298596:BI350 RS10425
gene id: 298596:BI350_RS10425
uniprot id: A0A1D8JGT7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

298596:BI350 RS03975
gene id: 298596:BI350_RS03975
uniprot id: A0A1D8JDN7
names: Similarity
messages: Belongs to the peptidase M29 family.

298596:BI350 RS10610
gene id: 298596:BI350_RS10610
uniprot id: A0A1D8JGX8
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

298596:BI350 RS05110
gene id: 298596:BI350_RS05110
uniprot id: A0A1D8JE79
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

298596:BI350 RS12140
gene id: 298596:BI350_RS12140
uniprot id: A0A1D8JHN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

298596:BI350 RS12830
gene id: 298596:BI350_RS12830
uniprot id: A0A1D8JHY1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

298596:BI350 RS02925
gene id: 298596:BI350_RS02925
uniprot id: A0A1D8JD95
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS03990
gene id: 298596:BI350_RS03990
uniprot id: A0A1D8JDP4
names: Similarity
messages: Belongs to the UPF0435 family.

298596:BI350 RS07730
gene id: 298596:BI350_RS07730
uniprot id: A0A1D8JFH9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS10580
gene id: 298596:BI350_RS10580
uniprot id: A0A1D8JGU8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

298596:BI350 RS13100
gene id: 298596:BI350_RS13100
uniprot id: A0A1D8JI45
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

298596:BI350 RS11940
gene id: 298596:BI350_RS11940
uniprot id: A0A1D8JHK9
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS10550
gene id: 298596:BI350_RS10550
uniprot id: A0A1D8JGW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

298596:BI350 RS15750
gene id: 298596:BI350_RS15750
uniprot id: A0A1D8JJI3
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

298596:BI350 RS10530
gene id: 298596:BI350_RS10530
uniprot id: A0A1D8JGU1
names: Similarity
messages: Belongs to the sigma-70 factor family.

298596:BI350 RS13920
gene id: 298596:BI350_RS13920
uniprot id: A0A1D8JII4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

298596:BI350 RS13590
gene id: 298596:BI350_RS13590
uniprot id: A0A1D8JIG2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

298596:BI350 RS02775
gene id: 298596:BI350_RS02775
uniprot id: A0A1D8JD53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS11600
gene id: 298596:BI350_RS11600
uniprot id: A0A1D8JHF5
names: Similarity
messages: Belongs to the ThiD family.

298596:BI350 RS06955
gene id: 298596:BI350_RS06955
uniprot id: A0A1D8JF24
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

298596:BI350 RS11485
gene id: 298596:BI350_RS11485
uniprot id: A0A1D8JHD0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

298596:BI350 RS12600
gene id: 298596:BI350_RS12600
uniprot id: A0A1D8JKK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

298596:BI350 RS08210
gene id: 298596:BI350_RS08210
uniprot id: A0A1D8JFM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

298596:BI350 RS06615
gene id: 298596:BI350_RS06615
uniprot id: A0A1D8JEV4
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

298596:BI350 RS01345
gene id: 298596:BI350_RS01345
uniprot id: A0A1D8JCF3
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

298596:BI350 RS12865
gene id: 298596:BI350_RS12865
uniprot id: A0A1D8JHZ7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

298596:BI350 RS07795
gene id: 298596:BI350_RS07795
uniprot id: A0A1D8JKE5
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

298596:BI350 RS08895
gene id: 298596:BI350_RS08895
uniprot id: A0A1D8JG06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS15675
gene id: 298596:BI350_RS15675
uniprot id: A0A1D8JJF3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

298596:BI350 RS10080
gene id: 298596:BI350_RS10080
uniprot id: A0A1D8JGM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

298596:BI350 RS00775
gene id: 298596:BI350_RS00775
uniprot id: A0A1D8JC63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

298596:BI350 RS04575
gene id: 298596:BI350_RS04575
uniprot id: A0A1D8JDY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

298596:BI350 RS16285
gene id: 298596:BI350_RS16285
uniprot id: A0A1D8JJS7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

298596:BI350 RS01860
gene id: 298596:BI350_RS01860
uniprot id: A0A1D8JCP1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

298596:BI350 RS10965
gene id: 298596:BI350_RS10965
uniprot id: A0A1D8JH14
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS15525
gene id: 298596:BI350_RS15525
uniprot id: A0A1D8JJD3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

298596:BI350 RS05785
gene id: 298596:BI350_RS05785
uniprot id: A0A1D8JK90
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS06545
gene id: 298596:BI350_RS06545
uniprot id: A0A1D8JEU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

298596:BI350 RS08690
gene id: 298596:BI350_RS08690
uniprot id: A0A1D8JFY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

298596:BI350 RS03705
gene id: 298596:BI350_RS03705
uniprot id: A0A1D8JDK0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

298596:BI350 RS14310
gene id: 298596:BI350_RS14310
uniprot id: A0A1D8JIR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS08715
gene id: 298596:BI350_RS08715
uniprot id: A0A1D8JG07
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

298596:BI350 RS01160
gene id: 298596:BI350_RS01160
uniprot id: A0A1D8JCC0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

298596:BI350 RS02100
gene id: 298596:BI350_RS02100
uniprot id: A0A1D8JCS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

298596:BI350 RS02410
gene id: 298596:BI350_RS02410
uniprot id: A0A1D8JCY9
names: Similarity
messages: Belongs to the EamA transporter family.

298596:BI350 RS05380
gene id: 298596:BI350_RS05380
uniprot id: A0A1D8JEC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

298596:BI350 RS05115
gene id: 298596:BI350_RS05115
uniprot id: A0A1D8JE80
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

298596:BI350 RS13985
gene id: 298596:BI350_RS13985
uniprot id: A0A1D8JIM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.

298596:BI350 RS12085
gene id: 298596:BI350_RS12085
uniprot id: A0A1D8JHM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

298596:BI350 RS10505
gene id: 298596:BI350_RS10505
uniprot id: A0A1D8JGT5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

298596:BI350 RS14065
gene id: 298596:BI350_RS14065
uniprot id: A0A1D8JIL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

298596:BI350 RS06775
gene id: 298596:BI350_RS06775
uniprot id: A0A1D8JEY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

298596:BI350 RS06845
gene id: 298596:BI350_RS06845
uniprot id: A0A1D8JEZ7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

298596:BI350 RS03245
gene id: 298596:BI350_RS03245
uniprot id: A0A1D8JDB1
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

298596:BI350 RS03045
gene id: 298596:BI350_RS03045
uniprot id: A0A1D8JK56
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

298596:BI350 RS06205
gene id: 298596:BI350_RS06205
uniprot id: A0A1D8JEP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

298596:BI350 RS06145
gene id: 298596:BI350_RS06145
uniprot id: A0A1D8JEN4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS04630
gene id: 298596:BI350_RS04630
uniprot id: A0A1D8JDY0
names: Similarity
messages: Belongs to the EamA transporter family.

298596:BI350 RS15875
gene id: 298596:BI350_RS15875
uniprot id: A0A1D8JJL5
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the octanoyltransferase LipL family.
messages: Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.
messages: The reaction proceeds via a thioester-linked acyl-enzyme intermediate.

298596:BI350 RS06210
gene id: 298596:BI350_RS06210
uniprot id: A0A1D8JEM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

298596:BI350 RS06600
gene id: 298596:BI350_RS06600
uniprot id: A0A1D8JEV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

298596:BI350 RS06785
gene id: 298596:BI350_RS06785
uniprot id: A0A1D8JEY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

298596:BI350 RS08700
gene id: 298596:BI350_RS08700
uniprot id: A0A1D8JFY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

298596:BI350 RS14030
gene id: 298596:BI350_RS14030
uniprot id: A0A1D8JIJ8
names: Similarity
messages: Belongs to the IMPACT family.

298596:BI350 RS01195
gene id: 298596:BI350_RS01195
uniprot id: A0A1D8JCC7
names: Similarity
messages: Belongs to the ParB family.

298596:BI350 RS06170
gene id: 298596:BI350_RS06170
uniprot id: A0A1D8JEL7
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS07255
gene id: 298596:BI350_RS07255
uniprot id: A0A1D8JF76
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS16420
gene id: 298596:BI350_RS16420
uniprot id: A0A1D8JJU2
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS12535
gene id: 298596:BI350_RS12535
uniprot id: A0A1D8JHV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

298596:BI350 RS06805
gene id: 298596:BI350_RS06805
uniprot id: A0A1D8JF17
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

298596:BI350 RS10260
gene id: 298596:BI350_RS10260
uniprot id: A0A1D8JGM8
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

298596:BI350 RS15565
gene id: 298596:BI350_RS15565
uniprot id: A0A1D8JJE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

298596:BI350 RS12585
gene id: 298596:BI350_RS12585
uniprot id: A0A1D8JHU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

298596:BI350 RS11860
gene id: 298596:BI350_RS11860
uniprot id: A0A1D8JHK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

298596:BI350 RS16105
gene id: 298596:BI350_RS16105
uniprot id: A0A1D8JJQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

298596:BI350 RS12930
gene id: 298596:BI350_RS12930
uniprot id: A0A1D8JI16
names: Similarity
messages: Belongs to the transpeptidase family.

298596:BI350 RS13355
gene id: 298596:BI350_RS13355
uniprot id: A0A1D8JI77
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS12475
gene id: 298596:BI350_RS12475
uniprot id: A0A1D8JHS3
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

298596:BI350 RS12960
gene id: 298596:BI350_RS12960
uniprot id: A0A1D8JI47
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

298596:BI350 RS06440
gene id: 298596:BI350_RS06440
uniprot id: A0A1D8JEU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

298596:BI350 RS13625
gene id: 298596:BI350_RS13625
uniprot id: A0A1D8JID1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0344 family.
messages: Cell membrane

298596:BI350 RS09765
gene id: 298596:BI350_RS09765
uniprot id: A0A1D8JGG6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

298596:BI350 RS06460
gene id: 298596:BI350_RS06460
uniprot id: A0A1D8JES8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

298596:BI350 RS05695
gene id: 298596:BI350_RS05695
uniprot id: A0A1D8JEH3
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS14455
gene id: 298596:BI350_RS14455
uniprot id: A0A1D8JKM4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

298596:BI350 RS05475
gene id: 298596:BI350_RS05475
uniprot id: A0A1D8JEB1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

298596:BI350 RS10250
gene id: 298596:BI350_RS10250
uniprot id: A0A1D8JGN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

298596:BI350 RS13865
gene id: 298596:BI350_RS13865
uniprot id: A0A1D8JIH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

298596:BI350 RS16345
gene id: 298596:BI350_RS16345
uniprot id: A0A1D8JJT4
names: Cofactor
names: Function
names: PTM
names: Subcellular Location Annotation
messages: Autophosphorylated.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

298596:BI350 RS14620
gene id: 298596:BI350_RS14620
uniprot id: A0A1D8JIW9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

298596:BI350 RS12920
gene id: 298596:BI350_RS12920
uniprot id: A0A1D8JI27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

298596:BI350 RS08770
gene id: 298596:BI350_RS08770
uniprot id: A0A1D8JFX9
names: Similarity
messages: Belongs to the UPF0735 family.

298596:BI350 RS16185
gene id: 298596:BI350_RS16185
uniprot id: A0A1D8JJP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS16220
gene id: 298596:BI350_RS16220
uniprot id: A0A1D8JJS1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

298596:BI350 RS11520
gene id: 298596:BI350_RS11520
uniprot id: A0A1D8JHE7
names: Similarity
messages: Belongs to the GerABKA family.

298596:BI350 RS12040
gene id: 298596:BI350_RS12040
uniprot id: A0A1D8JHJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS09400
gene id: 298596:BI350_RS09400
uniprot id: A0A1D8JG73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS05805
gene id: 298596:BI350_RS05805
uniprot id: A0A1D8JEG1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

298596:BI350 RS02500
gene id: 298596:BI350_RS02500
uniprot id: A0A1D8JK07
names: Similarity
messages: Belongs to the WrbA family.

298596:BI350 RS15805
gene id: 298596:BI350_RS15805
uniprot id: A0A1D8JJJ1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

298596:BI350 RS15670
gene id: 298596:BI350_RS15670
uniprot id: A0A1D8JJF8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

298596:BI350 RS05875
gene id: 298596:BI350_RS05875
uniprot id: A0A1D8JEI6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

298596:BI350 RS12735
gene id: 298596:BI350_RS12735
uniprot id: A0A1D8JHX5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

298596:BI350 RS14830
gene id: 298596:BI350_RS14830
uniprot id: A0A1D8JJ02
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

298596:BI350 RS06275
gene id: 298596:BI350_RS06275
uniprot id: A0A1D8JEN9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS14110
gene id: 298596:BI350_RS14110
uniprot id: A0A1D8JIN6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

298596:BI350 RS12635
gene id: 298596:BI350_RS12635
uniprot id: A0A1D8JHY9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

298596:BI350 RS06415
gene id: 298596:BI350_RS06415
uniprot id: A0A1D8JES9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

298596:BI350 RS14570
gene id: 298596:BI350_RS14570
uniprot id: A0A1D8JIV9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

298596:BI350 RS01710
gene id: 298596:BI350_RS01710
uniprot id: A0A1D8JCK8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

298596:BI350 RS15730
gene id: 298596:BI350_RS15730
uniprot id: A0A1D8JJG5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS14150
gene id: 298596:BI350_RS14150
uniprot id: A0A1D8JIM5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

298596:BI350 RS15635
gene id: 298596:BI350_RS15635
uniprot id: A0A1D8JJE4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

298596:BI350 RS01935
gene id: 298596:BI350_RS01935
uniprot id: A0A1D8JCP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

298596:BI350 RS12465
gene id: 298596:BI350_RS12465
uniprot id: A0A1D8JHV3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

298596:BI350 RS02235
gene id: 298596:BI350_RS02235
uniprot id: A0A1D8JCW0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

298596:BI350 RS14895
gene id: 298596:BI350_RS14895
uniprot id: A0A1D8JJ36
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

298596:BI350 RS11540
gene id: 298596:BI350_RS11540
uniprot id: A0A1D8JHB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

298596:BI350 RS06925
gene id: 298596:BI350_RS06925
uniprot id: A0A1D8JF21
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

298596:BI350 RS08580
gene id: 298596:BI350_RS08580
uniprot id: A0A1D8JFU2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

298596:BI350 RS07770
gene id: 298596:BI350_RS07770
uniprot id: A0A1D8JFF2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

298596:BI350 RS06445
gene id: 298596:BI350_RS06445
uniprot id: A0A1D8JES2
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

298596:BI350 RS15530
gene id: 298596:BI350_RS15530
uniprot id: A0A1D8JJC8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

298596:BI350 RS05170
gene id: 298596:BI350_RS05170
uniprot id: A0A1D8JE86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

298596:BI350 RS07270
gene id: 298596:BI350_RS07270
uniprot id: A0A1D8JFA0
names: Subcellular Location Annotation
messages: Cytoplasm

298596:BI350 RS04680
gene id: 298596:BI350_RS04680
uniprot id: A0A1D8JDY9
names: Similarity
messages: Belongs to the Dps family.

298596:BI350 RS11200
gene id: 298596:BI350_RS11200
uniprot id: A0A1D8JH62
names: Caution
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS05755
gene id: 298596:BI350_RS05755
uniprot id: A0A1D8JEF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

298596:BI350 RS01190
gene id: 298596:BI350_RS01190
uniprot id: A0A1D8JCC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.

298596:BI350 RS10625
gene id: 298596:BI350_RS10625
uniprot id: A0A1D8JGX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS11830
gene id: 298596:BI350_RS11830
uniprot id: A0A1D8JKI2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

298596:BI350 RS00935
gene id: 298596:BI350_RS00935
uniprot id: A0A1D8JC91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

298596:BI350 RS07260
gene id: 298596:BI350_RS07260
uniprot id: A0A1D8JF65
names: Subcellular Location Annotation
messages: Cytoplasm

298596:BI350 RS00200
gene id: 298596:BI350_RS00200
uniprot id: A0A1D8JBX9
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS12335
gene id: 298596:BI350_RS12335
uniprot id: A0A1D8JHP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

298596:BI350 RS13020
gene id: 298596:BI350_RS13020
uniprot id: A0A1D8JI21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

298596:BI350 RS06410
gene id: 298596:BI350_RS06410
uniprot id: A0A1D8JEU2
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

298596:BI350 RS08915
gene id: 298596:BI350_RS08915
uniprot id: A0A1D8JG11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS04450
gene id: 298596:BI350_RS04450
uniprot id: A0A1D8JDY3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

298596:BI350 RS05880
gene id: 298596:BI350_RS05880
uniprot id: A0A1D8JEH7
names: Similarity
messages: Belongs to the transpeptidase family.

298596:BI350 RS09650
gene id: 298596:BI350_RS09650
uniprot id: A0A1D8JGB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

298596:BI350 RS02385
gene id: 298596:BI350_RS02385
uniprot id: A0A1D8JCY6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

298596:BI350 RS07065
gene id: 298596:BI350_RS07065
uniprot id: A0A1D8JF36
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

298596:BI350 RS06915
gene id: 298596:BI350_RS06915
uniprot id: A0A1D8JF18
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

298596:BI350 RS08105
gene id: 298596:BI350_RS08105
uniprot id: A0A1D8JFK9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS00190
gene id: 298596:BI350_RS00190
uniprot id: A0A1D8JBY0
names: Similarity
messages: Belongs to the CdaR family.

298596:BI350 RS11205
gene id: 298596:BI350_RS11205
uniprot id: A0A1D8JH53
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

298596:BI350 RS08880
gene id: 298596:BI350_RS08880
uniprot id: A0A1D8JG17
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

298596:BI350 RS03220
gene id: 298596:BI350_RS03220
uniprot id: A0A1D8JDC5
names: Similarity
messages: Belongs to the EamA transporter family.

298596:BI350 RS08955
gene id: 298596:BI350_RS08955
uniprot id: A0A1D8JG24
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS12155
gene id: 298596:BI350_RS12155
uniprot id: A0A1D8JKJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

298596:BI350 RS10290
gene id: 298596:BI350_RS10290
uniprot id: A0A1D8JGP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

298596:BI350 RS05160
gene id: 298596:BI350_RS05160
uniprot id: A0A1D8JE89
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

298596:BI350 RS01285
gene id: 298596:BI350_RS01285
uniprot id: A0A1D8JCE3
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS12560
gene id: 298596:BI350_RS12560
uniprot id: A0A1D8JHT3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

298596:BI350 RS04690
gene id: 298596:BI350_RS04690
uniprot id: A0A1D8JE00
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

298596:BI350 RS04885
gene id: 298596:BI350_RS04885
uniprot id: A0A1D8JE44
names: Similarity
messages: Belongs to the manganese catalase family.

298596:BI350 RS03205
gene id: 298596:BI350_RS03205
uniprot id: A0A1D8JDB6
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

298596:BI350 RS06570
gene id: 298596:BI350_RS06570
uniprot id: A0A1D8JEV1
names: Similarity
messages: Belongs to the citrate synthase family.

298596:BI350 RS13330
gene id: 298596:BI350_RS13330
uniprot id: A0A1D8JI82
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS02740
gene id: 298596:BI350_RS02740
uniprot id: A0A1D8JD39
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

298596:BI350 RS13465
gene id: 298596:BI350_RS13465
uniprot id: A0A1D8JIC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

298596:BI350 RS15700
gene id: 298596:BI350_RS15700
uniprot id: A0A1D8JJH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

298596:BI350 RS12310
gene id: 298596:BI350_RS12310
uniprot id: A0A1D8JHP8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

298596:BI350 RS02545
gene id: 298596:BI350_RS02545
uniprot id: A0A1D8JD16
names: Subcellular Location Annotation
messages: Cytoplasm

298596:BI350 RS13520
gene id: 298596:BI350_RS13520
uniprot id: A0A1D8JIB0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

298596:BI350 RS08125
gene id: 298596:BI350_RS08125
uniprot id: A0A1D8JFL5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

298596:BI350 RS04865
gene id: 298596:BI350_RS04865
uniprot id: A0A1D8JE23
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

298596:BI350 RS02180
gene id: 298596:BI350_RS02180
uniprot id: A0A1D8JCU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

298596:BI350 RS14170
gene id: 298596:BI350_RS14170
uniprot id: A0A1D8JIM9
names: Similarity
messages: Belongs to the proline racemase family.

298596:BI350 RS09280
gene id: 298596:BI350_RS09280
uniprot id: A0A1D8JG57
names: Subcellular Location Annotation
messages: Cytoplasm

298596:BI350 RS10940
gene id: 298596:BI350_RS10940
uniprot id: A0A1D8JH02
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

298596:BI350 RS12190
gene id: 298596:BI350_RS12190
uniprot id: A0A1D8JHM7
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS01485
gene id: 298596:BI350_RS01485
uniprot id: A0A1D8JCG8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

298596:BI350 RS16175
gene id: 298596:BI350_RS16175
uniprot id: A0A1D8JJR2
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

298596:BI350 RS12530
gene id: 298596:BI350_RS12530
uniprot id: A0A1D8JHT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

298596:BI350 RS01950
gene id: 298596:BI350_RS01950
uniprot id: A0A1D8JCR2
names: Similarity
messages: Belongs to the CtsR family.

298596:BI350 RS15780
gene id: 298596:BI350_RS15780
uniprot id: A0A1D8JJI7
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

298596:BI350 RS16235
gene id: 298596:BI350_RS16235
uniprot id: A0A1D8JJR0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS10270
gene id: 298596:BI350_RS10270
uniprot id: A0A1D8JGQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

298596:BI350 RS05890
gene id: 298596:BI350_RS05890
uniprot id: A0A1D8JEJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

298596:BI350 RS10280
gene id: 298596:BI350_RS10280
uniprot id: A0A1D8JGR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

298596:BI350 RS13645
gene id: 298596:BI350_RS13645
uniprot id: A0A1D8JIG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

298596:BI350 RS05420
gene id: 298596:BI350_RS05420
uniprot id: A0A1D8JED8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

298596:BI350 RS14615
gene id: 298596:BI350_RS14615
uniprot id: A0A1D8JIV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS00450
gene id: 298596:BI350_RS00450
uniprot id: A0A1D8JC23
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

298596:BI350 RS05010
gene id: 298596:BI350_RS05010
uniprot id: A0A1D8JE81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

298596:BI350 RS00225
gene id: 298596:BI350_RS00225
uniprot id: A0A1D8JBY1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

298596:BI350 RS11410
gene id: 298596:BI350_RS11410
uniprot id: A0A1D8JH91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Involved in the degradation of specific anti-sigma factors.
messages: Membrane

298596:BI350 RS08865
gene id: 298596:BI350_RS08865
uniprot id: A0A1D8JG09
names: Similarity
messages: Belongs to the RecJ family.

298596:BI350 RS01010
gene id: 298596:BI350_RS01010
uniprot id: A0A1D8JCA2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

298596:BI350 RS11440
gene id: 298596:BI350_RS11440
uniprot id: A0A1D8JKG6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

298596:BI350 RS09625
gene id: 298596:BI350_RS09625
uniprot id: A0A1D8JGE9
names: Similarity
messages: Belongs to the HesB/IscA family.

298596:BI350 RS08540
gene id: 298596:BI350_RS08540
uniprot id: A0A1D8JFT9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

298596:BI350 RS00430
gene id: 298596:BI350_RS00430
uniprot id: A0A1D8JC21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

298596:BI350 RS06930
gene id: 298596:BI350_RS06930
uniprot id: A0A1D8JF13
names: Similarity
messages: Belongs to the thioredoxin family.

298596:BI350 RS06885
gene id: 298596:BI350_RS06885
uniprot id: A0A1D8JF05
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS12055
gene id: 298596:BI350_RS12055
uniprot id: A0A1D8JHM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

298596:BI350 RS09265
gene id: 298596:BI350_RS09265
uniprot id: A0A1D8JG68
names: Similarity
messages: Belongs to the TelA family.

298596:BI350 RS07780
gene id: 298596:BI350_RS07780
uniprot id: A0A1D8JFI9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

298596:BI350 RS04540
gene id: 298596:BI350_RS04540
uniprot id: A0A1D8JDW6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

298596:BI350 RS07340
gene id: 298596:BI350_RS07340
uniprot id: A0A1D8JF81
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

298596:BI350 RS04085
gene id: 298596:BI350_RS04085
uniprot id: A0A1D8JDR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS05425
gene id: 298596:BI350_RS05425
uniprot id: A0A1D8JEA0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

298596:BI350 RS04055
gene id: 298596:BI350_RS04055
uniprot id: A0A1D8JDP8
names: Similarity
messages: Belongs to the UPF0374 family.

298596:BI350 RS09215
gene id: 298596:BI350_RS09215
uniprot id: A0A1D8JG72
names: Similarity
messages: Belongs to the peptidase S41A family.

298596:BI350 RS12220
gene id: 298596:BI350_RS12220
uniprot id: A0A1D8JHN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

298596:BI350 RS03180
gene id: 298596:BI350_RS03180
uniprot id: A0A1D8JDC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

298596:BI350 RS00215
gene id: 298596:BI350_RS00215
uniprot id: A0A1D8JBY5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

298596:BI350 RS02050
gene id: 298596:BI350_RS02050
uniprot id: A0A1D8JCR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

298596:BI350 RS13735
gene id: 298596:BI350_RS13735
uniprot id: A0A1D8JIF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

298596:BI350 RS08945
gene id: 298596:BI350_RS08945
uniprot id: A0A1D8JG05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

298596:BI350 RS08570
gene id: 298596:BI350_RS08570
uniprot id: A0A1D8JKC2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

298596:BI350 RS02800
gene id: 298596:BI350_RS02800
uniprot id: A0A1D8JD50
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

298596:BI350 RS08045
gene id: 298596:BI350_RS08045
uniprot id: A0A1D8JFK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

298596:BI350 RS16280
gene id: 298596:BI350_RS16280
uniprot id: A0A1D8JJT6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

298596:BI350 RS01875
gene id: 298596:BI350_RS01875
uniprot id: A0A1D8JCP6
names: Similarity
messages: Belongs to the WrbA family.

298596:BI350 RS16495
gene id: 298596:BI350_RS16495
uniprot id: A0A1D8JJU4
names: Similarity
messages: Belongs to the PspA/IM30 family.

298596:BI350 RS10050
gene id: 298596:BI350_RS10050
uniprot id: A0A1D8JGL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

298596:BI350 RS06480
gene id: 298596:BI350_RS06480
uniprot id: A0A1D8JET2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

298596:BI350 RS00160
gene id: 298596:BI350_RS00160
uniprot id: A0A1D8JBW6
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

298596:BI350 RS08830
gene id: 298596:BI350_RS08830
uniprot id: A0A1D8JG14
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS12795
gene id: 298596:BI350_RS12795
uniprot id: A0A1D8JI12
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS10880
gene id: 298596:BI350_RS10880
uniprot id: A0A1D8JH18
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS05705
gene id: 298596:BI350_RS05705
uniprot id: A0A1D8JK64
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

298596:BI350 RS06875
gene id: 298596:BI350_RS06875
uniprot id: A0A1D8JF03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

298596:BI350 RS16240
gene id: 298596:BI350_RS16240
uniprot id: A0A1D8JJQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

298596:BI350 RS09865
gene id: 298596:BI350_RS09865
uniprot id: A0A1D8JGG9
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box).
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

298596:BI350 RS10025
gene id: 298596:BI350_RS10025
uniprot id: A0A1D8JGK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS15655
gene id: 298596:BI350_RS15655
uniprot id: A0A1D8JJF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

298596:BI350 RS14160
gene id: 298596:BI350_RS14160
uniprot id: A0A1D8JIN9
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS13350
gene id: 298596:BI350_RS13350
uniprot id: A0A1D8JI78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

298596:BI350 RS02160
gene id: 298596:BI350_RS02160
uniprot id: A0A1D8JCU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

298596:BI350 RS13870
gene id: 298596:BI350_RS13870
uniprot id: A0A1D8JII1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

298596:BI350 RS00830
gene id: 298596:BI350_RS00830
uniprot id: A0A1D8JC72
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS12345
gene id: 298596:BI350_RS12345
uniprot id: A0A1D8JHT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

298596:BI350 RS12955
gene id: 298596:BI350_RS12955
uniprot id: A0A1D8JI41
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS04510
gene id: 298596:BI350_RS04510
uniprot id: A0A1D8JDZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

298596:BI350 RS01080
gene id: 298596:BI350_RS01080
uniprot id: A0A1D8JCB1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS05975
gene id: 298596:BI350_RS05975
uniprot id: A0A1D8JEM2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

298596:BI350 RS05895
gene id: 298596:BI350_RS05895
uniprot id: A0A1D8JEI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

298596:BI350 RS07050
gene id: 298596:BI350_RS07050
uniprot id: A0A1D8JF40
names: Similarity
messages: Belongs to the EamA transporter family.

298596:BI350 RS05175
gene id: 298596:BI350_RS05175
uniprot id: A0A1D8JK61
names: Similarity
messages: Belongs to the EamA transporter family.

298596:BI350 RS11220
gene id: 298596:BI350_RS11220
uniprot id: A0A1D8JH78
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS13070
gene id: 298596:BI350_RS13070
uniprot id: A0A1D8JI68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

298596:BI350 RS06130
gene id: 298596:BI350_RS06130
uniprot id: A0A1D8JEM7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS09005
gene id: 298596:BI350_RS09005
uniprot id: A0A1D8JG32
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

298596:BI350 RS12945
gene id: 298596:BI350_RS12945
uniprot id: A0A1D8JI09
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

298596:BI350 RS01970
gene id: 298596:BI350_RS01970
uniprot id: A0A1D8JCR1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

298596:BI350 RS03665
gene id: 298596:BI350_RS03665
uniprot id: A0A1D8JDL0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

298596:BI350 RS04110
gene id: 298596:BI350_RS04110
uniprot id: A0A1D8JDR0
names: Similarity
messages: Belongs to the Fur family.

298596:BI350 RS08815
gene id: 298596:BI350_RS08815
uniprot id: A0A1D8JFZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

298596:BI350 RS04560
gene id: 298596:BI350_RS04560
uniprot id: A0A1D8JDZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

298596:BI350 RS01090
gene id: 298596:BI350_RS01090
uniprot id: A0A1D8JCB0
names: Similarity
messages: Belongs to the PdxS/SNZ family.

298596:BI350 RS14450
gene id: 298596:BI350_RS14450
uniprot id: A0A1D8JIT0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

298596:BI350 RS10480
gene id: 298596:BI350_RS10480
uniprot id: A0A1D8JGU7
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

298596:BI350 RS03810
gene id: 298596:BI350_RS03810
uniprot id: A0A1D8JDK7
names: Similarity
messages: Belongs to the MQO family.

298596:BI350 RS12675
gene id: 298596:BI350_RS12675
uniprot id: A0A1D8JHV5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

298596:BI350 RS06285
gene id: 298596:BI350_RS06285
uniprot id: A0A1D8JEQ6
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS15925
gene id: 298596:BI350_RS15925
uniprot id: A0A1D8JJK9
names: Similarity
messages: Belongs to the ThiD family.

298596:BI350 RS02090
gene id: 298596:BI350_RS02090
uniprot id: A0A1D8JCS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

298596:BI350 RS14280
gene id: 298596:BI350_RS14280
uniprot id: A0A1D8JIR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS04240
gene id: 298596:BI350_RS04240
uniprot id: A0A1D8JDS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS02885
gene id: 298596:BI350_RS02885
uniprot id: A0A1D8JD67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

298596:BI350 RS06580
gene id: 298596:BI350_RS06580
uniprot id: A0A1D8JEV6
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

298596:BI350 RS16075
gene id: 298596:BI350_RS16075
uniprot id: A0A1D8JJM6
names: Similarity
messages: Belongs to the EamA transporter family.

298596:BI350 RS06810
gene id: 298596:BI350_RS06810
uniprot id: A0A1D8JEZ6
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

298596:BI350 RS04265
gene id: 298596:BI350_RS04265
uniprot id: A0A1D8JDS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

298596:BI350 RS01425
gene id: 298596:BI350_RS01425
uniprot id: A0A1D8JCG0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

298596:BI350 RS00885
gene id: 298596:BI350_RS00885
uniprot id: A0A1D8JC83
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

298596:BI350 RS10945
gene id: 298596:BI350_RS10945
uniprot id: A0A1D8JH22
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

298596:BI350 RS02480
gene id: 298596:BI350_RS02480
uniprot id: A0A1D8JD01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

298596:BI350 RS02310
gene id: 298596:BI350_RS02310
uniprot id: A0A1D8JCW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

298596:BI350 RS13005
gene id: 298596:BI350_RS13005
uniprot id: A0A1D8JI20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

298596:BI350 RS05345
gene id: 298596:BI350_RS05345
uniprot id: A0A1D8JE97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

298596:BI350 RS10640
gene id: 298596:BI350_RS10640
uniprot id: A0A1D8JGX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS14905
gene id: 298596:BI350_RS14905
uniprot id: A0A1D8JJ21
names: Similarity
messages: Belongs to the phosphohexose mutase family.

298596:BI350 RS16445
gene id: 298596:BI350_RS16445
uniprot id: A0A1D8JJU0
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS07995
gene id: 298596:BI350_RS07995
uniprot id: A0A1D8JFJ7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

298596:BI350 RS06920
gene id: 298596:BI350_RS06920
uniprot id: A0A1D8JF08
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

298596:BI350 RS06290
gene id: 298596:BI350_RS06290
uniprot id: A0A1D8JEQ0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

298596:BI350 RS10760
gene id: 298596:BI350_RS10760
uniprot id: A0A1D8JGX5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS11390
gene id: 298596:BI350_RS11390
uniprot id: A0A1D8JH99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

298596:BI350 RS01515
gene id: 298596:BI350_RS01515
uniprot id: A0A1D8JCI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

298596:BI350 RS01985
gene id: 298596:BI350_RS01985
uniprot id: A0A1D8JCQ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS15685
gene id: 298596:BI350_RS15685
uniprot id: A0A1D8JJG1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS08875
gene id: 298596:BI350_RS08875
uniprot id: A0A1D8JFZ6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

298596:BI350 RS12765
gene id: 298596:BI350_RS12765
uniprot id: A0A1D8JHX6
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

298596:BI350 RS04305
gene id: 298596:BI350_RS04305
uniprot id: A0A1D8JDT0
names: Similarity
messages: Belongs to the AHA1 family.

298596:BI350 RS13115
gene id: 298596:BI350_RS13115
uniprot id: A0A1D8JI40
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

298596:BI350 RS14045
gene id: 298596:BI350_RS14045
uniprot id: A0A1D8JIK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

298596:BI350 RS03570
gene id: 298596:BI350_RS03570
uniprot id: A0A1D8JDG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

298596:BI350 RS03765
gene id: 298596:BI350_RS03765
uniprot id: A0A1D8JDK1
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS00155
gene id: 298596:BI350_RS00155
uniprot id: A0A1D8JBX3
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

298596:BI350 RS07155
gene id: 298596:BI350_RS07155
uniprot id: A0A1D8JF80
names: Similarity
messages: Belongs to the ComB family.

298596:BI350 RS12185
gene id: 298596:BI350_RS12185
uniprot id: A0A1D8JHQ8
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS14060
gene id: 298596:BI350_RS14060
uniprot id: A0A1D8JKM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

298596:BI350 RS08820
gene id: 298596:BI350_RS08820
uniprot id: A0A1D8JFY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

298596:BI350 RS07175
gene id: 298596:BI350_RS07175
uniprot id: A0A1D8JF59
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

298596:BI350 RS13510
gene id: 298596:BI350_RS13510
uniprot id: A0A1D8JIA1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

298596:BI350 RS13185
gene id: 298596:BI350_RS13185
uniprot id: A0A1D8JI84
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

298596:BI350 RS05335
gene id: 298596:BI350_RS05335
uniprot id: A0A1D8JEA2
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

298596:BI350 RS12210
gene id: 298596:BI350_RS12210
uniprot id: A0A1D8JHM3
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

298596:BI350 RS01230
gene id: 298596:BI350_RS01230
uniprot id: A0A1D8JCD4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

298596:BI350 RS07765
gene id: 298596:BI350_RS07765
uniprot id: A0A1D8JFG7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

298596:BI350 RS04070
gene id: 298596:BI350_RS04070
uniprot id: A0A1D8JDR7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

298596:BI350 RS12505
gene id: 298596:BI350_RS12505
uniprot id: A0A1D8JHS8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

298596:BI350 RS12935
gene id: 298596:BI350_RS12935
uniprot id: A0A1D8JI13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

298596:BI350 RS15185
gene id: 298596:BI350_RS15185
uniprot id: A0A1D8JJ58
names: Similarity
messages: Belongs to the peptidase C40 family.

298596:BI350 RS02360
gene id: 298596:BI350_RS02360
uniprot id: A0A1D8JCX9
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

298596:BI350 RS08810
gene id: 298596:BI350_RS08810
uniprot id: A0A1D8JFZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

298596:BI350 RS08525
gene id: 298596:BI350_RS08525
uniprot id: A0A1D8JFU0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

298596:BI350 RS12940
gene id: 298596:BI350_RS12940
uniprot id: A0A1D8JI04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

298596:BI350 RS12445
gene id: 298596:BI350_RS12445
uniprot id: A0A1D8JHR5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

298596:BI350 RS13540
gene id: 298596:BI350_RS13540
uniprot id: A0A1D8JIE3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

298596:BI350 RS09930
gene id: 298596:BI350_RS09930
uniprot id: A0A1D8JGH8
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

298596:BI350 RS13885
gene id: 298596:BI350_RS13885
uniprot id: A0A1D8JIH2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

298596:BI350 RS11990
gene id: 298596:BI350_RS11990
uniprot id: A0A1D8JHJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS08065
gene id: 298596:BI350_RS08065
uniprot id: A0A1D8JFK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS14550
gene id: 298596:BI350_RS14550
uniprot id: A0A1D8JIV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS10345
gene id: 298596:BI350_RS10345
uniprot id: A0A1D8JGQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

298596:BI350 RS16215
gene id: 298596:BI350_RS16215
uniprot id: A0A1D8JJQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

298596:BI350 RS03150
gene id: 298596:BI350_RS03150
uniprot id: A0A1D8JDA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

298596:BI350 RS15900
gene id: 298596:BI350_RS15900
uniprot id: A0A1D8JJJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

298596:BI350 RS02905
gene id: 298596:BI350_RS02905
uniprot id: A0A1D8JD71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

298596:BI350 RS15370
gene id: 298596:BI350_RS15370
uniprot id: A0A1D8JJA4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

298596:BI350 RS07645
gene id: 298596:BI350_RS07645
uniprot id: A0A1D8JFD3
names: Similarity
messages: Belongs to the PrpD family.

298596:BI350 RS09030
gene id: 298596:BI350_RS09030
uniprot id: A0A1D8JG33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS09915
gene id: 298596:BI350_RS09915
uniprot id: A0A1D8JGJ9
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

298596:BI350 RS10445
gene id: 298596:BI350_RS10445
uniprot id: A0A1D8JGS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

298596:BI350 RS13095
gene id: 298596:BI350_RS13095
uniprot id: A0A1D8JI42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

298596:BI350 RS12225
gene id: 298596:BI350_RS12225
uniprot id: A0A1D8JHN1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS14840
gene id: 298596:BI350_RS14840
uniprot id: A0A1D8JJ11
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS10240
gene id: 298596:BI350_RS10240
uniprot id: A0A1D8JGM9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

298596:BI350 RS01185
gene id: 298596:BI350_RS01185
uniprot id: A0A1D8JCC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

298596:BI350 RS00145
gene id: 298596:BI350_RS00145
uniprot id: A0A1D8JBX1
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

298596:BI350 RS06900
gene id: 298596:BI350_RS06900
uniprot id: A0A1D8JF10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

298596:BI350 RS10185
gene id: 298596:BI350_RS10185
uniprot id: A0A1D8JGP1
names: Similarity
messages: Belongs to the Fur family.

298596:BI350 RS07015
gene id: 298596:BI350_RS07015
uniprot id: A0A1D8JF25
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

298596:BI350 RS11175
gene id: 298596:BI350_RS11175
uniprot id: A0A1D8JH45
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

298596:BI350 RS14370
gene id: 298596:BI350_RS14370
uniprot id: A0A1D8JIT5
names: Function
names: Similarity
messages: Belongs to the UxaE family.
messages: Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA).

298596:BI350 RS02145
gene id: 298596:BI350_RS02145
uniprot id: A0A1D8JCT8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

298596:BI350 RS13715
gene id: 298596:BI350_RS13715
uniprot id: A0A1D8JIE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

298596:BI350 RS05715
gene id: 298596:BI350_RS05715
uniprot id: A0A1D8JEF4
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS03025
gene id: 298596:BI350_RS03025
uniprot id: A0A1D8JD77
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).

298596:BI350 RS03575
gene id: 298596:BI350_RS03575
uniprot id: A0A1D8JDG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

298596:BI350 RS02030
gene id: 298596:BI350_RS02030
uniprot id: A0A1D8JK35
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

298596:BI350 RS10255
gene id: 298596:BI350_RS10255
uniprot id: A0A1D8JGQ3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

298596:BI350 RS04655
gene id: 298596:BI350_RS04655
uniprot id: A0A1D8JDX8
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

298596:BI350 RS01645
gene id: 298596:BI350_RS01645
uniprot id: A0A1D8JCJ1
names: Similarity
messages: Belongs to the peptidase U62 family.

298596:BI350 RS00760
gene id: 298596:BI350_RS00760
uniprot id: A0A1D8JC62
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

298596:BI350 RS12050
gene id: 298596:BI350_RS12050
uniprot id: A0A1D8JHJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

298596:BI350 RS12655
gene id: 298596:BI350_RS12655
uniprot id: A0A1D8JHX7
names: Similarity
messages: Belongs to the fabD family.

298596:BI350 RS00975
gene id: 298596:BI350_RS00975
uniprot id: A0A1D8JCA4
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

298596:BI350 RS01140
gene id: 298596:BI350_RS01140
uniprot id: A0A1D8JCC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

298596:BI350 RS11495
gene id: 298596:BI350_RS11495
uniprot id: A0A1D8JKK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

298596:BI350 RS04440
gene id: 298596:BI350_RS04440
uniprot id: A0A1D8JDV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

298596:BI350 RS05495
gene id: 298596:BI350_RS05495
uniprot id: A0A1D8JK80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP).
messages: Homotetramer.

298596:BI350 RS09700
gene id: 298596:BI350_RS09700
uniprot id: A0A1D8JGG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

298596:BI350 RS12835
gene id: 298596:BI350_RS12835
uniprot id: A0A1D8JHZ5
names: Subcellular Location Annotation
messages: Cytoplasm

298596:BI350 RS06625
gene id: 298596:BI350_RS06625
uniprot id: A0A1D8JEV8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

298596:BI350 RS08745
gene id: 298596:BI350_RS08745
uniprot id: A0A1D8JFX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

298596:BI350 RS00210
gene id: 298596:BI350_RS00210
uniprot id: A0A1D8JBX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

298596:BI350 RS15410
gene id: 298596:BI350_RS15410
uniprot id: A0A1D8JJA7
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS01520
gene id: 298596:BI350_RS01520
uniprot id: A0A1D8JCI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

298596:BI350 RS08755
gene id: 298596:BI350_RS08755
uniprot id: A0A1D8JFY4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

298596:BI350 RS11530
gene id: 298596:BI350_RS11530
uniprot id: A0A1D8JHC2
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

298596:BI350 RS10015
gene id: 298596:BI350_RS10015
uniprot id: A0A1D8JGI9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

298596:BI350 RS02115
gene id: 298596:BI350_RS02115
uniprot id: A0A1D8JCU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

298596:BI350 RS09300
gene id: 298596:BI350_RS09300
uniprot id: A0A1D8JG60
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS12350
gene id: 298596:BI350_RS12350
uniprot id: A0A1D8JHQ4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

298596:BI350 RS12510
gene id: 298596:BI350_RS12510
uniprot id: A0A1D8JHS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

298596:BI350 RS02150
gene id: 298596:BI350_RS02150
uniprot id: A0A1D8JCU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

298596:BI350 RS04080
gene id: 298596:BI350_RS04080
uniprot id: A0A1D8JK39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS03625
gene id: 298596:BI350_RS03625
uniprot id: A0A1D8JDH0
names: Similarity
messages: Belongs to the peptidase S8 family.

298596:BI350 RS15740
gene id: 298596:BI350_RS15740
uniprot id: A0A1D8JJH0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

298596:BI350 RS05140
gene id: 298596:BI350_RS05140
uniprot id: A0A1D8JE82
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. RocA subfamily.

298596:BI350 RS03535
gene id: 298596:BI350_RS03535
uniprot id: A0A1D8JDJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

298596:BI350 RS13700
gene id: 298596:BI350_RS13700
uniprot id: A0A1D8JIG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

298596:BI350 RS06260
gene id: 298596:BI350_RS06260
uniprot id: A0A1D8JEN7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS12790
gene id: 298596:BI350_RS12790
uniprot id: A0A1D8JHX8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS08855
gene id: 298596:BI350_RS08855
uniprot id: A0A1D8JG12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

298596:BI350 RS06510
gene id: 298596:BI350_RS06510
uniprot id: A0A1D8JET4
names: Similarity
messages: Belongs to the UPF0173 family.

298596:BI350 RS14865
gene id: 298596:BI350_RS14865
uniprot id: A0A1D8JIZ8
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

298596:BI350 RS10180
gene id: 298596:BI350_RS10180
uniprot id: A0A1D8JGM0
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

298596:BI350 RS03815
gene id: 298596:BI350_RS03815
uniprot id: A0A1D8JDK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

298596:BI350 RS08135
gene id: 298596:BI350_RS08135
uniprot id: A0A1D8JFN2
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

298596:BI350 RS04460
gene id: 298596:BI350_RS04460
uniprot id: A0A1D8JDV8
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PpaX family.
messages: Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool.

298596:BI350 RS06835
gene id: 298596:BI350_RS06835
uniprot id: A0A1D8JEZ4
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspI family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

298596:BI350 RS13075
gene id: 298596:BI350_RS13075
uniprot id: A0A1D8JI31
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS04950
gene id: 298596:BI350_RS04950
uniprot id: A0A1D8JE52
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.

298596:BI350 RS07220
gene id: 298596:BI350_RS07220
uniprot id: A0A1D8JF69
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS12690
gene id: 298596:BI350_RS12690
uniprot id: A0A1D8JHZ0
names: Similarity
messages: Belongs to the asp23 family.

298596:BI350 RS05915
gene id: 298596:BI350_RS05915
uniprot id: A0A1D8JK79
names: Similarity
messages: Belongs to the SCO1/2 family.

298596:BI350 RS12125
gene id: 298596:BI350_RS12125
uniprot id: A0A1D8JHL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

298596:BI350 RS03925
gene id: 298596:BI350_RS03925
uniprot id: A0A1D8JDM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

298596:BI350 RS07800
gene id: 298596:BI350_RS07800
uniprot id: A0A1D8JFG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

298596:BI350 RS07205
gene id: 298596:BI350_RS07205
uniprot id: A0A1D8JF54
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

298596:BI350 RS10160
gene id: 298596:BI350_RS10160
uniprot id: A0A1D8JGN5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS07990
gene id: 298596:BI350_RS07990
uniprot id: A0A1D8JFJ5
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS10890
gene id: 298596:BI350_RS10890
uniprot id: A0A1D8JGZ2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

298596:BI350 RS08130
gene id: 298596:BI350_RS08130
uniprot id: A0A1D8JFL4
names: Similarity
messages: Belongs to the YciI family.

298596:BI350 RS02045
gene id: 298596:BI350_RS02045
uniprot id: A0A1D8JCS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

298596:BI350 RS07595
gene id: 298596:BI350_RS07595
uniprot id: A0A1D8JFC2
names: Similarity
messages: Belongs to the PrpD family.

298596:BI350 RS14335
gene id: 298596:BI350_RS14335
uniprot id: A0A1D8JIR8
names: Similarity
messages: Belongs to the FGGY kinase family.

298596:BI350 RS14545
gene id: 298596:BI350_RS14545
uniprot id: A0A1D8JIV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS03840
gene id: 298596:BI350_RS03840
uniprot id: A0A1D8JDK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

298596:BI350 RS09785
gene id: 298596:BI350_RS09785
uniprot id: A0A1D8JGE7
names: Similarity
messages: Belongs to the manganese catalase family.

298596:BI350 RS02585
gene id: 298596:BI350_RS02585
uniprot id: A0A1D8JD27
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

298596:BI350 RS08485
gene id: 298596:BI350_RS08485
uniprot id: A0A1D8JFS8
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

298596:BI350 RS15035
gene id: 298596:BI350_RS15035
uniprot id: A0A1D8JJ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS05800
gene id: 298596:BI350_RS05800
uniprot id: A0A1D8JEF2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

298596:BI350 RS12340
gene id: 298596:BI350_RS12340
uniprot id: A0A1D8JHT9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS14515
gene id: 298596:BI350_RS14515
uniprot id: A0A1D8JIV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

298596:BI350 RS08615
gene id: 298596:BI350_RS08615
uniprot id: A0A1D8JFV0
names: Function
messages: Required for transformation and DNA binding.

298596:BI350 RS08610
gene id: 298596:BI350_RS08610
uniprot id: A0A1D8JFY8
names: Function
messages: Required for transformation and DNA binding.

298596:BI350 RS05835
gene id: 298596:BI350_RS05835
uniprot id: A0A1D8JEI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

298596:BI350 RS01050
gene id: 298596:BI350_RS01050
uniprot id: A0A1D8JCA8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

298596:BI350 RS08870
gene id: 298596:BI350_RS08870
uniprot id: A0A1D8JFZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

298596:BI350 RS00205
gene id: 298596:BI350_RS00205
uniprot id: A0A1D8JBY4
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

298596:BI350 RS04520
gene id: 298596:BI350_RS04520
uniprot id: A0A1D8JDX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

298596:BI350 RS12825
gene id: 298596:BI350_RS12825
uniprot id: A0A1D8JHZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

298596:BI350 RS16460
gene id: 298596:BI350_RS16460
uniprot id: A0A1D8JJW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS10460
gene id: 298596:BI350_RS10460
uniprot id: A0A1D8JGU3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

298596:BI350 RS15705
gene id: 298596:BI350_RS15705
uniprot id: A0A1D8JJI8
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

298596:BI350 RS04810
gene id: 298596:BI350_RS04810
uniprot id: A0A1D8JE12
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

298596:BI350 RS01890
gene id: 298596:BI350_RS01890
uniprot id: A0A1D8JCN8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

298596:BI350 RS08530
gene id: 298596:BI350_RS08530
uniprot id: A0A1D8JFU7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

298596:BI350 RS00125
gene id: 298596:BI350_RS00125
uniprot id: A0A1D8JJV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS02795
gene id: 298596:BI350_RS02795
uniprot id: A0A1D8JD61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS13080
gene id: 298596:BI350_RS13080
uniprot id: A0A1D8JI65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Membrane

298596:BI350 RS10410
gene id: 298596:BI350_RS10410
uniprot id: A0A1D8JGT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

298596:BI350 RS15615
gene id: 298596:BI350_RS15615
uniprot id: A0A1D8JJE7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

298596:BI350 RS11635
gene id: 298596:BI350_RS11635
uniprot id: A0A1D8JHD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS12695
gene id: 298596:BI350_RS12695
uniprot id: A0A1D8JHZ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

298596:BI350 RS10085
gene id: 298596:BI350_RS10085
uniprot id: A0A1D8JGL1
names: Similarity
messages: Belongs to the GSP E family.

298596:BI350 RS02505
gene id: 298596:BI350_RS02505
uniprot id: A0A1D8JD02
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

298596:BI350 RS07585
gene id: 298596:BI350_RS07585
uniprot id: A0A1D8JFC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

298596:BI350 RS04925
gene id: 298596:BI350_RS04925
uniprot id: A0A1D8JE37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

298596:BI350 RS03555
gene id: 298596:BI350_RS03555
uniprot id: A0A1D8JK32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS04065
gene id: 298596:BI350_RS04065
uniprot id: A0A1D8JDP5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

298596:BI350 RS07825
gene id: 298596:BI350_RS07825
uniprot id: A0A1D8JFH3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

298596:BI350 RS16330
gene id: 298596:BI350_RS16330
uniprot id: A0A1D8JJS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS14740
gene id: 298596:BI350_RS14740
uniprot id: A0A1D8JIY7
names: Similarity
messages: Belongs to the peptidase S8 family.

298596:BI350 RS00400
gene id: 298596:BI350_RS00400
uniprot id: A0A1D8JC11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

298596:BI350 RS05940
gene id: 298596:BI350_RS05940
uniprot id: A0A1D8JEJ1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

298596:BI350 RS13655
gene id: 298596:BI350_RS13655
uniprot id: A0A1D8JIF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

298596:BI350 RS02265
gene id: 298596:BI350_RS02265
uniprot id: A0A1D8JCX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

298596:BI350 RS06705
gene id: 298596:BI350_RS06705
uniprot id: A0A1D8JEX5
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

298596:BI350 RS14495
gene id: 298596:BI350_RS14495
uniprot id: A0A1D8JIU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS02920
gene id: 298596:BI350_RS02920
uniprot id: A0A1D8JK20
names: Subcellular Location Annotation
messages: Cell membrane

298596:BI350 RS03165
gene id: 298596:BI350_RS03165
uniprot id: A0A1D8JDB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

298596:BI350 RS16470
gene id: 298596:BI350_RS16470
uniprot id: A0A1D8JJV3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

298596:BI350 RS05965
gene id: 298596:BI350_RS05965
uniprot id: A0A1D8JEI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS06685
gene id: 298596:BI350_RS06685
uniprot id: A0A1D8JEW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

298596:BI350 RS13000
gene id: 298596:BI350_RS13000
uniprot id: A0A1D8JI19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

298596:BI350 RS02760
gene id: 298596:BI350_RS02760
uniprot id: A0A1D8JD58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

298596:BI350 RS02640
gene id: 298596:BI350_RS02640
uniprot id: A0A1D8JD34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

298596:BI350 RS00305
gene id: 298596:BI350_RS00305
uniprot id: A0A1D8JBZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS04255
gene id: 298596:BI350_RS04255
uniprot id: A0A1D8JDS1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

298596:BI350 RS02005
gene id: 298596:BI350_RS02005
uniprot id: A0A1D8JCR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

298596:BI350 RS07685
gene id: 298596:BI350_RS07685
uniprot id: A0A1D8JFE9
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

298596:BI350 RS09305
gene id: 298596:BI350_RS09305
uniprot id: A0A1D8JG76
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS15335
gene id: 298596:BI350_RS15335
uniprot id: A0A1D8JJ99
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

298596:BI350 RS03580
gene id: 298596:BI350_RS03580
uniprot id: A0A1D8JDG2
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

298596:BI350 RS04535
gene id: 298596:BI350_RS04535
uniprot id: A0A1D8JDW7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

298596:BI350 RS02175
gene id: 298596:BI350_RS02175
uniprot id: A0A1D8JCV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

298596:BI350 RS02940
gene id: 298596:BI350_RS02940
uniprot id: A0A1D8JD90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

298596:BI350 RS03680
gene id: 298596:BI350_RS03680
uniprot id: A0A1D8JDH4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

298596:BI350 RS08445
gene id: 298596:BI350_RS08445
uniprot id: A0A1D8JFV2
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS02085
gene id: 298596:BI350_RS02085
uniprot id: A0A1D8JCT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

298596:BI350 RS12550
gene id: 298596:BI350_RS12550
uniprot id: A0A1D8JHU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

298596:BI350 RS05985
gene id: 298596:BI350_RS05985
uniprot id: A0A1D8JEI9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

298596:BI350 RS09110
gene id: 298596:BI350_RS09110
uniprot id: A0A1D8JG35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

298596:BI350 RS02780
gene id: 298596:BI350_RS02780
uniprot id: A0A1D8JD46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

298596:BI350 RS05075
gene id: 298596:BI350_RS05075
uniprot id: A0A1D8JE66
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS10125
gene id: 298596:BI350_RS10125
uniprot id: A0A1D8JGP5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

298596:BI350 RS00875
gene id: 298596:BI350_RS00875
uniprot id: A0A1D8JC80
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

298596:BI350 RS12810
gene id: 298596:BI350_RS12810
uniprot id: A0A1D8JI07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

298596:BI350 RS06800
gene id: 298596:BI350_RS06800
uniprot id: A0A1D8JEY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

298596:BI350 RS13605
gene id: 298596:BI350_RS13605
uniprot id: A0A1D8JIC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS13265
gene id: 298596:BI350_RS13265
uniprot id: A0A1D8JI71
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS05990
gene id: 298596:BI350_RS05990
uniprot id: A0A1D8JEJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

298596:BI350 RS14960
gene id: 298596:BI350_RS14960
uniprot id: A0A1D8JJ22
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

298596:BI350 RS08705
gene id: 298596:BI350_RS08705
uniprot id: A0A1D8JFW9
names: Similarity
messages: Belongs to the UPF0758 family.

298596:BI350 RS12540
gene id: 298596:BI350_RS12540
uniprot id: A0A1D8JHU2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

298596:BI350 RS13145
gene id: 298596:BI350_RS13145
uniprot id: A0A1D8JI51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

298596:BI350 RS05520
gene id: 298596:BI350_RS05520
uniprot id: A0A1D8JEB6
names: Similarity
messages: Belongs to the peptidase M17 family.

298596:BI350 RS12030
gene id: 298596:BI350_RS12030
uniprot id: A0A1D8JHL7
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

298596:BI350 RS01020
gene id: 298596:BI350_RS01020
uniprot id: A0A1D8JC98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

298596:BI350 RS05145
gene id: 298596:BI350_RS05145
uniprot id: A0A1D8JE74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
messages: Catalyzes the interconversion of ornithine to glutamate semialdehyde.
messages: Cytoplasm

298596:BI350 RS03230
gene id: 298596:BI350_RS03230
uniprot id: A0A1D8JK54
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

298596:BI350 RS10235
gene id: 298596:BI350_RS10235
uniprot id: A0A1D8JGR1
names: PTM
messages: Binds 1 heme c group covalently per subunit.

298596:BI350 RS12750
gene id: 298596:BI350_RS12750
uniprot id: A0A1D8JI10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

298596:BI350 RS08710
gene id: 298596:BI350_RS08710
uniprot id: A0A1D8JFW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

298596:BI350 RS12855
gene id: 298596:BI350_RS12855
uniprot id: A0A1D8JHZ2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

298596:BI350 RS14760
gene id: 298596:BI350_RS14760
uniprot id: A0A1D8JIY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

298596:BI350 RS11310
gene id: 298596:BI350_RS11310
uniprot id: A0A1D8JH69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

298596:BI350 RS04600
gene id: 298596:BI350_RS04600
uniprot id: A0A1D8JDX0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

298596:BI350 RS15445
gene id: 298596:BI350_RS15445
uniprot id: A0A1D8JKN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

298596:BI350 RS09055
gene id: 298596:BI350_RS09055
uniprot id: A0A1D8JG34
names: Similarity
messages: Belongs to the catalase family.

298596:BI350 RS11320
gene id: 298596:BI350_RS11320
uniprot id: A0A1D8JH68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

298596:BI350 RS15745
gene id: 298596:BI350_RS15745
uniprot id: A0A1D8JJG6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

298596:BI350 RS03885
gene id: 298596:BI350_RS03885
uniprot id: A0A1D8JDN8
names: Similarity
messages: Belongs to the UPF0229 family.

298596:BI350 RS05465
gene id: 298596:BI350_RS05465
uniprot id: A0A1D8JEC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS00420
gene id: 298596:BI350_RS00420
uniprot id: A0A1D8JC18
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

298596:BI350 RS07715
gene id: 298596:BI350_RS07715
uniprot id: A0A1D8JFF5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

298596:BI350 RS15680
gene id: 298596:BI350_RS15680
uniprot id: A0A1D8JJG3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

298596:BI350 RS03600
gene id: 298596:BI350_RS03600
uniprot id: A0A1D8JDI2
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

298596:BI350 RS14930
gene id: 298596:BI350_RS14930
uniprot id: A0A1D8JKM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS02065
gene id: 298596:BI350_RS02065
uniprot id: A0A1D8JCT1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

298596:BI350 RS01650
gene id: 298596:BI350_RS01650
uniprot id: A0A1D8JCJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

298596:BI350 RS00340
gene id: 298596:BI350_RS00340
uniprot id: A0A1D8JBZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS12405
gene id: 298596:BI350_RS12405
uniprot id: A0A1D8JHV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

298596:BI350 RS11330
gene id: 298596:BI350_RS11330
uniprot id: A0A1D8JH82
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

298596:BI350 RS15380
gene id: 298596:BI350_RS15380
uniprot id: A0A1D8JJC7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

298596:BI350 RS12010
gene id: 298596:BI350_RS12010
uniprot id: A0A1D8JHM4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

298596:BI350 RS00175
gene id: 298596:BI350_RS00175
uniprot id: A0A1D8JBX4
names: Similarity
messages: Belongs to the RibF family.

298596:BI350 RS15885
gene id: 298596:BI350_RS15885
uniprot id: A0A1D8JJL2
names: Similarity
messages: Belongs to the ChdC family. Type 1 subfamily.

298596:BI350 RS05925
gene id: 298596:BI350_RS05925
uniprot id: A0A1D8JEH9
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS10545
gene id: 298596:BI350_RS10545
uniprot id: A0A1D8JGT6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

298596:BI350 RS08560
gene id: 298596:BI350_RS08560
uniprot id: A0A1D8JFU1
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

298596:BI350 RS13600
gene id: 298596:BI350_RS13600
uniprot id: A0A1D8JIF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS11275
gene id: 298596:BI350_RS11275
uniprot id: A0A1D8JH88
names: Similarity
messages: Belongs to the UPF0302 family.

298596:BI350 RS01555
gene id: 298596:BI350_RS01555
uniprot id: A0A1D8JCJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS00880
gene id: 298596:BI350_RS00880
uniprot id: A0A1D8JC82
names: Similarity
messages: Belongs to the RutC family.

298596:BI350 RS02625
gene id: 298596:BI350_RS02625
uniprot id: A0A1D8JD22
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

298596:BI350 RS10110
gene id: 298596:BI350_RS10110
uniprot id: A0A1D8JGK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS09210
gene id: 298596:BI350_RS09210
uniprot id: A0A1D8JG58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

298596:BI350 RS12200
gene id: 298596:BI350_RS12200
uniprot id: A0A1D8JHM5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

298596:BI350 RS14675
gene id: 298596:BI350_RS14675
uniprot id: A0A1D8JIX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS02230
gene id: 298596:BI350_RS02230
uniprot id: A0A1D8JCV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

298596:BI350 RS12985
gene id: 298596:BI350_RS12985
uniprot id: A0A1D8JI26
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

298596:BI350 RS10440
gene id: 298596:BI350_RS10440
uniprot id: A0A1D8JGV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

298596:BI350 RS09845
gene id: 298596:BI350_RS09845
uniprot id: A0A1D8JGI1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

298596:BI350 RS16270
gene id: 298596:BI350_RS16270
uniprot id: A0A1D8JJU3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

298596:BI350 RS06995
gene id: 298596:BI350_RS06995
uniprot id: A0A1D8JF42
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

298596:BI350 RS02995
gene id: 298596:BI350_RS02995
uniprot id: A0A1D8JD80
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

298596:BI350 RS08920
gene id: 298596:BI350_RS08920
uniprot id: A0A1D8JG16
names: Similarity
messages: Belongs to the ABC transporter superfamily.

298596:BI350 RS01765
gene id: 298596:BI350_RS01765
uniprot id: A0A1D8JCL1
names: Similarity
messages: Belongs to the asparaginase 1 family.

298596:BI350 RS14805
gene id: 298596:BI350_RS14805
uniprot id: A0A1D8JIZ9
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

298596:BI350 RS01845
gene id: 298596:BI350_RS01845
uniprot id: A0A1D8JCP2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS04610
gene id: 298596:BI350_RS04610
uniprot id: A0A1D8JK70
names: Similarity
messages: Belongs to the HepT RNase toxin family.

298596:BI350 RS15570
gene id: 298596:BI350_RS15570
uniprot id: A0A1D8JJD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

298596:BI350 RS07660
gene id: 298596:BI350_RS07660
uniprot id: A0A1D8JFD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

298596:BI350 RS08385
gene id: 298596:BI350_RS08385
uniprot id: A0A1D8JKC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Membrane

298596:BI350 RS08660
gene id: 298596:BI350_RS08660
uniprot id: A0A1D8JFZ9
names: Similarity
messages: Belongs to the GSP E family.

298596:BI350 RS14285
gene id: 298596:BI350_RS14285
uniprot id: A0A1D8JIR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS01990
gene id: 298596:BI350_RS01990
uniprot id: A0A1D8JCQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

298596:BI350 RS04620
gene id: 298596:BI350_RS04620
uniprot id: A0A1D8JDY7
names: Similarity
messages: Belongs to the EamA transporter family.

298596:BI350 RS01055
gene id: 298596:BI350_RS01055
uniprot id: A0A1D8JCB5
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

298596:BI350 RS02075
gene id: 298596:BI350_RS02075
uniprot id: A0A1D8JCT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

298596:BI350 RS07590
gene id: 298596:BI350_RS07590
uniprot id: A0A1D8JFE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

298596:BI350 RS15390
gene id: 298596:BI350_RS15390
uniprot id: A0A1D8JJB9
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS02110
gene id: 298596:BI350_RS02110
uniprot id: A0A1D8JCU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

298596:BI350 RS04720
gene id: 298596:BI350_RS04720
uniprot id: A0A1D8JE05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS03670
gene id: 298596:BI350_RS03670
uniprot id: A0A1D8JDK5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

298596:BI350 RS08940
gene id: 298596:BI350_RS08940
uniprot id: A0A1D8JG10
names: Cofactor
messages: Can also use Mn(2+) ion.

298596:BI350 RS14295
gene id: 298596:BI350_RS14295
uniprot id: A0A1D8JIR6
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

298596:BI350 RS10495
gene id: 298596:BI350_RS10495
uniprot id: A0A1D8JGV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

298596:BI350 RS05325
gene id: 298596:BI350_RS05325
uniprot id: A0A1D8JE84
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS12325
gene id: 298596:BI350_RS12325
uniprot id: A0A1D8JHP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

298596:BI350 RS04475
gene id: 298596:BI350_RS04475
uniprot id: A0A1D8JDY4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

298596:BI350 RS11375
gene id: 298596:BI350_RS11375
uniprot id: A0A1D8JHA9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

298596:BI350 RS12885
gene id: 298596:BI350_RS12885
uniprot id: A0A1D8JHZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

298596:BI350 RS02130
gene id: 298596:BI350_RS02130
uniprot id: A0A1D8JCT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

298596:BI350 RS11555
gene id: 298596:BI350_RS11555
uniprot id: A0A1D8JHC6
names: Similarity
messages: Belongs to the Fur family.

298596:BI350 RS12980
gene id: 298596:BI350_RS12980
uniprot id: A0A1D8JI22
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

298596:BI350 RS03585
gene id: 298596:BI350_RS03585
uniprot id: A0A1D8JDJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

298596:BI350 RS01510
gene id: 298596:BI350_RS01510
uniprot id: A0A1D8JCI6
names: Similarity
messages: Belongs to the TrpF family.

298596:BI350 RS15150
gene id: 298596:BI350_RS15150
uniprot id: A0A1D8JJ67
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS00750
gene id: 298596:BI350_RS00750
uniprot id: A0A1D8JC59
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

298596:BI350 RS12895
gene id: 298596:BI350_RS12895
uniprot id: A0A1D8JHZ6
names: Similarity
messages: Belongs to the UPF0749 family.

298596:BI350 RS13245
gene id: 298596:BI350_RS13245
uniprot id: A0A1D8JI60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

298596:BI350 RS05375
gene id: 298596:BI350_RS05375
uniprot id: A0A1D8JE94
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS02565
gene id: 298596:BI350_RS02565
uniprot id: A0A1D8JD14
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

298596:BI350 RS11445
gene id: 298596:BI350_RS11445
uniprot id: A0A1D8JH96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

298596:BI350 RS03155
gene id: 298596:BI350_RS03155
uniprot id: A0A1D8JDA2
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

298596:BI350 RS09835
gene id: 298596:BI350_RS09835
uniprot id: A0A1D8JGF8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

298596:BI350 RS11640
gene id: 298596:BI350_RS11640
uniprot id: A0A1D8JHE6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

298596:BI350 RS10720
gene id: 298596:BI350_RS10720
uniprot id: A0A1D8JGZ5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

298596:BI350 RS03645
gene id: 298596:BI350_RS03645
uniprot id: A0A1D8JDJ0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

298596:BI350 RS12270
gene id: 298596:BI350_RS12270
uniprot id: A0A1D8JHN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

298596:BI350 RS02460
gene id: 298596:BI350_RS02460
uniprot id: A0A1D8JCZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

298596:BI350 RS14875
gene id: 298596:BI350_RS14875
uniprot id: A0A1D8JJ12
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

298596:BI350 RS12745
gene id: 298596:BI350_RS12745
uniprot id: A0A1D8JI05
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS02595
gene id: 298596:BI350_RS02595
uniprot id: A0A1D8JD19
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

298596:BI350 RS00475
gene id: 298596:BI350_RS00475
uniprot id: A0A1D8JC30
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS16005
gene id: 298596:BI350_RS16005
uniprot id: A0A1D8JJL4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS09555
gene id: 298596:BI350_RS09555
uniprot id: A0A1D8JGB1
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

298596:BI350 RS06895
gene id: 298596:BI350_RS06895
uniprot id: A0A1D8JF07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

298596:BI350 RS15385
gene id: 298596:BI350_RS15385
uniprot id: A0A1D8JJA8
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS02185
gene id: 298596:BI350_RS02185
uniprot id: A0A1D8JCV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

298596:BI350 RS05120
gene id: 298596:BI350_RS05120
uniprot id: A0A1D8JE77
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS07790
gene id: 298596:BI350_RS07790
uniprot id: A0A1D8JFG4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

298596:BI350 RS09240
gene id: 298596:BI350_RS09240
uniprot id: A0A1D8JG64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

298596:BI350 RS02270
gene id: 298596:BI350_RS02270
uniprot id: A0A1D8JCW9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

298596:BI350 RS13220
gene id: 298596:BI350_RS13220
uniprot id: A0A1D8JI57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

298596:BI350 RS07905
gene id: 298596:BI350_RS07905
uniprot id: A0A1D8JFI4
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

298596:BI350 RS15580
gene id: 298596:BI350_RS15580
uniprot id: A0A1D8JJD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

298596:BI350 RS00115
gene id: 298596:BI350_RS00115
uniprot id: A0A1D8JBV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

298596:BI350 RS04555
gene id: 298596:BI350_RS04555
uniprot id: A0A1D8JDX9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

298596:BI350 RS15775
gene id: 298596:BI350_RS15775
uniprot id: A0A1D8JJI6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

298596:BI350 RS09010
gene id: 298596:BI350_RS09010
uniprot id: A0A1D8JG29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

298596:BI350 RS01205
gene id: 298596:BI350_RS01205
uniprot id: A0A1D8JCC8
names: Similarity
messages: Belongs to the ParB family.

298596:BI350 RS00310
gene id: 298596:BI350_RS00310
uniprot id: A0A1D8JC06
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

298596:BI350 RS00470
gene id: 298596:BI350_RS00470
uniprot id: A0A1D8JC32
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

298596:BI350 RS16210
gene id: 298596:BI350_RS16210
uniprot id: A0A1D8JJT0
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

298596:BI350 RS12415
gene id: 298596:BI350_RS12415
uniprot id: A0A1D8JHR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

298596:BI350 RS06465
gene id: 298596:BI350_RS06465
uniprot id: A0A1D8JEW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS02970
gene id: 298596:BI350_RS02970
uniprot id: A0A1D8JD81
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS01075
gene id: 298596:BI350_RS01075
uniprot id: A0A1D8JCA9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

298596:BI350 RS16030
gene id: 298596:BI350_RS16030
uniprot id: A0A1D8JJM2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

298596:BI350 RS08110
gene id: 298596:BI350_RS08110
uniprot id: A0A1D8JFN0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

298596:BI350 RS13270
gene id: 298596:BI350_RS13270
uniprot id: A0A1D8JI61
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

298596:BI350 RS01045
gene id: 298596:BI350_RS01045
uniprot id: A0A1D8JJX7
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

298596:BI350 RS09920
gene id: 298596:BI350_RS09920
uniprot id: A0A1D8JGG2
names: Similarity
messages: Belongs to the asp23 family.

298596:BI350 RS04455
gene id: 298596:BI350_RS04455
uniprot id: A0A1D8JDW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

298596:BI350 RS13415
gene id: 298596:BI350_RS13415
uniprot id: A0A1D8JIC1
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. YjcG family.

298596:BI350 RS11235
gene id: 298596:BI350_RS11235
uniprot id: A0A1D8JH70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

298596:BI350 RS01580
gene id: 298596:BI350_RS01580
uniprot id: A0A1D8JCJ4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

298596:BI350 RS09070
gene id: 298596:BI350_RS09070
uniprot id: A0A1D8JG41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

298596:BI350 RS09025
gene id: 298596:BI350_RS09025
uniprot id: A0A1D8JG28
names: Similarity
messages: Belongs to the ABC transporter superfamily.

298596:BI350 RS13200
gene id: 298596:BI350_RS13200
uniprot id: A0A1D8JI63
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

298596:BI350 RS09175
gene id: 298596:BI350_RS09175
uniprot id: A0A1D8JG43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

298596:BI350 RS06495
gene id: 298596:BI350_RS06495
uniprot id: A0A1D8JEV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

298596:BI350 RS03610
gene id: 298596:BI350_RS03610
uniprot id: A0A1D8JDK3
names: Similarity
messages: Belongs to the GARS family.

298596:BI350 RS13120
gene id: 298596:BI350_RS13120
uniprot id: A0A1D8JI70
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS00120
gene id: 298596:BI350_RS00120
uniprot id: A0A1D8JBW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS06565
gene id: 298596:BI350_RS06565
uniprot id: A0A1D8JEU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

298596:BI350 RS08300
gene id: 298596:BI350_RS08300
uniprot id: A0A1D8JFR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS03125
gene id: 298596:BI350_RS03125
uniprot id: A0A1D8JDA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

298596:BI350 RS08330
gene id: 298596:BI350_RS08330
uniprot id: A0A1D8JFT8
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS11585
gene id: 298596:BI350_RS11585
uniprot id: A0A1D8JHC1
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

298596:BI350 RS09365
gene id: 298596:BI350_RS09365
uniprot id: A0A1D8JG86
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

298596:BI350 RS05900
gene id: 298596:BI350_RS05900
uniprot id: A0A1D8JEI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

298596:BI350 RS07835
gene id: 298596:BI350_RS07835
uniprot id: A0A1D8JFG8
names: Subcellular Location Annotation
messages: Cytoplasm

298596:BI350 RS04840
gene id: 298596:BI350_RS04840
uniprot id: A0A1D8JE24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

298596:BI350 RS14520
gene id: 298596:BI350_RS14520
uniprot id: A0A1D8JIT8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

298596:BI350 RS05960
gene id: 298596:BI350_RS05960
uniprot id: A0A1D8JEJ7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

298596:BI350 RS06760
gene id: 298596:BI350_RS06760
uniprot id: A0A1D8JEY4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

298596:BI350 RS10040
gene id: 298596:BI350_RS10040
uniprot id: A0A1D8JGI2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

298596:BI350 RS12250
gene id: 298596:BI350_RS12250
uniprot id: A0A1D8JHN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

298596:BI350 RS02165
gene id: 298596:BI350_RS02165
uniprot id: A0A1D8JCV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

298596:BI350 RS04760
gene id: 298596:BI350_RS04760
uniprot id: A0A1D8JE06
names: Similarity
messages: Belongs to the bacterial solute-binding protein 8 family.

298596:BI350 RS11210
gene id: 298596:BI350_RS11210
uniprot id: A0A1D8JKH1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

298596:BI350 RS06150
gene id: 298596:BI350_RS06150
uniprot id: A0A1D8JEM5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS05740
gene id: 298596:BI350_RS05740
uniprot id: A0A1D8JEE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS12400
gene id: 298596:BI350_RS12400
uniprot id: A0A1D8JHU4
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

298596:BI350 RS14915
gene id: 298596:BI350_RS14915
uniprot id: A0A1D8JJ08
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS07195
gene id: 298596:BI350_RS07195
uniprot id: A0A1D8JF64
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

298596:BI350 RS02650
gene id: 298596:BI350_RS02650
uniprot id: A0A1D8JD31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

298596:BI350 RS04685
gene id: 298596:BI350_RS04685
uniprot id: A0A1D8JE21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

298596:BI350 RS14535
gene id: 298596:BI350_RS14535
uniprot id: A0A1D8JIV6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

298596:BI350 RS00445
gene id: 298596:BI350_RS00445
uniprot id: A0A1D8JC25
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS10415
gene id: 298596:BI350_RS10415
uniprot id: A0A1D8JGQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

298596:BI350 RS11515
gene id: 298596:BI350_RS11515
uniprot id: A0A1D8JHE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

298596:BI350 RS05995
gene id: 298596:BI350_RS05995
uniprot id: A0A1D8JEK7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS15305
gene id: 298596:BI350_RS15305
uniprot id: A0A1D8JJ94
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

298596:BI350 RS01105
gene id: 298596:BI350_RS01105
uniprot id: A0A1D8JCB6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

298596:BI350 RS03510
gene id: 298596:BI350_RS03510
uniprot id: A0A1D8JDH2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS02910
gene id: 298596:BI350_RS02910
uniprot id: A0A1D8JD79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

298596:BI350 RS16225
gene id: 298596:BI350_RS16225
uniprot id: A0A1D8JJR9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS10145
gene id: 298596:BI350_RS10145
uniprot id: A0A1D8JGN4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

298596:BI350 RS04765
gene id: 298596:BI350_RS04765
uniprot id: A0A1D8JE28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

298596:BI350 RS12725
gene id: 298596:BI350_RS12725
uniprot id: A0A1D8JHW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

298596:BI350 RS12425
gene id: 298596:BI350_RS12425
uniprot id: A0A1D8JHS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

298596:BI350 RS05030
gene id: 298596:BI350_RS05030
uniprot id: A0A1D8JE59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS14040
gene id: 298596:BI350_RS14040
uniprot id: A0A1D8JIM8
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS01130
gene id: 298596:BI350_RS01130
uniprot id: A0A1D8JCB7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

298596:BI350 RS00895
gene id: 298596:BI350_RS00895
uniprot id: A0A1D8JC84
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

298596:BI350 RS05500
gene id: 298596:BI350_RS05500
uniprot id: A0A1D8JK59
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS05350
gene id: 298596:BI350_RS05350
uniprot id: A0A1D8JE96
names: Similarity
messages: Belongs to the Dps family.

298596:BI350 RS14870
gene id: 298596:BI350_RS14870
uniprot id: A0A1D8JJ18
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

298596:BI350 RS09165
gene id: 298596:BI350_RS09165
uniprot id: A0A1D8JG69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS09440
gene id: 298596:BI350_RS09440
uniprot id: A0A1D8JG87
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS10190
gene id: 298596:BI350_RS10190
uniprot id: A0A1D8JGN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS12805
gene id: 298596:BI350_RS12805
uniprot id: A0A1D8JHY2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

298596:BI350 RS00560
gene id: 298596:BI350_RS00560
uniprot id: A0A1D8JC38
names: Subcellular Location Annotation
messages: Periplasm

298596:BI350 RS15460
gene id: 298596:BI350_RS15460
uniprot id: A0A1D8JJC1
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS09405
gene id: 298596:BI350_RS09405
uniprot id: A0A1D8JGA4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

298596:BI350 RS06790
gene id: 298596:BI350_RS06790
uniprot id: A0A1D8JEY5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

298596:BI350 RS02240
gene id: 298596:BI350_RS02240
uniprot id: A0A1D8JCW3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

298596:BI350 RS04800
gene id: 298596:BI350_RS04800
uniprot id: A0A1D8JE40
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

298596:BI350 RS05040
gene id: 298596:BI350_RS05040
uniprot id: A0A1D8JE67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

298596:BI350 RS04545
gene id: 298596:BI350_RS04545
uniprot id: A0A1D8JDY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

298596:BI350 RS02670
gene id: 298596:BI350_RS02670
uniprot id: A0A1D8JD28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

298596:BI350 RS15965
gene id: 298596:BI350_RS15965
uniprot id: A0A1D8JJK4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS12255
gene id: 298596:BI350_RS12255
uniprot id: A0A1D8JHQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

298596:BI350 RS00575
gene id: 298596:BI350_RS00575
uniprot id: A0A1D8JJW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS02190
gene id: 298596:BI350_RS02190
uniprot id: A0A1D8JCV3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

298596:BI350 RS07930
gene id: 298596:BI350_RS07930
uniprot id: A0A1D8JFJ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

298596:BI350 RS09960
gene id: 298596:BI350_RS09960
uniprot id: A0A1D8JGK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

298596:BI350 RS07620
gene id: 298596:BI350_RS07620
uniprot id: A0A1D8JFD9
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS14855
gene id: 298596:BI350_RS14855
uniprot id: A0A1D8JJ16
names: Similarity
messages: Belongs to the UPF0047 family.

298596:BI350 RS15695
gene id: 298596:BI350_RS15695
uniprot id: A0A1D8JKN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS15250
gene id: 298596:BI350_RS15250
uniprot id: A0A1D8JJ89
names: Similarity
messages: Belongs to the peptidase S8 family.

298596:BI350 RS03690
gene id: 298596:BI350_RS03690
uniprot id: A0A1D8JDK9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

298596:BI350 RS09660
gene id: 298596:BI350_RS09660
uniprot id: A0A1D8JGE6
names: Similarity
messages: Belongs to the SCO1/2 family.

298596:BI350 RS09310
gene id: 298596:BI350_RS09310
uniprot id: A0A1D8JG85
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

298596:BI350 RS10430
gene id: 298596:BI350_RS10430
uniprot id: A0A1D8JGR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

298596:BI350 RS15855
gene id: 298596:BI350_RS15855
uniprot id: A0A1D8JJJ0
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

298596:BI350 RS06095
gene id: 298596:BI350_RS06095
uniprot id: A0A1D8JEL8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

298596:BI350 RS13650
gene id: 298596:BI350_RS13650
uniprot id: A0A1D8JID4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS04715
gene id: 298596:BI350_RS04715
uniprot id: A0A1D8JDZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS11525
gene id: 298596:BI350_RS11525
uniprot id: A0A1D8JHB5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

298596:BI350 RS04905
gene id: 298596:BI350_RS04905
uniprot id: A0A1D8JE34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS14490
gene id: 298596:BI350_RS14490
uniprot id: A0A1D8JIT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS12590
gene id: 298596:BI350_RS12590
uniprot id: A0A1D8JHW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS12545
gene id: 298596:BI350_RS12545
uniprot id: A0A1D8JKK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

298596:BI350 RS14510
gene id: 298596:BI350_RS14510
uniprot id: A0A1D8JIU2
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

298596:BI350 RS15585
gene id: 298596:BI350_RS15585
uniprot id: A0A1D8JJF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

298596:BI350 RS01980
gene id: 298596:BI350_RS01980
uniprot id: A0A1D8JCR5
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

298596:BI350 RS00765
gene id: 298596:BI350_RS00765
uniprot id: A0A1D8JJX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

298596:BI350 RS07725
gene id: 298596:BI350_RS07725
uniprot id: A0A1D8JFE5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

298596:BI350 RS05165
gene id: 298596:BI350_RS05165
uniprot id: A0A1D8JE87
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS03130
gene id: 298596:BI350_RS03130
uniprot id: A0A1D8JD89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

298596:BI350 RS00415
gene id: 298596:BI350_RS00415
uniprot id: A0A1D8JC24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
messages: Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
messages: Cytoplasm

298596:BI350 RS00370
gene id: 298596:BI350_RS00370
uniprot id: A0A1D8JC08
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS12815
gene id: 298596:BI350_RS12815
uniprot id: A0A1D8JHY7
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

298596:BI350 RS07655
gene id: 298596:BI350_RS07655
uniprot id: A0A1D8JFD5
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

298596:BI350 RS16515
gene id: 298596:BI350_RS16515
uniprot id: A0A1D8JJV5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

298596:BI350 RS01720
gene id: 298596:BI350_RS01720
uniprot id: A0A1D8JK02
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

298596:BI350 RS02840
gene id: 298596:BI350_RS02840
uniprot id: A0A1D8JD52
names: Similarity
messages: Belongs to the DtxR/MntR family.

298596:BI350 RS05745
gene id: 298596:BI350_RS05745
uniprot id: A0A1D8JEF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS04365
gene id: 298596:BI350_RS04365
uniprot id: A0A1D8JDT7
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

298596:BI350 RS12555
gene id: 298596:BI350_RS12555
uniprot id: A0A1D8JHT8
names: Similarity
messages: Belongs to the DprA/Smf family.

298596:BI350 RS10755
gene id: 298596:BI350_RS10755
uniprot id: A0A1D8JGX2
names: Similarity
messages: Belongs to the EamA transporter family.

298596:BI350 RS02140
gene id: 298596:BI350_RS02140
uniprot id: A0A1D8JCU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

298596:BI350 RS14955
gene id: 298596:BI350_RS14955
uniprot id: A0A1D8JJ44
names: Similarity
messages: Belongs to the EamA transporter family.

298596:BI350 RS08555
gene id: 298596:BI350_RS08555
uniprot id: A0A1D8JKD1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

298596:BI350 RS12755
gene id: 298596:BI350_RS12755
uniprot id: A0A1D8JHX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

298596:BI350 RS02830
gene id: 298596:BI350_RS02830
uniprot id: A0A1D8JD59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

298596:BI350 RS12845
gene id: 298596:BI350_RS12845
uniprot id: A0A1D8JI23
names: Similarity
messages: Belongs to the YggT family.

298596:BI350 RS13720
gene id: 298596:BI350_RS13720
uniprot id: A0A1D8JIG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

298596:BI350 RS02755
gene id: 298596:BI350_RS02755
uniprot id: A0A1D8JD56
names: Similarity
messages: Belongs to the UPF0312 family.

298596:BI350 RS05570
gene id: 298596:BI350_RS05570
uniprot id: A0A1D8JED7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

298596:BI350 RS05820
gene id: 298596:BI350_RS05820
uniprot id: A0A1D8JEJ4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

298596:BI350 RS14410
gene id: 298596:BI350_RS14410
uniprot id: A0A1D8JIR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS02215
gene id: 298596:BI350_RS02215
uniprot id: A0A1D8JCX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

298596:BI350 RS01960
gene id: 298596:BI350_RS01960
uniprot id: A0A1D8JCR4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS07885
gene id: 298596:BI350_RS07885
uniprot id: A0A1D8JFH7
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS08890
gene id: 298596:BI350_RS08890
uniprot id: A0A1D8JFZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

298596:BI350 RS09445
gene id: 298596:BI350_RS09445
uniprot id: A0A1D8JKH2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

298596:BI350 RS01560
gene id: 298596:BI350_RS01560
uniprot id: A0A1D8JCJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS01855
gene id: 298596:BI350_RS01855
uniprot id: A0A1D8JCP3
names: Similarity
messages: Belongs to the ThiD family.

298596:BI350 RS13750
gene id: 298596:BI350_RS13750
uniprot id: A0A1D8JIE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

298596:BI350 RS09740
gene id: 298596:BI350_RS09740
uniprot id: A0A1D8JGG1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.
messages: Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS08455
gene id: 298596:BI350_RS08455
uniprot id: A0A1D8JFS0
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

298596:BI350 RS03590
gene id: 298596:BI350_RS03590
uniprot id: A0A1D8JDI1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

298596:BI350 RS12915
gene id: 298596:BI350_RS12915
uniprot id: A0A1D8JI01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

298596:BI350 RS04930
gene id: 298596:BI350_RS04930
uniprot id: A0A1D8JE35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

298596:BI350 RS02820
gene id: 298596:BI350_RS02820
uniprot id: A0A1D8JD65
names: Similarity
messages: Belongs to the peptidase S58 family.

298596:BI350 RS02445
gene id: 298596:BI350_RS02445
uniprot id: A0A1D8JCZ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS09380
gene id: 298596:BI350_RS09380
uniprot id: A0A1D8JKH6
names: Similarity
messages: Belongs to the EamA transporter family.

298596:BI350 RS01305
gene id: 298596:BI350_RS01305
uniprot id: A0A1D8JCE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS12950
gene id: 298596:BI350_RS12950
uniprot id: A0A1D8JI08
names: Function
names: Similarity
messages: Belongs to the BshC family.
messages: Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.

298596:BI350 RS03145
gene id: 298596:BI350_RS03145
uniprot id: A0A1D8JD98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

298596:BI350 RS03955
gene id: 298596:BI350_RS03955
uniprot id: A0A1D8JDM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

298596:BI350 RS11140
gene id: 298596:BI350_RS11140
uniprot id: A0A1D8JH56
names: Subcellular Location Annotation
messages: Cytoplasm

298596:BI350 RS09725
gene id: 298596:BI350_RS09725
uniprot id: A0A1D8JGG3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

298596:BI350 RS06765
gene id: 298596:BI350_RS06765
uniprot id: A0A1D8JEY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

298596:BI350 RS13215
gene id: 298596:BI350_RS13215
uniprot id: A0A1D8JI50
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

298596:BI350 RS00220
gene id: 298596:BI350_RS00220
uniprot id: A0A1D8JBY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS05305
gene id: 298596:BI350_RS05305
uniprot id: A0A1D8JE83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

298596:BI350 RS09095
gene id: 298596:BI350_RS09095
uniprot id: A0A1D8JG48
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

298596:BI350 RS12095
gene id: 298596:BI350_RS12095
uniprot id: A0A1D8JHK2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

298596:BI350 RS09485
gene id: 298596:BI350_RS09485
uniprot id: A0A1D8JGA3
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

298596:BI350 RS07425
gene id: 298596:BI350_RS07425
uniprot id: A0A1D8JF97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

298596:BI350 RS07510
gene id: 298596:BI350_RS07510
uniprot id: A0A1D8JFB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS06110
gene id: 298596:BI350_RS06110
uniprot id: A0A1D8JEK9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

298596:BI350 RS01740
gene id: 298596:BI350_RS01740
uniprot id: A0A1D8JCM3
names: Similarity
messages: Belongs to the peptidase S11 family.

298596:BI350 RS03895
gene id: 298596:BI350_RS03895
uniprot id: A0A1D8JDP6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

298596:BI350 RS00255
gene id: 298596:BI350_RS00255
uniprot id: A0A1D8JBZ6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

298596:BI350 RS10620
gene id: 298596:BI350_RS10620
uniprot id: A0A1D8JGV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

298596:BI350 RS01750
gene id: 298596:BI350_RS01750
uniprot id: A0A1D8JCM5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

298596:BI350 RS12090
gene id: 298596:BI350_RS12090
uniprot id: A0A1D8JHK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

298596:BI350 RS10705
gene id: 298596:BI350_RS10705
uniprot id: A0A1D8JGW7
names: Subcellular Location Annotation
messages: Cytoplasm

298596:BI350 RS14200
gene id: 298596:BI350_RS14200
uniprot id: A0A1D8JIQ0
names: Similarity
messages: Belongs to the proline racemase family.

298596:BI350 RS06075
gene id: 298596:BI350_RS06075
uniprot id: A0A1D8JEN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

298596:BI350 RS08950
gene id: 298596:BI350_RS08950
uniprot id: A0A1D8JG26
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS04880
gene id: 298596:BI350_RS04880
uniprot id: A0A1D8JE26
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

298596:BI350 RS11340
gene id: 298596:BI350_RS11340
uniprot id: A0A1D8JH90
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

298596:BI350 RS02170
gene id: 298596:BI350_RS02170
uniprot id: A0A1D8JCU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

298596:BI350 RS07805
gene id: 298596:BI350_RS07805
uniprot id: A0A1D8JFG5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS13640
gene id: 298596:BI350_RS13640
uniprot id: A0A1D8JIG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

298596:BI350 RS10020
gene id: 298596:BI350_RS10020
uniprot id: A0A1D8JGL3
names: Subcellular Location Annotation
messages: Cell membrane

298596:BI350 RS06195
gene id: 298596:BI350_RS06195
uniprot id: A0A1D8JEP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

298596:BI350 RS12520
gene id: 298596:BI350_RS12520
uniprot id: A0A1D8JHW2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

298596:BI350 RS02080
gene id: 298596:BI350_RS02080
uniprot id: A0A1D8JCS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

298596:BI350 RS05365
gene id: 298596:BI350_RS05365
uniprot id: A0A1D8JE95
names: Similarity
messages: Belongs to the Nudix hydrolase family.

298596:BI350 RS13695
gene id: 298596:BI350_RS13695
uniprot id: A0A1D8JID8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

298596:BI350 RS06375
gene id: 298596:BI350_RS06375
uniprot id: A0A1D8JET7
names: Similarity
messages: Belongs to the histone deacetylase family.

298596:BI350 RS16505
gene id: 298596:BI350_RS16505
uniprot id: A0A1D8JJU9
names: Subcellular Location Annotation
messages: Cell membrane

298596:BI350 RS13545
gene id: 298596:BI350_RS13545
uniprot id: A0A1D8JIB8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

298596:BI350 RS01630
gene id: 298596:BI350_RS01630
uniprot id: A0A1D8JCK3
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS02155
gene id: 298596:BI350_RS02155
uniprot id: A0A1D8JCT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

298596:BI350 RS11460
gene id: 298596:BI350_RS11460
uniprot id: A0A1D8JHD2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS12320
gene id: 298596:BI350_RS12320
uniprot id: A0A1D8JHP4
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS09550
gene id: 298596:BI350_RS09550
uniprot id: A0A1D8JGA0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

298596:BI350 RS11580
gene id: 298596:BI350_RS11580
uniprot id: A0A1D8JHG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

298596:BI350 RS10455
gene id: 298596:BI350_RS10455
uniprot id: A0A1D8JGS8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

298596:BI350 RS15755
gene id: 298596:BI350_RS15755
uniprot id: A0A1D8JJJ7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

298596:BI350 RS09880
gene id: 298596:BI350_RS09880
uniprot id: A0A1D8JGG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

298596:BI350 RS03615
gene id: 298596:BI350_RS03615
uniprot id: A0A1D8JDJ8
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

298596:BI350 RS06175
gene id: 298596:BI350_RS06175
uniprot id: A0A1D8JEM0
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

298596:BI350 RS01575
gene id: 298596:BI350_RS01575
uniprot id: A0A1D8JJZ0
names: Similarity
messages: Belongs to the peptidase S66 family.

298596:BI350 RS07265
gene id: 298596:BI350_RS07265
uniprot id: A0A1D8JF68
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS06980
gene id: 298596:BI350_RS06980
uniprot id: A0A1D8JF19
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

298596:BI350 RS07855
gene id: 298596:BI350_RS07855
uniprot id: A0A1D8JFH5
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS10575
gene id: 298596:BI350_RS10575
uniprot id: A0A1D8JGW4
names: Similarity
messages: Belongs to the UPF0297 family.

298596:BI350 RS01900
gene id: 298596:BI350_RS01900
uniprot id: A0A1D8JCQ0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

298596:BI350 RS04495
gene id: 298596:BI350_RS04495
uniprot id: A0A1D8JDX7
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

298596:BI350 RS10325
gene id: 298596:BI350_RS10325
uniprot id: A0A1D8JGR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

298596:BI350 RS02245
gene id: 298596:BI350_RS02245
uniprot id: A0A1D8JCV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

298596:BI350 RS08720
gene id: 298596:BI350_RS08720
uniprot id: A0A1D8JFW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

298596:BI350 RS04010
gene id: 298596:BI350_RS04010
uniprot id: A0A1D8JDP2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS08765
gene id: 298596:BI350_RS08765
uniprot id: A0A1D8JFX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

298596:BI350 RS15345
gene id: 298596:BI350_RS15345
uniprot id: A0A1D8JJ95
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS06350
gene id: 298596:BI350_RS06350
uniprot id: A0A1D8JET3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

298596:BI350 RS15970
gene id: 298596:BI350_RS15970
uniprot id: A0A1D8JJK7
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

298596:BI350 RS03110
gene id: 298596:BI350_RS03110
uniprot id: A0A1D8JDB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

298596:BI350 RS13880
gene id: 298596:BI350_RS13880
uniprot id: A0A1D8JIK3
names: Similarity
messages: Belongs to the bacterial flagellin family.

298596:BI350 RS10920
gene id: 298596:BI350_RS10920
uniprot id: A0A1D8JH20
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

298596:BI350 RS05020
gene id: 298596:BI350_RS05020
uniprot id: A0A1D8JE53
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

298596:BI350 RS05760
gene id: 298596:BI350_RS05760
uniprot id: A0A1D8JEI3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

298596:BI350 RS00360
gene id: 298596:BI350_RS00360
uniprot id: A0A1D8JC02
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

298596:BI350 RS07865
gene id: 298596:BI350_RS07865
uniprot id: A0A1D8JFJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

298596:BI350 RS01640
gene id: 298596:BI350_RS01640
uniprot id: A0A1D8JCK7
names: Similarity
messages: Belongs to the peptidase U62 family.

298596:BI350 RS09050
gene id: 298596:BI350_RS09050
uniprot id: A0A1D8JG47
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

298596:BI350 RS16320
gene id: 298596:BI350_RS16320
uniprot id: A0A1D8JJS0
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

298596:BI350 RS06865
gene id: 298596:BI350_RS06865
uniprot id: A0A1D8JF00
names: Similarity
messages: Belongs to the GerABKA family.

298596:BI350 RS16275
gene id: 298596:BI350_RS16275
uniprot id: A0A1D8JJR7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

298596:BI350 RS15975
gene id: 298596:BI350_RS15975
uniprot id: A0A1D8JJL8
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

298596:BI350 RS12525
gene id: 298596:BI350_RS12525
uniprot id: A0A1D8JHX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

298596:BI350 RS09170
gene id: 298596:BI350_RS09170
uniprot id: A0A1D8JG50
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

298596:BI350 RS05590
gene id: 298596:BI350_RS05590
uniprot id: A0A1D8JED9
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

298596:BI350 RS02225
gene id: 298596:BI350_RS02225
uniprot id: A0A1D8JCW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

298596:BI350 RS11305
gene id: 298596:BI350_RS11305
uniprot id: A0A1D8JHA1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS00870
gene id: 298596:BI350_RS00870
uniprot id: A0A1D8JC86
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS13475
gene id: 298596:BI350_RS13475
uniprot id: A0A1D8JIA5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

298596:BI350 RS03970
gene id: 298596:BI350_RS03970
uniprot id: A0A1D8JDM6
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

298596:BI350 RS09820
gene id: 298596:BI350_RS09820
uniprot id: A0A1D8JGF3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

298596:BI350 RS07010
gene id: 298596:BI350_RS07010
uniprot id: A0A1D8JF35
names: Similarity
messages: Belongs to the RutC family.

298596:BI350 RS03995
gene id: 298596:BI350_RS03995
uniprot id: A0A1D8JDN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS12495
gene id: 298596:BI350_RS12495
uniprot id: A0A1D8JHS5
names: Subcellular Location Annotation
messages: Cytoplasm

298596:BI350 RS00510
gene id: 298596:BI350_RS00510
uniprot id: A0A1D8JC28
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS11965
gene id: 298596:BI350_RS11965
uniprot id: A0A1D8JHL1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

298596:BI350 RS16315
gene id: 298596:BI350_RS16315
uniprot id: A0A1D8JJR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

298596:BI350 RS12070
gene id: 298596:BI350_RS12070
uniprot id: A0A1D8JHK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

298596:BI350 RS08420
gene id: 298596:BI350_RS08420
uniprot id: A0A1D8JFT6
names: Similarity
messages: Belongs to the acyltransferase 3 family.

298596:BI350 RS01135
gene id: 298596:BI350_RS01135
uniprot id: A0A1D8JJX9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

298596:BI350 RS02555
gene id: 298596:BI350_RS02555
uniprot id: A0A1D8JD15
names: Similarity
messages: Belongs to the UPF0111 family.

298596:BI350 RS00380
gene id: 298596:BI350_RS00380
uniprot id: A0A1D8JC14
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS12800
gene id: 298596:BI350_RS12800
uniprot id: A0A1D8JI18
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

298596:BI350 RS05815
gene id: 298596:BI350_RS05815
uniprot id: A0A1D8JEH0
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

298596:BI350 RS10330
gene id: 298596:BI350_RS10330
uniprot id: A0A1D8JGP8
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS12850
gene id: 298596:BI350_RS12850
uniprot id: A0A1D8JI29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

298596:BI350 RS03020
gene id: 298596:BI350_RS03020
uniprot id: A0A1D8JK11
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

298596:BI350 RS06605
gene id: 298596:BI350_RS06605
uniprot id: A0A1D8JEV5
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

298596:BI350 RS12770
gene id: 298596:BI350_RS12770
uniprot id: A0A1D8JHY5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS01995
gene id: 298596:BI350_RS01995
uniprot id: A0A1D8JCS1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

298596:BI350 RS12785
gene id: 298596:BI350_RS12785
uniprot id: A0A1D8JHY4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

298596:BI350 RS01065
gene id: 298596:BI350_RS01065
uniprot id: A0A1D8JCB3
names: Similarity
messages: Belongs to the DCK/DGK family.

298596:BI350 RS06490
gene id: 298596:BI350_RS06490
uniprot id: A0A1D8JEU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

298596:BI350 RS02785
gene id: 298596:BI350_RS02785
uniprot id: A0A1D8JD57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

298596:BI350 RS08930
gene id: 298596:BI350_RS08930
uniprot id: A0A1D8JG03
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

298596:BI350 RS03400
gene id: 298596:BI350_RS03400
uniprot id: A0A1D8JDE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

298596:BI350 RS14555
gene id: 298596:BI350_RS14555
uniprot id: A0A1D8JIV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS12315
gene id: 298596:BI350_RS12315
uniprot id: A0A1D8JHR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

298596:BI350 RS13875
gene id: 298596:BI350_RS13875
uniprot id: A0A1D8JIJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

298596:BI350 RS00730
gene id: 298596:BI350_RS00730
uniprot id: A0A1D8JC56
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

298596:BI350 RS10435
gene id: 298596:BI350_RS10435
uniprot id: A0A1D8JGU4
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

298596:BI350 RS05780
gene id: 298596:BI350_RS05780
uniprot id: A0A1D8JEG5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS08270
gene id: 298596:BI350_RS08270
uniprot id: A0A1D8JFS3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

298596:BI350 RS12580
gene id: 298596:BI350_RS12580
uniprot id: A0A1D8JHY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

298596:BI350 RS12730
gene id: 298596:BI350_RS12730
uniprot id: A0A1D8JHW1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

298596:BI350 RS12005
gene id: 298596:BI350_RS12005
uniprot id: A0A1D8JHM0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

298596:BI350 RS09705
gene id: 298596:BI350_RS09705
uniprot id: A0A1D8JGC5
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

298596:BI350 RS04105
gene id: 298596:BI350_RS04105
uniprot id: A0A1D8JDT4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

298596:BI350 RS03660
gene id: 298596:BI350_RS03660
uniprot id: A0A1D8JDH8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.

298596:BI350 RS14990
gene id: 298596:BI350_RS14990
uniprot id: A0A1D8JJ35
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

298596:BI350 RS14215
gene id: 298596:BI350_RS14215
uniprot id: A0A1D8JIN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS11370
gene id: 298596:BI350_RS11370
uniprot id: A0A1D8JH85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

298596:BI350 RS16375
gene id: 298596:BI350_RS16375
uniprot id: A0A1D8JKS4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

298596:BI350 RS10220
gene id: 298596:BI350_RS10220
uniprot id: A0A1D8JGM7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

298596:BI350 RS13950
gene id: 298596:BI350_RS13950
uniprot id: A0A1D8JII9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS03685
gene id: 298596:BI350_RS03685
uniprot id: A0A1D8JDH5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

298596:BI350 RS01170
gene id: 298596:BI350_RS01170
uniprot id: A0A1D8JCB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

298596:BI350 RS06630
gene id: 298596:BI350_RS06630
uniprot id: A0A1D8JEW1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

298596:BI350 RS12880
gene id: 298596:BI350_RS12880
uniprot id: A0A1D8JI02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

298596:BI350 RS02195
gene id: 298596:BI350_RS02195
uniprot id: A0A1D8JCU9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

298596:BI350 RS04485
gene id: 298596:BI350_RS04485
uniprot id: A0A1D8JK43
names: Caution
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS15830
gene id: 298596:BI350_RS15830
uniprot id: A0A1D8JJK1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

298596:BI350 RS12890
gene id: 298596:BI350_RS12890
uniprot id: A0A1D8JI00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

298596:BI350 RS06430
gene id: 298596:BI350_RS06430
uniprot id: A0A1D8JES0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

298596:BI350 RS04350
gene id: 298596:BI350_RS04350
uniprot id: A0A1D8JDV6
names: Similarity
messages: Belongs to the UPF0342 family.

298596:BI350 RS13980
gene id: 298596:BI350_RS13980
uniprot id: A0A1D8JKM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

298596:BI350 RS04945
gene id: 298596:BI350_RS04945
uniprot id: A0A1D8JE43
names: Similarity
messages: Belongs to the HepT RNase toxin family.

298596:BI350 RS05485
gene id: 298596:BI350_RS05485
uniprot id: A0A1D8JEB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS00240
gene id: 298596:BI350_RS00240
uniprot id: A0A1D8JJZ3
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

298596:BI350 RS11190
gene id: 298596:BI350_RS11190
uniprot id: A0A1D8JKG7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

298596:BI350 RS05035
gene id: 298596:BI350_RS05035
uniprot id: A0A1D8JE78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

298596:BI350 RS02700
gene id: 298596:BI350_RS02700
uniprot id: A0A1D8JD45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS06660
gene id: 298596:BI350_RS06660
uniprot id: A0A1D8JEW4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

298596:BI350 RS02250
gene id: 298596:BI350_RS02250
uniprot id: A0A1D8JCW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

298596:BI350 RS09805
gene id: 298596:BI350_RS09805
uniprot id: A0A1D8JGE3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

298596:BI350 RS15330
gene id: 298596:BI350_RS15330
uniprot id: A0A1D8JJB4
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

298596:BI350 RS07830
gene id: 298596:BI350_RS07830
uniprot id: A0A1D8JFG3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS10045
gene id: 298596:BI350_RS10045
uniprot id: A0A1D8JGJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

298596:BI350 RS05045
gene id: 298596:BI350_RS05045
uniprot id: A0A1D8JE70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS06780
gene id: 298596:BI350_RS06780
uniprot id: A0A1D8JF04
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

298596:BI350 RS04675
gene id: 298596:BI350_RS04675
uniprot id: A0A1D8JE07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

298596:BI350 RS12215
gene id: 298596:BI350_RS12215
uniprot id: A0A1D8JHM2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

298596:BI350 RS07040
gene id: 298596:BI350_RS07040
uniprot id: A0A1D8JF37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

298596:BI350 RS11770
gene id: 298596:BI350_RS11770
uniprot id: A0A1D8JHF4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

298596:BI350 RS12780
gene id: 298596:BI350_RS12780
uniprot id: A0A1D8JHX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

298596:BI350 RS03795
gene id: 298596:BI350_RS03795
uniprot id: A0A1D8JDM3
names: Subcellular Location Annotation
messages: Cytoplasm

298596:BI350 RS01355
gene id: 298596:BI350_RS01355
uniprot id: A0A1D8JCE9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS11985
gene id: 298596:BI350_RS11985
uniprot id: A0A1D8JHJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

298596:BI350 RS04330
gene id: 298596:BI350_RS04330
uniprot id: A0A1D8JDT1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS13085
gene id: 298596:BI350_RS13085
uniprot id: A0A1D8JI37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS12680
gene id: 298596:BI350_RS12680
uniprot id: A0A1D8JHV8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

298596:BI350 RS07055
gene id: 298596:BI350_RS07055
uniprot id: A0A1D8JF32
names: Similarity
messages: Belongs to the EamA transporter family.

298596:BI350 RS01500
gene id: 298596:BI350_RS01500
uniprot id: A0A1D8JCH9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS12245
gene id: 298596:BI350_RS12245
uniprot id: A0A1D8JHQ9
names: Similarity
messages: Belongs to the peptidase M16 family.

298596:BI350 RS01270
gene id: 298596:BI350_RS01270
uniprot id: A0A1D8JCD8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

298596:BI350 RS09755
gene id: 298596:BI350_RS09755
uniprot id: A0A1D8JGD3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

298596:BI350 RS01730
gene id: 298596:BI350_RS01730
uniprot id: A0A1D8JCM0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

298596:BI350 RS00770
gene id: 298596:BI350_RS00770
uniprot id: A0A1D8JC57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

298596:BI350 RS00905
gene id: 298596:BI350_RS00905
uniprot id: A0A1D8JC81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

298596:BI350 RS07495
gene id: 298596:BI350_RS07495
uniprot id: A0A1D8JFE0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS02550
gene id: 298596:BI350_RS02550
uniprot id: A0A1D8JD13
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS05025
gene id: 298596:BI350_RS05025
uniprot id: A0A1D8JE54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS06300
gene id: 298596:BI350_RS06300
uniprot id: A0A1D8JER4
names: Function
names: Similarity
names: Subunit
messages: Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

298596:BI350 RS12565
gene id: 298596:BI350_RS12565
uniprot id: A0A1D8JHT7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

298596:BI350 RS14610
gene id: 298596:BI350_RS14610
uniprot id: A0A1D8JIW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS15535
gene id: 298596:BI350_RS15535
uniprot id: A0A1D8JJD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

298596:BI350 RS14795
gene id: 298596:BI350_RS14795
uniprot id: A0A1D8JJ17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

298596:BI350 RS15880
gene id: 298596:BI350_RS15880
uniprot id: A0A1D8JJJ3
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

298596:BI350 RS13480
gene id: 298596:BI350_RS13480
uniprot id: A0A1D8JID3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS02000
gene id: 298596:BI350_RS02000
uniprot id: A0A1D8JCR8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

298596:BI350 RS02220
gene id: 298596:BI350_RS02220
uniprot id: A0A1D8JCV6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

298596:BI350 RS12740
gene id: 298596:BI350_RS12740
uniprot id: A0A1D8JHW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

298596:BI350 RS03940
gene id: 298596:BI350_RS03940
uniprot id: A0A1D8JDP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

298596:BI350 RS10285
gene id: 298596:BI350_RS10285
uniprot id: A0A1D8JGR9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

298596:BI350 RS15225
gene id: 298596:BI350_RS15225
uniprot id: A0A1D8JJ97
names: Similarity
messages: Belongs to the acyltransferase 3 family.

298596:BI350 RS08165
gene id: 298596:BI350_RS08165
uniprot id: A0A1D8JFN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

298596:BI350 RS02955
gene id: 298596:BI350_RS02955
uniprot id: A0A1D8JD93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

298596:BI350 RS01920
gene id: 298596:BI350_RS01920
uniprot id: A0A1D8JCQ1
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS07090
gene id: 298596:BI350_RS07090
uniprot id: A0A1D8JF47
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

298596:BI350 RS06270
gene id: 298596:BI350_RS06270
uniprot id: A0A1D8JKA9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

298596:BI350 RS00855
gene id: 298596:BI350_RS00855
uniprot id: A0A1D8JC85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

298596:BI350 RS05385
gene id: 298596:BI350_RS05385
uniprot id: A0A1D8JK53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

298596:BI350 RS04020
gene id: 298596:BI350_RS04020
uniprot id: A0A1D8JDQ8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

298596:BI350 RS12625
gene id: 298596:BI350_RS12625
uniprot id: A0A1D8JHU9
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

298596:BI350 RS05340
gene id: 298596:BI350_RS05340
uniprot id: A0A1D8JE98
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

298596:BI350 RS00410
gene id: 298596:BI350_RS00410
uniprot id: A0A1D8JC13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

298596:BI350 RS03595
gene id: 298596:BI350_RS03595
uniprot id: A0A1D8JDG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

298596:BI350 RS15605
gene id: 298596:BI350_RS15605
uniprot id: A0A1D8JJG0
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS02025
gene id: 298596:BI350_RS02025
uniprot id: A0A1D8JCS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

298596:BI350 RS11255
gene id: 298596:BI350_RS11255
uniprot id: A0A1D8JH95
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS05770
gene id: 298596:BI350_RS05770
uniprot id: A0A1D8JEG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

298596:BI350 RS05840
gene id: 298596:BI350_RS05840
uniprot id: A0A1D8JEH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

298596:BI350 RS06500
gene id: 298596:BI350_RS06500
uniprot id: A0A1D8JET6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

298596:BI350 RS13275
gene id: 298596:BI350_RS13275
uniprot id: A0A1D8JI73
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS10740
gene id: 298596:BI350_RS10740
uniprot id: A0A1D8JKF6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

298596:BI350 RS10075
gene id: 298596:BI350_RS10075
uniprot id: A0A1D8JGK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ComGC family.
messages: Cell membrane
messages: Homodimer.
messages: Required for transformation and DNA binding.

298596:BI350 RS02715
gene id: 298596:BI350_RS02715
uniprot id: A0A1D8JD40
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

298596:BI350 RS01240
gene id: 298596:BI350_RS01240
uniprot id: A0A1D8JCD0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

298596:BI350 RS13210
gene id: 298596:BI350_RS13210
uniprot id: A0A1D8JI62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

298596:BI350 RS00630
gene id: 298596:BI350_RS00630
uniprot id: A0A1D8JC51
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS02375
gene id: 298596:BI350_RS02375
uniprot id: A0A1D8JCY5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

298596:BI350 RS12295
gene id: 298596:BI350_RS12295
uniprot id: A0A1D8JHP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

298596:BI350 RS05515
gene id: 298596:BI350_RS05515
uniprot id: A0A1D8JEC3
names: Cofactor
messages: Binds 1 FAD per subunit.

298596:BI350 RS08725
gene id: 298596:BI350_RS08725
uniprot id: A0A1D8JKG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

298596:BI350 RS00260
gene id: 298596:BI350_RS00260
uniprot id: A0A1D8JBY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family. IolA subfamily.
messages: Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.
messages: Homotetramer.

298596:BI350 RS02540
gene id: 298596:BI350_RS02540
uniprot id: A0A1D8JD12
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS15030
gene id: 298596:BI350_RS15030
uniprot id: A0A1D8JJ37
names: Similarity
messages: Belongs to the ABC transporter superfamily.

298596:BI350 RS11620
gene id: 298596:BI350_RS11620
uniprot id: A0A1D8JHC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS03100
gene id: 298596:BI350_RS03100
uniprot id: A0A1D8JD97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

298596:BI350 RS08535
gene id: 298596:BI350_RS08535
uniprot id: A0A1D8JFT3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

298596:BI350 RS12630
gene id: 298596:BI350_RS12630
uniprot id: A0A1D8JHX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

298596:BI350 RS02935
gene id: 298596:BI350_RS02935
uniprot id: A0A1D8JD85
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS00780
gene id: 298596:BI350_RS00780
uniprot id: A0A1D8JC58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.

298596:BI350 RS05315
gene id: 298596:BI350_RS05315
uniprot id: A0A1D8JE91
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

298596:BI350 RS04550
gene id: 298596:BI350_RS04550
uniprot id: A0A1D8JDW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

298596:BI350 RS00385
gene id: 298596:BI350_RS00385
uniprot id: A0A1D8JC10
names: Similarity
messages: Belongs to the EamA transporter family.

298596:BI350 RS07215
gene id: 298596:BI350_RS07215
uniprot id: A0A1D8JF91
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS06470
gene id: 298596:BI350_RS06470
uniprot id: A0A1D8JET8
names: Similarity
messages: Belongs to the peptidase S49 family.

298596:BI350 RS06665
gene id: 298596:BI350_RS06665
uniprot id: A0A1D8JEY7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

298596:BI350 RS15600
gene id: 298596:BI350_RS15600
uniprot id: A0A1D8JJE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

298596:BI350 RS03845
gene id: 298596:BI350_RS03845
uniprot id: A0A1D8JDN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

298596:BI350 RS10780
gene id: 298596:BI350_RS10780
uniprot id: A0A1D8JGX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS00130
gene id: 298596:BI350_RS00130
uniprot id: A0A1D8JBW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS14465
gene id: 298596:BI350_RS14465
uniprot id: A0A1D8JIT4
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

298596:BI350 RS14055
gene id: 298596:BI350_RS14055
uniprot id: A0A1D8JIK9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

298596:BI350 RS08655
gene id: 298596:BI350_RS08655
uniprot id: A0A1D8JFV7
names: Similarity
messages: Belongs to the GSP E family.

298596:BI350 RS00460
gene id: 298596:BI350_RS00460
uniprot id: A0A1D8JC26
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS04960
gene id: 298596:BI350_RS04960
uniprot id: A0A1D8JE71
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

298596:BI350 RS02845
gene id: 298596:BI350_RS02845
uniprot id: A0A1D8JD63
names: Similarity
messages: Belongs to the CvfB family.

298596:BI350 RS09235
gene id: 298596:BI350_RS09235
uniprot id: A0A1D8JG70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS01975
gene id: 298596:BI350_RS01975
uniprot id: A0A1D8JCR3
names: Similarity
messages: Belongs to the ycf81 family.

298596:BI350 RS07130
gene id: 298596:BI350_RS07130
uniprot id: A0A1D8JF55
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

298596:BI350 RS04920
gene id: 298596:BI350_RS04920
uniprot id: A0A1D8JE33
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS06985
gene id: 298596:BI350_RS06985
uniprot id: A0A1D8JF30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

298596:BI350 RS13595
gene id: 298596:BI350_RS13595
uniprot id: A0A1D8JIC4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

298596:BI350 RS11715
gene id: 298596:BI350_RS11715
uniprot id: A0A1D8JHE5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

298596:BI350 RS02200
gene id: 298596:BI350_RS02200
uniprot id: A0A1D8JCV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

298596:BI350 RS03425
gene id: 298596:BI350_RS03425
uniprot id: A0A1D8JDG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

298596:BI350 RS08140
gene id: 298596:BI350_RS08140
uniprot id: A0A1D8JFL9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

298596:BI350 RS09605
gene id: 298596:BI350_RS09605
uniprot id: A0A1D8JGC1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS11780
gene id: 298596:BI350_RS11780
uniprot id: A0A1D8JHG9
names: Subcellular Location Annotation
messages: Cytoplasm

298596:BI350 RS01715
gene id: 298596:BI350_RS01715
uniprot id: A0A1D8JCM7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

298596:BI350 RS07440
gene id: 298596:BI350_RS07440
uniprot id: A0A1D8JFD0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

298596:BI350 RS01505
gene id: 298596:BI350_RS01505
uniprot id: A0A1D8JCI7
names: Similarity
messages: Belongs to the TrpC family.

298596:BI350 RS12150
gene id: 298596:BI350_RS12150
uniprot id: A0A1D8JHL3
names: Similarity
messages: Belongs to the CinA family.

298596:BI350 RS16310
gene id: 298596:BI350_RS16310
uniprot id: A0A1D8JJR5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

298596:BI350 RS15240
gene id: 298596:BI350_RS15240
uniprot id: A0A1D8JJ78
names: Similarity
messages: Belongs to the peptidase S8 family.

298596:BI350 RS06860
gene id: 298596:BI350_RS06860
uniprot id: A0A1D8JF09
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

298596:BI350 RS06935
gene id: 298596:BI350_RS06935
uniprot id: A0A1D8JF33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

298596:BI350 RS09355
gene id: 298596:BI350_RS09355
uniprot id: A0A1D8JG91
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS16035
gene id: 298596:BI350_RS16035
uniprot id: A0A1D8JJP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

298596:BI350 RS13365
gene id: 298596:BI350_RS13365
uniprot id: A0A1D8JIB7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

298596:BI350 RS11290
gene id: 298596:BI350_RS11290
uniprot id: A0A1D8JH84
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

298596:BI350 RS06530
gene id: 298596:BI350_RS06530
uniprot id: A0A1D8JEU6
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.

298596:BI350 RS10560
gene id: 298596:BI350_RS10560
uniprot id: A0A1D8JGX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

298596:BI350 RS13165
gene id: 298596:BI350_RS13165
uniprot id: A0A1D8JI54
names: Similarity
messages: Belongs to the UPF0637 family.

298596:BI350 RS00865
gene id: 298596:BI350_RS00865
uniprot id: A0A1D8JC79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

298596:BI350 RS06990
gene id: 298596:BI350_RS06990
uniprot id: A0A1D8JF23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

298596:BI350 RS02685
gene id: 298596:BI350_RS02685
uniprot id: A0A1D8JD41
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS06850
gene id: 298596:BI350_RS06850
uniprot id: A0A1D8JF01
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

298596:BI350 RS00520
gene id: 298596:BI350_RS00520
uniprot id: A0A1D8JC43
names: Similarity
messages: Belongs to the type IA topoisomerase family.

298596:BI350 RS02125
gene id: 298596:BI350_RS02125
uniprot id: A0A1D8JCU0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

298596:BI350 RS15795
gene id: 298596:BI350_RS15795
uniprot id: A0A1D8JJH7
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS02040
gene id: 298596:BI350_RS02040
uniprot id: A0A1D8JCS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

298596:BI350 RS09220
gene id: 298596:BI350_RS09220
uniprot id: A0A1D8JG77
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

298596:BI350 RS01705
gene id: 298596:BI350_RS01705
uniprot id: A0A1D8JCK5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS04835
gene id: 298596:BI350_RS04835
uniprot id: A0A1D8JE22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

298596:BI350 RS08550
gene id: 298596:BI350_RS08550
uniprot id: A0A1D8JKC8
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS06025
gene id: 298596:BI350_RS06025
uniprot id: A0A1D8JEK5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

298596:BI350 RS13360
gene id: 298596:BI350_RS13360
uniprot id: A0A1D8JIB1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

298596:BI350 RS12420
gene id: 298596:BI350_RS12420
uniprot id: A0A1D8JHT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

298596:BI350 RS06420
gene id: 298596:BI350_RS06420
uniprot id: A0A1D8JES4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

298596:BI350 RS10205
gene id: 298596:BI350_RS10205
uniprot id: A0A1D8JKE8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

298596:BI350 RS01150
gene id: 298596:BI350_RS01150
uniprot id: A0A1D8JCC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

298596:BI350 RS01245
gene id: 298596:BI350_RS01245
uniprot id: A0A1D8JCD6
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

298596:BI350 RS06620
gene id: 298596:BI350_RS06620
uniprot id: A0A1D8JEV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

298596:BI350 RS01165
gene id: 298596:BI350_RS01165
uniprot id: A0A1D8JCC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

298596:BI350 RS01965
gene id: 298596:BI350_RS01965
uniprot id: A0A1D8JCR0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

298596:BI350 RS11350
gene id: 298596:BI350_RS11350
uniprot id: A0A1D8JHB2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

298596:BI350 RS12610
gene id: 298596:BI350_RS12610
uniprot id: A0A1D8JHV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

298596:BI350 RS06870
gene id: 298596:BI350_RS06870
uniprot id: A0A1D8JF11
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

298596:BI350 RS03985
gene id: 298596:BI350_RS03985
uniprot id: A0A1D8JDR6
names: Similarity
messages: Belongs to the MotB family.

298596:BI350 RS07460
gene id: 298596:BI350_RS07460
uniprot id: A0A1D8JFA2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

298596:BI350 RS13675
gene id: 298596:BI350_RS13675
uniprot id: A0A1D8JID6
names: Similarity
messages: Belongs to the peptidase S41A family.

298596:BI350 RS12595
gene id: 298596:BI350_RS12595
uniprot id: A0A1D8JHU8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

298596:BI350 RS12440
gene id: 298596:BI350_RS12440
uniprot id: A0A1D8JKJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

298596:BI350 RS12280
gene id: 298596:BI350_RS12280
uniprot id: A0A1D8JHP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

298596:BI350 RS04735
gene id: 298596:BI350_RS04735
uniprot id: A0A1D8JE29
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS02815
gene id: 298596:BI350_RS02815
uniprot id: A0A1D8JK27
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

298596:BI350 RS13125
gene id: 298596:BI350_RS13125
uniprot id: A0A1D8JI80
names: Similarity
messages: Belongs to the UPF0358 family.

298596:BI350 RS00890
gene id: 298596:BI350_RS00890
uniprot id: A0A1D8JC78
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

298596:BI350 RS14970
gene id: 298596:BI350_RS14970
uniprot id: A0A1D8JJ32
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS08120
gene id: 298596:BI350_RS08120
uniprot id: A0A1D8JFL3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS06610
gene id: 298596:BI350_RS06610
uniprot id: A0A1D8JEX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

298596:BI350 RS10600
gene id: 298596:BI350_RS10600
uniprot id: A0A1D8JGW6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

298596:BI350 RS08495
gene id: 298596:BI350_RS08495
uniprot id: A0A1D8JFW5
names: Similarity
messages: Belongs to the universal stress protein A family.

298596:BI350 RS07625
gene id: 298596:BI350_RS07625
uniprot id: A0A1D8JFD6
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS04755
gene id: 298596:BI350_RS04755
uniprot id: A0A1D8JE08
names: Subcellular Location Annotation
messages: cell wall

298596:BI350 RS16400
gene id: 298596:BI350_RS16400
uniprot id: A0A1D8JKS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS01220
gene id: 298596:BI350_RS01220
uniprot id: A0A1D8JCD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

298596:BI350 RS03960
gene id: 298596:BI350_RS03960
uniprot id: A0A1D8JDQ6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

298596:BI350 RS13990
gene id: 298596:BI350_RS13990
uniprot id: A0A1D8JIK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS02720
gene id: 298596:BI350_RS02720
uniprot id: A0A1D8JD47
names: Similarity
messages: Belongs to the peptidase C56 family.

298596:BI350 RS08800
gene id: 298596:BI350_RS08800
uniprot id: A0A1D8JFY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

298596:BI350 RS04670
gene id: 298596:BI350_RS04670
uniprot id: A0A1D8JDZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

298596:BI350 RS06125
gene id: 298596:BI350_RS06125
uniprot id: A0A1D8JEL1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

298596:BI350 RS15590
gene id: 298596:BI350_RS15590
uniprot id: A0A1D8JKP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

298596:BI350 RS15275
gene id: 298596:BI350_RS15275
uniprot id: A0A1D8JJA6
names: Similarity
messages: Belongs to the peptidase S8 family.

298596:BI350 RS11470
gene id: 298596:BI350_RS11470
uniprot id: A0A1D8JHA3
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS03505
gene id: 298596:BI350_RS03505
uniprot id: A0A1D8JK66
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

298596:BI350 RS08310
gene id: 298596:BI350_RS08310
uniprot id: A0A1D8JFQ2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

298596:BI350 RS14165
gene id: 298596:BI350_RS14165
uniprot id: A0A1D8JIP1
names: Similarity
messages: Belongs to the proline racemase family.

298596:BI350 RS05505
gene id: 298596:BI350_RS05505
uniprot id: A0A1D8JEA9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

298596:BI350 RS12820
gene id: 298596:BI350_RS12820
uniprot id: A0A1D8JHZ3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

298596:BI350 RS14700
gene id: 298596:BI350_RS14700
uniprot id: A0A1D8JIX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

298596:BI350 RS09360
gene id: 298596:BI350_RS09360
uniprot id: A0A1D8JG65
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS15645
gene id: 298596:BI350_RS15645
uniprot id: A0A1D8JJG4
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

298596:BI350 RS05470
gene id: 298596:BI350_RS05470
uniprot id: A0A1D8JEB9
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS01545
gene id: 298596:BI350_RS01545
uniprot id: A0A1D8JCJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS06265
gene id: 298596:BI350_RS06265
uniprot id: A0A1D8JER7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

298596:BI350 RS15575
gene id: 298596:BI350_RS15575
uniprot id: A0A1D8JJE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

298596:BI350 RS10995
gene id: 298596:BI350_RS10995
uniprot id: A0A1D8JH32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

298596:BI350 RS10340
gene id: 298596:BI350_RS10340
uniprot id: A0A1D8JGT2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

298596:BI350 RS12265
gene id: 298596:BI350_RS12265
uniprot id: A0A1D8JHN2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

298596:BI350 RS09620
gene id: 298596:BI350_RS09620
uniprot id: A0A1D8JGE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

298596:BI350 RS12110
gene id: 298596:BI350_RS12110
uniprot id: A0A1D8JHK6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

298596:BI350 RS11325
gene id: 298596:BI350_RS11325
uniprot id: A0A1D8JH98
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

298596:BI350 RS15950
gene id: 298596:BI350_RS15950
uniprot id: A0A1D8JJL9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

298596:BI350 RS05685
gene id: 298596:BI350_RS05685
uniprot id: A0A1D8JEG0
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

298596:BI350 RS02895
gene id: 298596:BI350_RS02895
uniprot id: A0A1D8JD66
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS13935
gene id: 298596:BI350_RS13935
uniprot id: A0A1D8JIJ0
names: Similarity
messages: Belongs to the peptidase S9C family.

298596:BI350 RS14035
gene id: 298596:BI350_RS14035
uniprot id: A0A1D8JIL3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

298596:BI350 RS11455
gene id: 298596:BI350_RS11455
uniprot id: A0A1D8JH97
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

298596:BI350 RS04275
gene id: 298596:BI350_RS04275
uniprot id: A0A1D8JK49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

298596:BI350 RS11160
gene id: 298596:BI350_RS11160
uniprot id: A0A1D8JH50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

298596:BI350 RS14400
gene id: 298596:BI350_RS14400
uniprot id: A0A1D8JIT1
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS02210
gene id: 298596:BI350_RS02210
uniprot id: A0A1D8JCV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

298596:BI350 RS04315
gene id: 298596:BI350_RS04315
uniprot id: A0A1D8JDS7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS05510
gene id: 298596:BI350_RS05510
uniprot id: A0A1D8JEB5
names: Similarity
messages: Belongs to the UPF0178 family.

298596:BI350 RS09790
gene id: 298596:BI350_RS09790
uniprot id: A0A1D8JGH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

298596:BI350 RS16295
gene id: 298596:BI350_RS16295
uniprot id: A0A1D8JJR6
names: Similarity
messages: Belongs to the MoaD family.

298596:BI350 RS03930
gene id: 298596:BI350_RS03930
uniprot id: A0A1D8JK41
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

298596:BI350 RS02365
gene id: 298596:BI350_RS02365
uniprot id: A0A1D8JCY3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

298596:BI350 RS12390
gene id: 298596:BI350_RS12390
uniprot id: A0A1D8JKJ1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

298596:BI350 RS11500
gene id: 298596:BI350_RS11500
uniprot id: A0A1D8JHA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

298596:BI350 RS02615
gene id: 298596:BI350_RS02615
uniprot id: A0A1D8JD26
names: Function
names: Similarity
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

298596:BI350 RS10035
gene id: 298596:BI350_RS10035
uniprot id: A0A1D8JGL8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS09610
gene id: 298596:BI350_RS09610
uniprot id: A0A1D8JGD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

298596:BI350 RS04855
gene id: 298596:BI350_RS04855
uniprot id: A0A1D8JE50
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

298596:BI350 RS06450
gene id: 298596:BI350_RS06450
uniprot id: A0A1D8JES1
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

298596:BI350 RS12300
gene id: 298596:BI350_RS12300
uniprot id: A0A1D8JHR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

298596:BI350 RS01470
gene id: 298596:BI350_RS01470
uniprot id: A0A1D8JCH7
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

298596:BI350 RS11105
gene id: 298596:BI350_RS11105
uniprot id: A0A1D8JH39
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS13535
gene id: 298596:BI350_RS13535
uniprot id: A0A1D8JIB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

298596:BI350 RS01745
gene id: 298596:BI350_RS01745
uniprot id: A0A1D8JCL9
names: Similarity
messages: Belongs to the EamA transporter family.

298596:BI350 RS08500
gene id: 298596:BI350_RS08500
uniprot id: A0A1D8JFT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS08170
gene id: 298596:BI350_RS08170
uniprot id: A0A1D8JFM3
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

298596:BI350 RS00140
gene id: 298596:BI350_RS00140
uniprot id: A0A1D8JJV9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

298596:BI350 RS09830
gene id: 298596:BI350_RS09830
uniprot id: A0A1D8JGJ2
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

298596:BI350 RS11490
gene id: 298596:BI350_RS11490
uniprot id: A0A1D8JHB3
names: Similarity
messages: Belongs to the peptidase S11 family.

298596:BI350 RS08150
gene id: 298596:BI350_RS08150
uniprot id: A0A1D8JFM1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

298596:BI350 RS07030
gene id: 298596:BI350_RS07030
uniprot id: A0A1D8JF58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

298596:BI350 RS05330
gene id: 298596:BI350_RS05330
uniprot id: A0A1D8JEB0
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

298596:BI350 RS10005
gene id: 298596:BI350_RS10005
uniprot id: A0A1D8JGL2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the octanoyltransferase LipM family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation.
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. The reaction proceeds via an octanoyl-thioester enzyme intermediate.
messages: Monomer.

298596:BI350 RS15040
gene id: 298596:BI350_RS15040
uniprot id: A0A1D8JJ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS15690
gene id: 298596:BI350_RS15690
uniprot id: A0A1D8JJF5
names: Similarity
messages: Belongs to the FBPase class 2 family.

298596:BI350 RS02095
gene id: 298596:BI350_RS02095
uniprot id: A0A1D8JCT6
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS14105
gene id: 298596:BI350_RS14105
uniprot id: A0A1D8JIN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

298596:BI350 RS03480
gene id: 298596:BI350_RS03480
uniprot id: A0A1D8JDH7
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

298596:BI350 RS06345
gene id: 298596:BI350_RS06345
uniprot id: A0A1D8JER1
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

298596:BI350 RS09885
gene id: 298596:BI350_RS09885
uniprot id: A0A1D8JGJ5
names: Similarity
messages: Belongs to the TlyA family.

298596:BI350 RS03115
gene id: 298596:BI350_RS03115
uniprot id: A0A1D8JDA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

298596:BI350 RS06770
gene id: 298596:BI350_RS06770
uniprot id: A0A1D8JEZ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS07080
gene id: 298596:BI350_RS07080
uniprot id: A0A1D8JF41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

298596:BI350 RS11995
gene id: 298596:BI350_RS11995
uniprot id: A0A1D8JHI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS15415
gene id: 298596:BI350_RS15415
uniprot id: A0A1D8JJB2
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

298596:BI350 RS09615
gene id: 298596:BI350_RS09615
uniprot id: A0A1D8JGB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

298596:BI350 RS16355
gene id: 298596:BI350_RS16355
uniprot id: A0A1D8JJS9
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS08790
gene id: 298596:BI350_RS08790
uniprot id: A0A1D8JFX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

298596:BI350 RS05080
gene id: 298596:BI350_RS05080
uniprot id: A0A1D8JE65
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

298596:BI350 RS07435
gene id: 298596:BI350_RS07435
uniprot id: A0A1D8JF99
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS00275
gene id: 298596:BI350_RS00275
uniprot id: A0A1D8JBZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

298596:BI350 RS01940
gene id: 298596:BI350_RS01940
uniprot id: A0A1D8JCP8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

298596:BI350 RS06160
gene id: 298596:BI350_RS06160
uniprot id: A0A1D8JEL3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

298596:BI350 RS08395
gene id: 298596:BI350_RS08395
uniprot id: A0A1D8JFU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

298596:BI350 RS00395
gene id: 298596:BI350_RS00395
uniprot id: A0A1D8JC12
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

298596:BI350 RS01840
gene id: 298596:BI350_RS01840
uniprot id: A0A1D8JCP7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

298596:BI350 RS12615
gene id: 298596:BI350_RS12615
uniprot id: A0A1D8JHU6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

298596:BI350 RS11875
gene id: 298596:BI350_RS11875
uniprot id: A0A1D8JHI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

298596:BI350 RS04750
gene id: 298596:BI350_RS04750
uniprot id: A0A1D8JE02
names: Subcellular Location Annotation
messages: cell wall

298596:BI350 RS03835
gene id: 298596:BI350_RS03835
uniprot id: A0A1D8JK76
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

298596:BI350 RS01040
gene id: 298596:BI350_RS01040
uniprot id: A0A1D8JCB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

298596:BI350 RS04640
gene id: 298596:BI350_RS04640
uniprot id: A0A1D8JDZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

298596:BI350 RS15720
gene id: 298596:BI350_RS15720
uniprot id: A0A1D8JJH4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS13035
gene id: 298596:BI350_RS13035
uniprot id: A0A1D8JI32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0298 family.
messages: Cytoplasm

298596:BI350 RS01880
gene id: 298596:BI350_RS01880
uniprot id: A0A1D8JCN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

298596:BI350 RS01015
gene id: 298596:BI350_RS01015
uniprot id: A0A1D8JC97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

298596:BI350 RS07135
gene id: 298596:BI350_RS07135
uniprot id: A0A1D8JKD5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

298596:BI350 RS04250
gene id: 298596:BI350_RS04250
uniprot id: A0A1D8JDQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

298596:BI350 RS08115
gene id: 298596:BI350_RS08115
uniprot id: A0A1D8JFL8
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

298596:BI350 RS00860
gene id: 298596:BI350_RS00860
uniprot id: A0A1D8JC77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

298596:BI350 RS02020
gene id: 298596:BI350_RS02020
uniprot id: A0A1D8JJZ5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

298596:BI350 RS01265
gene id: 298596:BI350_RS01265
uniprot id: A0A1D8JCD5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

298596:BI350 RS05310
gene id: 298596:BI350_RS05310
uniprot id: A0A1D8JE85
names: Similarity
messages: Belongs to the isochorismate synthase family.

298596:BI350 RS04725
gene id: 298596:BI350_RS04725
uniprot id: A0A1D8JE17
names: Similarity
messages: Belongs to the ABC transporter superfamily.

298596:BI350 RS08805
gene id: 298596:BI350_RS08805
uniprot id: A0A1D8JG02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

298596:BI350 RS06960
gene id: 298596:BI350_RS06960
uniprot id: A0A1D8JF16
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

298596:BI350 RS15665
gene id: 298596:BI350_RS15665
uniprot id: A0A1D8JJF7
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

298596:BI350 RS11475
gene id: 298596:BI350_RS11475
uniprot id: A0A1D8JHB4
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS03980
gene id: 298596:BI350_RS03980
uniprot id: A0A1D8JDN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

298596:BI350 RS06365
gene id: 298596:BI350_RS06365
uniprot id: A0A1D8JER9
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

298596:BI350 RS10140
gene id: 298596:BI350_RS10140
uniprot id: A0A1D8JGL9
names: Similarity
messages: Belongs to the transpeptidase family.

298596:BI350 RS06645
gene id: 298596:BI350_RS06645
uniprot id: A0A1D8JEW5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS11785
gene id: 298596:BI350_RS11785
uniprot id: A0A1D8JHF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.

298596:BI350 RS04615
gene id: 298596:BI350_RS04615
uniprot id: A0A1D8JDY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

298596:BI350 RS01540
gene id: 298596:BI350_RS01540
uniprot id: A0A1D8JCI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS15800
gene id: 298596:BI350_RS15800
uniprot id: A0A1D8JJH3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

298596:BI350 RS02205
gene id: 298596:BI350_RS02205
uniprot id: A0A1D8JCV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

298596:BI350 RS00720
gene id: 298596:BI350_RS00720
uniprot id: A0A1D8JC49
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

298596:BI350 RS11865
gene id: 298596:BI350_RS11865
uniprot id: A0A1D8JHH4
names: Similarity
messages: Belongs to the EamA transporter family.

298596:BI350 RS13250
gene id: 298596:BI350_RS13250
uniprot id: A0A1D8JI94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS12775
gene id: 298596:BI350_RS12775
uniprot id: A0A1D8JHY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

298596:BI350 RS09895
gene id: 298596:BI350_RS09895
uniprot id: A0A1D8JGG8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

298596:BI350 RS16245
gene id: 298596:BI350_RS16245
uniprot id: A0A1D8JKP8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

298596:BI350 RS12905
gene id: 298596:BI350_RS12905
uniprot id: A0A1D8JI38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

298596:BI350 RS03695
gene id: 298596:BI350_RS03695
uniprot id: A0A1D8JDJ7
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

298596:BI350 RS03135
gene id: 298596:BI350_RS03135
uniprot id: A0A1D8JDB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

298596:BI350 RS11345
gene id: 298596:BI350_RS11345
uniprot id: A0A1D8JH76
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

298596:BI350 RS15180
gene id: 298596:BI350_RS15180
uniprot id: A0A1D8JJ70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LytR/CpsA/Psr (LCP) family.
messages: Cell membrane
messages: May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG).

298596:BI350 RS04050
gene id: 298596:BI350_RS04050
uniprot id: A0A1D8JDQ3
names: Similarity
messages: Belongs to the gamma-type SASP family.

298596:BI350 RS04040
gene id: 298596:BI350_RS04040
uniprot id: A0A1D8JDN9
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

298596:BI350 RS07775
gene id: 298596:BI350_RS07775
uniprot id: A0A1D8JFF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

298596:BI350 RS04850
gene id: 298596:BI350_RS04850
uniprot id: A0A1D8JE25
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

298596:BI350 RS00610
gene id: 298596:BI350_RS00610
uniprot id: A0A1D8JC52
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS04705
gene id: 298596:BI350_RS04705
uniprot id: A0A1D8JDZ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

298596:BI350 RS02730
gene id: 298596:BI350_RS02730
uniprot id: A0A1D8JD44
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS15515
gene id: 298596:BI350_RS15515
uniprot id: A0A1D8JJD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

298596:BI350 RS08825
gene id: 298596:BI350_RS08825
uniprot id: A0A1D8JFY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS11295
gene id: 298596:BI350_RS11295
uniprot id: A0A1D8JH66
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

298596:BI350 RS09875
gene id: 298596:BI350_RS09875
uniprot id: A0A1D8JGI8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

298596:BI350 RS09640
gene id: 298596:BI350_RS09640
uniprot id: A0A1D8JGD6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Monomer.

298596:BI350 RS11185
gene id: 298596:BI350_RS11185
uniprot id: A0A1D8JH79
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

298596:BI350 RS09315
gene id: 298596:BI350_RS09315
uniprot id: A0A1D8JG74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

298596:BI350 RS01565
gene id: 298596:BI350_RS01565
uniprot id: A0A1D8JK26
names: Similarity
messages: Belongs to the ABC transporter superfamily.

298596:BI350 RS09635
gene id: 298596:BI350_RS09635
uniprot id: A0A1D8JGE4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

298596:BI350 RS12410
gene id: 298596:BI350_RS12410
uniprot id: A0A1D8JKK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

298596:BI350 RS12705
gene id: 298596:BI350_RS12705
uniprot id: A0A1D8JHY6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

298596:BI350 RS03475
gene id: 298596:BI350_RS03475
uniprot id: A0A1D8JDI3
names: Similarity
messages: Belongs to the YjdM family.

298596:BI350 RS14125
gene id: 298596:BI350_RS14125
uniprot id: A0A1D8JIM0
names: Similarity
messages: Belongs to the OsmC/Ohr family.

298596:BI350 RS03430
gene id: 298596:BI350_RS03430
uniprot id: A0A1D8JDF0
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS02370
gene id: 298596:BI350_RS02370
uniprot id: A0A1D8JCX8
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

298596:BI350 RS04490
gene id: 298596:BI350_RS04490
uniprot id: A0A1D8JDX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

298596:BI350 RS07045
gene id: 298596:BI350_RS07045
uniprot id: A0A1D8JF28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

298596:BI350 RS12620
gene id: 298596:BI350_RS12620
uniprot id: A0A1D8JHU7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

298596:BI350 RS15420
gene id: 298596:BI350_RS15420
uniprot id: A0A1D8JJB1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

298596:BI350 RS06750
gene id: 298596:BI350_RS06750
uniprot id: A0A1D8JEY1
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

298596:BI350 RS02105
gene id: 298596:BI350_RS02105
uniprot id: A0A1D8JCT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

298596:BI350 RS10295
gene id: 298596:BI350_RS10295
uniprot id: A0A1D8JGR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

298596:BI350 RS13840
gene id: 298596:BI350_RS13840
uniprot id: A0A1D8JII2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

298596:BI350 RS07235
gene id: 298596:BI350_RS07235
uniprot id: A0A1D8JF66
names: Similarity
messages: Belongs to the leucine-binding protein family.

298596:BI350 RS05955
gene id: 298596:BI350_RS05955
uniprot id: A0A1D8JEJ6
names: Similarity
messages: Belongs to the GbsR family.

298596:BI350 RS14355
gene id: 298596:BI350_RS14355
uniprot id: A0A1D8JIQ3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

298596:BI350 RS15555
gene id: 298596:BI350_RS15555
uniprot id: A0A1D8JJD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS06655
gene id: 298596:BI350_RS06655
uniprot id: A0A1D8JEW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

298596:BI350 RS08595
gene id: 298596:BI350_RS08595
uniprot id: A0A1D8JFW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. L-carnitine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.
messages: Cytoplasm
messages: Homodimer.

298596:BI350 RS13255
gene id: 298596:BI350_RS13255
uniprot id: A0A1D8JI66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS06555
gene id: 298596:BI350_RS06555
uniprot id: A0A1D8JEU5
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

298596:BI350 RS12645
gene id: 298596:BI350_RS12645
uniprot id: A0A1D8JHV6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

298596:BI350 RS11215
gene id: 298596:BI350_RS11215
uniprot id: A0A1D8JKG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

298596:BI350 RS12660
gene id: 298596:BI350_RS12660
uniprot id: A0A1D8JHV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

298596:BI350 RS14360
gene id: 298596:BI350_RS14360
uniprot id: A0A1D8JIS3
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS01635
gene id: 298596:BI350_RS01635
uniprot id: A0A1D8JCK6
names: Similarity
messages: Belongs to the peptidase S9A family.

298596:BI350 RS08665
gene id: 298596:BI350_RS08665
uniprot id: A0A1D8JFV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

298596:BI350 RS00980
gene id: 298596:BI350_RS00980
uniprot id: A0A1D8JCA5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

298596:BI350 RS02120
gene id: 298596:BI350_RS02120
uniprot id: A0A1D8JCU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

298596:BI350 RS12025
gene id: 298596:BI350_RS12025
uniprot id: A0A1D8JHI8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

298596:BI350 RS03910
gene id: 298596:BI350_RS03910
uniprot id: A0A1D8JDM8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

298596:BI350 RS03460
gene id: 298596:BI350_RS03460
uniprot id: A0A1D8JDF4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

298596:BI350 RS16370
gene id: 298596:BI350_RS16370
uniprot id: A0A1D8JJT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS09750
gene id: 298596:BI350_RS09750
uniprot id: A0A1D8JGH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

298596:BI350 RS04830
gene id: 298596:BI350_RS04830
uniprot id: A0A1D8JE39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS04795
gene id: 298596:BI350_RS04795
uniprot id: A0A1D8JE13
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

298596:BI350 RS06730
gene id: 298596:BI350_RS06730
uniprot id: A0A1D8JEZ5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS11545
gene id: 298596:BI350_RS11545
uniprot id: A0A1D8JHE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

298596:BI350 RS14320
gene id: 298596:BI350_RS14320
uniprot id: A0A1D8JIP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS02255
gene id: 298596:BI350_RS02255
uniprot id: A0A1D8JCW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

298596:BI350 RS06140
gene id: 298596:BI350_RS06140
uniprot id: A0A1D8JEP4
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

298596:BI350 RS10420
gene id: 298596:BI350_RS10420
uniprot id: A0A1D8JGS2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

298596:BI350 RS06540
gene id: 298596:BI350_RS06540
uniprot id: A0A1D8JEU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

298596:BI350 RS15095
gene id: 298596:BI350_RS15095
uniprot id: A0A1D8JJ49
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

298596:BI350 RS13895
gene id: 298596:BI350_RS13895
uniprot id: A0A1D8JII5
names: Similarity
messages: Belongs to the FlgM family.

298596:BI350 RS14155
gene id: 298596:BI350_RS14155
uniprot id: A0A1D8JIP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

298596:BI350 RS02260
gene id: 298596:BI350_RS02260
uniprot id: A0A1D8JCW7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

298596:BI350 RS04360
gene id: 298596:BI350_RS04360
uniprot id: A0A1D8JDT8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

298596:BI350 RS00285
gene id: 298596:BI350_RS00285
uniprot id: A0A1D8JBZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

298596:BI350 RS12490
gene id: 298596:BI350_RS12490
uniprot id: A0A1D8JHU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

298596:BI350 RS14205
gene id: 298596:BI350_RS14205
uniprot id: A0A1D8JKP7
names: Similarity
messages: Belongs to the peptidase S9A family.

298596:BI350 RS14835
gene id: 298596:BI350_RS14835
uniprot id: A0A1D8JJ05
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.

298596:BI350 RS05445
gene id: 298596:BI350_RS05445
uniprot id: A0A1D8JK58
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

298596:BI350 RS02665
gene id: 298596:BI350_RS02665
uniprot id: A0A1D8JD37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

298596:BI350 RS16290
gene id: 298596:BI350_RS16290
uniprot id: A0A1D8JJS4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

298596:BI350 RS04845
gene id: 298596:BI350_RS04845
uniprot id: A0A1D8JE36
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

298596:BI350 RS10565
gene id: 298596:BI350_RS10565
uniprot id: A0A1D8JGU5
names: Similarity
messages: Belongs to the UPF0473 family.

298596:BI350 RS10210
gene id: 298596:BI350_RS10210
uniprot id: A0A1D8JGN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. CshB subfamily.
messages: Cytoplasm
messages: Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.

298596:BI350 RS08840
gene id: 298596:BI350_RS08840
uniprot id: A0A1D8JFY5
names: Subcellular Location Annotation
messages: Membrane

298596:BI350 RS10275
gene id: 298596:BI350_RS10275
uniprot id: A0A1D8JGN7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

298596:BI350 RS14770
gene id: 298596:BI350_RS14770
uniprot id: A0A1D8JIY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

298596:BI350 RS07720
gene id: 298596:BI350_RS07720
uniprot id: A0A1D8JFE8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

298596:BI350 RS14430
gene id: 298596:BI350_RS14430
uniprot id: A0A1D8JIS4
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

298596:BI350 RS04910
gene id: 298596:BI350_RS04910
uniprot id: A0A1D8JE61
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

298596:BI350 RS06795
gene id: 298596:BI350_RS06795
uniprot id: A0A1D8JEY8
names: Function
messages: Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.

298596:BI350 RS02495
gene id: 298596:BI350_RS02495
uniprot id: A0A1D8JD06
names: Similarity
messages: Belongs to the SAICAR synthetase family.

298596:BI350 RS10515
gene id: 298596:BI350_RS10515
uniprot id: A0A1D8JGT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

298596:BI350 RS09735
gene id: 298596:BI350_RS09735
uniprot id: A0A1D8JGD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

298596:BI350 RS12760
gene id: 298596:BI350_RS12760
uniprot id: A0A1D8JHZ8
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

298596:BI350 RS08290
gene id: 298596:BI350_RS08290
uniprot id: A0A1D8JFP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.