2968969:I6G34 RS17260
gene id: 2968969:I6G34_RS17260
uniprot id: A0A2U9NB89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2968969:I6G34 RS09585
gene id: 2968969:I6G34_RS09585
uniprot id: A0A2U9NDM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

2968969:I6G34 RS14760
gene id: 2968969:I6G34_RS14760
uniprot id: A0A2U9NIC6
names: Subunit
messages: Monomer. Interacts with PqqE.

2968969:I6G34 RS09845
gene id: 2968969:I6G34_RS09845
uniprot id: A0A2U9NDH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2968969:I6G34 RS05365
gene id: 2968969:I6G34_RS05365
uniprot id: A0A2U9NFY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

2968969:I6G34 RS08925
gene id: 2968969:I6G34_RS08925
uniprot id: A0A2U9NGM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2968969:I6G34 RS12115
gene id: 2968969:I6G34_RS12115
uniprot id: A0A2U9NEQ5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2968969:I6G34 RS08835
gene id: 2968969:I6G34_RS08835
uniprot id: A0A2U9NE66
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2968969:I6G34 RS07225
gene id: 2968969:I6G34_RS07225
uniprot id: A0A2U9NH92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

2968969:I6G34 RS08855
gene id: 2968969:I6G34_RS08855
uniprot id: A0A2U9NE16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2968969:I6G34 RS10350
gene id: 2968969:I6G34_RS10350
uniprot id: A0A2U9NFS6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

2968969:I6G34 RS10425
gene id: 2968969:I6G34_RS10425
uniprot id: A0A2U9ND19
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2968969:I6G34 RS13160
gene id: 2968969:I6G34_RS13160
uniprot id: A0A2U9NBL3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2968969:I6G34 RS01235
gene id: 2968969:I6G34_RS01235
uniprot id: A0A5P9JPE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

2968969:I6G34 RS16090
gene id: 2968969:I6G34_RS16090
uniprot id: A0A2U9NCE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2968969:I6G34 RS00410
gene id: 2968969:I6G34_RS00410
uniprot id: A0A2U9N8K4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2968969:I6G34 RS10225
gene id: 2968969:I6G34_RS10225
uniprot id: A0A2U9NDA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2968969:I6G34 RS18190
gene id: 2968969:I6G34_RS18190
uniprot id: A0A5P9JLC7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2968969:I6G34 RS11525
gene id: 2968969:I6G34_RS11525
uniprot id: A0A2U9NCI3
names: Subcellular Location Annotation
messages: Membrane

2968969:I6G34 RS10895
gene id: 2968969:I6G34_RS10895
uniprot id: A0A2U9NCU2
names: Function
names: Similarity
messages: An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
messages: Belongs to the SdhE FAD assembly factor family.

2968969:I6G34 RS02120
gene id: 2968969:I6G34_RS02120
uniprot id: A0A2U9N9A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

2968969:I6G34 RS12005
gene id: 2968969:I6G34_RS12005
uniprot id: A0A2U9NEE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

2968969:I6G34 RS09525
gene id: 2968969:I6G34_RS09525
uniprot id: A0A5P9JEI2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2968969:I6G34 RS00810
gene id: 2968969:I6G34_RS00810
uniprot id: A0A5P9JP83
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

2968969:I6G34 RS17265
gene id: 2968969:I6G34_RS17265
uniprot id: A0A2U9NBS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2968969:I6G34 RS17425
gene id: 2968969:I6G34_RS17425
uniprot id: A0A5P9JM96
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

2968969:I6G34 RS08370
gene id: 2968969:I6G34_RS08370
uniprot id: A0A2U9NFH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

2968969:I6G34 RS18350
gene id: 2968969:I6G34_RS18350
uniprot id: A0A2U9N8M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2968969:I6G34 RS05035
gene id: 2968969:I6G34_RS05035
uniprot id: A0A5P9JF97
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2968969:I6G34 RS05745
gene id: 2968969:I6G34_RS05745
uniprot id: A0A2U9NFN9
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

2968969:I6G34 RS19540
gene id: 2968969:I6G34_RS19540
uniprot id: A0A5P9JMS8
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

2968969:I6G34 RS16680
gene id: 2968969:I6G34_RS16680
uniprot id: A0A2U9N9G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

2968969:I6G34 RS08235
gene id: 2968969:I6G34_RS08235
uniprot id: A0A2U9NGQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2968969:I6G34 RS20105
gene id: 2968969:I6G34_RS20105
uniprot id: A0A5P9JPJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ureidoglycolate lyase family.
messages: Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
messages: Homodimer.

2968969:I6G34 RS03730
gene id: 2968969:I6G34_RS03730
uniprot id: A0A2U9NIQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

2968969:I6G34 RS20275
gene id: 2968969:I6G34_RS20275
uniprot id: A0A2U9N7S6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

2968969:I6G34 RS18380
gene id: 2968969:I6G34_RS18380
uniprot id: A0A2U9N8N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

2968969:I6G34 RS09475
gene id: 2968969:I6G34_RS09475
uniprot id: A0A5P9JHD3
names: Subcellular Location Annotation
messages: Membrane

2968969:I6G34 RS17715
gene id: 2968969:I6G34_RS17715
uniprot id: A0A2U9NHF6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2968969:I6G34 RS11345
gene id: 2968969:I6G34_RS11345
uniprot id: A0A5P9JH16
names: Similarity
messages: Belongs to the UPF0260 family.

2968969:I6G34 RS09840
gene id: 2968969:I6G34_RS09840
uniprot id: A0A2U9NDF9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

2968969:I6G34 RS08705
gene id: 2968969:I6G34_RS08705
uniprot id: A0A2U9NE54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2968969:I6G34 RS17320
gene id: 2968969:I6G34_RS17320
uniprot id: A0A2U9N946
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

2968969:I6G34 RS07775
gene id: 2968969:I6G34_RS07775
uniprot id: A0A2U9NEG2
names: Similarity
messages: Belongs to the UPF0758 family.

2968969:I6G34 RS14730
gene id: 2968969:I6G34_RS14730
uniprot id: A0A2U9NCZ7
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

2968969:I6G34 RS05310
gene id: 2968969:I6G34_RS05310
uniprot id: A0A2U9NFP8
names: Similarity
messages: Belongs to the glutamine synthetase family.

2968969:I6G34 RS08800
gene id: 2968969:I6G34_RS08800
uniprot id: A0A2U9NE17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2968969:I6G34 RS20560
gene id: 2968969:I6G34_RS20560
uniprot id: A0A2U9N9U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

2968969:I6G34 RS04415
gene id: 2968969:I6G34_RS04415
uniprot id: A0A2U9NGB4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2968969:I6G34 RS09505
gene id: 2968969:I6G34_RS09505
uniprot id: A0A2U9NG90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

2968969:I6G34 RS11570
gene id: 2968969:I6G34_RS11570
uniprot id: A0A2U9NDP1
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

2968969:I6G34 RS08730
gene id: 2968969:I6G34_RS08730
uniprot id: A0A2U9NE00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

2968969:I6G34 RS13805
gene id: 2968969:I6G34_RS13805
uniprot id: A0A2U9NBB3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2968969:I6G34 RS08850
gene id: 2968969:I6G34_RS08850
uniprot id: A0A2U9NE06
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2968969:I6G34 RS13810
gene id: 2968969:I6G34_RS13810
uniprot id: A0A2U9NDI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

2968969:I6G34 RS13465
gene id: 2968969:I6G34_RS13465
uniprot id: A0A2U9NBH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

2968969:I6G34 RS17720
gene id: 2968969:I6G34_RS17720
uniprot id: A0A5P9JLV4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2968969:I6G34 RS20680
gene id: 2968969:I6G34_RS20680
uniprot id: A0A5P9JI04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2968969:I6G34 RS02550
gene id: 2968969:I6G34_RS02550
uniprot id: A0A5P9JMI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

2968969:I6G34 RS01570
gene id: 2968969:I6G34_RS01570
uniprot id: A0A2U9NJ06
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

2968969:I6G34 RS04270
gene id: 2968969:I6G34_RS04270
uniprot id: A0A2U9NIM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2968969:I6G34 RS17200
gene id: 2968969:I6G34_RS17200
uniprot id: A0A2U9N986
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

2968969:I6G34 RS06895
gene id: 2968969:I6G34_RS06895
uniprot id: A0A2U9NEY4
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

2968969:I6G34 RS13695
gene id: 2968969:I6G34_RS13695
uniprot id: A0A5P9JH15
names: Similarity
messages: Belongs to the citrate synthase family.

2968969:I6G34 RS00535
gene id: 2968969:I6G34_RS00535
uniprot id: A0A2U9N7G2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

2968969:I6G34 RS14795
gene id: 2968969:I6G34_RS14795
uniprot id: A0A2U9NCY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

2968969:I6G34 RS00700
gene id: 2968969:I6G34_RS00700
uniprot id: A0A5P9JNJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2968969:I6G34 RS04025
gene id: 2968969:I6G34_RS04025
uniprot id: A0A2U9NGN4
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

2968969:I6G34 RS08815
gene id: 2968969:I6G34_RS08815
uniprot id: A0A2U9NGB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2968969:I6G34 RS10795
gene id: 2968969:I6G34_RS10795
uniprot id: A0A2U9NCW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

2968969:I6G34 RS08055
gene id: 2968969:I6G34_RS08055
uniprot id: A0A2U9NEF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

2968969:I6G34 RS10195
gene id: 2968969:I6G34_RS10195
uniprot id: A0A5P9JEX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

2968969:I6G34 RS07700
gene id: 2968969:I6G34_RS07700
uniprot id: A0A5P9JIH2
names: Similarity
messages: Belongs to the RutC family.

2968969:I6G34 RS17125
gene id: 2968969:I6G34_RS17125
uniprot id: A0A5P9JM35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2968969:I6G34 RS00655
gene id: 2968969:I6G34_RS00655
uniprot id: A0A2U9N9B5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2968969:I6G34 RS04020
gene id: 2968969:I6G34_RS04020
uniprot id: A0A5P9JNG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

2968969:I6G34 RS18395
gene id: 2968969:I6G34_RS18395
uniprot id: A0A2U9NAQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2968969:I6G34 RS03135
gene id: 2968969:I6G34_RS03135
uniprot id: A0A2U9NIY8
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

2968969:I6G34 RS08770
gene id: 2968969:I6G34_RS08770
uniprot id: A0A2U9NGF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2968969:I6G34 RS10430
gene id: 2968969:I6G34_RS10430
uniprot id: A0A2U9ND52
names: Similarity
messages: Belongs to the glutathione peroxidase family.

2968969:I6G34 RS11490
gene id: 2968969:I6G34_RS11490
uniprot id: A0A2U9NF34
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2968969:I6G34 RS08875
gene id: 2968969:I6G34_RS08875
uniprot id: A0A2U9NGM9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2968969:I6G34 RS14855
gene id: 2968969:I6G34_RS14855
uniprot id: A0A2U9NDC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

2968969:I6G34 RS08515
gene id: 2968969:I6G34_RS08515
uniprot id: A0A5P9JFB6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2968969:I6G34 RS11925
gene id: 2968969:I6G34_RS11925
uniprot id: A0A5P9JG07
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2968969:I6G34 RS20375
gene id: 2968969:I6G34_RS20375
uniprot id: A0A2U9N7V1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

2968969:I6G34 RS03185
gene id: 2968969:I6G34_RS03185
uniprot id: A0A2U9NGW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

2968969:I6G34 RS03540
gene id: 2968969:I6G34_RS03540
uniprot id: A0A2U9NGN9
names: Similarity
messages: Belongs to the GSP E family.

2968969:I6G34 RS18055
gene id: 2968969:I6G34_RS18055
uniprot id: A0A5P9JNA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

2968969:I6G34 RS07710
gene id: 2968969:I6G34_RS07710
uniprot id: A0A2U9NGV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2968969:I6G34 RS10785
gene id: 2968969:I6G34_RS10785
uniprot id: A0A2U9NF89
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

2968969:I6G34 RS11395
gene id: 2968969:I6G34_RS11395
uniprot id: A0A2U9NCK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

2968969:I6G34 RS08380
gene id: 2968969:I6G34_RS08380
uniprot id: A0A2U9NE90
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2968969:I6G34 RS08795
gene id: 2968969:I6G34_RS08795
uniprot id: A0A2U9NDY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2968969:I6G34 RS10090
gene id: 2968969:I6G34_RS10090
uniprot id: A0A2U9NDG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2968969:I6G34 RS18370
gene id: 2968969:I6G34_RS18370
uniprot id: A0A2U9N8P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2968969:I6G34 RS19840
gene id: 2968969:I6G34_RS19840
uniprot id: A0A2U9N813
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

2968969:I6G34 RS01745
gene id: 2968969:I6G34_RS01745
uniprot id: A0A2U9N732
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2968969:I6G34 RS10130
gene id: 2968969:I6G34_RS10130
uniprot id: A0A2U9NFW8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

2968969:I6G34 RS15610
gene id: 2968969:I6G34_RS15610
uniprot id: A0A5P9JIK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

2968969:I6G34 RS10005
gene id: 2968969:I6G34_RS10005
uniprot id: A0A2U9NFL3
names: Function
messages: Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.

2968969:I6G34 RS00105
gene id: 2968969:I6G34_RS00105
uniprot id: A0A2U9NHA3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2968969:I6G34 RS20675
gene id: 2968969:I6G34_RS20675
uniprot id: A0A5P9JIC4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2968969:I6G34 RS17050
gene id: 2968969:I6G34_RS17050
uniprot id: A0A2U9N9B1
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

2968969:I6G34 RS07195
gene id: 2968969:I6G34_RS07195
uniprot id: A0A2U9NG37
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

2968969:I6G34 RS08845
gene id: 2968969:I6G34_RS08845
uniprot id: A0A2U9NDX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2968969:I6G34 RS18390
gene id: 2968969:I6G34_RS18390
uniprot id: A0A2U9NAT2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

2968969:I6G34 RS20185
gene id: 2968969:I6G34_RS20185
uniprot id: A0A2U9N9Z9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2968969:I6G34 RS08980
gene id: 2968969:I6G34_RS08980
uniprot id: A0A2U9NGL0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

2968969:I6G34 RS17120
gene id: 2968969:I6G34_RS17120
uniprot id: A0A2U9N983
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

2968969:I6G34 RS10600
gene id: 2968969:I6G34_RS10600
uniprot id: A0A2U9NCZ2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

2968969:I6G34 RS18185
gene id: 2968969:I6G34_RS18185
uniprot id: A0A2U9NA08
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

2968969:I6G34 RS04940
gene id: 2968969:I6G34_RS04940
uniprot id: A0A5P9JNS4
names: Subcellular Location Annotation
messages: Membrane

2968969:I6G34 RS04090
gene id: 2968969:I6G34_RS04090
uniprot id: A0A2U9NGH9
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

2968969:I6G34 RS19535
gene id: 2968969:I6G34_RS19535
uniprot id: A0A5P9JND6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

2968969:I6G34 RS13185
gene id: 2968969:I6G34_RS13185
uniprot id: A0A2U9NHH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

2968969:I6G34 RS04935
gene id: 2968969:I6G34_RS04935
uniprot id: A0A2U9NG67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

2968969:I6G34 RS09900
gene id: 2968969:I6G34_RS09900
uniprot id: A0A2U9NDG3
names: Subcellular Location Annotation
messages: Cytoplasm

2968969:I6G34 RS08745
gene id: 2968969:I6G34_RS08745
uniprot id: A0A2U9NE01
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2968969:I6G34 RS07430
gene id: 2968969:I6G34_RS07430
uniprot id: A0A2U9NEQ3
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

2968969:I6G34 RS06000
gene id: 2968969:I6G34_RS06000
uniprot id: A0A2U9NFU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2968969:I6G34 RS14680
gene id: 2968969:I6G34_RS14680
uniprot id: A0A2U9ND09
names: Similarity
messages: Belongs to the OsmC/Ohr family.

2968969:I6G34 RS08685
gene id: 2968969:I6G34_RS08685
uniprot id: A0A2U9NEA3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2968969:I6G34 RS13500
gene id: 2968969:I6G34_RS13500
uniprot id: A0A2U9NBK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

2968969:I6G34 RS11615
gene id: 2968969:I6G34_RS11615
uniprot id: A0A5P9JH62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

2968969:I6G34 RS04905
gene id: 2968969:I6G34_RS04905
uniprot id: A0A2U9NG34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

2968969:I6G34 RS12025
gene id: 2968969:I6G34_RS12025
uniprot id: A0A2U9NCC9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

2968969:I6G34 RS00440
gene id: 2968969:I6G34_RS00440
uniprot id: A0A5P9JL52
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

2968969:I6G34 RS03565
gene id: 2968969:I6G34_RS03565
uniprot id: A0A5P9JN65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

2968969:I6G34 RS10155
gene id: 2968969:I6G34_RS10155
uniprot id: A0A2U9ND69
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

2968969:I6G34 RS11210
gene id: 2968969:I6G34_RS11210
uniprot id: A0A2U9NCL3
names: Similarity
messages: Belongs to the peptidase C40 family.

2968969:I6G34 RS02620
gene id: 2968969:I6G34_RS02620
uniprot id: A0A2U9N7P6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

2968969:I6G34 RS17485
gene id: 2968969:I6G34_RS17485
uniprot id: A0A2U9NAD5
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

2968969:I6G34 RS17965
gene id: 2968969:I6G34_RS17965
uniprot id: A0A5P9JMK9
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

2968969:I6G34 RS10765
gene id: 2968969:I6G34_RS10765
uniprot id: A0A2U9NCZ4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2968969:I6G34 RS08080
gene id: 2968969:I6G34_RS08080
uniprot id: A0A5P9JDG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

2968969:I6G34 RS06245
gene id: 2968969:I6G34_RS06245
uniprot id: A0A2U9NHV9
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

2968969:I6G34 RS16555
gene id: 2968969:I6G34_RS16555
uniprot id: A0A2U9NBM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

2968969:I6G34 RS17180
gene id: 2968969:I6G34_RS17180
uniprot id: A0A2U9NAI7
names: Similarity
messages: Belongs to the MotB family.

2968969:I6G34 RS14575
gene id: 2968969:I6G34_RS14575
uniprot id: A0A2U9NAV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

2968969:I6G34 RS05370
gene id: 2968969:I6G34_RS05370
uniprot id: A0A2U9NH04
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

2968969:I6G34 RS08825
gene id: 2968969:I6G34_RS08825
uniprot id: A0A2U9NGP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2968969:I6G34 RS07160
gene id: 2968969:I6G34_RS07160
uniprot id: A0A2U9NEW2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

2968969:I6G34 RS02690
gene id: 2968969:I6G34_RS02690
uniprot id: A0A2U9N6K6
names: Subcellular Location Annotation
messages: Membrane

2968969:I6G34 RS04915
gene id: 2968969:I6G34_RS04915
uniprot id: A0A2U9NI89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

2968969:I6G34 RS20490
gene id: 2968969:I6G34_RS20490
uniprot id: A0A2U9N7Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

2968969:I6G34 RS05830
gene id: 2968969:I6G34_RS05830
uniprot id: A0A5P9JFQ8
names: Subcellular Location Annotation
messages: Membrane

2968969:I6G34 RS09985
gene id: 2968969:I6G34_RS09985
uniprot id: A0A2U9ND97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2968969:I6G34 RS15860
gene id: 2968969:I6G34_RS15860
uniprot id: A0A2U9NC89
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

2968969:I6G34 RS20085
gene id: 2968969:I6G34_RS20085
uniprot id: A0A2U9NAE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

2968969:I6G34 RS07135
gene id: 2968969:I6G34_RS07135
uniprot id: A0A2U9NHI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2968969:I6G34 RS00435
gene id: 2968969:I6G34_RS00435
uniprot id: A0A2U9N9M6
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

2968969:I6G34 RS18290
gene id: 2968969:I6G34_RS18290
uniprot id: A0A2U9NB82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homodimer.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

2968969:I6G34 RS17135
gene id: 2968969:I6G34_RS17135
uniprot id: A0A2U9N972
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2968969:I6G34 RS19945
gene id: 2968969:I6G34_RS19945
uniprot id: A0A5P9JNJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

2968969:I6G34 RS12105
gene id: 2968969:I6G34_RS12105
uniprot id: A0A2U9NEC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

2968969:I6G34 RS02035
gene id: 2968969:I6G34_RS02035
uniprot id: A0A2U9N800
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2968969:I6G34 RS07565
gene id: 2968969:I6G34_RS07565
uniprot id: A0A2U9NGY9
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

2968969:I6G34 RS00845
gene id: 2968969:I6G34_RS00845
uniprot id: A0A5P9JPW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Membrane

2968969:I6G34 RS00490
gene id: 2968969:I6G34_RS00490
uniprot id: A0A2U9N9E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

2968969:I6G34 RS16370
gene id: 2968969:I6G34_RS16370
uniprot id: A0A2U9N9Q7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2968969:I6G34 RS07725
gene id: 2968969:I6G34_RS07725
uniprot id: A0A2U9NEH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

2968969:I6G34 RS02765
gene id: 2968969:I6G34_RS02765
uniprot id: A0A2U9N6K7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2968969:I6G34 RS09925
gene id: 2968969:I6G34_RS09925
uniprot id: A0A5P9JN79
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

2968969:I6G34 RS16010
gene id: 2968969:I6G34_RS16010
uniprot id: A0A2U9NA61
names: Similarity
messages: Belongs to the GST superfamily.

2968969:I6G34 RS17975
gene id: 2968969:I6G34_RS17975
uniprot id: A0A2U9N8S5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2968969:I6G34 RS17545
gene id: 2968969:I6G34_RS17545
uniprot id: A0A2U9N938
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2968969:I6G34 RS09980
gene id: 2968969:I6G34_RS09980
uniprot id: A0A5P9JJX1
names: Similarity
messages: Belongs to the BolA/IbaG family.

2968969:I6G34 RS15355
gene id: 2968969:I6G34_RS15355
uniprot id: A0A2U9NAC9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2968969:I6G34 RS08700
gene id: 2968969:I6G34_RS08700
uniprot id: A0A2U9NE40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2968969:I6G34 RS07080
gene id: 2968969:I6G34_RS07080
uniprot id: A0A5P9JCW1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2968969:I6G34 RS16420
gene id: 2968969:I6G34_RS16420
uniprot id: A0A5P9JKZ6
names: Subcellular Location Annotation
messages: Membrane

2968969:I6G34 RS17310
gene id: 2968969:I6G34_RS17310
uniprot id: A0A2U9NB86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2968969:I6G34 RS10870
gene id: 2968969:I6G34_RS10870
uniprot id: A0A5P9JNS8
names: Similarity
messages: Belongs to the leucine-binding protein family.

2968969:I6G34 RS17785
gene id: 2968969:I6G34_RS17785
uniprot id: A0A2U9NB19
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2968969:I6G34 RS12235
gene id: 2968969:I6G34_RS12235
uniprot id: A0A2U9NEE5
names: Similarity
messages: Belongs to the HAM1 NTPase family.

2968969:I6G34 RS04125
gene id: 2968969:I6G34_RS04125
uniprot id: A0A5P9JNI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

2968969:I6G34 RS03005
gene id: 2968969:I6G34_RS03005
uniprot id: A0A5P9JRE1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2968969:I6G34 RS00335
gene id: 2968969:I6G34_RS00335
uniprot id: A0A5P9JNB9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

2968969:I6G34 RS16925
gene id: 2968969:I6G34_RS16925
uniprot id: A0A2U9N9D2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2968969:I6G34 RS02970
gene id: 2968969:I6G34_RS02970
uniprot id: A0A2U9NJ02
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

2968969:I6G34 RS16895
gene id: 2968969:I6G34_RS16895
uniprot id: A0A5P9JS84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2968969:I6G34 RS02095
gene id: 2968969:I6G34_RS02095
uniprot id: A0A5P9JM97
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2968969:I6G34 RS00710
gene id: 2968969:I6G34_RS00710
uniprot id: A0A2U9N7C8
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

2968969:I6G34 RS05400
gene id: 2968969:I6G34_RS05400
uniprot id: A0A2U9NI34
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

2968969:I6G34 RS10540
gene id: 2968969:I6G34_RS10540
uniprot id: A0A2U9ND29
names: Similarity
messages: Belongs to the pyruvate kinase family.

2968969:I6G34 RS08110
gene id: 2968969:I6G34_RS08110
uniprot id: A0A5P9JGE7
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

2968969:I6G34 RS16045
gene id: 2968969:I6G34_RS16045
uniprot id: A0A2U9NBC9
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

2968969:I6G34 RS02770
gene id: 2968969:I6G34_RS02770
uniprot id: A0A5P9JPM9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

2968969:I6G34 RS10060
gene id: 2968969:I6G34_RS10060
uniprot id: A0A2U9NDD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

2968969:I6G34 RS17385
gene id: 2968969:I6G34_RS17385
uniprot id: A0A5P9JN30
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

2968969:I6G34 RS03665
gene id: 2968969:I6G34_RS03665
uniprot id: A0A2U9NGS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

2968969:I6G34 RS11970
gene id: 2968969:I6G34_RS11970
uniprot id: A0A2U9NC66
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2968969:I6G34 RS10750
gene id: 2968969:I6G34_RS10750
uniprot id: A0A2U9ND50
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2968969:I6G34 RS07770
gene id: 2968969:I6G34_RS07770
uniprot id: A0A5P9JFV5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2968969:I6G34 RS01320
gene id: 2968969:I6G34_RS01320
uniprot id: A0A2U9N797
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2968969:I6G34 RS20555
gene id: 2968969:I6G34_RS20555
uniprot id: A0A2U9NH77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

2968969:I6G34 RS15420
gene id: 2968969:I6G34_RS15420
uniprot id: A0A5P9JIF5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

2968969:I6G34 RS02400
gene id: 2968969:I6G34_RS02400
uniprot id: A0A2U9N943
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2968969:I6G34 RS15815
gene id: 2968969:I6G34_RS15815
uniprot id: A0A2U9NA51
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

2968969:I6G34 RS09940
gene id: 2968969:I6G34_RS09940
uniprot id: A0A2U9NDE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

2968969:I6G34 RS17250
gene id: 2968969:I6G34_RS17250
uniprot id: A0A2U9N976
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

2968969:I6G34 RS10235
gene id: 2968969:I6G34_RS10235
uniprot id: A0A2U9NFI8
names: Similarity
messages: Belongs to the bacterioferritin family.

2968969:I6G34 RS02420
gene id: 2968969:I6G34_RS02420
uniprot id: A0A5P9JPH5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2968969:I6G34 RS01580
gene id: 2968969:I6G34_RS01580
uniprot id: A0A5P9JLQ4
names: Subcellular Location Annotation
messages: Membrane

2968969:I6G34 RS17590
gene id: 2968969:I6G34_RS17590
uniprot id: A0A2U9NAC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

2968969:I6G34 RS11475
gene id: 2968969:I6G34_RS11475
uniprot id: A0A2U9NEQ6
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

2968969:I6G34 RS06370
gene id: 2968969:I6G34_RS06370
uniprot id: A0A2U9NF93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2968969:I6G34 RS19915
gene id: 2968969:I6G34_RS19915
uniprot id: A0A2U9NA14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

2968969:I6G34 RS17015
gene id: 2968969:I6G34_RS17015
uniprot id: A0A2U9N9A1
names: Similarity
messages: Belongs to the FrmR/RcnR family.

2968969:I6G34 RS14965
gene id: 2968969:I6G34_RS14965
uniprot id: A0A2U9NDB0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

2968969:I6G34 RS03535
gene id: 2968969:I6G34_RS03535
uniprot id: A0A2U9NJ88
names: Similarity
messages: Belongs to the GSP E family.

2968969:I6G34 RS13735
gene id: 2968969:I6G34_RS13735
uniprot id: A0A2U9NBC7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

2968969:I6G34 RS00850
gene id: 2968969:I6G34_RS00850
uniprot id: A0A5P9JLL5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

2968969:I6G34 RS16940
gene id: 2968969:I6G34_RS16940
uniprot id: A0A2U9N9E5
names: Caution
names: Function
names: Similarity
messages: Belongs to the bacterial renalase family.
messages: Catalyzes the oxidation of the 1,2-dihydro- and 1,6-dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P)+. May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2968969:I6G34 RS10100
gene id: 2968969:I6G34_RS10100
uniprot id: A0A2U9ND78
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

2968969:I6G34 RS13715
gene id: 2968969:I6G34_RS13715
uniprot id: A0A2U9NBG8
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

2968969:I6G34 RS00825
gene id: 2968969:I6G34_RS00825
uniprot id: A0A5P9JNL2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2968969:I6G34 RS18365
gene id: 2968969:I6G34_RS18365
uniprot id: A0A2U9N8L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2968969:I6G34 RS08115
gene id: 2968969:I6G34_RS08115
uniprot id: A0A2U9NEQ0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

2968969:I6G34 RS08870
gene id: 2968969:I6G34_RS08870
uniprot id: A0A2U9NGD6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2968969:I6G34 RS17755
gene id: 2968969:I6G34_RS17755
uniprot id: A0A5P9JN46
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2968969:I6G34 RS17725
gene id: 2968969:I6G34_RS17725
uniprot id: A0A5P9JNB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

2968969:I6G34 RS08820
gene id: 2968969:I6G34_RS08820
uniprot id: A0A2U9NGE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2968969:I6G34 RS20340
gene id: 2968969:I6G34_RS20340
uniprot id: A0A2U9N9X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2968969:I6G34 RS12190
gene id: 2968969:I6G34_RS12190
uniprot id: A0A2U9NHI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

2968969:I6G34 RS04980
gene id: 2968969:I6G34_RS04980
uniprot id: A0A2U9NFV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

2968969:I6G34 RS03500
gene id: 2968969:I6G34_RS03500
uniprot id: A0A2U9NH61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

2968969:I6G34 RS00055
gene id: 2968969:I6G34_RS00055
uniprot id: A0A2U9N7N8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2968969:I6G34 RS20425
gene id: 2968969:I6G34_RS20425
uniprot id: A0A2U9N7Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2968969:I6G34 RS04040
gene id: 2968969:I6G34_RS04040
uniprot id: A0A2U9NGI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2968969:I6G34 RS11930
gene id: 2968969:I6G34_RS11930
uniprot id: A0A5P9JHD9
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

2968969:I6G34 RS08755
gene id: 2968969:I6G34_RS08755
uniprot id: A0A5P9JFF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2968969:I6G34 RS04930
gene id: 2968969:I6G34_RS04930
uniprot id: A0A2U9NFW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2968969:I6G34 RS12070
gene id: 2968969:I6G34_RS12070
uniprot id: A0A2U9NC50
names: Similarity
messages: Belongs to the Skp family.

2968969:I6G34 RS08595
gene id: 2968969:I6G34_RS08595
uniprot id: A0A2U9NE50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

2968969:I6G34 RS05625
gene id: 2968969:I6G34_RS05625
uniprot id: A0A2U9NGW4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2968969:I6G34 RS08390
gene id: 2968969:I6G34_RS08390
uniprot id: A0A2U9NJ65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

2968969:I6G34 RS09020
gene id: 2968969:I6G34_RS09020
uniprot id: A0A2U9NDZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

2968969:I6G34 RS15360
gene id: 2968969:I6G34_RS15360
uniprot id: A0A5P9JN93
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2968969:I6G34 RS17225
gene id: 2968969:I6G34_RS17225
uniprot id: A0A2U9N970
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

2968969:I6G34 RS08720
gene id: 2968969:I6G34_RS08720
uniprot id: A0A2U9NGH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2968969:I6G34 RS02465
gene id: 2968969:I6G34_RS02465
uniprot id: A0A2U9N7S2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily.
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.
messages: Homotetramer; dimer of dimers.

2968969:I6G34 RS17505
gene id: 2968969:I6G34_RS17505
uniprot id: A0A2U9N928
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2968969:I6G34 RS09630
gene id: 2968969:I6G34_RS09630
uniprot id: A0A5P9JHF8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2968969:I6G34 RS16110
gene id: 2968969:I6G34_RS16110
uniprot id: A0A2U9N9S0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2968969:I6G34 RS08810
gene id: 2968969:I6G34_RS08810
uniprot id: A0A2U9NE44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2968969:I6G34 RS14535
gene id: 2968969:I6G34_RS14535
uniprot id: A0A2U9NAW3
names: Similarity
messages: Belongs to the citrate synthase family.

2968969:I6G34 RS17315
gene id: 2968969:I6G34_RS17315
uniprot id: A0A2U9NBR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

2968969:I6G34 RS20380
gene id: 2968969:I6G34_RS20380
uniprot id: A0A2U9N7Q6
names: Similarity
messages: Belongs to the UPF0234 family.

2968969:I6G34 RS14530
gene id: 2968969:I6G34_RS14530
uniprot id: A0A5P9JJY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

2968969:I6G34 RS16630
gene id: 2968969:I6G34_RS16630
uniprot id: A0A2U9N9H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

2968969:I6G34 RS12080
gene id: 2968969:I6G34_RS12080
uniprot id: A0A2U9NDD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

2968969:I6G34 RS09150
gene id: 2968969:I6G34_RS09150
uniprot id: A0A2U9NDS7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2968969:I6G34 RS12205
gene id: 2968969:I6G34_RS12205
uniprot id: A0A2U9NC53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

2968969:I6G34 RS11635
gene id: 2968969:I6G34_RS11635
uniprot id: A0A2U9NCG9
names: Similarity
messages: Belongs to the UPF0270 family.

2968969:I6G34 RS08765
gene id: 2968969:I6G34_RS08765
uniprot id: A0A2U9NGC7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2968969:I6G34 RS17460
gene id: 2968969:I6G34_RS17460
uniprot id: A0A2U9NB87
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2968969:I6G34 RS20180
gene id: 2968969:I6G34_RS20180
uniprot id: A0A5P9JQM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

2968969:I6G34 RS07520
gene id: 2968969:I6G34_RS07520
uniprot id: A0A5P9JGE2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2968969:I6G34 RS03520
gene id: 2968969:I6G34_RS03520
uniprot id: A0A5P9JQP2
names: Subcellular Location Annotation
messages: Membrane

2968969:I6G34 RS17270
gene id: 2968969:I6G34_RS17270
uniprot id: A0A2U9N958
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

2968969:I6G34 RS03975
gene id: 2968969:I6G34_RS03975
uniprot id: A0A2U9NHR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

2968969:I6G34 RS19905
gene id: 2968969:I6G34_RS19905
uniprot id: A0A2U9N804
names: Subcellular Location Annotation
messages: Cytoplasm

2968969:I6G34 RS16025
gene id: 2968969:I6G34_RS16025
uniprot id: A0A2U9NC65
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

2968969:I6G34 RS09540
gene id: 2968969:I6G34_RS09540
uniprot id: A0A2U9NDN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2968969:I6G34 RS14790
gene id: 2968969:I6G34_RS14790
uniprot id: A0A5P9JKG8
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

2968969:I6G34 RS11575
gene id: 2968969:I6G34_RS11575
uniprot id: A0A2U9NCF1
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

2968969:I6G34 RS09045
gene id: 2968969:I6G34_RS09045
uniprot id: A0A2U9NE24
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

2968969:I6G34 RS00325
gene id: 2968969:I6G34_RS00325
uniprot id: A0A2U9N9G8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2968969:I6G34 RS00695
gene id: 2968969:I6G34_RS00695
uniprot id: A0A2U9N9G6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

2968969:I6G34 RS19020
gene id: 2968969:I6G34_RS19020
uniprot id: A0A2U9N8B5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2968969:I6G34 RS03855
gene id: 2968969:I6G34_RS03855
uniprot id: A0A2U9NGH3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2968969:I6G34 RS11370
gene id: 2968969:I6G34_RS11370
uniprot id: A0A2U9NDS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2968969:I6G34 RS10910
gene id: 2968969:I6G34_RS10910
uniprot id: A0A2U9NCT3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2968969:I6G34 RS11100
gene id: 2968969:I6G34_RS11100
uniprot id: A0A2U9NFA3
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

2968969:I6G34 RS08750
gene id: 2968969:I6G34_RS08750
uniprot id: A0A2U9NE33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2968969:I6G34 RS06420
gene id: 2968969:I6G34_RS06420
uniprot id: A0A2U9NF83
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

2968969:I6G34 RS00405
gene id: 2968969:I6G34_RS00405
uniprot id: A0A2U9N7H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

2968969:I6G34 RS03510
gene id: 2968969:I6G34_RS03510
uniprot id: A0A2U9NIT5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

2968969:I6G34 RS17110
gene id: 2968969:I6G34_RS17110
uniprot id: A0A5P9JP62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

2968969:I6G34 RS07335
gene id: 2968969:I6G34_RS07335
uniprot id: A0A2U9NET6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

2968969:I6G34 RS07480
gene id: 2968969:I6G34_RS07480
uniprot id: A0A2U9NJ70
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

2968969:I6G34 RS12670
gene id: 2968969:I6G34_RS12670
uniprot id: A0A2U9NBX7
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

2968969:I6G34 RS12130
gene id: 2968969:I6G34_RS12130
uniprot id: A0A2U9NDD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2968969:I6G34 RS17540
gene id: 2968969:I6G34_RS17540
uniprot id: A0A2U9N902
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

2968969:I6G34 RS16220
gene id: 2968969:I6G34_RS16220
uniprot id: A0A2U9N9P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

2968969:I6G34 RS01710
gene id: 2968969:I6G34_RS01710
uniprot id: A0A5P9JUV1
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

2968969:I6G34 RS05870
gene id: 2968969:I6G34_RS05870
uniprot id: A0A2U9NFF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

2968969:I6G34 RS10165
gene id: 2968969:I6G34_RS10165
uniprot id: A0A2U9NDB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2968969:I6G34 RS07920
gene id: 2968969:I6G34_RS07920
uniprot id: A0A2U9NH39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

2968969:I6G34 RS16005
gene id: 2968969:I6G34_RS16005
uniprot id: A0A5P9JKR4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

2968969:I6G34 RS16105
gene id: 2968969:I6G34_RS16105
uniprot id: A0A2U9N9R5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2968969:I6G34 RS12155
gene id: 2968969:I6G34_RS12155
uniprot id: A0A5P9JIZ3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

2968969:I6G34 RS11090
gene id: 2968969:I6G34_RS11090
uniprot id: A0A2U9NEX7
names: Subcellular Location Annotation
messages: Cytoplasm

2968969:I6G34 RS19780
gene id: 2968969:I6G34_RS19780
uniprot id: A0A2U9N802
names: Similarity
messages: Belongs to the YfgM family.

2968969:I6G34 RS07140
gene id: 2968969:I6G34_RS07140
uniprot id: A0A2U9NET5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

2968969:I6G34 RS14240
gene id: 2968969:I6G34_RS14240
uniprot id: A0A2U9NDP0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

2968969:I6G34 RS14615
gene id: 2968969:I6G34_RS14615
uniprot id: A0A2U9ND20
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

2968969:I6G34 RS17465
gene id: 2968969:I6G34_RS17465
uniprot id: A0A2U9NB67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

2968969:I6G34 RS08760
gene id: 2968969:I6G34_RS08760
uniprot id: A0A2U9NE58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2968969:I6G34 RS19835
gene id: 2968969:I6G34_RS19835
uniprot id: A0A2U9N7Z2
names: Similarity
messages: Belongs to the HesB/IscA family.

2968969:I6G34 RS14440
gene id: 2968969:I6G34_RS14440
uniprot id: A0A5P9JJN9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

2968969:I6G34 RS02375
gene id: 2968969:I6G34_RS02375
uniprot id: A0A5P9JR03
names: Similarity
messages: Belongs to the globin family.

2968969:I6G34 RS15645
gene id: 2968969:I6G34_RS15645
uniprot id: A0A2U9NCD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2968969:I6G34 RS08790
gene id: 2968969:I6G34_RS08790
uniprot id: A0A2U9NFB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2968969:I6G34 RS08165
gene id: 2968969:I6G34_RS08165
uniprot id: A0A2U9NED8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2968969:I6G34 RS00715
gene id: 2968969:I6G34_RS00715
uniprot id: A0A5P9JUD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2968969:I6G34 RS11860
gene id: 2968969:I6G34_RS11860
uniprot id: A0A2U9NEK6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2968969:I6G34 RS08725
gene id: 2968969:I6G34_RS08725
uniprot id: A0A2U9NGR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2968969:I6G34 RS07215
gene id: 2968969:I6G34_RS07215
uniprot id: A0A2U9NF77
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

2968969:I6G34 RS02480
gene id: 2968969:I6G34_RS02480
uniprot id: A0A2U9N6N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

2968969:I6G34 RS19910
gene id: 2968969:I6G34_RS19910
uniprot id: A0A2U9NA43
names: Subcellular Location Annotation
messages: Membrane

2968969:I6G34 RS08505
gene id: 2968969:I6G34_RS08505
uniprot id: A0A2U9NEA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2968969:I6G34 RS00820
gene id: 2968969:I6G34_RS00820
uniprot id: A0A5P9JQ66
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

2968969:I6G34 RS16615
gene id: 2968969:I6G34_RS16615
uniprot id: A0A5P9JML0
names: Subcellular Location Annotation
messages: Cell inner membrane

2968969:I6G34 RS02660
gene id: 2968969:I6G34_RS02660
uniprot id: A0A5P9JPL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

2968969:I6G34 RS01970
gene id: 2968969:I6G34_RS01970
uniprot id: A0A2U9N6Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

2968969:I6G34 RS11470
gene id: 2968969:I6G34_RS11470
uniprot id: A0A2U9NCJ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2968969:I6G34 RS15425
gene id: 2968969:I6G34_RS15425
uniprot id: A0A2U9NAF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

2968969:I6G34 RS04985
gene id: 2968969:I6G34_RS04985
uniprot id: A0A2U9NG57
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2968969:I6G34 RS10935
gene id: 2968969:I6G34_RS10935
uniprot id: A0A2U9NF58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

2968969:I6G34 RS07180
gene id: 2968969:I6G34_RS07180
uniprot id: A0A2U9NES1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

2968969:I6G34 RS10105
gene id: 2968969:I6G34_RS10105
uniprot id: A0A5P9JI80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

2968969:I6G34 RS01125
gene id: 2968969:I6G34_RS01125
uniprot id: A0A5P9JNP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

2968969:I6G34 RS10360
gene id: 2968969:I6G34_RS10360
uniprot id: A0A2U9NDB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

2968969:I6G34 RS05190
gene id: 2968969:I6G34_RS05190
uniprot id: A0A2U9NFR8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

2968969:I6G34 RS07925
gene id: 2968969:I6G34_RS07925
uniprot id: A0A2U9NED3
names: Similarity
messages: Belongs to the P(II) protein family.

2968969:I6G34 RS08430
gene id: 2968969:I6G34_RS08430
uniprot id: A0A2U9NE46
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

2968969:I6G34 RS14215
gene id: 2968969:I6G34_RS14215
uniprot id: A0A2U9NB25
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

2968969:I6G34 RS16725
gene id: 2968969:I6G34_RS16725
uniprot id: A0A2U9NAQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

2968969:I6G34 RS09895
gene id: 2968969:I6G34_RS09895
uniprot id: A0A5P9JHK3
names: Similarity
messages: Belongs to the peptidase U62 family.

2968969:I6G34 RS14720
gene id: 2968969:I6G34_RS14720
uniprot id: A0A2U9NAS4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2968969:I6G34 RS17295
gene id: 2968969:I6G34_RS17295
uniprot id: A0A5P9JJ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

2968969:I6G34 RS15210
gene id: 2968969:I6G34_RS15210
uniprot id: A0A5P9JLG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

2968969:I6G34 RS08860
gene id: 2968969:I6G34_RS08860
uniprot id: A0A2U9NE30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2968969:I6G34 RS12085
gene id: 2968969:I6G34_RS12085
uniprot id: A0A2U9NC38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

2968969:I6G34 RS02165
gene id: 2968969:I6G34_RS02165
uniprot id: A0A2U9N6V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

2968969:I6G34 RS08740
gene id: 2968969:I6G34_RS08740
uniprot id: A0A2U9NFC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2968969:I6G34 RS07625
gene id: 2968969:I6G34_RS07625
uniprot id: A0A2U9NH97
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

2968969:I6G34 RS15465
gene id: 2968969:I6G34_RS15465
uniprot id: A0A2U9NAA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

2968969:I6G34 RS02710
gene id: 2968969:I6G34_RS02710
uniprot id: A0A2U9N6J8
names: Subcellular Location Annotation
messages: Membrane

2968969:I6G34 RS02310
gene id: 2968969:I6G34_RS02310
uniprot id: A0A2U9N6S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2968969:I6G34 RS10760
gene id: 2968969:I6G34_RS10760
uniprot id: A0A2U9NCW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

2968969:I6G34 RS08545
gene id: 2968969:I6G34_RS08545
uniprot id: A0A2U9NE61
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2968969:I6G34 RS09565
gene id: 2968969:I6G34_RS09565
uniprot id: A0A2U9NDS0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2968969:I6G34 RS15270
gene id: 2968969:I6G34_RS15270
uniprot id: A0A2U9NCK8
names: Subcellular Location Annotation
messages: Membrane

2968969:I6G34 RS10620
gene id: 2968969:I6G34_RS10620
uniprot id: A0A2U9NF92
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

2968969:I6G34 RS09450
gene id: 2968969:I6G34_RS09450
uniprot id: A0A2U9NDL0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

2968969:I6G34 RS15900
gene id: 2968969:I6G34_RS15900
uniprot id: A0A2U9NA74
names: Cofactor
messages: Can also use Mn(2+) ion.

2968969:I6G34 RS15920
gene id: 2968969:I6G34_RS15920
uniprot id: A0A2U9NC78
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

2968969:I6G34 RS06360
gene id: 2968969:I6G34_RS06360
uniprot id: A0A2U9NGG7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

2968969:I6G34 RS10950
gene id: 2968969:I6G34_RS10950
uniprot id: A0A2U9ND13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

2968969:I6G34 RS07980
gene id: 2968969:I6G34_RS07980
uniprot id: A0A2U9NEL0
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

2968969:I6G34 RS11095
gene id: 2968969:I6G34_RS11095
uniprot id: A0A2U9NF09
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2968969:I6G34 RS17480
gene id: 2968969:I6G34_RS17480
uniprot id: A0A2U9N918
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2968969:I6G34 RS09145
gene id: 2968969:I6G34_RS09145
uniprot id: A0A5P9JHM3
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

2968969:I6G34 RS19885
gene id: 2968969:I6G34_RS19885
uniprot id: A0A2U9N828
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

2968969:I6G34 RS08780
gene id: 2968969:I6G34_RS08780
uniprot id: A0A2U9NDY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2968969:I6G34 RS10230
gene id: 2968969:I6G34_RS10230
uniprot id: A0A2U9NFG6
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

2968969:I6G34 RS19790
gene id: 2968969:I6G34_RS19790
uniprot id: A0A2U9NA58
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

2968969:I6G34 RS13585
gene id: 2968969:I6G34_RS13585
uniprot id: A0A5P9JJG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

2968969:I6G34 RS05395
gene id: 2968969:I6G34_RS05395
uniprot id: A0A5P9JEE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

2968969:I6G34 RS08830
gene id: 2968969:I6G34_RS08830
uniprot id: A0A2U9NDY0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2968969:I6G34 RS09855
gene id: 2968969:I6G34_RS09855
uniprot id: A0A2U9NFP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

2968969:I6G34 RS20485
gene id: 2968969:I6G34_RS20485
uniprot id: A0A2U9N7N3
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

2968969:I6G34 RS00320
gene id: 2968969:I6G34_RS00320
uniprot id: A0A2U9NHM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

2968969:I6G34 RS19845
gene id: 2968969:I6G34_RS19845
uniprot id: A0A2U9NA53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

2968969:I6G34 RS07965
gene id: 2968969:I6G34_RS07965
uniprot id: A0A2U9NGU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

2968969:I6G34 RS15795
gene id: 2968969:I6G34_RS15795
uniprot id: A0A5P9JRN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

2968969:I6G34 RS01130
gene id: 2968969:I6G34_RS01130
uniprot id: A0A5P9JLG2
names: Function
names: Subcellular Location Annotation
messages: Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
messages: Periplasm

2968969:I6G34 RS12040
gene id: 2968969:I6G34_RS12040
uniprot id: A0A2U9NC81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2968969:I6G34 RS13705
gene id: 2968969:I6G34_RS13705
uniprot id: A0A5P9JQH1
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

2968969:I6G34 RS19830
gene id: 2968969:I6G34_RS19830
uniprot id: A0A2U9N836
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

2968969:I6G34 RS03400
gene id: 2968969:I6G34_RS03400
uniprot id: A0A5P9JP78
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

2968969:I6G34 RS02250
gene id: 2968969:I6G34_RS02250
uniprot id: A0A2U9N6V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2968969:I6G34 RS09015
gene id: 2968969:I6G34_RS09015
uniprot id: A0A5P9JMP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

2968969:I6G34 RS02105
gene id: 2968969:I6G34_RS02105
uniprot id: A0A2U9N6V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

2968969:I6G34 RS15285
gene id: 2968969:I6G34_RS15285
uniprot id: A0A2U9NAF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

2968969:I6G34 RS02110
gene id: 2968969:I6G34_RS02110
uniprot id: A0A2U9N8Y6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

2968969:I6G34 RS17245
gene id: 2968969:I6G34_RS17245
uniprot id: A0A2U9N969
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

2968969:I6G34 RS08060
gene id: 2968969:I6G34_RS08060
uniprot id: A0A2U9NEQ9
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

2968969:I6G34 RS09930
gene id: 2968969:I6G34_RS09930
uniprot id: A0A2U9NEL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

2968969:I6G34 RS10850
gene id: 2968969:I6G34_RS10850
uniprot id: A0A2U9ND30
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2968969:I6G34 RS17490
gene id: 2968969:I6G34_RS17490
uniprot id: A0A5P9JLL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

2968969:I6G34 RS01905
gene id: 2968969:I6G34_RS01905
uniprot id: A0A2U9N705
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

2968969:I6G34 RS00675
gene id: 2968969:I6G34_RS00675
uniprot id: A0A2U9N7C5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

2968969:I6G34 RS17045
gene id: 2968969:I6G34_RS17045
uniprot id: A0A5P9JJ30
names: Similarity
messages: Belongs to the glutathione peroxidase family.

2968969:I6G34 RS05810
gene id: 2968969:I6G34_RS05810
uniprot id: A0A2U9NHY3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2968969:I6G34 RS18325
gene id: 2968969:I6G34_RS18325
uniprot id: A0A5P9JPT8
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

2968969:I6G34 RS18310
gene id: 2968969:I6G34_RS18310
uniprot id: A0A2U9N8L9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

2968969:I6G34 RS08775
gene id: 2968969:I6G34_RS08775
uniprot id: A0A2U9NGP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2968969:I6G34 RS04910
gene id: 2968969:I6G34_RS04910
uniprot id: A0A2U9NGD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

2968969:I6G34 RS18005
gene id: 2968969:I6G34_RS18005
uniprot id: A0A2U9N8U7
names: Subcellular Location Annotation
messages: Membrane

2968969:I6G34 RS00840
gene id: 2968969:I6G34_RS00840
uniprot id: A0A5P9JR64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

2968969:I6G34 RS16520
gene id: 2968969:I6G34_RS16520
uniprot id: A0A2U9N9K2
names: Similarity
messages: Belongs to the YciI family.

2968969:I6G34 RS10940
gene id: 2968969:I6G34_RS10940
uniprot id: A0A5P9JHV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

2968969:I6G34 RS08670
gene id: 2968969:I6G34_RS08670
uniprot id: A0A2U9NGS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2968969:I6G34 RS08785
gene id: 2968969:I6G34_RS08785
uniprot id: A0A2U9NE77
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2968969:I6G34 RS17610
gene id: 2968969:I6G34_RS17610
uniprot id: A0A5P9JPF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

2968969:I6G34 RS14780
gene id: 2968969:I6G34_RS14780
uniprot id: A0A2U9NHD5
names: Function
names: Similarity
messages: Belongs to the PqqA family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.

2968969:I6G34 RS17530
gene id: 2968969:I6G34_RS17530
uniprot id: A0A2U9N910
names: Similarity
messages: Belongs to the UPF0434 family.

2968969:I6G34 RS00050
gene id: 2968969:I6G34_RS00050
uniprot id: A0A2U9N7N2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2968969:I6G34 RS11885
gene id: 2968969:I6G34_RS11885
uniprot id: A0A2U9NC75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

2968969:I6G34 RS19770
gene id: 2968969:I6G34_RS19770
uniprot id: A0A2U9N814
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

2968969:I6G34 RS20525
gene id: 2968969:I6G34_RS20525
uniprot id: A0A5P9JU09
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

2968969:I6G34 RS00330
gene id: 2968969:I6G34_RS00330
uniprot id: A0A2U9N9X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2968969:I6G34 RS08735
gene id: 2968969:I6G34_RS08735
uniprot id: A0A2U9NGS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2968969:I6G34 RS08865
gene id: 2968969:I6G34_RS08865
uniprot id: A0A2U9NG99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2968969:I6G34 RS08565
gene id: 2968969:I6G34_RS08565
uniprot id: A0A5P9JMG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

2968969:I6G34 RS16225
gene id: 2968969:I6G34_RS16225
uniprot id: A0A2U9N9P9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

2968969:I6G34 RS10185
gene id: 2968969:I6G34_RS10185
uniprot id: A0A2U9NFJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2968969:I6G34 RS08520
gene id: 2968969:I6G34_RS08520
uniprot id: A0A5P9JME4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

2968969:I6G34 RS01370
gene id: 2968969:I6G34_RS01370
uniprot id: A0A2U9N8A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2968969:I6G34 RS17185
gene id: 2968969:I6G34_RS17185
uniprot id: A0A2U9N962
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2968969:I6G34 RS18355
gene id: 2968969:I6G34_RS18355
uniprot id: A0A2U9N8M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2968969:I6G34 RS09025
gene id: 2968969:I6G34_RS09025
uniprot id: A0A2U9NG69
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

2968969:I6G34 RS14630
gene id: 2968969:I6G34_RS14630
uniprot id: A0A2U9NDG7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2968969:I6G34 RS07175
gene id: 2968969:I6G34_RS07175
uniprot id: A0A2U9NHH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

2968969:I6G34 RS08840
gene id: 2968969:I6G34_RS08840
uniprot id: A0A2U9NF98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2968969:I6G34 RS09000
gene id: 2968969:I6G34_RS09000
uniprot id: A0A2U9NF70
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

2968969:I6G34 RS17830
gene id: 2968969:I6G34_RS17830
uniprot id: A0A2U9N8X5
names: Subcellular Location Annotation
messages: Cytoplasm

2968969:I6G34 RS00575
gene id: 2968969:I6G34_RS00575
uniprot id: A0A2U9N7H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2968969:I6G34 RS04920
gene id: 2968969:I6G34_RS04920
uniprot id: A0A2U9NI92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

2968969:I6G34 RS10095
gene id: 2968969:I6G34_RS10095
uniprot id: A0A2U9NEI2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2968969:I6G34 RS04900
gene id: 2968969:I6G34_RS04900
uniprot id: A0A2U9NJ81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2968969:I6G34 RS15830
gene id: 2968969:I6G34_RS15830
uniprot id: A0A2U9NA46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2968969:I6G34 RS08690
gene id: 2968969:I6G34_RS08690
uniprot id: A0A2U9NFD1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.