A0A8B7GCV5
uniprot id: A0A8B7GCX5
uniprot id: A0A8B7GDA0
uniprot id: A0A8B7GDA4
uniprot id: A0A8B7WYQ9
uniprot id: A0A8C5XCE7
names: Similarity
messages: Belongs to the FAM122 family.

30608:LOC105884627
gene id: 30608:LOC105884627
uniprot id: A0A8B7X721
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Cytoplasm
messages: Nucleus

30608:ALAD
gene id: 30608:ALAD
uniprot id: A0A8B7GMM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer; active form. Homohexamer; low activity form.

30608:MTMR2
gene id: 30608:MTMR2
uniprot id: A0A8B7EVN4
uniprot id: A0A8B7EVN6
uniprot id: A0A8B7EVN7
uniprot id: A0A8B7EVP2
uniprot id: A0A8B7EXN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

30608:RIOK1
gene id: 30608:RIOK1
uniprot id: A0A8B7FKA2
uniprot id: A0A8B7FKE6
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

30608:NAPRT
gene id: 30608:NAPRT
uniprot id: A0A8B7FII7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

30608:TDP1
gene id: 30608:TDP1
uniprot id: A0A8B7H069
uniprot id: A0A8B7H0D8
uniprot id: A0A8B7X268
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

30608:KARS
gene id: 30608:KARS
uniprot id: A0A8B7GWV0
uniprot id: A0A8B7GYK4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

30608:SLC43A1
gene id: 30608:SLC43A1
uniprot id: A0A8B7FB86
uniprot id: A0A8C5UPP6
names: Subcellular Location Annotation
messages: Membrane

30608:SLC46A3
gene id: 30608:SLC46A3
uniprot id: A0A8B7ERM7
uniprot id: A0A8C5V3Y6
names: Subcellular Location Annotation
messages: Membrane

30608:BCL2
gene id: 30608:BCL2
uniprot id: A0A8B7H1C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Nucleus membrane

30608:NFASC
gene id: 30608:NFASC
uniprot id: A0A8B7FZA3
uniprot id: A0A8B7FZA8
uniprot id: A0A8B7FZA9
uniprot id: A0A8B7FZF1
uniprot id: A0A8B7FZF4
uniprot id: A0A8B7FZF6
uniprot id: A0A8B7FZG5
uniprot id: A0A8B7FZG9
uniprot id: A0A8B7FZH0
uniprot id: A0A8B7FZH4
uniprot id: A0A8B7FZI8
uniprot id: A0A8B7FZK2
uniprot id: A0A8B7G0F4
uniprot id: A0A8B7G0F7
uniprot id: A0A8B7G0H0
uniprot id: A0A8B7G0K7
uniprot id: A0A8B7G0R1
uniprot id: A0A8C5YE17
uniprot id: A0A8C5YEA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

30608:LOC105858942
gene id: 30608:LOC105858942
uniprot id: A0A8B7ERT3
uniprot id: A0A8B7ETK1
uniprot id: A0A8C5XGL7
names: Similarity
messages: Belongs to the cytochrome b5 family.

30608:L3MBTL4
gene id: 30608:L3MBTL4
uniprot id: A0A8B7F168
uniprot id: A0A8B7F175
uniprot id: A0A8B7F176
uniprot id: A0A8B7F179
uniprot id: A0A8B7F180
uniprot id: A0A8B7F3J0
uniprot id: A0A8B7F3J2
uniprot id: A0A8B7WRJ7
uniprot id: A0A8B7WRM5
uniprot id: A0A8C5VEE6
names: Subcellular Location Annotation
messages: Nucleus

30608:GATB
gene id: 30608:GATB
uniprot id: A0A8C5UWB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

30608:SDHC
gene id: 30608:SDHC
uniprot id: A0A8B7GN93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: The heme is bound between the two transmembrane subunits.

30608:ACO2
gene id: 30608:ACO2
uniprot id: A0A8B7X8A6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Mitochondrion

30608:LOC105862591
gene id: 30608:LOC105862591
uniprot id: A0A8B7F8W5
uniprot id: A0A8B7F8Y1
uniprot id: A0A8B7F914
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:CCNA1
gene id: 30608:CCNA1
uniprot id: A0A8B7F6X4
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

30608:HTR2A
gene id: 30608:HTR2A
uniprot id: A0A8B7XF47
uniprot id: A0A8B7XFI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Presynapse
messages: Synapse
messages: Vesicle
messages: axon
messages: caveola
messages: dendrite

30608:LOC105859703
gene id: 30608:LOC105859703
uniprot id: A0A8B7EVB5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:WNK3
gene id: 30608:WNK3
uniprot id: A0A8B7HKV4
uniprot id: A0A8B7HKW4
uniprot id: A0A8B7HKX7
uniprot id: A0A8B7HNF0
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

30608:VPS11
gene id: 30608:VPS11
uniprot id: A0A8C5W3J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS11 family.
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: autophagosome
messages: clathrin-coated vesicle

30608:NARFL
gene id: 30608:NARFL
uniprot id: A0A8C5VY17
names: Similarity
messages: Belongs to the NARF family.

30608:CPA4
gene id: 30608:CPA4
uniprot id: A0A8C5UVU5
uniprot id: A0A8C6EHM3
names: Similarity
messages: Belongs to the peptidase M14 family.

30608:PLOD1
gene id: 30608:PLOD1
uniprot id: A0A8C5UU80
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

30608:MYO19
gene id: 30608:MYO19
uniprot id: A0A8B7H9B5
uniprot id: A0A8B7H9H5
uniprot id: A0A8B7H9Q7
uniprot id: A0A8B7HAG6
uniprot id: A0A8B7HCQ1
uniprot id: A0A8B7HDV2
uniprot id: A0A8B7WMD7
uniprot id: A0A8B7WNI3
uniprot id: A0A8C5VTB7
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PIAS1
gene id: 30608:PIAS1
uniprot id: A0A8B7GLD8
names: Similarity
messages: Belongs to the PIAS family.

30608:LOC109731319
gene id: 30608:LOC109731319
uniprot id: A0A8C5UU26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

30608:FKBP4
gene id: 30608:FKBP4
uniprot id: A0A8B7HM21
names: Subcellular Location Annotation
messages: Mitochondrion
messages: Nucleus
messages: cytoskeleton
messages: cytosol

30608:LOC105872435
gene id: 30608:LOC105872435
uniprot id: A0A8B7WMM5
uniprot id: A0A8C5Y3A2
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:SNUPN
gene id: 30608:SNUPN
uniprot id: A0A8B7E9T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snurportin family.
messages: Cytoplasm
messages: Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
messages: Nucleus

30608:OPALIN
gene id: 30608:OPALIN
uniprot id: A0A8B7GIJ9
uniprot id: A0A8B7GIK0
uniprot id: A0A8B7GIK4
uniprot id: A0A8B7GIV6
uniprot id: A0A8B7GIY4
uniprot id: A0A8B7GIY8
uniprot id: A0A8B7GJK0
uniprot id: A4PCE1
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Central nervous system-specific myelin protein that increase myelin genes expression during oligodendrocyte differentiation. Promotes oligodendrocyte terminal differentiation.
messages: Membrane

30608:ACTR10
gene id: 30608:ACTR10
uniprot id: A0A8B7X1Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: cytoskeleton

30608:KCNA10
gene id: 30608:KCNA10
uniprot id: A0A8B7FF93
names: Subcellular Location Annotation
messages: Membrane

30608:ELAC1
gene id: 30608:ELAC1
uniprot id: A0A8B7GQC1
names: Subunit
messages: Homodimer.

30608:LRP12
gene id: 30608:LRP12
uniprot id: A0A8B7HPI7
uniprot id: A0A8B7HPJ3
uniprot id: A0A8B7HR79
uniprot id: A0A8B7HRY6
uniprot id: A0A8C5Y6D6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ABCG2
gene id: 30608:ABCG2
uniprot id: A0A8B7WXL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion membrane

30608:ARMCX1
gene id: 30608:ARMCX1
uniprot id: A0A8B7WZG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eutherian X-chromosome-specific Armcx family.
messages: Membrane

30608:PRDM6
gene id: 30608:PRDM6
uniprot id: A0A8C5Y1B4
names: Subcellular Location Annotation
messages: Nucleus

30608:RPL3L
gene id: 30608:RPL3L
uniprot id: A0A8B7EWQ7
uniprot id: A0A8C5XPJ5
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

30608:LOC105883398
gene id: 30608:LOC105883398
uniprot id: A0A8B7HX55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105858725
gene id: 30608:LOC105858725
uniprot id: A0A8B7ESR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

30608:ACER2
gene id: 30608:ACER2
uniprot id: A0A8B7GQ65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:GRIK3
gene id: 30608:GRIK3
uniprot id: A0A8B7HEH4
uniprot id: A0A8C5XEU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

30608:GRIA1
gene id: 30608:GRIA1
uniprot id: A0A8B7FI54
uniprot id: A0A8B7FIA9
uniprot id: A0A8B7FJJ7
uniprot id: A0A8B7FJK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

30608:KPNB1
gene id: 30608:KPNB1
uniprot id: A0A8C5XDS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

30608:GTPBP3
gene id: 30608:GTPBP3
uniprot id: A0A8B7WZ63
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.

30608:LOC105864714
gene id: 30608:LOC105864714
uniprot id: A0A8B7FI27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:EVPL
gene id: 30608:EVPL
uniprot id: A0A8B7HBX2
names: Subcellular Location Annotation
messages: cytoskeleton

30608:FARS2
gene id: 30608:FARS2
uniprot id: A0A8B7EF88
uniprot id: A0A8B7EG10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

30608:KIAA1191
gene id: 30608:KIAA1191
uniprot id: A0A8B7HI66
uniprot id: A0A8B7HJ48
uniprot id: A0A8B7WXL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P33MONOX family.
messages: Cytoplasm
messages: Interacts with NELFB, NOL12 and PRNP.
messages: Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth.

30608:AURKB
gene id: 30608:AURKB
uniprot id: A0A8B7H3W7
uniprot id: A0A8B7H3Y2
uniprot id: A0A8B7H3Z2
uniprot id: A0A8B7WMR2
uniprot id: A0A8C5VMP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: centromere

30608:CNNM1
gene id: 30608:CNNM1
uniprot id: A0A8B7GKS9
uniprot id: A0A8C5UXD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

30608:MMP26
gene id: 30608:MMP26
uniprot id: A0A8B7HX20
names: Similarity
messages: Belongs to the peptidase M10A family.

30608:DCTN1
gene id: 30608:DCTN1
uniprot id: A0A8B7I0G3
uniprot id: A0A8B7I0G8
uniprot id: A0A8B7I0H3
uniprot id: A0A8B7I0H8
uniprot id: A0A8B7I0I6
uniprot id: A0A8B7I2L1
uniprot id: A0A8B7I2L6
uniprot id: A0A8B7I397
uniprot id: A0A8B7I3A2
uniprot id: A0A8B7X265
uniprot id: A0A8B7X269
uniprot id: A0A8B7X2Q6
uniprot id: A0A8B7X3H9
uniprot id: A0A8B7X3X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin 150 kDa subunit family.
messages: Cytoplasm
messages: cell cortex
messages: cytoskeleton

30608:LOC105864878
gene id: 30608:LOC105864878
uniprot id: A0A8B7FIV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:CFAP97
gene id: 30608:CFAP97
uniprot id: A0A8B7HTJ4
names: Similarity
messages: Belongs to the CFAP97 family.

30608:ABCG8
gene id: 30608:ABCG8
uniprot id: A0A8B7FSQ0
uniprot id: A0A8B7FT36
uniprot id: A0A8B7X8V0
uniprot id: A0A8B7X9J7
uniprot id: A0A8C5UYT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

30608:LOC109729691
gene id: 30608:LOC109729691
uniprot id: A0A8B7WQH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

30608:LOC105861263
gene id: 30608:LOC105861263
uniprot id: A0A8B7F2I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:FXR2
gene id: 30608:FXR2
uniprot id: A0A8C5V2R3
names: Similarity
messages: Belongs to the FMR1 family.

30608:REM1
gene id: 30608:REM1
uniprot id: A0A8B7FPF3
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

30608:HDAC5
gene id: 30608:HDAC5
uniprot id: A0A8B7HVM1
uniprot id: A0A8B7HVN8
uniprot id: A0A8B7HXT2
uniprot id: A0A8B7HXX7
uniprot id: A0A8B7WNA7
uniprot id: A0A8C5Y7Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

30608:NAIF1
gene id: 30608:NAIF1
uniprot id: A0A8B7GVK0
uniprot id: A0A8B7GVP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

30608:BRMS1
gene id: 30608:BRMS1
uniprot id: A0A8B7FUN2
uniprot id: A0A8B7FVJ6
uniprot id: A0A8B7X496
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105872827
gene id: 30608:LOC105872827
uniprot id: A0A8B7GI99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

30608:COG2
gene id: 30608:COG2
uniprot id: A0A8B7EGH7
uniprot id: A0A8B7EIY1
names: Similarity
messages: Belongs to the COG2 family.

30608:LOC105885541
gene id: 30608:LOC105885541
uniprot id: A0A8B7I533
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NASP
gene id: 30608:NASP
uniprot id: A0A8B7H502
uniprot id: A0A8B7H503
uniprot id: A0A8B7H7A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

30608:FAM210A
gene id: 30608:FAM210A
uniprot id: A0A8B7F363
names: Similarity
messages: Belongs to the FAM210 family.

30608:AHSA2
gene id: 30608:AHSA2
uniprot id: A0A8B7GCH0
uniprot id: A0A8B7GCH1
uniprot id: A0A8B7GCH6
uniprot id: A0A8B7GD15
names: Similarity
messages: Belongs to the AHA1 family.

30608:B4GALT7
gene id: 30608:B4GALT7
uniprot id: A0A8B7HXB6
uniprot id: A0A8B7HXC4
uniprot id: A0A8B7HZF4
uniprot id: A0A8B7HZX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

30608:C8A
gene id: 30608:C8A
uniprot id: A0A8C5UKU7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

30608:PPP2R2D
gene id: 30608:PPP2R2D
uniprot id: A0A8B7HHZ6
uniprot id: A0A8B7HI19
uniprot id: A0A8B7HIW7
uniprot id: A0A8B7WMA3
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

30608:BHMT
gene id: 30608:BHMT
uniprot id: A0A8B7GHD2
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

30608:WBP4
gene id: 30608:WBP4
uniprot id: A0A8C5Y399
names: Subcellular Location Annotation
messages: Nucleus

30608:DESI2
gene id: 30608:DESI2
uniprot id: A0A8B7FFP4
names: Similarity
messages: Belongs to the DeSI family.

30608:ENTPD1
gene id: 30608:ENTPD1
uniprot id: A0A8B7GHY1
uniprot id: A0A8B7GI18
uniprot id: A0A8B7GIA6
uniprot id: A0A8B7GIL5
uniprot id: A0A8B7GIX2
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

30608:HEBP2
gene id: 30608:HEBP2
uniprot id: A0A8B7X6V6
names: Similarity
messages: Belongs to the HEBP family.

30608:SEMA3B
gene id: 30608:SEMA3B
uniprot id: A0A8B7WKY1
uniprot id: A0A8B7WL20
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:RPS6
gene id: 30608:RPS6
uniprot id: A0A8B7GPT1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

30608:SLC19A3
gene id: 30608:SLC19A3
uniprot id: A0A8B7FA38
uniprot id: A0A8B7FA49
uniprot id: A0A8C5VUA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

30608:PPP1R21
gene id: 30608:PPP1R21
uniprot id: A0A8B7FPY9
uniprot id: A0A8B7FQ07
uniprot id: A0A8B7FQ16
uniprot id: A0A8B7FQB4
uniprot id: A0A8B7FR21
uniprot id: A0A8B7X8T6
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

30608:LOC105871425
gene id: 30608:LOC105871425
uniprot id: A0A8B7X6B8
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

30608:RPAP1
gene id: 30608:RPAP1
uniprot id: A0A8B7GGM9
uniprot id: A0A8B7GHI0
names: Similarity
messages: Belongs to the RPAP1 family.

30608:SLC6A4
gene id: 30608:SLC6A4
uniprot id: A0A8B7EMV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Membrane
messages: Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
messages: Synapse
messages: focal adhesion

30608:PEX14
gene id: 30608:PEX14
uniprot id: A0A8B7I7E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the peroxisomal translocation machinery.
messages: Peroxisome membrane

30608:RYR2
gene id: 30608:RYR2
uniprot id: A0A8B7WPK9
uniprot id: A0A8B7WPL1
uniprot id: A0A8B7WPL6
uniprot id: A0A8B7WPL7
uniprot id: A0A8B7WPQ5
uniprot id: A0A8B7WQY9
uniprot id: A0A8B7WQZ6
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

30608:CUEDC2
gene id: 30608:CUEDC2
uniprot id: A0A8B7GQA3
uniprot id: A0A8B7GQN6
uniprot id: A0A8B7GRS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUEDC2 family.
messages: Cytoplasm
messages: Nucleus

30608:FOXE1
gene id: 30608:FOXE1
uniprot id: A0A8B7GNV2
names: Subcellular Location Annotation
messages: Nucleus

30608:TIGD4
gene id: 30608:TIGD4
uniprot id: A0A8B7HN45
names: Subcellular Location Annotation
messages: Nucleus

30608:SLC19A1
gene id: 30608:SLC19A1
uniprot id: A0A8B7WYE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Cell membrane
messages: Transporter that mediates the import of reduced folates.

30608:OXR1
gene id: 30608:OXR1
uniprot id: A0A8B7HPH7
uniprot id: A0A8B7HPH9
uniprot id: A0A8B7HPI3
uniprot id: A0A8B7HPI6
uniprot id: A0A8B7HPJ1
uniprot id: A0A8B7HR70
uniprot id: A0A8B7HRX3
uniprot id: A0A8C5XI10
names: Similarity
messages: Belongs to the OXR1 family.

30608:INHBB
gene id: 30608:INHBB
uniprot id: A0A8C5Y2M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

30608:GLE1
gene id: 30608:GLE1
uniprot id: A0A8B7XBD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
messages: nuclear pore complex

30608:SPTB
gene id: 30608:SPTB
uniprot id: A0A8C5V127
names: Similarity
messages: Belongs to the spectrin family.

30608:NKX6-1
gene id: 30608:NKX6-1
uniprot id: A0A8B7GSZ2
names: Subcellular Location Annotation
messages: Nucleus

30608:TRAPPC2
gene id: 30608:TRAPPC2
uniprot id: A0A8C5XGW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

30608:ADGRG5
gene id: 30608:ADGRG5
uniprot id: A0A8B7WS70
names: Subcellular Location Annotation
messages: Membrane

30608:DYSF
gene id: 30608:DYSF
uniprot id: A0A8B7FBI5
uniprot id: A0A8B7FBJ1
uniprot id: A0A8B7FBJ2
uniprot id: A0A8B7FBJ6
uniprot id: A0A8B7FBK2
uniprot id: A0A8B7FBK3
uniprot id: A0A8B7FBK4
uniprot id: A0A8B7FBK7
uniprot id: A0A8B7FBK8
uniprot id: A0A8B7FBL0
uniprot id: A0A8B7FBL3
uniprot id: A0A8B7FBL5
uniprot id: A0A8B7FBP4
uniprot id: A0A8B7FBQ8
uniprot id: A0A8B7FBR5
uniprot id: A0A8B7FBS1
uniprot id: A0A8B7FC78
uniprot id: A0A8B7FC84
uniprot id: A0A8B7FC89
uniprot id: A0A8B7FC95
uniprot id: A0A8C5VAV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferlin family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

30608:FAM69A
gene id: 30608:FAM69A
uniprot id: A0A8B7I621
uniprot id: A0A8B7I9A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

30608:PKDREJ
gene id: 30608:PKDREJ
uniprot id: A0A8B7X6L1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:PLPP2
gene id: 30608:PLPP2
uniprot id: A0A8B7F0N5
uniprot id: A0A8C5W9F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

30608:AAR2
gene id: 30608:AAR2
uniprot id: A0A8C5UQ23
names: Function
names: Similarity
messages: Belongs to the AAR2 family.
messages: Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.

30608:GPER1
gene id: 30608:GPER1
uniprot id: A0A8B7WPT1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:COG4
gene id: 30608:COG4
uniprot id: A0A8B7GWM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG4 family.
messages: Golgi apparatus membrane

30608:GDF11
gene id: 30608:GDF11
uniprot id: A0A8B7FIQ2
names: Similarity
messages: Belongs to the TGF-beta family.

30608:AP2B1
gene id: 30608:AP2B1
uniprot id: A0A8B7HWD4
uniprot id: A0A8B7HWN7
uniprot id: A0A8B7HXC3
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

30608:PSMB1
gene id: 30608:PSMB1
uniprot id: A0A8C5Y4V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

30608:LOC105878806
gene id: 30608:LOC105878806
uniprot id: A0A8B7XE05
uniprot id: A0A8B7XE07
uniprot id: A0A8B7XE11
uniprot id: A0A8B7XFD1
uniprot id: A0A8B7XFS7
uniprot id: A0A8B7XGB2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:P2RX3
gene id: 30608:P2RX3
uniprot id: A0A8B7FB75
uniprot id: A0A8B7FBV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

30608:POLG
gene id: 30608:POLG
uniprot id: A0A8B7I154
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: Heterotrimer composed of a catalytic subunit and a homodimer of accessory subunits.
messages: Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA.
messages: mitochondrion nucleoid

30608:UNC45A
gene id: 30608:UNC45A
uniprot id: A0A8B7G979
uniprot id: A0A8C5VNG0
names: Subcellular Location Annotation
messages: perinuclear region

30608:OVCH2
gene id: 30608:OVCH2
uniprot id: A0A8B7EWG8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:YWHAG
gene id: 30608:YWHAG
uniprot id: A0A8C5VYM3
names: Similarity
messages: Belongs to the 14-3-3 family.

30608:LOC105866209
gene id: 30608:LOC105866209
uniprot id: A0A8B7FPR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

30608:TM6SF2
gene id: 30608:TM6SF2
uniprot id: A0A8B7WVL6
names: Subcellular Location Annotation
messages: Membrane

30608:GPR101
gene id: 30608:GPR101
uniprot id: A0A8B7HKD2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:PINLYP
gene id: 30608:PINLYP
uniprot id: A0A8C5Y782
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNF-like-inhibitor family.
messages: Secreted

30608:TBL3
gene id: 30608:TBL3
uniprot id: A0A8C5W914
names: Subcellular Location Annotation
messages: nucleolus

30608:LOC105862654
gene id: 30608:LOC105862654
uniprot id: A0A8C5YHT0
names: Similarity
messages: Belongs to the PRR23 family.

30608:LOC105879402
gene id: 30608:LOC105879402
uniprot id: A0A8B7HDR9
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:IGF2R
gene id: 30608:IGF2R
uniprot id: A0A8B7FZN5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:NFU1
gene id: 30608:NFU1
uniprot id: A0A8B7FCJ6
names: Similarity
messages: Belongs to the NifU family.

30608:SAMD4A
gene id: 30608:SAMD4A
uniprot id: A0A8B7X1N0
uniprot id: A0A8C5XYC9
uniprot id: A0A8C5Y540
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

30608:OTX2
gene id: 30608:OTX2
uniprot id: A0A8C5XXY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

30608:COG3
gene id: 30608:COG3
uniprot id: A0A8B7HM45
names: Function
names: Similarity
messages: Belongs to the COG3 family.
messages: Involved in ER-Golgi transport.

30608:ZNF446
gene id: 30608:ZNF446
uniprot id: A0A8B7FHK1
uniprot id: A0A8B7FIM8
names: Subcellular Location Annotation
messages: Nucleus

30608:FABP6
gene id: 30608:FABP6
uniprot id: A0A8C5XBJ5
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

30608:LAMTOR2
gene id: 30608:LAMTOR2
uniprot id: A0A8B7GJW9
uniprot id: A0A8C5XBA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAMAD family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

30608:ACSM5
gene id: 30608:ACSM5
uniprot id: A0A8B7EBG7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

30608:GPR3
gene id: 30608:GPR3
uniprot id: A0A8B7FCZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LACC1
gene id: 30608:LACC1
uniprot id: A0A8C5XWG1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

30608:CCDC22
gene id: 30608:CCDC22
uniprot id: A0A8B7EGF9
uniprot id: A0A8B7EGV2
names: Similarity
messages: Belongs to the CCDC22 family.

30608:DZIP3
gene id: 30608:DZIP3
uniprot id: A0A8B7H7Y3
uniprot id: A0A8B7HAJ0
names: Subcellular Location Annotation
messages: Cytoplasm

30608:CA12
gene id: 30608:CA12
uniprot id: A0A8B7FXI6
uniprot id: A0A8B7FYH7
uniprot id: A0A8B7FYL3
uniprot id: A0A8C5W806
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

30608:LIN7A
gene id: 30608:LIN7A
uniprot id: A0A8B7X703
uniprot id: A0A8C5VR01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the lin-7 family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.
messages: Postsynaptic density membrane
messages: tight junction

30608:AKAP8L
gene id: 30608:AKAP8L
uniprot id: A0A8B7FWM6
uniprot id: A0A8B7FWN0
names: Similarity
messages: Belongs to the AKAP95 family.

30608:LOC105864876
gene id: 30608:LOC105864876
uniprot id: A0A8B7WU25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

30608:LOC105874297
gene id: 30608:LOC105874297
uniprot id: A0A8B7GS07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:STK10
gene id: 30608:STK10
uniprot id: A0A8C5XBT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Cell membrane

30608:ALG13
gene id: 30608:ALG13
uniprot id: A0A8B7WYE8
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

30608:TMEM38B
gene id: 30608:TMEM38B
uniprot id: A0A8C5USY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

30608:GMNN
gene id: 30608:GMNN
uniprot id: A0A8B7EPH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the geminin family.
messages: Nucleus

30608:KCNK1
gene id: 30608:KCNK1
uniprot id: A0A8C5Y002
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

30608:NDUFS4
gene id: 30608:NDUFS4
uniprot id: A0A8B7FSZ1
uniprot id: A0A8B7FTX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Mitochondrion inner membrane

30608:CDH9
gene id: 30608:CDH9
uniprot id: A0A8B7GDA7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

30608:LOC105868771
gene id: 30608:LOC105868771
uniprot id: A0A8B7WV27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

30608:LOC105884139
gene id: 30608:LOC105884139
uniprot id: A0A8B7X2X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NR2C1
gene id: 30608:NR2C1
uniprot id: A0A8C5W9N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

30608:GEM
gene id: 30608:GEM
uniprot id: A0A8B7GXI6
uniprot id: A0A8B7GXJ2
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

30608:TPD52L3
gene id: 30608:TPD52L3
uniprot id: A0A8B7EGU2
names: Similarity
messages: Belongs to the TPD52 family.

30608:MMP7
gene id: 30608:MMP7
uniprot id: A0A8B7GRY0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Binds 2 calcium ions per subunit.

30608:ERLEC1
gene id: 30608:ERLEC1
uniprot id: A0A8B7H9A3
uniprot id: A0A8C5VNV4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum lumen

30608:PKD1
gene id: 30608:PKD1
uniprot id: A0A8B7EUH9
uniprot id: A0A8B7EUI7
uniprot id: A0A8B7EWG9
uniprot id: A0A8B7EWH5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:TRPM5
gene id: 30608:TRPM5
uniprot id: A0A8B7FW49
names: Subcellular Location Annotation
messages: Membrane

30608:PAX7
gene id: 30608:PAX7
uniprot id: A0A8B7WPN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

30608:KAT2A
gene id: 30608:KAT2A
uniprot id: A0A8C5W337
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: centrosome

30608:LOC109730588
gene id: 30608:LOC109730588
uniprot id: A0A8B7X241
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

30608:NME4
gene id: 30608:NME4
uniprot id: A0A8B7EFH4
uniprot id: A0A8B7EG05
uniprot id: A0A8C5XW53
names: Similarity
messages: Belongs to the NDK family.

30608:LOC105868766
gene id: 30608:LOC105868766
uniprot id: A0A8B7WP52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AGK family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

30608:TBCA
gene id: 30608:TBCA
uniprot id: A0A8C5Y8X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
messages: cytoskeleton

30608:NIPA1
gene id: 30608:NIPA1
uniprot id: A0A8C5VLY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

30608:CLIC6
gene id: 30608:CLIC6
uniprot id: A0A8B7HNX2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cell membrane
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

30608:ADGRD2
gene id: 30608:ADGRD2
uniprot id: A0A8B7XDB9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:ZNF711
gene id: 30608:ZNF711
uniprot id: A0A8B7I406
uniprot id: A0A8B7I426
uniprot id: A0A8B7I732
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105861295
gene id: 30608:LOC105861295
uniprot id: A0A8B7F445
names: Subcellular Location Annotation
messages: Membrane

30608:NSUN2
gene id: 30608:NSUN2
uniprot id: A0A8B7EWJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: extracellular exosome

30608:DNPEP
gene id: 30608:DNPEP
uniprot id: A0A8B7ELE1
uniprot id: A0A8B7EMS4
uniprot id: A0A8B7ENP2
names: Similarity
names: Subunit
messages: Belongs to the peptidase M18 family.
messages: Tetrahedron-shaped homododecamer built from six homodimers.

30608:SLC25A39
gene id: 30608:SLC25A39
uniprot id: A0A8B7HVS0
uniprot id: A0A8B7HXW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis.
messages: Mitochondrion inner membrane

30608:LOC109730837
gene id: 30608:LOC109730837
uniprot id: A0A8B7X795
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

30608:TRDMT1
gene id: 30608:TRDMT1
uniprot id: A0A8B7FKP6
uniprot id: A0A8B7FKQ2
uniprot id: A0A8B7FM05
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

30608:NKX2-3
gene id: 30608:NKX2-3
uniprot id: A0A8B7GKX8
names: Subcellular Location Annotation
messages: Nucleus

30608:EIF3A
gene id: 30608:EIF3A
uniprot id: A0A8B7EIW6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3L and EIF3K. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with EIF4G1. Also interacts with KRT7 and PIWIL2.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.

30608:SERPINF1
gene id: 30608:SERPINF1
uniprot id: A0A8B7EN52
names: Similarity
messages: Belongs to the serpin family.

30608:ASB15
gene id: 30608:ASB15
uniprot id: A0A8B7XC02
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

30608:LOC105869130
gene id: 30608:LOC105869130
uniprot id: A0A8B7WU30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

30608:CUBN
gene id: 30608:CUBN
uniprot id: A0A8B7FKU9
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

30608:SKOR2
gene id: 30608:SKOR2
uniprot id: A0A8B7WRK9
names: Similarity
messages: Belongs to the SKI family.

30608:CACNA2D2
gene id: 30608:CACNA2D2
uniprot id: A0A8B7GTV2
uniprot id: A0A8B7GTV4
uniprot id: A0A8B7GU03
uniprot id: A0A8B7GU29
uniprot id: A0A8B7WKY0
uniprot id: A0A8B7WKY6
uniprot id: A0A8B7WL01
uniprot id: A0A8B7WL06
uniprot id: A0A8B7WL25
uniprot id: A0A8B7WLR7
uniprot id: A0A8B7WLS3
uniprot id: A0A8C5Y6R1
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

30608:FCER1G
gene id: 30608:FCER1G
uniprot id: A0A8B7GMG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Membrane

30608:CUTA
gene id: 30608:CUTA
uniprot id: A0A8B7I930
uniprot id: A0A8C5VZJ2
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

30608:RPRD1A
gene id: 30608:RPRD1A
uniprot id: A0A8B7ER54
uniprot id: A0A8B7ER76
uniprot id: A0A8C5XRY9
names: Function
names: Similarity
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD.

30608:LOC105862471
gene id: 30608:LOC105862471
uniprot id: A0A8B7F8E0
names: Similarity
messages: Belongs to the peptidase C14A family.

30608:HMCN2
gene id: 30608:HMCN2
uniprot id: A0A8B7FNV9
uniprot id: A0A8B7XBF3
uniprot id: A0A8B7XCC5
uniprot id: A0A8B7XD60
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:CREM
gene id: 30608:CREM
uniprot id: A0A8B7GF12
names: Subcellular Location Annotation
messages: Nucleus

30608:CXXC4
gene id: 30608:CXXC4
uniprot id: A0A8B7HEW3
uniprot id: A0A8B7WXD9
uniprot id: A0A8C5XZY7
names: Subcellular Location Annotation
messages: Cytoplasm

30608:CCND1
gene id: 30608:CCND1
uniprot id: A0A8C5VUL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Nucleus

30608:LOC105860069
gene id: 30608:LOC105860069
uniprot id: A0A8B7EX54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 54 family.
messages: Golgi apparatus membrane

30608:ST14
gene id: 30608:ST14
uniprot id: A0A8B7X3R7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S1 family.
messages: Degrades extracellular matrix.
messages: Interacts with CDCP1. May interact with TMEFF1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:MS4A5
gene id: 30608:MS4A5
uniprot id: A0A8C5XEG8
names: Similarity
messages: Belongs to the MS4A family.

30608:UBE2I
gene id: 30608:UBE2I
uniprot id: A0A8B7WP28
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:HOXD4
gene id: 30608:HOXD4
uniprot id: A0A8B7FK19
uniprot id: A0A8B7FL79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

30608:GCNT1
gene id: 30608:GCNT1
uniprot id: A0A8B7XBB4
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

30608:EDC4
gene id: 30608:EDC4
uniprot id: A0A8B7ES14
uniprot id: A0A8B7ES15
uniprot id: A0A8B7ES22
uniprot id: A0A8B7EU37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EDC4 family.
messages: P-body

30608:PLG
gene id: 30608:PLG
uniprot id: A0A8B7FZR6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Converted into plasmin by plasminogen activators, both plasminogen and its activator being bound to fibrin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.
messages: Secreted

30608:LOC105873310
gene id: 30608:LOC105873310
uniprot id: A0A8B7GL25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105880290
gene id: 30608:LOC105880290
uniprot id: A0A8B7HHG4
names: Similarity
messages: Belongs to the cytochrome b5 family.

30608:BAX
gene id: 30608:BAX
uniprot id: A0A8B7FM20
uniprot id: A0A8B7WV46
names: Similarity
messages: Belongs to the Bcl-2 family.

30608:LOC105873909
gene id: 30608:LOC105873909
uniprot id: A0A8C6ELI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.
messages: Peroxisome

30608:GCNT4
gene id: 30608:GCNT4
uniprot id: A0A8C5V940
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

30608:TMEM183A
gene id: 30608:TMEM183A
uniprot id: A0A8B7EWX8
uniprot id: A0A8B7EYY5
uniprot id: A0A8C5YD92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM183 family.
messages: Membrane

30608:PLK3
gene id: 30608:PLK3
uniprot id: A0A8B7H752
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

30608:TMCO4
gene id: 30608:TMCO4
uniprot id: A0A8B7HY27
names: Similarity
messages: Belongs to the TMCO4 family.

30608:PDP1
gene id: 30608:PDP1
uniprot id: A0A8B7GXI3
uniprot id: A0A8B7GXJ5
uniprot id: A0A8B7XBW1
uniprot id: A0A8C5V7J9
names: Similarity
messages: Belongs to the PP2C family.

30608:MTAP
gene id: 30608:MTAP
uniprot id: A0A8B7GQD6
uniprot id: A0A8C5VKH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

30608:PDGFC
gene id: 30608:PDGFC
uniprot id: A0A8B7HMY5
uniprot id: A0A8B7HPH0
uniprot id: A0A8B7HQF1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:GABARAP
gene id: 30608:GABARAP
uniprot id: A0A8C5XM83
names: Similarity
messages: Belongs to the ATG8 family.

30608:MACF1
gene id: 30608:MACF1
uniprot id: A0A8B7HEA5
uniprot id: A0A8B7HEA6
uniprot id: A0A8B7HEB0
uniprot id: A0A8B7HEB2
uniprot id: A0A8B7HEB7
uniprot id: A0A8B7HEB9
uniprot id: A0A8B7HEC2
uniprot id: A0A8B7HEC5
uniprot id: A0A8B7HEC6
uniprot id: A0A8B7HEC7
uniprot id: A0A8B7HED0
uniprot id: A0A8B7HED1
uniprot id: A0A8B7HED3
uniprot id: A0A8B7HED7
uniprot id: A0A8B7HEE2
uniprot id: A0A8B7HEE8
uniprot id: A0A8B7HEN3
uniprot id: A0A8B7HEP0
uniprot id: A0A8B7HEP8
uniprot id: A0A8B7HEQ4
uniprot id: A0A8B7HER1
uniprot id: A0A8B7HGY4
uniprot id: A0A8B7HGZ0
uniprot id: A0A8B7HGZ5
uniprot id: A0A8B7HH04
uniprot id: A0A8B7HH09
uniprot id: A0A8B7WKJ3
uniprot id: A0A8B7WKJ7
uniprot id: A0A8B7WKL2
uniprot id: A0A8B7WKL4
uniprot id: A0A8B7WKM6
uniprot id: A0A8B7WKN2
uniprot id: A0A8B7WKN7
uniprot id: A0A8B7WKP6
uniprot id: A0A8B7WL95
names: Subcellular Location Annotation
messages: cytoskeleton

30608:MRPS26
gene id: 30608:MRPS26
uniprot id: A0A8B7FNV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS26 family.
messages: Mitochondrion

30608:ACVR1C
gene id: 30608:ACVR1C
uniprot id: A0A8C5XSY5
uniprot id: A0A8C5YC80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

30608:EIF4E3
gene id: 30608:EIF4E3
uniprot id: A0A8B7WY94
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

30608:TRAPPC4
gene id: 30608:TRAPPC4
uniprot id: A0A8C5Y3H4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

30608:MTG1
gene id: 30608:MTG1
uniprot id: A0A8B7F3C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Mitochondrion inner membrane
messages: Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays mitochondrial GTPase activity.

30608:POLR2I
gene id: 30608:POLR2I
uniprot id: A0A8B7H2H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

30608:LOC105866529
gene id: 30608:LOC105866529
uniprot id: A0A8B7FR00
names: Subcellular Location Annotation
messages: Membrane

30608:ADGRG4
gene id: 30608:ADGRG4
uniprot id: A0A8B7X0G3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:PRPF38A
gene id: 30608:PRPF38A
uniprot id: A0A8B7H5K4
uniprot id: A0A8C5XEA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRP38 family.
messages: Component of the spliceosome B complex.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: Nucleus

30608:RFX2
gene id: 30608:RFX2
uniprot id: A0A8B7G4L0
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105867901
gene id: 30608:LOC105867901
uniprot id: A0A8B7FWR1
names: Subcellular Location Annotation
messages: Membrane

30608:SLC14A2
gene id: 30608:SLC14A2
uniprot id: A0A8B7I7N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

30608:TMEM192
gene id: 30608:TMEM192
uniprot id: A0A8B7GRY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

30608:LOC105884148
gene id: 30608:LOC105884148
uniprot id: A0A8B7I186
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105865918
gene id: 30608:LOC105865918
uniprot id: A0A8B7G9Y0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

30608:AGPAT2
gene id: 30608:AGPAT2
uniprot id: A0A8B7XDQ8
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

30608:PALMD
gene id: 30608:PALMD
uniprot id: A0A8B7F849
names: Similarity
messages: Belongs to the paralemmin family.

30608:LOC105858286
gene id: 30608:LOC105858286
uniprot id: A0A8B7EP53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

30608:CCKAR
gene id: 30608:CCKAR
uniprot id: A0A8B7FMM8
uniprot id: A0A8B7FN07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

30608:TMEM38A
gene id: 30608:TMEM38A
uniprot id: A0A8B7FWW5
uniprot id: A0A8B7FXP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

30608:RSPO4
gene id: 30608:RSPO4
uniprot id: A0A8B7FMX2
uniprot id: A0A8C5YDM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-spondin family.
messages: Secreted

30608:ADGRF4
gene id: 30608:ADGRF4
uniprot id: A0A8B7EXX7
names: Subcellular Location Annotation
messages: Membrane

30608:ITIH4
gene id: 30608:ITIH4
uniprot id: A0A8B7GUB5
uniprot id: A0A8B7GUG3
uniprot id: A0A8B7GW54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

30608:KDM5C
gene id: 30608:KDM5C
uniprot id: A0A8B7F2F6
uniprot id: A0A8B7F2F7
uniprot id: A0A8B7F2F9
uniprot id: A0A8B7F2G2
uniprot id: A0A8B7F3R9
uniprot id: A0A8B7F424
uniprot id: A0A8C5W8D5
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

30608:RTN2
gene id: 30608:RTN2
uniprot id: A0A8B7G5C2
uniprot id: A0A8C6EIC9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:RCAN3
gene id: 30608:RCAN3
uniprot id: A0A8C5YA38
names: Similarity
messages: Belongs to the RCAN family.

30608:LOC105883495
gene id: 30608:LOC105883495
uniprot id: A0A8B7HVF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:EIF5A2
gene id: 30608:EIF5A2
uniprot id: A0A8C5YHL0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

30608:DOC2B
gene id: 30608:DOC2B
uniprot id: A0A8B7EPR9
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105856008
gene id: 30608:LOC105856008
uniprot id: A0A8B7EF11
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

30608:LOC105885006
gene id: 30608:LOC105885006
uniprot id: A0A8B7I2P1
uniprot id: A0A8B7I5N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCO1/2 family.
messages: Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.
messages: Homodimer.
messages: Mitochondrion inner membrane

30608:LOC105883343
gene id: 30608:LOC105883343
uniprot id: A0A8B7HUV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SEPT10
gene id: 30608:SEPT10
uniprot id: A0A8B7EHH8
uniprot id: A0A8B7X2Y4
uniprot id: A0A8B7X459
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

30608:ATE1
gene id: 30608:ATE1
uniprot id: A0A8B7HHI4
uniprot id: A0A8B7HHI5
uniprot id: A0A8B7HHK9
uniprot id: A0A8B7HID5
uniprot id: A0A8B7HK52
uniprot id: A0A8B7WM02
uniprot id: A0A8B7WM10
uniprot id: A0A8B7WM35
uniprot id: A0A8B7WM60
uniprot id: A0A8B7WN39
names: Function
names: Similarity
messages: Belongs to the R-transferase family.
messages: Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.

30608:LOC105860027
gene id: 30608:LOC105860027
uniprot id: A0A8B7EWV4
uniprot id: A0A8B7WWY1
uniprot id: A0A8B7WXQ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:CCR9
gene id: 30608:CCR9
uniprot id: A0A8B7GRJ0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:CHRNA10
gene id: 30608:CHRNA10
uniprot id: A0A8B7EYH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:RING1
gene id: 30608:RING1
uniprot id: A0A8B7I750
names: Function
names: Subcellular Location Annotation
messages: Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. Compared to RNF2/RING2, it does not have the main E3 ubiquitin ligase activity on histone H2A, and it may rather act as a modulator of RNF2/RING2 activity.
messages: Nucleus speckle

30608:LOC105862176
gene id: 30608:LOC105862176
uniprot id: A0A8B7F792
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PSMD4
gene id: 30608:PSMD4
uniprot id: A0A8B7GJN2
uniprot id: A0A8B7GKF4
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

30608:LOC105883466
gene id: 30608:LOC105883466
uniprot id: A0A8B7HVC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:OCLN
gene id: 30608:OCLN
uniprot id: A0A8B7HLX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

30608:CHRNA6
gene id: 30608:CHRNA6
uniprot id: A0A8B7WUA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:HSPA9
gene id: 30608:HSPA9
uniprot id: A0A8C5XID7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

30608:TRAF5
gene id: 30608:TRAF5
uniprot id: A0A8B7WX22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

30608:CLPP
gene id: 30608:CLPP
uniprot id: A0A8B7G4M4
names: Similarity
messages: Belongs to the peptidase S14 family.

30608:LOC105884140
gene id: 30608:LOC105884140
uniprot id: A0A8B7HYI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TRAK1
gene id: 30608:TRAK1
uniprot id: A0A8B7GR31
uniprot id: A0A8B7GR36
uniprot id: A0A8B7GR42
uniprot id: A0A8B7GRC1
uniprot id: A0A8B7GRG6
uniprot id: A0A8B7GSQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

30608:HIBADH
gene id: 30608:HIBADH
uniprot id: A0A8B7GYT4
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

30608:NCOA3
gene id: 30608:NCOA3
uniprot id: A0A8B7ETC1
uniprot id: A0A8B7ETC5
uniprot id: A0A8B7EV75
uniprot id: A0A8B7EVC7
uniprot id: A0A8B7WQH4
uniprot id: A0A8B7WQH6
uniprot id: A0A8B7WQL8
uniprot id: A0A8B7WRZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

30608:BEX4
gene id: 30608:BEX4
uniprot id: A0A8B7I1E2
names: Similarity
messages: Belongs to the BEX family.

30608:TPI1
gene id: 30608:TPI1
uniprot id: A0A8B7G317
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

30608:ITGB5
gene id: 30608:ITGB5
uniprot id: A0A8B7X4E2
uniprot id: A0A8C5YJ65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

30608:XRCC1
gene id: 30608:XRCC1
uniprot id: A0A8B7G3I7
uniprot id: A0A8B7G3J5
uniprot id: A0A8B7G4C7
names: Subcellular Location Annotation
messages: Nucleus

30608:RIC3
gene id: 30608:RIC3
uniprot id: A0A8B7HNT7
uniprot id: A0A8C5XHZ8
names: Similarity
messages: Belongs to the ric-3 family.

30608:SLC25A22
gene id: 30608:SLC25A22
uniprot id: A0A8C5ULT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:FOXI2
gene id: 30608:FOXI2
uniprot id: A0A8B7HK47
names: Subcellular Location Annotation
messages: Nucleus

30608:SERPINB7
gene id: 30608:SERPINB7
uniprot id: A0A8B7H1B3
uniprot id: A0A8B7H1B9
uniprot id: A0A8C5XL68
names: Similarity
messages: Belongs to the serpin family.

30608:HNRNPU
gene id: 30608:HNRNPU
uniprot id: A0A8B7FFK6
uniprot id: A0A8C5VNL7
names: Subcellular Location Annotation
messages: Nucleus

30608:CENPK
gene id: 30608:CENPK
uniprot id: A0A8B7HRJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-K/MCM22 family.
messages: Nucleus
messages: centromere

30608:TMEM59
gene id: 30608:TMEM59
uniprot id: A0A8B7H5S8
uniprot id: A0A8B7H5T3
uniprot id: A0A8B7H5U5
uniprot id: A0A8B7H852
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:TPX2
gene id: 30608:TPX2
uniprot id: A0A8B7FN22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPX2 family.
messages: Nucleus
messages: spindle pole

30608:NUF2
gene id: 30608:NUF2
uniprot id: A0A8C5VIC7
names: Similarity
messages: Belongs to the NUF2 family.

30608:LOC105871783
gene id: 30608:LOC105871783
uniprot id: A0A8B7GAU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

30608:AIM1L
gene id: 30608:AIM1L
uniprot id: A0A8B7FCP8
uniprot id: A0A8B7FDH2
uniprot id: A0A8B7WM09
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

30608:IL10
gene id: 30608:IL10
uniprot id: A0A8B7G1S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

30608:SCIN
gene id: 30608:SCIN
uniprot id: A0A8C5XHD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: cytoskeleton
messages: podosome

30608:ETV3
gene id: 30608:ETV3
uniprot id: A0A8B7GJL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus
messages: Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity.

30608:LOC105855598
gene id: 30608:LOC105855598
uniprot id: A0A8C5V9S1
names: Subcellular Location Annotation
messages: Membrane

30608:SET
gene id: 30608:SET
uniprot id: A0A8B7XBL6
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

30608:MBOAT4
gene id: 30608:MBOAT4
uniprot id: A0A8B7HP98
uniprot id: A0A8B7HQX4
uniprot id: A0A8B7HRN6
uniprot id: A0A8C5YE07
names: Subcellular Location Annotation
messages: Membrane

30608:ARPC5
gene id: 30608:ARPC5
uniprot id: A0A8B7EB47
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

30608:TMEM170B
gene id: 30608:TMEM170B
uniprot id: A0A8B7FK91
uniprot id: A0A8B7FKD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

30608:FAM160A1
gene id: 30608:FAM160A1
uniprot id: A0A8B7HPS2
names: Similarity
messages: Belongs to the FHIP family.

30608:AMZ2
gene id: 30608:AMZ2
uniprot id: A0A8C5XKX9
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

30608:HIF3A
gene id: 30608:HIF3A
uniprot id: A0A8B7G452
uniprot id: A0A8B7G456
uniprot id: A0A8B7G4Y4
uniprot id: A0A8C5VE15
names: Subcellular Location Annotation
messages: Nucleus
messages: Nucleus speckle

30608:PLXNB2
gene id: 30608:PLXNB2
uniprot id: A0A8B7I2R5
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PHGDH
gene id: 30608:PHGDH
uniprot id: A0A8B7G524
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

30608:LOC109729806
gene id: 30608:LOC109729806
uniprot id: A0A8B7WU50
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Heterodimer with ADAM1/fertilin subunit alpha.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.

30608:PLA2G4B
gene id: 30608:PLA2G4B
uniprot id: A0A8B7GGQ2
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

30608:LOC105870320
gene id: 30608:LOC105870320
uniprot id: A0A8B7WM50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

30608:NFKB2
gene id: 30608:NFKB2
uniprot id: A0A8B7GQ05
uniprot id: A0A8B7GQB1
uniprot id: A0A8C5W364
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:TAAR3
gene id: 30608:TAAR3
uniprot id: A0A8C5XFK8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:PAPPA
gene id: 30608:PAPPA
uniprot id: A0A8B7GMQ3
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LMX1B
gene id: 30608:LMX1B
uniprot id: A0A8B7GV86
uniprot id: A0A8B7GVE0
uniprot id: A0A8B7XBB2
names: Subcellular Location Annotation
messages: Nucleus

30608:NMUR1
gene id: 30608:NMUR1
uniprot id: A0A8B7G2U5
uniprot id: A0A8B7G2V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

30608:SNU13
gene id: 30608:SNU13
uniprot id: A0A8C5VN66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

30608:LOC105875822
gene id: 30608:LOC105875822
uniprot id: A0A8C5W6L8
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

30608:GNB1
gene id: 30608:GNB1
uniprot id: A0A8B7WNM6
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

30608:MRPL41
gene id: 30608:MRPL41
uniprot id: A0A8B7HPW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

30608:PDE9A
gene id: 30608:PDE9A
uniprot id: A0A8B7HCJ1
uniprot id: A0A8B7HCK4
uniprot id: A0A8B7WXX0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

30608:LOC105861123
gene id: 30608:LOC105861123
uniprot id: A0A8C5XJ54
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

30608:LOC105854833
gene id: 30608:LOC105854833
uniprot id: A0A8B7ECE9
uniprot id: A0A8C5XPZ8
names: Similarity
messages: Belongs to the MHC class I family.

30608:TRIM56
gene id: 30608:TRIM56
uniprot id: A0A8B7FZB4
uniprot id: A0A8B7G0J6
names: Similarity
messages: Belongs to the TRIM/RBCC family.

30608:PGAP1
gene id: 30608:PGAP1
uniprot id: A0A8B7H7B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

30608:ADPRHL1
gene id: 30608:ADPRHL1
uniprot id: A0A8B7GE83
uniprot id: A0A8B7GER2
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

30608:FAM114A1
gene id: 30608:FAM114A1
uniprot id: A0A8B7FL78
uniprot id: A0A8B7FLD5
uniprot id: A0A8B7FMK3
uniprot id: A0A8B7FMK7
names: Similarity
messages: Belongs to the FAM114 family.

30608:GAPDH
gene id: 30608:GAPDH
uniprot id: A0A8B7G1N6
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

30608:LOC105872035
gene id: 30608:LOC105872035
uniprot id: A0A8B7GFB2
names: Similarity
messages: Belongs to the intermediate filament family.

30608:CREG2
gene id: 30608:CREG2
uniprot id: A0A8B7EPG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

30608:PRKCB
gene id: 30608:PRKCB
uniprot id: A0A8B7HF00
uniprot id: A0A8B7HFH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Membrane
messages: Nucleus

30608:TTR
gene id: 30608:TTR
uniprot id: A0A8B7HLR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transthyretin family.
messages: Homotetramer. Dimer of dimers. In the homotetramer, subunits assemble around a central channel that can accommodate two ligand molecules. Interacts with RBP4.
messages: Secreted
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

30608:CETN1
gene id: 30608:CETN1
uniprot id: A0A8B7F0S7
names: Similarity
messages: Belongs to the centrin family.

30608:EIF2D
gene id: 30608:EIF2D
uniprot id: A0A8B7G1I6
uniprot id: A0A8B7G2F1
uniprot id: A0A8C5V6J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF2D family.
messages: Cytoplasm
messages: Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner. The binding of Met-tRNA(I) occurs after the AUG codon finds its position in the P-site of 40S ribosomes, the situation that takes place during initiation complex formation on some specific RNAs. Its activity in tRNA binding with 40S subunits does not require the presence of the aminoacyl moiety. Possesses the unique ability to deliver non-Met (elongator) tRNAs into the P-site of the 40S subunit. In addition to its role in initiation, can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits.

30608:POU5F2
gene id: 30608:POU5F2
uniprot id: A0A8B7FFW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-5 subfamily.
messages: Nucleus

30608:LOC105863401
gene id: 30608:LOC105863401
uniprot id: A0A8B7FCH4
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

30608:ERGIC3
gene id: 30608:ERGIC3
uniprot id: A0A8B7FPJ8
uniprot id: A0A8C5XVK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

30608:TSR2
gene id: 30608:TSR2
uniprot id: A0A8B7WZB4
uniprot id: A0A8C5V3M7
names: Function
names: Similarity
messages: Belongs to the TSR2 family.
messages: May be involved in 20S pre-rRNA processing.

30608:SYNE1
gene id: 30608:SYNE1
uniprot id: A0A8B7X534
uniprot id: A0A8B7X539
uniprot id: A0A8B7X540
uniprot id: A0A8B7X5P1
uniprot id: A0A8B7X6U3
uniprot id: A0A8B7X6U8
uniprot id: A0A8B7X702
uniprot id: A0A8B7X708
names: Similarity
messages: Belongs to the nesprin family.

30608:TM4SF4
gene id: 30608:TM4SF4
uniprot id: A0A8C5YIX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

30608:THY1
gene id: 30608:THY1
uniprot id: A0A8C5YDW9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
messages: Membrane

30608:NR3C1
gene id: 30608:NR3C1
uniprot id: A0A8B7F8V0
uniprot id: A0A8C5XRP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

30608:ARMCX2
gene id: 30608:ARMCX2
uniprot id: A0A8B7GJ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eutherian X-chromosome-specific Armcx family.
messages: Membrane

30608:LOC105857794
gene id: 30608:LOC105857794
uniprot id: A0A8B7WYT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

30608:PPP2R2A
gene id: 30608:PPP2R2A
uniprot id: A0A8B7WSM8
uniprot id: A0A8B7WSQ9
uniprot id: A0A8B7WU60
uniprot id: A0A8C5XGC4
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

30608:TSHZ1
gene id: 30608:TSHZ1
uniprot id: A0A8B7G647
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

30608:RBBP5
gene id: 30608:RBBP5
uniprot id: A0A8B7FZT4
uniprot id: A0A8B7FZX7
uniprot id: A0A8B7FZY3
uniprot id: A0A8B7G0L6
uniprot id: A0A8B7G0M2
uniprot id: A0A8B7G120
uniprot id: A0A8B7G151
uniprot id: A0A8B7WYS7
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105869754
gene id: 30608:LOC105869754
uniprot id: A0A8B7G5P7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LOC105869816
gene id: 30608:LOC105869816
uniprot id: A0A8C5VXC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Golgi pH regulator (TC 1.A.38) family.
messages: Membrane

30608:SUPT6H
gene id: 30608:SUPT6H
uniprot id: A0A8B7EME2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).

30608:LOC105868421
gene id: 30608:LOC105868421
uniprot id: A0A8B7G047
names: Similarity
messages: Belongs to the MHC class I family.

30608:PGD
gene id: 30608:PGD
uniprot id: A0A8B7WRA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

30608:IDH3B
gene id: 30608:IDH3B
uniprot id: A0A8B7FNY2
uniprot id: A0A8B7FP51
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

30608:SCRIB
gene id: 30608:SCRIB
uniprot id: A0A8B7G0W8
uniprot id: A0A8B7G0X5
uniprot id: A0A8B7G0Y0
uniprot id: A0A8B7G284
uniprot id: A0A8C5XX21
uniprot id: A0A8C6EID1
names: Similarity
messages: Belongs to the LAP (LRR and PDZ) protein family.

30608:RPRM
gene id: 30608:RPRM
uniprot id: A0A8B7HEW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reprimo family.
messages: Cytoplasm
messages: Membrane

30608:LOC105859457
gene id: 30608:LOC105859457
uniprot id: A0A8B7EW46
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:NXT1
gene id: 30608:NXT1
uniprot id: A0A8B7EJE8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

30608:LOC105861232
gene id: 30608:LOC105861232
uniprot id: A0A8B7F414
names: Similarity
messages: Belongs to the GAGE family.

30608:ME2
gene id: 30608:ME2
uniprot id: A0A8B7GQ26
uniprot id: A0A8B7GQC5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

30608:LOC105880097
gene id: 30608:LOC105880097
uniprot id: A0A8B7HGQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

30608:LOC105877948
gene id: 30608:LOC105877948
uniprot id: A0A8B7X962
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

30608:SLC2A8
gene id: 30608:SLC2A8
uniprot id: A0A8B7GVI1
uniprot id: A0A8C5XQQ9
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

30608:PLA2G4D
gene id: 30608:PLA2G4D
uniprot id: A0A8B7X3A3
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

30608:LOC105881308
gene id: 30608:LOC105881308
uniprot id: A0A8B7WZ11
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Monomer.

30608:PPP1R14B
gene id: 30608:PPP1R14B
uniprot id: A0A8B7H9L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Inhibitor of PPP1CA.
messages: Membrane

30608:LOC105866516
gene id: 30608:LOC105866516
uniprot id: A0A8B7FQU7
names: Subcellular Location Annotation
messages: Membrane

30608:TOM1L1
gene id: 30608:TOM1L1
uniprot id: A0A8B7GYY9
uniprot id: A0A8B7WN66
names: Similarity
messages: Belongs to the TOM1 family.

30608:LOC105855602
gene id: 30608:LOC105855602
uniprot id: A0A8B7ECN8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:TSHR
gene id: 30608:TSHR
uniprot id: A0A8B7FXG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

30608:TMC3
gene id: 30608:TMC3
uniprot id: A0A8C5YDK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

30608:OSBPL10
gene id: 30608:OSBPL10
uniprot id: A0A8B7GPT8
uniprot id: A0A8B7WNL8
uniprot id: A0A8B7WNN9
uniprot id: A0A8B7WNR6
names: Similarity
messages: Belongs to the OSBP family.

30608:IGFBP3
gene id: 30608:IGFBP3
uniprot id: A0A8B7G959
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:ACTL7B
gene id: 30608:ACTL7B
uniprot id: A0A8B7EDH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: cytoskeleton

30608:MAML1
gene id: 30608:MAML1
uniprot id: A0A8C5VDQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

30608:CNMD
gene id: 30608:CNMD
uniprot id: A0A8B7GCS7
uniprot id: A0A8C5VXH7
names: Similarity
messages: Belongs to the chondromodulin-1 family.

30608:IRGQ
gene id: 30608:IRGQ
uniprot id: A0A8B7G3K2
uniprot id: A0A8B7G4Y7
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

30608:TIMP2
gene id: 30608:TIMP2
uniprot id: A0A8B7FSE9
uniprot id: A0A8C5VP97
names: Similarity
names: Subunit
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: Interacts (via the C-terminal) with MMP2 (via the C-terminal PEX domain); the interaction inhibits the MMP2 activity.

30608:TMEM176B
gene id: 30608:TMEM176B
uniprot id: A0A8B7HU79
names: Similarity
messages: Belongs to the TMEM176 family.

30608:TSEN2
gene id: 30608:TSEN2
uniprot id: A0A8B7HS31
uniprot id: A0A8B7HS52
uniprot id: A0A8B7HUC9
uniprot id: A0A8B7HUD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

30608:USP44
gene id: 30608:USP44
uniprot id: A0A8B7H3D1
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

30608:DPYSL4
gene id: 30608:DPYSL4
uniprot id: A0A8B7HHZ4
uniprot id: A0A8C5UIL6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

30608:PRKG1
gene id: 30608:PRKG1
uniprot id: A0A8B7G7R3
uniprot id: A0A8B7G7R5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

30608:TLR4
gene id: 30608:TLR4
uniprot id: A0A8B7GMC5
uniprot id: A0A8B7GMD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

30608:SLC29A1
gene id: 30608:SLC29A1
uniprot id: A0A8B7EUB0
uniprot id: A0A8B7EUB3
uniprot id: A0A8B7EUB5
uniprot id: A0A8B7EUC1
uniprot id: A0A8B7EWA5
uniprot id: A0A8B7EWA7
uniprot id: A0A8B7EWB0
uniprot id: A0A8B7EWB2
uniprot id: A0A8B7EWB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

30608:LOC105858337
gene id: 30608:LOC105858337
uniprot id: A0A8B7ERJ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:UBR3
gene id: 30608:UBR3
uniprot id: A0A8B7X896
uniprot id: A0A8B7X8A1
uniprot id: A0A8B7X8A4
uniprot id: A0A8B7X8Z2
uniprot id: A0A8B7X8Z7
uniprot id: A0A8B7XA99
uniprot id: A0A8B7XAA5
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

30608:LOC105868720
gene id: 30608:LOC105868720
uniprot id: A0A8B7G074
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:GLOD4
gene id: 30608:GLOD4
uniprot id: A0A8B7EMC9
names: Similarity
messages: Belongs to the glyoxalase I family.

30608:CLPX
gene id: 30608:CLPX
uniprot id: A0A8B7X2V8
names: Similarity
messages: Belongs to the ClpX chaperone family.

30608:FUT9
gene id: 30608:FUT9
uniprot id: A0A8B7GPL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Membrane

30608:ALAS1
gene id: 30608:ALAS1
uniprot id: A0A8B7WL26
uniprot id: A0A8B7WLV2
uniprot id: A0A8C5ULR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

30608:LOC105861262
gene id: 30608:LOC105861262
uniprot id: A0A8B7F2I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:AK6
gene id: 30608:AK6
uniprot id: A0A8B7HLV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
messages: Cajal body
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer. Interacts with COIL (via C-terminus).
messages: nucleoplasm

30608:AKR1D1
gene id: 30608:AKR1D1
uniprot id: A0A8B7EUG5
names: Similarity
messages: Belongs to the aldo/keto reductase family.

30608:CA2
gene id: 30608:CA2
uniprot id: A0A8B7H0U0
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

30608:PPFIBP2
gene id: 30608:PPFIBP2
uniprot id: A0A8B7EWD6
uniprot id: A0A8B7EWD7
uniprot id: A0A8B7EWE6
uniprot id: A0A8B7EWE7
uniprot id: A0A8B7EWE9
uniprot id: A0A8B7EWF5
uniprot id: A0A8B7EWF8
uniprot id: A0A8B7EWG0
uniprot id: A0A8B7EWG3
uniprot id: A0A8B7EWG4
uniprot id: A0A8B7EYB6
uniprot id: A0A8B7EYC0
uniprot id: A0A8B7EYC4
uniprot id: A0A8B7EYC9
uniprot id: A0A8B7EYD4
uniprot id: A0A8B7EYD8
uniprot id: A0A8B7EYF0
uniprot id: A0A8B7EYF5
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

30608:ADGRA2
gene id: 30608:ADGRA2
uniprot id: A0A8B7G7T7
uniprot id: A0A8B7G8H6
names: Subcellular Location Annotation
messages: Membrane

30608:GRIN1
gene id: 30608:GRIN1
uniprot id: A0A8B7HPW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

30608:OLFML1
gene id: 30608:OLFML1
uniprot id: A0A8B7EWG6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105883593
gene id: 30608:LOC105883593
uniprot id: A0A8B7HW12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEXIM family.
messages: Nucleus

30608:FXR1
gene id: 30608:FXR1
uniprot id: A0A8B7EDF7
uniprot id: A0A8B7EDG5
uniprot id: A0A8B7EDG9
uniprot id: A0A8B7EE22
uniprot id: A0A8B7EE33
uniprot id: A0A8B7EG31
uniprot id: A0A8B7EG37
names: Similarity
messages: Belongs to the FMR1 family.

30608:ISOC2
gene id: 30608:ISOC2
uniprot id: A0A8B7FC15
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isochorismatase family.
messages: Cytoplasm
messages: Interacts with CDKN2A.
messages: Nucleus

30608:MED30
gene id: 30608:MED30
uniprot id: A0A8B7FE98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

30608:AQP8
gene id: 30608:AQP8
uniprot id: A0A8B7HFE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

30608:LOC105867900
gene id: 30608:LOC105867900
uniprot id: A0A8B7FWJ1
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105859211
gene id: 30608:LOC105859211
uniprot id: A0A8B7EV10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LIN9
gene id: 30608:LIN9
uniprot id: A0A8C5W532
names: Similarity
messages: Belongs to the lin-9 family.

30608:ADAM7
gene id: 30608:ADAM7
uniprot id: A0A8B7H0Z1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:COPZ2
gene id: 30608:COPZ2
uniprot id: A0A8B7GG87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

30608:APOL5
gene id: 30608:APOL5
uniprot id: A0A8B7HWM1
names: Similarity
messages: Belongs to the apolipoprotein L family.

30608:WNT11
gene id: 30608:WNT11
uniprot id: A0A8B7F0K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

30608:LOC109730222
gene id: 30608:LOC109730222
uniprot id: A0A8B7WYP6
names: Subcellular Location Annotation
messages: Membrane

30608:CAMTA1
gene id: 30608:CAMTA1
uniprot id: A0A8B7I7M5
uniprot id: A0A8B7I9I9
uniprot id: A0A8B7IAV3
uniprot id: A0A8B7WQB9
uniprot id: A0A8B7WQC4
uniprot id: A0A8B7WQC8
uniprot id: A0A8B7WQD3
uniprot id: A0A8B7WQD8
uniprot id: A0A8B7WQE0
uniprot id: A0A8B7WQE5
uniprot id: A0A8B7WQE6
uniprot id: A0A8B7WQF1
uniprot id: A0A8B7WQF8
uniprot id: A0A8B7WQG3
uniprot id: A0A8B7WQG4
uniprot id: A0A8B7WQH0
uniprot id: A0A8B7WQH5
uniprot id: A0A8B7WRV0
uniprot id: A0A8B7WRV4
uniprot id: A0A8B7WRW5
names: Similarity
names: Subunit
messages: Belongs to the CAMTA family.
messages: May interact with calmodulin.

30608:LOC105883465
gene id: 30608:LOC105883465
uniprot id: A0A8B7HVD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:UNC5CL
gene id: 30608:UNC5CL
uniprot id: A0A8B7G2H3
uniprot id: A0A8B7G2I0
names: Similarity
messages: Belongs to the unc-5 family.

30608:PSD
gene id: 30608:PSD
uniprot id: A0A8C5UYC2
names: Subcellular Location Annotation
messages: ruffle membrane

30608:FNIP1
gene id: 30608:FNIP1
uniprot id: A0A8B7WRR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

30608:GSTK1
gene id: 30608:GSTK1
uniprot id: A0A8B7GKN4
names: Similarity
messages: Belongs to the GST superfamily. Kappa family.

30608:LOC105884901
gene id: 30608:LOC105884901
uniprot id: A0A8B7I248
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

30608:TULP2
gene id: 30608:TULP2
uniprot id: A0A8B7FLT4
uniprot id: A0A8B7FLT9
uniprot id: A0A8B7FM06
uniprot id: A0A8B7FM26
uniprot id: A0A8B7FM27
names: Similarity
messages: Belongs to the TUB family.

30608:HS3ST5
gene id: 30608:HS3ST5
uniprot id: A0A8C5VKX4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:C22H19orf12
gene id: 30608:C22H19orf12
uniprot id: A0A8B7H339
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

30608:CMTR1
gene id: 30608:CMTR1
uniprot id: A0A8B7F403
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with POLR2A (via C-terminus).
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1).
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.

30608:LOC105863954
gene id: 30608:LOC105863954
uniprot id: A0A8B7FF81
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

30608:IPO4
gene id: 30608:IPO4
uniprot id: A0A8B7FR35
names: Subcellular Location Annotation
messages: Cytoplasm

30608:ADCK5
gene id: 30608:ADCK5
uniprot id: A0A8C5V3W8
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

30608:PFN3
gene id: 30608:PFN3
uniprot id: A0A8B7HX65
names: Similarity
messages: Belongs to the profilin family.

30608:MEIS3
gene id: 30608:MEIS3
uniprot id: A0A8B7G551
uniprot id: A0A8B7G5Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

30608:LOC105861272
gene id: 30608:LOC105861272
uniprot id: A0A8B7F2J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LHX4
gene id: 30608:LHX4
uniprot id: A0A8B7WZ17
names: Subcellular Location Annotation
messages: Nucleus

30608:SERPINB8
gene id: 30608:SERPINB8
uniprot id: A0A8B7H3D4
uniprot id: A0A8C5VSK1
names: Similarity
messages: Belongs to the serpin family.

30608:ZIC5
gene id: 30608:ZIC5
uniprot id: A0A8C6EGE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

30608:TGFBR1
gene id: 30608:TGFBR1
uniprot id: A0A8B7GN03
uniprot id: A0A8B7GNA5
uniprot id: A0A8C5Y1Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

30608:PLXNA4
gene id: 30608:PLXNA4
uniprot id: A0A8B7EKP9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:CHD3
gene id: 30608:CHD3
uniprot id: A0A8B7WMS5
uniprot id: A0A8B7WMS9
uniprot id: A0A8B7WMT1
uniprot id: A0A8B7WMT5
uniprot id: A0A8B7WMT8
uniprot id: A0A8B7WMU2
uniprot id: A0A8B7WMU4
uniprot id: A0A8B7WMU9
uniprot id: A0A8B7WMV6
uniprot id: A0A8B7WMX1
uniprot id: A0A8B7WMY3
uniprot id: A0A8B7WNZ9
uniprot id: A0A8B7WP08
uniprot id: A0A8B7WP14
uniprot id: A0A8C5XCW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

30608:BDKRB1
gene id: 30608:BDKRB1
uniprot id: A0A8B7I8C4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.

30608:LOC105865649
gene id: 30608:LOC105865649
uniprot id: A0A8B7FMC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:COPB1
gene id: 30608:COPB1
uniprot id: A0A8C5VWR5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Endoplasmic reticulum-Golgi intermediate compartment
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

30608:OVCH1
gene id: 30608:OVCH1
uniprot id: A0A8B7WTR1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ITPKA
gene id: 30608:ITPKA
uniprot id: A0A8C5V6M2
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

30608:EIF3J
gene id: 30608:EIF3J
uniprot id: A0A8B7GI34
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl (A) site. It may regulate the interaction between the 43S PIC and mRNA.
messages: Cytoplasm
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.

30608:PSMB7
gene id: 30608:PSMB7
uniprot id: A0A8C5XWI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB7 displays a trypsin-like activity.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is a barrel-shaped complex made of 28 subunits that are arranged in four stacked rings. The two outer rings are each formed by seven alpha subunits, and the two inner rings are formed by seven beta subunits. The proteolytic activity is exerted by three beta-subunits PSMB5, PSMB6 and PSMB7.

30608:SLC17A8
gene id: 30608:SLC17A8
uniprot id: A0A8B7HZZ9
names: Subcellular Location Annotation
messages: Membrane

30608:SLC35C2
gene id: 30608:SLC35C2
uniprot id: A0A8B7ETE3
uniprot id: A0A8B7EVD9
uniprot id: A0A8C5XKT7
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105878850
gene id: 30608:LOC105878850
uniprot id: A0A8C5VG56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MNAT1
gene id: 30608:MNAT1
uniprot id: A0A8C5VGZ2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with CDK7 and cyclin H.
messages: Nucleus
messages: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.

30608:PRRX1
gene id: 30608:PRRX1
uniprot id: A0A8B7GDZ9
uniprot id: A0A8B7GE71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

30608:LOC105864730
gene id: 30608:LOC105864730
uniprot id: A0A8B7FI72
uniprot id: A0A8B7X323
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

30608:SLC25A35
gene id: 30608:SLC25A35
uniprot id: A0A8C5V6M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:S100PBP
gene id: 30608:S100PBP
uniprot id: A0A8B7GDT4
uniprot id: A0A8B7GEQ3
names: Subcellular Location Annotation
messages: Nucleus

30608:MZF1
gene id: 30608:MZF1
uniprot id: A0A8B7WUR1
uniprot id: A0A8B7WUY5
names: Subcellular Location Annotation
messages: Nucleus

30608:NGB
gene id: 30608:NGB
uniprot id: A0A8C5Y5M2
names: Similarity
messages: Belongs to the globin family.

30608:UTP3
gene id: 30608:UTP3
uniprot id: A0A8B7HTM1
names: Similarity
messages: Belongs to the SAS10 family.

30608:OGDHL
gene id: 30608:OGDHL
uniprot id: A0A8B7EXI8
uniprot id: A0A8B7EZD9
uniprot id: A0A8B7WLC7
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

30608:RABEP2
gene id: 30608:RABEP2
uniprot id: A0A8B7FY11
uniprot id: A0A8B7FY28
uniprot id: A0A8B7FZ62
uniprot id: A0A8C5URL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Early endosome
messages: Endosome
messages: centrosome
messages: cilium basal body

30608:LCAT
gene id: 30608:LCAT
uniprot id: A0A8B7ETS6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

30608:GSX2
gene id: 30608:GSX2
uniprot id: A0A8B7G684
names: Subcellular Location Annotation
messages: Nucleus

30608:MLF2
gene id: 30608:MLF2
uniprot id: A0A8B7G1S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

30608:HPRT1
gene id: 30608:HPRT1
uniprot id: A0A8B7GCU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

30608:KPNA7
gene id: 30608:KPNA7
uniprot id: A0A8B7FYA3
uniprot id: A0A8B7FZF7
uniprot id: A0A8B7WPA3
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

30608:HYAL3
gene id: 30608:HYAL3
uniprot id: A0A8B7GTU2
uniprot id: A0A8B7GVM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Early endosome
messages: Endoplasmic reticulum
messages: Endosome
messages: Membrane
messages: acrosome

30608:LOC105859217
gene id: 30608:LOC105859217
uniprot id: A0A8B7EV14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105864291
gene id: 30608:LOC105864291
uniprot id: A0A8B7FGF3
uniprot id: A0A8B7FGG0
uniprot id: A0A8B7FGJ2
uniprot id: A0A8B7FGJ6
uniprot id: A0A8B7FGK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

30608:TTC27
gene id: 30608:TTC27
uniprot id: A0A8C5XT10
names: Similarity
messages: Belongs to the TTC27 family.

30608:NPC1
gene id: 30608:NPC1
uniprot id: A0A8B7F164
uniprot id: A0A8B7F166
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

30608:TAAR4
gene id: 30608:TAAR4
uniprot id: A0A8B7ECC8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:ITGB2
gene id: 30608:ITGB2
uniprot id: A0A8B7HF09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

30608:PROX1
gene id: 30608:PROX1
uniprot id: A0A8C5V2D7
names: Subcellular Location Annotation
messages: Nucleus

30608:TMEM237
gene id: 30608:TMEM237
uniprot id: A0A8B7EIH8
uniprot id: A0A8B7EII0
uniprot id: A0A8B7EJK6
uniprot id: A0A8B7EKY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM237 family.
messages: Component of the transition zone in primary cilia. Required for ciliogenesis.
messages: Membrane
messages: cilium

30608:NPBWR1
gene id: 30608:NPBWR1
uniprot id: A0A8B7I3V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:FOXA2
gene id: 30608:FOXA2
uniprot id: A0A8B7EK75
uniprot id: A0A8C5XFX6
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105884133
gene id: 30608:LOC105884133
uniprot id: A0A8B7X415
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105872752
gene id: 30608:LOC105872752
uniprot id: A0A8B7GIN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PXN
gene id: 30608:PXN
uniprot id: A0A8B7FSX4
uniprot id: A0A8B7WSZ6
uniprot id: A0A8B7WSZ8
uniprot id: A0A8B7WT01
uniprot id: A0A8B7WT04
uniprot id: A0A8B7WT41
uniprot id: A0A8B7WTA1
uniprot id: A0A8B7WTB0
uniprot id: A0A8B7WUJ8
names: Subcellular Location Annotation
messages: cell cortex
messages: cytoskeleton
messages: focal adhesion

30608:EIF1AX
gene id: 30608:EIF1AX
uniprot id: A0A8B7HQG3
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

30608:VPS41
gene id: 30608:VPS41
uniprot id: A0A8B7H8S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network

30608:ADCY7
gene id: 30608:ADCY7
uniprot id: A0A8B7WRU7
uniprot id: A0A8B7WRV8
uniprot id: A0A8C5V973
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

30608:SAMM50
gene id: 30608:SAMM50
uniprot id: A0A8B7X8A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

30608:CACNA1B
gene id: 30608:CACNA1B
uniprot id: A0A8B7XBK7
uniprot id: A0A8B7XBK8
uniprot id: A0A8B7XCI2
uniprot id: A0A8B7XDB0
uniprot id: A0A8B7XDT2
uniprot id: A0A8B7XDT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1B subfamily.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This alpha-1B subunit gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group. They are involved in pain signaling. Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.

30608:FAM53C
gene id: 30608:FAM53C
uniprot id: A0A8C5XIG9
names: Similarity
messages: Belongs to the FAM53 family.

30608:LOC105872554
gene id: 30608:LOC105872554
uniprot id: A0A8B7GH93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

30608:LOC105855981
gene id: 30608:LOC105855981
uniprot id: A0A8B7XF40
names: Subcellular Location Annotation
messages: Chromosome

30608:MOS
gene id: 30608:MOS
uniprot id: A0A8B7H0N7
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:FOXH1
gene id: 30608:FOXH1
uniprot id: A0A8B7G145
uniprot id: A0A8B7G2G4
uniprot id: A0A8C5V9M6
names: Subcellular Location Annotation
messages: Nucleus

30608:NIPAL3
gene id: 30608:NIPAL3
uniprot id: A0A8B7FD55
uniprot id: A0A8B7FD79
uniprot id: A0A8B7FE10
uniprot id: A0A8B7WMC4
uniprot id: A0A8C5VX56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

30608:SLC9A9
gene id: 30608:SLC9A9
uniprot id: A0A8B7G6C8
uniprot id: A0A8B7G736
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Endosome membrane
messages: Membrane

30608:TRMT5
gene id: 30608:TRMT5
uniprot id: A0A8B7H8X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

30608:LOC109729436
gene id: 30608:LOC109729436
uniprot id: A0A8B7WM23
names: Similarity
messages: Belongs to the peptidase M14 family.

30608:PSMB3
gene id: 30608:PSMB3
uniprot id: A0A8B7GFB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

30608:LOC105885969
gene id: 30608:LOC105885969
uniprot id: A0A8B7X1Z9
names: Subcellular Location Annotation
messages: Membrane

30608:SDC1
gene id: 30608:SDC1
uniprot id: A0A8B7HY83
uniprot id: A0A8B7I097
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane
messages: extracellular exosome

30608:LOC105878175
gene id: 30608:LOC105878175
uniprot id: A0A8B7WUF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative pheromone receptor.

30608:RNASEH2A
gene id: 30608:RNASEH2A
uniprot id: A0A8B7WW50
uniprot id: A0A8B7WW52
uniprot id: A0A8B7WWU7
uniprot id: A0A8B7WXU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

30608:ITGA7
gene id: 30608:ITGA7
uniprot id: A0A8B7FJX3
uniprot id: A0A8B7FJY9
uniprot id: A0A8C5VC58
uniprot id: A0A8C5W894
uniprot id: A0A8C5Y377
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

30608:ACRBP
gene id: 30608:ACRBP
uniprot id: A0A8B7G1Q9
uniprot id: A0A8B7G355
names: Subcellular Location Annotation
messages: acrosome

30608:NIPAL1
gene id: 30608:NIPAL1
uniprot id: A0A8B7GSM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

30608:LOC105877188
gene id: 30608:LOC105877188
uniprot id: A0A8B7WUI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative pheromone receptor.

30608:DSP
gene id: 30608:DSP
uniprot id: A0A8B7FKA5
uniprot id: A0A8B7FKE8
names: Subcellular Location Annotation
messages: cytoskeleton

30608:LOC105875329
gene id: 30608:LOC105875329
uniprot id: A0A8B7GW24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PFDN1
gene id: 30608:PFDN1
uniprot id: A0A8B7F8Y4
uniprot id: A0A8B7F8Z5
uniprot id: A0A8B7F9F6
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

30608:TMEM150B
gene id: 30608:TMEM150B
uniprot id: A0A8B7H680
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105881712
gene id: 30608:LOC105881712
uniprot id: A0A8B7HMT6
uniprot id: A0A8B7HMY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

30608:ZNF24
gene id: 30608:ZNF24
uniprot id: A0A8B7ER89
names: Subcellular Location Annotation
messages: Nucleus

30608:GTPBP10
gene id: 30608:GTPBP10
uniprot id: A0A8B7HDM7
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

30608:DIP2A
gene id: 30608:DIP2A
uniprot id: A0A8B7WY76
uniprot id: A0A8B7WY81
uniprot id: A0A8B7WZ42
uniprot id: A0A8B7WZ50
uniprot id: A0A8B7WZY4
uniprot id: A0A8C5UWL6
uniprot id: A0A8C5VEV0
uniprot id: A0A8C5VUY7
names: Similarity
messages: Belongs to the DIP2 family.

30608:BARX2
gene id: 30608:BARX2
uniprot id: A0A8B7FF78
uniprot id: A0A8B7FFF1
names: Subcellular Location Annotation
messages: Nucleus

30608:KIF17
gene id: 30608:KIF17
uniprot id: A0A8B7HY12
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:EIF1
gene id: 30608:EIF1
uniprot id: A0A8B7GFP0
names: Similarity
messages: Belongs to the SUI1 family.

30608:CDSN
gene id: 30608:CDSN
uniprot id: A0A8B7ENR2
names: Function
names: Subcellular Location Annotation
messages: Important for the epidermal barrier integrity.
messages: Secreted

30608:SERPINA1
gene id: 30608:SERPINA1
uniprot id: A0A8B7EIL3
names: Similarity
messages: Belongs to the serpin family.

30608:LOC105874586
gene id: 30608:LOC105874586
uniprot id: A0A8B7X5M7
names: Similarity
messages: Belongs to the peptidase M10A family.

30608:CCL17
gene id: 30608:CCL17
uniprot id: A0A8B7FF65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

30608:LOC105862727
gene id: 30608:LOC105862727
uniprot id: A0A8C5VCJ6
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

30608:KCNQ5
gene id: 30608:KCNQ5
uniprot id: A0A8B7FL99
uniprot id: A0A8B7FLF1
uniprot id: A0A8B7FLG1
uniprot id: A0A8B7FLG2
uniprot id: A0A8B7FMM1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:TTC38
gene id: 30608:TTC38
uniprot id: A0A8B7FUN0
uniprot id: A0A8B7X8C1
names: Similarity
messages: Belongs to the TTC38 family.

30608:SRRT
gene id: 30608:SRRT
uniprot id: A0A8B7FYL6
uniprot id: A0A8B7FZH2
uniprot id: A0A8C5UVU8
names: Similarity
messages: Belongs to the ARS2 family.

30608:CBLC
gene id: 30608:CBLC
uniprot id: A0A8B7G4M5
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

30608:PTGER2
gene id: 30608:PTGER2
uniprot id: A0A8B7FW10
uniprot id: A0A8B7FWU1
uniprot id: A0A8B7X148
uniprot id: A0A8B7X1M4
uniprot id: A0A8B7X2A4
uniprot id: A0A8C5W8V8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:LOC105865927
gene id: 30608:LOC105865927
uniprot id: A0A8B7FNS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:FAM109B
gene id: 30608:FAM109B
uniprot id: A0A8B7ESI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Forms homodimers and heterodimers with PHETA. Interacts with OCRL and INPP5B.
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

30608:MLEC
gene id: 30608:MLEC
uniprot id: A0A8B7FSQ5
uniprot id: A0A8B7FTA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the malectin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:CSNK1G3
gene id: 30608:CSNK1G3
uniprot id: A0A8B7G292
uniprot id: A0A8B7XD98
uniprot id: A0A8B7XD99
uniprot id: A0A8B7XDA3
uniprot id: A0A8B7XF01
uniprot id: A0A8B7XFI9
uniprot id: A0A8C5XRJ6
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

30608:HINT1
gene id: 30608:HINT1
uniprot id: A0A8B7G5M4
names: Similarity
messages: Belongs to the HINT family.

30608:SLC13A3
gene id: 30608:SLC13A3
uniprot id: A0A8B7ETG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

30608:SLC6A13
gene id: 30608:SLC6A13
uniprot id: A0A8B7F798
uniprot id: A0A8B7F7A1
uniprot id: A0A8B7F7D7
uniprot id: A0A8B7F7I2
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A13 subfamily.
messages: Cell membrane
messages: Membrane

30608:EPHX1
gene id: 30608:EPHX1
uniprot id: A0A8C5XHX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

30608:SLC25A42
gene id: 30608:SLC25A42
uniprot id: A0A8B7WW84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:DHDH
gene id: 30608:DHDH
uniprot id: A0A8B7FM30
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

30608:LOC105870906
gene id: 30608:LOC105870906
uniprot id: A0A8B7GAY2
names: Function
messages: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.

30608:LOC105873263
gene id: 30608:LOC105873263
uniprot id: A0A8B7GKW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TMC5
gene id: 30608:TMC5
uniprot id: A0A8B7WNP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

30608:TBX20
gene id: 30608:TBX20
uniprot id: A0A8C5Y2R9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

30608:SPECC1L
gene id: 30608:SPECC1L
uniprot id: A0A8B7F9L0
uniprot id: A0A8B7F9L7
uniprot id: A0A8B7FA34
uniprot id: A0A8C5VPN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytospin-A family.
messages: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.
messages: May interact with both microtubules and actin cytoskeleton.
messages: cytoskeleton
messages: gap junction
messages: spindle

30608:PQLC1
gene id: 30608:PQLC1
uniprot id: A0A8B7WR78
names: Subcellular Location Annotation
messages: Membrane

30608:RAMP2
gene id: 30608:RAMP2
uniprot id: A0A8B7EU36
names: Similarity
messages: Belongs to the RAMP family.

30608:GPATCH11
gene id: 30608:GPATCH11
uniprot id: A0A8C5XXN8
names: Similarity
messages: Belongs to the GPATCH11 family.

30608:MND1
gene id: 30608:MND1
uniprot id: A0A8B7HN25
uniprot id: A0A8B7HN26
uniprot id: A0A8B7HN30
uniprot id: A0A8B7WKF6
uniprot id: A0A8B7WKH3
uniprot id: A0A8B7WL48
uniprot id: A0A8C5W8F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MND1 family.
messages: Nucleus
messages: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.

30608:CLCN5
gene id: 30608:CLCN5
uniprot id: A0A8B7FTH9
uniprot id: A0A8B7FU51
uniprot id: A0A8B7WYV5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-5/CLCN5 subfamily.
messages: Cell membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Interacts with NEDD4 and NEDD4L.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:METRNL
gene id: 30608:METRNL
uniprot id: A0A8B7H853
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the meteorin family.
messages: Secreted

30608:LMF1
gene id: 30608:LMF1
uniprot id: A0A8B7WNT7
uniprot id: A0A8B7WQ41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Membrane

30608:LOC109729613
gene id: 30608:LOC109729613
uniprot id: A0A8B7WPG2
names: Similarity
messages: Belongs to the Speedy/Ringo family.

30608:PARL
gene id: 30608:PARL
uniprot id: A0A8B7X2Y7
uniprot id: A0A8C5YKA2
names: Subcellular Location Annotation
messages: Membrane

30608:YIF1A
gene id: 30608:YIF1A
uniprot id: A0A8B7FUT0
uniprot id: A0A8B7FVN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

30608:LOC105869391
gene id: 30608:LOC105869391
uniprot id: A0A8B7G4Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

30608:LOC105860501
gene id: 30608:LOC105860501
uniprot id: A0A8B7EZ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

30608:GDF6
gene id: 30608:GDF6
uniprot id: A0A8B7GXF2
names: Similarity
messages: Belongs to the TGF-beta family.

30608:NR2F2
gene id: 30608:NR2F2
uniprot id: A0A8B7GBK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

30608:GLYATL3
gene id: 30608:GLYATL3
uniprot id: A0A8B7G3Z4
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

30608:SLC25A25
gene id: 30608:SLC25A25
uniprot id: A0A8B7GVI9
uniprot id: A0A8B7GVJ6
uniprot id: A0A8B7GVP7
uniprot id: A0A8B7GXC0
uniprot id: A0A8C5VT45
uniprot id: A0A8C5W957
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

30608:FABP2
gene id: 30608:FABP2
uniprot id: A0A8B7FMQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm
messages: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.

30608:LYNX1
gene id: 30608:LYNX1
uniprot id: A0A8B7HN27
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:LOC105869128
gene id: 30608:LOC105869128
uniprot id: A0A8C5UN50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

30608:CCDC65
gene id: 30608:CCDC65
uniprot id: A0A8C5VVL4
names: Subcellular Location Annotation
names: Subunit
messages: Component of the nexin-dynein regulatory complex (N-DRC).
messages: flagellum axoneme

30608:FCHO1
gene id: 30608:FCHO1
uniprot id: A0A8B7EAH6
uniprot id: A0A8B7WVZ9
uniprot id: A0A8B7WWA9
uniprot id: A0A8B7WWP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FCHO family.
messages: clathrin-coated pit

30608:AXIN2
gene id: 30608:AXIN2
uniprot id: A0A8B7F524
uniprot id: A0A8B7F534
uniprot id: A0A8C5YBM9
names: Subcellular Location Annotation
messages: Cytoplasm

30608:ZER1
gene id: 30608:ZER1
uniprot id: A0A8B7GVT1
uniprot id: A0A8B7GVT9
names: Similarity
messages: Belongs to the zyg-11 family.

30608:TNKS2
gene id: 30608:TNKS2
uniprot id: A0A8B7GET4
uniprot id: A0A8B7GEV4
uniprot id: A0A8B7GFP4
names: Similarity
messages: Belongs to the ARTD/PARP family.

30608:USP1
gene id: 30608:USP1
uniprot id: A0A8B7GI63
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

30608:PLCZ1
gene id: 30608:PLCZ1
uniprot id: A0A8B7HSK1
uniprot id: A0A8B7HSK9
uniprot id: A0A8B7HSM3
uniprot id: A0A8B7X618
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.
messages: perinuclear region

30608:SELL
gene id: 30608:SELL
uniprot id: A0A8B7HNQ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:NAP1L3
gene id: 30608:NAP1L3
uniprot id: A0A8B7FTR3
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

30608:MPG
gene id: 30608:MPG
uniprot id: A0A8B7EFD8
uniprot id: A0A8B7EFW5
uniprot id: A0A8C5W0F0
names: Function
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.
messages: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.

30608:SUCLA2
gene id: 30608:SUCLA2
uniprot id: A0A8B7FZF3
uniprot id: A0A8C5VYJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for ATP.
messages: Mitochondrion

30608:PEX10
gene id: 30608:PEX10
uniprot id: A0A8B7H665
names: Function
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.
messages: Somewhat implicated in the biogenesis of peroxisomes.

30608:TNXB
gene id: 30608:TNXB
uniprot id: A0A8B7ENK2
uniprot id: A0A8B7ENL3
uniprot id: A0A8B7ENQ8
uniprot id: A0A8B7EQ36
uniprot id: A0A8B7EQ41
uniprot id: A0A8B7EQQ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:DNASE1L1
gene id: 30608:DNASE1L1
uniprot id: A0A8C5VBD8
names: Similarity
messages: Belongs to the DNase I family.

30608:PRKAR1A
gene id: 30608:PRKAR1A
uniprot id: A0A8B7F5B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

30608:TIGD2
gene id: 30608:TIGD2
uniprot id: A0A8B7WXM5
names: Subcellular Location Annotation
messages: Nucleus

30608:ASB6
gene id: 30608:ASB6
uniprot id: A0A8B7GVY0
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

30608:SEMA3G
gene id: 30608:SEMA3G
uniprot id: A0A8B7GU71
uniprot id: A0A8C5VNR3
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:RPS27A
gene id: 30608:RPS27A
uniprot id: A0A8C5W9V5
names: Function
names: Similarity
names: Subunit
messages: Component of the 40S subunit of the ribosome.
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Ribosomal protein S27a is part of the 40S ribosomal subunit.

30608:ABCG5
gene id: 30608:ABCG5
uniprot id: A0A8B7FS34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

30608:SLIT3
gene id: 30608:SLIT3
uniprot id: A0A8B7HGX9
uniprot id: A0A8B7HHP5
uniprot id: A0A8B7HJK4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:UTP23
gene id: 30608:UTP23
uniprot id: A0A8C5VUX9
names: Subcellular Location Annotation
messages: nucleolus

30608:DYRK2
gene id: 30608:DYRK2
uniprot id: A0A8B7HK80
uniprot id: A0A8B7HLF4
uniprot id: A0A8C5VFU5
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

30608:LOC105864569
gene id: 30608:LOC105864569
uniprot id: A0A8B7FHN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:FUT11
gene id: 30608:FUT11
uniprot id: A0A8B7G123
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Membrane

30608:AURKA
gene id: 30608:AURKA
uniprot id: A0A8B7F7U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: centrosome

30608:GMDS
gene id: 30608:GMDS
uniprot id: A0A8B7GLN5
uniprot id: A0A8B7GLN8
uniprot id: A0A8B7GM01
uniprot id: A0A8B7GM07
uniprot id: A0A8B7GMY9
uniprot id: A0A8C5Y9V1
uniprot id: A0A8C5YDZ0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

30608:TRAPPC13
gene id: 30608:TRAPPC13
uniprot id: A0A8B7HP52
uniprot id: A0A8B7HQT3
uniprot id: A0A8B7XCP3
uniprot id: A0A8B7XEY4
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

30608:DACT3
gene id: 30608:DACT3
uniprot id: A0A8B7G4Z6
names: Similarity
messages: Belongs to the dapper family.

30608:HDHD2
gene id: 30608:HDHD2
uniprot id: A0A8B7EZE2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

30608:EFHC1
gene id: 30608:EFHC1
uniprot id: A0A8B7G2L3
names: Subcellular Location Annotation
messages: cilium axoneme

30608:LOC105873827
gene id: 30608:LOC105873827
uniprot id: A0A8B7WUX7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:HTR2B
gene id: 30608:HTR2B
uniprot id: A0A8B7F9W4
uniprot id: A0A8B7FA02
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts (via C-terminus) with MPDZ.
messages: Membrane
messages: synaptosome

30608:CMC1
gene id: 30608:CMC1
uniprot id: A0A8B7HY99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

30608:LOC109730720
gene id: 30608:LOC109730720
uniprot id: A0A8B7X3X6
names: Subcellular Location Annotation
messages: Membrane

30608:CRYBA1
gene id: 30608:CRYBA1
uniprot id: A0A8B7EPE7
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

30608:CMTM4
gene id: 30608:CMTM4
uniprot id: A0A8B7ES98
names: Subcellular Location Annotation
messages: Membrane

30608:EPB41L5
gene id: 30608:EPB41L5
uniprot id: A0A8B7FAR7
uniprot id: A0A8B7FAS1
uniprot id: A0A8B7X9E4
uniprot id: A0A8C5VQF5
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Photoreceptor inner segment
messages: Plays a role in the formation and organization of tight junctions during the establishment of polarity in epithelial cells.

30608:FGF1
gene id: 30608:FGF1
uniprot id: A0A8B7F8K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

30608:HMGCS2
gene id: 30608:HMGCS2
uniprot id: A0A8C5YCQ0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

30608:IRX5
gene id: 30608:IRX5
uniprot id: A0A8B7GX25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

30608:MLNR
gene id: 30608:MLNR
uniprot id: A0A8B7EE64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105867143
gene id: 30608:LOC105867143
uniprot id: A0A8B7FTC5
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:COPZ1
gene id: 30608:COPZ1
uniprot id: A0A8B7GBG0
uniprot id: A0A8B7GC07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

30608:DSC2
gene id: 30608:DSC2
uniprot id: A0A8B7WRI1
uniprot id: A0A8C5UP16
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

30608:LOC105861769
gene id: 30608:LOC105861769
uniprot id: A0A8B7F5I1
uniprot id: A0A8B7F5I6
names: Similarity
messages: Belongs to the CLCR family.

30608:MTMR6
gene id: 30608:MTMR6
uniprot id: A0A8B7EFQ4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

30608:CFL2
gene id: 30608:CFL2
uniprot id: A0A8B7EC78
uniprot id: A0A8C5VLK7
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

30608:LDHB
gene id: 30608:LDHB
uniprot id: A0A8B7HSI5
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

30608:DDX55
gene id: 30608:DDX55
uniprot id: A0A8B7WTN0
names: Similarity
messages: Belongs to the DEAD box helicase family.

30608:CTNND2
gene id: 30608:CTNND2
uniprot id: A0A8B7I4H8
uniprot id: A0A8B7I4K1
uniprot id: A0A8B7I6I5
uniprot id: A0A8B7I7K9
uniprot id: A0A8B7XCR9
names: Similarity
messages: Belongs to the beta-catenin family.

30608:LOC105876114
gene id: 30608:LOC105876114
uniprot id: A0A8B7GZM1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

30608:LIN28B
gene id: 30608:LIN28B
uniprot id: A0A8B7FJF8
uniprot id: A0A8C5Y995
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-28 family.
messages: nucleolus

30608:PPARG
gene id: 30608:PPARG
uniprot id: A0A8B7HS26
uniprot id: A0A8B7HS35
uniprot id: A0A8B7HU23
uniprot id: A0A8B7WVB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Cytoplasm
messages: Heterodimer with other nuclear receptors.
messages: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. May play a role in the regulation of circadian rhythm.
messages: Nucleus

30608:EML6
gene id: 30608:EML6
uniprot id: A0A8B7H9B1
uniprot id: A0A8B7H9B9
uniprot id: A0A8B7H9C6
uniprot id: A0A8B7HC33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
messages: cytoskeleton

30608:BARHL2
gene id: 30608:BARHL2
uniprot id: A0A8C5W6Y8
names: Subcellular Location Annotation
messages: Nucleus

30608:RGMB
gene id: 30608:RGMB
uniprot id: A0A8B7GZG2
uniprot id: A0A8C5Y109
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

30608:NR1H2
gene id: 30608:NR1H2
uniprot id: A0A8B7FLU4
uniprot id: A0A8C5W5K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

30608:PRM1
gene id: 30608:PRM1
uniprot id: A0A8B7HQQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protamine P1 family.
messages: Chromosome
messages: Nucleus
messages: Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.

30608:CTU1
gene id: 30608:CTU1
uniprot id: A0A8B7FLY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3. May form a heterodimer with CTU2/NCS2.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

30608:VPS13C
gene id: 30608:VPS13C
uniprot id: A0A8B7X1S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS13 family.
messages: Lipid droplet

30608:SAP130
gene id: 30608:SAP130
uniprot id: A0A8B7FBB9
uniprot id: A0A8B7FC07
uniprot id: A0A8B7X9G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

30608:LOC105884162
gene id: 30608:LOC105884162
uniprot id: A0A8B7HYL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:EIF3L
gene id: 30608:EIF3L
uniprot id: A0A8B7EQE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with RRN3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm

30608:GORASP2
gene id: 30608:GORASP2
uniprot id: A0A8B7HJ35
names: Similarity
messages: Belongs to the GORASP family.

30608:UBALD2
gene id: 30608:UBALD2
uniprot id: A0A8B7HBY6
uniprot id: A0A8C5VKS1
names: Similarity
messages: Belongs to the UBALD family.

30608:MON1B
gene id: 30608:MON1B
uniprot id: A0A8B7GWT1
uniprot id: A0A8B7GYL5
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

30608:FGFR1
gene id: 30608:FGFR1
uniprot id: A0A8B7G7W5
uniprot id: A0A8B7G830
uniprot id: A0A8B7G8K6
uniprot id: A0A8B7G8Z9
uniprot id: A0A8B7G902
uniprot id: A0A8B7WRV5
uniprot id: A0A8B7WRW6
uniprot id: A0A8C5Y745
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Membrane
messages: Nucleus
messages: Vesicle
messages: cytosol

30608:PABPC1L
gene id: 30608:PABPC1L
uniprot id: A0A8B7HFU7
uniprot id: A0A8B7HFX2
uniprot id: A0A8B7HGI1
uniprot id: A0A8B7HIG9
uniprot id: A0A8B7HII3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

30608:PSMD9
gene id: 30608:PSMD9
uniprot id: A0A8B7WU42
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

30608:LOC105876302
gene id: 30608:LOC105876302
uniprot id: A0A8B7H076
names: Subcellular Location Annotation
messages: Nucleus

30608:CDH5
gene id: 30608:CDH5
uniprot id: A0A8B7ESJ7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell junction
messages: Cell membrane
messages: Membrane

30608:ATG9B
gene id: 30608:ATG9B
uniprot id: A0A8B7HU72
uniprot id: A0A8B7HU74
uniprot id: A0A8B7HWA4
uniprot id: A0A8B7XBR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

30608:OLA1
gene id: 30608:OLA1
uniprot id: A0A8B7FL58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.
messages: Nucleus
messages: nucleolus

30608:SORCS3
gene id: 30608:SORCS3
uniprot id: A0A8B7GSF5
uniprot id: A0A8B7GSP5
uniprot id: A0A8C6ECX4
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

30608:ECH1
gene id: 30608:ECH1
uniprot id: A0A8B7H1W1
uniprot id: A0A8B7H3Y3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

30608:XPA
gene id: 30608:XPA
uniprot id: A0A8C5V6X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

30608:SOST
gene id: 30608:SOST
uniprot id: A0A8B7HXN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the sclerostin family.
messages: Interacts with LRP4 (via the extracellular domain); the interaction facilitates the inhibition of Wnt signaling. Interacts with LRP5 (via the first two YWTD-EGF repeat domains); the interaction inhibits Wnt-mediated signaling. Interacts with LRP6.
messages: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

30608:PTCD2
gene id: 30608:PTCD2
uniprot id: A0A8B7HNP0
uniprot id: A0A8B7HPQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTCD2 family.
messages: Mitochondrion

30608:SFT2D1
gene id: 30608:SFT2D1
uniprot id: A0A8C5WBB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

30608:ADAMTS6
gene id: 30608:ADAMTS6
uniprot id: A0A8B7HP45
uniprot id: A0A8B7HP46
uniprot id: A0A8B7HRI5
uniprot id: A0A8B7XCP8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:HESX1
gene id: 30608:HESX1
uniprot id: A0A8C5Y950
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANF homeobox family.
messages: Nucleus

30608:ELOVL6
gene id: 30608:ELOVL6
uniprot id: A0A8B7GFX2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

30608:MTRF1L
gene id: 30608:MTRF1L
uniprot id: A0A8B7F6Y9
uniprot id: A0A8B7F6Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

30608:LOC105879037
gene id: 30608:LOC105879037
uniprot id: A0A8B7WXC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

30608:CLDN2
gene id: 30608:CLDN2
uniprot id: A0A8B7FE47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

30608:AU129 gp04
gene id: 30608:AU129_gp04
uniprot id: A0A0U2I1K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

30608:KIAA0922
gene id: 30608:KIAA0922
uniprot id: A0A8B7HPL5
uniprot id: A0A8B7WKF0
uniprot id: A0A8B7WKG8
uniprot id: A0A8B7WKI7
uniprot id: A0A8B7WL43
names: Similarity
messages: Belongs to the TMEM131 family.

30608:FOXC2
gene id: 30608:FOXC2
uniprot id: A0A8B7GD12
names: Subcellular Location Annotation
messages: Nucleus

30608:SLC18B1
gene id: 30608:SLC18B1
uniprot id: A0A8B7ECL4
uniprot id: A0A8C5VHA5
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105867538
gene id: 30608:LOC105867538
uniprot id: A0A8B7FV90
uniprot id: A0A8B7FW78
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:PPM1L
gene id: 30608:PPM1L
uniprot id: A0A8C5YFY2
names: Similarity
messages: Belongs to the PP2C family.

30608:MXRA8
gene id: 30608:MXRA8
uniprot id: A0A8B7H8E2
uniprot id: A0A8C5V6M1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:RLN3
gene id: 30608:RLN3
uniprot id: A0A8B7I4P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

30608:REXO4
gene id: 30608:REXO4
uniprot id: A0A8C5VZB6
names: Similarity
messages: Belongs to the REXO4 family.

30608:UBE2D2
gene id: 30608:UBE2D2
uniprot id: A0A8B7WR13
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:TMEM27
gene id: 30608:TMEM27
uniprot id: A0A8B7HSL8
names: Subcellular Location Annotation
messages: Membrane

30608:FOXF2
gene id: 30608:FOXF2
uniprot id: A0A8B7GLP8
names: Subcellular Location Annotation
messages: Nucleus

30608:DNA2
gene id: 30608:DNA2
uniprot id: A0A8B7G746
uniprot id: A0A8B7G889
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Mitochondrion
messages: Nucleus

30608:IL4R
gene id: 30608:IL4R
uniprot id: A0A8B7HEX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Membrane
messages: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

30608:MOK
gene id: 30608:MOK
uniprot id: A0A8B7F226
uniprot id: A0A8C6EKE3
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:EFNA4
gene id: 30608:EFNA4
uniprot id: A0A8B7GLD6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:LOC105875481
gene id: 30608:LOC105875481
uniprot id: A0A8B7GWU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

30608:PMM2
gene id: 30608:PMM2
uniprot id: A0A8B7HS65
uniprot id: A0A8B7HS91
uniprot id: A0A8B7HU63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

30608:TRPV4
gene id: 30608:TRPV4
uniprot id: A0A8B7WTE5
uniprot id: A0A8B7WTK6
uniprot id: A0A8B7WUU5
names: Subcellular Location Annotation
messages: Membrane

30608:FUT8
gene id: 30608:FUT8
uniprot id: A0A8B7H947
uniprot id: A0A8B7H952
uniprot id: A0A8B7H954
uniprot id: A0A8B7H955
uniprot id: A0A8B7X208
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 23 family.
messages: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
messages: Golgi stack membrane
messages: Membrane

30608:GLRX
gene id: 30608:GLRX
uniprot id: A0A8B7XFE8
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

30608:NRXN3
gene id: 30608:NRXN3
uniprot id: A0A8B7FT21
uniprot id: A0A8B7FT26
uniprot id: A0A8B7FT33
uniprot id: A0A8B7FT37
uniprot id: A0A8B7FT39
uniprot id: A0A8B7FT42
uniprot id: A0A8B7FT44
uniprot id: A0A8B7FT47
uniprot id: A0A8B7FT51
uniprot id: A0A8B7FT55
uniprot id: A0A8B7FT68
uniprot id: A0A8B7FT73
uniprot id: A0A8B7FT79
uniprot id: A0A8B7FT85
uniprot id: A0A8B7FT90
uniprot id: A0A8B7FTT1
uniprot id: A0A8B7FTT6
uniprot id: A0A8B7FTU4
uniprot id: A0A8B7FTU9
uniprot id: A0A8B7FTV5
uniprot id: A0A8B7FU25
uniprot id: A0A8B7FU30
uniprot id: A0A8B7FU34
uniprot id: A0A8B7FU43
uniprot id: A0A8B7X1X4
uniprot id: A0A8B7X1X9
uniprot id: A0A8B7X1Y5
uniprot id: A0A8B7X2H9
uniprot id: A0A8B7X378
uniprot id: A0A8B7X3P1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:ANAPC16
gene id: 30608:ANAPC16
uniprot id: A0A8B7G6Y6
uniprot id: A0A8C5YDY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

30608:HMX2
gene id: 30608:HMX2
uniprot id: A0A8B7HHQ3
names: Subcellular Location Annotation
messages: Nucleus

30608:EPN1
gene id: 30608:EPN1
uniprot id: A0A8B7FBY6
uniprot id: A0A8B7FBY9
uniprot id: A0A8B7FBZ7
uniprot id: A0A8B7FC55
uniprot id: A0A8B7FCM4
names: Similarity
messages: Belongs to the epsin family.

30608:CARMIL1
gene id: 30608:CARMIL1
uniprot id: A0A8B7EP32
uniprot id: A0A8B7EP37
uniprot id: A0A8B7EP54
uniprot id: A0A8B7EP64
uniprot id: A0A8B7EQP4
uniprot id: A0A8B7ERA6
uniprot id: A0A8B7ERB1
uniprot id: A0A8C5URK5
uniprot id: A0A8C5YI66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

30608:TSPAN16
gene id: 30608:TSPAN16
uniprot id: A0A8C5YA15
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:FAM206A
gene id: 30608:FAM206A
uniprot id: A0A8C6EKK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABITRAM family.
messages: growth cone
messages: lamellipodium

30608:TATDN1
gene id: 30608:TATDN1
uniprot id: A0A8B7HZF0
uniprot id: A0A8B7I1J0
uniprot id: A0A8B7XA12
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

30608:LOC105878641
gene id: 30608:LOC105878641
uniprot id: A0A8C5V176
names: Similarity
messages: Belongs to the peptidase A1 family.

30608:ARF3
gene id: 30608:ARF3
uniprot id: A0A8C5XTH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

30608:MAPRE3
gene id: 30608:MAPRE3
uniprot id: A0A8B7HZF5
uniprot id: A0A8C5V5M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

30608:UFC1
gene id: 30608:UFC1
uniprot id: A0A8C5VDF3
names: Function
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
messages: E1-like enzyme which specifically catalyzes the second step in ufmylation. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

30608:LOC105883081
gene id: 30608:LOC105883081
uniprot id: A0A8B7HTN9
uniprot id: A0A8B7HTP6
uniprot id: A0A8B7HTQ3
uniprot id: A0A8B7HVX5
uniprot id: A0A8B7WXJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

30608:ZDHHC3
gene id: 30608:ZDHHC3
uniprot id: A0A8B7GRB8
uniprot id: A0A8B7GRC3
uniprot id: A0A8B7GRD0
uniprot id: A0A8B7GRL7
uniprot id: A0A8B7GT06
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

30608:AU129 gp06
gene id: 30608:AU129_gp06
uniprot id: Q94NN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

30608:SLC5A12
gene id: 30608:SLC5A12
uniprot id: A0A8B7EXJ9
uniprot id: A0A8B7EZF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

30608:LOC105875314
gene id: 30608:LOC105875314
uniprot id: A0A8B7GW16
names: Subcellular Location Annotation
messages: Membrane

30608:PPY
gene id: 30608:PPY
uniprot id: A0A8B7HVK9
uniprot id: A0A8B7HXR9
uniprot id: A0A8B7HXW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions.
messages: Secreted

30608:UBN2
gene id: 30608:UBN2
uniprot id: A0A8B7GKD9
uniprot id: A0A8B7GKE5
uniprot id: A0A8B7GL14
uniprot id: A0A8C5Y010
names: Similarity
messages: Belongs to the ubinuclein family.

30608:FBLN1
gene id: 30608:FBLN1
uniprot id: A0A8C5V5U5
uniprot id: A0A8C5XWX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:EMC10
gene id: 30608:EMC10
uniprot id: A0A8B7FLX4
uniprot id: A0A8B7WUR4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC10 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

30608:LOC105869723
gene id: 30608:LOC105869723
uniprot id: A0A8B7G4U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PLK4
gene id: 30608:PLK4
uniprot id: A0A8B7I6J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
messages: Cleavage furrow
messages: centriole

30608:LOC105860793
gene id: 30608:LOC105860793
uniprot id: A0A8B7F0H0
uniprot id: A0A8B7F270
uniprot id: A0A8B7F2S4
names: Similarity
messages: Belongs to the paralemmin family.

30608:LOC105861305
gene id: 30608:LOC105861305
uniprot id: A0A8B7F2M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CNP
gene id: 30608:CNP
uniprot id: A0A8B7GEQ4
uniprot id: A0A8B7GEQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2H phosphoesterase superfamily. CNPase family.
messages: Exists as monomers and homodimers.
messages: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.
messages: Melanosome
messages: Membrane

30608:FHL5
gene id: 30608:FHL5
uniprot id: A0A8B7GPE3
names: Function
names: Subcellular Location Annotation
messages: May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner.
messages: Nucleus

30608:UCN3
gene id: 30608:UCN3
uniprot id: A0A8B7EP23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

30608:TMEM255B
gene id: 30608:TMEM255B
uniprot id: A0A8B7XDG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

30608:CPQ
gene id: 30608:CPQ
uniprot id: A0A8B7G5C9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. The monomeric form is inactive while the homodimer is active.
messages: Lysosome
messages: Secreted

30608:PSMB4
gene id: 30608:PSMB4
uniprot id: A0A8B7GJE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

30608:LOC105865908
gene id: 30608:LOC105865908
uniprot id: A0A8B7FPQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105864533
gene id: 30608:LOC105864533
uniprot id: A0A8B7FHI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:GDNF
gene id: 30608:GDNF
uniprot id: A0A8B7EC35
uniprot id: A0A8B7EES1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

30608:PKN3
gene id: 30608:PKN3
uniprot id: A0A8B7XBD8
uniprot id: A0A8C5V5N7
uniprot id: A0A8C5XIS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

30608:TOE1
gene id: 30608:TOE1
uniprot id: A0A8B7H4X9
uniprot id: A0A8B7H4Y1
names: Similarity
messages: Belongs to the CAF1 family.

30608:POLR3C
gene id: 30608:POLR3C
uniprot id: A0A8B7G5B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

30608:TIMP3
gene id: 30608:TIMP3
uniprot id: A0A8C5YCL3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: Interacts with EFEMP1.
messages: extracellular matrix

30608:HOXD1
gene id: 30608:HOXD1
uniprot id: A0A8C5XSY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Labial subfamily.
messages: Nucleus

30608:FUS
gene id: 30608:FUS
uniprot id: A0A8B7GAM2
uniprot id: A0A8B7GAM7
uniprot id: A0A8B7GB24
uniprot id: A0A8B7GB87
uniprot id: A0A8B7GBP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

30608:GRIA3
gene id: 30608:GRIA3
uniprot id: A0A8B7F279
uniprot id: A0A8C5YA18
uniprot id: A0A8C5YC12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

30608:FAM120B
gene id: 30608:FAM120B
uniprot id: A0A8B7HKH2
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

30608:LOC105872331
gene id: 30608:LOC105872331
uniprot id: A0A8B7GG39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

30608:GPRIN2
gene id: 30608:GPRIN2
uniprot id: A0A8B7HZ08
uniprot id: A0A8B7HZ13
names: Function
messages: May be involved in neurite outgrowth.

30608:LOC105881968
gene id: 30608:LOC105881968
uniprot id: A0A8B7HNY9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

30608:SLC37A2
gene id: 30608:SLC37A2
uniprot id: A0A8B7FHJ4
uniprot id: A0A8B7FHM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.
messages: Membrane

30608:RBFOX2
gene id: 30608:RBFOX2
uniprot id: A0A8B7HWJ7
uniprot id: A0A8B7HWK0
uniprot id: A0A8B7HWK3
uniprot id: A0A8B7HWK5
uniprot id: A0A8B7HWK8
uniprot id: A0A8B7HWL2
uniprot id: A0A8B7HWL3
uniprot id: A0A8B7HWL6
uniprot id: A0A8B7HWL7
uniprot id: A0A8B7HWM3
uniprot id: A0A8B7HWM5
uniprot id: A0A8B7HYN8
uniprot id: A0A8B7HYP4
uniprot id: A0A8B7HYP9
uniprot id: A0A8B7HYQ4
uniprot id: A0A8B7HYQ8
uniprot id: A0A8B7HZ15
uniprot id: A0A8B7HZ20
uniprot id: A0A8B7HZ25
uniprot id: A0A8B7HZ30
uniprot id: A0A8B7HZ35
uniprot id: A0A8B7X6E5
uniprot id: A0A8B7X851
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

30608:FAM192A
gene id: 30608:FAM192A
uniprot id: A0A8B7FQJ3
uniprot id: A0A8B7FQN8
uniprot id: A0A8B7FQQ1
uniprot id: A0A8B7FR25
uniprot id: A0A8C5VT77
names: Subcellular Location Annotation
messages: Nucleus

30608:GATC
gene id: 30608:GATC
uniprot id: A0A8C5XCX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

30608:LOC105867403
gene id: 30608:LOC105867403
uniprot id: A0A8B7FUJ6
names: Subcellular Location Annotation
messages: Cytoplasm

30608:STK38L
gene id: 30608:STK38L
uniprot id: A0A8B7EK74
uniprot id: A0A8C5Y5A5
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:PRR15
gene id: 30608:PRR15
uniprot id: A0A8B7EAN3
names: Similarity
messages: Belongs to the PRR15 family.

30608:ETV2
gene id: 30608:ETV2
uniprot id: A0A8B7H2N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:LOC105877214
gene id: 30608:LOC105877214
uniprot id: A0A8B7H690
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

30608:CXCR5
gene id: 30608:CXCR5
uniprot id: A0A8B7GZB7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:PKD2
gene id: 30608:PKD2
uniprot id: A0A8B7WZ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Cell membrane
messages: Membrane
messages: cilium membrane

30608:KRT19
gene id: 30608:KRT19
uniprot id: A0A8C5W268
names: Similarity
messages: Belongs to the intermediate filament family.

30608:LOC105861288
gene id: 30608:LOC105861288
uniprot id: A0A8B7F2K3
names: Subcellular Location Annotation
messages: Membrane

30608:PTH2R
gene id: 30608:PTH2R
uniprot id: A0A8B7FGK4
uniprot id: A0A8B7FGL6
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105884123
gene id: 30608:LOC105884123
uniprot id: A0A8B7HYH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:VAT1L
gene id: 30608:VAT1L
uniprot id: A0A8B7F9Q9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

30608:DLGAP1
gene id: 30608:DLGAP1
uniprot id: A0A8B7F0R2
uniprot id: A0A8B7F0R6
uniprot id: A0A8B7F0R7
uniprot id: A0A8B7F0R9
uniprot id: A0A8B7F0S1
uniprot id: A0A8B7F0S2
uniprot id: A0A8B7F0S3
uniprot id: A0A8B7F0S5
uniprot id: A0A8B7F2I0
uniprot id: A0A8B7F2I5
uniprot id: A0A8B7F2J0
uniprot id: A0A8C5XK53
names: Similarity
messages: Belongs to the SAPAP family.

30608:COMP
gene id: 30608:COMP
uniprot id: A0A8B7WW71
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105881930
gene id: 30608:LOC105881930
uniprot id: A0A8B7HQD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105883464
gene id: 30608:LOC105883464
uniprot id: A0A8B7HXH6
names: Subcellular Location Annotation
messages: Membrane

30608:ATP6V0B
gene id: 30608:ATP6V0B
uniprot id: A0A8B7H4Q2
uniprot id: A0A8B7H4Q3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: clathrin-coated vesicle membrane

30608:MED17
gene id: 30608:MED17
uniprot id: A0A8B7EK77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

30608:TCAF1
gene id: 30608:TCAF1
uniprot id: A0A8B7GLX1
uniprot id: A0A8C5VU97
names: Similarity
messages: Belongs to the TCAF family.

30608:LOC105857576
gene id: 30608:LOC105857576
uniprot id: A0A8B7EL01
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

30608:ADGRL1
gene id: 30608:ADGRL1
uniprot id: A0A8B7FWT3
uniprot id: A0A8B7FWZ8
uniprot id: A0A8B7FXR4
names: Subcellular Location Annotation
messages: Membrane

30608:HK3
gene id: 30608:HK3
uniprot id: A0A8B7HZP4
uniprot id: A0A8C5ULP2
names: Similarity
messages: Belongs to the hexokinase family.

30608:NUCB2
gene id: 30608:NUCB2
uniprot id: A0A8B7HIX1
uniprot id: A0A8C5XQ13
names: Similarity
messages: Belongs to the nucleobindin family.

30608:LOC105878632
gene id: 30608:LOC105878632
uniprot id: A0A8B7HAK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Binds with high affinity to IPO4. Interacts with DDIT3.
messages: Cytoplasm
messages: May play a role during erythropoiesis through regulation of transcription factor DDIT3.
messages: Nucleus

30608:MANBAL
gene id: 30608:MANBAL
uniprot id: A0A8B7FPV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0239 family.
messages: Membrane

30608:LOC109731194
gene id: 30608:LOC109731194
uniprot id: A0A8B7XBG0
names: Similarity
messages: Belongs to the CD225/Dispanin family.

30608:LOC105875326
gene id: 30608:LOC105875326
uniprot id: A0A8B7GXU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:FOXL2
gene id: 30608:FOXL2
uniprot id: A0A8C5YHS0
names: Subcellular Location Annotation
messages: Nucleus

30608:DEUP1
gene id: 30608:DEUP1
uniprot id: A0A8B7EK63
uniprot id: A0A8B7EK68
uniprot id: A0A8B7EKH5
uniprot id: A0A8B7EKI0
uniprot id: A0A8B7ELE7
uniprot id: A0A8B7ELF4
uniprot id: A0A8B7EMI2
uniprot id: A0A8B7EMI7
uniprot id: A0A8B7X3D8
uniprot id: A0A8C5VDJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP63 family.
messages: Cytoplasm

30608:GOLPH3
gene id: 30608:GOLPH3
uniprot id: A0A8B7EH64
uniprot id: A0A8C5VHN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

30608:LOC105875313
gene id: 30608:LOC105875313
uniprot id: A0A8B7GXU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:RTCA
gene id: 30608:RTCA
uniprot id: A0A8B7F843
uniprot id: A0A8C5UWE5
names: Function
names: Similarity
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.

30608:SLC29A3
gene id: 30608:SLC29A3
uniprot id: A0A8B7G7J9
uniprot id: A0A8C5XK74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

30608:P4HB
gene id: 30608:P4HB
uniprot id: A0A8B7I4H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

30608:RIOK3
gene id: 30608:RIOK3
uniprot id: A0A8C5VJQ9
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
messages: Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses.

30608:LOC105884179
gene id: 30608:LOC105884179
uniprot id: A0A8B7I1A9
names: Similarity
messages: Belongs to the BEX family.

30608:JMJD1C
gene id: 30608:JMJD1C
uniprot id: A0A8B7G787
uniprot id: A0A8B7G794
uniprot id: A0A8B7G7E2
uniprot id: A0A8B7G7X0
uniprot id: A0A8B7G7X7
uniprot id: A0A8B7G8C9
names: Subcellular Location Annotation
messages: Nucleus

30608:CERS4
gene id: 30608:CERS4
uniprot id: A0A8B7WWG5
uniprot id: A0A8C5XSS1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

30608:OSM
gene id: 30608:OSM
uniprot id: A0A8C5XFG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LIF/OSM family.
messages: Secreted

30608:ZC3H14
gene id: 30608:ZC3H14
uniprot id: A0A8B7X263
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZC3H14 family.
messages: Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
messages: Nucleus speckle

30608:SLC4A2
gene id: 30608:SLC4A2
uniprot id: A0A8B7HU58
uniprot id: A0A8B7HW92
uniprot id: A0A8C5VPZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane
messages: Plasma membrane anion exchange protein of wide distribution.

30608:NEUROD4
gene id: 30608:NEUROD4
uniprot id: A0A8B7FMN6
names: Subcellular Location Annotation
messages: Nucleus

30608:TSR3
gene id: 30608:TSR3
uniprot id: A0A8C6EL13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SIRT4
gene id: 30608:SIRT4
uniprot id: A0A8B7FSD7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: According to some authors, ADP-ribosyltransferase activity of sirtuins may be an inefficient side reaction of the deacetylase activity and may not be physiologically relevant.
messages: Acts as NAD-dependent protein lipoamidase, biotinylase, deacetylase and ADP-ribosyl transferase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitochondrial glutamine metabolism by mediating mono ADP-ribosylation of GLUD1: expressed in response to DNA damage and negatively regulates anaplerosis by inhibiting GLUD1, leading to block metabolism of glutamine into tricarboxylic acid cycle and promoting cell cycle arrest. In response to mTORC1 signal, SIRT4 expression is repressed, promoting anaplerosis and cell proliferation. Acts as a tumor suppressor. Also acts as a NAD-dependent protein deacetylase: mediates deacetylation of 'Lys-471' of MLYCD, inhibiting its activity, thereby acting as a regulator of lipid homeostasis. Does not seem to deacetylate PC. Controls fatty acid oxidation by inhibiting PPARA transcriptional activation. Impairs SIRT1-PPARA interaction probably through the regulation of NAD(+) levels. Down-regulates insulin secretion.
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Interacts with GLUD1, IDE and SLC25A5. Interacts with DLAT and PDHX.
messages: Mitochondrion matrix

30608:ALK
gene id: 30608:ALK
uniprot id: A0A8B7HZS5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.

30608:KAT5
gene id: 30608:KAT5
uniprot id: A0A8B7HA30
uniprot id: A0A8B7HA32
uniprot id: A0A8B7HA36
uniprot id: A0A8B7HA37
uniprot id: A0A8C5UZE3
uniprot id: A0A8C5VUC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

30608:LOC109730006
gene id: 30608:LOC109730006
uniprot id: A0A8B7WW89
names: Subcellular Location Annotation
messages: Nucleus

30608:LOXL2
gene id: 30608:LOXL2
uniprot id: A0A8B7EJE5
uniprot id: A0A8B7EJR4
uniprot id: A0A8B7WSV3
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

30608:LOC105884287
gene id: 30608:LOC105884287
uniprot id: A0A8B7HZ19
uniprot id: A0A8B7I133
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:DSG2
gene id: 30608:DSG2
uniprot id: A0A8B7HKI6
uniprot id: A0A8C5VUK2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: desmosome

30608:PLA2G1B
gene id: 30608:PLA2G1B
uniprot id: A0A8B7FTQ5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

30608:TLR10
gene id: 30608:TLR10
uniprot id: A0A8B7FL54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

30608:PROS1
gene id: 30608:PROS1
uniprot id: A0A8B7WZP9
uniprot id: A0A8C5XDQ2
names: Caution
names: Function
messages: Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:STXBP3
gene id: 30608:STXBP3
uniprot id: A0A8C5XQ70
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

30608:ENAH
gene id: 30608:ENAH
uniprot id: A0A8B7FEL2
uniprot id: A0A8B7FEL7
uniprot id: A0A8B7FEM8
uniprot id: A0A8B7FEN2
uniprot id: A0A8B7FEN5
uniprot id: A0A8B7FEP1
uniprot id: A0A8B7FEP5
uniprot id: A0A8B7FEV1
uniprot id: A0A8B7FEV6
uniprot id: A0A8B7FEW1
uniprot id: A0A8B7FFM3
uniprot id: A0A8B7FFM8
uniprot id: A0A8B7FFN3
uniprot id: A0A8C5VSF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: cytoskeleton

30608:LOC105862115
gene id: 30608:LOC105862115
uniprot id: A0A8B7F6Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CCNL2
gene id: 30608:CCNL2
uniprot id: A0A8B7H605
uniprot id: A0A8C5V2F3
uniprot id: A0A8C5VKN0
names: Similarity
messages: Belongs to the cyclin family.

30608:CHIA
gene id: 30608:CHIA
uniprot id: A0A8B7FFK8
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

30608:LOC105875511
gene id: 30608:LOC105875511
uniprot id: A0A8B7X0A0
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

30608:TMEM263
gene id: 30608:TMEM263
uniprot id: A0A8B7X8G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

30608:TMC7
gene id: 30608:TMC7
uniprot id: A0A8B7EB23
uniprot id: A0A8B7EBE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

30608:ACSL1
gene id: 30608:ACSL1
uniprot id: A0A8B7HR91
uniprot id: A0A8B7HR97
uniprot id: A0A8B7HTK9
uniprot id: A0A8C5W8Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane

30608:DYNLRB1
gene id: 30608:DYNLRB1
uniprot id: A0A8B7FMT0
uniprot id: A0A8B7WPV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer.
messages: cytoskeleton

30608:EFNB2
gene id: 30608:EFNB2
uniprot id: A0A8C5VUC8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:UXS1
gene id: 30608:UXS1
uniprot id: A0A8B7EF13
uniprot id: A0A8B7EHK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

30608:CADM1
gene id: 30608:CADM1
uniprot id: A0A8B7F6M0
uniprot id: A0A8B7F6M3
uniprot id: A0A8B7F6M8
uniprot id: A0A8B7F6P9
uniprot id: A0A8B7F6T3
uniprot id: A0A8C5W2X2
names: Similarity
messages: Belongs to the nectin family.

30608:NME6
gene id: 30608:NME6
uniprot id: A0A8B7GT97
uniprot id: A0A8B7GV13
names: Similarity
messages: Belongs to the NDK family.

30608:VARS2
gene id: 30608:VARS2
uniprot id: A0A8B7X705
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

30608:POLR3A
gene id: 30608:POLR3A
uniprot id: A0A8B7G784
uniprot id: A0A8C5XC92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

30608:MRPL44
gene id: 30608:MRPL44
uniprot id: A0A8B7G335
uniprot id: A0A8B7G4I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.
messages: Mitochondrion

30608:TLCD2
gene id: 30608:TLCD2
uniprot id: A0A8B7EPI7
names: Subcellular Location Annotation
messages: Membrane

30608:RTBDN
gene id: 30608:RTBDN
uniprot id: A0A8B7I4X3
uniprot id: A0A8B7I821
names: Similarity
messages: Belongs to the folate receptor family.

30608:LOC105870101
gene id: 30608:LOC105870101
uniprot id: A0A8B7X552
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

30608:LOC105874980
gene id: 30608:LOC105874980
uniprot id: A0A8C5VC28
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

30608:DCTPP1
gene id: 30608:DCTPP1
uniprot id: A0A8C5W411
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homotetramer.
messages: Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.
messages: cytosol

30608:RPS21
gene id: 30608:RPS21
uniprot id: A0A8C5Y0W1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

30608:TAS2R5
gene id: 30608:TAS2R5
uniprot id: A0A8B7GL88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

30608:TRAPPC3
gene id: 30608:TRAPPC3
uniprot id: A0A8B7GE55
uniprot id: A0A8C5W7M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

30608:AP1S3
gene id: 30608:AP1S3
uniprot id: A0A8B7G336
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

30608:LOC105874841
gene id: 30608:LOC105874841
uniprot id: A0A8B7X2Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

30608:MRPL34
gene id: 30608:MRPL34
uniprot id: A0A8B7FQ58
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

30608:LOC105862594
gene id: 30608:LOC105862594
uniprot id: A0A8B7WRJ8
uniprot id: A0A8B7WRK6
uniprot id: A0A8B7WRL0
uniprot id: A0A8B7WRL8
uniprot id: A0A8B7WT21
uniprot id: A0A8C5XKE3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

30608:NR5A2
gene id: 30608:NR5A2
uniprot id: A0A8B7EWY5
uniprot id: A0A8B7EYV5
uniprot id: A0A8B7EYW0
uniprot id: A0A8B7EYZ0
uniprot id: A0A8C5XUH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

30608:LHFPL3
gene id: 30608:LHFPL3
uniprot id: A0A8B7F3D0
uniprot id: A0A8B7F4A7
names: Subcellular Location Annotation
messages: Membrane

30608:BLOC1S1
gene id: 30608:BLOC1S1
uniprot id: A0A8B7X7Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BLOC1S1 family.
messages: Lysosome membrane
messages: May negatively regulate aerobic respiration through mitochondrial protein lysine-acetylation. May counteract the action of the deacetylase SIRT3 by acetylating and regulating proteins of the mitochondrial respiratory chain including ATP5F1A and NDUFA9.
messages: Mitochondrion intermembrane space

30608:DCTD
gene id: 30608:DCTD
uniprot id: A0A8B7WKR9
uniprot id: A0A8C5XM02
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

30608:CLIP1
gene id: 30608:CLIP1
uniprot id: A0A8B7HJU2
uniprot id: A0A8B7HJU7
uniprot id: A0A8B7HJU9
uniprot id: A0A8B7HJV1
uniprot id: A0A8B7HJV3
uniprot id: A0A8B7HJV4
uniprot id: A0A8B7HJV7
uniprot id: A0A8B7HJV8
uniprot id: A0A8B7HJW0
uniprot id: A0A8B7HJW2
uniprot id: A0A8B7HKZ6
uniprot id: A0A8B7HL03
uniprot id: A0A8B7HL13
uniprot id: A0A8B7HMD8
uniprot id: A0A8B7HME3
uniprot id: A0A8C5W033
names: Subcellular Location Annotation
messages: cytoskeleton

30608:LOC105885139
gene id: 30608:LOC105885139
uniprot id: A0A8B7I3D9
names: Subcellular Location Annotation
messages: Membrane

30608:LEPR
gene id: 30608:LEPR
uniprot id: A0A8B7GIA8
uniprot id: A0A8B7GJB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

30608:TJP3
gene id: 30608:TJP3
uniprot id: A0A8B7GQH3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

30608:RPS24
gene id: 30608:RPS24
uniprot id: A0A8B7G6I8
uniprot id: A0A8B7G6P4
uniprot id: A0A8B7G789
uniprot id: A0A8B7G7P2
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.
messages: Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.

30608:SLC25A11
gene id: 30608:SLC25A11
uniprot id: A0A8B7WMF9
uniprot id: A0A8C5Y096
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:TUBB4B
gene id: 30608:TUBB4B
uniprot id: A0A8B7HRV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

30608:CES5A
gene id: 30608:CES5A
uniprot id: A0A8B7FQX9
uniprot id: A0A8B7FQY3
uniprot id: A0A8B7FR23
uniprot id: A0A8B7FRH4
uniprot id: A0A8B7WSY2
uniprot id: A0A8B7WSY4
uniprot id: A0A8B7WT88
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

30608:RPS6KA5
gene id: 30608:RPS6KA5
uniprot id: A0A8B7H0B6
uniprot id: A0A8B7H246
uniprot id: A0A8B7X107
uniprot id: A0A8B7X1K5
uniprot id: A0A8B7X1L0
uniprot id: A0A8B7X280
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

30608:C12H5orf30
gene id: 30608:C12H5orf30
uniprot id: A0A8B7GYH0
uniprot id: A0A8B7XD35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UNC119-binding protein family.
messages: Cytoplasm
messages: cilium

30608:LOC105868198
gene id: 30608:LOC105868198
uniprot id: A0A8B7FXP8
uniprot id: A0A8B7FXR5
uniprot id: A0A8B7FXW7
uniprot id: A0A8B7FYP9
uniprot id: A0A8B7FYU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm
messages: nucleoplasm

30608:CTNNA3
gene id: 30608:CTNNA3
uniprot id: A0A8B7G777
uniprot id: A0A8B7G7D1
uniprot id: A0A8B7G7W6
uniprot id: A0A8B7G8B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: cytoskeleton

30608:FAM162A
gene id: 30608:FAM162A
uniprot id: A0A8C5YFT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

30608:PRUNE2
gene id: 30608:PRUNE2
uniprot id: A0A8B7G012
uniprot id: A0A8B7G025
uniprot id: A0A8B7G029
uniprot id: A0A8B7G037
uniprot id: A0A8B7G043
uniprot id: A0A8B7G045
uniprot id: A0A8B7G053
uniprot id: A0A8B7G0Z0
uniprot id: A0A8B7G0Z7
uniprot id: A0A8B7G103
uniprot id: A0A8B7G1C8
uniprot id: A0A8B7G1D6
uniprot id: A0A8B7G1E2
uniprot id: A0A8C5Y6P0
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

30608:LOC105862792
gene id: 30608:LOC105862792
uniprot id: A0A8B7F9Q6
names: Similarity
messages: Belongs to the MIF family.

30608:LOC105858671
gene id: 30608:LOC105858671
uniprot id: A0A8B7EQU1
names: Similarity
messages: Belongs to the histone H2B family.

30608:GTF2IRD1
gene id: 30608:GTF2IRD1
uniprot id: A0A8B7WPH6
names: Subcellular Location Annotation
messages: Nucleus

30608:MANF
gene id: 30608:MANF
uniprot id: A0A8B7WKS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

30608:PATJ
gene id: 30608:PATJ
uniprot id: A0A8B7GI43
names: Subcellular Location Annotation
messages: tight junction

30608:KIF25
gene id: 30608:KIF25
uniprot id: A0A8B7X606
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:SOSTDC1
gene id: 30608:SOSTDC1
uniprot id: A0A8B7HHV4
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:DR1
gene id: 30608:DR1
uniprot id: A0A8B7I693
names: Similarity
messages: Belongs to the NC2 beta/DR1 family.

30608:RFX1
gene id: 30608:RFX1
uniprot id: A0A8B7I4P0
uniprot id: A0A8B7I4P6
uniprot id: A0A8C5UYY3
names: Subcellular Location Annotation
messages: Nucleus

30608:XKR7
gene id: 30608:XKR7
uniprot id: A0A8C5YDI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

30608:MRPL2
gene id: 30608:MRPL2
uniprot id: A0A8C5XGP1
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

30608:SDR42E2
gene id: 30608:SDR42E2
uniprot id: A0A8B7I428
uniprot id: A0A8B7I429
uniprot id: A0A8B7I645
names: Similarity
messages: Belongs to the 3-beta-HSD family.

30608:CD38
gene id: 30608:CD38
uniprot id: A0A8B7EHC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADP-ribosyl cyclase family.
messages: Membrane

30608:MAP2K3
gene id: 30608:MAP2K3
uniprot id: A0A8C5VIY8
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:ACSL5
gene id: 30608:ACSL5
uniprot id: A0A8B7GUG6
uniprot id: A0A8B7GUH7
uniprot id: A0A8B7GUJ0
uniprot id: A0A8B7GUJ1
uniprot id: A0A8B7GUN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion outer membrane

30608:SNTG2
gene id: 30608:SNTG2
uniprot id: A0A8B7G9F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

30608:GADD45G
gene id: 30608:GADD45G
uniprot id: A0A8B7GZT3
names: Similarity
messages: Belongs to the GADD45 family.

30608:DNAJB12
gene id: 30608:DNAJB12
uniprot id: A0A8B7G6S1
uniprot id: A0A8B7G7G5
names: Subcellular Location Annotation
messages: Membrane

30608:SLC35D2
gene id: 30608:SLC35D2
uniprot id: A0A8B7HX05
uniprot id: A0A8B7HX25
uniprot id: A0A8C5ULY8
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105861321
gene id: 30608:LOC105861321
uniprot id: A0A8B7F3V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ZNF592
gene id: 30608:ZNF592
uniprot id: A0A8B7G8N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: May be involved in transcriptional regulation.
messages: Nucleus

30608:DICER1
gene id: 30608:DICER1
uniprot id: A0A8B7FPV1
uniprot id: A0A8B7FQ57
names: Function
names: Similarity
messages: Belongs to the helicase family. Dicer subfamily.
messages: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes.

30608:CSNK1G1
gene id: 30608:CSNK1G1
uniprot id: A0A8B7FX73
uniprot id: A0A8B7FX76
uniprot id: A0A8B7FX78
uniprot id: A0A8B7FX81
uniprot id: A0A8B7FXD3
uniprot id: A0A8B7FXD8
uniprot id: A0A8B7FY65
uniprot id: A0A8B7FY96
uniprot id: A0A8B7FY99
uniprot id: A0A8B7X1N1
uniprot id: A0A8C5VWD0
uniprot id: A0A8C5VYB6
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

30608:TMTC4
gene id: 30608:TMTC4
uniprot id: A0A8B7FGB7
uniprot id: A0A8B7FGD4
uniprot id: A0A8B7FGF0
uniprot id: A0A8B7FHJ6
uniprot id: A0A8C5XQY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

30608:LOC109730023
gene id: 30608:LOC109730023
uniprot id: A0A8B7WWX2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

30608:CORO1A
gene id: 30608:CORO1A
uniprot id: A0A8B7GB33
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat coronin family.
messages: Binds actin.
messages: Membrane
messages: cell cortex
messages: cytoskeleton
messages: phagosome membrane

30608:FGF20
gene id: 30608:FGF20
uniprot id: A0A8B7HTR1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

30608:PLA2G4A
gene id: 30608:PLA2G4A
uniprot id: A0A8C5V493
names: Domain
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.

30608:LOC105870030
gene id: 30608:LOC105870030
uniprot id: A0A8B7WYD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MMP14
gene id: 30608:MMP14
uniprot id: A0A8B7FI28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Cytoplasm
messages: Melanosome

30608:ATP6AP2
gene id: 30608:ATP6AP2
uniprot id: A0A8B7HIU6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

30608:PPARD
gene id: 30608:PPARD
uniprot id: A0A8B7F3Y7
uniprot id: A0A8B7F480
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

30608:STAM2
gene id: 30608:STAM2
uniprot id: A0A8B7XAG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

30608:UNC13A
gene id: 30608:UNC13A
uniprot id: A0A8B7WX42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-13 family.
messages: Cytoplasm
messages: Membrane

30608:FOXM1
gene id: 30608:FOXM1
uniprot id: A0A8B7X6D9
names: Subcellular Location Annotation
messages: Nucleus

30608:GPR35
gene id: 30608:GPR35
uniprot id: A0A8B7FQL3
uniprot id: A0A8B7FQY2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:DNAH3
gene id: 30608:DNAH3
uniprot id: A0A8B7I470
names: Similarity
messages: Belongs to the dynein heavy chain family.

30608:LOC105867374
gene id: 30608:LOC105867374
uniprot id: A0A8B7FV70
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:PRKAR2A
gene id: 30608:PRKAR2A
uniprot id: A0A8B7GTP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

30608:BCO1
gene id: 30608:BCO1
uniprot id: A0A8B7F2B2
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

30608:MSX1
gene id: 30608:MSX1
uniprot id: A0A8B7EKP0
names: Subcellular Location Annotation
messages: Nucleus

30608:VWDE
gene id: 30608:VWDE
uniprot id: A0A8B7FUQ5
uniprot id: A0A8B7XC92
uniprot id: A0A8B7XDB5
uniprot id: A0A8B7XDZ2
uniprot id: A0A8B7XEH8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:POP5
gene id: 30608:POP5
uniprot id: A0A8C5UUH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

30608:FAM124A
gene id: 30608:FAM124A
uniprot id: A0A8B7XDR0
uniprot id: A0A8B7XDR2
uniprot id: A0A8B7XDR4
uniprot id: A0A8B7XF36
uniprot id: A0A8B7XG21
names: Similarity
messages: Belongs to the FAM124 family.

30608:TCP11
gene id: 30608:TCP11
uniprot id: A0A8B7F2S8
uniprot id: A0A8C5VM98
names: Similarity
messages: Belongs to the TCP11 family.

30608:DDIT4L
gene id: 30608:DDIT4L
uniprot id: A0A8B7EH15
uniprot id: A0A8B7EHG4
uniprot id: A0A8B7EJG7
names: Similarity
messages: Belongs to the DDIT4 family.

30608:CNN2
gene id: 30608:CNN2
uniprot id: A0A8B7F089
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

30608:OSBPL7
gene id: 30608:OSBPL7
uniprot id: A0A8B7GFC2
uniprot id: A0A8B7GFD1
uniprot id: A0A8B7GG54
names: Similarity
messages: Belongs to the OSBP family.

30608:SCN8A
gene id: 30608:SCN8A
uniprot id: A0A8B7G782
uniprot id: A0A8B7G7B8
uniprot id: A0A8B7G7D6
uniprot id: A0A8B7G7F5
uniprot id: A0A8B7G7V3
uniprot id: A0A8B7G7Y6
uniprot id: A0A8C5VLA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

30608:LOC105879216
gene id: 30608:LOC105879216
uniprot id: A0A8B7HCY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NEMP1
gene id: 30608:NEMP1
uniprot id: A0A8B7H7H0
uniprot id: A0A8B7H7H7
uniprot id: A0A8C5XPT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

30608:FAM57A
gene id: 30608:FAM57A
uniprot id: A0A8C5XD33
names: Subcellular Location Annotation
messages: Membrane

30608:LARS2
gene id: 30608:LARS2
uniprot id: A0A8B7GRP1
uniprot id: A0A8B7WSH7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

30608:TPH2
gene id: 30608:TPH2
uniprot id: A0A8B7EI41
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

30608:KIF13A
gene id: 30608:KIF13A
uniprot id: A0A8B7WKC3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:LOC105857783
gene id: 30608:LOC105857783
uniprot id: A0A8B7ELZ5
names: Subcellular Location Annotation
messages: Nucleus

30608:HNRNPA1
gene id: 30608:HNRNPA1
uniprot id: A0A8C5VMJ5
uniprot id: A0A8C5VMJ7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:SNRPA1
gene id: 30608:SNRPA1
uniprot id: A0A8B7GBT5
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

30608:MST1R
gene id: 30608:MST1R
uniprot id: A0A8B7GTR1
uniprot id: A0A8B7GTW7
uniprot id: A0A8C5VPQ8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:GUCY1A3
gene id: 30608:GUCY1A3
uniprot id: A0A8C5V3N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

30608:NPY2R
gene id: 30608:NPY2R
uniprot id: A0A8B7HMZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CSTF2
gene id: 30608:CSTF2
uniprot id: A0A8B7GIY2
uniprot id: A0A8B7GIY3
uniprot id: A0A8B7GJA9
uniprot id: A0A8B7WZ32
uniprot id: A0A8B7WZI5
uniprot id: A0A8B7X0B1
names: Subcellular Location Annotation
messages: Nucleus

30608:RWDD3
gene id: 30608:RWDD3
uniprot id: A0A8B7I888
uniprot id: A0A8C5XYC4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:MAPK10
gene id: 30608:MAPK10
uniprot id: A0A8B7GSQ0
uniprot id: A0A8B7GSZ1
uniprot id: A0A8B7GUG4
uniprot id: A0A8B7WXP2
uniprot id: A0A8B7WXP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

30608:IFNB1
gene id: 30608:IFNB1
uniprot id: A0A8B7GQG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

30608:CLDN16
gene id: 30608:CLDN16
uniprot id: A0A8B7X5C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

30608:CAPN5
gene id: 30608:CAPN5
uniprot id: A0A8B7F0P0
names: Similarity
messages: Belongs to the peptidase C2 family.

30608:NACC1
gene id: 30608:NACC1
uniprot id: A0A8B7I522
names: Subcellular Location Annotation
messages: Nucleus

30608:GIMAP6
gene id: 30608:GIMAP6
uniprot id: A0A8B7HU49
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

30608:GRP
gene id: 30608:GRP
uniprot id: A0A8B7EZJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Induces an itch response through activation of receptors present on mast cells, triggering mast cell degranulation.
messages: Secreted
messages: neuron projection
messages: secretory vesicle lumen

30608:LOC105860518
gene id: 30608:LOC105860518
uniprot id: A0A8B7EZ96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

30608:SLC26A6
gene id: 30608:SLC26A6
uniprot id: A0A8B7GTE9
uniprot id: A0A8B7GTN0
uniprot id: A0A8B7GV70
uniprot id: A0A8B7GV75
uniprot id: A0A8B7WKX8
uniprot id: A0A8B7WLN6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:SPCS2
gene id: 30608:SPCS2
uniprot id: A0A8C5XQJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:PNMA2
gene id: 30608:PNMA2
uniprot id: A0A8B7H3G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNMA family.
messages: nucleolus

30608:SPTLC2
gene id: 30608:SPTLC2
uniprot id: A0A8B7ETN3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

30608:TNFSF10
gene id: 30608:TNFSF10
uniprot id: A0A8B7EBZ8
uniprot id: A0A8B7ECK3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tumor necrosis factor family.
messages: Homotrimer.
messages: Membrane
messages: Secreted

30608:SUPT3H
gene id: 30608:SUPT3H
uniprot id: A0A8B7EUA5
uniprot id: A0A8B7EUA7
uniprot id: A0A8B7EUB1
uniprot id: A0A8B7EW99
uniprot id: A0A8C5UZG7
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105863998
gene id: 30608:LOC105863998
uniprot id: A0A8B7FGH1
names: Similarity
names: Subunit
messages: Belongs to the GST superfamily. Mu family.
messages: Homodimer.

30608:ARL14
gene id: 30608:ARL14
uniprot id: A0A8C6ELJ3
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

30608:PPP3CA
gene id: 30608:PPP3CA
uniprot id: A0A8B7WXH2
uniprot id: A0A8B7WXW7
uniprot id: A0A8B7WYB2
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

30608:DMTN
gene id: 30608:DMTN
uniprot id: A0A8B7EJI4
uniprot id: A0A8B7EJI7
uniprot id: A0A8B7ELJ0
uniprot id: A0A8B7ELJ4
names: Subcellular Location Annotation
messages: Cytoplasm

30608:UBA6
gene id: 30608:UBA6
uniprot id: A0A8B7WWQ0
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

30608:EXOC6B
gene id: 30608:EXOC6B
uniprot id: A0A8B7FBI9
uniprot id: A0A8B7FBN0
uniprot id: A0A8C5V1Z6
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

30608:ANO6
gene id: 30608:ANO6
uniprot id: A0A8B7F7L5
uniprot id: A0A8B7F7S6
uniprot id: A0A8B7F824
uniprot id: A0A8B7F871
uniprot id: A0A8B7F880
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:PEX13
gene id: 30608:PEX13
uniprot id: A0A8B7GCG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

30608:FGF14
gene id: 30608:FGF14
uniprot id: A0A8B7XEP7
uniprot id: A0A8C5UY92
uniprot id: A0A8C5VT53
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

30608:DSCC1
gene id: 30608:DSCC1
uniprot id: A0A8B7FKX6
names: Similarity
messages: Belongs to the DCC1 family.

30608:ITGA5
gene id: 30608:ITGA5
uniprot id: A0A8B7GCL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

30608:YWHAE
gene id: 30608:YWHAE
uniprot id: A0A8B7EPS4
uniprot id: A0A8C5VLS4
names: Similarity
messages: Belongs to the 14-3-3 family.

30608:COG1
gene id: 30608:COG1
uniprot id: A0A8B7FRH5
names: Similarity
messages: Belongs to the COG1 family.

30608:ZFPL1
gene id: 30608:ZFPL1
uniprot id: A0A8C5UQ34
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZFPL1 family.
messages: Interacts with GOLGA2/GM130.
messages: Membrane
messages: Required for cis-Golgi integrity and efficient ER to Golgi transport.
messages: The B box-type and RING-type zinc fingers although degenerate play a central role in function of the protein.
messages: cis-Golgi network membrane

30608:METTL3
gene id: 30608:METTL3
uniprot id: A0A8B7FJ98
names: Similarity
messages: Belongs to the MT-A70-like family.

30608:USO1
gene id: 30608:USO1
uniprot id: A0A8C5YBU3
uniprot id: A0A8C6EI98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VDP/USO1/EDE1 family.
messages: Membrane

30608:LOC105871038
gene id: 30608:LOC105871038
uniprot id: A0A8B7GB82
uniprot id: A0A8B7GBP0
uniprot id: A0A8C5W1T3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Inflammasome

30608:FAM163A
gene id: 30608:FAM163A
uniprot id: A0A8B7GWU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

30608:SNX11
gene id: 30608:SNX11
uniprot id: A0A8B7GFY2
uniprot id: A0A8C5VXT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

30608:RPL31
gene id: 30608:RPL31
uniprot id: A0A8B7EM37
uniprot id: A0A8C5XES3
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

30608:LOC105874717
gene id: 30608:LOC105874717
uniprot id: A0A8B7GU84
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

30608:FOS
gene id: 30608:FOS
uniprot id: A0A8C5VW39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Fos subfamily.
messages: cytosol

30608:STAT2
gene id: 30608:STAT2
uniprot id: A0A8B7FL32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

30608:PHACTR1
gene id: 30608:PHACTR1
uniprot id: A0A8B7FK22
uniprot id: A0A8B7FK70
uniprot id: A0A8B7FLC7
uniprot id: A0A8C5UJJ1
uniprot id: A0A8C5V893
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Nucleus
messages: Synapse

30608:RNF10
gene id: 30608:RNF10
uniprot id: A0A8B7FSF9
uniprot id: A0A8C5VD13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF10 family.
messages: Cytoplasm

30608:SFXN3
gene id: 30608:SFXN3
uniprot id: A0A8B7GNK5
uniprot id: A0A8B7GNS6
uniprot id: A0A8B7GPL9
uniprot id: A0A8C5XXS0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

30608:WRN
gene id: 30608:WRN
uniprot id: A0A8B7WTE8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

30608:NETO1
gene id: 30608:NETO1
uniprot id: A0A8B7HHG8
uniprot id: A0A8C5UVG6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:MS4A13
gene id: 30608:MS4A13
uniprot id: A0A8B7FTJ7
names: Similarity
messages: Belongs to the MS4A family.

30608:SLC12A4
gene id: 30608:SLC12A4
uniprot id: A0A8B7ES00
uniprot id: A0A8B7ES04
uniprot id: A0A8B7ES05
uniprot id: A0A8B7ES06
uniprot id: A0A8B7ETS0
uniprot id: A0A8B7EU22
uniprot id: A0A8C5XGA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

30608:LOC109729267
gene id: 30608:LOC109729267
uniprot id: A0A8B7WKT4
names: Similarity
messages: Belongs to the histone H2B family.

30608:LOC105862648
gene id: 30608:LOC105862648
uniprot id: A0A8B7F963
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:RPL35
gene id: 30608:RPL35
uniprot id: A0A8B7GV98
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

30608:SNX3
gene id: 30608:SNX3
uniprot id: A0A8B7FJ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome
messages: Endosome
messages: phagosome

30608:GTF2F1
gene id: 30608:GTF2F1
uniprot id: A0A8B7G5F5
uniprot id: A0A8B7G604
uniprot id: A0A8B7WVM3
uniprot id: A0A8B7WVN1
uniprot id: A0A8C5UT97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

30608:CDC42BPB
gene id: 30608:CDC42BPB
uniprot id: A0A8B7F1T2
uniprot id: A0A8B7F1T4
uniprot id: A0A8B7F1T6
uniprot id: A0A8B7F3S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: Cytoplasm
messages: lamellipodium

30608:TNFSF11
gene id: 30608:TNFSF11
uniprot id: A0A8B7G2Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

30608:MGAT4D
gene id: 30608:MGAT4D
uniprot id: A0A8C5Y4I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 54 family.
messages: Golgi apparatus membrane

30608:CLDN18
gene id: 30608:CLDN18
uniprot id: A0A8C5YGU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

30608:LAMP5
gene id: 30608:LAMP5
uniprot id: A0A8C5UWI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lysosome membrane

30608:PPIC
gene id: 30608:PPIC
uniprot id: A0A8B7I2G0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

30608:PCNX2
gene id: 30608:PCNX2
uniprot id: A0A8B7EGM3
uniprot id: A0A8B7EGM6
uniprot id: A0A8B7EH25
uniprot id: A0A8B7EHJ1
uniprot id: A0A8B7EJ34
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:CCDC39
gene id: 30608:CCDC39
uniprot id: A0A8B7EE27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC39 family.
messages: cilium axoneme

30608:UNC119B
gene id: 30608:UNC119B
uniprot id: A0A8C5W4K4
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

30608:ENSA
gene id: 30608:ENSA
uniprot id: A0A8B7GJ93
uniprot id: A0A8B7GJ96
uniprot id: A0A8B7GJL4
uniprot id: A0A8C5XNB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

30608:GABRQ
gene id: 30608:GABRQ
uniprot id: A0A8C5Y603
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:MRPL22
gene id: 30608:MRPL22
uniprot id: A0A8B7FPW8
uniprot id: A0A8B7FQ30
uniprot id: A0A8B7FQF1
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

30608:LOC105885136
gene id: 30608:LOC105885136
uniprot id: A0A8B7I6F5
uniprot id: A0A8B7WNW3
names: Similarity
messages: Belongs to the NDK family.

30608:LOC105861987
gene id: 30608:LOC105861987
uniprot id: A0A8B7F6G9
uniprot id: A0A8B7F6H2
uniprot id: A0A8B7F6J4
uniprot id: A0A8B7F6L7
uniprot id: A0A8B7F6M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

30608:PDE6D
gene id: 30608:PDE6D
uniprot id: A0A8B7EC81
uniprot id: A0A8C5VSU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PDE6D/unc-119 family.
messages: Cytoplasmic vesicle membrane
messages: Interacts with the prenylated catalytic subunits of PDE6, an oligomer composed of two catalytic chains and two inhibitory chains; has no effect on enzyme activity but promotes the release of the prenylated enzyme from cell membrane.
messages: Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.
messages: cilium basal body
messages: cytosol

30608:PIK3R1
gene id: 30608:PIK3R1
uniprot id: A0A8B7HL39
uniprot id: A0A8B7HL43
uniprot id: A0A8B7HMC6
uniprot id: A0A8C5UP55
uniprot id: A0A8C5XXK2
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

30608:LOC105883503
gene id: 30608:LOC105883503
uniprot id: A0A8B7HVH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:C19H5orf24
gene id: 30608:C19H5orf24
uniprot id: A0A8B7G5X9
uniprot id: A0A8B7G607
names: Similarity
messages: Belongs to the UPF0461 family.

30608:IL7
gene id: 30608:IL7
uniprot id: A0A8B7EL08
uniprot id: A0A8B7EMC4
uniprot id: A0A8C5XYI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-7/IL-9 family.
messages: Hematopoietic cytokine that plays an essential role in the development, expansion, and survival of naive and memory T-cells and B-cells thereby regulating the number of mature lymphocytes and maintaining lymphoid homeostasis.
messages: Secreted

30608:SND1
gene id: 30608:SND1
uniprot id: A0A8B7I1Q7
uniprot id: A0A8C5UKL8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs.

30608:SKA3
gene id: 30608:SKA3
uniprot id: A0A8C5W8B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA3 family.
messages: kinetochore
messages: spindle

30608:GCHFR
gene id: 30608:GCHFR
uniprot id: A0A8B7GGJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GFRP family.
messages: Membrane
messages: Nucleus membrane
messages: cytosol

30608:PSPC1
gene id: 30608:PSPC1
uniprot id: A0A8B7HBB9
uniprot id: A0A8C5VQK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PSPC family.
messages: Cytoplasm
messages: Nucleus matrix
messages: Nucleus speckle
messages: nucleolus

30608:MED1
gene id: 30608:MED1
uniprot id: A0A8B7GF77
uniprot id: A0A8B7GG00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

30608:RAP2C
gene id: 30608:RAP2C
uniprot id: A0A8C5VUI9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

30608:RPL18
gene id: 30608:RPL18
uniprot id: A0A8B7WUM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL18 family.
messages: Rough endoplasmic reticulum

30608:LOC105864060
gene id: 30608:LOC105864060
uniprot id: A0A8B7FFN4
names: Similarity
messages: Belongs to the peptidase A1 family.

30608:CRB1
gene id: 30608:CRB1
uniprot id: A0A8C5ULB5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:EDC3
gene id: 30608:EDC3
uniprot id: A0A8C5Y8K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

30608:IER2
gene id: 30608:IER2
uniprot id: A0A8B7I841
names: Similarity
messages: Belongs to the IER family.

30608:MAP2K6
gene id: 30608:MAP2K6
uniprot id: A0A8B7F579
uniprot id: A0A8C5VT34
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:LOC105863137
gene id: 30608:LOC105863137
uniprot id: A0A8B7FB69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MRPS27
gene id: 30608:MRPS27
uniprot id: A0A8B7HM73
names: Subcellular Location Annotation
messages: Mitochondrion

30608:LOC105885928
gene id: 30608:LOC105885928
uniprot id: A0A8B7WUW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Membrane

30608:LCORL
gene id: 30608:LCORL
uniprot id: A0A8B7EFE5
uniprot id: A0A8B7EH80
names: Subcellular Location Annotation
messages: Nucleus

30608:NTRK3
gene id: 30608:NTRK3
uniprot id: A0A8C5UPZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

30608:STXBP5
gene id: 30608:STXBP5
uniprot id: A0A8B7FGY7
uniprot id: A0A8B7FI05
uniprot id: A0A8C5VFW7
uniprot id: A0A8C5VYH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

30608:MYBL1
gene id: 30608:MYBL1
uniprot id: A0A8B7EZI5
uniprot id: A0A8C5VUG1
names: Subcellular Location Annotation
messages: Nucleus

30608:CLUL1
gene id: 30608:CLUL1
uniprot id: A0A8B7F1J0
uniprot id: A0A8B7F1J2
uniprot id: A0A8B7WR60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Secreted

30608:KCNS2
gene id: 30608:KCNS2
uniprot id: A0A8B7G5E6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:LIG1
gene id: 30608:LIG1
uniprot id: A0A8B7G330
uniprot id: A0A8C6EK52
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

30608:PTK7
gene id: 30608:PTK7
uniprot id: A0A8C5XIE7
names: Subcellular Location Annotation
messages: Membrane

30608:MEF2C
gene id: 30608:MEF2C
uniprot id: A0A8B7HI13
uniprot id: A0A8B7HKM7
uniprot id: A0A8B7XD73
uniprot id: A0A8B7XEG5
uniprot id: A0A8B7XEX3
uniprot id: A0A8B7XFG1
uniprot id: A0A8C5XPH6
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105881982
gene id: 30608:LOC105881982
uniprot id: A0A8B7HNZ6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

30608:LOC105883373
gene id: 30608:LOC105883373
uniprot id: A0A8B7HUY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NADK
gene id: 30608:NADK
uniprot id: A0A8B7H656
uniprot id: A0A8C5V4Z8
names: Similarity
messages: Belongs to the NAD kinase family.

30608:MRPL28
gene id: 30608:MRPL28
uniprot id: A0A8B7EGA3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

30608:DOCK5
gene id: 30608:DOCK5
uniprot id: A0A8B7HM47
names: Similarity
messages: Belongs to the DOCK family.

30608:LOC105856979
gene id: 30608:LOC105856979
uniprot id: A0A8B7X9J9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

30608:LOC105864541
gene id: 30608:LOC105864541
uniprot id: A0A8B7FHG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NOL11
gene id: 30608:NOL11
uniprot id: A0A8B7WME6
uniprot id: A0A8B7WNG7
names: Subcellular Location Annotation
messages: nucleolus

30608:EIF4A1
gene id: 30608:EIF4A1
uniprot id: A0A8C5V549
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.

30608:LOC105858287
gene id: 30608:LOC105858287
uniprot id: A0A8B7ERC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

30608:NOV
gene id: 30608:NOV
uniprot id: A0A8B7FKT2
uniprot id: A0A8B7FM37
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:WASHC5
gene id: 30608:WASHC5
uniprot id: A0A8B7HUL0
names: Similarity
messages: Belongs to the strumpellin family.

30608:UGGT1
gene id: 30608:UGGT1
uniprot id: A0A8B7FBB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

30608:EEF2K
gene id: 30608:EEF2K
uniprot id: A0A8C5V537
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. Alpha-type protein kinase family.
messages: Monomer or homodimer.
messages: Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent.

30608:SGO1
gene id: 30608:SGO1
uniprot id: A0A8B7HNN0
uniprot id: A0A8B7HPP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

30608:NDUFB3
gene id: 30608:NDUFB3
uniprot id: A0A8C5Y647
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

30608:LOC105855016
gene id: 30608:LOC105855016
uniprot id: A0A8C5XVW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Lysosome membrane

30608:NANOS2
gene id: 30608:NANOS2
uniprot id: A0A8B7G4G0
names: Similarity
messages: Belongs to the nanos family.

30608:LOC105869212
gene id: 30608:LOC105869212
uniprot id: A0A8B7X6H2
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

30608:ITGA11
gene id: 30608:ITGA11
uniprot id: A0A8B7X1R8
uniprot id: A0A8B7X1S2
uniprot id: A0A8B7X1T3
uniprot id: A0A8B7X2B7
uniprot id: A0A8B7X309
uniprot id: A0A8B7X3I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

30608:ARPC1B
gene id: 30608:ARPC1B
uniprot id: A0A8B7FYA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: Nucleus
messages: cytoskeleton

30608:ANKRD34B
gene id: 30608:ANKRD34B
uniprot id: A0A8B7GHG4
names: Similarity
messages: Belongs to the ANKRD34 family.

30608:TMEM97
gene id: 30608:TMEM97
uniprot id: A0A8B7EMP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMEM97/sigma-2 receptor family.
messages: Endoplasmic reticulum membrane
messages: Interacts with NPC1.
messages: Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

30608:CACNA1H
gene id: 30608:CACNA1H
uniprot id: A0A8B7EUI5
uniprot id: A0A8B7WNX5
uniprot id: A0A8B7WNY6
uniprot id: A0A8B7WQ79
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105876740
gene id: 30608:LOC105876740
uniprot id: A0A8B7WRS4
names: Similarity
messages: Belongs to the serpin family.

30608:PPP1R12C
gene id: 30608:PPP1R12C
uniprot id: A0A8B7H3X1
uniprot id: A0A8B7H413
uniprot id: A0A8B7H652
uniprot id: A0A8B7WV01
uniprot id: A0A8B7WWM0
names: Subcellular Location Annotation
names: Subunit
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.
messages: stress fiber

30608:PITPNM1
gene id: 30608:PITPNM1
uniprot id: A0A8B7FV08
uniprot id: A0A8B7FV69
uniprot id: A0A8B7FVY3
uniprot id: A0A8C5UPQ2
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

30608:PLA2G2E
gene id: 30608:PLA2G2E
uniprot id: A0A8B7I037
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

30608:LOC105877563
gene id: 30608:LOC105877563
uniprot id: A0A8B7H5K8
uniprot id: A0A8C5VJ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Mitochondrion intermembrane space

30608:LOC105859216
gene id: 30608:LOC105859216
uniprot id: A0A8B7ET14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SRPRB
gene id: 30608:SRPRB
uniprot id: A0A8C5YK50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:LOC105863112
gene id: 30608:LOC105863112
uniprot id: A0A8B7FB21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NPAS4
gene id: 30608:NPAS4
uniprot id: A0A8C5UNX7
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105870078
gene id: 30608:LOC105870078
uniprot id: A0A8B7G6J5
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

30608:SLC24A4
gene id: 30608:SLC24A4
uniprot id: A0A8B7EHF1
uniprot id: A0A8B7EHF2
uniprot id: A0A8B7EIE0
uniprot id: A0A8B7EJV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

30608:DBNL
gene id: 30608:DBNL
uniprot id: A0A8B7EPL5
uniprot id: A0A8B7ER86
uniprot id: A0A8B7ERR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABP1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Golgi apparatus membrane
messages: Perikaryon
messages: Postsynaptic density
messages: Synapse
messages: cell cortex
messages: clathrin-coated vesicle membrane
messages: cytoskeleton
messages: dendrite
messages: lamellipodium
messages: neuron projection
messages: podosome
messages: ruffle

30608:RPS15
gene id: 30608:RPS15
uniprot id: A0A8C5XN52
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

30608:ZNF503
gene id: 30608:ZNF503
uniprot id: A0A8B7FQ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

30608:BRF1
gene id: 30608:BRF1
uniprot id: A0A8B7F212
uniprot id: A0A8C5W491
names: Similarity
messages: Belongs to the TFIIB family.

30608:TNS1
gene id: 30608:TNS1
uniprot id: A0A8B7HRU8
uniprot id: A0A8B7HRV4
uniprot id: A0A8B7HRV8
uniprot id: A0A8B7HRW1
uniprot id: A0A8B7HRW3
uniprot id: A0A8B7HTU9
uniprot id: A0A8B7HU56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

30608:SFRP4
gene id: 30608:SFRP4
uniprot id: A0A8B7H8S2
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ACSM4
gene id: 30608:ACSM4
uniprot id: A0A8B7I7C8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

30608:GOT1
gene id: 30608:GOT1
uniprot id: A0A8B7GKV5
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

30608:AKAP4
gene id: 30608:AKAP4
uniprot id: A0A8B7FTD7
uniprot id: A0A8B7FTE4
names: Similarity
messages: Belongs to the AKAP110 family.

30608:LOC105858168
gene id: 30608:LOC105858168
uniprot id: A0A8B7ENW6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

30608:XKR4
gene id: 30608:XKR4
uniprot id: A0A8B7EU52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

30608:FAHD1
gene id: 30608:FAHD1
uniprot id: A0A8B7EUU9
names: Similarity
messages: Belongs to the FAH family.

30608:AIF1
gene id: 30608:AIF1
uniprot id: A0A8B7EQ32
uniprot id: A0A8C5YFC2
names: Subcellular Location Annotation
messages: ruffle membrane

30608:TRMT6
gene id: 30608:TRMT6
uniprot id: A0A8B7FPH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRM6/GCD10 family.
messages: Nucleus

30608:PDXK
gene id: 30608:PDXK
uniprot id: A0A8B7HCE6
uniprot id: A0A8C5URP3
names: Similarity
messages: Belongs to the pyridoxine kinase family.

30608:LOC105859402
gene id: 30608:LOC105859402
uniprot id: A0A8B7EVW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.
messages: centrosome

30608:IDH2
gene id: 30608:IDH2
uniprot id: A0A8B7G8M5
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

30608:GSDMD
gene id: 30608:GSDMD
uniprot id: A0A8B7FII5
uniprot id: A0A8C5XAY1
uniprot id: A0A8C5YC24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

30608:SYNE4
gene id: 30608:SYNE4
uniprot id: A0A8B7H2Q0
names: Similarity
messages: Belongs to the nesprin family.

30608:KHSRP
gene id: 30608:KHSRP
uniprot id: A0A8B7G4M1
uniprot id: A0A8B7G4P9
uniprot id: A0A8B7G5F1
uniprot id: A0A8B7G601
names: Subcellular Location Annotation
messages: Nucleus

30608:ERC2
gene id: 30608:ERC2
uniprot id: A0A8B7FIR8
uniprot id: A0A8B7FIS7
uniprot id: A0A8B7FIS8
uniprot id: A0A8B7FIT2
uniprot id: A0A8B7FIW0
uniprot id: A0A8B7FIW7
uniprot id: A0A8B7FIZ9
uniprot id: A0A8B7FJ04
uniprot id: A0A8B7FJ08
uniprot id: A0A8B7FK68
uniprot id: A0A8B7WL31
names: Subcellular Location Annotation
messages: Cytoplasm

30608:DENND5A
gene id: 30608:DENND5A
uniprot id: A0A8B7HNY0
uniprot id: A0A8C5UQY3
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:HS3ST1
gene id: 30608:HS3ST1
uniprot id: A0A8B7EFM8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:EIF5
gene id: 30608:EIF5
uniprot id: A0A8C5XGK4
names: Function
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).

30608:IFNG
gene id: 30608:IFNG
uniprot id: A0A8C5UTE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II (or gamma) interferon family.
messages: Homodimer.
messages: Secreted
messages: Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation. Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation. Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activation, nuclear translocation and transcription of IFNG-regulated genes. Many of the induced genes are transcription factors such as IRF1 that are able to further drive regulation of a next wave of transcription. Plays a role in class I antigen presentation pathway by inducing a replacement of catalytic proteasome subunits with immunoproteasome subunits. In turn, increases the quantity, quality, and repertoire of peptides for class I MHC loading. Increases the efficiency of peptide generation also by inducing the expression of activator PA28 that associates with the proteasome and alters its proteolytic cleavage preference. Up-regulates as well MHC II complexes on the cell surface by promoting expression of several key molecules such as cathepsins B/CTSB, H/CTSH, and L/CTSL. Participates in the regulation of hematopoietic stem cells during development and under homeostatic conditions by affecting their development, quiescence, and differentiation.

30608:SNRPA
gene id: 30608:SNRPA
uniprot id: A0A8B7H1H1
uniprot id: A0A8B7H1H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM U1 A/B'' family.
messages: Nucleus

30608:CDH11
gene id: 30608:CDH11
uniprot id: A0A8C5XY65
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

30608:AP1S2
gene id: 30608:AP1S2
uniprot id: A0A8B7HQS0
uniprot id: A0A8C5VIN3
uniprot id: A0A8C5VWG0
uniprot id: A0A8C5W5N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

30608:PCSK5
gene id: 30608:PCSK5
uniprot id: A0A8B7G008
uniprot id: A0A8B7G040
uniprot id: A0A8B7G0Y4
uniprot id: A0A8C5XNB2
names: Similarity
messages: Belongs to the peptidase S8 family.

30608:AP2A1
gene id: 30608:AP2A1
uniprot id: A0A8B7FMJ9
uniprot id: A0A8C5XZB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

30608:RAPSN
gene id: 30608:RAPSN
uniprot id: A0A8B7I102
names: Similarity
messages: Belongs to the RAPsyn family.

30608:LOC105855519
gene id: 30608:LOC105855519
uniprot id: A0A8B7ECC2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:ATP6V1B1
gene id: 30608:ATP6V1B1
uniprot id: A0A8B7FBR4
uniprot id: A0A8B7FBX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

30608:ABLIM3
gene id: 30608:ABLIM3
uniprot id: A0A8B7EPS0
uniprot id: A0A8B7EPS5
uniprot id: A0A8B7EPT2
uniprot id: A0A8B7EPX3
uniprot id: A0A8B7ERF9
uniprot id: A0A8B7WVN0
uniprot id: A0A8B7WX11
names: Subcellular Location Annotation
messages: Cytoplasm

30608:LOC105879706
gene id: 30608:LOC105879706
uniprot id: A0A8B7HEX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

30608:CACNG2
gene id: 30608:CACNG2
uniprot id: A0A8B7HWP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

30608:RPN2
gene id: 30608:RPN2
uniprot id: A0A8B7FNK1
uniprot id: A0A8B7FP08
uniprot id: A0A8C5W5Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

30608:GUSB
gene id: 30608:GUSB
uniprot id: A0A8B7GAI1
uniprot id: A0A8B7GAY0
uniprot id: A0A8B7GB44
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Homotetramer.
messages: Inhibited by L-aspartic acid.
messages: Lysosome
messages: Plays an important role in the degradation of dermatan and keratan sulfates.

30608:GNPDA1
gene id: 30608:GNPDA1
uniprot id: A0A8B7F9A1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

30608:HS6ST3
gene id: 30608:HS6ST3
uniprot id: A0A8B7GPU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

30608:PLAUR
gene id: 30608:PLAUR
uniprot id: A0A8B7G3K6
uniprot id: A0A8B7G3K7
uniprot id: A0A8B7G3L0
uniprot id: A0A8B7G4Z2
uniprot id: A0A8C5XYT2
names: Function
names: Subcellular Location Annotation
messages: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
messages: Cell membrane
messages: Membrane
messages: invadopodium membrane

30608:SYBU
gene id: 30608:SYBU
uniprot id: A0A8B7HUK2
uniprot id: A0A8B7HUL2
uniprot id: A0A8B7HWP6
uniprot id: A0A8B7HWS6
uniprot id: A0A8B7X9Z0
uniprot id: A0A8C5V462
names: Subcellular Location Annotation
messages: Membrane

30608:LPAR3
gene id: 30608:LPAR3
uniprot id: A0A8B7F5N0
uniprot id: A0A8C5XRH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:IQSEC2
gene id: 30608:IQSEC2
uniprot id: A0A8B7F2E4
uniprot id: A0A8B7F2E5
uniprot id: A0A8B7F2E6
uniprot id: A0A8B7F2F0
uniprot id: A0A8B7F3R4
uniprot id: A0A8B7F3R5
uniprot id: A0A8B7F3R7
uniprot id: A0A8B7F418
uniprot id: A0A8C5UUR8
uniprot id: A0A8C5XL54
names: Similarity
messages: Belongs to the BRAG family.

30608:KCNJ16
gene id: 30608:KCNJ16
uniprot id: A0A8B7F5A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

30608:ZNF277
gene id: 30608:ZNF277
uniprot id: A0A8B7EBN5
uniprot id: A0A8C5V5L1
names: Similarity
messages: Belongs to the ZNF277 family.

30608:FDXR
gene id: 30608:FDXR
uniprot id: A0A8B7HBM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion
messages: Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.

30608:SIX6
gene id: 30608:SIX6
uniprot id: A0A8B7HBX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus

30608:FAM193A
gene id: 30608:FAM193A
uniprot id: A0A8B7EED1
uniprot id: A0A8B7EEE1
uniprot id: A0A8B7EEZ4
uniprot id: A0A8B7EF25
uniprot id: A0A8B7EF31
uniprot id: A0A8B7EGY6
uniprot id: A0A8B7WQ01
names: Similarity
messages: Belongs to the FAM193 family.

30608:NANOS1
gene id: 30608:NANOS1
uniprot id: A0A8B7EIW8
names: Similarity
messages: Belongs to the nanos family.

30608:ARID1A
gene id: 30608:ARID1A
uniprot id: A0A8B7FCW1
uniprot id: A0A8B7FCX2
uniprot id: A0A8B7FD31
uniprot id: A0A8C5W015
names: Subcellular Location Annotation
messages: Nucleus

30608:KAT6B
gene id: 30608:KAT6B
uniprot id: A0A8B7G0E6
uniprot id: A0A8B7G0F2
uniprot id: A0A8B7G0H2
uniprot id: A0A8B7G0H7
uniprot id: A0A8B7G0I7
uniprot id: A0A8B7G1S1
uniprot id: A0A8B7G1S6
uniprot id: A0A8B7WM87
uniprot id: A0A8B7WNA1
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

30608:LOC105884105
gene id: 30608:LOC105884105
uniprot id: A0A8B7HYG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:KIF12
gene id: 30608:KIF12
uniprot id: A0A8B7GMU3
uniprot id: A0A8B7GN19
uniprot id: A0A8B7GNU6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:CORO6
gene id: 30608:CORO6
uniprot id: A0A8B7EMQ2
uniprot id: A0A8B7EPY2
names: Similarity
messages: Belongs to the WD repeat coronin family.

30608:GOLGA5
gene id: 30608:GOLGA5
uniprot id: A0A8B7EIF2
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.
messages: Membrane

30608:PGF
gene id: 30608:PGF
uniprot id: A0A8B7ER50
uniprot id: A0A8B7ER79
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

30608:EYA1
gene id: 30608:EYA1
uniprot id: A0A8B7GSC5
uniprot id: A0A8B7GSD0
uniprot id: A0A8B7GSD6
uniprot id: A0A8B7GSE0
uniprot id: A0A8B7GSE1
uniprot id: A0A8B7GSE6
uniprot id: A0A8B7GSF0
uniprot id: A0A8B7GSK8
uniprot id: A0A8B7GSL3
uniprot id: A0A8B7GSL8
uniprot id: A0A8B7GSM2
uniprot id: A0A8B7GSN0
uniprot id: A0A8B7GSP0
uniprot id: A0A8B7GU09
uniprot id: A0A8B7GU25
uniprot id: A0A8B7GU31
uniprot id: A0A8B7X9L3
uniprot id: A0A8B7X9L9
uniprot id: A0A8B7X9M4
uniprot id: A0A8B7X9M5
uniprot id: A0A8B7X9N0
uniprot id: A0A8B7XAB1
uniprot id: A0A8B7XAC4
uniprot id: A0A8B7XBA4
uniprot id: A0A8B7XBQ2
uniprot id: A0A8B7XBQ7
uniprot id: A0A8B7XBR6
uniprot id: A0A8C5XZT7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

30608:PSMD3
gene id: 30608:PSMD3
uniprot id: A0A8B7GFW7
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

30608:TMPRSS13
gene id: 30608:TMPRSS13
uniprot id: A0A8B7GZF0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105885424
gene id: 30608:LOC105885424
uniprot id: A0A8B7I4Q3
names: Subcellular Location Annotation
messages: Nucleus

30608:ANXA5
gene id: 30608:ANXA5
uniprot id: A0A8B7HR50
names: Domain
names: Function
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.

30608:MGAM
gene id: 30608:MGAM
uniprot id: A0A8B7GLQ8
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:GPX5
gene id: 30608:GPX5
uniprot id: A0A8B7ESK3
uniprot id: A0A8B7WKS4
uniprot id: A0A8C5V1Q5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

30608:CHUK
gene id: 30608:CHUK
uniprot id: A0A8B7WLQ8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:TDRD7
gene id: 30608:TDRD7
uniprot id: A0A8B7GN35
uniprot id: A0A8B7GNE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TDRD7 family.
messages: Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis.
messages: Cytoplasm
messages: Found in a mRNP complex, at least composed of TDRD1, TDRD6, TDRD7 and DDX4. Found in a complex containing CABLES1, CDK16 and CDK17. Interacts with CABLES1, CDK17 and PIWIL1.

30608:MTCH1
gene id: 30608:MTCH1
uniprot id: A0A8B7F308
uniprot id: A0A8B7F311
uniprot id: A0A8B7F314
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:ITGB3BP
gene id: 30608:ITGB3BP
uniprot id: A0A8B7GI78
uniprot id: A0A8B7GI85
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription coregulator that can have both coactivator and corepressor functions.
messages: centromere
messages: kinetochore

30608:LOC105879404
gene id: 30608:LOC105879404
uniprot id: A0A8B7HDS0
uniprot id: A0A8C5XLP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

30608:MURC
gene id: 30608:MURC
uniprot id: A0A8B7GNF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola
messages: sarcomere

30608:FADS2
gene id: 30608:FADS2
uniprot id: A0A8B7HAH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Endoplasmic reticulum membrane

30608:SEC23A
gene id: 30608:SEC23A
uniprot id: A0A8B7GIR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

30608:LOC105873718
gene id: 30608:LOC105873718
uniprot id: A0A8B7XB68
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

30608:LOC105855832
gene id: 30608:LOC105855832
uniprot id: A0A8B7EDL1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:WNT8B
gene id: 30608:WNT8B
uniprot id: A0A8B7GMU1
uniprot id: A0A8B7WLS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

30608:USP33
gene id: 30608:USP33
uniprot id: A0A8B7HXV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: centrosome
messages: perinuclear region

30608:EFS
gene id: 30608:EFS
uniprot id: A0A8B7FHV1
names: Similarity
messages: Belongs to the CAS family.

30608:VMA21
gene id: 30608:VMA21
uniprot id: A0A8B7EBE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the V0 complex of the vacuolar ATPase (V-ATPase).
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

30608:LOC105883501
gene id: 30608:LOC105883501
uniprot id: A0A8B7HXP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:WNT2
gene id: 30608:WNT2
uniprot id: A0A8B7G368
uniprot id: Q2QL85
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity).
messages: Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
messages: Secreted
messages: extracellular matrix

30608:LOC105869622
gene id: 30608:LOC105869622
uniprot id: A0A8B7G4H0
names: Similarity
messages: Belongs to the PRAME family.

30608:SLC35F4
gene id: 30608:SLC35F4
uniprot id: A0A8B7HSU3
uniprot id: A0A8C5XSY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

30608:FGD6
gene id: 30608:FGD6
uniprot id: A0A8B7X6B0
names: Subcellular Location Annotation
messages: cytoskeleton

30608:GLP1R
gene id: 30608:GLP1R
uniprot id: A0A8B7F3A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

30608:HOXA10
gene id: 30608:HOXA10
uniprot id: A0A8C5VPH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

30608:HOXA5
gene id: 30608:HOXA5
uniprot id: A0A8B7H0N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

30608:ADGRB3
gene id: 30608:ADGRB3
uniprot id: A0A8B7FHP5
uniprot id: A0A8B7FJ09
names: Subcellular Location Annotation
messages: Membrane

30608:TTYH1
gene id: 30608:TTYH1
uniprot id: A0A8B7H3U9
uniprot id: A0A8B7H3Y9
uniprot id: A0A8B7H625
uniprot id: A0A8C5VH59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable chloride channel.

30608:LOC105882445
gene id: 30608:LOC105882445
uniprot id: A0A8C5VE73
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

30608:CPT1C
gene id: 30608:CPT1C
uniprot id: A0A8B7FMF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

30608:LUC7L
gene id: 30608:LUC7L
uniprot id: A0A8B7EFE8
uniprot id: A0A8B7EFX2
uniprot id: A0A8B7EG70
uniprot id: A0A8B7WNY3
names: Similarity
messages: Belongs to the Luc7 family.

30608:PSPN
gene id: 30608:PSPN
uniprot id: A0A8C5VUB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

30608:SLC25A29
gene id: 30608:SLC25A29
uniprot id: A0A8B7F4H7
uniprot id: A0A8B7F4I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:INTS14
gene id: 30608:INTS14
uniprot id: A0A8B7FXM0
uniprot id: A0A8C5XMV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INTS14 family.
messages: Nucleus
messages: Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.

30608:BMPR2
gene id: 30608:BMPR2
uniprot id: A0A8B7EJH1
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

30608:IER5L
gene id: 30608:IER5L
uniprot id: A0A8C5VR57
names: Similarity
messages: Belongs to the IER family.

30608:UNCX
gene id: 30608:UNCX
uniprot id: A0A8C6EIS5
names: Subcellular Location Annotation
messages: Nucleus

30608:FAM122A
gene id: 30608:FAM122A
uniprot id: A0A8B7EDG2
names: Similarity
messages: Belongs to the FAM122 family.

30608:LOC105875649
gene id: 30608:LOC105875649
uniprot id: A0A8B7GXD2
uniprot id: A0A8B7GXJ3
names: Similarity
messages: Belongs to the mTERF family.

30608:USP13
gene id: 30608:USP13
uniprot id: A0A8C5YFZ3
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

30608:AU129 gp08
gene id: 30608:AU129_gp08
uniprot id: A0A0U2RWF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

30608:BAK1
gene id: 30608:BAK1
uniprot id: A0A8B7X619
uniprot id: A0A8C5VG46
names: Similarity
messages: Belongs to the Bcl-2 family.

30608:RAB3B
gene id: 30608:RAB3B
uniprot id: A0A8B7H5I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

30608:THBS3
gene id: 30608:THBS3
uniprot id: A0A8C5VRR2
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ZNRF3
gene id: 30608:ZNRF3
uniprot id: A0A8B7WTM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZNRF3 family.
messages: Cell membrane
messages: Membrane

30608:RIPPLY3
gene id: 30608:RIPPLY3
uniprot id: A0A8B7HMM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

30608:FGGY
gene id: 30608:FGGY
uniprot id: A0A8B7HRQ7
uniprot id: A0A8B7HRR2
uniprot id: A0A8B7HRS1
uniprot id: A0A8B7HU20
uniprot id: A0A8B7XAX3
names: Similarity
messages: Belongs to the FGGY kinase family.

30608:CASC1
gene id: 30608:CASC1
uniprot id: A0A8B7EJZ3
uniprot id: A0A8B7EKB0
uniprot id: A0A8B7EMC3
uniprot id: A0A8C5VH77
uniprot id: A0A8C5YHW8
names: Similarity
messages: Belongs to the DNAI7 family.

30608:HSPB3
gene id: 30608:HSPB3
uniprot id: A0A8B7FSY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Nucleus

30608:LOC105883382
gene id: 30608:LOC105883382
uniprot id: A0A8B7HUZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105884156
gene id: 30608:LOC105884156
uniprot id: A0A8B7HYL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CFLAR
gene id: 30608:CFLAR
uniprot id: A0A8B7EIL5
uniprot id: A0A8B7EIL7
uniprot id: A0A8B7EIZ3
names: Similarity
messages: Belongs to the peptidase C14A family.

30608:FAM135B
gene id: 30608:FAM135B
uniprot id: A0A8B7EB53
uniprot id: A0A8B7EBG6
uniprot id: A0A8B7EBH1
uniprot id: A0A8B7EDI8
uniprot id: A0A8C5YAP6
names: Similarity
messages: Belongs to the FAM135 family.

30608:SCNN1G
gene id: 30608:SCNN1G
uniprot id: A0A8B7HF30
uniprot id: A0A8B7HF52
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105883506
gene id: 30608:LOC105883506
uniprot id: A0A8C5XS27
names: Similarity
messages: Belongs to the globin family.

30608:ASPHD2
gene id: 30608:ASPHD2
uniprot id: A0A8B7FSQ8
uniprot id: A0A8B7FSU2
uniprot id: A0A8C5XE44
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

30608:CDCA7L
gene id: 30608:CDCA7L
uniprot id: A0A8B7GYK1
uniprot id: A0A8B7GYK2
uniprot id: A0A8B7GYM3
uniprot id: A0A8B7H0H2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:HLX
gene id: 30608:HLX
uniprot id: A0A8B7EA22
names: Subcellular Location Annotation
messages: Nucleus

30608:INSL5
gene id: 30608:INSL5
uniprot id: A0A8C6EHY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

30608:ADRA2C
gene id: 30608:ADRA2C
uniprot id: A0A8B7EXX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105867199
gene id: 30608:LOC105867199
uniprot id: A0A8B7FTI0
names: Function
names: Similarity
messages: Belongs to the MS4A family.
messages: May be involved in signal transduction as a component of a multimeric receptor complex.

30608:USP49
gene id: 30608:USP49
uniprot id: A0A8B7X4F1
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

30608:LOC105860824
gene id: 30608:LOC105860824
uniprot id: A0A8B7F2V9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:GAB1
gene id: 30608:GAB1
uniprot id: A0A8B7HNG0
uniprot id: A0A8B7HNG1
uniprot id: A0A8B7HQ31
uniprot id: A0A8B7HQX6
names: Similarity
messages: Belongs to the GAB family.

30608:PRIMPOL
gene id: 30608:PRIMPOL
uniprot id: A0A8B7HR96
uniprot id: A0A8B7HRA1
uniprot id: A0A8B7HRA2
uniprot id: A0A8B7HRB0
uniprot id: A0A8B7HT79
uniprot id: A0A8B7HTL7
uniprot id: A0A8B7WKN0
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

30608:ADCY1
gene id: 30608:ADCY1
uniprot id: A0A8B7G8W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

30608:HYAL2
gene id: 30608:HYAL2
uniprot id: A0A8C5XET6
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

30608:GIPC1
gene id: 30608:GIPC1
uniprot id: A0A8B7FWL4
uniprot id: A0A8B7FWS6
names: Similarity
messages: Belongs to the GIPC family.

30608:ATP5S
gene id: 30608:ATP5S
uniprot id: A0A8B7FWK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP synthase subunit s family.
messages: Homotetramer. Associates with ATP synthase.
messages: Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway.
messages: Membrane
messages: Mitochondrion inner membrane

30608:TMEM150A
gene id: 30608:TMEM150A
uniprot id: A0A8B7H0X6
uniprot id: A0A8B7H0Y4
uniprot id: A0A8B7H2Y5
uniprot id: A0A8C5VAS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRAM/TMEM150 family.
messages: Cell membrane
messages: Membrane

30608:TEKT3
gene id: 30608:TEKT3
uniprot id: A0A8B7F6L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

30608:ASB17
gene id: 30608:ASB17
uniprot id: A0A8B7HYR6
names: Function
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.
messages: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

30608:CNOT6
gene id: 30608:CNOT6
uniprot id: A0A8B7WQU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

30608:CAMK2N1
gene id: 30608:CAMK2N1
uniprot id: A0A8B7I0Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAMK2N family.
messages: Synapse

30608:CYLD
gene id: 30608:CYLD
uniprot id: A0A8B7GBU8
uniprot id: A0A8B7GBV3
uniprot id: A0A8B7GCD5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: centrosome
messages: cilium basal body
messages: perinuclear region
messages: spindle

30608:LOC105872033
gene id: 30608:LOC105872033
uniprot id: A0A8B7GEU4
uniprot id: A0A8B7GFA7
names: Similarity
messages: Belongs to the intermediate filament family.

30608:ADPRM
gene id: 30608:ADPRM
uniprot id: A0A8B7H8W1
uniprot id: A0A8B7H8X0
names: Similarity
names: Subunit
messages: Belongs to the ADPRibase-Mn family.
messages: Monomer.

30608:COL4A3BP
gene id: 30608:COL4A3BP
uniprot id: A0A8B7HNJ6
uniprot id: A0A8B7HNK5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

30608:THOC7
gene id: 30608:THOC7
uniprot id: A0A8B7GRU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

30608:LOC105859817
gene id: 30608:LOC105859817
uniprot id: A0A8B7EXW9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

30608:ATP2C1
gene id: 30608:ATP2C1
uniprot id: A0A8B7GHQ1
uniprot id: A0A8B7GHQ4
uniprot id: A0A8B7GHQ6
uniprot id: A0A8B7GI32
uniprot id: A0A8C5YJ60
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Golgi stack membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer. Homodimer.
messages: trans-Golgi network membrane

30608:MBOAT7
gene id: 30608:MBOAT7
uniprot id: A0A8B7GSH4
uniprot id: A0A8B7GSR3
names: Subcellular Location Annotation
messages: Membrane

30608:WISP3
gene id: 30608:WISP3
uniprot id: A0A8B7FJ28
uniprot id: A0A8B7FJ65
uniprot id: A0A8B7FJB0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:NDUFB10
gene id: 30608:NDUFB10
uniprot id: A0A8B7EUV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
messages: Belongs to the complex I NDUFB10 subunit family.
messages: Mitochondrion inner membrane

30608:MARCO
gene id: 30608:MARCO
uniprot id: A0A8B7GEW1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:POLA2
gene id: 30608:POLA2
uniprot id: A0A8B7H9Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

30608:SEMA4F
gene id: 30608:SEMA4F
uniprot id: A0A8B7I0F4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ADAM33
gene id: 30608:ADAM33
uniprot id: A0A8B7FQM6
uniprot id: A0A8B7WQE4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:THBD
gene id: 30608:THBD
uniprot id: A0A8B7EJ21
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with ITGAL, ITGAM and ITGB2.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

30608:AFF4
gene id: 30608:AFF4
uniprot id: A0A8B7G6J3
uniprot id: A0A8B7G723
names: Similarity
messages: Belongs to the AF4 family.

30608:SUZ12
gene id: 30608:SUZ12
uniprot id: A0A8B7EIB2
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

30608:ARPC2
gene id: 30608:ARPC2
uniprot id: A0A8C5VH46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Cell projection
messages: Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Interacts with SHANK3; the interaction probably mediates the association of SHANK3 with the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton
messages: synaptosome

30608:RIN2
gene id: 30608:RIN2
uniprot id: A0A8B7FUD6
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

30608:LOC105868755
gene id: 30608:LOC105868755
uniprot id: A0A8B7G174
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CA9
gene id: 30608:CA9
uniprot id: A0A8B7GS41
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

30608:LOC105855581
gene id: 30608:LOC105855581
uniprot id: A0A8B7EF91
names: Similarity
messages: Belongs to the FAM47 family.

30608:ATP4B
gene id: 30608:ATP4B
uniprot id: A0A8C6EH33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

30608:SFR1
gene id: 30608:SFR1
uniprot id: A0A8B7GS52
uniprot id: A0A8B7GSD1
uniprot id: A0A8B7GSF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

30608:CER1
gene id: 30608:CER1
uniprot id: A0A8B7GPT5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:IL1RAP
gene id: 30608:IL1RAP
uniprot id: A0A8B7X3M1
uniprot id: A0A8B7X3P3
uniprot id: A0A8B7X477
uniprot id: A0A8B7X5D7
uniprot id: A0A8C6ELR4
uniprot id: A0A8C6EM13
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

30608:WNT2B
gene id: 30608:WNT2B
uniprot id: A0A8B7HB20
uniprot id: A0A8B7HB25
uniprot id: A0A8C5USB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

30608:LOC105883666
gene id: 30608:LOC105883666
uniprot id: A0A8B7HYR4
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

30608:ANAPC13
gene id: 30608:ANAPC13
uniprot id: A0A8B7HYD7
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

30608:CDIPT
gene id: 30608:CDIPT
uniprot id: A0A8C5VKY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

30608:DHX9
gene id: 30608:DHX9
uniprot id: A0A8C5UUP8
uniprot id: A0A8C6EI32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Nucleus

30608:TM2D1
gene id: 30608:TM2D1
uniprot id: A0A8C6EK72
names: Subcellular Location Annotation
messages: Membrane

30608:KALRN
gene id: 30608:KALRN
uniprot id: A0A8B7HFN7
uniprot id: A0A8B7HFN8
uniprot id: A0A8B7HFP5
uniprot id: A0A8B7HFP6
uniprot id: A0A8B7HFR2
uniprot id: A0A8B7HFS0
uniprot id: A0A8B7HGA2
uniprot id: A0A8B7HIC3
uniprot id: A0A8B7X4D9
uniprot id: A0A8B7X4E5
uniprot id: A0A8B7X4F5
uniprot id: A0A8B7X4F7
uniprot id: A0A8B7X4G0
uniprot id: A0A8B7X4G7
uniprot id: A0A8B7X4H2
uniprot id: A0A8B7X4J3
uniprot id: A0A8B7X500
uniprot id: A0A8B7X507
uniprot id: A0A8B7X648
uniprot id: A0A8B7X653
uniprot id: A0A8B7X657
uniprot id: A0A8B7X662
uniprot id: A0A8B7X682
uniprot id: A0A8B7X685
uniprot id: A0A8B7X690
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm

30608:NEDD8
gene id: 30608:NEDD8
uniprot id: A0A8C5W0Z9
names: Similarity
messages: Belongs to the ubiquitin family.

30608:SLC44A5
gene id: 30608:SLC44A5
uniprot id: A0A8B7HY90
uniprot id: A0A8B7HY91
uniprot id: A0A8B7HYA0
uniprot id: A0A8B7HYA5
uniprot id: A0A8B7I0V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

30608:HOOK2
gene id: 30608:HOOK2
uniprot id: A0A8B7I4R7
uniprot id: A0A8B7I4U6
uniprot id: A0A8B7I6R9
uniprot id: A0A8B7I7V8
uniprot id: A0A8B7I7W4
uniprot id: A0A8C5V6E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

30608:LGI2
gene id: 30608:LGI2
uniprot id: A0A8B7EFA8
uniprot id: A0A8B7EH52
names: Subcellular Location Annotation
messages: Secreted

30608:RABGGTB
gene id: 30608:RABGGTB
uniprot id: A0A8B7HYP5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

30608:MED24
gene id: 30608:MED24
uniprot id: A0A8B7GF38
uniprot id: A0A8B7GFJ8
uniprot id: A0A8B7GFV6
uniprot id: A0A8B7GFW1
uniprot id: A0A8B7GFW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 24 family.
messages: Nucleus

30608:HLF
gene id: 30608:HLF
uniprot id: A0A8B7HC44
uniprot id: A0A8B7HGG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

30608:ZRANB2
gene id: 30608:ZRANB2
uniprot id: A0A8B7I0U5
uniprot id: A0A8B7I1G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZRANB2 family.
messages: Nucleus
messages: Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.

30608:ZC3H12A
gene id: 30608:ZC3H12A
uniprot id: A0A8B7HEH0
names: Similarity
messages: Belongs to the ZC3H12 family.

30608:IP6K3
gene id: 30608:IP6K3
uniprot id: A0A8B7F304
uniprot id: A0A8B7F3Z5
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

30608:ADAM19
gene id: 30608:ADAM19
uniprot id: A0A8B7HI92
uniprot id: A0A8B7HI94
uniprot id: A0A8B7HJ79
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:NELFE
gene id: 30608:NELFE
uniprot id: A0A8B7ENR8
uniprot id: A0A8C5W6J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NELF-E family.
messages: Chromosome
messages: Nucleus

30608:AFAP1L1
gene id: 30608:AFAP1L1
uniprot id: A0A8B7WVC2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in podosome and invadosome formation.
messages: invadopodium
messages: podosome

30608:ATP6V0A2
gene id: 30608:ATP6V0A2
uniprot id: A0A8C5URU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

30608:LOC105858044
gene id: 30608:LOC105858044
uniprot id: A0A8B7EN61
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

30608:DPF1
gene id: 30608:DPF1
uniprot id: A0A8B7H212
uniprot id: A0A8B7H213
uniprot id: A0A8B7H214
uniprot id: A0A8B7H217
uniprot id: A0A8B7H218
uniprot id: A0A8B7H269
uniprot id: A0A8B7H452
names: Similarity
messages: Belongs to the requiem/DPF family.

30608:SHANK1
gene id: 30608:SHANK1
uniprot id: A0A8B7FLI6
uniprot id: A0A8C5VIS3
uniprot id: A0A8C5W1H0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Postsynaptic density

30608:CRISP3
gene id: 30608:CRISP3
uniprot id: A0A8B7G2Q5
uniprot id: A0A8B7G2Q7
uniprot id: A0A8B7G3J9
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SNRPD3
gene id: 30608:SNRPD3
uniprot id: A0A8C5VRU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as core component of spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.
messages: cytosol

30608:KATNAL2
gene id: 30608:KATNAL2
uniprot id: A0A8B7F134
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily.
messages: Cytoplasm
messages: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
messages: cytoskeleton
messages: spindle
messages: spindle pole

30608:LOC105875478
gene id: 30608:LOC105875478
uniprot id: A0A8B7GWT0
names: Subcellular Location Annotation
messages: Nucleus

30608:PDE8A
gene id: 30608:PDE8A
uniprot id: A0A8B7G8N3
uniprot id: A0A8B7G949
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.

30608:TSPAN17
gene id: 30608:TSPAN17
uniprot id: A0A8B7HI47
uniprot id: A0A8B7HI74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

30608:LOC105860279
gene id: 30608:LOC105860279
uniprot id: A0A8B7F047
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:BPNT1
gene id: 30608:BPNT1
uniprot id: A0A8B7I7H6
uniprot id: A0A8B7I7I3
uniprot id: A0A8B7I7K3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

30608:LOC105877355
gene id: 30608:LOC105877355
uniprot id: A0A8B7H4H9
uniprot id: A0A8C5VM02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

30608:ASPHD1
gene id: 30608:ASPHD1
uniprot id: A0A8B7GAY1
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

30608:SYN2
gene id: 30608:SYN2
uniprot id: A0A8B7HU18
names: Similarity
messages: Belongs to the synapsin family.

30608:WFIKKN2
gene id: 30608:WFIKKN2
uniprot id: A0A8B7I3B0
uniprot id: A0A8C5V818
names: Similarity
messages: Belongs to the WFIKKN family.

30608:HGFAC
gene id: 30608:HGFAC
uniprot id: A0A8B7EF00
uniprot id: A0A8B7EGW3
uniprot id: A0A8C5XCN7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LTB
gene id: 30608:LTB
uniprot id: A0A8C5VSF7
names: Similarity
messages: Belongs to the tumor necrosis factor family.

30608:POLR3GL
gene id: 30608:POLR3GL
uniprot id: A0A8B7G5B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

30608:RHO
gene id: 30608:RHO
uniprot id: A0A8B7HU52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

30608:LOC105869687
gene id: 30608:LOC105869687
uniprot id: A0A8B7WW67
uniprot id: A0A8B7WW70
uniprot id: A0A8B7WWH4
uniprot id: A0A8B7WXW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

30608:LOC105878655
gene id: 30608:LOC105878655
uniprot id: A0A8B7HAR0
names: Subcellular Location Annotation
messages: Secreted

30608:CELSR1
gene id: 30608:CELSR1
uniprot id: A0A8B7FTI4
uniprot id: A0A8B7FTI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

30608:DHODH
gene id: 30608:DHODH
uniprot id: A0A8B7WRY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway.
messages: Mitochondrion inner membrane

30608:LOC105863157
gene id: 30608:LOC105863157
uniprot id: A0A8B7FBW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:F8
gene id: 30608:F8
uniprot id: A0A8B7X0H7
names: Similarity
messages: Belongs to the multicopper oxidase family.

30608:NT5DC1
gene id: 30608:NT5DC1
uniprot id: A0A8B7FJ50
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

30608:LOC105865799
gene id: 30608:LOC105865799
uniprot id: A0A8B7FP28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105872193
gene id: 30608:LOC105872193
uniprot id: A0A8B7GFI6
names: Similarity
messages: Belongs to the intermediate filament family.

30608:GJD4
gene id: 30608:GJD4
uniprot id: A0A8B7GFG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

30608:KCNJ11
gene id: 30608:KCNJ11
uniprot id: A0A8B7HGY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ11 subfamily.
messages: Membrane

30608:VEGFC
gene id: 30608:VEGFC
uniprot id: A0A8B7GSA4
uniprot id: A0A8B7GSJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

30608:PLIN2
gene id: 30608:PLIN2
uniprot id: A0A8B7XCL3
names: Similarity
messages: Belongs to the perilipin family.

30608:SLC16A10
gene id: 30608:SLC16A10
uniprot id: A0A8B7FIX1
uniprot id: A0A8B7FJ51
names: Subcellular Location Annotation
messages: Membrane

30608:GPR180
gene id: 30608:GPR180
uniprot id: A0A8B7XF49
uniprot id: A0A8C5UUG2
names: Subcellular Location Annotation
messages: Membrane

30608:LANCL3
gene id: 30608:LANCL3
uniprot id: A0A8B7ECM9
names: Similarity
messages: Belongs to the LanC-like protein family.

30608:TOMM5
gene id: 30608:TOMM5
uniprot id: A0A8B7GN82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

30608:LOC105872179
gene id: 30608:LOC105872179
uniprot id: A0A8C5V147
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:LOC105861277
gene id: 30608:LOC105861277
uniprot id: A0A8B7F3T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PTCH1
gene id: 30608:PTCH1
uniprot id: A0A8C5XJR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

30608:ATXN3
gene id: 30608:ATXN3
uniprot id: A0A8B7H016
uniprot id: A0A8B7H020
uniprot id: A0A8B7H021
uniprot id: A0A8B7H024
uniprot id: A0A8B7H085
uniprot id: A0A8B7H216
uniprot id: A0A8C5W7T1
names: Subcellular Location Annotation
messages: Nucleus

30608:SERPINF2
gene id: 30608:SERPINF2
uniprot id: A0A8B7EPF7
uniprot id: A0A8B7EQ63
names: Similarity
messages: Belongs to the serpin family.

30608:PPP1R3B
gene id: 30608:PPP1R3B
uniprot id: A0A8B7ELW1
names: Subunit
messages: Interacts with glycogen, PPP1CC catalytic subunit of PP1 and PYGL. Associates with glycogen particles. Forms complexes with debranching enzyme, glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.

30608:THEMIS
gene id: 30608:THEMIS
uniprot id: A0A8C5WAX5
names: Similarity
messages: Belongs to the themis family.

30608:SLC39A5
gene id: 30608:SLC39A5
uniprot id: A0A8B7FJZ2
uniprot id: A0A8B7FLF9
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105869684
gene id: 30608:LOC105869684
uniprot id: A0A8B7WVZ5
uniprot id: A0A8B7WWN3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:ST6GALNAC6
gene id: 30608:ST6GALNAC6
uniprot id: A0A8B7GVM3
uniprot id: A0A8B7GX95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

30608:CTSE
gene id: 30608:CTSE
uniprot id: A0A8C5WAX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A1 family.
messages: Endosome
messages: Homodimer; disulfide-linked.
messages: May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.

30608:VANGL1
gene id: 30608:VANGL1
uniprot id: A0A8B7G693
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

30608:LOC105882193
gene id: 30608:LOC105882193
uniprot id: A0A8B7HPT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:EGFLAM
gene id: 30608:EGFLAM
uniprot id: A0A8B7EC57
uniprot id: A0A8B7XCW4
uniprot id: A0A8C5VVK9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:CNPY2
gene id: 30608:CNPY2
uniprot id: A0A8C5XPI7
names: Similarity
messages: Belongs to the canopy family.

30608:MTX1
gene id: 30608:MTX1
uniprot id: A0A8B7GKE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

30608:LOC105872749
gene id: 30608:LOC105872749
uniprot id: A0A8B7GHZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105870479
gene id: 30608:LOC105870479
uniprot id: A0A8B7G8C8
names: Similarity
messages: Belongs to the PRAME family.

30608:SLC25A21
gene id: 30608:SLC25A21
uniprot id: A0A8B7GI11
uniprot id: A0A8B7GIE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:RNASE12
gene id: 30608:RNASE12
uniprot id: A0A8B7FIF2
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

30608:TAP1
gene id: 30608:TAP1
uniprot id: A0A8B7IAI6
names: Similarity
messages: Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.

30608:CHGA
gene id: 30608:CHGA
uniprot id: A0A8B7EHG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

30608:GTPBP1
gene id: 30608:GTPBP1
uniprot id: A0A8B7EQ58
uniprot id: A0A8B7ESA6
uniprot id: A0A8B7X760
names: Function
messages: Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity.

30608:STXBP1
gene id: 30608:STXBP1
uniprot id: A0A8B7GVD7
uniprot id: A0A8C5XQD2
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

30608:PIAS3
gene id: 30608:PIAS3
uniprot id: A0A8B7G585
uniprot id: A0A8B7G591
uniprot id: A0A8B7G610
uniprot id: A0A8C5W4Z8
uniprot id: A0A8C5W7A0
names: Similarity
messages: Belongs to the PIAS family.

30608:HSD3B7
gene id: 30608:HSD3B7
uniprot id: A0A8C5WAN3
names: Similarity
messages: Belongs to the 3-beta-HSD family.

30608:KCNJ6
gene id: 30608:KCNJ6
uniprot id: A0A8B7HLB6
uniprot id: A0A8B7WY59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ6 subfamily.
messages: Membrane

30608:LOC105858107
gene id: 30608:LOC105858107
uniprot id: A0A8B7X5A0
names: Similarity
messages: Belongs to the MHC class I family.

30608:TLX2
gene id: 30608:TLX2
uniprot id: A0A8B7I0F5
names: Subcellular Location Annotation
messages: Nucleus

30608:CDC37L1
gene id: 30608:CDC37L1
uniprot id: A0A8B7EFC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

30608:HEBP1
gene id: 30608:HEBP1
uniprot id: A0A8B7H188
names: Similarity
messages: Belongs to the HEBP family.

30608:ATXN2L
gene id: 30608:ATXN2L
uniprot id: A0A8B7FXX8
uniprot id: A0A8B7FXY6
uniprot id: A0A8B7FY09
uniprot id: A0A8B7FY39
uniprot id: A0A8B7FY43
uniprot id: A0A8B7FY48
uniprot id: A0A8B7FY53
uniprot id: A0A8B7FYX3
uniprot id: A0A8B7FYX7
uniprot id: A0A8B7FYY2
uniprot id: A0A8B7FZ30
uniprot id: A0A8B7FZ36
uniprot id: A0A8C5VWW7
names: Similarity
messages: Belongs to the ataxin-2 family.

30608:LIMS1
gene id: 30608:LIMS1
uniprot id: A0A8B7EEZ9
uniprot id: A0A8B7EFJ7
uniprot id: A0A8B7EFK2
uniprot id: A0A8B7EFQ9
uniprot id: A0A8B7EHJ3
uniprot id: A0A8C5Y8Q0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.
messages: Cell membrane
messages: Part of the heterotrimeric IPP complex composed of integrin-linked kinase (ILK), LIMS1 or LIMS2, and PARVA.
messages: focal adhesion

30608:B3GNT8
gene id: 30608:B3GNT8
uniprot id: A0A8B7G361
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:PTER
gene id: 30608:PTER
uniprot id: A0A8B7FKQ7
uniprot id: A0A8B7FKV8
uniprot id: A0A8C5VFM5
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105870764
gene id: 30608:LOC105870764
uniprot id: A0A8B7WSM5
uniprot id: A0A8B7WU24
names: Similarity
messages: Belongs to the MHC class I family.

30608:NIT2
gene id: 30608:NIT2
uniprot id: A0A8B7ETP3
uniprot id: A0A8B7EVL2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

30608:NUP155
gene id: 30608:NUP155
uniprot id: A0A8B7EC31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.
messages: nuclear pore complex

30608:SLC27A5
gene id: 30608:SLC27A5
uniprot id: A0A8B7FHC6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

30608:TSPAN14
gene id: 30608:TSPAN14
uniprot id: A0A8B7GCM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

30608:LOC105862126
gene id: 30608:LOC105862126
uniprot id: A0A8B7F711
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105866499
gene id: 30608:LOC105866499
uniprot id: A0A8B7FQT8
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

30608:LOC105859916
gene id: 30608:LOC105859916
uniprot id: A0A8B7EYC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PLCB3
gene id: 30608:PLCB3
uniprot id: A0A8B7HCC4
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

30608:LOC105860161
gene id: 30608:LOC105860161
uniprot id: A0A8B7EXN0
uniprot id: A0A8B7EXN1
uniprot id: A0A8B7EXN4
uniprot id: A0A8B7EXN5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

30608:STK4
gene id: 30608:STK4
uniprot id: A0A8B7HFV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

30608:LOC109730176
gene id: 30608:LOC109730176
uniprot id: A0A8B7WYV1
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

30608:LOC105862321
gene id: 30608:LOC105862321
uniprot id: A0A8B7WXJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

30608:TBX10
gene id: 30608:TBX10
uniprot id: A0A8B7FUF6
uniprot id: A0A8B7FUF9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

30608:ADCYAP1
gene id: 30608:ADCYAP1
uniprot id: A0A8B7F1N0
uniprot id: A0A8B7F3Q4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucagon family.
messages: Interacts with ADCYAP1R1 (via N-terminal extracellular domain).
messages: Secreted

30608:PTP4A3
gene id: 30608:PTP4A3
uniprot id: A0A8B7FFT2
uniprot id: A0A8B7FG07
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

30608:TM4SF1
gene id: 30608:TM4SF1
uniprot id: A0A8B7HL69
uniprot id: A0A8B7HNN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

30608:CDH1
gene id: 30608:CDH1
uniprot id: A0A8B7ERW7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
messages: Membrane
messages: trans-Golgi network

30608:LOC105869496
gene id: 30608:LOC105869496
uniprot id: A0A8C5VGT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

30608:TM7SF2
gene id: 30608:TM7SF2
uniprot id: A0A8B7H9W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

30608:LOC105883461
gene id: 30608:LOC105883461
uniprot id: A0A8B7HVB8
uniprot id: A0A8B7HXG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:HEXA
gene id: 30608:HEXA
uniprot id: A0A8B7GLM4
uniprot id: A0A8B7GM89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

30608:MFSD5
gene id: 30608:MFSD5
uniprot id: A0A8B7GA77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Cell membrane
messages: Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
messages: Membrane

30608:LOC105857556
gene id: 30608:LOC105857556
uniprot id: A0A8C5XZD4
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

30608:CBX5
gene id: 30608:CBX5
uniprot id: A0A8B7GBA1
uniprot id: A0A8B7GBT6
names: Subcellular Location Annotation
messages: Nucleus

30608:GSTO2
gene id: 30608:GSTO2
uniprot id: A0A8C5XTG6
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

30608:LOC105862355
gene id: 30608:LOC105862355
uniprot id: A0A8B7F7Y2
names: Subcellular Location Annotation
messages: Membrane

30608:MAP4K2
gene id: 30608:MAP4K2
uniprot id: A0A8B7H9R9
uniprot id: A0A8B7H9S7
uniprot id: A0A8B7H9T1
uniprot id: A0A8B7HCJ7
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

30608:CLCN4
gene id: 30608:CLCN4
uniprot id: A0A8B7HTD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

30608:CDT1
gene id: 30608:CDT1
uniprot id: A0A8B7WSR1
names: Similarity
messages: Belongs to the Cdt1 family.

30608:MRPS5
gene id: 30608:MRPS5
uniprot id: A0A8B7X4A5
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

30608:GALNT5
gene id: 30608:GALNT5
uniprot id: A0A8B7ESQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

30608:BAZ1B
gene id: 30608:BAZ1B
uniprot id: A0A8C5VAZ1
names: Subcellular Location Annotation
messages: Nucleus

30608:VTI1A
gene id: 30608:VTI1A
uniprot id: A0A8B7GUP9
uniprot id: A0A8B7GUS6
uniprot id: A0A8B7GUU9
uniprot id: A0A8B7GUW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

30608:HMMR
gene id: 30608:HMMR
uniprot id: A0A8B7FIY4
names: Subcellular Location Annotation
messages: spindle

30608:C17H16orf72
gene id: 30608:C17H16orf72
uniprot id: A0A8B7HRV2
uniprot id: A0A8B7HU64
names: Similarity
messages: Belongs to the TAPR1 family.

30608:ISYNA1
gene id: 30608:ISYNA1
uniprot id: A0A8C5XKW8
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

30608:SRF
gene id: 30608:SRF
uniprot id: A0A8B7H036
uniprot id: A0A8C5XLK2
names: Subcellular Location Annotation
messages: Nucleus

30608:ACTC1
gene id: 30608:ACTC1
uniprot id: A0A8B7GH11
names: Similarity
messages: Belongs to the actin family.

30608:SEMA7A
gene id: 30608:SEMA7A
uniprot id: A0A8B7F758
uniprot id: A0A8B7F790
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:NBL1
gene id: 30608:NBL1
uniprot id: A0A8C5V9W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

30608:CDCA8
gene id: 30608:CDCA8
uniprot id: A0A8C5YAI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the borealin family.
messages: centromere

30608:RBM8A
gene id: 30608:RBM8A
uniprot id: A0A8B7G5B0
uniprot id: A0A8B7G6M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBM8A family.
messages: Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
messages: Cytoplasm
messages: Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.
messages: Nucleus
messages: Nucleus speckle

30608:IL33
gene id: 30608:IL33
uniprot id: A0A8C5V2J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family. Highly divergent.
messages: Chromosome
messages: Nucleus
messages: Secreted
messages: Vesicle
messages: secretory vesicle

30608:DNAJC18
gene id: 30608:DNAJC18
uniprot id: A0A8C5XGT1
names: Subcellular Location Annotation
messages: Membrane

30608:CFB
gene id: 30608:CFB
uniprot id: A0A8B7ENP3
uniprot id: A0A8C5XGC5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:BRAF
gene id: 30608:BRAF
uniprot id: A0A8B7GKH9
uniprot id: A0A8B7GKI0
uniprot id: A0A8B7GKU6
uniprot id: A0A8B7GLP4
uniprot id: A0A8B7XCV6
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

30608:LOC105866929
gene id: 30608:LOC105866929
uniprot id: A0A8B7FTH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

30608:LOC105865497
gene id: 30608:LOC105865497
uniprot id: A0A8B7FLG3
uniprot id: A0A8B7FLM5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:FUCA2
gene id: 30608:FUCA2
uniprot id: A0A8B7GLS7
uniprot id: A0A8B7GM44
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

30608:GABARAPL2
gene id: 30608:GABARAPL2
uniprot id: A0A8B7GWV6
names: Similarity
messages: Belongs to the ATG8 family.

30608:ALB
gene id: 30608:ALB
uniprot id: A0A8B7EZV2
names: Subcellular Location Annotation
messages: Secreted

30608:DDX31
gene id: 30608:DDX31
uniprot id: A0A8B7EW93
uniprot id: A0A8C5XRG2
names: Similarity
messages: Belongs to the DEAD box helicase family.

30608:LOC105864100
gene id: 30608:LOC105864100
uniprot id: A0A8B7WV32
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:CLDN3
gene id: 30608:CLDN3
uniprot id: A0A8B7ERF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the claudin family.
messages: Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

30608:LOC105876368
gene id: 30608:LOC105876368
uniprot id: A0A8B7H0E4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:FAM168A
gene id: 30608:FAM168A
uniprot id: A0A8B7EY85
uniprot id: A0A8B7X3T8
uniprot id: A0A8C5Y5Z3
names: Similarity
messages: Belongs to the FAM168 family.

30608:DEFB124
gene id: 30608:DEFB124
uniprot id: A0A8B7WQD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

30608:LOC105856576
gene id: 30608:LOC105856576
uniprot id: A0A8B7EJJ4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

30608:CDC42
gene id: 30608:CDC42
uniprot id: A0A8B7GM58
uniprot id: A0A8B7GMQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.
messages: centrosome

30608:HDAC3
gene id: 30608:HDAC3
uniprot id: A0A8B7F9F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
messages: Nucleus

30608:LOC105864775
gene id: 30608:LOC105864775
uniprot id: A0A8B7FIP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105883399
gene id: 30608:LOC105883399
uniprot id: A0A8B7HX64
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105859372
gene id: 30608:LOC105859372
uniprot id: A0A8B7X6U5
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

30608:SETDB1
gene id: 30608:SETDB1
uniprot id: A0A8B7GJJ1
uniprot id: A0A8B7GKA5
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

30608:ARL3
gene id: 30608:ARL3
uniprot id: A0A8B7GSI4
uniprot id: A0A8C5VHY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

30608:UBE2R2
gene id: 30608:UBE2R2
uniprot id: A0A8C6EL70
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:AKT1
gene id: 30608:AKT1
uniprot id: A0A8B7F3U4
uniprot id: A0A8C5VV71
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

30608:LPIN2
gene id: 30608:LPIN2
uniprot id: A0A8B7F1A8
uniprot id: A0A8B7F1B0
uniprot id: A0A8B7F312
names: Similarity
messages: Belongs to the lipin family.

30608:LOC105864458
gene id: 30608:LOC105864458
uniprot id: A0A8C5VD65
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Secreted

30608:DKC1
gene id: 30608:DKC1
uniprot id: A0A8B7WZF4
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

30608:SOX11
gene id: 30608:SOX11
uniprot id: A0A8B7I910
names: Subcellular Location Annotation
messages: Nucleus

30608:MC2R
gene id: 30608:MC2R
uniprot id: A0A8B7F1M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MRAP; increasing ligand-sensitivity and generation of cAMP. Interacts with MRAP2; competing with MRAP for binding to MC2R and impairing the binding of corticotropin (ACTH).
messages: Membrane
messages: Receptor for corticotropin (ACTH). This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (cAMP).

30608:LOC109730286
gene id: 30608:LOC109730286
uniprot id: A0A8B7WZY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

30608:DNAH9
gene id: 30608:DNAH9
uniprot id: A0A8B7WMC6
names: Similarity
messages: Belongs to the dynein heavy chain family.

30608:CFAP45
gene id: 30608:CFAP45
uniprot id: A0A8B7F9F3
uniprot id: A0A8B7F9W0
names: Similarity
messages: Belongs to the CFAP45 family.

30608:LOC105869993
gene id: 30608:LOC105869993
uniprot id: A0A8B7G5Y8
uniprot id: A0A8B7G5Y9
uniprot id: A0A8B7G616
uniprot id: A0A8B7G780
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

30608:NPB
gene id: 30608:NPB
uniprot id: A0A8B7I4G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

30608:RGS3
gene id: 30608:RGS3
uniprot id: A0A8B7GMM1
uniprot id: A0A8B7GN42
uniprot id: A0A8B7XB76
uniprot id: A0A8C5VPQ3
uniprot id: A0A8C5XVK9
names: Subcellular Location Annotation
messages: Cytoplasm

30608:CHMP4B
gene id: 30608:CHMP4B
uniprot id: A0A8C5YAI6
names: Similarity
messages: Belongs to the SNF7 family.

30608:UTP15
gene id: 30608:UTP15
uniprot id: A0A8B7HP88
names: Subcellular Location Annotation
messages: nucleolus

30608:PEX2
gene id: 30608:PEX2
uniprot id: A0A8B7EIZ9
names: Function
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.
messages: Somewhat implicated in the biogenesis of peroxisomes.

30608:MRAP
gene id: 30608:MRAP
uniprot id: A0A8B7HGT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:PHB2
gene id: 30608:PHB2
uniprot id: A0A8C5VVY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

30608:PICALM
gene id: 30608:PICALM
uniprot id: A0A8B7EHR7
uniprot id: A0A8B7EHR9
uniprot id: A0A8B7EHS4
uniprot id: A0A8B7EHS7
uniprot id: A0A8B7EHS8
uniprot id: A0A8B7EHT1
uniprot id: A0A8B7EI59
uniprot id: A0A8B7EI64
uniprot id: A0A8B7EI68
uniprot id: A0A8B7EI73
uniprot id: A0A8B7EIS3
uniprot id: A0A8B7EIS7
uniprot id: A0A8B7EIT4
uniprot id: A0A8B7EIU0
uniprot id: A0A8B7EK66
uniprot id: A0A8B7EK71
uniprot id: A0A8B7EK76
uniprot id: A0A8B7EK79
uniprot id: A0A8B7EK84
uniprot id: A0A8B7X3E1
uniprot id: A0A8C5VKF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PICALM/SNAP91 family.
messages: Membrane

30608:SH3RF2
gene id: 30608:SH3RF2
uniprot id: A0A8C5VIL5
names: Similarity
messages: Belongs to the SH3RF family.

30608:OBSCN
gene id: 30608:OBSCN
uniprot id: A0A8B7XFV0
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

30608:MS4A18
gene id: 30608:MS4A18
uniprot id: A0A8B7X5I9
names: Similarity
messages: Belongs to the MS4A family.

30608:PPP1R7
gene id: 30608:PPP1R7
uniprot id: A0A8C5XZQ7
names: Similarity
messages: Belongs to the SDS22 family.

30608:SKOR1
gene id: 30608:SKOR1
uniprot id: A0A8B7GLP6
names: Similarity
messages: Belongs to the SKI family.

30608:SLC10A7
gene id: 30608:SLC10A7
uniprot id: A0A8B7WKG7
uniprot id: A0A8B7WKG9
uniprot id: A0A8B7WKK5
uniprot id: A0A8C5VTF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Cell membrane
messages: Does not show transport activity towards bile acids or steroid sulfates.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

30608:SCAMP5
gene id: 30608:SCAMP5
uniprot id: A0A8C5W223
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

30608:NOP58
gene id: 30608:NOP58
uniprot id: A0A8B7EIF4
uniprot id: A0A8B7EIF8
uniprot id: A0A8B7EIT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

30608:PSMA5
gene id: 30608:PSMA5
uniprot id: A0A8B7FFI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

30608:SUMO1
gene id: 30608:SUMO1
uniprot id: A0A8C5VEN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

30608:PCYOX1L
gene id: 30608:PCYOX1L
uniprot id: A0A8B7EPW0
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

30608:PPM1N
gene id: 30608:PPM1N
uniprot id: A0A8C5VIC4
names: Similarity
messages: Belongs to the PP2C family.

30608:GFOD1
gene id: 30608:GFOD1
uniprot id: A0A8C5UJQ5
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

30608:PHKG1
gene id: 30608:PHKG1
uniprot id: A0A8B7GAJ2
uniprot id: A0A8B7GAY5
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

30608:SEC22B
gene id: 30608:SEC22B
uniprot id: A0A8B7G6H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

30608:NAF1
gene id: 30608:NAF1
uniprot id: A0A8C6EDL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

30608:LOC105872656
gene id: 30608:LOC105872656
uniprot id: A0A8B7GHJ3
names: Similarity
messages: Belongs to the transferrin family.

30608:PSMA7
gene id: 30608:PSMA7
uniprot id: A0A8C5V207
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

30608:GAD1
gene id: 30608:GAD1
uniprot id: A0A8B7HJ38
uniprot id: A0A8B7HLM9
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

30608:GRIN3B
gene id: 30608:GRIN3B
uniprot id: A0A8B7F251
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

30608:GTF2H5
gene id: 30608:GTF2H5
uniprot id: A0A8B7FZN1
uniprot id: A0A8B7G0L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

30608:B3GALT1
gene id: 30608:B3GALT1
uniprot id: A0A8B7XAB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:LOC105865940
gene id: 30608:LOC105865940
uniprot id: A0A8B7FNV1
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

30608:SAP30L
gene id: 30608:SAP30L
uniprot id: A0A8B7FQ46
names: Similarity
messages: Belongs to the SAP30 family.

30608:LOC105870332
gene id: 30608:LOC105870332
uniprot id: A0A8B7WM46
names: Similarity
messages: Belongs to the KHDC1 family.

30608:SUSD1
gene id: 30608:SUSD1
uniprot id: A0A8B7GMR6
uniprot id: A0A8B7GMS1
uniprot id: A0A8B7GMS5
uniprot id: A0A8B7GMT0
uniprot id: A0A8B7GN25
uniprot id: A0A8B7GNA4
uniprot id: A0A8B7GP33
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:MPC1
gene id: 30608:MPC1
uniprot id: A0A8B7H6Y1
uniprot id: A0A8B7H6Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

30608:HMGN2
gene id: 30608:HMGN2
uniprot id: A0A8B7HM59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

30608:HSPA8
gene id: 30608:HSPA8
uniprot id: A0A8B7I6L6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

30608:BCAT1
gene id: 30608:BCAT1
uniprot id: A0A8B7EK11
uniprot id: A0A8B7EL94
uniprot id: A0A8B7EMD6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

30608:TRMT10C
gene id: 30608:TRMT10C
uniprot id: A0A8B7HGH3
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

30608:PER3
gene id: 30608:PER3
uniprot id: A0A8B7I7H0
uniprot id: A0A8B7I9I4
uniprot id: A0A8B7IAU8
uniprot id: A0A8B7WQB7
uniprot id: A0A8B7WQG1
uniprot id: A0A8B7WRU0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:AP3D1
gene id: 30608:AP3D1
uniprot id: A0A8B7F1V7
uniprot id: A0A8C5V992
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

30608:TET1
gene id: 30608:TET1
uniprot id: A0A8B7G737
uniprot id: A0A8B7G744
uniprot id: A0A8B7G791
uniprot id: A0A8B7G7S8
uniprot id: A0A8C5YG92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

30608:KPNA1
gene id: 30608:KPNA1
uniprot id: A0A8B7HFT4
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

30608:LOC105865361
gene id: 30608:LOC105865361
uniprot id: A0A8B7FKY5
uniprot id: A0A8C5XV92
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:MAST4
gene id: 30608:MAST4
uniprot id: A0A8B7HP71
uniprot id: A0A8B7HP74
uniprot id: A0A8B7HP75
uniprot id: A0A8B7HRL3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

30608:ELOVL2
gene id: 30608:ELOVL2
uniprot id: A0A8B7FKF3
uniprot id: A0A8B7FLR3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL2 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

30608:KRT9
gene id: 30608:KRT9
uniprot id: A0A8B7GET9
names: Similarity
messages: Belongs to the intermediate filament family.

30608:SCN1A
gene id: 30608:SCN1A
uniprot id: A0A8B7FTQ7
uniprot id: A0A8B7FUD2
uniprot id: A0A8B7FUM1
uniprot id: A0A8B7X8B3
uniprot id: A0A8B7XAB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

30608:SUMF1
gene id: 30608:SUMF1
uniprot id: A0A8B7G3B5
uniprot id: A0A8B7G3B6
uniprot id: A0A8B7G464
uniprot id: A0A8C5VNS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

30608:ALKBH5
gene id: 30608:ALKBH5
uniprot id: A0A8C5Y7U4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alkB family.
messages: Monomer.
messages: Nucleus speckle

30608:LOC105876420
gene id: 30608:LOC105876420
uniprot id: A0A8B7H2H4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:PPA2
gene id: 30608:PPA2
uniprot id: A0A8B7HC81
uniprot id: A0A8B7HC87
uniprot id: A0A8B7HC89
names: Similarity
messages: Belongs to the PPase family.

30608:CWF19L2
gene id: 30608:CWF19L2
uniprot id: A0A8B7X3G7
names: Similarity
messages: Belongs to the CWF19 family.

30608:LBH
gene id: 30608:LBH
uniprot id: A0A8B7HZT8
uniprot id: A0A8B7HZU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LBH family.
messages: Cytoplasm
messages: Nucleus
messages: Transcriptional activator.

30608:CORO2A
gene id: 30608:CORO2A
uniprot id: A0A8B7GN20
uniprot id: A0A8B7GNC6
uniprot id: A0A8B7GNK6
names: Similarity
messages: Belongs to the WD repeat coronin family.

30608:ITGA2B
gene id: 30608:ITGA2B
uniprot id: A0A8B7HXW5
uniprot id: A0A8B7HY21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

30608:MAN1B1
gene id: 30608:MAN1B1
uniprot id: A0A8B7XDR7
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

30608:NACC2
gene id: 30608:NACC2
uniprot id: A0A8B7HJG2
uniprot id: A0A8B7HKK4
names: Subcellular Location Annotation
messages: Nucleus

30608:GDF7
gene id: 30608:GDF7
uniprot id: A0A8B7I0V2
names: Similarity
messages: Belongs to the TGF-beta family.

30608:LOC105883499
gene id: 30608:LOC105883499
uniprot id: A0A8B7HVF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NKX1-1
gene id: 30608:NKX1-1
uniprot id: A0A8B7HNX3
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC109730635
gene id: 30608:LOC109730635
uniprot id: A0A8C5Y831
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIII family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

30608:ABL2
gene id: 30608:ABL2
uniprot id: A0A8B7GWU7
uniprot id: A0A8B7GWV2
uniprot id: A0A8B7GWW6
uniprot id: A0A8B7GWW7
uniprot id: A0A8B7GWX1
uniprot id: A0A8B7GX05
uniprot id: A0A8B7GYR3
uniprot id: A0A8C5UST8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

30608:IFI30
gene id: 30608:IFI30
uniprot id: A0A8B7WVQ5
names: Similarity
names: Subunit
messages: Belongs to the GILT family.
messages: Dimer; disulfide-linked.

30608:SOAT2
gene id: 30608:SOAT2
uniprot id: A0A8B7G8N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:CHRND
gene id: 30608:CHRND
uniprot id: A0A8B7X9G0
uniprot id: A0A8C5VYD4
uniprot id: A0A8C5YEC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:TMEM138
gene id: 30608:TMEM138
uniprot id: A0A8B7HAN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

30608:RAX
gene id: 30608:RAX
uniprot id: A0A8C5VXH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

30608:MFAP5
gene id: 30608:MFAP5
uniprot id: A0A8B7H8U2
uniprot id: A0A8B7HBG6
uniprot id: A0A8C5VC59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

30608:CAPNS1
gene id: 30608:CAPNS1
uniprot id: A0A8B7H2F9
uniprot id: A0A8B7H2G0
uniprot id: A0A8B7H2G4
uniprot id: A0A8B7H2L8
uniprot id: A0A8B7H4M0
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer or heterodimer of a large (catalytic) and a small (regulatory) subunit. In presence of calcium, the heterodimer dissociates.
messages: Membrane

30608:FOXI3
gene id: 30608:FOXI3
uniprot id: A0A8B7H136
names: Subcellular Location Annotation
messages: Nucleus

30608:TIMELESS
gene id: 30608:TIMELESS
uniprot id: A0A8B7FL44
uniprot id: A0A8B7FLA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the timeless family.
messages: Nucleus

30608:NXF3
gene id: 30608:NXF3
uniprot id: A0A8B7I0S8
uniprot id: A0A8B7WYP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm

30608:LOC105856702
gene id: 30608:LOC105856702
uniprot id: A0A8B7EJV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105872943
gene id: 30608:LOC105872943
uniprot id: A0A8B7X2X3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose.
messages: The manganese ion interacts primarily with the substrate UDP-N-acetylglucosamine.
messages: The stem domain mediates specific interaction with beta-linked N-acetylglucosamine moieties of O-glycosylated proteins. It also interacts with its product, N-acetyl-beta-D-glucosaminyl-(1->2)-O-alpha-D-mannosylprotein.

30608:LOC105867750
gene id: 30608:LOC105867750
uniprot id: A0A8B7FW99
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:C6H6orf120
gene id: 30608:C6H6orf120
uniprot id: A0A8B7HKG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0669 family.
messages: May be involved in induction of apoptosis in CD4(+) T-cells, but not CD8(+) T-cells or hepatocytes.
messages: Secreted

30608:TNFRSF11B
gene id: 30608:TNFRSF11B
uniprot id: A0A8C5V3I3
names: Caution
names: Function
names: Subunit
messages: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ADAMTS1
gene id: 30608:ADAMTS1
uniprot id: A0A8B7GBF6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:SPOCK2
gene id: 30608:SPOCK2
uniprot id: A0A8B7G6S9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:DHPS
gene id: 30608:DHPS
uniprot id: A0A8C5XN46
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

30608:MASP1
gene id: 30608:MASP1
uniprot id: A0A8B7I2W8
uniprot id: A0A8B7I2X8
uniprot id: A0A8B7I4Y5
uniprot id: A0A8B7I5W4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:PROK1
gene id: 30608:PROK1
uniprot id: A0A8C5URN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

30608:ALAS2
gene id: 30608:ALAS2
uniprot id: A0A8B7F7M4
uniprot id: A0A8C5W5M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

30608:SMO
gene id: 30608:SMO
uniprot id: A0A8B7I1W1
uniprot id: A0A8B7I1W9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:CRCP
gene id: 30608:CRCP
uniprot id: A0A8C5VH45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

30608:SFRP5
gene id: 30608:SFRP5
uniprot id: A0A8B7GKT8
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ODF1
gene id: 30608:ODF1
uniprot id: A0A8C5URI5
names: Function
messages: Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.

30608:RNPC3
gene id: 30608:RNPC3
uniprot id: A0A8C5XSA6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Found in a complex with m(7)G-capped U12 snRNA. Interacts with PDCD7.
messages: Nucleus
messages: Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA.

30608:SSBP2
gene id: 30608:SSBP2
uniprot id: A0A8B7HPT1
uniprot id: A0A8B7HPT3
uniprot id: A0A8B7HPT5
uniprot id: A0A8B7HRJ0
names: Subcellular Location Annotation
messages: Nucleus

30608:CSN3
gene id: 30608:CSN3
uniprot id: A0A8B7WX04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kappa-casein family.
messages: Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
messages: Secreted

30608:LTBR
gene id: 30608:LTBR
uniprot id: A0A8B7G221
uniprot id: A0A8B7G2X4
uniprot id: A0A8B7G3G5
uniprot id: A0A8B7X688
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:MAML3
gene id: 30608:MAML3
uniprot id: A0A8B7GG47
uniprot id: A0A8B7GGK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

30608:OLFM2
gene id: 30608:OLFM2
uniprot id: A0A8B7I5G7
uniprot id: A0A8C5VF05
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

30608:A2ML1
gene id: 30608:A2ML1
uniprot id: A0A8B7X853
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

30608:LOC105865841
gene id: 30608:LOC105865841
uniprot id: A0A8B7FP89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SEPT3
gene id: 30608:SEPT3
uniprot id: A0A8B7EQG9
uniprot id: A0A8B7EQJ4
uniprot id: A0A8B7ES55
uniprot id: A0A8B7ESK5
uniprot id: A0A8B7X6I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cytoplasm
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

30608:SPEM1
gene id: 30608:SPEM1
uniprot id: A0A8C5UZ28
names: Subcellular Location Annotation
messages: Membrane

30608:EID3
gene id: 30608:EID3
uniprot id: A0A8B7GZ32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus
messages: telomere

30608:NID2
gene id: 30608:NID2
uniprot id: A0A8B7FVU1
uniprot id: A0A8B7FVU4
uniprot id: A0A8B7FW05
uniprot id: A0A8B7FWT9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

30608:PTH
gene id: 30608:PTH
uniprot id: A0A8B7HIS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the parathyroid hormone family.
messages: Interacts with PTH1R (via N-terminal extracellular domain).
messages: PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
messages: Secreted

30608:PCMTD1
gene id: 30608:PCMTD1
uniprot id: A0A8B7I3Z3
uniprot id: A0A8B7I5Y2
uniprot id: A0A8B7I6Z4
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

30608:NFIA
gene id: 30608:NFIA
uniprot id: A0A8B7XA35
uniprot id: A0A8B7XBS9
uniprot id: A0A8B7XC85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

30608:FYN
gene id: 30608:FYN
uniprot id: A0A8B7FJ05
uniprot id: A0A8C5VGD5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

30608:DSG1
gene id: 30608:DSG1
uniprot id: A0A8B7HKJ0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

30608:LAMTOR1
gene id: 30608:LAMTOR1
uniprot id: A0A8B7F058
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

30608:RRH
gene id: 30608:RRH
uniprot id: A0A8B7GGD5
uniprot id: A0A8C5VZD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

30608:LOC105873360
gene id: 30608:LOC105873360
uniprot id: A0A8B7GLJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SH3GLB1
gene id: 30608:SH3GLB1
uniprot id: A0A8B7F5J5
uniprot id: A0A8B7F5J6
uniprot id: A0A8B7F5J8
uniprot id: A0A8B7F5J9
uniprot id: A0A8B7F5K1
uniprot id: A0A8B7F5K4
uniprot id: A0A8B7F5K7
uniprot id: A0A8B7F5L7
uniprot id: A0A8B7F5M2
uniprot id: A0A8C5VQ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Midbody
messages: Mitochondrion outer membrane
messages: autophagosome membrane

30608:LOC105861292
gene id: 30608:LOC105861292
uniprot id: A0A8B7F2K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105858711
gene id: 30608:LOC105858711
uniprot id: A0A8B7EQY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:IREB2
gene id: 30608:IREB2
uniprot id: A0A8C5VB34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Cytoplasm
messages: RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

30608:CENPT
gene id: 30608:CENPT
uniprot id: A0A8B7ES99
uniprot id: A0A8C5V6D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-T/CNN1 family.
messages: Nucleus
messages: kinetochore

30608:COQ7
gene id: 30608:COQ7
uniprot id: A0A8B7EBQ7
uniprot id: A0A8C5V3H9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.
messages: Mitochondrion inner membrane

30608:LOC105879799
gene id: 30608:LOC105879799
uniprot id: A0A8B7HFB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

30608:SYCE1
gene id: 30608:SYCE1
uniprot id: A0A8B7F451
names: Similarity
messages: Belongs to the SYCE family.

30608:MAP3K8
gene id: 30608:MAP3K8
uniprot id: A0A8B7I1L3
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

30608:MANEA
gene id: 30608:MANEA
uniprot id: A0A8C5XBL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:CITED1
gene id: 30608:CITED1
uniprot id: A0A8B7HPR8
uniprot id: A0A8B7HRH0
uniprot id: A0A8C5VL49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

30608:FDPS
gene id: 30608:FDPS
uniprot id: A0A8B7GKM4
uniprot id: A0A8B7GL60
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

30608:MIDN
gene id: 30608:MIDN
uniprot id: A0A8B7F0C7
uniprot id: A0A8B7F0C9
uniprot id: A0A8B7F0E0
uniprot id: A0A8C6EHU7
names: Subcellular Location Annotation
messages: Nucleus

30608:NUDC
gene id: 30608:NUDC
uniprot id: A0A8B7FDA9
uniprot id: A0A8B7WLV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudC family.
messages: Midbody
messages: spindle

30608:OSBPL3
gene id: 30608:OSBPL3
uniprot id: A0A8B7GYQ0
names: Similarity
messages: Belongs to the OSBP family.

30608:KCNK12
gene id: 30608:KCNK12
uniprot id: A0A8B7FRC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

30608:LOC105864697
gene id: 30608:LOC105864697
uniprot id: A0A8B7FI26
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

30608:SKAP1
gene id: 30608:SKAP1
uniprot id: A0A8B7GFG3
uniprot id: A0A8B7GFH5
uniprot id: A0A8B7GFI0
uniprot id: A0A8B7GFY7
uniprot id: A0A8B7GFZ3
uniprot id: A0A8B7GGA1
uniprot id: A0A8B7WMF3
uniprot id: A0A8C5Y3A6
names: Similarity
messages: Belongs to the SKAP family.

30608:LOC105864761
gene id: 30608:LOC105864761
uniprot id: A0A8B7FIE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NSFL1C
gene id: 30608:NSFL1C
uniprot id: A0A8B7FP91
uniprot id: A0A8B7FPI7
names: Subcellular Location Annotation
names: Subunit
messages: Golgi stack
messages: Part of a ternary complex containing STX5A, NSFL1C and VCP. NSFL1C forms a homotrimer that binds to one end of a VCP homohexamer. The complex binds to membranes enriched in phosphatidylethanolamine-containing lipids and promotes Golgi membrane fusion. Interaction with VCIP135 leads to dissociation of the complex via ATP hydrolysis by VCP. Binds ubiquitin and mono-ubiquitinated proteins via its N-terminal UBA-like domain when bound to VCP.

30608:FAM32A
gene id: 30608:FAM32A
uniprot id: A0A8B7FXW4
names: Similarity
messages: Belongs to the FAM32 family.

30608:NDST1
gene id: 30608:NDST1
uniprot id: A0A8B7I8B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

30608:TBC1D7
gene id: 30608:TBC1D7
uniprot id: A0A8B7FK26
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Vesicle

30608:SPC25
gene id: 30608:SPC25
uniprot id: A0A8B7HIZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

30608:CRHR1
gene id: 30608:CRHR1
uniprot id: A0A8B7FE43
uniprot id: A0A8B7FEC6
uniprot id: A0A8B7FF34
uniprot id: A0A8C5VNY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
messages: Membrane

30608:LOC105870798
gene id: 30608:LOC105870798
uniprot id: A0A8B7GAG2
names: Similarity
messages: Belongs to the UFM1 family.

30608:LOC105885870
gene id: 30608:LOC105885870
uniprot id: A0A8C5YFG1
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK. The mature dimeric form interacts with PPP1R16B (via its fourth ankyrin repeat). Interacts with PPP1CA only in the presence of PPP1R16B.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

30608:VPS37C
gene id: 30608:VPS37C
uniprot id: A0A8B7HAP1
uniprot id: A0A8B7HAP3
uniprot id: A0A8C5VS67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

30608:LOC105856163
gene id: 30608:LOC105856163
uniprot id: A0A8B7X310
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Involved in actively transporting phosphate into cells via Na(+) cotransport.
messages: Membrane

30608:USP9X
gene id: 30608:USP9X
uniprot id: A0A8B7HIV2
uniprot id: A0A8B7HIV4
uniprot id: A0A8B7HIW4
uniprot id: A0A8B7HJX4
uniprot id: A0A8B7HLE7
uniprot id: A0A8B7WZ53
uniprot id: A0A8B7WZ56
uniprot id: A0A8B7X062
names: Similarity
messages: Belongs to the peptidase C19 family.

30608:BCAP31
gene id: 30608:BCAP31
uniprot id: A0A8B7FUT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a role in the export of secreted proteins in the ER.

30608:GCNT2
gene id: 30608:GCNT2
uniprot id: A0A8B7FK49
uniprot id: A0A8B7FLI7
uniprot id: A0A8B7WKA1
uniprot id: A0A8C5Y2W2
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

30608:NAA25
gene id: 30608:NAA25
uniprot id: A0A8B7WTG4
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

30608:CACNG7
gene id: 30608:CACNG7
uniprot id: A0A8C5VG53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2.

30608:GGA2
gene id: 30608:GGA2
uniprot id: A0A8B7HF25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

30608:VPS13B
gene id: 30608:VPS13B
uniprot id: A0A8B7G5F7
uniprot id: A0A8B7G5K2
uniprot id: A0A8B7G6R8
names: Similarity
messages: Belongs to the VPS13 family.

30608:LOC109730735
gene id: 30608:LOC109730735
uniprot id: A0A8B7X3Z7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

30608:SLC25A45
gene id: 30608:SLC25A45
uniprot id: A0A8B7H9Y7
uniprot id: A0A8B7H9Z2
uniprot id: A0A8B7H9Z7
uniprot id: A0A8B7HA00
uniprot id: A0A8B7HCQ6
uniprot id: A0A8B7HCR1
uniprot id: A0A8B7HCR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:DNAAF3
gene id: 30608:DNAAF3
uniprot id: A0A8B7H421
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF3 family.
messages: Cytoplasm
messages: Dynein axonemal particle
messages: Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia.

30608:LOC105859339
gene id: 30608:LOC105859339
uniprot id: A0A8B7ETK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

30608:PRPS2
gene id: 30608:PRPS2
uniprot id: A0A8B7HQX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

30608:TMEM129
gene id: 30608:TMEM129
uniprot id: A0A8B7HME8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM129 family.
messages: Membrane

30608:GABRD
gene id: 30608:GABRD
uniprot id: A0A8B7WNK3
uniprot id: A0A8B7WNN2
uniprot id: A0A8B7WPU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:VEGFB
gene id: 30608:VEGFB
uniprot id: A0A8B7H9L0
uniprot id: A0A8C5V856
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

30608:MMD
gene id: 30608:MMD
uniprot id: A0A8B7HI28
uniprot id: A0A8B7HJ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

30608:GMFG
gene id: 30608:GMFG
uniprot id: A0A8B7H1X1
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

30608:TMEM50B
gene id: 30608:TMEM50B
uniprot id: A0A8B7F4D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

30608:ENTPD4
gene id: 30608:ENTPD4
uniprot id: A0A8B7EJR9
uniprot id: A0A8B7EKL1
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

30608:SCGN
gene id: 30608:SCGN
uniprot id: A0A8B7ERI8
names: Subcellular Location Annotation
messages: secretory vesicle membrane

30608:ALDH2
gene id: 30608:ALDH2
uniprot id: A0A8C5V7F1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

30608:LOC105869924
gene id: 30608:LOC105869924
uniprot id: A0A8B7G5R2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:LOC105878952
gene id: 30608:LOC105878952
uniprot id: A0A8B7FEY4
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:GAD2
gene id: 30608:GAD2
uniprot id: A0A8C5XCB6
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

30608:NECAP2
gene id: 30608:NECAP2
uniprot id: A0A8B7G842
uniprot id: A0A8B7G982
uniprot id: A0A8C5VH33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

30608:ASIC1
gene id: 30608:ASIC1
uniprot id: A0A8B7G596
uniprot id: A0A8B7G631
uniprot id: A0A8C5VAM6
names: Subcellular Location Annotation
messages: Membrane

30608:DYNC1H1
gene id: 30608:DYNC1H1
uniprot id: A0A8B7X3N0
names: Similarity
messages: Belongs to the dynein heavy chain family.

30608:C18H4orf48
gene id: 30608:C18H4orf48
uniprot id: A0A8C5XWE9
names: Subcellular Location Annotation
messages: Secreted

30608:FAM92B
gene id: 30608:FAM92B
uniprot id: A0A8B7GBY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIBAR family.
messages: centriole
messages: cilium basal body

30608:LOC105878539
gene id: 30608:LOC105878539
uniprot id: A0A8B7HA40
names: Similarity
messages: Belongs to the GOLGA6 family.

30608:LOC105863115
gene id: 30608:LOC105863115
uniprot id: A0A8B7FB08
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

30608:YARS2
gene id: 30608:YARS2
uniprot id: A0A8B7I217
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

30608:CA11
gene id: 30608:CA11
uniprot id: A0A8C5V6N6
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

30608:RAB32
gene id: 30608:RAB32
uniprot id: A0A8C5UZZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

30608:LOC105859905
gene id: 30608:LOC105859905
uniprot id: A0A8B7EWB9
names: Subcellular Location Annotation
messages: Membrane

30608:DPYS
gene id: 30608:DPYS
uniprot id: A0A8B7HPJ4
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

30608:CCT6B
gene id: 30608:CCT6B
uniprot id: A0A8B7I4B0
uniprot id: A0A8B7I4I5
uniprot id: A0A8B7I4K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

30608:LOC105863109
gene id: 30608:LOC105863109
uniprot id: A0A8B7FB03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CCDC103
gene id: 30608:CCDC103
uniprot id: A0A8B7HVW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC103/PR46b family.
messages: Cytoplasm
messages: Dynein-attachment factor required for cilia motility.
messages: Homodimer.
messages: flagellum

30608:HTRA4
gene id: 30608:HTRA4
uniprot id: A0A8B7WUC9
names: Similarity
messages: Belongs to the peptidase S1C family.

30608:LOC105861182
gene id: 30608:LOC105861182
uniprot id: A0A8B7F2A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

30608:SNRNP200
gene id: 30608:SNRNP200
uniprot id: A0A8B7HYH6
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

30608:SLC25A41
gene id: 30608:SLC25A41
uniprot id: A0A8B7G4N5
uniprot id: A0A8B7WVQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:ERC1
gene id: 30608:ERC1
uniprot id: A0A8B7F4N6
uniprot id: A0A8B7F4N9
uniprot id: A0A8B7F4P0
uniprot id: A0A8B7F4P1
uniprot id: A0A8B7F4P3
uniprot id: A0A8B7F4P4
uniprot id: A0A8B7F4P5
uniprot id: A0A8B7F4P7
uniprot id: A0A8B7F4P8
uniprot id: A0A8B7F4P9
uniprot id: A0A8B7F4Q0
uniprot id: A0A8B7F4Q2
uniprot id: A0A8B7F4Q3
uniprot id: A0A8B7F4Q5
uniprot id: A0A8B7F4Q6
uniprot id: A0A8B7F4Q7
uniprot id: A0A8B7F4R0
uniprot id: A0A8B7F4R3
uniprot id: A0A8B7F4R4
uniprot id: A0A8C5VYD2
uniprot id: A0A8C5XL01
names: Subcellular Location Annotation
messages: Cytoplasm

30608:TMTC3
gene id: 30608:TMTC3
uniprot id: A0A8B7FVH8
uniprot id: A0A8B7FVN5
uniprot id: A0A8B7FWH4
uniprot id: A0A8C5XKW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

30608:GCFC2
gene id: 30608:GCFC2
uniprot id: A0A8B7FUB5
uniprot id: A0A8C5VKJ7
names: Similarity
messages: Belongs to the GCF family.

30608:CPNE8
gene id: 30608:CPNE8
uniprot id: A0A8B7X6C3
names: Similarity
messages: Belongs to the copine family.

30608:C31H21orf59
gene id: 30608:C31H21orf59
uniprot id: A0A8B7HJG0
uniprot id: A0A8C5XYI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP298 family.
messages: cilium basal body

30608:AP3B2
gene id: 30608:AP3B2
uniprot id: A0A8B7G8F5
uniprot id: A0A8B7G8M4
uniprot id: A0A8B7G940
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

30608:JUP
gene id: 30608:JUP
uniprot id: A0A8B7GF94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.
messages: Membrane
messages: adherens junction
messages: desmosome

30608:LOC105870543
gene id: 30608:LOC105870543
uniprot id: A0A8B7G8J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CEP170
gene id: 30608:CEP170
uniprot id: A0A8B7FE94
uniprot id: A0A8B7FE99
uniprot id: A0A8B7FEA4
uniprot id: A0A8B7FEB6
uniprot id: A0A8B7FEC1
uniprot id: A0A8B7FEI3
uniprot id: A0A8B7FEI8
uniprot id: A0A8B7FF94
uniprot id: A0A8B7FF99
uniprot id: A0A8B7FFA5
uniprot id: A0A8C5XDN1
uniprot id: A0A8C5XRD5
names: Similarity
messages: Belongs to the CEP170 family.

30608:ATP7A
gene id: 30608:ATP7A
uniprot id: A0A8B7FQ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

30608:LOC105875531
gene id: 30608:LOC105875531
uniprot id: A0A8B7GX00
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

30608:LOC105874763
gene id: 30608:LOC105874763
uniprot id: A0A8B7X0Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

30608:LOC105886163
gene id: 30608:LOC105886163
uniprot id: A0A8B7I7S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline phosphatase family.
messages: Cell membrane
messages: Membrane

30608:LOC105878827
gene id: 30608:LOC105878827
uniprot id: A0A8B7HB95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105883298
gene id: 30608:LOC105883298
uniprot id: A0A8B7X9K8
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

30608:DDI1
gene id: 30608:DDI1
uniprot id: A0A8B7GS10
names: Similarity
messages: Belongs to the DDI1 family.

30608:KCNH3
gene id: 30608:KCNH3
uniprot id: A0A8B7G469
uniprot id: A0A8C5Y2Y8
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

30608:GREB1
gene id: 30608:GREB1
uniprot id: A0A8B7HH58
uniprot id: A0A8B7HH84
uniprot id: A0A8B7HHX0
uniprot id: A0A8B7HHX6
uniprot id: A0A8B7X9R0
uniprot id: A0A8B7XB27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

30608:HCFC1
gene id: 30608:HCFC1
uniprot id: A0A8B7FU17
uniprot id: A0A8B7FU60
uniprot id: A0A8B7FUU5
uniprot id: A0A8B7FV14
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105880225
gene id: 30608:LOC105880225
uniprot id: A0A8B7HH82
uniprot id: A0A8B7WQ31
uniprot id: A0A8B7WQ34
uniprot id: A0A8B7WQ37
uniprot id: A0A8B7WQ38
uniprot id: A0A8B7WQ39
uniprot id: A0A8B7WQ77
uniprot id: A0A8B7WRI2
uniprot id: A0A8B7WRI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

30608:ADAMTS17
gene id: 30608:ADAMTS17
uniprot id: A0A8B7GBR7
uniprot id: A0A8B7GCR9
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:CHMP5
gene id: 30608:CHMP5
uniprot id: A0A8C5VXG5
names: Similarity
messages: Belongs to the SNF7 family.

30608:VAMP4
gene id: 30608:VAMP4
uniprot id: A0A8B7GDQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

30608:LOC105857945
gene id: 30608:LOC105857945
uniprot id: A0A8B7EMZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SLC45A3
gene id: 30608:SLC45A3
uniprot id: A0A8B7G0L0
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105866638
gene id: 30608:LOC105866638
uniprot id: A0A8B7FRB1
uniprot id: A0A8B7FRV9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:PIR
gene id: 30608:PIR
uniprot id: A0A8B7HQU2
uniprot id: A0A8C5W8E1
names: Similarity
messages: Belongs to the pirin family.

30608:NCOR2
gene id: 30608:NCOR2
uniprot id: A0A8B7WTN4
uniprot id: A0A8B7WTP1
uniprot id: A0A8B7WTP2
uniprot id: A0A8B7WTP7
uniprot id: A0A8B7WTP8
uniprot id: A0A8B7WTQ3
uniprot id: A0A8B7WTQ4
uniprot id: A0A8B7WTQ9
uniprot id: A0A8B7WTV6
uniprot id: A0A8B7WTW7
uniprot id: A0A8B7WTX4
uniprot id: A0A8B7WTZ7
uniprot id: A0A8B7WU05
uniprot id: A0A8B7WU12
uniprot id: A0A8B7WU19
uniprot id: A0A8B7WV92
uniprot id: A0A8B7WV98
uniprot id: A0A8B7WVA4
uniprot id: A0A8B7WVB1
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

30608:NIPAL4
gene id: 30608:NIPAL4
uniprot id: A0A8C5YEM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

30608:ADCY2
gene id: 30608:ADCY2
uniprot id: A0A8B7EWI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

30608:PDE6H
gene id: 30608:PDE6H
uniprot id: A0A8C6EIK4
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

30608:TNFAIP1
gene id: 30608:TNFAIP1
uniprot id: A0A8B7EMN2
names: Similarity
messages: Belongs to the BACURD family.

30608:TM9SF2
gene id: 30608:TM9SF2
uniprot id: A0A8B7FGB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

30608:MOCS2
gene id: 30608:MOCS2
uniprot id: A0A8C5UWV2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MoaE family. MOCS2B subfamily.
messages: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: This protein is produced by a bicistronic gene which also produces the small subunit (MOCS2A) from an overlapping reading frame.
messages: cytosol

30608:RDH14
gene id: 30608:RDH14
uniprot id: A0A8B7FY78
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:INPP5B
gene id: 30608:INPP5B
uniprot id: A0A8B7HEG9
uniprot id: A0A8B7HET2
uniprot id: A0A8B7HH32
uniprot id: A0A8B7HH35
uniprot id: A0A8C6EJN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

30608:MRPL47
gene id: 30608:MRPL47
uniprot id: A0A8B7EDI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Mitochondrion

30608:LOC105859909
gene id: 30608:LOC105859909
uniprot id: A0A8B7EWC2
names: Subcellular Location Annotation
messages: Membrane

30608:MRPL42
gene id: 30608:MRPL42
uniprot id: A0A8C5VEV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL42 family.
messages: Mitochondrion

30608:BTN3A3
gene id: 30608:BTN3A3
uniprot id: A0A8B7XE82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

30608:AGBL3
gene id: 30608:AGBL3
uniprot id: A0A8B7EXP0
uniprot id: A0A8B7XBX4
uniprot id: A0A8B7XBX8
uniprot id: A0A8B7XCW8
uniprot id: A0A8B7XCX4
uniprot id: A0A8B7XDN0
uniprot id: A0A8B7XDN4
uniprot id: A0A8B7XE53
uniprot id: A0A8B7XE57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

30608:DUSP9
gene id: 30608:DUSP9
uniprot id: A0A8B7FU82
uniprot id: A0A8B7FU84
uniprot id: A0A8B7FV25
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

30608:MFAP2
gene id: 30608:MFAP2
uniprot id: A0A8B7G9B0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

30608:CC2D1A
gene id: 30608:CC2D1A
uniprot id: A0A8B7WVP4
uniprot id: A0A8B7WVZ6
uniprot id: A0A8B7WWB4
uniprot id: A0A8B7WXC8
names: Similarity
messages: Belongs to the CC2D1 family.

30608:SOD3
gene id: 30608:SOD3
uniprot id: A0A8B7EF70
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

30608:MFGE8
gene id: 30608:MFGE8
uniprot id: A0A8B7XA59
uniprot id: A0A8B7XA60
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:KIF2A
gene id: 30608:KIF2A
uniprot id: A0A8B7HP07
uniprot id: A0A8B7HP16
uniprot id: A0A8B7HQN6
uniprot id: A0A8B7HRG0
uniprot id: A0A8C5VQP3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

30608:PTAR1
gene id: 30608:PTAR1
uniprot id: A0A8B7EDM5
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

30608:RELN
gene id: 30608:RELN
uniprot id: A0A8B7F3H2
uniprot id: A0A8B7F4C1
uniprot id: A0A8B7F4C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the reelin family.
messages: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Oligomer of disulfide-linked homodimers. Binds to the ectodomains of VLDLR and LRP8/APOER2.
messages: extracellular matrix

30608:LOC105874380
gene id: 30608:LOC105874380
uniprot id: A0A8C5W3W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105870634
gene id: 30608:LOC105870634
uniprot id: A0A8B7G8Q1
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:LOC105863114
gene id: 30608:LOC105863114
uniprot id: A0A8B7FBN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:CORO1B
gene id: 30608:CORO1B
uniprot id: A0A8B7FVP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat coronin family.
messages: Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction.
messages: stress fiber

30608:ATP1A3
gene id: 30608:ATP1A3
uniprot id: A0A8C5VS55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Membrane

30608:LOC105873883
gene id: 30608:LOC105873883
uniprot id: A0A8B7GNF9
names: Similarity
messages: Belongs to the glutaminase family.

30608:THUMPD3
gene id: 30608:THUMPD3
uniprot id: A0A8B7WWU5
names: Similarity
messages: Belongs to the methyltransferase superfamily.

30608:LOC105882208
gene id: 30608:LOC105882208
uniprot id: A0A8B7HRK3
names: Subcellular Location Annotation
messages: Membrane

30608:MKX
gene id: 30608:MKX
uniprot id: A0A8B7GQB6
uniprot id: A0A8C5VEE7
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105881732
gene id: 30608:LOC105881732
uniprot id: A0A8B7WL33
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

30608:LOC105883353
gene id: 30608:LOC105883353
uniprot id: A0A8B7HUW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:ADCY9
gene id: 30608:ADCY9
uniprot id: A0A8B7EV22
uniprot id: A0A8B7WPL8
uniprot id: A0A8B7WQU6
uniprot id: A0A8C5XTQ7
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

30608:EML4
gene id: 30608:EML4
uniprot id: A0A8B7FSR8
uniprot id: A0A8B7FSS5
uniprot id: A0A8B7FST1
uniprot id: A0A8B7FST2
uniprot id: A0A8B7FSU1
uniprot id: A0A8B7FTE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EMAP family.
messages: cytoskeleton

30608:CSTF3
gene id: 30608:CSTF3
uniprot id: A0A8C5VGK9
names: Subcellular Location Annotation
messages: Nucleus

30608:STRIP1
gene id: 30608:STRIP1
uniprot id: A0A8B7FFD9
names: Similarity
messages: Belongs to the STRIP family.

30608:SLC48A1
gene id: 30608:SLC48A1
uniprot id: A0A8B7FKX8
uniprot id: A0A8B7FME0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRG family.
messages: Endosome membrane
messages: Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment.
messages: Lysosome membrane
messages: Membrane

30608:EPS8L3
gene id: 30608:EPS8L3
uniprot id: A0A8B7FFD6
names: Similarity
messages: Belongs to the EPS8 family.

30608:POLR1A
gene id: 30608:POLR1A
uniprot id: A0A8C5W9I5
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

30608:P2RX4
gene id: 30608:P2RX4
uniprot id: A0A8B7WTE9
uniprot id: A0A8B7WTL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

30608:ARHGEF11
gene id: 30608:ARHGEF11
uniprot id: A0A8B7GJL5
uniprot id: A0A8B7GJM0
uniprot id: A0A8B7GJX9
uniprot id: A0A8B7GJY4
uniprot id: A0A8B7GK87
uniprot id: A0A8B7GK91
uniprot id: A0A8B7GKR3
uniprot id: A0A8B7GKS0
uniprot id: A0A8B7WYR0
uniprot id: A0A8B7WYR3
uniprot id: A0A8B7WZ90
uniprot id: A0A8B7WZ94
uniprot id: A0A8B7X0G4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

30608:TMEM41A
gene id: 30608:TMEM41A
uniprot id: A0A8B7FAV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

30608:POMGNT2
gene id: 30608:POMGNT2
uniprot id: A0A8B7GT76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 61 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:FUZ
gene id: 30608:FUZ
uniprot id: A0A8B7FNM2
uniprot id: A0A8C5XFX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fuzzy family.
messages: cytoskeleton

30608:LOC105864005
gene id: 30608:LOC105864005
uniprot id: A0A8B7FFM7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

30608:FAM126A
gene id: 30608:FAM126A
uniprot id: A0A8B7GYL1
uniprot id: A0A8B7GYL7
uniprot id: A0A8B7H0I8
uniprot id: A0A8C5UTW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM126 family.
messages: Cell membrane
messages: Membrane
messages: cytosol

30608:FLAD1
gene id: 30608:FLAD1
uniprot id: A0A8B7GLE2
uniprot id: A0A8C5UY95
names: Function
names: Similarity
messages: Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
messages: In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

30608:LOC105877498
gene id: 30608:LOC105877498
uniprot id: A0A8B7H548
uniprot id: A0A8B7H554
names: Similarity
messages: Belongs to the amidase family.

30608:LOC105868220
gene id: 30608:LOC105868220
uniprot id: A0A8B7FXX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:DAG1
gene id: 30608:DAG1
uniprot id: A0A8B7GTM9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: cytoskeleton
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

30608:NKX2-2
gene id: 30608:NKX2-2
uniprot id: A0A8B7EK82
uniprot id: A0A8C5Y473
names: Subcellular Location Annotation
messages: Nucleus

30608:DMRTB1
gene id: 30608:DMRTB1
uniprot id: A0A8B7H5Q6
uniprot id: A0A8B7H828
uniprot id: A0A8B7XCH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

30608:HRH2
gene id: 30608:HRH2
uniprot id: A0A8C5Y464
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SULT1E1
gene id: 30608:SULT1E1
uniprot id: A0A8B7HTN1
uniprot id: A0A8C5YFE3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

30608:CHRNB2
gene id: 30608:CHRNB2
uniprot id: A0A8B7GKB1
uniprot id: A0A8C5VY82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

30608:NUDT19
gene id: 30608:NUDT19
uniprot id: A0A8B7H321
names: Similarity
messages: Belongs to the Nudix hydrolase family.

30608:DLX6
gene id: 30608:DLX6
uniprot id: A0A8B7FUL9
names: Subcellular Location Annotation
messages: Nucleus

30608:APH1A
gene id: 30608:APH1A
uniprot id: A0A8B7GK66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

30608:PRDM16
gene id: 30608:PRDM16
uniprot id: A0A8B7H4F5
uniprot id: A0A8B7H4J3
uniprot id: A0A8B7H6P4
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105863650
gene id: 30608:LOC105863650
uniprot id: A0A8B7FE33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

30608:MAST1
gene id: 30608:MAST1
uniprot id: A0A8B7WWG0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

30608:PLXND1
gene id: 30608:PLXND1
uniprot id: A0A8B7HUF3
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:LOC105861330
gene id: 30608:LOC105861330
uniprot id: A0A8B7F3V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105855594
gene id: 30608:LOC105855594
uniprot id: A0A8B7ED97
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

30608:LOC105868763
gene id: 30608:LOC105868763
uniprot id: A0A8B7G0C1
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

30608:SLC4A5
gene id: 30608:SLC4A5
uniprot id: A0A8B7I0J3
uniprot id: A0A8B7I2N7
uniprot id: A0A8B7X264
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

30608:UNC5C
gene id: 30608:UNC5C
uniprot id: A0A8B7WXZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

30608:LOC105858732
gene id: 30608:LOC105858732
uniprot id: A0A8B7ET00
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:FLT4
gene id: 30608:FLT4
uniprot id: A0A8B7FMX4
uniprot id: A0A8B7WRD6
uniprot id: A0A8B7WRE4
uniprot id: A0A8B7WRE8
uniprot id: A0A8B7WRF3
uniprot id: A0A8B7WRG6
uniprot id: A0A8B7WRH1
uniprot id: A0A8B7WSV1
uniprot id: A0A8B7WSV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Nucleus

30608:ART1
gene id: 30608:ART1
uniprot id: A0A8B7EYH3
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

30608:XPOT
gene id: 30608:XPOT
uniprot id: A0A8B7HLB9
uniprot id: A0A8B7HMP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

30608:G6PC2
gene id: 30608:G6PC2
uniprot id: A0A8C5Y7G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

30608:ATP5L
gene id: 30608:ATP5L
uniprot id: A0A8B7H190
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

30608:ITGB1
gene id: 30608:ITGB1
uniprot id: A0A8B7ELT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Cell surface
messages: Melanosome
messages: Membrane
messages: Recycling endosome
messages: focal adhesion
messages: invadopodium membrane
messages: lamellipodium
messages: ruffle membrane

30608:NCBP2
gene id: 30608:NCBP2
uniprot id: A0A8B7HFD0
uniprot id: A0A8B7HFD1
uniprot id: A0A8B7HFG2
uniprot id: A0A8B7HI18
uniprot id: A0A8C5YIH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus

30608:PARPBP
gene id: 30608:PARPBP
uniprot id: A0A8B7GX15
uniprot id: A0A8B7GX37
uniprot id: A0A8B7GX39
uniprot id: A0A8B7GYX9
uniprot id: A0A8B7X8S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PARI family.
messages: Cytoplasm
messages: Nucleus

30608:ITIH1
gene id: 30608:ITIH1
uniprot id: A0A8B7GUB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

30608:CDK9
gene id: 30608:CDK9
uniprot id: A0A8B7GVG7
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:CDKL4
gene id: 30608:CDKL4
uniprot id: A0A8B7X8W0
uniprot id: A0A8B7X8W1
uniprot id: A0A8B7X9K7
uniprot id: A0A8B7XAI9
uniprot id: A0A8B7XAX2
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:LOC105883402
gene id: 30608:LOC105883402
uniprot id: A0A8B7HX62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:HEATR5B
gene id: 30608:HEATR5B
uniprot id: A0A8B7I021
uniprot id: A0A8B7I023
uniprot id: A0A8B7I255
uniprot id: A0A8B7I2R8
names: Similarity
messages: Belongs to the HEATR5 family.

30608:LOC105864468
gene id: 30608:LOC105864468
uniprot id: A0A8B7FH59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PRR15L
gene id: 30608:PRR15L
uniprot id: A0A8B7GG82
names: Similarity
messages: Belongs to the PRR15 family.

30608:ACTG2
gene id: 30608:ACTG2
uniprot id: A0A8C5W9U8
names: Similarity
messages: Belongs to the actin family.

30608:LOC105879758
gene id: 30608:LOC105879758
uniprot id: A0A8B7X9Y7
uniprot id: A0A8B7X9Z3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Monomer.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

30608:LOC105868729
gene id: 30608:LOC105868729
uniprot id: A0A8B7G084
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105866512
gene id: 30608:LOC105866512
uniprot id: A0A8B7FQP4
names: Subcellular Location Annotation
messages: Membrane

30608:B3GNT5
gene id: 30608:B3GNT5
uniprot id: A0A8B7X2X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:AGPAT4
gene id: 30608:AGPAT4
uniprot id: A0A8B7G0Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Endoplasmic reticulum membrane

30608:NOG
gene id: 30608:NOG
uniprot id: A0A8C5XIV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.
messages: Secreted

30608:MINOS1
gene id: 30608:MINOS1
uniprot id: A0A8B7HY42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

30608:BCL2A1
gene id: 30608:BCL2A1
uniprot id: A0A8B7FH37
names: Similarity
messages: Belongs to the Bcl-2 family.

30608:KHDRBS3
gene id: 30608:KHDRBS3
uniprot id: A0A8B7XA20
uniprot id: A0A8B7XA21
uniprot id: A0A8B7XAT4
uniprot id: A0A8B7XC71
names: Similarity
messages: Belongs to the KHDRBS family.

30608:ACY1
gene id: 30608:ACY1
uniprot id: A0A8B7GVX3
uniprot id: A0A8C5XLZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Cytoplasm

30608:ODF2L
gene id: 30608:ODF2L
uniprot id: A0A8B7F5I7
uniprot id: A0A8B7F5K8
uniprot id: A0A8B7F5L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

30608:MYO3A
gene id: 30608:MYO3A
uniprot id: A0A8B7H876
uniprot id: A0A8B7H881
uniprot id: A0A8B7WWA6
uniprot id: A0A8B7WWL8
uniprot id: A0A8B7WX19
uniprot id: A0A8B7WY07
uniprot id: A0A8C5Y228
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: In the C-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

30608:SELENOI
gene id: 30608:SELENOI
uniprot id: A0A8B7I220
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

30608:LOC109730285
gene id: 30608:LOC109730285
uniprot id: A0A8B7WZY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

30608:IL6R
gene id: 30608:IL6R
uniprot id: A0A8C5Y3L5
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 3 subfamily.

30608:LOC105865739
gene id: 30608:LOC105865739
uniprot id: A0A8B7X8D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

30608:TMEM8A
gene id: 30608:TMEM8A
uniprot id: A0A8B7EFG4
uniprot id: A0A8B7EI00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

30608:RDH11
gene id: 30608:RDH11
uniprot id: A0A8B7HH95
uniprot id: A0A8B7HHC4
uniprot id: A0A8B7HI17
uniprot id: A0A8B7HJW5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:FXYD1
gene id: 30608:FXYD1
uniprot id: A0A8B7H4Z2
names: Similarity
messages: Belongs to the FXYD family.

30608:NOX4
gene id: 30608:NOX4
uniprot id: A0A8B7X3X7
names: Subcellular Location Annotation
messages: Membrane

30608:JAKMIP1
gene id: 30608:JAKMIP1
uniprot id: A0A8B7EKB5
uniprot id: A0A8B7EKB7
uniprot id: A0A8B7ELK7
uniprot id: A0A8B7WVH6
names: Similarity
messages: Belongs to the JAKMIP family.

30608:EEF2KMT
gene id: 30608:EEF2KMT
uniprot id: A0A8B7WQS7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EEF2KMT family.

30608:LOC105881944
gene id: 30608:LOC105881944
uniprot id: A0A8B7HR83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TBX19
gene id: 30608:TBX19
uniprot id: A0A8B7HNN3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

30608:CLDN25
gene id: 30608:CLDN25
uniprot id: A0A8B7FJI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

30608:ATP5J
gene id: 30608:ATP5J
uniprot id: A0A8B7GBX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

30608:LOC105858588
gene id: 30608:LOC105858588
uniprot id: A0A8B7X6J0
uniprot id: A0A8B7X6J4
uniprot id: A0A8B7X786
uniprot id: A0A8B7X893
uniprot id: A0A8B7X898
uniprot id: A0A8B7X8I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

30608:GPR171
gene id: 30608:GPR171
uniprot id: A0A8B7HMK4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:PDE4C
gene id: 30608:PDE4C
uniprot id: A0A8B7WW13
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

30608:LOC105883498
gene id: 30608:LOC105883498
uniprot id: A0A8B7HVH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:RUNX1T1
gene id: 30608:RUNX1T1
uniprot id: A0A8B7FAE8
uniprot id: A0A8B7FAF1
uniprot id: A0A8B7FAK6
uniprot id: A0A8B7FB13
uniprot id: A0A8C5XJS4
names: Similarity
messages: Belongs to the CBFA2T family.

30608:TDRD9
gene id: 30608:TDRD9
uniprot id: A0A8B7F229
uniprot id: A0A8B7F231
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily.

30608:SFMBT2
gene id: 30608:SFMBT2
uniprot id: A0A8B7ER47
names: Subcellular Location Annotation
messages: Nucleus

30608:MEP1A
gene id: 30608:MEP1A
uniprot id: A0A8B7X5B1
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:TINAG
gene id: 30608:TINAG
uniprot id: A0A8B7X6G6
uniprot id: A0A8C5VHW8
names: Similarity
messages: Belongs to the peptidase C1 family.

30608:NEU3
gene id: 30608:NEU3
uniprot id: A0A8B7EYR5
uniprot id: A0A8B7F0I5
uniprot id: A0A8B7F0V9
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

30608:TMEM86A
gene id: 30608:TMEM86A
uniprot id: A0A8B7HGV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

30608:AMFR
gene id: 30608:AMFR
uniprot id: A0A8C5XHE8
names: Subcellular Location Annotation
messages: Membrane

30608:SLC16A13
gene id: 30608:SLC16A13
uniprot id: A0A8B7H802
uniprot id: A0A8B7HAN2
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105862687
gene id: 30608:LOC105862687
uniprot id: A0A8B7F9E8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:CDS2
gene id: 30608:CDS2
uniprot id: A0A8B7FP96
uniprot id: A0A8C5VCX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

30608:LOC105873298
gene id: 30608:LOC105873298
uniprot id: A0A8B7GKP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

30608:LOC105882998
gene id: 30608:LOC105882998
uniprot id: A0A8B7HVG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

30608:DDB2
gene id: 30608:DDB2
uniprot id: A0A8B7I1X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Nucleus

30608:PPOX
gene id: 30608:PPOX
uniprot id: A0A8B7GLU3
uniprot id: A0A8B7GMD9
uniprot id: A0A8C5UX90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

30608:HSBP1L1
gene id: 30608:HSBP1L1
uniprot id: A0A8B7WRH8
uniprot id: A0A8B7WRJ5
names: Similarity
messages: Belongs to the HSBP1 family.

30608:YY1
gene id: 30608:YY1
uniprot id: A0A8B7F4H5
names: Similarity
messages: Belongs to the YY transcription factor family.

30608:RRP1
gene id: 30608:RRP1
uniprot id: A0A8B7HF29
names: Similarity
messages: Belongs to the RRP1 family.

30608:UBE2E3
gene id: 30608:UBE2E3
uniprot id: A0A8C6EKC5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

30608:MYO10
gene id: 30608:MYO10
uniprot id: A0A8B7XDW9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

30608:SLC6A19
gene id: 30608:SLC6A19
uniprot id: A0A8B7H0J9
uniprot id: A0A8B7H0R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

30608:LOC105864414
gene id: 30608:LOC105864414
uniprot id: A0A8B7FH33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:RPL22
gene id: 30608:RPL22
uniprot id: A0A8B7I7R2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

30608:LOC105883404
gene id: 30608:LOC105883404
uniprot id: A0A8B7HV18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:FTH1
gene id: 30608:FTH1
uniprot id: A0A8B7HAH7
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

30608:SLC52A3
gene id: 30608:SLC52A3
uniprot id: A0A8B7FQ01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

30608:LOC105883363
gene id: 30608:LOC105883363
uniprot id: A0A8B7HX26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MON1A
gene id: 30608:MON1A
uniprot id: A0A8B7WKZ2
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

30608:PENK
gene id: 30608:PENK
uniprot id: A0A8B7H0H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Increases glutamate release in the striatum and decreases GABA concentration in the striatum.
messages: Neuropeptide that competes with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Secreted
messages: chromaffin granule lumen

30608:S100A5
gene id: 30608:S100A5
uniprot id: A0A8B7I6V7
names: Similarity
messages: Belongs to the S-100 family.

30608:LOC105863143
gene id: 30608:LOC105863143
uniprot id: A0A8B7FB58
uniprot id: A0A8B7FB59
uniprot id: A0A8B7FB79
uniprot id: A0A8B7FBC0
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

30608:LOC105861733
gene id: 30608:LOC105861733
uniprot id: A0A8B7F5F7
uniprot id: A0A8B7F5G4
uniprot id: A0A8B7F5H5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.

30608:HOXB1
gene id: 30608:HOXB1
uniprot id: A0A8B7GFG8
uniprot id: A0A8B7GGA7
uniprot id: A0A8C5XX31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Labial subfamily.
messages: Nucleus

30608:PRDM10
gene id: 30608:PRDM10
uniprot id: A0A8B7HMB0
uniprot id: A0A8B7HMC0
uniprot id: A0A8B7HMC2
uniprot id: A0A8B7HNS8
uniprot id: A0A8B7HPT7
uniprot id: A0A8C5WAB9
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

30608:LOC105858291
gene id: 30608:LOC105858291
uniprot id: A0A8B7EP58
uniprot id: A0A8B7EPB0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

30608:LOC105881121
gene id: 30608:LOC105881121
uniprot id: A0A8C5V739
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

30608:LOC105868098
gene id: 30608:LOC105868098
uniprot id: A0A8B7FYG4
names: Subcellular Location Annotation
messages: Nucleus

30608:HOXA1
gene id: 30608:HOXA1
uniprot id: A0A8C5YBP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Labial subfamily.
messages: Nucleus

30608:LOC105874212
gene id: 30608:LOC105874212
uniprot id: A0A8B7GQ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

30608:DYNC2H1
gene id: 30608:DYNC2H1
uniprot id: A0A8B7X3Y6
names: Similarity
messages: Belongs to the dynein heavy chain family.

30608:TYW3
gene id: 30608:TYW3
uniprot id: A0A8C5W6N5
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

30608:ELK3
gene id: 30608:ELK3
uniprot id: A0A8C5VJZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:ATP6V1B2
gene id: 30608:ATP6V1B2
uniprot id: A0A8B7HRL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

30608:RRM1
gene id: 30608:RRM1
uniprot id: A0A8B7EY63
uniprot id: A0A8B7EY64
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

30608:SHMT1
gene id: 30608:SHMT1
uniprot id: A0A8B7F6G2
uniprot id: A0A8C5VR56
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

30608:POMGNT1
gene id: 30608:POMGNT1
uniprot id: A0A8B7X8N5
names: Subcellular Location Annotation
messages: Golgi apparatus membrane

30608:FAM214B
gene id: 30608:FAM214B
uniprot id: A0A8B7GQM0
uniprot id: A0A8B7GQN3
names: Similarity
messages: Belongs to the FAM214 family.

30608:FARSB
gene id: 30608:FARSB
uniprot id: A0A8B7ESU4
uniprot id: A0A8C5YDM7
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

30608:RBM5
gene id: 30608:RBM5
uniprot id: A0A8B7GTZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBM5/RBM10 family.
messages: Nucleus

30608:LOC109731316
gene id: 30608:LOC109731316
uniprot id: A0A8B7XEP8
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6c family.

30608:LOC105867974
gene id: 30608:LOC105867974
uniprot id: A0A8B7WXG2
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:SLC25A36
gene id: 30608:SLC25A36
uniprot id: A0A8C5YHK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:NBR1
gene id: 30608:NBR1
uniprot id: A0A8B7EU01
uniprot id: A0A8B7EVY8
names: Subcellular Location Annotation
messages: Lysosome
messages: autophagosome

30608:PPP1R35
gene id: 30608:PPP1R35
uniprot id: A0A8B7FZ40
uniprot id: A0A8B7FZ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP1R35 family.
messages: centriole

30608:CACNG3
gene id: 30608:CACNG3
uniprot id: A0A8B7HF22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

30608:PTGER4
gene id: 30608:PTGER4
uniprot id: A0A8B7H988
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

30608:MCPH1
gene id: 30608:MCPH1
uniprot id: A0A8B7HM35
uniprot id: A0A8B7HM37
uniprot id: A0A8B7HM38
uniprot id: A0A8B7HNI3
uniprot id: A0A8B7WSL5
uniprot id: A0A8B7WSU3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex.
messages: Interacts with CDC27 and maybe other components of the APC/C complex. Interacts with histone variant H2AX under DNA damage conditions.
messages: centrosome

30608:LOC105879907
gene id: 30608:LOC105879907
uniprot id: A0A8B7HGK0
names: Function
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

30608:TOMM20L
gene id: 30608:TOMM20L
uniprot id: A0A8C5Y5C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

30608:MIGA2
gene id: 30608:MIGA2
uniprot id: A0A8B7GVW9
uniprot id: A0A8B7GW12
names: Similarity
messages: Belongs to the mitoguardin family.

30608:EBF3
gene id: 30608:EBF3
uniprot id: A0A8B7HHX5
uniprot id: A0A8B7HHY1
uniprot id: A0A8B7HHY7
uniprot id: A0A8B7HI04
uniprot id: A0A8B7HI10
uniprot id: A0A8B7HIV3
uniprot id: A0A8B7HIV7
uniprot id: A0A8B7HKI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

30608:FOXN4
gene id: 30608:FOXN4
uniprot id: A0A8B7FSV3
names: Subcellular Location Annotation
messages: Nucleus

30608:TRPM7
gene id: 30608:TRPM7
uniprot id: A0A8B7G9V6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
messages: Membrane

30608:LOC105867545
gene id: 30608:LOC105867545
uniprot id: A0A8B7FV87
uniprot id: A0A8B7FVF2
names: Similarity
messages: Belongs to the actin family.

30608:CENPV
gene id: 30608:CENPV
uniprot id: A0A8B7WNH9
uniprot id: A0A8B7WNK7
names: Similarity
messages: Belongs to the Gfa family.

30608:LHX6
gene id: 30608:LHX6
uniprot id: A0A8B7GUU6
uniprot id: A0A8B7GUV1
uniprot id: A0A8B7GUX6
uniprot id: A0A8B7GV00
uniprot id: A0A8B7GV07
uniprot id: A0A8B7GWL7
uniprot id: A0A8B7XB94
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105864699
gene id: 30608:LOC105864699
uniprot id: W0UUW9
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

30608:MRPS14
gene id: 30608:MRPS14
uniprot id: A0A8B7GDN2
uniprot id: A0A8C5VEL6
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

30608:APPL1
gene id: 30608:APPL1
uniprot id: A0A8B7WL52
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Nucleus
messages: phagosome
messages: ruffle

30608:KRT79
gene id: 30608:KRT79
uniprot id: A0A8B7G8J5
names: Similarity
messages: Belongs to the intermediate filament family.

30608:LOC105884144
gene id: 30608:LOC105884144
uniprot id: A0A8B7I182
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:COPS8
gene id: 30608:COPS8
uniprot id: A0A8B7FQE0
uniprot id: A0A8C5VH39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN8 family.
messages: Cytoplasm
messages: Nucleus

30608:LOC105861736
gene id: 30608:LOC105861736
uniprot id: A0A8B7F5G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

30608:TMEM159
gene id: 30608:TMEM159
uniprot id: A0A8B7I491
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDAF1 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Membrane

30608:ASB18
gene id: 30608:ASB18
uniprot id: A0A8B7FMS7
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

30608:C14H4orf47
gene id: 30608:C14H4orf47
uniprot id: A0A8B7HR81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0602 family.
messages: centrosome

30608:SMS
gene id: 30608:SMS
uniprot id: A0A8B7HST5
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

30608:LOC105872416
gene id: 30608:LOC105872416
uniprot id: A0A8B7GH42
uniprot id: A0A8B7GH47
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:LOC105864473
gene id: 30608:LOC105864473
uniprot id: A0A8B7FH71
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105873314
gene id: 30608:LOC105873314
uniprot id: A0A8B7GKR6
uniprot id: A0A8B7GL30
uniprot id: A0A8B7XBU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:COL4A6
gene id: 30608:COL4A6
uniprot id: A0A8B7FCI5
uniprot id: A0A8B7FCI7
uniprot id: A0A8B7FCJ2
uniprot id: A0A8B7FCJ9
uniprot id: A0A8B7FCL8
uniprot id: A0A8B7FCQ5
uniprot id: A0A8B7FDE6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

30608:RHBDF2
gene id: 30608:RHBDF2
uniprot id: A0A8C5XJ50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

30608:CCNO
gene id: 30608:CCNO
uniprot id: A0A8C5V3T7
names: Similarity
messages: Belongs to the cyclin family.

30608:LOC105878358
gene id: 30608:LOC105878358
uniprot id: A0A8B7HBV8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

30608:USP21
gene id: 30608:USP21
uniprot id: A0A8B7GLU6
uniprot id: A0A8B7GM62
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

30608:SPTBN2
gene id: 30608:SPTBN2
uniprot id: A0A8B7FUP4
uniprot id: A0A8B7FVQ0
names: Similarity
messages: Belongs to the spectrin family.

30608:SERPINA5
gene id: 30608:SERPINA5
uniprot id: A0A8C5V477
names: Similarity
messages: Belongs to the serpin family.

30608:ISM1
gene id: 30608:ISM1
uniprot id: A0A8C5W4G0
names: Similarity
messages: Belongs to the isthmin family.

30608:IPO8
gene id: 30608:IPO8
uniprot id: A0A8C5XM85
names: Subcellular Location Annotation
messages: Cytoplasm

30608:CBR4
gene id: 30608:CBR4
uniprot id: A0A8B7GSC4
uniprot id: A0A8B7GTQ8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:LIPC
gene id: 30608:LIPC
uniprot id: A0A8B7X300
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:MYO6
gene id: 30608:MYO6
uniprot id: A0A8B7ETT3
uniprot id: A0A8B7ETT4
uniprot id: A0A8B7ETT7
uniprot id: A0A8B7EVQ6
uniprot id: A0A8B7EVT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: clathrin-coated pit
messages: clathrin-coated vesicle
messages: filopodium
messages: microvillus

30608:ACKR1
gene id: 30608:ACKR1
uniprot id: A0A8C5W4X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1 and TARC. May regulate chemokine bioavailability and, consequently, leukocyte recruitment through two distinct mechanisms: when expressed in endothelial cells, it sustains the abluminal to luminal transcytosis of tissue-derived chemokines and their subsequent presentation to circulating leukocytes; when expressed in erythrocytes, serves as blood reservoir of cognate chemokines but also as a chemokine sink, buffering potential surges in plasma chemokine levels.
messages: Belongs to the G-protein coupled receptor 1 family. Atypical chemokine receptor subfamily.
messages: Early endosome
messages: Membrane
messages: Recycling endosome

30608:DNAJA4
gene id: 30608:DNAJA4
uniprot id: A0A8B7ELZ3
names: Subcellular Location Annotation
messages: Membrane

30608:RXFP4
gene id: 30608:RXFP4
uniprot id: A0A8B7X047
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:EHD3
gene id: 30608:EHD3
uniprot id: A0A8B7I2L0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: cilium membrane

30608:LOC105861980
gene id: 30608:LOC105861980
uniprot id: A0A8C5Y4J8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

30608:SPTBN1
gene id: 30608:SPTBN1
uniprot id: A0A8B7H9B4
uniprot id: A0A8B7HC26
uniprot id: A0A8C5XSZ5
uniprot id: A0A8C5YA37
names: Similarity
messages: Belongs to the spectrin family.

30608:PAX2
gene id: 30608:PAX2
uniprot id: A0A8B7GMG0
uniprot id: A0A8B7GMJ4
uniprot id: A0A8B7GMQ1
uniprot id: A0A8B7GMQ4
uniprot id: A0A8B7GMV9
uniprot id: A0A8B7GMW8
uniprot id: A0A8B7GMX7
uniprot id: A0A8B7GMZ2
uniprot id: A0A8B7GN56
uniprot id: A0A8B7WLS0
uniprot id: A0A8B7WLT0
uniprot id: A0A8B7WLV0
uniprot id: A0A8B7WMT2
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105865915
gene id: 30608:LOC105865915
uniprot id: A0A8B7FNF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:AQP9
gene id: 30608:AQP9
uniprot id: A0A8B7X3H6
uniprot id: A0A8C5VTJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

30608:MICAL3
gene id: 30608:MICAL3
uniprot id: A0A8B7F5Y4
uniprot id: A0A8B7F5Y7
uniprot id: A0A8B7F5Z0
uniprot id: A0A8B7F5Z1
uniprot id: A0A8B7F5Z3
uniprot id: A0A8B7F5Z5
uniprot id: A0A8B7F5Z6
uniprot id: A0A8B7F5Z7
uniprot id: A0A8B7F5Z9
uniprot id: A0A8B7F600
uniprot id: A0A8B7F601
uniprot id: A0A8B7F603
uniprot id: A0A8B7F609
uniprot id: A0A8B7F613
uniprot id: A0A8B7F618
uniprot id: A0A8B7F625
uniprot id: A0A8B7F633
uniprot id: A0A8B7X5I8
uniprot id: A0A8B7X5J1
uniprot id: A0A8B7X7I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Nucleus
messages: cytoskeleton

30608:GDI1
gene id: 30608:GDI1
uniprot id: A0A8C5XGU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

30608:LOC105884957
gene id: 30608:LOC105884957
uniprot id: A0A8B7I2H4
uniprot id: A0A8B7X2Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOG/XMAP215 family.
messages: kinetochore

30608:TAS2R1
gene id: 30608:TAS2R1
uniprot id: A0A8B7I6P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

30608:SSPO
gene id: 30608:SSPO
uniprot id: A0A8B7HTV8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

30608:ZDHHC24
gene id: 30608:ZDHHC24
uniprot id: A0A8B7FVR6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

30608:TFDP2
gene id: 30608:TFDP2
uniprot id: A0A8B7G692
uniprot id: A0A8B7G701
uniprot id: A0A8B7G7H1
uniprot id: A0A8B7X1I6
uniprot id: A0A8B7X1K9
uniprot id: A0A8B7X215
uniprot id: A0A8B7X226
uniprot id: A0A8B7X2S3
uniprot id: A0A8B7X3A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

30608:C1S
gene id: 30608:C1S
uniprot id: A0A8C5W221
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:SSTR2
gene id: 30608:SSTR2
uniprot id: A0A8B7FRL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

30608:UNC13B
gene id: 30608:UNC13B
uniprot id: A0A8B7GQJ8
uniprot id: A0A8B7GQK2
uniprot id: A0A8B7GQK5
uniprot id: A0A8B7GQT8
uniprot id: A0A8B7GQU3
uniprot id: A0A8B7GQU8
uniprot id: A0A8B7GQY8
uniprot id: A0A8B7GQZ3
uniprot id: A0A8B7GS46
uniprot id: A0A8B7GS53
uniprot id: A0A8B7XB25
uniprot id: A0A8B7XB30
uniprot id: A0A8B7XBW3
uniprot id: A0A8B7XCR7
uniprot id: A0A8B7XD86
uniprot id: A0A8B7XD94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-13 family.
messages: Cytoplasm
messages: Membrane

30608:GJD3
gene id: 30608:GJD3
uniprot id: A0A8B7GFS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

30608:TTC19
gene id: 30608:TTC19
uniprot id: A0A8B7EFS8
uniprot id: A0A8B7EG97
uniprot id: A0A8B7EGL9
uniprot id: A0A8B7EI99
names: Similarity
messages: Belongs to the TTC19 family.

30608:ESX1
gene id: 30608:ESX1
uniprot id: A0A8B7HZ02
names: Subcellular Location Annotation
messages: Nucleus

30608:GAREM2
gene id: 30608:GAREM2
uniprot id: A0A8B7I203
names: Similarity
messages: Belongs to the GAREM family.

30608:SARS
gene id: 30608:SARS
uniprot id: A0A8B7FF91
uniprot id: A0A8B7FFH2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

30608:LOC105879940
gene id: 30608:LOC105879940
uniprot id: A0A8B7HGS6
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

30608:ANKLE2
gene id: 30608:ANKLE2
uniprot id: A0A8B7F5Q9
uniprot id: A0A8B7F5R4
uniprot id: A0A8B7F5S9
names: Similarity
messages: Belongs to the ANKLE2 family.

30608:MARK4
gene id: 30608:MARK4
uniprot id: A0A8B7G3Z0
uniprot id: A0A8C5VJN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

30608:PANX3
gene id: 30608:PANX3
uniprot id: A0A8C5XSV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

30608:ZNF75D
gene id: 30608:ZNF75D
uniprot id: A0A8B7WZE4
names: Subcellular Location Annotation
messages: Nucleus

30608:TLE1
gene id: 30608:TLE1
uniprot id: A0A8B7EBN2
uniprot id: A0A8B7EC17
uniprot id: A0A8B7ECB0
uniprot id: A0A8C5VEI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

30608:LOC105864417
gene id: 30608:LOC105864417
uniprot id: A0A8B7FH06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NCOA7
gene id: 30608:NCOA7
uniprot id: A0A8B7H8J4
uniprot id: A0A8B7H8K0
uniprot id: A0A8B7H8K2
uniprot id: A0A8B7H8K5
uniprot id: A0A8B7H8K6
uniprot id: A0A8B7H8L1
uniprot id: A0A8B7HB69
uniprot id: A0A8B7X5H7
uniprot id: A0A8B7X6M5
uniprot id: A0A8C5VGN1
names: Similarity
messages: Belongs to the OXR1 family.

30608:LOC105869686
gene id: 30608:LOC105869686
uniprot id: A0A8B7G5K0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:RABEP1
gene id: 30608:RABEP1
uniprot id: A0A8C5YDC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Cytoplasm
messages: Early endosome
messages: Endosome

30608:PROSC
gene id: 30608:PROSC
uniprot id: A0A8B7G7Z7
uniprot id: A0A8B7G8H1
uniprot id: A0A8B7G8W9
names: Caution
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

30608:STK17B
gene id: 30608:STK17B
uniprot id: A0A8C5XE49
names: Similarity
messages: Belongs to the protein kinase superfamily.

30608:GRM2
gene id: 30608:GRM2
uniprot id: A0A8B7GU74
uniprot id: A0A8B7GU96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

30608:POT1
gene id: 30608:POT1
uniprot id: A0A8C5VMK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the telombin family.
messages: Nucleus
messages: telomere

30608:APEH
gene id: 30608:APEH
uniprot id: A0A8B7GTN8
uniprot id: A0A8B7GTU4
uniprot id: A0A8B7GTW4
uniprot id: A0A8B7GVF9
uniprot id: A0A8C5UXC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S9C family.
messages: Cytoplasm
messages: Homotetramer.
messages: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.

30608:CLDN7
gene id: 30608:CLDN7
uniprot id: A0A8C5Y660
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

30608:CADM2
gene id: 30608:CADM2
uniprot id: A0A8B7EN72
uniprot id: A0A8B7END6
uniprot id: A0A8B7EQE3
names: Similarity
messages: Belongs to the nectin family.

30608:KRT78
gene id: 30608:KRT78
uniprot id: A0A8C5XH21
names: Similarity
messages: Belongs to the intermediate filament family.

30608:LOC105868328
gene id: 30608:LOC105868328
uniprot id: A0A8C5XYQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

30608:LOC105855895
gene id: 30608:LOC105855895
uniprot id: A0A8B7WSR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTU2/NCS2 family.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

30608:MMP28
gene id: 30608:MMP28
uniprot id: A0A8B7HTP4
uniprot id: A0A8B7HU47
names: Similarity
messages: Belongs to the peptidase M10A family.

30608:RAD51
gene id: 30608:RAD51
uniprot id: A0A8B7GH89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Also involved in interstrand cross-link repair.

30608:TPT1
gene id: 30608:TPT1
uniprot id: A0A8B7HKW6
names: Similarity
messages: Belongs to the TCTP family.

30608:TMEM173
gene id: 30608:TMEM173
uniprot id: A0A8B7F981
uniprot id: A0A8C5VPA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STING family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: autophagosome membrane
messages: perinuclear region

30608:RTFDC1
gene id: 30608:RTFDC1
uniprot id: A0A8C5W7P7
names: Similarity
names: Subunit
messages: Belongs to the rtf2 family.
messages: Interacts with DDI2; probably also interacts with DDI1.

30608:MGAT5
gene id: 30608:MGAT5
uniprot id: A0A8B7EMG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Secreted

30608:PIK3R2
gene id: 30608:PIK3R2
uniprot id: A0A8B7WW11
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

30608:DVL2
gene id: 30608:DVL2
uniprot id: A0A8B7H7I0
uniprot id: A0A8B7H7J5
names: Similarity
messages: Belongs to the DSH family.

30608:RPS27
gene id: 30608:RPS27
uniprot id: A0A8C5UWF2
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

30608:LOC105879238
gene id: 30608:LOC105879238
uniprot id: A0A8B7HD74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SHOX2
gene id: 30608:SHOX2
uniprot id: A0A8B7EKG9
uniprot id: A0A8B7ELR5
uniprot id: A0A8B7EMS9
names: Subcellular Location Annotation
messages: Nucleus

30608:EPHA1
gene id: 30608:EPHA1
uniprot id: A0A8B7GKQ0
uniprot id: A0A8B7GLB9
names: Subcellular Location Annotation
messages: Membrane

30608:CAPN1
gene id: 30608:CAPN1
uniprot id: A0A8B7H9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C2 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

30608:IL25
gene id: 30608:IL25
uniprot id: A0A8B7FHY9
names: Similarity
messages: Belongs to the IL-17 family.

30608:LOC105861313
gene id: 30608:LOC105861313
uniprot id: A0A8B7F2N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:TAF13
gene id: 30608:TAF13
uniprot id: A0A8B7ECS4
names: Subcellular Location Annotation
messages: Nucleus

30608:AU129 gp01
gene id: 30608:AU129_gp01
uniprot id: D6N8A1
uniprot id: Q9G0S9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme b groups non-covalently.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The cytochrome bc1 complex contains 11 subunits: 3 respiratory subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and UQCRC2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of UQCRFS1). This cytochrome bc1 complex then forms a dimer.
messages: The full-length protein contains only eight transmembrane helices, not nine as predicted by bioinformatics tools.

30608:MED11
gene id: 30608:MED11
uniprot id: A0A8B7HDA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

30608:QSOX2
gene id: 30608:QSOX2
uniprot id: A0A8B7XBM2
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

30608:RAX2
gene id: 30608:RAX2
uniprot id: A0A8B7GPB3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CRX.
messages: May be involved in modulating the expression of photoreceptor specific genes. Binds to the Ret-1 and Bat-1 element within the rhodopsin promoter.
messages: Nucleus

30608:ZBED1
gene id: 30608:ZBED1
uniprot id: A0A8B7GAK3
names: Subcellular Location Annotation
messages: Nucleus

30608:GTF2A1
gene id: 30608:GTF2A1
uniprot id: A0A8B7FXG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

30608:RAB27A
gene id: 30608:RAB27A
uniprot id: A0A8B7HLT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

30608:LOC105874070
gene id: 30608:LOC105874070
uniprot id: A0A8B7GPX1
names: Similarity
messages: Belongs to the CD225/Dispanin family.

30608:LOC105862430
gene id: 30608:LOC105862430
uniprot id: A0A8B7F8C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105858713
gene id: 30608:LOC105858713
uniprot id: A0A8B7ET20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:IPPK
gene id: 30608:IPPK
uniprot id: A0A8C5XM03
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 2 family.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

30608:POU3F3
gene id: 30608:POU3F3
uniprot id: A0A8C5VGB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

30608:RPL18A
gene id: 30608:RPL18A
uniprot id: A0A8B7ECZ5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

30608:DEFB118
gene id: 30608:DEFB118
uniprot id: A0A8B7FN41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

30608:MBTPS1
gene id: 30608:MBTPS1
uniprot id: A0A8B7EH81
uniprot id: A0A8B7EJP0
names: Similarity
messages: Belongs to the peptidase S8 family.

30608:NUDT5
gene id: 30608:NUDT5
uniprot id: A0A8B7GF39
uniprot id: A0A8B7WWK3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

30608:LOC105862411
gene id: 30608:LOC105862411
uniprot id: A0A8B7X0T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spectrin family.
messages: cell cortex
messages: cytoskeleton

30608:RPS9
gene id: 30608:RPS9
uniprot id: A0A8B7GSI6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs.

30608:LOC105875309
gene id: 30608:LOC105875309
uniprot id: A0A8B7GW09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:MECP2
gene id: 30608:MECP2
uniprot id: A0A8C5VU15
names: Function
names: Subcellular Location Annotation
messages: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
messages: Nucleus

30608:BTAF1
gene id: 30608:BTAF1
uniprot id: A0A8B7GEX3
uniprot id: A0A8B7GFP8
names: Subcellular Location Annotation
messages: Nucleus

30608:NAGLU
gene id: 30608:NAGLU
uniprot id: A0A8B7EVW2
names: Subcellular Location Annotation
messages: Lysosome

30608:LOC105858357
gene id: 30608:LOC105858357
uniprot id: A0A8B7EPL9
uniprot id: A0A8B7ERM6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

30608:LOC105861281
gene id: 30608:LOC105861281
uniprot id: A0A8B7F441
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:GPR50
gene id: 30608:GPR50
uniprot id: A0A8B7EB17
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:LOC105862116
gene id: 30608:LOC105862116
uniprot id: A0A8B7F705
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:EVX2
gene id: 30608:EVX2
uniprot id: A0A8B7FJY5
uniprot id: A0A8B7X873
uniprot id: A0A8C5VXY6
names: Subcellular Location Annotation
messages: Nucleus

30608:XDH
gene id: 30608:XDH
uniprot id: A0A8B7HZW4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Homodimer. Interacts with BTN1A1.
messages: Peroxisome

30608:VCL
gene id: 30608:VCL
uniprot id: A0A8B7G0D4
uniprot id: A0A8B7G184
uniprot id: A0A8B7G1M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

30608:MTG2
gene id: 30608:MTG2
uniprot id: A0A8C5W8G6
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

30608:PLSCR3
gene id: 30608:PLSCR3
uniprot id: A0A8B7H6G2
uniprot id: A0A8B7H6G9
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

30608:CA5B
gene id: 30608:CA5B
uniprot id: A0A8B7HQT1
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

30608:LOC105885147
gene id: 30608:LOC105885147
uniprot id: A0A8B7I6G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105865656
gene id: 30608:LOC105865656
uniprot id: A0A8B7FM79
names: Subcellular Location Annotation
messages: Membrane

30608:RPL11
gene id: 30608:RPL11
uniprot id: A0A8B7FCQ6
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

30608:MEIG1
gene id: 30608:MEIG1
uniprot id: A0A8C5VDR7
names: Function
names: Similarity
messages: Belongs to the MEIG1 family.
messages: Essential for spermiogenesis.

30608:LOC109730991
gene id: 30608:LOC109730991
uniprot id: A0A8B7X790
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

30608:F7
gene id: 30608:F7
uniprot id: A0A8B7XFR7
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Heterodimer of a light chain and a heavy chain linked by a disulfide bond.
messages: Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:PRDX6
gene id: 30608:PRDX6
uniprot id: A0A8C5US09
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

30608:SEM1
gene id: 30608:SEM1
uniprot id: A0A8C5VJG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DSS1/SEM1 family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Nucleus

30608:C20H16orf87
gene id: 30608:C20H16orf87
uniprot id: A0A8B7WSH0
names: Similarity
messages: Belongs to the UPF0547 family.

30608:FRAT2
gene id: 30608:FRAT2
uniprot id: A0A8B7GKD0
names: Similarity
messages: Belongs to the GSK-3-binding protein family.

30608:LOC105882517
gene id: 30608:LOC105882517
uniprot id: A0A8B7HRE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

30608:LOC105856653
gene id: 30608:LOC105856653
uniprot id: A0A8B7EI84
names: Subcellular Location Annotation
messages: Nucleus

30608:GRM7
gene id: 30608:GRM7
uniprot id: A0A8B7G399
uniprot id: A0A8B7G3A4
uniprot id: A0A8B7G3A5
uniprot id: A0A8B7G3A6
uniprot id: A0A8B7G455
uniprot id: A0A8B7WWN5
uniprot id: A0A8B7WWZ8
uniprot id: A0A8B7WXF1
uniprot id: A0A8B7WYE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

30608:LOC105866560
gene id: 30608:LOC105866560
uniprot id: A0A8B7FS32
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

30608:ANXA6
gene id: 30608:ANXA6
uniprot id: A0A8C5UIR9
uniprot id: A0A8C5XNG2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome

30608:ADGRF1
gene id: 30608:ADGRF1
uniprot id: A0A8B7X4C8
uniprot id: A0A8C6EFW1
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105884227
gene id: 30608:LOC105884227
uniprot id: A0A8B7XAG8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

30608:CDKN2AIP
gene id: 30608:CDKN2AIP
uniprot id: A0A8B7WKP9
uniprot id: A0A8B7WLD8
uniprot id: A0A8C5Y5V2
names: Similarity
messages: Belongs to the CARF family.

30608:LOC105856105
gene id: 30608:LOC105856105
uniprot id: A0A8B7EEY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

30608:NOBOX
gene id: 30608:NOBOX
uniprot id: A0A8B7GKY2
names: Subcellular Location Annotation
messages: Nucleus

30608:CHST10
gene id: 30608:CHST10
uniprot id: A0A8B7F676
uniprot id: A0A8C5YES9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:SLC16A2
gene id: 30608:SLC16A2
uniprot id: A0A8B7WZ38
names: Subcellular Location Annotation
messages: Membrane

30608:BABAM1
gene id: 30608:BABAM1
uniprot id: A0A8B7WZ58
uniprot id: A0A8C5VNV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BABAM1 family.
messages: Nucleus

30608:TXNL4A
gene id: 30608:TXNL4A
uniprot id: A0A8B7I169
uniprot id: A0A8B7I420
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

30608:NOTCH4
gene id: 30608:NOTCH4
uniprot id: A0A8B7ENK7
uniprot id: A0A8B7ENR5
uniprot id: A0A8B7EQ49
uniprot id: A0A8B7EQR2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

30608:ACTB
gene id: 30608:ACTB
uniprot id: A0A8B7FY80
names: Similarity
messages: Belongs to the actin family.

30608:PATZ1
gene id: 30608:PATZ1
uniprot id: A0A8B7GAI9
uniprot id: A0A8B7GAS5
uniprot id: A0A8B7GB91
uniprot id: A0A8C5Y954
names: Subcellular Location Annotation
messages: Nucleus

30608:TYRP1
gene id: 30608:TYRP1
uniprot id: A0A8C5XF41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

30608:HCRTR2
gene id: 30608:HCRTR2
uniprot id: A0A8C5XT20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:NUP210
gene id: 30608:NUP210
uniprot id: A0A8B7FHD1
uniprot id: A0A8B7FHG3
uniprot id: A0A8B7FHL1
uniprot id: A0A8B7FIP0
uniprot id: A0A8B7WWP6
names: Similarity
messages: Belongs to the NUP210 family.

30608:ARSE
gene id: 30608:ARSE
uniprot id: A0A8B7WYS6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

30608:FAM83G
gene id: 30608:FAM83G
uniprot id: A0A8B7F6K6
names: Similarity
messages: Belongs to the FAM83 family.

30608:API5
gene id: 30608:API5
uniprot id: A0A8B7I5L1
uniprot id: A0A8B7I5M2
uniprot id: A0A8C5VWP2
names: Similarity
messages: Belongs to the API5 family.

30608:F2RL3
gene id: 30608:F2RL3
uniprot id: A0A8B7FWY0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

30608:TFB1M
gene id: 30608:TFB1M
uniprot id: A0A8B7FZS0
uniprot id: A0A8B7G0K6
uniprot id: A0A8B7G0Y2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Interacts with mitochondrial RNA polymerase POLRMT. Interacts with TFAM.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity.

30608:HEPHL1
gene id: 30608:HEPHL1
uniprot id: A0A8C5XCA3
names: Similarity
messages: Belongs to the multicopper oxidase family.

30608:TMTC2
gene id: 30608:TMTC2
uniprot id: A0A8B7FA64
uniprot id: A0A8B7FA65
uniprot id: A0A8C5UTI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

30608:CREBL2
gene id: 30608:CREBL2
uniprot id: A0A8B7H1A6
uniprot id: A0A8B7H1B4
uniprot id: A0A8B7H1G9
uniprot id: A0A8B7H3C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

30608:LOC105859573
gene id: 30608:LOC105859573
uniprot id: A0A8B7EWG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:PNPLA6
gene id: 30608:PNPLA6
uniprot id: A0A8B7I5L3
uniprot id: A0A8B7I5L4
uniprot id: A0A8B7I7L8
uniprot id: A0A8B7I8T4
uniprot id: A0A8B7I8T9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:STS
gene id: 30608:STS
uniprot id: A0A8B7HKC6
uniprot id: A0A8B7HLJ7
uniprot id: A0A8C5Y6Z1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

30608:ORAI3
gene id: 30608:ORAI3
uniprot id: A0A8C5VVF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

30608:LOC105876884
gene id: 30608:LOC105876884
uniprot id: A0A8C5YDP3
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

30608:LOC105876243
gene id: 30608:LOC105876243
uniprot id: A0A8B7GZZ3
uniprot id: A0A8B7WXS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

30608:SLC5A9
gene id: 30608:SLC5A9
uniprot id: A0A8B7H594
uniprot id: A0A8B7H597
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

30608:COG7
gene id: 30608:COG7
uniprot id: A0A8B7HFK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG7 family.
messages: Golgi apparatus membrane
messages: Membrane

30608:ALDH16A1
gene id: 30608:ALDH16A1
uniprot id: A0A8C5VTN2
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Interacts with SPG21.

30608:LOC105855677
gene id: 30608:LOC105855677
uniprot id: A0A8B7ECW1
uniprot id: A0A8B7ECW4
uniprot id: A0A8B7EDE2
uniprot id: A0A8B7EDE7
uniprot id: A0A8B7EFI7
uniprot id: A0A8B7EFJ2
uniprot id: A0A8B7XDC3
names: Similarity
messages: Belongs to the paralemmin family.

30608:AHCYL1
gene id: 30608:AHCYL1
uniprot id: A0A8B7FFC2
uniprot id: A0A8B7FFJ4
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

30608:KATNA1
gene id: 30608:KATNA1
uniprot id: A0A8B7FZW9
uniprot id: A0A8B7G0T3
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit. Interacts with ASPM; the katanin complex formation KATNA1:KATNB1 is required for the association of ASPM. Interacts with dynein and NDEL1. Associates with the E3 ligase complex containing DYRK2, EDD/UBR5, DDB1 and DCAF1 proteins (EDVP complex). Interacts with KLHL42 (via the kelch domains). Interacts with CUL3; the interaction is enhanced by KLHL42. Interacts with KATNB1 and KATNBL1. Interacts with CAMSAP2 and CAMSAP3; leading to regulate the length of CAMSAP-decorated microtubule stretches.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Midbody
messages: Phosphorylation by DYRK2 triggers ubiquitination and subsequent degradation.
messages: The N-terminus is sufficient for interaction with microtubules, although high affinity binding to microtubules also requires an intact C-terminal domain and ATP, which promotes oligomerization.
messages: Ubiquitinated by the BCR(KLHL42) E3 ubiquitin ligase complex, leading to its proteasomal degradation. Ubiquitinated by the EDVP E3 ligase complex and subsequently targeted for proteasomal degradation.
messages: centrosome
messages: spindle
messages: spindle pole

30608:LOC105881939
gene id: 30608:LOC105881939
uniprot id: A0A8B7HR78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:EFNB1
gene id: 30608:EFNB1
uniprot id: A0A8B7EBP3
uniprot id: A0A8B7EC98
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:ITGAV
gene id: 30608:ITGAV
uniprot id: A0A8B7HDD1
uniprot id: A0A8C5W784
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

30608:AIG1
gene id: 30608:AIG1
uniprot id: A0A8B7G013
uniprot id: A0A8B7G0V2
uniprot id: A0A8B7G189
uniprot id: A0A8C5XE55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

30608:P2RX1
gene id: 30608:P2RX1
uniprot id: A0A8B7HCZ2
uniprot id: A0A8B7HCZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

30608:TNNT2
gene id: 30608:TNNT2
uniprot id: A0A8B7EX28
uniprot id: A0A8B7EX37
uniprot id: A0A8B7EZ01
uniprot id: A0A8B7WX46
uniprot id: A0A8B7WXG9
uniprot id: A0A8B7WXX5
uniprot id: A0A8B7WYV6
uniprot id: A0A8B7WYV9
uniprot id: A0A8C5W1V0
uniprot id: A0A8C5YA06
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

30608:TMEM87B
gene id: 30608:TMEM87B
uniprot id: A0A8B7ESX4
uniprot id: A0A8B7ESX8
uniprot id: A0A8C5UVC5
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105862438
gene id: 30608:LOC105862438
uniprot id: A0A8B7F8L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SLC1A1
gene id: 30608:SLC1A1
uniprot id: A0A8B7EFW4
uniprot id: A0A8B7EHN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

30608:PPP3CC
gene id: 30608:PPP3CC
uniprot id: A0A8B7EJC0
uniprot id: A0A8B7EJC7
uniprot id: A0A8B7EJN9
uniprot id: A0A8B7ELP7
uniprot id: A0A8B7ELQ2
uniprot id: A0A8C5UQR0
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

30608:MED21
gene id: 30608:MED21
uniprot id: A0A8C5XLW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

30608:FGB
gene id: 30608:FGB
uniprot id: A0A8C5VJN6
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

30608:LOC105879166
gene id: 30608:LOC105879166
uniprot id: A0A8B7HCR3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:ERP29
gene id: 30608:ERP29
uniprot id: A0A8B7HDI6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Does not seem to be a disulfide isomerase.
messages: Endoplasmic reticulum lumen
messages: Homodimer.
messages: Melanosome

30608:LOC105864631
gene id: 30608:LOC105864631
uniprot id: A0A8B7FHR8
uniprot id: A0A8B7FHS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:HSPB6
gene id: 30608:HSPB6
uniprot id: A0A8B7H2M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Nucleus

30608:PLPPR3
gene id: 30608:PLPPR3
uniprot id: A0A8B7WXD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

30608:PTGDS
gene id: 30608:PTGDS
uniprot id: A0A8C5VIX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Membrane
messages: Monomer.
messages: Nucleus membrane
messages: Rough endoplasmic reticulum
messages: perinuclear region

30608:DISP3
gene id: 30608:DISP3
uniprot id: A0A8C5V0M0
names: Subcellular Location Annotation
messages: Membrane

30608:F12
gene id: 30608:F12
uniprot id: A0A8C5XW84
uniprot id: A0A8C5YC64
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

30608:LOC105874714
gene id: 30608:LOC105874714
uniprot id: A0A8B7WUZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

30608:AKR1A1
gene id: 30608:AKR1A1
uniprot id: A0A8B7H4Z4
uniprot id: A0A8B7H4Z7
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

30608:LOC105868860
gene id: 30608:LOC105868860
uniprot id: A0A8B7G1Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Membrane
messages: Mitochondrion inner membrane

30608:GJB4
gene id: 30608:GJB4
uniprot id: A0A8B7GDM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

30608:ELF3
gene id: 30608:ELF3
uniprot id: A0A8B7EX04
uniprot id: A0A8C5Y9E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

30608:HTR7
gene id: 30608:HTR7
uniprot id: A0A8B7GE78
uniprot id: A0A8B7GE84
uniprot id: A0A8B7GF07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:DCAF11
gene id: 30608:DCAF11
uniprot id: A0A8B7FR22
uniprot id: A0A8B7FS56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat LEC14B family.
messages: Interacts with DDB1 and CUL4A.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

30608:SFN
gene id: 30608:SFN
uniprot id: A0A8C5V5P3
names: Similarity
messages: Belongs to the 14-3-3 family.

30608:GON4L
gene id: 30608:GON4L
uniprot id: A0A8B7GJZ3
uniprot id: A0A8B7GJZ6
uniprot id: A0A8B7GKA3
uniprot id: A0A8B7GKK9
uniprot id: A0A8B7GL49
uniprot id: A0A8B7WZ70
uniprot id: A0A8B7X0Y3
names: Subcellular Location Annotation
messages: Nucleus

30608:LIPT2
gene id: 30608:LIPT2
uniprot id: A0A8C5Y9H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Mitochondrion

30608:NKX2-8
gene id: 30608:NKX2-8
uniprot id: A0A8B7GJ29
names: Subcellular Location Annotation
messages: Nucleus

30608:ATF1
gene id: 30608:ATF1
uniprot id: A0A8B7G5V6
uniprot id: A0A8B7G5Y1
uniprot id: A0A8B7G5Y5
uniprot id: A0A8B7G6P8
uniprot id: A0A8B7G6Q3
names: Subcellular Location Annotation
messages: Nucleus

30608:GSK3B
gene id: 30608:GSK3B
uniprot id: A0A8B7HG11
uniprot id: A0A8B7HG39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
messages: Cytoplasm
messages: Nucleus

30608:SLC13A4
gene id: 30608:SLC13A4
uniprot id: A0A8B7EXT7
uniprot id: A0A8B7EZW0
uniprot id: A0A8B7XBW8
uniprot id: A0A8B7XDM6
uniprot id: A0A8C5Y390
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

30608:ASPN
gene id: 30608:ASPN
uniprot id: A0A8C5Y487
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: extracellular matrix

30608:ARHGEF9
gene id: 30608:ARHGEF9
uniprot id: A0A8B7EIT1
uniprot id: A0A8B7EJ66
uniprot id: A0A8B7EJ67
uniprot id: A0A8B7EL72
uniprot id: A0A8B7WYC9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.
messages: Cytoplasm
messages: Interacts with GPHN.
messages: Postsynaptic density

30608:LOC105862828
gene id: 30608:LOC105862828
uniprot id: A0A8C5XS75
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

30608:LOC105865758
gene id: 30608:LOC105865758
uniprot id: A0A8B7FP01
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

30608:PEPD
gene id: 30608:PEPD
uniprot id: A0A8B7H2Z3
names: Similarity
messages: Belongs to the peptidase M24B family.

30608:USP32
gene id: 30608:USP32
uniprot id: A0A8B7H810
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:SLC25A14
gene id: 30608:SLC25A14
uniprot id: A0A8B7FCG0
uniprot id: A0A8B7FCG9
uniprot id: A0A8B7FCN2
uniprot id: A0A8B7FD81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

30608:IL16
gene id: 30608:IL16
uniprot id: A0A8B7FG58
uniprot id: A0A8B7FG63
uniprot id: A0A8B7FG87
uniprot id: A0A8B7FGB4
uniprot id: A0A8B7FHA1
uniprot id: A0A8B7XA74
uniprot id: A0A8B7XA75
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homotetramer.
messages: Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.
messages: Nucleus
messages: Secreted

30608:DMRTA1
gene id: 30608:DMRTA1
uniprot id: A0A8B7GQ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

30608:LOC105884694
gene id: 30608:LOC105884694
uniprot id: A0A8B7I127
names: Similarity
messages: Belongs to the PWWP3A family.

30608:S100A10
gene id: 30608:S100A10
uniprot id: A0A8B7WVY1
names: Function
messages: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.

30608:NPBWR2
gene id: 30608:NPBWR2
uniprot id: A0A8B7WQC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:SULF2
gene id: 30608:SULF2
uniprot id: A0A8B7ETC6
uniprot id: A0A8C5UZI3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin.
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

30608:NXPH2
gene id: 30608:NXPH2
uniprot id: A0A8B7ELI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

30608:KANSL2
gene id: 30608:KANSL2
uniprot id: A0A8B7FUP3
uniprot id: A0A8C5XC08
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
messages: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.
messages: Nucleus

30608:LOC105875455
gene id: 30608:LOC105875455
uniprot id: A0A8B7GWR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

30608:CFD
gene id: 30608:CFD
uniprot id: A0A8C5VQT3
names: Function
messages: Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.

30608:DSC3
gene id: 30608:DSC3
uniprot id: A0A8B7WR42
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

30608:SYT17
gene id: 30608:SYT17
uniprot id: A0A8B7EB18
uniprot id: A0A8B7EB45
uniprot id: A0A8B7WPA2
uniprot id: A0A8C5VTA5
uniprot id: A0A8C5W429
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Membrane

30608:ODF2
gene id: 30608:ODF2
uniprot id: A0A8B7GVN5
uniprot id: A0A8B7GVP3
uniprot id: A0A8B7GVP5
uniprot id: A0A8B7GVP6
uniprot id: A0A8B7GVQ5
uniprot id: A0A8B7GVQ7
uniprot id: A0A8B7GVR2
uniprot id: A0A8B7GVR4
uniprot id: A0A8B7GVR6
uniprot id: A0A8B7GVU0
uniprot id: A0A8B7GVW1
uniprot id: A0A8B7GVW6
uniprot id: A0A8B7GXG5
uniprot id: A0A8B7GXH0
uniprot id: A0A8B7GXH5
uniprot id: A0A8B7GXI5
uniprot id: A0A8B7GXJ1
uniprot id: A0A8B7GXJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

30608:LOC105884163
gene id: 30608:LOC105884163
uniprot id: A0A8B7HYL0
names: Subcellular Location Annotation
messages: Membrane

30608:MAP3K13
gene id: 30608:MAP3K13
uniprot id: A0A8B7X3S3
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

30608:MED29
gene id: 30608:MED29
uniprot id: A0A8B7H1R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 29 family.
messages: Nucleus

30608:AHSA1
gene id: 30608:AHSA1
uniprot id: A0A8B7EVJ1
uniprot id: A0A8B7X183
names: Similarity
messages: Belongs to the AHA1 family.

30608:NCK1
gene id: 30608:NCK1
uniprot id: A0A8B7X495
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

30608:IL6
gene id: 30608:IL6
uniprot id: A0A8B7GYM7
names: Similarity
messages: Belongs to the IL-6 superfamily.

30608:CXCL13
gene id: 30608:CXCL13
uniprot id: A0A8B7F1A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

30608:ATP2C2
gene id: 30608:ATP2C2
uniprot id: A0A8B7WT08
names: Subcellular Location Annotation
messages: Membrane

30608:SGCZ
gene id: 30608:SGCZ
uniprot id: A0A8B7EKW7
uniprot id: A0A8B7WSQ5
uniprot id: A0A8B7WSQ7
uniprot id: A0A8B7WSU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

30608:S100Z
gene id: 30608:S100Z
uniprot id: A0A8C5V866
names: Similarity
messages: Belongs to the S-100 family.

30608:DLC1
gene id: 30608:DLC1
uniprot id: A0A8B7EKJ2
uniprot id: A0A8B7EKK1
uniprot id: A0A8B7ELV1
uniprot id: A0A8B7EMV5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.
messages: Interacts with EF1A1, facilitates EF1A1 distribution to the membrane periphery and ruffles upon growth factor stimulation and suppresses cell migration.
messages: Membrane
messages: focal adhesion

30608:MMP19
gene id: 30608:MMP19
uniprot id: A0A8B7FIX6
uniprot id: A0A8B7FIY6
uniprot id: A0A8B7FK79
uniprot id: A0A8B7FK84
names: Similarity
messages: Belongs to the peptidase M10A family.

30608:LOC105854868
gene id: 30608:LOC105854868
uniprot id: A0A8B7E9V9
names: Caution
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK. The mature dimeric form interacts with PPP1R16B (via its fourth ankyrin repeat). Interacts with PPP1CA only in the presence of PPP1R16B.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

30608:LOC105858380
gene id: 30608:LOC105858380
uniprot id: A0A8C5V7I8
uniprot id: D1GEY5
names: Subcellular Location Annotation
messages: Membrane

30608:TUT1
gene id: 30608:TUT1
uniprot id: A0A8B7HAF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Nucleus speckle
messages: nucleolus

30608:TRIM2
gene id: 30608:TRIM2
uniprot id: A0A8B7HN33
uniprot id: A0A8B7HN39
uniprot id: A0A8B7HPM6
uniprot id: A0A8B7HQK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

30608:NKX6-2
gene id: 30608:NKX6-2
uniprot id: A0A8B7FR16
names: Subcellular Location Annotation
messages: Nucleus

30608:FFAR1
gene id: 30608:FFAR1
uniprot id: A0A8B7H2Q3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:LIPF
gene id: 30608:LIPF
uniprot id: A0A8C5V221
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

30608:LOC105870822
gene id: 30608:LOC105870822
uniprot id: A0A8B7WXD1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

30608:HOXB2
gene id: 30608:HOXB2
uniprot id: A0A8C5WB65
names: Subcellular Location Annotation
messages: Nucleus

30608:RPL7L1
gene id: 30608:RPL7L1
uniprot id: A0A8B7GYA0
uniprot id: A0A8B7GYC0
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

30608:LOC105884119
gene id: 30608:LOC105884119
uniprot id: A0A8B7HYH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

30608:LOC105884508
gene id: 30608:LOC105884508
uniprot id: A0A8B7I045
names: Similarity
messages: Belongs to the cytochrome P450 family.

30608:C2H1orf43
gene id: 30608:C2H1orf43
uniprot id: A0A8C5W0S4
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion

30608:CS
gene id: 30608:CS
uniprot id: A0A8C5VMK6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the citrate synthase family.
messages: Homodimer.
messages: Mitochondrion matrix

30608:SMARCAL1
gene id: 30608:SMARCAL1
uniprot id: A0A8B7HTT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
messages: Nucleus

30608:OTULIN
gene id: 30608:OTULIN
uniprot id: A0A8B7I4G5
uniprot id: A0A8B7I4G8
uniprot id: A0A8B7I6H0
uniprot id: A0A8B7I7I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

30608:ATG4A
gene id: 30608:ATG4A
uniprot id: A0A8B7FCW3
uniprot id: A0A8C5XJY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

30608:LOC105867131
gene id: 30608:LOC105867131
uniprot id: A0A8B7WN03
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:LOC109730695
gene id: 30608:LOC109730695
uniprot id: A0A8B7X3T9
names: Subcellular Location Annotation
messages: Membrane

30608:PER2
gene id: 30608:PER2
uniprot id: A0A8B7FQI6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

30608:DCP2
gene id: 30608:DCP2
uniprot id: A0A8B7GAQ9
uniprot id: A0A8C5XWD8
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

30608:PDK2
gene id: 30608:PDK2
uniprot id: A0A8B7I355
uniprot id: A0A8B7I563
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

30608:GPIHBP1
gene id: 30608:GPIHBP1
uniprot id: A0A8B7FIG7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

30608:OPA3
gene id: 30608:OPA3
uniprot id: A0A8B7G4U6
uniprot id: A0A8C6EJ02
names: Function
names: Similarity
messages: Belongs to the OPA3 family.
messages: May play some role in mitochondrial processes.

30608:MASP2
gene id: 30608:MASP2
uniprot id: A0A8B7I780
uniprot id: A0A8B7I7D6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

30608:GRB7
gene id: 30608:GRB7
uniprot id: A0A8B7GFY1
uniprot id: A0A8C5WBP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

30608:ACTR3B
gene id: 30608:ACTR3B
uniprot id: A0A8B7HUE3
uniprot id: A0A8B7HUF2
uniprot id: A0A8B7HUF8
uniprot id: A0A8B7HWJ4
uniprot id: A0A8B7HWM2
names: Similarity
messages: Belongs to the actin family.

30608:ZSCAN9
gene id: 30608:ZSCAN9
uniprot id: A0A8C5Y953
names: Subcellular Location Annotation
messages: Nucleus

30608:LOC105881591
gene id: 30608:LOC105881591
uniprot id: A0A8B7X498
names: Subcellular Location Annotation
messages: Membrane

30608:SLC39A14
gene id: 30608:SLC39A14
uniprot id: A0A8B7EJA8
uniprot id: A0A8B7EJL6
names: Subcellular Location Annotation
messages: Membrane

30608:LOC105866000
gene id: 30608:LOC105866000
uniprot id: A0A8B7FP72
uniprot id: A0A8B7FPG9
uniprot id: A0A8B7FQA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

30608:STIM2
gene id: 30608:STIM2
uniprot id: A0A8B7GXL8
uniprot id: A0A8C5VE14
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

30608:LPAR5
gene id: 30608:LPAR5
uniprot id: A0A8B7G1S2
uniprot id: A0A8B7G1T0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.