29552:EXC62 RS00555
gene id: 29552:EXC62_RS00555
uniprot id: A0A449BBF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

29552:EXC62 RS01425
gene id: 29552:EXC62_RS01425
uniprot id: A0A449BBW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

29552:EXC62 RS05625
gene id: 29552:EXC62_RS05625
uniprot id: A0A449BE79
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29552:EXC62 RS06940
gene id: 29552:EXC62_RS06940
uniprot id: A0A449BF18
names: Similarity
messages: Belongs to the ABC transporter superfamily.

29552:EXC62 RS03445
gene id: 29552:EXC62_RS03445
uniprot id: A0A449BD32
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

29552:EXC62 RS02030
gene id: 29552:EXC62_RS02030
uniprot id: A0A449BCA3
names: Similarity
messages: Belongs to the RpoE family.

29552:EXC62 RS06735
gene id: 29552:EXC62_RS06735
uniprot id: A0A449BEY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

29552:EXC62 RS04515
gene id: 29552:EXC62_RS04515
uniprot id: A0A449BDP9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29552:EXC62 RS05195
gene id: 29552:EXC62_RS05195
uniprot id: A0A449BEE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

29552:EXC62 RS07205
gene id: 29552:EXC62_RS07205
uniprot id: A0A449BF33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

29552:EXC62 RS04775
gene id: 29552:EXC62_RS04775
uniprot id: A0A449BDS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

29552:EXC62 RS03235
gene id: 29552:EXC62_RS03235
uniprot id: A0A449BD02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS06690
gene id: 29552:EXC62_RS06690
uniprot id: A0A449BEU1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

29552:EXC62 RS02990
gene id: 29552:EXC62_RS02990
uniprot id: A0A449BCU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

29552:EXC62 RS00190
gene id: 29552:EXC62_RS00190
uniprot id: A0A449BB83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

29552:EXC62 RS06295
gene id: 29552:EXC62_RS06295
uniprot id: A0A449BEP1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

29552:EXC62 RS08375
gene id: 29552:EXC62_RS08375
uniprot id: A0A449BFU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

29552:EXC62 RS02600
gene id: 29552:EXC62_RS02600
uniprot id: A0A449BCK5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

29552:EXC62 RS06595
gene id: 29552:EXC62_RS06595
uniprot id: A0A449BEU9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Cytoplasm
messages: Homotetramer.

29552:EXC62 RS05925
gene id: 29552:EXC62_RS05925
uniprot id: A0A449BED9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

29552:EXC62 RS02400
gene id: 29552:EXC62_RS02400
uniprot id: A0A449BCI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

29552:EXC62 RS02465
gene id: 29552:EXC62_RS02465
uniprot id: A0A449BCJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

29552:EXC62 RS05285
gene id: 29552:EXC62_RS05285
uniprot id: A0A449BE41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

29552:EXC62 RS03115
gene id: 29552:EXC62_RS03115
uniprot id: A0A449BCU4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29552:EXC62 RS06850
gene id: 29552:EXC62_RS06850
uniprot id: A0A449BEX2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

29552:EXC62 RS00625
gene id: 29552:EXC62_RS00625
uniprot id: A0A449BBF7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29552:EXC62 RS02290
gene id: 29552:EXC62_RS02290
uniprot id: A0A449BCF8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

29552:EXC62 RS00475
gene id: 29552:EXC62_RS00475
uniprot id: A0A449BBC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

29552:EXC62 RS06930
gene id: 29552:EXC62_RS06930
uniprot id: A0A449BFD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

29552:EXC62 RS02100
gene id: 29552:EXC62_RS02100
uniprot id: A0A449BCA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

29552:EXC62 RS06440
gene id: 29552:EXC62_RS06440
uniprot id: A0A449BES1
names: Function
names: Similarity
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

29552:EXC62 RS06180
gene id: 29552:EXC62_RS06180
uniprot id: A0A449BEL7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

29552:EXC62 RS04590
gene id: 29552:EXC62_RS04590
uniprot id: A0A449BDQ3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

29552:EXC62 RS05585
gene id: 29552:EXC62_RS05585
uniprot id: A0A449BEA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

29552:EXC62 RS04475
gene id: 29552:EXC62_RS04475
uniprot id: A0A449BDL8
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

29552:EXC62 RS02060
gene id: 29552:EXC62_RS02060
uniprot id: A0A449BC91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

29552:EXC62 RS04855
gene id: 29552:EXC62_RS04855
uniprot id: A0A449BDV4
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

29552:EXC62 RS05190
gene id: 29552:EXC62_RS05190
uniprot id: A0A449BE05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

29552:EXC62 RS02800
gene id: 29552:EXC62_RS02800
uniprot id: A0A449BCR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

29552:EXC62 RS02730
gene id: 29552:EXC62_RS02730
uniprot id: A0A449BCN5
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS05435
gene id: 29552:EXC62_RS05435
uniprot id: A0A449BE71
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

29552:EXC62 RS01525
gene id: 29552:EXC62_RS01525
uniprot id: A0A449BBZ0
names: Similarity
messages: Belongs to the peptidase C15 family.

29552:EXC62 RS00645
gene id: 29552:EXC62_RS00645
uniprot id: A0A449BBV0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29552:EXC62 RS07395
gene id: 29552:EXC62_RS07395
uniprot id: A0A449BF93
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

29552:EXC62 RS06305
gene id: 29552:EXC62_RS06305
uniprot id: A0A449BF22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

29552:EXC62 RS07210
gene id: 29552:EXC62_RS07210
uniprot id: A0A449BF77
names: Similarity
messages: Belongs to the phosphohexose mutase family.

29552:EXC62 RS08285
gene id: 29552:EXC62_RS08285
uniprot id: A0A449BG68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS05250
gene id: 29552:EXC62_RS05250
uniprot id: A0A449BE15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

29552:EXC62 RS00500
gene id: 29552:EXC62_RS00500
uniprot id: A0A449BBS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

29552:EXC62 RS06710
gene id: 29552:EXC62_RS06710
uniprot id: A0A449BEW1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

29552:EXC62 RS03685
gene id: 29552:EXC62_RS03685
uniprot id: A0A449BD69
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

29552:EXC62 RS03290
gene id: 29552:EXC62_RS03290
uniprot id: A0A449BD05
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

29552:EXC62 RS00485
gene id: 29552:EXC62_RS00485
uniprot id: A0A449BBC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

29552:EXC62 RS02940
gene id: 29552:EXC62_RS02940
uniprot id: A0A449BCT1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

29552:EXC62 RS02125
gene id: 29552:EXC62_RS02125
uniprot id: A0A449BCB0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

29552:EXC62 RS07215
gene id: 29552:EXC62_RS07215
uniprot id: A0A449BF61
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

29552:EXC62 RS02000
gene id: 29552:EXC62_RS02000
uniprot id: A0A449BC84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

29552:EXC62 RS04400
gene id: 29552:EXC62_RS04400
uniprot id: A0A449BDJ4
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS02205
gene id: 29552:EXC62_RS02205
uniprot id: A0A449BCN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

29552:EXC62 RS05750
gene id: 29552:EXC62_RS05750
uniprot id: A0A449BEA9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

29552:EXC62 RS02765
gene id: 29552:EXC62_RS02765
uniprot id: A0A449BCN1
names: Similarity
messages: Belongs to the peptidase S1C family.

29552:EXC62 RS07105
gene id: 29552:EXC62_RS07105
uniprot id: A0A449BF53
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS02250
gene id: 29552:EXC62_RS02250
uniprot id: A0A449BCD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

29552:EXC62 RS07855
gene id: 29552:EXC62_RS07855
uniprot id: A0A449BFI7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

29552:EXC62 RS08470
gene id: 29552:EXC62_RS08470
uniprot id: A0A449BFT8
names: Similarity
messages: Belongs to the SecB family.

29552:EXC62 RS02415
gene id: 29552:EXC62_RS02415
uniprot id: A0A449BCG6
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

29552:EXC62 RS07465
gene id: 29552:EXC62_RS07465
uniprot id: A0A449BF99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS01420
gene id: 29552:EXC62_RS01420
uniprot id: A0A449BBX1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

29552:EXC62 RS01940
gene id: 29552:EXC62_RS01940
uniprot id: A0A449BC82
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

29552:EXC62 RS02055
gene id: 29552:EXC62_RS02055
uniprot id: A0A449BCL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

29552:EXC62 RS07770
gene id: 29552:EXC62_RS07770
uniprot id: A0A449BFG0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

29552:EXC62 RS03250
gene id: 29552:EXC62_RS03250
uniprot id: A0A449BDB9
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS04875
gene id: 29552:EXC62_RS04875
uniprot id: A0A449BDU4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

29552:EXC62 RS04865
gene id: 29552:EXC62_RS04865
uniprot id: A0A449BDS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

29552:EXC62 RS07735
gene id: 29552:EXC62_RS07735
uniprot id: A0A449BFE8
names: Subcellular Location Annotation
messages: Cytoplasm

29552:EXC62 RS04170
gene id: 29552:EXC62_RS04170
uniprot id: A0A449BDE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

29552:EXC62 RS05110
gene id: 29552:EXC62_RS05110
uniprot id: A0A449BDY1
names: Similarity
messages: Belongs to the UPF0473 family.

29552:EXC62 RS08430
gene id: 29552:EXC62_RS08430
uniprot id: A0A449BFT6
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

29552:EXC62 RS05955
gene id: 29552:EXC62_RS05955
uniprot id: A0A449BEU8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29552:EXC62 RS00895
gene id: 29552:EXC62_RS00895
uniprot id: A0A449BBZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS05495
gene id: 29552:EXC62_RS05495
uniprot id: A0A449BE63
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

29552:EXC62 RS02230
gene id: 29552:EXC62_RS02230
uniprot id: A0A449BCE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

29552:EXC62 RS02195
gene id: 29552:EXC62_RS02195
uniprot id: A0A449BCD8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

29552:EXC62 RS00285
gene id: 29552:EXC62_RS00285
uniprot id: A0A449BBA1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

29552:EXC62 RS05940
gene id: 29552:EXC62_RS05940
uniprot id: A0A449BEG5
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.

29552:EXC62 RS07995
gene id: 29552:EXC62_RS07995
uniprot id: A0A449BFK0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

29552:EXC62 RS02740
gene id: 29552:EXC62_RS02740
uniprot id: A0A449BCP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

29552:EXC62 RS02640
gene id: 29552:EXC62_RS02640
uniprot id: A0A449BCN7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

29552:EXC62 RS08070
gene id: 29552:EXC62_RS08070
uniprot id: A0A449BFM2
names: Similarity
messages: Belongs to the peptidase S51 family.

29552:EXC62 RS05565
gene id: 29552:EXC62_RS05565
uniprot id: A0A449BEA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

29552:EXC62 RS00395
gene id: 29552:EXC62_RS00395
uniprot id: A0A449BBQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

29552:EXC62 RS02120
gene id: 29552:EXC62_RS02120
uniprot id: A0A449BCB2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

29552:EXC62 RS08245
gene id: 29552:EXC62_RS08245
uniprot id: A0A449BFQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

29552:EXC62 RS08120
gene id: 29552:EXC62_RS08120
uniprot id: A0A449BFR7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

29552:EXC62 RS00400
gene id: 29552:EXC62_RS00400
uniprot id: A0A449BBA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

29552:EXC62 RS04525
gene id: 29552:EXC62_RS04525
uniprot id: A0A449BDM7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29552:EXC62 RS05260
gene id: 29552:EXC62_RS05260
uniprot id: A0A449BE09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

29552:EXC62 RS00735
gene id: 29552:EXC62_RS00735
uniprot id: A0A449BBI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS08305
gene id: 29552:EXC62_RS08305
uniprot id: A0A449BFR5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

29552:EXC62 RS04145
gene id: 29552:EXC62_RS04145
uniprot id: A0A449BDF3
names: Similarity
messages: Belongs to the CvfB family.

29552:EXC62 RS05560
gene id: 29552:EXC62_RS05560
uniprot id: A0A449BE72
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

29552:EXC62 RS02185
gene id: 29552:EXC62_RS02185
uniprot id: A0A449BCD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

29552:EXC62 RS02405
gene id: 29552:EXC62_RS02405
uniprot id: A0A449BCG7
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS05840
gene id: 29552:EXC62_RS05840
uniprot id: A0A449BEE5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

29552:EXC62 RS04350
gene id: 29552:EXC62_RS04350
uniprot id: A0A449BDJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

29552:EXC62 RS07850
gene id: 29552:EXC62_RS07850
uniprot id: A0A449BFX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

29552:EXC62 RS06275
gene id: 29552:EXC62_RS06275
uniprot id: A0A449BEL2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

29552:EXC62 RS05135
gene id: 29552:EXC62_RS05135
uniprot id: A0A449BE11
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

29552:EXC62 RS06715
gene id: 29552:EXC62_RS06715
uniprot id: A0A449BEW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

29552:EXC62 RS04330
gene id: 29552:EXC62_RS04330
uniprot id: A0A449BDK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

29552:EXC62 RS01045
gene id: 29552:EXC62_RS01045
uniprot id: A0A449BBQ8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

29552:EXC62 RS05880
gene id: 29552:EXC62_RS05880
uniprot id: A0A449BEG1
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

29552:EXC62 RS07470
gene id: 29552:EXC62_RS07470
uniprot id: A0A449BFC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS06230
gene id: 29552:EXC62_RS06230
uniprot id: A0A449BEM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29552:EXC62 RS05705
gene id: 29552:EXC62_RS05705
uniprot id: A0A449BEA3
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS01445
gene id: 29552:EXC62_RS01445
uniprot id: A0A449BBY8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

29552:EXC62 RS03455
gene id: 29552:EXC62_RS03455
uniprot id: A0A449BDF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

29552:EXC62 RS06300
gene id: 29552:EXC62_RS06300
uniprot id: A0A449BEM3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

29552:EXC62 RS02550
gene id: 29552:EXC62_RS02550
uniprot id: A0A449BCJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

29552:EXC62 RS03760
gene id: 29552:EXC62_RS03760
uniprot id: A0A449BD61
names: Similarity
messages: Belongs to the IMPACT family.

29552:EXC62 RS02790
gene id: 29552:EXC62_RS02790
uniprot id: A0A449BCQ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

29552:EXC62 RS04985
gene id: 29552:EXC62_RS04985
uniprot id: A0A449BDY2
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS07725
gene id: 29552:EXC62_RS07725
uniprot id: A0A449BFH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29552:EXC62 RS05660
gene id: 29552:EXC62_RS05660
uniprot id: A0A449BEB9
names: Similarity
messages: Belongs to the asparaginase 1 family.

29552:EXC62 RS00385
gene id: 29552:EXC62_RS00385
uniprot id: A0A449BBB7
names: Similarity
messages: Belongs to the ParB family.

29552:EXC62 RS03160
gene id: 29552:EXC62_RS03160
uniprot id: A0A449BCY5
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

29552:EXC62 RS01415
gene id: 29552:EXC62_RS01415
uniprot id: A0A449BBY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

29552:EXC62 RS03145
gene id: 29552:EXC62_RS03145
uniprot id: A0A449BCX8
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

29552:EXC62 RS04035
gene id: 29552:EXC62_RS04035
uniprot id: A0A449BDF1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

29552:EXC62 RS04580
gene id: 29552:EXC62_RS04580
uniprot id: A0A449BE26
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS04135
gene id: 29552:EXC62_RS04135
uniprot id: A0A449BDE4
names: Subcellular Location Annotation
messages: Cytoplasm

29552:EXC62 RS01015
gene id: 29552:EXC62_RS01015
uniprot id: A0A449BBP4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

29552:EXC62 RS06865
gene id: 29552:EXC62_RS06865
uniprot id: A0A449BEY8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

29552:EXC62 RS03620
gene id: 29552:EXC62_RS03620
uniprot id: A0A449BD44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

29552:EXC62 RS02155
gene id: 29552:EXC62_RS02155
uniprot id: A0A449BCN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

29552:EXC62 RS01220
gene id: 29552:EXC62_RS01220
uniprot id: A0A449BBT5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

29552:EXC62 RS03260
gene id: 29552:EXC62_RS03260
uniprot id: A0A449BD07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS06310
gene id: 29552:EXC62_RS06310
uniprot id: A0A449BEM4
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

29552:EXC62 RS04025
gene id: 29552:EXC62_RS04025
uniprot id: A0A449BDB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

29552:EXC62 RS01010
gene id: 29552:EXC62_RS01010
uniprot id: A0A449BBN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
messages: Cell membrane
messages: Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.
messages: The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

29552:EXC62 RS01215
gene id: 29552:EXC62_RS01215
uniprot id: A0A449BBS5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

29552:EXC62 RS05235
gene id: 29552:EXC62_RS05235
uniprot id: A0A449BE31
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

29552:EXC62 RS05080
gene id: 29552:EXC62_RS05080
uniprot id: A0A449BE03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

29552:EXC62 RS06775
gene id: 29552:EXC62_RS06775
uniprot id: A0A449BFA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

29552:EXC62 RS06075
gene id: 29552:EXC62_RS06075
uniprot id: A0A449BEH1
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

29552:EXC62 RS00560
gene id: 29552:EXC62_RS00560
uniprot id: A0A449BBE3
names: Similarity
messages: Belongs to the DtxR/MntR family.

29552:EXC62 RS07680
gene id: 29552:EXC62_RS07680
uniprot id: A0A449BFF1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

29552:EXC62 RS06915
gene id: 29552:EXC62_RS06915
uniprot id: A0A449BEZ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

29552:EXC62 RS07970
gene id: 29552:EXC62_RS07970
uniprot id: A0A449BFK6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

29552:EXC62 RS07460
gene id: 29552:EXC62_RS07460
uniprot id: A0A449BFB0
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

29552:EXC62 RS04150
gene id: 29552:EXC62_RS04150
uniprot id: A0A449BDH7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

29552:EXC62 RS05525
gene id: 29552:EXC62_RS05525
uniprot id: A0A449BE60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

29552:EXC62 RS08985
gene id: 29552:EXC62_RS08985
uniprot id: A0A449BF85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS07035
gene id: 29552:EXC62_RS07035
uniprot id: A0A449BF20
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

29552:EXC62 RS07625
gene id: 29552:EXC62_RS07625
uniprot id: A0A449BFF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29552:EXC62 RS02690
gene id: 29552:EXC62_RS02690
uniprot id: A0A449BCM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

29552:EXC62 RS07715
gene id: 29552:EXC62_RS07715
uniprot id: A0A449BFE7
names: Similarity
messages: Belongs to the ArsC family.

29552:EXC62 RS03475
gene id: 29552:EXC62_RS03475
uniprot id: A0A449BD15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

29552:EXC62 RS02840
gene id: 29552:EXC62_RS02840
uniprot id: A0A449BCR2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

29552:EXC62 RS03900
gene id: 29552:EXC62_RS03900
uniprot id: A0A449BDQ2
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS02815
gene id: 29552:EXC62_RS02815
uniprot id: A0A449BCP7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

29552:EXC62 RS05405
gene id: 29552:EXC62_RS05405
uniprot id: A0A449BE65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS04530
gene id: 29552:EXC62_RS04530
uniprot id: A0A449BE14
names: Similarity
messages: Belongs to the peptidase M29 family.

29552:EXC62 RS01410
gene id: 29552:EXC62_RS01410
uniprot id: A0A449BBW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

29552:EXC62 RS00205
gene id: 29552:EXC62_RS00205
uniprot id: A0A449BB98
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

29552:EXC62 RS02950
gene id: 29552:EXC62_RS02950
uniprot id: A0A449BCU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

29552:EXC62 RS04220
gene id: 29552:EXC62_RS04220
uniprot id: A0A449BDF5
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

29552:EXC62 RS03110
gene id: 29552:EXC62_RS03110
uniprot id: A0A449BCX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

29552:EXC62 RS03310
gene id: 29552:EXC62_RS03310
uniprot id: A0A449BD17
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

29552:EXC62 RS03180
gene id: 29552:EXC62_RS03180
uniprot id: A0A449BCX1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

29552:EXC62 RS03470
gene id: 29552:EXC62_RS03470
uniprot id: A0A449BD13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

29552:EXC62 RS05345
gene id: 29552:EXC62_RS05345
uniprot id: A0A449BEH7
names: Function
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

29552:EXC62 RS05240
gene id: 29552:EXC62_RS05240
uniprot id: A0A449BE17
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

29552:EXC62 RS07575
gene id: 29552:EXC62_RS07575
uniprot id: A0A449BFE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

29552:EXC62 RS05595
gene id: 29552:EXC62_RS05595
uniprot id: A0A449BEA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

29552:EXC62 RS05610
gene id: 29552:EXC62_RS05610
uniprot id: A0A449BE83
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

29552:EXC62 RS08390
gene id: 29552:EXC62_RS08390
uniprot id: A0A449BFU4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

29552:EXC62 RS03630
gene id: 29552:EXC62_RS03630
uniprot id: A0A449BD68
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

29552:EXC62 RS00150
gene id: 29552:EXC62_RS00150
uniprot id: A0A449BB80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

29552:EXC62 RS07145
gene id: 29552:EXC62_RS07145
uniprot id: A0A449BF49
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS03510
gene id: 29552:EXC62_RS03510
uniprot id: A0A449BD10
names: Similarity
messages: Belongs to the chorismate synthase family.

29552:EXC62 RS03240
gene id: 29552:EXC62_RS03240
uniprot id: A0A449BCZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS07535
gene id: 29552:EXC62_RS07535
uniprot id: A0A449BFC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

29552:EXC62 RS04125
gene id: 29552:EXC62_RS04125
uniprot id: A0A449BDD8
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS02570
gene id: 29552:EXC62_RS02570
uniprot id: A0A449BCK4
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

29552:EXC62 RS05225
gene id: 29552:EXC62_RS05225
uniprot id: A0A449BE22
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

29552:EXC62 RS00155
gene id: 29552:EXC62_RS00155
uniprot id: A0A449BB88
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

29552:EXC62 RS01600
gene id: 29552:EXC62_RS01600
uniprot id: A0A449BCD1
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

29552:EXC62 RS07705
gene id: 29552:EXC62_RS07705
uniprot id: A0A449BFF6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

29552:EXC62 RS07080
gene id: 29552:EXC62_RS07080
uniprot id: A0A449BFG3
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS02705
gene id: 29552:EXC62_RS02705
uniprot id: A0A449BCM5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

29552:EXC62 RS04160
gene id: 29552:EXC62_RS04160
uniprot id: A0A449BDG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

29552:EXC62 RS03420
gene id: 29552:EXC62_RS03420
uniprot id: A0A449BCZ9
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

29552:EXC62 RS02435
gene id: 29552:EXC62_RS02435
uniprot id: A0A449BCI6
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

29552:EXC62 RS00580
gene id: 29552:EXC62_RS00580
uniprot id: A0A449BBE9
names: Similarity
messages: Belongs to the BMP lipoprotein family.

29552:EXC62 RS04180
gene id: 29552:EXC62_RS04180
uniprot id: A0A449BDE6
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS00550
gene id: 29552:EXC62_RS00550
uniprot id: A0A449BBD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

29552:EXC62 RS02745
gene id: 29552:EXC62_RS02745
uniprot id: A0A449BCQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

29552:EXC62 RS02170
gene id: 29552:EXC62_RS02170
uniprot id: A0A449BCC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

29552:EXC62 RS00290
gene id: 29552:EXC62_RS00290
uniprot id: A0A449BBA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

29552:EXC62 RS05205
gene id: 29552:EXC62_RS05205
uniprot id: A0A449BE24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

29552:EXC62 RS07430
gene id: 29552:EXC62_RS07430
uniprot id: A0A449BFN4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

29552:EXC62 RS01920
gene id: 29552:EXC62_RS01920
uniprot id: A0A449BC77
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

29552:EXC62 RS05185
gene id: 29552:EXC62_RS05185
uniprot id: A0A449BE21
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

29552:EXC62 RS07935
gene id: 29552:EXC62_RS07935
uniprot id: A0A449BFI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS01785
gene id: 29552:EXC62_RS01785
uniprot id: A0A449BC49
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS05820
gene id: 29552:EXC62_RS05820
uniprot id: A0A449BEB8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

29552:EXC62 RS02285
gene id: 29552:EXC62_RS02285
uniprot id: A0A449BCF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

29552:EXC62 RS05780
gene id: 29552:EXC62_RS05780
uniprot id: A0A449BED8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

29552:EXC62 RS04275
gene id: 29552:EXC62_RS04275
uniprot id: A0A449BDG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

29552:EXC62 RS02160
gene id: 29552:EXC62_RS02160
uniprot id: A0A449BCB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

29552:EXC62 RS03680
gene id: 29552:EXC62_RS03680
uniprot id: A0A449BD77
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS07540
gene id: 29552:EXC62_RS07540
uniprot id: A0A449BFC5
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

29552:EXC62 RS04195
gene id: 29552:EXC62_RS04195
uniprot id: A0A449BDG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

29552:EXC62 RS02885
gene id: 29552:EXC62_RS02885
uniprot id: A0A449BCT0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

29552:EXC62 RS02150
gene id: 29552:EXC62_RS02150
uniprot id: A0A449BCB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

29552:EXC62 RS05905
gene id: 29552:EXC62_RS05905
uniprot id: A0A449BET7
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

29552:EXC62 RS01535
gene id: 29552:EXC62_RS01535
uniprot id: A0A449BC02
names: Similarity
messages: Belongs to the ABC transporter superfamily.

29552:EXC62 RS05540
gene id: 29552:EXC62_RS05540
uniprot id: A0A449BE90
names: Similarity
messages: Belongs to the UPF0758 family.

29552:EXC62 RS00450
gene id: 29552:EXC62_RS00450
uniprot id: A0A449BBR0
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS07270
gene id: 29552:EXC62_RS07270
uniprot id: A0A449BF60
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

29552:EXC62 RS06225
gene id: 29552:EXC62_RS06225
uniprot id: A0A449BEK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

29552:EXC62 RS07750
gene id: 29552:EXC62_RS07750
uniprot id: A0A449BFV2
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS00505
gene id: 29552:EXC62_RS00505
uniprot id: A0A449BBB9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

29552:EXC62 RS03690
gene id: 29552:EXC62_RS03690
uniprot id: A0A449BD87
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

29552:EXC62 RS02755
gene id: 29552:EXC62_RS02755
uniprot id: A0A449BCN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

29552:EXC62 RS04055
gene id: 29552:EXC62_RS04055
uniprot id: A0A449BDS6
names: Similarity
messages: Belongs to the peptidase C1 family.

29552:EXC62 RS03575
gene id: 29552:EXC62_RS03575
uniprot id: A0A449BD31
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

29552:EXC62 RS07375
gene id: 29552:EXC62_RS07375
uniprot id: A0A449BFA3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

29552:EXC62 RS06790
gene id: 29552:EXC62_RS06790
uniprot id: A0A449BEV7
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS06730
gene id: 29552:EXC62_RS06730
uniprot id: A0A449BEV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

29552:EXC62 RS02995
gene id: 29552:EXC62_RS02995
uniprot id: A0A449BCW6
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.

29552:EXC62 RS05765
gene id: 29552:EXC62_RS05765
uniprot id: A0A449BEE2
names: Similarity
messages: Belongs to the thioredoxin family.

29552:EXC62 RS05785
gene id: 29552:EXC62_RS05785
uniprot id: A0A449BED6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

29552:EXC62 RS05545
gene id: 29552:EXC62_RS05545
uniprot id: A0A449BE96
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS06935
gene id: 29552:EXC62_RS06935
uniprot id: A0A449BEZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29552:EXC62 RS05245
gene id: 29552:EXC62_RS05245
uniprot id: A0A449BEF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

29552:EXC62 RS07585
gene id: 29552:EXC62_RS07585
uniprot id: A0A449BFR6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

29552:EXC62 RS00405
gene id: 29552:EXC62_RS00405
uniprot id: A0A449BBC8
names: Similarity
messages: Belongs to the transketolase family.

29552:EXC62 RS00655
gene id: 29552:EXC62_RS00655
uniprot id: A0A449BBH6
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

29552:EXC62 RS02615
gene id: 29552:EXC62_RS02615
uniprot id: A0A449BCL9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

29552:EXC62 RS05605
gene id: 29552:EXC62_RS05605
uniprot id: A0A449BEM5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29552:EXC62 RS06830
gene id: 29552:EXC62_RS06830
uniprot id: A0A449BFB2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

29552:EXC62 RS00275
gene id: 29552:EXC62_RS00275
uniprot id: A0A449BBB8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

29552:EXC62 RS04090
gene id: 29552:EXC62_RS04090
uniprot id: A0A449BDG6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

29552:EXC62 RS02220
gene id: 29552:EXC62_RS02220
uniprot id: A0A449BCD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

29552:EXC62 RS00165
gene id: 29552:EXC62_RS00165
uniprot id: A0A449BBM5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

29552:EXC62 RS07800
gene id: 29552:EXC62_RS07800
uniprot id: A0A449BFH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

29552:EXC62 RS00125
gene id: 29552:EXC62_RS00125
uniprot id: A0A449BB85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

29552:EXC62 RS04200
gene id: 29552:EXC62_RS04200
uniprot id: A0A449BDJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

29552:EXC62 RS00585
gene id: 29552:EXC62_RS00585
uniprot id: A0A449BBF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

29552:EXC62 RS08370
gene id: 29552:EXC62_RS08370
uniprot id: A0A449BFR8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29552:EXC62 RS02545
gene id: 29552:EXC62_RS02545
uniprot id: A0A449BCL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

29552:EXC62 RS05590
gene id: 29552:EXC62_RS05590
uniprot id: A0A449BE98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

29552:EXC62 RS00815
gene id: 29552:EXC62_RS00815
uniprot id: A0A449BBH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

29552:EXC62 RS03010
gene id: 29552:EXC62_RS03010
uniprot id: A0A449BD76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

29552:EXC62 RS02225
gene id: 29552:EXC62_RS02225
uniprot id: A0A449BCD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

29552:EXC62 RS04320
gene id: 29552:EXC62_RS04320
uniprot id: A0A449BDX6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29552:EXC62 RS05390
gene id: 29552:EXC62_RS05390
uniprot id: A0A449BE42
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS07835
gene id: 29552:EXC62_RS07835
uniprot id: A0A449BFG6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

29552:EXC62 RS07815
gene id: 29552:EXC62_RS07815
uniprot id: A0A449BFH4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

29552:EXC62 RS00570
gene id: 29552:EXC62_RS00570
uniprot id: A0A449BBE1
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS06975
gene id: 29552:EXC62_RS06975
uniprot id: A0A449BF01
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

29552:EXC62 RS07165
gene id: 29552:EXC62_RS07165
uniprot id: A0A449BF51
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

29552:EXC62 RS05665
gene id: 29552:EXC62_RS05665
uniprot id: A0A449BE89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

29552:EXC62 RS00535
gene id: 29552:EXC62_RS00535
uniprot id: A0A449BBE6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

29552:EXC62 RS01760
gene id: 29552:EXC62_RS01760
uniprot id: A0A449BC58
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

29552:EXC62 RS01040
gene id: 29552:EXC62_RS01040
uniprot id: A0A449BBN3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

29552:EXC62 RS05160
gene id: 29552:EXC62_RS05160
uniprot id: A0A449BDZ1
names: Similarity
messages: Belongs to the Iojap/RsfS family.

29552:EXC62 RS02040
gene id: 29552:EXC62_RS02040
uniprot id: A0A449BCA6
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

29552:EXC62 RS01950
gene id: 29552:EXC62_RS01950
uniprot id: A0A449BC76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS06165
gene id: 29552:EXC62_RS06165
uniprot id: A0A449BEM1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

29552:EXC62 RS07990
gene id: 29552:EXC62_RS07990
uniprot id: A0A449BFM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

29552:EXC62 RS00495
gene id: 29552:EXC62_RS00495
uniprot id: A0A449BBD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

29552:EXC62 RS02215
gene id: 29552:EXC62_RS02215
uniprot id: A0A449BCE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

29552:EXC62 RS07060
gene id: 29552:EXC62_RS07060
uniprot id: A0A449BF34
names: Similarity
messages: Belongs to the ABC transporter superfamily.

29552:EXC62 RS04270
gene id: 29552:EXC62_RS04270
uniprot id: A0A449BDW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

29552:EXC62 RS02485
gene id: 29552:EXC62_RS02485
uniprot id: A0A449BCJ1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29552:EXC62 RS00220
gene id: 29552:EXC62_RS00220
uniprot id: A0A449BB86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

29552:EXC62 RS04345
gene id: 29552:EXC62_RS04345
uniprot id: A0A449BDK5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29552:EXC62 RS05380
gene id: 29552:EXC62_RS05380
uniprot id: A0A449BE62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS00180
gene id: 29552:EXC62_RS00180
uniprot id: A0A449BB81
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

29552:EXC62 RS05865
gene id: 29552:EXC62_RS05865
uniprot id: A0A449BEG2
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

29552:EXC62 RS03105
gene id: 29552:EXC62_RS03105
uniprot id: A0A449BCT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS04225
gene id: 29552:EXC62_RS04225
uniprot id: A0A449BDI6
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

29552:EXC62 RS07040
gene id: 29552:EXC62_RS07040
uniprot id: A0A449BF37
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS08105
gene id: 29552:EXC62_RS08105
uniprot id: A0A449BFM6
names: Similarity
messages: Belongs to the peptidase S66 family.

29552:EXC62 RS02240
gene id: 29552:EXC62_RS02240
uniprot id: A0A449BCE5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

29552:EXC62 RS07355
gene id: 29552:EXC62_RS07355
uniprot id: A0A449BF73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS01955
gene id: 29552:EXC62_RS01955
uniprot id: A0A449BCI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS02235
gene id: 29552:EXC62_RS02235
uniprot id: A0A449BCE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

29552:EXC62 RS06215
gene id: 29552:EXC62_RS06215
uniprot id: A0A449BEN1
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

29552:EXC62 RS07915
gene id: 29552:EXC62_RS07915
uniprot id: A0A449BFI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS04255
gene id: 29552:EXC62_RS04255
uniprot id: A0A449BDK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

29552:EXC62 RS08410
gene id: 29552:EXC62_RS08410
uniprot id: A0A449BFY1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

29552:EXC62 RS00995
gene id: 29552:EXC62_RS00995
uniprot id: A0A449BBM2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

29552:EXC62 RS02085
gene id: 29552:EXC62_RS02085
uniprot id: A0A449BCB4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

29552:EXC62 RS06970
gene id: 29552:EXC62_RS06970
uniprot id: A0A449BF26
names: Similarity
messages: Belongs to the ABC transporter superfamily.

29552:EXC62 RS02390
gene id: 29552:EXC62_RS02390
uniprot id: A0A449BCH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

29552:EXC62 RS02980
gene id: 29552:EXC62_RS02980
uniprot id: A0A449BCT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

29552:EXC62 RS05800
gene id: 29552:EXC62_RS05800
uniprot id: A0A449BEC1
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

29552:EXC62 RS02595
gene id: 29552:EXC62_RS02595
uniprot id: A0A449BCM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

29552:EXC62 RS03655
gene id: 29552:EXC62_RS03655
uniprot id: A0A449BDK1
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS05550
gene id: 29552:EXC62_RS05550
uniprot id: A0A449BE73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

29552:EXC62 RS04355
gene id: 29552:EXC62_RS04355
uniprot id: A0A449BDL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

29552:EXC62 RS03410
gene id: 29552:EXC62_RS03410
uniprot id: A0A449BCZ1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

29552:EXC62 RS00515
gene id: 29552:EXC62_RS00515
uniprot id: A0A449BBB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

29552:EXC62 RS03695
gene id: 29552:EXC62_RS03695
uniprot id: A0A449BD83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

29552:EXC62 RS02985
gene id: 29552:EXC62_RS02985
uniprot id: A0A449BCV2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29552:EXC62 RS07185
gene id: 29552:EXC62_RS07185
uniprot id: A0A449BFI6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

29552:EXC62 RS02920
gene id: 29552:EXC62_RS02920
uniprot id: A0A449BCT9
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

29552:EXC62 RS08035
gene id: 29552:EXC62_RS08035
uniprot id: A0A449BFK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

29552:EXC62 RS06745
gene id: 29552:EXC62_RS06745
uniprot id: A0A449BEV1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

29552:EXC62 RS05280
gene id: 29552:EXC62_RS05280
uniprot id: A0A449BE44
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

29552:EXC62 RS02035
gene id: 29552:EXC62_RS02035
uniprot id: A0A449BCA7
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29552:EXC62 RS02805
gene id: 29552:EXC62_RS02805
uniprot id: A0A449BCP8
names: Similarity
messages: Belongs to the peptidase M13 family.

29552:EXC62 RS05630
gene id: 29552:EXC62_RS05630
uniprot id: A0A449BEA4
names: Similarity
messages: Belongs to the peptidase M24B family.

29552:EXC62 RS02005
gene id: 29552:EXC62_RS02005
uniprot id: A0A449BCJ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29552:EXC62 RS02430
gene id: 29552:EXC62_RS02430
uniprot id: A0A449BCH0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

29552:EXC62 RS02520
gene id: 29552:EXC62_RS02520
uniprot id: A0A449BCJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

29552:EXC62 RS05945
gene id: 29552:EXC62_RS05945
uniprot id: A0A449BEH3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

29552:EXC62 RS03745
gene id: 29552:EXC62_RS03745
uniprot id: A0A449BD95
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29552:EXC62 RS06955
gene id: 29552:EXC62_RS06955
uniprot id: A0A449BF27
names: Similarity
messages: Belongs to the peptidase U62 family.

29552:EXC62 RS07125
gene id: 29552:EXC62_RS07125
uniprot id: A0A449BF29
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS03550
gene id: 29552:EXC62_RS03550
uniprot id: A0A449BD27
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

29552:EXC62 RS00565
gene id: 29552:EXC62_RS00565
uniprot id: A0A449BBC7
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS06110
gene id: 29552:EXC62_RS06110
uniprot id: A0A449BEX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

29552:EXC62 RS01450
gene id: 29552:EXC62_RS01450
uniprot id: A0A449BBY4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

29552:EXC62 RS05515
gene id: 29552:EXC62_RS05515
uniprot id: A0A449BE87
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

29552:EXC62 RS05075
gene id: 29552:EXC62_RS05075
uniprot id: A0A449BDY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

29552:EXC62 RS02015
gene id: 29552:EXC62_RS02015
uniprot id: A0A449BCA4
names: Caution
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

29552:EXC62 RS07930
gene id: 29552:EXC62_RS07930
uniprot id: A0A449BFK5
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS06835
gene id: 29552:EXC62_RS06835
uniprot id: A0A449BEX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

29552:EXC62 RS05255
gene id: 29552:EXC62_RS05255
uniprot id: A0A449BE34
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

29552:EXC62 RS07405
gene id: 29552:EXC62_RS07405
uniprot id: A0A449BF83
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

29552:EXC62 RS06845
gene id: 29552:EXC62_RS06845
uniprot id: A0A449BEW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

29552:EXC62 RS02180
gene id: 29552:EXC62_RS02180
uniprot id: A0A449BCD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

29552:EXC62 RS00215
gene id: 29552:EXC62_RS00215
uniprot id: A0A449BBN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

29552:EXC62 RS02525
gene id: 29552:EXC62_RS02525
uniprot id: A0A449BCJ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29552:EXC62 RS01385
gene id: 29552:EXC62_RS01385
uniprot id: A0A449BBX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

29552:EXC62 RS00705
gene id: 29552:EXC62_RS00705
uniprot id: A0A449BBI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS08265
gene id: 29552:EXC62_RS08265
uniprot id: A0A449BFT2
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

29552:EXC62 RS01915
gene id: 29552:EXC62_RS01915
uniprot id: A0A449BC87
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS01315
gene id: 29552:EXC62_RS01315
uniprot id: A0A449BBW9
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS02210
gene id: 29552:EXC62_RS02210
uniprot id: A0A449BCC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

29552:EXC62 RS01660
gene id: 29552:EXC62_RS01660
uniprot id: A0A449BC37
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29552:EXC62 RS05805
gene id: 29552:EXC62_RS05805
uniprot id: A0A449BER3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29552:EXC62 RS07055
gene id: 29552:EXC62_RS07055
uniprot id: A0A449BF45
names: Similarity
messages: Belongs to the ABC transporter superfamily.

29552:EXC62 RS08425
gene id: 29552:EXC62_RS08425
uniprot id: A0A449BFV7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

29552:EXC62 RS01530
gene id: 29552:EXC62_RS01530
uniprot id: A0A449BBZ8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

29552:EXC62 RS07160
gene id: 29552:EXC62_RS07160
uniprot id: A0A449BF66
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS07190
gene id: 29552:EXC62_RS07190
uniprot id: A0A449BF57
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29552:EXC62 RS08260
gene id: 29552:EXC62_RS08260
uniprot id: A0A449BFU7
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

29552:EXC62 RS04410
gene id: 29552:EXC62_RS04410
uniprot id: A0A449BDK2
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

29552:EXC62 RS05270
gene id: 29552:EXC62_RS05270
uniprot id: A0A449BE38
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

29552:EXC62 RS00510
gene id: 29552:EXC62_RS00510
uniprot id: A0A449BBD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

29552:EXC62 RS05005
gene id: 29552:EXC62_RS05005
uniprot id: A0A449BDY4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

29552:EXC62 RS03530
gene id: 29552:EXC62_RS03530
uniprot id: A0A449BD47
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

29552:EXC62 RS06720
gene id: 29552:EXC62_RS06720
uniprot id: A0A449BEV2
names: Similarity
messages: Belongs to the fabD family.

29552:EXC62 RS04520
gene id: 29552:EXC62_RS04520
uniprot id: A0A449BDP4
names: Similarity
messages: Belongs to the pyruvate kinase family.

29552:EXC62 RS05530
gene id: 29552:EXC62_RS05530
uniprot id: A0A449BE85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS04300
gene id: 29552:EXC62_RS04300
uniprot id: A0A449BDI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

29552:EXC62 RS03430
gene id: 29552:EXC62_RS03430
uniprot id: A0A449BD29
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

29552:EXC62 RS05855
gene id: 29552:EXC62_RS05855
uniprot id: A0A449BES7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

29552:EXC62 RS01615
gene id: 29552:EXC62_RS01615
uniprot id: A0A449BC13
names: Similarity
messages: Belongs to the polysaccharide synthase family.

29552:EXC62 RS02675
gene id: 29552:EXC62_RS02675
uniprot id: A0A449BCM6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

29552:EXC62 RS02175
gene id: 29552:EXC62_RS02175
uniprot id: A0A449BCC0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

29552:EXC62 RS04675
gene id: 29552:EXC62_RS04675
uniprot id: A0A449BDQ5
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

29552:EXC62 RS06875
gene id: 29552:EXC62_RS06875
uniprot id: A0A449BEY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

29552:EXC62 RS05770
gene id: 29552:EXC62_RS05770
uniprot id: A0A449BEB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

29552:EXC62 RS05730
gene id: 29552:EXC62_RS05730
uniprot id: A0A449BEC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

29552:EXC62 RS00720
gene id: 29552:EXC62_RS00720
uniprot id: A0A449BBH5
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS08450
gene id: 29552:EXC62_RS08450
uniprot id: A0A449BFV8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

29552:EXC62 RS05385
gene id: 29552:EXC62_RS05385
uniprot id: A0A449BE64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS02935
gene id: 29552:EXC62_RS02935
uniprot id: A0A449BCU2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

29552:EXC62 RS07720
gene id: 29552:EXC62_RS07720
uniprot id: A0A449BFE9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

29552:EXC62 RS06125
gene id: 29552:EXC62_RS06125
uniprot id: A0A449BEI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

29552:EXC62 RS01755
gene id: 29552:EXC62_RS01755
uniprot id: A0A449BC33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

29552:EXC62 RS03990
gene id: 29552:EXC62_RS03990
uniprot id: A0A449BDC6
names: Similarity
messages: Belongs to the DEAD box helicase family.

29552:EXC62 RS03595
gene id: 29552:EXC62_RS03595
uniprot id: A0A449BD60
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

29552:EXC62 RS06615
gene id: 29552:EXC62_RS06615
uniprot id: A0A449BEV0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

29552:EXC62 RS00185
gene id: 29552:EXC62_RS00185
uniprot id: A0A449BB64
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

29552:EXC62 RS06990
gene id: 29552:EXC62_RS06990
uniprot id: A0A449BF28
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

29552:EXC62 RS04595
gene id: 29552:EXC62_RS04595
uniprot id: A0A449BDM8
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

29552:EXC62 RS04295
gene id: 29552:EXC62_RS04295
uniprot id: A0A449BDJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

29552:EXC62 RS01210
gene id: 29552:EXC62_RS01210
uniprot id: A0A449BBT1
names: Function
names: Similarity
messages: A P subtype restriction enzyme that recognizes the double-stranded unmethylated sequence 5'-GATC-3'.
messages: Belongs to the DpnII type II restriction endonuclease family.

29552:EXC62 RS02275
gene id: 29552:EXC62_RS02275
uniprot id: A0A449BCE0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

29552:EXC62 RS00665
gene id: 29552:EXC62_RS00665
uniprot id: A0A449BBE8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

29552:EXC62 RS07820
gene id: 29552:EXC62_RS07820
uniprot id: A0A449BFK1
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

29552:EXC62 RS08300
gene id: 29552:EXC62_RS08300
uniprot id: A0A449BFS3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

29552:EXC62 RS02480
gene id: 29552:EXC62_RS02480
uniprot id: A0A449BCJ4
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS01685
gene id: 29552:EXC62_RS01685
uniprot id: A0A449BC27
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

29552:EXC62 RS05000
gene id: 29552:EXC62_RS05000
uniprot id: A0A449BDW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

29552:EXC62 RS01430
gene id: 29552:EXC62_RS01430
uniprot id: A0A449BBY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Cell membrane
messages: Membrane

29552:EXC62 RS00880
gene id: 29552:EXC62_RS00880
uniprot id: A0A449BBK6
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS02420
gene id: 29552:EXC62_RS02420
uniprot id: A0A449BCI5
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

29552:EXC62 RS02620
gene id: 29552:EXC62_RS02620
uniprot id: A0A449BCL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

29552:EXC62 RS01565
gene id: 29552:EXC62_RS01565
uniprot id: A0A449BC18
names: Similarity
messages: Belongs to the ABC transporter superfamily.

29552:EXC62 RS03375
gene id: 29552:EXC62_RS03375
uniprot id: A0A449BD20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

29552:EXC62 RS04215
gene id: 29552:EXC62_RS04215
uniprot id: A0A449BDV6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

29552:EXC62 RS00525
gene id: 29552:EXC62_RS00525
uniprot id: A0A449BBD5
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

29552:EXC62 RS06140
gene id: 29552:EXC62_RS06140
uniprot id: A0A449BEK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

29552:EXC62 RS05400
gene id: 29552:EXC62_RS05400
uniprot id: A0A449BE43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS03300
gene id: 29552:EXC62_RS03300
uniprot id: A0A449BDC8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

29552:EXC62 RS02750
gene id: 29552:EXC62_RS02750
uniprot id: A0A449BCQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

29552:EXC62 RS02280
gene id: 29552:EXC62_RS02280
uniprot id: A0A449BCF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

29552:EXC62 RS01805
gene id: 29552:EXC62_RS01805
uniprot id: A0A449BC43
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

29552:EXC62 RS03625
gene id: 29552:EXC62_RS03625
uniprot id: A0A449BD41
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

29552:EXC62 RS00435
gene id: 29552:EXC62_RS00435
uniprot id: A0A449BBC1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

29552:EXC62 RS02725
gene id: 29552:EXC62_RS02725
uniprot id: A0A449BCN3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29552:EXC62 RS05520
gene id: 29552:EXC62_RS05520
uniprot id: A0A449BE59
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

29552:EXC62 RS07110
gene id: 29552:EXC62_RS07110
uniprot id: A0A449BF44
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS02255
gene id: 29552:EXC62_RS02255
uniprot id: A0A449BCP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

29552:EXC62 RS05485
gene id: 29552:EXC62_RS05485
uniprot id: A0A449BE81
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

29552:EXC62 RS02685
gene id: 29552:EXC62_RS02685
uniprot id: A0A449BCN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

29552:EXC62 RS03580
gene id: 29552:EXC62_RS03580
uniprot id: A0A449BD58
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29552:EXC62 RS05455
gene id: 29552:EXC62_RS05455
uniprot id: A0A449BE51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

29552:EXC62 RS04460
gene id: 29552:EXC62_RS04460
uniprot id: A0A449BDL3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

29552:EXC62 RS06980
gene id: 29552:EXC62_RS06980
uniprot id: A0A449BFE2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

29552:EXC62 RS06480
gene id: 29552:EXC62_RS06480
uniprot id: A0A449BET4
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS02665
gene id: 29552:EXC62_RS02665
uniprot id: A0A449BCN2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

29552:EXC62 RS01705
gene id: 29552:EXC62_RS01705
uniprot id: A0A449BC23
names: Similarity
messages: Belongs to the polysaccharide synthase family.

29552:EXC62 RS03765
gene id: 29552:EXC62_RS03765
uniprot id: A0A449BDA1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

29552:EXC62 RS00915
gene id: 29552:EXC62_RS00915
uniprot id: A0A449BBK1
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS01060
gene id: 29552:EXC62_RS01060
uniprot id: A0A449BBP9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

29552:EXC62 RS07620
gene id: 29552:EXC62_RS07620
uniprot id: A0A449BFD0
names: Similarity
messages: Belongs to the aldose epimerase family.

29552:EXC62 RS04850
gene id: 29552:EXC62_RS04850
uniprot id: A0A449BDT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

29552:EXC62 RS00890
gene id: 29552:EXC62_RS00890
uniprot id: A0A449BBL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS02295
gene id: 29552:EXC62_RS02295
uniprot id: A0A449BCF9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

29552:EXC62 RS05895
gene id: 29552:EXC62_RS05895
uniprot id: A0A449BEG4
names: Similarity
messages: Belongs to the LOG family.

29552:EXC62 RS02245
gene id: 29552:EXC62_RS02245
uniprot id: A0A449BCE7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

29552:EXC62 RS07840
gene id: 29552:EXC62_RS07840
uniprot id: A0A449BFJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

29552:EXC62 RS07565
gene id: 29552:EXC62_RS07565
uniprot id: A0A449BFD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

29552:EXC62 RS06750
gene id: 29552:EXC62_RS06750
uniprot id: A0A449BEY1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

29552:EXC62 RS00490
gene id: 29552:EXC62_RS00490
uniprot id: A0A449BBD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

29552:EXC62 RS07150
gene id: 29552:EXC62_RS07150
uniprot id: A0A449BF31
names: Similarity
messages: Belongs to the AlaDH/PNT family.

29552:EXC62 RS04340
gene id: 29552:EXC62_RS04340
uniprot id: A0A449BDI5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

29552:EXC62 RS08360
gene id: 29552:EXC62_RS08360
uniprot id: A0A449BFX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

29552:EXC62 RS01665
gene id: 29552:EXC62_RS01665
uniprot id: A0A449BC24
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

29552:EXC62 RS05775
gene id: 29552:EXC62_RS05775
uniprot id: A0A449BEB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

29552:EXC62 RS03265
gene id: 29552:EXC62_RS03265
uniprot id: A0A449BCX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

29552:EXC62 RS03140
gene id: 29552:EXC62_RS03140
uniprot id: A0A449BCX9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

29552:EXC62 RS06270
gene id: 29552:EXC62_RS06270
uniprot id: A0A449BEK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

29552:EXC62 RS04510
gene id: 29552:EXC62_RS04510
uniprot id: A0A449BDM3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

29552:EXC62 RS05830
gene id: 29552:EXC62_RS05830
uniprot id: A0A449BEE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

29552:EXC62 RS06185
gene id: 29552:EXC62_RS06185
uniprot id: A0A449BEL5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

29552:EXC62 RS03935
gene id: 29552:EXC62_RS03935
uniprot id: A0A449BDE1
names: Subcellular Location Annotation
messages: Membrane

29552:EXC62 RS06825
gene id: 29552:EXC62_RS06825
uniprot id: A0A449BEX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

29552:EXC62 RS02110
gene id: 29552:EXC62_RS02110
uniprot id: A0A449BCA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

29552:EXC62 RS05275
gene id: 29552:EXC62_RS05275
uniprot id: A0A449BE32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

29552:EXC62 RS01695
gene id: 29552:EXC62_RS01695
uniprot id: A0A449BC29
names: Similarity
messages: Belongs to the glutamine synthetase family.

29552:EXC62 RS06960
gene id: 29552:EXC62_RS06960
uniprot id: A0A449BF14
names: Similarity
messages: Belongs to the peptidase U62 family.

29552:EXC62 RS02270
gene id: 29552:EXC62_RS02270
uniprot id: A0A449BCE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

29552:EXC62 RS02820
gene id: 29552:EXC62_RS02820
uniprot id: A0A449BCR7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

29552:EXC62 RS04305
gene id: 29552:EXC62_RS04305
uniprot id: A0A449BDK9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

29552:EXC62 RS04335
gene id: 29552:EXC62_RS04335
uniprot id: A0A449BDH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

29552:EXC62 RS03495
gene id: 29552:EXC62_RS03495
uniprot id: A0A449BD42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

29552:EXC62 RS02370
gene id: 29552:EXC62_RS02370
uniprot id: A0A449BCH5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

29552:EXC62 RS06945
gene id: 29552:EXC62_RS06945
uniprot id: A0A449BEY7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

29552:EXC62 RS07825
gene id: 29552:EXC62_RS07825
uniprot id: A0A449BFI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

29552:EXC62 RS07390
gene id: 29552:EXC62_RS07390
uniprot id: A0A449BF97
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

29552:EXC62 RS04060
gene id: 29552:EXC62_RS04060
uniprot id: A0A449BDC2
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.