29379:I6G39 RS07365
gene id: 29379:I6G39_RS07365
uniprot id: A0A2K4C4H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

29379:I6G39 RS01530
gene id: 29379:I6G39_RS01530
uniprot id: A0A2K4BYU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

29379:I6G39 RS02505
gene id: 29379:I6G39_RS02505
uniprot id: A0A2K4C0E4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

29379:I6G39 RS02665
gene id: 29379:I6G39_RS02665
uniprot id: A0A2K4C0A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS00840
gene id: 29379:I6G39_RS00840
uniprot id: A0A2K4BZ35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

29379:I6G39 RS04725
gene id: 29379:I6G39_RS04725
uniprot id: A0A2K4C3Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

29379:I6G39 RS01565
gene id: 29379:I6G39_RS01565
uniprot id: A0A2K4BYX0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

29379:I6G39 RS06580
gene id: 29379:I6G39_RS06580
uniprot id: A0A2K4C1P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS09990
gene id: 29379:I6G39_RS09990
uniprot id: A0A2K4BZ68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

29379:I6G39 RS06575
gene id: 29379:I6G39_RS06575
uniprot id: A0A2K4C1P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

29379:I6G39 RS05385
gene id: 29379:I6G39_RS05385
uniprot id: A0A2K4BX17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

29379:I6G39 RS04065
gene id: 29379:I6G39_RS04065
uniprot id: A0A2K4BZR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

29379:I6G39 RS05945
gene id: 29379:I6G39_RS05945
uniprot id: A0A2K4BV26
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

29379:I6G39 RS02720
gene id: 29379:I6G39_RS02720
uniprot id: A0A2K4C0C9
names: Subcellular Location Annotation
messages: Cell membrane

29379:I6G39 RS06680
gene id: 29379:I6G39_RS06680
uniprot id: A0A2K4C1L4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

29379:I6G39 RS05280
gene id: 29379:I6G39_RS05280
uniprot id: A0A2K4C0V0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

29379:I6G39 RS08695
gene id: 29379:I6G39_RS08695
uniprot id: A0A2K4BZG6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

29379:I6G39 RS02860
gene id: 29379:I6G39_RS02860
uniprot id: A0A2K4C087
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS05620
gene id: 29379:I6G39_RS05620
uniprot id: A0A2K4BUV5
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

29379:I6G39 RS09060
gene id: 29379:I6G39_RS09060
uniprot id: A0A2K4C4I8
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

29379:I6G39 RS10025
gene id: 29379:I6G39_RS10025
uniprot id: A0A2K4C0M1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

29379:I6G39 RS06255
gene id: 29379:I6G39_RS06255
uniprot id: A0A2K4C486
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS08955
gene id: 29379:I6G39_RS08955
uniprot id: A0A2K4C4F1
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

29379:I6G39 RS02870
gene id: 29379:I6G39_RS02870
uniprot id: A0A2K4C095
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

29379:I6G39 RS00620
gene id: 29379:I6G39_RS00620
uniprot id: A0A2K4C1Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA which binds and tethers DNA polymerases and other proteins to the DNA. The DNA replisome complex has a single clamp-loading complex (3 tau and 1 each of delta, delta', psi and chi subunits) which binds 3 Pol III cores (1 core on the leading strand and 2 on the lagging strand) each with a beta sliding clamp dimer. Additional proteins in the replisome are other copies of gamma, psi and chi, Ssb, DNA helicase and RNA primase.

29379:I6G39 RS00775
gene id: 29379:I6G39_RS00775
uniprot id: A0A2K4BWX1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

29379:I6G39 RS04815
gene id: 29379:I6G39_RS04815
uniprot id: A0A2K4C417
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

29379:I6G39 RS04990
gene id: 29379:I6G39_RS04990
uniprot id: A0A2K4BUK3
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

29379:I6G39 RS02945
gene id: 29379:I6G39_RS02945
uniprot id: A0A2K4C1K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

29379:I6G39 RS04145
gene id: 29379:I6G39_RS04145
uniprot id: A0A2K4BZR9
names: Similarity
messages: Belongs to the peptidase C56 family.

29379:I6G39 RS05685
gene id: 29379:I6G39_RS05685
uniprot id: A0A2K4BW42
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

29379:I6G39 RS01975
gene id: 29379:I6G39_RS01975
uniprot id: A0A2K4C2L5
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS00235
gene id: 29379:I6G39_RS00235
uniprot id: A0A2K4BWA9
names: Subcellular Location Annotation
messages: Cytoplasm

29379:I6G39 RS08595
gene id: 29379:I6G39_RS08595
uniprot id: A0A2K4BVM1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

29379:I6G39 RS08160
gene id: 29379:I6G39_RS08160
uniprot id: A0A2K4C246
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS02140
gene id: 29379:I6G39_RS02140
uniprot id: A0A2K4C2I9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

29379:I6G39 RS06755
gene id: 29379:I6G39_RS06755
uniprot id: A0A2K4C4U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS01355
gene id: 29379:I6G39_RS01355
uniprot id: A0A2K4BW43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

29379:I6G39 RS07175
gene id: 29379:I6G39_RS07175
uniprot id: A0A2K4BZ48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

29379:I6G39 RS08765
gene id: 29379:I6G39_RS08765
uniprot id: A0A2K4BZG4
names: Similarity
messages: Belongs to the ArsC family.

29379:I6G39 RS04950
gene id: 29379:I6G39_RS04950
uniprot id: A0A2K4C461
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

29379:I6G39 RS06115
gene id: 29379:I6G39_RS06115
uniprot id: A0A2K4BWD7
names: Similarity
messages: Belongs to the asparaginase 1 family.

29379:I6G39 RS05205
gene id: 29379:I6G39_RS05205
uniprot id: A0A2K4C109
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

29379:I6G39 RS05725
gene id: 29379:I6G39_RS05725
uniprot id: A0A2K4BUW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

29379:I6G39 RS05795
gene id: 29379:I6G39_RS05795
uniprot id: A0A2K4BW66
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

29379:I6G39 RS10310
gene id: 29379:I6G39_RS10310
uniprot id: A0A2K4C212
names: Similarity
messages: In the N-terminal section; belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

29379:I6G39 RS01990
gene id: 29379:I6G39_RS01990
uniprot id: A0A2K4C2T0
names: Similarity
messages: Belongs to the ChdC family. Type 1 subfamily.

29379:I6G39 RS10600
gene id: 29379:I6G39_RS10600
uniprot id: A0A2K4BXK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

29379:I6G39 RS07895
gene id: 29379:I6G39_RS07895
uniprot id: A0A2K4BU12
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

29379:I6G39 RS08730
gene id: 29379:I6G39_RS08730
uniprot id: A0A7T3A737
names: Similarity
messages: Belongs to the PemK/MazF family.

29379:I6G39 RS06900
gene id: 29379:I6G39_RS06900
uniprot id: A0A2K4C617
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

29379:I6G39 RS05095
gene id: 29379:I6G39_RS05095
uniprot id: A0A2K4BYA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

29379:I6G39 RS05745
gene id: 29379:I6G39_RS05745
uniprot id: A0A2K4BW56
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

29379:I6G39 RS06925
gene id: 29379:I6G39_RS06925
uniprot id: A0A2K4C4P9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

29379:I6G39 RS10070
gene id: 29379:I6G39_RS10070
uniprot id: A0A2K4BUP0
names: Similarity
messages: Belongs to the fructosamine kinase family.

29379:I6G39 RS05870
gene id: 29379:I6G39_RS05870
uniprot id: A0A2K4BUZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

29379:I6G39 RS03525
gene id: 29379:I6G39_RS03525
uniprot id: A0A2K4C3L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

29379:I6G39 RS03615
gene id: 29379:I6G39_RS03615
uniprot id: A0A2K4C3L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

29379:I6G39 RS05415
gene id: 29379:I6G39_RS05415
uniprot id: A0A2K4BX09
names: Similarity
messages: Belongs to the RecJ family.

29379:I6G39 RS09430
gene id: 29379:I6G39_RS09430
uniprot id: A0A2K4C189
names: Similarity
messages: Belongs to the UPF0111 family.

29379:I6G39 RS07215
gene id: 29379:I6G39_RS07215
uniprot id: A0A2K4BZ69
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

29379:I6G39 RS02625
gene id: 29379:I6G39_RS02625
uniprot id: A0A7T3E346
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

29379:I6G39 RS03365
gene id: 29379:I6G39_RS03365
uniprot id: A0A2K4C3N7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

29379:I6G39 RS03530
gene id: 29379:I6G39_RS03530
uniprot id: A0A2K4C3M2
names: Similarity
messages: Belongs to the ThiD family.

29379:I6G39 RS00215
gene id: 29379:I6G39_RS00215
uniprot id: A0A2K4BWA1
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

29379:I6G39 RS07800
gene id: 29379:I6G39_RS07800
uniprot id: A0A2K4BU24
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

29379:I6G39 RS04570
gene id: 29379:I6G39_RS04570
uniprot id: A0A2K4BWR5
names: Similarity
messages: Belongs to the UPF0342 family.

29379:I6G39 RS02745
gene id: 29379:I6G39_RS02745
uniprot id: A0A2K4C0B0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

29379:I6G39 RS05500
gene id: 29379:I6G39_RS05500
uniprot id: A0A2K4BUR9
names: Similarity
messages: Belongs to the UPF0297 family.

29379:I6G39 RS10370
gene id: 29379:I6G39_RS10370
uniprot id: A0A2K4C1V8
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS05905
gene id: 29379:I6G39_RS05905
uniprot id: A0A2K4BUZ5
names: Similarity
messages: Belongs to the peptidase M24B family.

29379:I6G39 RS03805
gene id: 29379:I6G39_RS03805
uniprot id: A0A2K4C2C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AgrB family.
messages: Cell membrane
messages: Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of AgrD, the precursor of AIP.

29379:I6G39 RS02750
gene id: 29379:I6G39_RS02750
uniprot id: A0A2K4C0A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

29379:I6G39 RS06550
gene id: 29379:I6G39_RS06550
uniprot id: A0A2K4BWW1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS06155
gene id: 29379:I6G39_RS06155
uniprot id: A0A2K4BWX9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

29379:I6G39 RS06590
gene id: 29379:I6G39_RS06590
uniprot id: A0A2K4C1U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

29379:I6G39 RS07250
gene id: 29379:I6G39_RS07250
uniprot id: A0A2K4C398
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

29379:I6G39 RS09630
gene id: 29379:I6G39_RS09630
uniprot id: A0A2K4C1K8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS08870
gene id: 29379:I6G39_RS08870
uniprot id: A0A2K4BYY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

29379:I6G39 RS08310
gene id: 29379:I6G39_RS08310
uniprot id: A0A2K4BXW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS03160
gene id: 29379:I6G39_RS03160
uniprot id: A0A2K4BY39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multidrug resistance efflux pump SepA family.
messages: Cell membrane
messages: Involved in multidrug efflux.

29379:I6G39 RS07040
gene id: 29379:I6G39_RS07040
uniprot id: A0A2K4C4V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

29379:I6G39 RS01360
gene id: 29379:I6G39_RS01360
uniprot id: A0A2K4BW20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

29379:I6G39 RS08435
gene id: 29379:I6G39_RS08435
uniprot id: A0A2X5CY25
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

29379:I6G39 RS03240
gene id: 29379:I6G39_RS03240
uniprot id: A0A2K4C3Q0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

29379:I6G39 RS08335
gene id: 29379:I6G39_RS08335
uniprot id: A0A2K4BXW5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

29379:I6G39 RS06180
gene id: 29379:I6G39_RS06180
uniprot id: A0A2K4BWX4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

29379:I6G39 RS04000
gene id: 29379:I6G39_RS04000
uniprot id: A0A2K4BZN8
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

29379:I6G39 RS06645
gene id: 29379:I6G39_RS06645
uniprot id: A0A2K4C1N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

29379:I6G39 RS09350
gene id: 29379:I6G39_RS09350
uniprot id: A0A2K4C1A0
names: Similarity
messages: Belongs to the LOG family.

29379:I6G39 RS06730
gene id: 29379:I6G39_RS06730
uniprot id: A0A2K4C4V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

29379:I6G39 RS10530
gene id: 29379:I6G39_RS10530
uniprot id: A0A2K4BXN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS04030
gene id: 29379:I6G39_RS04030
uniprot id: A0A2K4BZR4
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

29379:I6G39 RS08200
gene id: 29379:I6G39_RS08200
uniprot id: A0A2K4C217
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. YjcG family.

29379:I6G39 RS05490
gene id: 29379:I6G39_RS05490
uniprot id: A0A2K4BUT5
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

29379:I6G39 RS01000
gene id: 29379:I6G39_RS01000
uniprot id: A0A2K4BWP0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

29379:I6G39 RS00860
gene id: 29379:I6G39_RS00860
uniprot id: A0A2K4BVI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane

29379:I6G39 RS08655
gene id: 29379:I6G39_RS08655
uniprot id: A0A2K4BWU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

29379:I6G39 RS01410
gene id: 29379:I6G39_RS01410
uniprot id: A0A2K4BYU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

29379:I6G39 RS08195
gene id: 29379:I6G39_RS08195
uniprot id: A0A2X5A6X0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS08240
gene id: 29379:I6G39_RS08240
uniprot id: A0A2K4BWH4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

29379:I6G39 RS03380
gene id: 29379:I6G39_RS03380
uniprot id: A0A2K4C3V6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS10115
gene id: 29379:I6G39_RS10115
uniprot id: A0A2K4BYT0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

29379:I6G39 RS10345
gene id: 29379:I6G39_RS10345
uniprot id: A0A2K4C231
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

29379:I6G39 RS05380
gene id: 29379:I6G39_RS05380
uniprot id: A0A2K4BWZ9
names: Similarity
messages: Belongs to the UPF0735 family.

29379:I6G39 RS01210
gene id: 29379:I6G39_RS01210
uniprot id: A0A2K4BUC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS01140
gene id: 29379:I6G39_RS01140
uniprot id: A0A2K4BVC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

29379:I6G39 RS00095
gene id: 29379:I6G39_RS00095
uniprot id: A0A2K4C0R9
names: Function
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.

29379:I6G39 RS07135
gene id: 29379:I6G39_RS07135
uniprot id: A0A2K4C4K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

29379:I6G39 RS08015
gene id: 29379:I6G39_RS08015
uniprot id: A0A2K4C188
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS08910
gene id: 29379:I6G39_RS08910
uniprot id: A0A2K4BZ17
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

29379:I6G39 RS07490
gene id: 29379:I6G39_RS07490
uniprot id: A0A2K4C332
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

29379:I6G39 RS05185
gene id: 29379:I6G39_RS05185
uniprot id: A0A2K4C0W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

29379:I6G39 RS06205
gene id: 29379:I6G39_RS06205
uniprot id: A0A2K4C476
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

29379:I6G39 RS03735
gene id: 29379:I6G39_RS03735
uniprot id: A0A2K4C2I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

29379:I6G39 RS08620
gene id: 29379:I6G39_RS08620
uniprot id: A0A2K4BUC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

29379:I6G39 RS06495
gene id: 29379:I6G39_RS06495
uniprot id: A0A2K4BWW9
names: Similarity
messages: Belongs to the TelA family.

29379:I6G39 RS02215
gene id: 29379:I6G39_RS02215
uniprot id: A0A2K4C3U4
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS08710
gene id: 29379:I6G39_RS08710
uniprot id: A0A2K4BZI5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

29379:I6G39 RS05110
gene id: 29379:I6G39_RS05110
uniprot id: A0A2K4BVS6
names: Similarity
messages: Belongs to the peptidase M24B family.

29379:I6G39 RS09410
gene id: 29379:I6G39_RS09410
uniprot id: A0A2K4C145
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

29379:I6G39 RS06360
gene id: 29379:I6G39_RS06360
uniprot id: A0A2K4C4A6
names: Similarity
messages: Belongs to the CvfC family.

29379:I6G39 RS03355
gene id: 29379:I6G39_RS03355
uniprot id: A0A2K4C3N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

29379:I6G39 RS10280
gene id: 29379:I6G39_RS10280
uniprot id: A0A2K4C1X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS07130
gene id: 29379:I6G39_RS07130
uniprot id: A0A2K4C4M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

29379:I6G39 RS04910
gene id: 29379:I6G39_RS04910
uniprot id: A0A2K4C5E8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS09220
gene id: 29379:I6G39_RS09220
uniprot id: A0A2K4C4B4
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

29379:I6G39 RS05255
gene id: 29379:I6G39_RS05255
uniprot id: A0A2K4C0W4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

29379:I6G39 RS05150
gene id: 29379:I6G39_RS05150
uniprot id: A0A2K4C0Y8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS08465
gene id: 29379:I6G39_RS08465
uniprot id: A0A2K4C2R1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

29379:I6G39 RS01995
gene id: 29379:I6G39_RS01995
uniprot id: A0A2K4C2M3
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

29379:I6G39 RS02465
gene id: 29379:I6G39_RS02465
uniprot id: A0A2K4C1S9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS09325
gene id: 29379:I6G39_RS09325
uniprot id: A0A2K4C164
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

29379:I6G39 RS06005
gene id: 29379:I6G39_RS06005
uniprot id: A0A2K4BV14
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

29379:I6G39 RS07240
gene id: 29379:I6G39_RS07240
uniprot id: A0A2K4C383
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

29379:I6G39 RS08330
gene id: 29379:I6G39_RS08330
uniprot id: A0A2K4BXV1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

29379:I6G39 RS02405
gene id: 29379:I6G39_RS02405
uniprot id: A0A2K4C0J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

29379:I6G39 RS09590
gene id: 29379:I6G39_RS09590
uniprot id: A0A2K4C1G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS09855
gene id: 29379:I6G39_RS09855
uniprot id: A0A2K4BYL2
names: Similarity
messages: Belongs to the CapA family.

29379:I6G39 RS05710
gene id: 29379:I6G39_RS05710
uniprot id: A0A2K4BUW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

29379:I6G39 RS02275
gene id: 29379:I6G39_RS02275
uniprot id: A0A2K4C0K9
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

29379:I6G39 RS02420
gene id: 29379:I6G39_RS02420
uniprot id: A0A2K4C0K1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS04025
gene id: 29379:I6G39_RS04025
uniprot id: A0A2K4C132
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

29379:I6G39 RS09725
gene id: 29379:I6G39_RS09725
uniprot id: A0A2K4BXQ4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

29379:I6G39 RS04925
gene id: 29379:I6G39_RS04925
uniprot id: A0A2K4C438
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

29379:I6G39 RS08415
gene id: 29379:I6G39_RS08415
uniprot id: A0A2K4C447
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS01190
gene id: 29379:I6G39_RS01190
uniprot id: A0A2K4BXZ8
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

29379:I6G39 RS02935
gene id: 29379:I6G39_RS02935
uniprot id: A0A2K4C057
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

29379:I6G39 RS02055
gene id: 29379:I6G39_RS02055
uniprot id: A0A2K4C2Q5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

29379:I6G39 RS03030
gene id: 29379:I6G39_RS03030
uniprot id: A0A2K4C069
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS00790
gene id: 29379:I6G39_RS00790
uniprot id: A0A2K4BVP7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

29379:I6G39 RS03010
gene id: 29379:I6G39_RS03010
uniprot id: A0A2K4C060
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

29379:I6G39 RS01540
gene id: 29379:I6G39_RS01540
uniprot id: A0A2K4BYY7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

29379:I6G39 RS00895
gene id: 29379:I6G39_RS00895
uniprot id: A0A2K4BVG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

29379:I6G39 RS02165
gene id: 29379:I6G39_RS02165
uniprot id: A0A2K4C2M6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS02950
gene id: 29379:I6G39_RS02950
uniprot id: A0A2K4C066
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

29379:I6G39 RS06830
gene id: 29379:I6G39_RS06830
uniprot id: A0A2K4C4Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.
messages: Cytoplasm

29379:I6G39 RS09775
gene id: 29379:I6G39_RS09775
uniprot id: A0A2K4BYI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS00035
gene id: 29379:I6G39_RS00035
uniprot id: A0A2K4C0P7
names: Similarity
messages: Belongs to the UPF0355 family.

29379:I6G39 RS04715
gene id: 29379:I6G39_RS04715
uniprot id: A0A2K4C3Z5
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

29379:I6G39 RS07890
gene id: 29379:I6G39_RS07890
uniprot id: A0A2K4BU18
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

29379:I6G39 RS03050
gene id: 29379:I6G39_RS03050
uniprot id: A0A2K4C044
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

29379:I6G39 RS02520
gene id: 29379:I6G39_RS02520
uniprot id: A0A2K4C0E5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

29379:I6G39 RS04070
gene id: 29379:I6G39_RS04070
uniprot id: A0A2K4BZP6
names: Similarity
messages: Belongs to the UPF0421 family.

29379:I6G39 RS02925
gene id: 29379:I6G39_RS02925
uniprot id: A0A2K4C085
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

29379:I6G39 RS06300
gene id: 29379:I6G39_RS06300
uniprot id: A0A2K4C2X4
names: Similarity
messages: Belongs to the UPF0398 family.

29379:I6G39 RS01550
gene id: 29379:I6G39_RS01550
uniprot id: A0A2K4BYY3
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

29379:I6G39 RS03105
gene id: 29379:I6G39_RS03105
uniprot id: A0A2K4BY48
names: Similarity
messages: Belongs to the IucA/IucC family.

29379:I6G39 RS06090
gene id: 29379:I6G39_RS06090
uniprot id: A0A2K4BV27
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

29379:I6G39 RS07640
gene id: 29379:I6G39_RS07640
uniprot id: A0A2K4BU52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS10595
gene id: 29379:I6G39_RS10595
uniprot id: A0A2K4BXI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Forms a heterotetramer with 2 subunits each of GtfA and GtfB. Part of the accessory SecA2/SecY2 protein translocation apparatus.
messages: Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. Catalyzes the first step in glycosylation by transferring N-acetylglucosamine from UDP-GlcNAc to serine residues in the substrate protein. Part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon.

29379:I6G39 RS07935
gene id: 29379:I6G39_RS07935
uniprot id: A0A2K4BTZ6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

29379:I6G39 RS05470
gene id: 29379:I6G39_RS05470
uniprot id: A0A2K4BUR2
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

29379:I6G39 RS05145
gene id: 29379:I6G39_RS05145
uniprot id: A0A2K4C106
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

29379:I6G39 RS09530
gene id: 29379:I6G39_RS09530
uniprot id: A0A2K4BXB0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

29379:I6G39 RS09760
gene id: 29379:I6G39_RS09760
uniprot id: A0A2K4BXR6
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS07575
gene id: 29379:I6G39_RS07575
uniprot id: A0A2K4BU80
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

29379:I6G39 RS01750
gene id: 29379:I6G39_RS01750
uniprot id: A0A2K4BYB5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

29379:I6G39 RS05715
gene id: 29379:I6G39_RS05715
uniprot id: A0A2K4BUV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

29379:I6G39 RS05190
gene id: 29379:I6G39_RS05190
uniprot id: A0A2K4C118
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

29379:I6G39 RS08110
gene id: 29379:I6G39_RS08110
uniprot id: A0A2K4C3I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacteriophage holin family. Cp-1 holin subfamily.
messages: Membrane

29379:I6G39 RS09945
gene id: 29379:I6G39_RS09945
uniprot id: A0A2K4BYH0
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

29379:I6G39 RS00675
gene id: 29379:I6G39_RS00675
uniprot id: A0A2K4BVM4
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS09395
gene id: 29379:I6G39_RS09395
uniprot id: A0A2K4C131
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

29379:I6G39 RS03375
gene id: 29379:I6G39_RS03375
uniprot id: A0A2K4C3P9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

29379:I6G39 RS05410
gene id: 29379:I6G39_RS05410
uniprot id: A0A2K4BX03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

29379:I6G39 RS01260
gene id: 29379:I6G39_RS01260
uniprot id: A0A2K4BW09
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

29379:I6G39 RS05030
gene id: 29379:I6G39_RS05030
uniprot id: A0A2K4BYA6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

29379:I6G39 RS07235
gene id: 29379:I6G39_RS07235
uniprot id: A0A2K4C384
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

29379:I6G39 RS09830
gene id: 29379:I6G39_RS09830
uniprot id: A0A2K4BYK1
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS02975
gene id: 29379:I6G39_RS02975
uniprot id: A0A2K4C075
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

29379:I6G39 RS07620
gene id: 29379:I6G39_RS07620
uniprot id: A0A2K4BU63
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

29379:I6G39 RS07700
gene id: 29379:I6G39_RS07700
uniprot id: A0A2K4BU64
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

29379:I6G39 RS08290
gene id: 29379:I6G39_RS08290
uniprot id: A0A2K4BWI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

29379:I6G39 RS02965
gene id: 29379:I6G39_RS02965
uniprot id: A0A2K4C071
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

29379:I6G39 RS06430
gene id: 29379:I6G39_RS06430
uniprot id: A0A2K4C362
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS05075
gene id: 29379:I6G39_RS05075
uniprot id: A0A2K4BY75
names: Similarity
messages: Belongs to the peptidase S49 family.

29379:I6G39 RS05950
gene id: 29379:I6G39_RS05950
uniprot id: A0A2K4BV05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

29379:I6G39 RS07220
gene id: 29379:I6G39_RS07220
uniprot id: A0A2K4C0J5
names: Similarity
messages: Belongs to the peptidase C69 family.

29379:I6G39 RS08210
gene id: 29379:I6G39_RS08210
uniprot id: A0A2K4C240
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS06620
gene id: 29379:I6G39_RS06620
uniprot id: A0A2K4C1T3
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

29379:I6G39 RS08545
gene id: 29379:I6G39_RS08545
uniprot id: A0A2K4C515
names: Similarity
messages: Belongs to the UPF0349 family.

29379:I6G39 RS02885
gene id: 29379:I6G39_RS02885
uniprot id: A0A2K4C067
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

29379:I6G39 RS04755
gene id: 29379:I6G39_RS04755
uniprot id: A0A2K4C446
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

29379:I6G39 RS07340
gene id: 29379:I6G39_RS07340
uniprot id: A0A2K4C356
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

29379:I6G39 RS00645
gene id: 29379:I6G39_RS00645
uniprot id: A0A2K4C1U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

29379:I6G39 RS02900
gene id: 29379:I6G39_RS02900
uniprot id: A0A2K4C074
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

29379:I6G39 RS04150
gene id: 29379:I6G39_RS04150
uniprot id: A0A2K4BZS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation using lipid-linked disaccharide-pentapeptide as the substrate.

29379:I6G39 RS01985
gene id: 29379:I6G39_RS01985
uniprot id: A0A2K4C2K8
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

29379:I6G39 RS07420
gene id: 29379:I6G39_RS07420
uniprot id: A0A2K4C4G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

29379:I6G39 RS03395
gene id: 29379:I6G39_RS03395
uniprot id: A0A2K4C3U7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS08425
gene id: 29379:I6G39_RS08425
uniprot id: A0A2K4C2R3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS06670
gene id: 29379:I6G39_RS06670
uniprot id: A0A2K4C1R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

29379:I6G39 RS03000
gene id: 29379:I6G39_RS03000
uniprot id: A0A2K4C054
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

29379:I6G39 RS01660
gene id: 29379:I6G39_RS01660
uniprot id: A0A2K4BZR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

29379:I6G39 RS08295
gene id: 29379:I6G39_RS08295
uniprot id: A0A2K4BXX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

29379:I6G39 RS06740
gene id: 29379:I6G39_RS06740
uniprot id: A0A2K4C651
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

29379:I6G39 RS01135
gene id: 29379:I6G39_RS01135
uniprot id: A0A2K4BVC4
names: Similarity
messages: Belongs to the UPF0355 family.

29379:I6G39 RS07335
gene id: 29379:I6G39_RS07335
uniprot id: A0A2K4C366
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. Confers resistance to some classes of antibiotics.

29379:I6G39 RS10250
gene id: 29379:I6G39_RS10250
uniprot id: A0A2K4BX15
names: Similarity
messages: Belongs to the bacterial solute-binding protein 8 family.

29379:I6G39 RS05560
gene id: 29379:I6G39_RS05560
uniprot id: A0A2K4BUT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

29379:I6G39 RS07595
gene id: 29379:I6G39_RS07595
uniprot id: A0A2K4BU66
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

29379:I6G39 RS10375
gene id: 29379:I6G39_RS10375
uniprot id: A0A2K4C218
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

29379:I6G39 RS01710
gene id: 29379:I6G39_RS01710
uniprot id: A0A2K4BZQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

29379:I6G39 RS07180
gene id: 29379:I6G39_RS07180
uniprot id: A0A2K4BZ66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

29379:I6G39 RS00570
gene id: 29379:I6G39_RS00570
uniprot id: A0A2K4BTU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

29379:I6G39 RS00055
gene id: 29379:I6G39_RS00055
uniprot id: A0A2K4C0T3
names: Function
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.

29379:I6G39 RS03005
gene id: 29379:I6G39_RS03005
uniprot id: A0A2K4C073
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

29379:I6G39 RS09600
gene id: 29379:I6G39_RS09600
uniprot id: A0A2K4C1H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

29379:I6G39 RS00100
gene id: 29379:I6G39_RS00100
uniprot id: A0A2K4C0P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane
messages: Probably required for nitrate uptake under anoxic conditions. Also possibly involved in excretion of nitrite produced by the dissimilatory reduction of nitrate.

29379:I6G39 RS03325
gene id: 29379:I6G39_RS03325
uniprot id: A0A2K4C3S3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

29379:I6G39 RS02905
gene id: 29379:I6G39_RS02905
uniprot id: A0A2K4C094
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

29379:I6G39 RS08305
gene id: 29379:I6G39_RS08305
uniprot id: A0A2K4BXW6
names: Caution
names: Similarity
messages: Belongs to the ABC transporter superfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

29379:I6G39 RS02270
gene id: 29379:I6G39_RS02270
uniprot id: A0A2K4C0L5
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS03930
gene id: 29379:I6G39_RS03930
uniprot id: A0A2K4BZK9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

29379:I6G39 RS07105
gene id: 29379:I6G39_RS07105
uniprot id: A0A2K4C4S1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

29379:I6G39 RS06655
gene id: 29379:I6G39_RS06655
uniprot id: A0A2K4C1R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS03305
gene id: 29379:I6G39_RS03305
uniprot id: A0A2K4C3Q2
names: Similarity
messages: Belongs to the Dps family.

29379:I6G39 RS07900
gene id: 29379:I6G39_RS07900
uniprot id: A0A2K4BU05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

29379:I6G39 RS00110
gene id: 29379:I6G39_RS00110
uniprot id: A0A2K4C0V8
names: Cofactor
names: Function
names: PTM
names: Subcellular Location Annotation
messages: Autophosphorylated.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

29379:I6G39 RS07305
gene id: 29379:I6G39_RS07305
uniprot id: A0A2K4C382
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

29379:I6G39 RS02170
gene id: 29379:I6G39_RS02170
uniprot id: A0A2K4C2H6
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS01920
gene id: 29379:I6G39_RS01920
uniprot id: A0A2K4C2M4
names: Function
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.
messages: Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate.

29379:I6G39 RS09610
gene id: 29379:I6G39_RS09610
uniprot id: A0A2K4C1G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS03715
gene id: 29379:I6G39_RS03715
uniprot id: A0A2K4C2E9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS06060
gene id: 29379:I6G39_RS06060
uniprot id: A0A2K4BV23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

29379:I6G39 RS01885
gene id: 29379:I6G39_RS01885
uniprot id: A0A2K4C190
names: Similarity
names: Subunit
messages: Belongs to the azoreductase type 2 family.
messages: Homotetramer.

29379:I6G39 RS04090
gene id: 29379:I6G39_RS04090
uniprot id: A0A2K4BZS8
names: Subcellular Location Annotation
messages: Cell membrane

29379:I6G39 RS02265
gene id: 29379:I6G39_RS02265
uniprot id: A0A2K4C0I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

29379:I6G39 RS07440
gene id: 29379:I6G39_RS07440
uniprot id: A0A2K4C341
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

29379:I6G39 RS09250
gene id: 29379:I6G39_RS09250
uniprot id: A0A2K4C487
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

29379:I6G39 RS01535
gene id: 29379:I6G39_RS01535
uniprot id: A0A2K4C0A1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

29379:I6G39 RS05100
gene id: 29379:I6G39_RS05100
uniprot id: A0A2K4BY94
names: Similarity
messages: Belongs to the universal stress protein A family.

29379:I6G39 RS00190
gene id: 29379:I6G39_RS00190
uniprot id: A0A2K4BWB3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

29379:I6G39 RS08325
gene id: 29379:I6G39_RS08325
uniprot id: A0A2K4BXX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS06920
gene id: 29379:I6G39_RS06920
uniprot id: A0A2K4C4R8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

29379:I6G39 RS03470
gene id: 29379:I6G39_RS03470
uniprot id: A0A2K4C3M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

29379:I6G39 RS02980
gene id: 29379:I6G39_RS02980
uniprot id: A0A2K4C077
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

29379:I6G39 RS00560
gene id: 29379:I6G39_RS00560
uniprot id: A0A2K4BTT6
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

29379:I6G39 RS00120
gene id: 29379:I6G39_RS00120
uniprot id: A0A2K4C221
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS04830
gene id: 29379:I6G39_RS04830
uniprot id: A0A2K4C404
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

29379:I6G39 RS02795
gene id: 29379:I6G39_RS02795
uniprot id: A0A2K4C0A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

29379:I6G39 RS05655
gene id: 29379:I6G39_RS05655
uniprot id: A0A2K4BUV8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

29379:I6G39 RS07200
gene id: 29379:I6G39_RS07200
uniprot id: A0A2K4BZ47
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

29379:I6G39 RS08840
gene id: 29379:I6G39_RS08840
uniprot id: A0A2K4BYX2
names: Subcellular Location Annotation
messages: Cytoplasm

29379:I6G39 RS01865
gene id: 29379:I6G39_RS01865
uniprot id: A0A2K4BZV2
names: Similarity
messages: Belongs to the DCK/DGK family.

29379:I6G39 RS05825
gene id: 29379:I6G39_RS05825
uniprot id: A0A2K4BUX7
names: Similarity
messages: Belongs to the UPF0045 family.

29379:I6G39 RS05220
gene id: 29379:I6G39_RS05220
uniprot id: A0A2K4C112
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS08370
gene id: 29379:I6G39_RS08370
uniprot id: A0A2X5AAF5
names: Similarity
messages: Belongs to the acyltransferase 3 family.

29379:I6G39 RS09180
gene id: 29379:I6G39_RS09180
uniprot id: A0A2K4C4F4
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS02960
gene id: 29379:I6G39_RS02960
uniprot id: A0A2K4C070
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

29379:I6G39 RS03625
gene id: 29379:I6G39_RS03625
uniprot id: A0A2K4C4W9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system. Labile antitoxin that binds to cognate MazF toxin and counteracts its endoribonuclease activity.
messages: Belongs to the MazE/EndoAI family.

29379:I6G39 RS02890
gene id: 29379:I6G39_RS02890
uniprot id: A0A2K4C0A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

29379:I6G39 RS04105
gene id: 29379:I6G39_RS04105
uniprot id: A0A2K4BZR2
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS01275
gene id: 29379:I6G39_RS01275
uniprot id: A0A2K4BW27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

29379:I6G39 RS02230
gene id: 29379:I6G39_RS02230
uniprot id: A0A2K4C0M7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS00550
gene id: 29379:I6G39_RS00550
uniprot id: A0A2K4BTV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

29379:I6G39 RS03780
gene id: 29379:I6G39_RS03780
uniprot id: A0A2K4C2D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

29379:I6G39 RS07405
gene id: 29379:I6G39_RS07405
uniprot id: A0A2K4C368
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

29379:I6G39 RS03660
gene id: 29379:I6G39_RS03660
uniprot id: A0A2K4C3K6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

29379:I6G39 RS05890
gene id: 29379:I6G39_RS05890
uniprot id: A0A2K4BUZ2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the octanoyltransferase LipM family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation.
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. The reaction proceeds via an octanoyl-thioester enzyme intermediate.
messages: Monomer.

29379:I6G39 RS07515
gene id: 29379:I6G39_RS07515
uniprot id: A0A2K4C345
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

29379:I6G39 RS02660
gene id: 29379:I6G39_RS02660
uniprot id: A0A2K4C0D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS02330
gene id: 29379:I6G39_RS02330
uniprot id: A0A2K4C0J6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

29379:I6G39 RS09425
gene id: 29379:I6G39_RS09425
uniprot id: A0A2K4C144
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS01690
gene id: 29379:I6G39_RS01690
uniprot id: A0A2K4BYD2
names: Similarity
messages: Belongs to the ycf81 family.

29379:I6G39 RS05495
gene id: 29379:I6G39_RS05495
uniprot id: A0A2K4BUT0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

29379:I6G39 RS02500
gene id: 29379:I6G39_RS02500
uniprot id: A0A2K4C0H3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

29379:I6G39 RS07590
gene id: 29379:I6G39_RS07590
uniprot id: A0A2K4BU61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

29379:I6G39 RS05165
gene id: 29379:I6G39_RS05165
uniprot id: A0A2K4C0Y4
names: Similarity
messages: Belongs to the citrate synthase family.

29379:I6G39 RS08155
gene id: 29379:I6G39_RS08155
uniprot id: A0A2K4C250
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

29379:I6G39 RS01545
gene id: 29379:I6G39_RS01545
uniprot id: A0A2K4BYV3
names: Similarity
names: Subunit
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.
messages: Homodimer.

29379:I6G39 RS03315
gene id: 29379:I6G39_RS03315
uniprot id: A0A2K4C3Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

29379:I6G39 RS08580
gene id: 29379:I6G39_RS08580
uniprot id: A0A2K4C4X3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
messages: Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS02800
gene id: 29379:I6G39_RS02800
uniprot id: A0A2K4C099
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

29379:I6G39 RS05570
gene id: 29379:I6G39_RS05570
uniprot id: A0A2K4BUU3
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

29379:I6G39 RS01740
gene id: 29379:I6G39_RS01740
uniprot id: A0A2K4BYC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

29379:I6G39 RS01045
gene id: 29379:I6G39_RS01045
uniprot id: A0A2K4BVE4
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

29379:I6G39 RS04195
gene id: 29379:I6G39_RS04195
uniprot id: A0A2K4BZT1
names: Similarity
messages: Belongs to the UPF0421 family.

29379:I6G39 RS07300
gene id: 29379:I6G39_RS07300
uniprot id: A0A2K4C389
names: Function
names: Similarity
messages: Belongs to the asp23 family.
messages: May play a key role in alkaline pH tolerance.

29379:I6G39 RS05265
gene id: 29379:I6G39_RS05265
uniprot id: A0A2K4C292
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

29379:I6G39 RS02680
gene id: 29379:I6G39_RS02680
uniprot id: A0A2K4C0B1
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS03400
gene id: 29379:I6G39_RS03400
uniprot id: A0A2K4C523
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

29379:I6G39 RS05390
gene id: 29379:I6G39_RS05390
uniprot id: A0A2K4BWZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

29379:I6G39 RS00600
gene id: 29379:I6G39_RS00600
uniprot id: A0A2K4BTS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

29379:I6G39 RS00625
gene id: 29379:I6G39_RS00625
uniprot id: A0A2K4C1Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

29379:I6G39 RS05395
gene id: 29379:I6G39_RS05395
uniprot id: A0A2X5D7B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

29379:I6G39 RS09720
gene id: 29379:I6G39_RS09720
uniprot id: A0A2K4BZ21
names: Similarity
messages: Belongs to the TRAP family.

29379:I6G39 RS06000
gene id: 29379:I6G39_RS06000
uniprot id: A0A2K4BV37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

29379:I6G39 RS00925
gene id: 29379:I6G39_RS00925
uniprot id: A0A2K4BVF6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

29379:I6G39 RS00495
gene id: 29379:I6G39_RS00495
uniprot id: A0A2K4BTW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

29379:I6G39 RS08965
gene id: 29379:I6G39_RS08965
uniprot id: A0A2K4C4F3
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

29379:I6G39 RS08285
gene id: 29379:I6G39_RS08285
uniprot id: A0A2K4BWK0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

29379:I6G39 RS03410
gene id: 29379:I6G39_RS03410
uniprot id: A0A2K4C3T1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

29379:I6G39 RS09475
gene id: 29379:I6G39_RS09475
uniprot id: A0A2K4BXE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

29379:I6G39 RS08995
gene id: 29379:I6G39_RS08995
uniprot id: A0A2K4C4E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

29379:I6G39 RS00175
gene id: 29379:I6G39_RS00175
uniprot id: A0A2K4BXK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

29379:I6G39 RS09305
gene id: 29379:I6G39_RS09305
uniprot id: A0A2K4BUD2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS04630
gene id: 29379:I6G39_RS04630
uniprot id: A0A2K4BWR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.

29379:I6G39 RS03745
gene id: 29379:I6G39_RS03745
uniprot id: A0A2K4C2B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

29379:I6G39 RS05755
gene id: 29379:I6G39_RS05755
uniprot id: A0A2K4BUX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

29379:I6G39 RS00975
gene id: 29379:I6G39_RS00975
uniprot id: A0A2K4BVF3
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS10400
gene id: 29379:I6G39_RS10400
uniprot id: A0A2K4C1C0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

29379:I6G39 RS09155
gene id: 29379:I6G39_RS09155
uniprot id: A0A2K4C4A8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

29379:I6G39 RS05650
gene id: 29379:I6G39_RS05650
uniprot id: A0A2K4BUW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

29379:I6G39 RS08085
gene id: 29379:I6G39_RS08085
uniprot id: A0A2K4C2C3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

29379:I6G39 RS09150
gene id: 29379:I6G39_RS09150
uniprot id: A0A2K4C4B2
names: Function
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides.

29379:I6G39 RS02815
gene id: 29379:I6G39_RS02815
uniprot id: A0A2K4C0A7
names: Similarity
messages: Belongs to the MoaD family.

29379:I6G39 RS06820
gene id: 29379:I6G39_RS06820
uniprot id: A0A2K4C4Y7
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

29379:I6G39 RS03730
gene id: 29379:I6G39_RS03730
uniprot id: A0A2K4C2C1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS07925
gene id: 29379:I6G39_RS07925
uniprot id: A0A2K4BV82
names: Similarity
messages: Belongs to the SAICAR synthetase family.

29379:I6G39 RS05375
gene id: 29379:I6G39_RS05375
uniprot id: A0A2K4BX01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

29379:I6G39 RS02240
gene id: 29379:I6G39_RS02240
uniprot id: A0A2K4C0K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

29379:I6G39 RS02470
gene id: 29379:I6G39_RS02470
uniprot id: A0A2K4C0F4
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

29379:I6G39 RS04015
gene id: 29379:I6G39_RS04015
uniprot id: A0A2K4BZQ0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

29379:I6G39 RS08575
gene id: 29379:I6G39_RS08575
uniprot id: A0A2K4C6A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell membrane
messages: Membrane
messages: O-acyltransferase that catalyzes D-alanylation of both teichoic acid and lipoteichoic acid (LTA). D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Catalyzes D-alanylation from DltC carrier protein.

29379:I6G39 RS03595
gene id: 29379:I6G39_RS03595
uniprot id: A0A2K4C3L0
names: Similarity
messages: Belongs to the DEAD box helicase family.

29379:I6G39 RS03655
gene id: 29379:I6G39_RS03655
uniprot id: A0A2K4C3Q6
names: Function
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

29379:I6G39 RS01120
gene id: 29379:I6G39_RS01120
uniprot id: A0A2K4BVB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

29379:I6G39 RS08005
gene id: 29379:I6G39_RS08005
uniprot id: A0A2K4C1E0
names: Subcellular Location Annotation
messages: Cell membrane

29379:I6G39 RS05675
gene id: 29379:I6G39_RS05675
uniprot id: A0A2K4BUV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

29379:I6G39 RS06290
gene id: 29379:I6G39_RS06290
uniprot id: A0A2K4C2X3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

29379:I6G39 RS03460
gene id: 29379:I6G39_RS03460
uniprot id: A0A2K4C3R7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29379:I6G39 RS01555
gene id: 29379:I6G39_RS01555
uniprot id: A0A2K4BYW8
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. Can also catalyze the epimerization of carbon 2' of dihydroneopterin to dihydromonapterin.

29379:I6G39 RS01150
gene id: 29379:I6G39_RS01150
uniprot id: A0A2K4BWL6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

29379:I6G39 RS06505
gene id: 29379:I6G39_RS06505
uniprot id: A0A2K4BWV0
names: Similarity
messages: Belongs to the acylphosphatase family.

29379:I6G39 RS06375
gene id: 29379:I6G39_RS06375
uniprot id: A0A2K4C301
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

29379:I6G39 RS09470
gene id: 29379:I6G39_RS09470
uniprot id: A0A2K4BXC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

29379:I6G39 RS03310
gene id: 29379:I6G39_RS03310
uniprot id: A0A2K4C3Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

29379:I6G39 RS05015
gene id: 29379:I6G39_RS05015
uniprot id: A0A2K4BY88
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS04125
gene id: 29379:I6G39_RS04125
uniprot id: A0A2K4C151
names: Similarity
messages: Belongs to the peptidase M29 family.

29379:I6G39 RS06985
gene id: 29379:I6G39_RS06985
uniprot id: A0A2K4C4P7
names: Similarity
messages: Belongs to the CinA family.

29379:I6G39 RS05790
gene id: 29379:I6G39_RS05790
uniprot id: A0A2K4BUY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fur family.
messages: Cytoplasm

29379:I6G39 RS02605
gene id: 29379:I6G39_RS02605
uniprot id: A0A2K4C0E7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

29379:I6G39 RS08495
gene id: 29379:I6G39_RS08495
uniprot id: A0A2K4C2R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS04540
gene id: 29379:I6G39_RS04540
uniprot id: A0A2K4BWQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

29379:I6G39 RS07210
gene id: 29379:I6G39_RS07210
uniprot id: A0A2K4BZ31
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

29379:I6G39 RS06045
gene id: 29379:I6G39_RS06045
uniprot id: A0A2K4BV20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fur family.
messages: Cytoplasm

29379:I6G39 RS07435
gene id: 29379:I6G39_RS07435
uniprot id: A0A2K4C342
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

29379:I6G39 RS01520
gene id: 29379:I6G39_RS01520
uniprot id: A0A2K4BYW9
names: Function
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

29379:I6G39 RS01765
gene id: 29379:I6G39_RS01765
uniprot id: A0A2K4BYA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

29379:I6G39 RS08990
gene id: 29379:I6G39_RS08990
uniprot id: A0A2K4C4E6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

29379:I6G39 RS05105
gene id: 29379:I6G39_RS05105
uniprot id: A0A2K4BVU9
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer.

29379:I6G39 RS01065
gene id: 29379:I6G39_RS01065
uniprot id: A0A2K4BVD5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS09935
gene id: 29379:I6G39_RS09935
uniprot id: A0A2K4BYF8
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

29379:I6G39 RS06125
gene id: 29379:I6G39_RS06125
uniprot id: A0A2K4BV39
names: Function
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

29379:I6G39 RS02765
gene id: 29379:I6G39_RS02765
uniprot id: A0A2K4C0C2
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

29379:I6G39 RS07430
gene id: 29379:I6G39_RS07430
uniprot id: A0A2K4C394
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

29379:I6G39 RS07585
gene id: 29379:I6G39_RS07585
uniprot id: A0A2K4BU69
names: Function
names: Similarity
messages: Belongs to the thioredoxin family.
messages: Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.

29379:I6G39 RS06520
gene id: 29379:I6G39_RS06520
uniprot id: A0A2K4BWV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

29379:I6G39 RS09000
gene id: 29379:I6G39_RS09000
uniprot id: A0A2K4C4D3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

29379:I6G39 RS01570
gene id: 29379:I6G39_RS01570
uniprot id: A0A2K4BYX8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

29379:I6G39 RS01430
gene id: 29379:I6G39_RS01430
uniprot id: A0A2K4C082
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS07920
gene id: 29379:I6G39_RS07920
uniprot id: A0A2K4BU04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

29379:I6G39 RS01095
gene id: 29379:I6G39_RS01095
uniprot id: A0A2K4BVC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer; disulfide-linked, upon oxidation. 5 homodimers assemble to form a ring-like decamer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

29379:I6G39 RS06275
gene id: 29379:I6G39_RS06275
uniprot id: A0A2K4C343
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

29379:I6G39 RS01485
gene id: 29379:I6G39_RS01485
uniprot id: A0A2K4BYX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

29379:I6G39 RS03070
gene id: 29379:I6G39_RS03070
uniprot id: A0A2K4C050
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

29379:I6G39 RS09485
gene id: 29379:I6G39_RS09485
uniprot id: A0A2K4BXD3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

29379:I6G39 RS07785
gene id: 29379:I6G39_RS07785
uniprot id: A0A2K4BU33
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes.
messages: Membrane
messages: The active site is a redox-active disulfide bond.

29379:I6G39 RS05425
gene id: 29379:I6G39_RS05425
uniprot id: A0A2K4BWZ1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp.

29379:I6G39 RS05475
gene id: 29379:I6G39_RS05475
uniprot id: A0A2K4BVZ9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

29379:I6G39 RS00195
gene id: 29379:I6G39_RS00195
uniprot id: A0A2K4BWA5
names: Similarity
messages: Belongs to the EfeM/EfeO family.

29379:I6G39 RS07565
gene id: 29379:I6G39_RS07565
uniprot id: A0A2K4BVE9
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

29379:I6G39 RS10360
gene id: 29379:I6G39_RS10360
uniprot id: A0A2K4C203
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS03580
gene id: 29379:I6G39_RS03580
uniprot id: A0A2K4C3J4
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS09750
gene id: 29379:I6G39_RS09750
uniprot id: A0A2K4BXS9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

29379:I6G39 RS00910
gene id: 29379:I6G39_RS00910
uniprot id: A0A2K4BVG3
names: Subcellular Location Annotation
messages: cell wall

29379:I6G39 RS01455
gene id: 29379:I6G39_RS01455
uniprot id: A0A2K4BYV7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

29379:I6G39 RS03220
gene id: 29379:I6G39_RS03220
uniprot id: A0A2K4C3U2
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

29379:I6G39 RS03920
gene id: 29379:I6G39_RS03920
uniprot id: A0A2K4BZP5
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

29379:I6G39 RS06165
gene id: 29379:I6G39_RS06165
uniprot id: A0A2K4BWY5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

29379:I6G39 RS05935
gene id: 29379:I6G39_RS05935
uniprot id: A0A2K4BUZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

29379:I6G39 RS00635
gene id: 29379:I6G39_RS00635
uniprot id: A0A2K4C1Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

29379:I6G39 RS07915
gene id: 29379:I6G39_RS07915
uniprot id: A0A2K4BU00
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

29379:I6G39 RS10185
gene id: 29379:I6G39_RS10185
uniprot id: A0A2K4BXF8
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

29379:I6G39 RS06695
gene id: 29379:I6G39_RS06695
uniprot id: A0A2K4C1M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

29379:I6G39 RS07975
gene id: 29379:I6G39_RS07975
uniprot id: A0A2K4C2K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS06515
gene id: 29379:I6G39_RS06515
uniprot id: A0A2K4BWW7
names: Subcellular Location Annotation
messages: Cytoplasm

29379:I6G39 RS09580
gene id: 29379:I6G39_RS09580
uniprot id: A0A2K4C1L6
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

29379:I6G39 RS06800
gene id: 29379:I6G39_RS06800
uniprot id: A0A2K4C4S0
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS04820
gene id: 29379:I6G39_RS04820
uniprot id: A0A2K4C469
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

29379:I6G39 RS02820
gene id: 29379:I6G39_RS02820
uniprot id: A0A2K4C076
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

29379:I6G39 RS08365
gene id: 29379:I6G39_RS08365
uniprot id: A0A2K4C454
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

29379:I6G39 RS01665
gene id: 29379:I6G39_RS01665
uniprot id: A0A2K4BYC7
names: Function
names: Similarity
messages: Belongs to the CtsR family.
messages: Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.

29379:I6G39 RS02985
gene id: 29379:I6G39_RS02985
uniprot id: A0A2K4C047
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

29379:I6G39 RS00230
gene id: 29379:I6G39_RS00230
uniprot id: A0A2K4BWB9
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS09095
gene id: 29379:I6G39_RS09095
uniprot id: A0A2K4C4C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

29379:I6G39 RS04565
gene id: 29379:I6G39_RS04565
uniprot id: A0A2K4BWS2
names: Similarity
messages: Belongs to the UPF0754 family.

29379:I6G39 RS06305
gene id: 29379:I6G39_RS06305
uniprot id: A0A2K4C496
names: Subcellular Location Annotation
messages: Cytoplasm

29379:I6G39 RS00885
gene id: 29379:I6G39_RS00885
uniprot id: A0A2K4BVH4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

29379:I6G39 RS08735
gene id: 29379:I6G39_RS08735
uniprot id: A0A2K4BZF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

29379:I6G39 RS07285
gene id: 29379:I6G39_RS07285
uniprot id: A0A2K4C370
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

29379:I6G39 RS04190
gene id: 29379:I6G39_RS04190
uniprot id: A0A2K4BZU9
names: Function
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.

29379:I6G39 RS07030
gene id: 29379:I6G39_RS07030
uniprot id: A0A2K4C4P4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

29379:I6G39 RS07550
gene id: 29379:I6G39_RS07550
uniprot id: A0A2K4BU95
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

29379:I6G39 RS00720
gene id: 29379:I6G39_RS00720
uniprot id: A0A2K4BVN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. HrtA family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (HrtA), two transmembrane proteins (HrtB) and a solute-binding protein.

29379:I6G39 RS03235
gene id: 29379:I6G39_RS03235
uniprot id: A0A2K4C550
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

29379:I6G39 RS06175
gene id: 29379:I6G39_RS06175
uniprot id: A0A2K4BWX5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

29379:I6G39 RS05275
gene id: 29379:I6G39_RS05275
uniprot id: A0A2K4C105
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS10045
gene id: 29379:I6G39_RS10045
uniprot id: A0A2K4BZ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

29379:I6G39 RS07580
gene id: 29379:I6G39_RS07580
uniprot id: A0A2K4BU73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

29379:I6G39 RS10080
gene id: 29379:I6G39_RS10080
uniprot id: A0A2K4BUP3
names: Similarity
messages: Belongs to the universal stress protein A family.

29379:I6G39 RS03425
gene id: 29379:I6G39_RS03425
uniprot id: A0A2K4C3P1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

29379:I6G39 RS07485
gene id: 29379:I6G39_RS07485
uniprot id: A0A2K4C387
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

29379:I6G39 RS03770
gene id: 29379:I6G39_RS03770
uniprot id: A0A2K4C2G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

29379:I6G39 RS08065
gene id: 29379:I6G39_RS08065
uniprot id: A0A2K4C2B7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

29379:I6G39 RS09030
gene id: 29379:I6G39_RS09030
uniprot id: A0A2K4C4B5
names: Function
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

29379:I6G39 RS01790
gene id: 29379:I6G39_RS01790
uniprot id: A0A2K4BYB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

29379:I6G39 RS07170
gene id: 29379:I6G39_RS07170
uniprot id: A0A2K4C0J8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

29379:I6G39 RS02385
gene id: 29379:I6G39_RS02385
uniprot id: A0A2K4C0J1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS09550
gene id: 29379:I6G39_RS09550
uniprot id: A0A2K4C1I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS05440
gene id: 29379:I6G39_RS05440
uniprot id: A0A2K4BWY4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

29379:I6G39 RS03885
gene id: 29379:I6G39_RS03885
uniprot id: A0A2K4BY03
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS08170
gene id: 29379:I6G39_RS08170
uniprot id: A0A2K4C279
names: Subcellular Location Annotation
messages: Cell membrane

29379:I6G39 RS00755
gene id: 29379:I6G39_RS00755
uniprot id: A0A2K4BVQ0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

29379:I6G39 RS03695
gene id: 29379:I6G39_RS03695
uniprot id: A0A2K4C2A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

29379:I6G39 RS03045
gene id: 29379:I6G39_RS03045
uniprot id: A0A2K4C1I0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS03995
gene id: 29379:I6G39_RS03995
uniprot id: A0A2K4BZP1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

29379:I6G39 RS00540
gene id: 29379:I6G39_RS00540
uniprot id: A0A2K4BTW3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

29379:I6G39 RS06610
gene id: 29379:I6G39_RS06610
uniprot id: A0A2K4C309
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

29379:I6G39 RS07860
gene id: 29379:I6G39_RS07860
uniprot id: A0A2K4BU10
names: Subcellular Location Annotation
messages: Cell membrane

29379:I6G39 RS00185
gene id: 29379:I6G39_RS00185
uniprot id: A0A2K4BWA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

29379:I6G39 RS01685
gene id: 29379:I6G39_RS01685
uniprot id: A0A2K4BYE2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

29379:I6G39 RS07100
gene id: 29379:I6G39_RS07100
uniprot id: A0A2K4C4N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

29379:I6G39 RS06915
gene id: 29379:I6G39_RS06915
uniprot id: A0A2K4C4R6
names: Function
messages: Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.

29379:I6G39 RS06595
gene id: 29379:I6G39_RS06595
uniprot id: A0A2K4C1P6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

29379:I6G39 RS06215
gene id: 29379:I6G39_RS06215
uniprot id: A0A2K4C2V8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

29379:I6G39 RS03535
gene id: 29379:I6G39_RS03535
uniprot id: A0A2K4C3S7
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

29379:I6G39 RS05530
gene id: 29379:I6G39_RS05530
uniprot id: A0A2K4BW07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

29379:I6G39 RS01495
gene id: 29379:I6G39_RS01495
uniprot id: A0A2K4BYX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

29379:I6G39 RS03720
gene id: 29379:I6G39_RS03720
uniprot id: A0A2K4C2B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

29379:I6G39 RS03405
gene id: 29379:I6G39_RS03405
uniprot id: A0A2K4C3M1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

29379:I6G39 RS05140
gene id: 29379:I6G39_RS05140
uniprot id: A0A2K4C128
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

29379:I6G39 RS03750
gene id: 29379:I6G39_RS03750
uniprot id: A0A2K4C2B4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

29379:I6G39 RS10195
gene id: 29379:I6G39_RS10195
uniprot id: A0A2K4BXG4
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS10140
gene id: 29379:I6G39_RS10140
uniprot id: A0A2K4BXF9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS07990
gene id: 29379:I6G39_RS07990
uniprot id: A0A2K4C192
names: Similarity
messages: Belongs to the LacAB/RpiB family.

29379:I6G39 RS10085
gene id: 29379:I6G39_RS10085
uniprot id: A0A2K4BY01
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS08895
gene id: 29379:I6G39_RS08895
uniprot id: A0A2K4BYY4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

29379:I6G39 RS03150
gene id: 29379:I6G39_RS03150
uniprot id: A0A2K4BY53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

29379:I6G39 RS07260
gene id: 29379:I6G39_RS07260
uniprot id: A0A2K4C3C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

29379:I6G39 RS07160
gene id: 29379:I6G39_RS07160
uniprot id: A0A2K4C5Y8
names: Similarity
messages: Belongs to the DprA/Smf family.

29379:I6G39 RS07820
gene id: 29379:I6G39_RS07820
uniprot id: A0A2K4BV96
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

29379:I6G39 RS09145
gene id: 29379:I6G39_RS09145
uniprot id: A0A2K4C4E1
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

29379:I6G39 RS05960
gene id: 29379:I6G39_RS05960
uniprot id: A0A2K4BWA2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes.
messages: Membrane
messages: The active site is a redox-active disulfide bond.

29379:I6G39 RS07880
gene id: 29379:I6G39_RS07880
uniprot id: A0A2K4BU09
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS08355
gene id: 29379:I6G39_RS08355
uniprot id: A0A2K4C2T1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

29379:I6G39 RS01525
gene id: 29379:I6G39_RS01525
uniprot id: A0A2K4BYX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.

29379:I6G39 RS00590
gene id: 29379:I6G39_RS00590
uniprot id: A0A2X4ZVY1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

29379:I6G39 RS01760
gene id: 29379:I6G39_RS01760
uniprot id: A0A2K4BZP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

29379:I6G39 RS04530
gene id: 29379:I6G39_RS04530
uniprot id: A0A2K4BWQ0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

29379:I6G39 RS01675
gene id: 29379:I6G39_RS01675
uniprot id: A0A2K4BYF1
names: Caution
names: Function
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS09680
gene id: 29379:I6G39_RS09680
uniprot id: A0A2K4C1E5
names: Similarity
messages: Belongs to the FBPase class 3 family.

29379:I6G39 RS03970
gene id: 29379:I6G39_RS03970
uniprot id: A0A2K4BZM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS02225
gene id: 29379:I6G39_RS02225
uniprot id: A0A2K4C2L7
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS01460
gene id: 29379:I6G39_RS01460
uniprot id: A0A2K4BYV1
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

29379:I6G39 RS07780
gene id: 29379:I6G39_RS07780
uniprot id: A0A2K4BU68
names: Similarity
messages: Belongs to the UPF0223 family.

29379:I6G39 RS01445
gene id: 29379:I6G39_RS01445
uniprot id: A0A2K4BYW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
messages: This protein produces a dimethylation of the adenine residue at position 2085 in 23S rRNA, resulting in reduced affinity between ribosomes and macrolide-lincosamide-streptogramin B antibiotics.

29379:I6G39 RS01440
gene id: 29379:I6G39_RS01440
uniprot id: A0A2K4BYT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

29379:I6G39 RS05785
gene id: 29379:I6G39_RS05785
uniprot id: A0A2K4BUX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS01490
gene id: 29379:I6G39_RS01490
uniprot id: A0A2K4BYU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

29379:I6G39 RS07980
gene id: 29379:I6G39_RS07980
uniprot id: A0A2X5ADW5
names: Function
messages: Repressor of the lactose catabolism operon. Galactose-6-phosphate is the inducer.

29379:I6G39 RS01640
gene id: 29379:I6G39_RS01640
uniprot id: A0A2K4BYE1
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

29379:I6G39 RS10300
gene id: 29379:I6G39_RS10300
uniprot id: A0A2K4C1X9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

29379:I6G39 RS02070
gene id: 29379:I6G39_RS02070
uniprot id: A0A2K4C2P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

29379:I6G39 RS05315
gene id: 29379:I6G39_RS05315
uniprot id: A0A2K4C282
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

29379:I6G39 RS04115
gene id: 29379:I6G39_RS04115
uniprot id: A0A2K4BZS3
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

29379:I6G39 RS04835
gene id: 29379:I6G39_RS04835
uniprot id: A0A2K4C411
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS01110
gene id: 29379:I6G39_RS01110
uniprot id: A0A2K4BVC1
names: Function
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.
messages: Reduces FMN, organic nitro compounds and disulfide DTNB. Involved in maintenance of the cellular redox state and the disulfide stress response.

29379:I6G39 RS01980
gene id: 29379:I6G39_RS01980
uniprot id: A0A2K4C2M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

29379:I6G39 RS04200
gene id: 29379:I6G39_RS04200
uniprot id: A0A2K4BZT0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

29379:I6G39 RS06545
gene id: 29379:I6G39_RS06545
uniprot id: A0A2K4BWU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homodimer.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

29379:I6G39 RS02565
gene id: 29379:I6G39_RS02565
uniprot id: A0A2K4C1Q9
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS01955
gene id: 29379:I6G39_RS01955
uniprot id: A0A2K4C3Z7
names: Similarity
messages: Belongs to the ThiD family.

29379:I6G39 RS09495
gene id: 29379:I6G39_RS09495
uniprot id: A0A2K4BXB1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS06350
gene id: 29379:I6G39_RS06350
uniprot id: A0A2K4C330
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

29379:I6G39 RS10150
gene id: 29379:I6G39_RS10150
uniprot id: A0A2K4BXE9
names: Subcellular Location Annotation
messages: Cell membrane

29379:I6G39 RS06660
gene id: 29379:I6G39_RS06660
uniprot id: A0A2K4C2Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

29379:I6G39 RS09595
gene id: 29379:I6G39_RS09595
uniprot id: A0A2K4C1L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS07125
gene id: 29379:I6G39_RS07125
uniprot id: A0A2K4C4M4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

29379:I6G39 RS05465
gene id: 29379:I6G39_RS05465
uniprot id: A0A2K4BUR1
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

29379:I6G39 RS02655
gene id: 29379:I6G39_RS02655
uniprot id: A0A2K4C0D1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

29379:I6G39 RS00760
gene id: 29379:I6G39_RS00760
uniprot id: A0A2K4BVQ9
names: Similarity
messages: Belongs to the ParB family.

29379:I6G39 RS07475
gene id: 29379:I6G39_RS07475
uniprot id: A0A2K4C4F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

29379:I6G39 RS01385
gene id: 29379:I6G39_RS01385
uniprot id: A0A2K4BYV4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

29379:I6G39 RS00650
gene id: 29379:I6G39_RS00650
uniprot id: A0A2K4C1R0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.

29379:I6G39 RS02115
gene id: 29379:I6G39_RS02115
uniprot id: A0A2K4C2N4
names: Similarity
messages: Belongs to the FGGY kinase family.

29379:I6G39 RS04785
gene id: 29379:I6G39_RS04785
uniprot id: A0A2K4C400
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

29379:I6G39 RS09335
gene id: 29379:I6G39_RS09335
uniprot id: A0A2K4C148
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS03280
gene id: 29379:I6G39_RS03280
uniprot id: A0A2K4C3S0
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

29379:I6G39 RS03540
gene id: 29379:I6G39_RS03540
uniprot id: A0A2K4C3S6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

29379:I6G39 RS01870
gene id: 29379:I6G39_RS01870
uniprot id: A0A2K4BZU8
names: Similarity
messages: Belongs to the DCK/DGK family.

29379:I6G39 RS06025
gene id: 29379:I6G39_RS06025
uniprot id: A0A2K4BV17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

29379:I6G39 RS09390
gene id: 29379:I6G39_RS09390
uniprot id: A0A2K4C146
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS07320
gene id: 29379:I6G39_RS07320
uniprot id: A0A2K4C365
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

29379:I6G39 RS00630
gene id: 29379:I6G39_RS00630
uniprot id: A0A2K4C1V4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

29379:I6G39 RS07705
gene id: 29379:I6G39_RS07705
uniprot id: A0A2K4BU32
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS04505
gene id: 29379:I6G39_RS04505
uniprot id: A0A2K4BWR0
names: Similarity
messages: Belongs to the CvfC family.

29379:I6G39 RS07045
gene id: 29379:I6G39_RS07045
uniprot id: A0A2K4C4N7
names: Similarity
messages: Belongs to the ribF family.

29379:I6G39 RS07970
gene id: 29379:I6G39_RS07970
uniprot id: A0A2K4C183
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS02615
gene id: 29379:I6G39_RS02615
uniprot id: A0A2K4C0E9
names: Function
messages: Repressor of the lactose catabolism operon. Galactose-6-phosphate is the inducer.

29379:I6G39 RS05285
gene id: 29379:I6G39_RS05285
uniprot id: A0A2K4C0W1
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

29379:I6G39 RS02630
gene id: 29379:I6G39_RS02630
uniprot id: A0A2K4C0B9
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

29379:I6G39 RS04735
gene id: 29379:I6G39_RS04735
uniprot id: A0A2K4C3Y8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

29379:I6G39 RS06265
gene id: 29379:I6G39_RS06265
uniprot id: A0A2K4C2X1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

29379:I6G39 RS02100
gene id: 29379:I6G39_RS02100
uniprot id: A0A2K4C2P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

29379:I6G39 RS03075
gene id: 29379:I6G39_RS03075
uniprot id: A0A2K4C048
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS05770
gene id: 29379:I6G39_RS05770
uniprot id: A0A2K4BUW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. CshB subfamily.
messages: Cytoplasm
messages: Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.

29379:I6G39 RS09020
gene id: 29379:I6G39_RS09020
uniprot id: A0A2K4C4H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

29379:I6G39 RS05120
gene id: 29379:I6G39_RS05120
uniprot id: A0A2K4BVU4
names: Similarity
messages: Belongs to the universal stress protein A family.

29379:I6G39 RS05480
gene id: 29379:I6G39_RS05480
uniprot id: A0A2K4BUS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

29379:I6G39 RS04975
gene id: 29379:I6G39_RS04975
uniprot id: A0A2K4C444
names: Function
names: Similarity
messages: Belongs to the histone deacetylase family.
messages: Role in growth on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source.

29379:I6G39 RS08275
gene id: 29379:I6G39_RS08275
uniprot id: A0A2K4BWH9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

29379:I6G39 RS09415
gene id: 29379:I6G39_RS09415
uniprot id: A0A2K4C184
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS01650
gene id: 29379:I6G39_RS01650
uniprot id: A0A2K4BYD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

29379:I6G39 RS01940
gene id: 29379:I6G39_RS01940
uniprot id: A0A2K4C2N5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

29379:I6G39 RS09270
gene id: 29379:I6G39_RS09270
uniprot id: A0A2K4C4A3
names: Function
messages: Repressor of the lactose catabolism operon. Galactose-6-phosphate is the inducer.

29379:I6G39 RS02310
gene id: 29379:I6G39_RS02310
uniprot id: A0A2K4C0I5
names: Similarity
messages: Belongs to the AHA1 family.

29379:I6G39 RS10145
gene id: 29379:I6G39_RS10145
uniprot id: A0A2K4BXG6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS02970
gene id: 29379:I6G39_RS02970
uniprot id: A0A2K4C068
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

29379:I6G39 RS05310
gene id: 29379:I6G39_RS05310
uniprot id: A0A2K4C0Y6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

29379:I6G39 RS05680
gene id: 29379:I6G39_RS05680
uniprot id: A0A2K4BUW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

29379:I6G39 RS01480
gene id: 29379:I6G39_RS01480
uniprot id: A0A2K4C092
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

29379:I6G39 RS05355
gene id: 29379:I6G39_RS05355
uniprot id: A0A2K4BWZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

29379:I6G39 RS09045
gene id: 29379:I6G39_RS09045
uniprot id: A0A2K4C4D4
names: Similarity
messages: Belongs to the IMPACT family.

29379:I6G39 RS09500
gene id: 29379:I6G39_RS09500
uniprot id: A0A2K4BXC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

29379:I6G39 RS05160
gene id: 29379:I6G39_RS05160
uniprot id: A0A2K4C2A9
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS02090
gene id: 29379:I6G39_RS02090
uniprot id: A0A2K4C2Q8
names: Subcellular Location Annotation
messages: Cell membrane

29379:I6G39 RS00795
gene id: 29379:I6G39_RS00795
uniprot id: A0A2K4BVP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

29379:I6G39 RS02715
gene id: 29379:I6G39_RS02715
uniprot id: A0A2K4C098
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS03155
gene id: 29379:I6G39_RS03155
uniprot id: A0A2K4BY17
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS03485
gene id: 29379:I6G39_RS03485
uniprot id: A0A2K4C3N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

29379:I6G39 RS07280
gene id: 29379:I6G39_RS07280
uniprot id: A0A2K4C371
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

29379:I6G39 RS02400
gene id: 29379:I6G39_RS02400
uniprot id: A0A2K4C0G0
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

29379:I6G39 RS04825
gene id: 29379:I6G39_RS04825
uniprot id: A0A2K4C402
names: Cofactor
messages: Binds 1 FAD per subunit.

29379:I6G39 RS08090
gene id: 29379:I6G39_RS08090
uniprot id: A0A2K4C267
names: Similarity
messages: Belongs to the isochorismate synthase family.

29379:I6G39 RS00240
gene id: 29379:I6G39_RS00240
uniprot id: A0A2K4BWC3
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

29379:I6G39 RS10325
gene id: 29379:I6G39_RS10325
uniprot id: A0A2K4C228
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. HrtB subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (HrtA), two transmembrane proteins (HrtB) and a solute-binding protein.

29379:I6G39 RS08740
gene id: 29379:I6G39_RS08740
uniprot id: A0A2K4BZI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS06085
gene id: 29379:I6G39_RS06085
uniprot id: A0A2K4BV45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

29379:I6G39 RS10390
gene id: 29379:I6G39_RS10390
uniprot id: A0A2K4C1E9
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

29379:I6G39 RS10330
gene id: 29379:I6G39_RS10330
uniprot id: A0A2K4C1W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. HrtB subfamily.
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (HrtA), two transmembrane proteins (HrtB) and a solute-binding protein.

29379:I6G39 RS06735
gene id: 29379:I6G39_RS06735
uniprot id: A0A2K4C4X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

29379:I6G39 RS04375
gene id: 29379:I6G39_RS04375
uniprot id: A0A2K4BVY1
names: Similarity
messages: Belongs to the peptidase S14 family.

29379:I6G39 RS00340
gene id: 29379:I6G39_RS00340
uniprot id: A0A2K4BWD9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

29379:I6G39 RS01835
gene id: 29379:I6G39_RS01835
uniprot id: A0A2K4BYB0
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

29379:I6G39 RS10730
gene id: 29379:I6G39_RS10730
uniprot id: A0A2K4BYY1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

29379:I6G39 RS07355
gene id: 29379:I6G39_RS07355
uniprot id: A0A2K4C373
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

29379:I6G39 RS06675
gene id: 29379:I6G39_RS06675
uniprot id: A0A2K4C1M4
names: Similarity
messages: Belongs to the HesB/IscA family.

29379:I6G39 RS02490
gene id: 29379:I6G39_RS02490
uniprot id: A0A7T3A6N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

29379:I6G39 RS05915
gene id: 29379:I6G39_RS05915
uniprot id: A0A2K4BUZ7
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

29379:I6G39 RS03450
gene id: 29379:I6G39_RS03450
uniprot id: A0A2K4C510
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS01165
gene id: 29379:I6G39_RS01165
uniprot id: A0A2X5B0K2
names: Function
messages: Involved in the transposition of the insertion sequence.

29379:I6G39 RS07460
gene id: 29379:I6G39_RS07460
uniprot id: A0A2K4C352
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

29379:I6G39 RS10395
gene id: 29379:I6G39_RS10395
uniprot id: A0A2K4C1A5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

29379:I6G39 RS07555
gene id: 29379:I6G39_RS07555
uniprot id: A0A2K4BU67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

29379:I6G39 RS08480
gene id: 29379:I6G39_RS08480
uniprot id: A0A2K4C2Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS02825
gene id: 29379:I6G39_RS02825
uniprot id: A0A2K4C0B2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

29379:I6G39 RS03165
gene id: 29379:I6G39_RS03165
uniprot id: A0A2K4BZE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS01365
gene id: 29379:I6G39_RS01365
uniprot id: A0A2K4BW30
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

29379:I6G39 RS09125
gene id: 29379:I6G39_RS09125
uniprot id: A0A2K4C4G1
names: Similarity
messages: Belongs to the EamA transporter family.

29379:I6G39 RS00960
gene id: 29379:I6G39_RS00960
uniprot id: A0A2K4BVF4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

29379:I6G39 RS03960
gene id: 29379:I6G39_RS03960
uniprot id: A0A2K4BZM7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

29379:I6G39 RS04945
gene id: 29379:I6G39_RS04945
uniprot id: A0A2K4C426
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

29379:I6G39 RS07630
gene id: 29379:I6G39_RS07630
uniprot id: A0A2K4BU62
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

29379:I6G39 RS10335
gene id: 29379:I6G39_RS10335
uniprot id: A0A2K4C1W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. HrtA family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (HrtA), two transmembrane proteins (HrtB) and a solute-binding protein.

29379:I6G39 RS02895
gene id: 29379:I6G39_RS02895
uniprot id: A0A2K4C1L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

29379:I6G39 RS07050
gene id: 29379:I6G39_RS07050
uniprot id: A0A2K4C4Q0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

29379:I6G39 RS02335
gene id: 29379:I6G39_RS02335
uniprot id: A0A2K4C0H1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

29379:I6G39 RS05290
gene id: 29379:I6G39_RS05290
uniprot id: A0A2K4C0U2
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

29379:I6G39 RS03430
gene id: 29379:I6G39_RS03430
uniprot id: A0A2K4C3U8
names: Similarity
messages: Belongs to the UPF0340 family.

29379:I6G39 RS09560
gene id: 29379:I6G39_RS09560
uniprot id: A0A2K4C1G4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

29379:I6G39 RS08190
gene id: 29379:I6G39_RS08190
uniprot id: A0A2K4C232
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

29379:I6G39 RS05955
gene id: 29379:I6G39_RS05955
uniprot id: A0A2K4BV06
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

29379:I6G39 RS02940
gene id: 29379:I6G39_RS02940
uniprot id: A0A2K4C091
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

29379:I6G39 RS07085
gene id: 29379:I6G39_RS07085
uniprot id: A0A2K4C4M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

29379:I6G39 RS08410
gene id: 29379:I6G39_RS08410
uniprot id: A0A2K4C2X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Essential for cell viability.
messages: Membrane

29379:I6G39 RS02540
gene id: 29379:I6G39_RS02540
uniprot id: A0A2K4C0E6
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS02930
gene id: 29379:I6G39_RS02930
uniprot id: A0A2K4C089
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

29379:I6G39 RS06120
gene id: 29379:I6G39_RS06120
uniprot id: A0A2K4BV33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

29379:I6G39 RS08600
gene id: 29379:I6G39_RS08600
uniprot id: A0A2K4BUE1
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.

29379:I6G39 RS05505
gene id: 29379:I6G39_RS05505
uniprot id: A0A2K4BUS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

29379:I6G39 RS05035
gene id: 29379:I6G39_RS05035
uniprot id: A0A2K4BZL1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

29379:I6G39 RS05875
gene id: 29379:I6G39_RS05875
uniprot id: A0A2K4BV09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

29379:I6G39 RS00020
gene id: 29379:I6G39_RS00020
uniprot id: A0A2K4BUP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

29379:I6G39 RS00370
gene id: 29379:I6G39_RS00370
uniprot id: A0A2K4BWF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

29379:I6G39 RS05270
gene id: 29379:I6G39_RS05270
uniprot id: A0A2K4C0W7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

29379:I6G39 RS04805
gene id: 29379:I6G39_RS04805
uniprot id: A0A2K4C456
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

29379:I6G39 RS06690
gene id: 29379:I6G39_RS06690
uniprot id: A0A2K4C1Q8
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS02995
gene id: 29379:I6G39_RS02995
uniprot id: A0A2K4C1J0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

29379:I6G39 RS07845
gene id: 29379:I6G39_RS07845
uniprot id: A0A2K4BU15
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

29379:I6G39 RS06990
gene id: 29379:I6G39_RS06990
uniprot id: A0A2K4C4Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

29379:I6G39 RS01960
gene id: 29379:I6G39_RS01960
uniprot id: A0A2K4C2L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

29379:I6G39 RS09910
gene id: 29379:I6G39_RS09910
uniprot id: A0A2K4BYJ5
names: Similarity
messages: Belongs to the TPP enzyme family.

29379:I6G39 RS06015
gene id: 29379:I6G39_RS06015
uniprot id: A0A2K4BWB2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS06370
gene id: 29379:I6G39_RS06370
uniprot id: A0A2K4C2Z7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS07905
gene id: 29379:I6G39_RS07905
uniprot id: A0A2K4BU03
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

29379:I6G39 RS03980
gene id: 29379:I6G39_RS03980
uniprot id: A0A2K4BZQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
messages: Homodimer and homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

29379:I6G39 RS05225
gene id: 29379:I6G39_RS05225
uniprot id: A0A2K4C0V7
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS06570
gene id: 29379:I6G39_RS06570
uniprot id: A0A2K4C1T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

29379:I6G39 RS09800
gene id: 29379:I6G39_RS09800
uniprot id: A0A2K4BYK2
names: Similarity
messages: Belongs to the UDPGP type 2 family.

29379:I6G39 RS02725
gene id: 29379:I6G39_RS02725
uniprot id: A0A2K4C1N1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

29379:I6G39 RS07115
gene id: 29379:I6G39_RS07115
uniprot id: A0A2K4C4L0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS08760
gene id: 29379:I6G39_RS08760
uniprot id: A0A2K4BZF1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

29379:I6G39 RS06885
gene id: 29379:I6G39_RS06885
uniprot id: A0A2K4C4R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

29379:I6G39 RS04900
gene id: 29379:I6G39_RS04900
uniprot id: A0A2K4C401
names: Function
names: Similarity
names: Subunit
messages: Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. The second half-reaction is the reverse of the first, transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D-amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate, which are essential bacterial cell wall components.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

29379:I6G39 RS06605
gene id: 29379:I6G39_RS06605
uniprot id: A0A2K4C1R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

29379:I6G39 RS05670
gene id: 29379:I6G39_RS05670
uniprot id: A0A2K4BUW5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

29379:I6G39 RS02555
gene id: 29379:I6G39_RS02555
uniprot id: A0A2K4C0D3
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS04970
gene id: 29379:I6G39_RS04970
uniprot id: A0A2K4C449
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

29379:I6G39 RS03095
gene id: 29379:I6G39_RS03095
uniprot id: A0A2K4C062
names: Similarity
messages: Belongs to the IucA/IucC family.

29379:I6G39 RS09585
gene id: 29379:I6G39_RS09585
uniprot id: A0A2K4C2U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS08020
gene id: 29379:I6G39_RS08020
uniprot id: A0A2K4C178
names: Cofactor
names: Subunit
messages: Binds 1 Mg(2+) ion per trimer.
messages: Homotrimer.

29379:I6G39 RS07690
gene id: 29379:I6G39_RS07690
uniprot id: A0A2K4BU41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 1 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29379:I6G39 RS04060
gene id: 29379:I6G39_RS04060
uniprot id: A0A2K4BZP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

29379:I6G39 RS04020
gene id: 29379:I6G39_RS04020
uniprot id: A0A2K4BZN6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

29379:I6G39 RS08010
gene id: 29379:I6G39_RS08010
uniprot id: A0A2K4C174
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

29379:I6G39 RS10320
gene id: 29379:I6G39_RS10320
uniprot id: A0A2K4C1X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. HrtA family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (HrtA), two transmembrane proteins (HrtB) and a solute-binding protein.

29379:I6G39 RS01695
gene id: 29379:I6G39_RS01695
uniprot id: A0A2K4BYF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

29379:I6G39 RS02710
gene id: 29379:I6G39_RS02710
uniprot id: A0A2K4C0D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS01815
gene id: 29379:I6G39_RS01815
uniprot id: A0A2K4BY96
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

29379:I6G39 RS01805
gene id: 29379:I6G39_RS01805
uniprot id: A0A2K4BYC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

29379:I6G39 RS09975
gene id: 29379:I6G39_RS09975
uniprot id: A0A2K4BUG2
names: Similarity
messages: Belongs to the peptidase S1B family.

29379:I6G39 RS05445
gene id: 29379:I6G39_RS05445
uniprot id: A0A2K4BWZ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS10560
gene id: 29379:I6G39_RS10560
uniprot id: A0A2K4BXK0
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

29379:I6G39 RS03545
gene id: 29379:I6G39_RS03545
uniprot id: A0A2K4C3M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

29379:I6G39 RS05350
gene id: 29379:I6G39_RS05350
uniprot id: A0A2K4BYB9
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

29379:I6G39 RS02415
gene id: 29379:I6G39_RS02415
uniprot id: A0A2K4C0G1
names: Similarity
messages: Belongs to the MQO family.

29379:I6G39 RS00050
gene id: 29379:I6G39_RS00050
uniprot id: A0A2K4C0Q0
names: Function
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.

29379:I6G39 RS08445
gene id: 29379:I6G39_RS08445
uniprot id: A0A2K4C2S1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

29379:I6G39 RS09115
gene id: 29379:I6G39_RS09115
uniprot id: A0A2K4C4C6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

29379:I6G39 RS06685
gene id: 29379:I6G39_RS06685
uniprot id: A0A2K4C1K6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein.
messages: Monomer.

29379:I6G39 RS07560
gene id: 29379:I6G39_RS07560
uniprot id: A0A2K4BU65
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

29379:I6G39 RS08080
gene id: 29379:I6G39_RS08080
uniprot id: A0A2K4C235
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

29379:I6G39 RS02160
gene id: 29379:I6G39_RS02160
uniprot id: A0A2K4C2H9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS08825
gene id: 29379:I6G39_RS08825
uniprot id: A0A2K4BYX9
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS07510
gene id: 29379:I6G39_RS07510
uniprot id: A0A2K4C344
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

29379:I6G39 RS07470
gene id: 29379:I6G39_RS07470
uniprot id: A0A2K4C386
names: Function
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.
messages: Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine. Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate. Also has adenosine deaminase activity.

29379:I6G39 RS07315
gene id: 29379:I6G39_RS07315
uniprot id: A0A2K4C4I2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

29379:I6G39 RS02770
gene id: 29379:I6G39_RS02770
uniprot id: A0A2K4C088
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

29379:I6G39 RS03225
gene id: 29379:I6G39_RS03225
uniprot id: A0A2K4C3T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Cell membrane
messages: Probably a homodimer.

29379:I6G39 RS07480
gene id: 29379:I6G39_RS07480
uniprot id: A0A2K4C326
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

29379:I6G39 RS06365
gene id: 29379:I6G39_RS06365
uniprot id: A0A2K4C336
names: Similarity
messages: Belongs to the UPF0403 family.

29379:I6G39 RS09300
gene id: 29379:I6G39_RS09300
uniprot id: A0A2K4BVT1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

29379:I6G39 RS03040
gene id: 29379:I6G39_RS03040
uniprot id: A0A2K4C072
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

29379:I6G39 RS08875
gene id: 29379:I6G39_RS08875
uniprot id: A0A2K4BYZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
messages: Cytoplasm

29379:I6G39 RS09670
gene id: 29379:I6G39_RS09670
uniprot id: A0A2K4C1H4
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

29379:I6G39 RS07500
gene id: 29379:I6G39_RS07500
uniprot id: A0A2K4C328
names: Similarity
messages: Belongs to the transpeptidase family.

29379:I6G39 RS01155
gene id: 29379:I6G39_RS01155
uniprot id: A0A2K4BVA7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

29379:I6G39 RS02430
gene id: 29379:I6G39_RS02430
uniprot id: A0A2K4C0F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. HrtB subfamily.
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (HrtA), two transmembrane proteins (HrtB) and a solute-binding protein.

29379:I6G39 RS09345
gene id: 29379:I6G39_RS09345
uniprot id: A0A2K4C142
names: Similarity
messages: Belongs to the UPF0178 family.

29379:I6G39 RS09490
gene id: 29379:I6G39_RS09490
uniprot id: A0A2K4BYN9
names: Similarity
messages: Belongs to the EamA transporter family.

29379:I6G39 RS04625
gene id: 29379:I6G39_RS04625
uniprot id: A0A2K4BWR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

29379:I6G39 RS07615
gene id: 29379:I6G39_RS07615
uniprot id: A0A2K4BVD9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

29379:I6G39 RS07410
gene id: 29379:I6G39_RS07410
uniprot id: A0A2K4C363
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

29379:I6G39 RS07520
gene id: 29379:I6G39_RS07520
uniprot id: A0A2K4C376
names: Function
names: Similarity
messages: Belongs to the BshC family.
messages: Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.

29379:I6G39 RS10155
gene id: 29379:I6G39_RS10155
uniprot id: A0A2K4BXH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS06415
gene id: 29379:I6G39_RS06415
uniprot id: A0A2K4C346
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS02780
gene id: 29379:I6G39_RS02780
uniprot id: A0A2K4C1M6
names: Similarity
messages: Belongs to the GbsR family.

29379:I6G39 RS09570
gene id: 29379:I6G39_RS09570
uniprot id: A0A2K4C1I3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

29379:I6G39 RS06565
gene id: 29379:I6G39_RS06565
uniprot id: A0A2K4BWK3
names: Similarity
messages: Belongs to the CvfB family.

29379:I6G39 RS01180
gene id: 29379:I6G39_RS01180
uniprot id: A0A2K4BXY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29379:I6G39 RS08175
gene id: 29379:I6G39_RS08175
uniprot id: A0A2K4C3H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

29379:I6G39 RS07825
gene id: 29379:I6G39_RS07825
uniprot id: A0A2K4BU19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

29379:I6G39 RS10445
gene id: 29379:I6G39_RS10445
uniprot id: A0A2K4C1B5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

29379:I6G39 RS07965
gene id: 29379:I6G39_RS07965
uniprot id: A0A2K4C1C9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds a copper B center.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Heme A3.
messages: Membrane

29379:I6G39 RS07740
gene id: 29379:I6G39_RS07740
uniprot id: A0A2K4BU31
names: Similarity
messages: Belongs to the UPF0637 family.

29379:I6G39 RS00685
gene id: 29379:I6G39_RS00685
uniprot id: A0A2K4BVL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

29379:I6G39 RS02955
gene id: 29379:I6G39_RS02955
uniprot id: A0A2K4C083
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

29379:I6G39 RS05370
gene id: 29379:I6G39_RS05370
uniprot id: A0A2K4BX05
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

29379:I6G39 RS09605
gene id: 29379:I6G39_RS09605
uniprot id: A0A2K4C1G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS05235
gene id: 29379:I6G39_RS05235
uniprot id: A0A2K4C0X0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

29379:I6G39 RS08625
gene id: 29379:I6G39_RS08625
uniprot id: A0A2K4BUD6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

29379:I6G39 RS03835
gene id: 29379:I6G39_RS03835
uniprot id: A0A2K4C2H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

29379:I6G39 RS00080
gene id: 29379:I6G39_RS00080
uniprot id: A0A2K4C0P9
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS08570
gene id: 29379:I6G39_RS08570
uniprot id: A0A2K4C530
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
messages: Belongs to the DltC family.
messages: Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

29379:I6G39 RS02590
gene id: 29379:I6G39_RS02590
uniprot id: A0A2K4C0D2
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS01755
gene id: 29379:I6G39_RS01755
uniprot id: A0A2K4BYD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

29379:I6G39 RS01795
gene id: 29379:I6G39_RS01795
uniprot id: A0A2K4BYD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

29379:I6G39 RS05640
gene id: 29379:I6G39_RS05640
uniprot id: A0A2K4BUV1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

29379:I6G39 RS08245
gene id: 29379:I6G39_RS08245
uniprot id: A0A2K4BWJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS08780
gene id: 29379:I6G39_RS08780
uniprot id: A0A2K4BZF3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS03620
gene id: 29379:I6G39_RS03620
uniprot id: A0A2K4C3Q4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

29379:I6G39 RS07395
gene id: 29379:I6G39_RS07395
uniprot id: A0A2K4C347
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

29379:I6G39 RS01055
gene id: 29379:I6G39_RS01055
uniprot id: A0A7T3E4I8
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS09695
gene id: 29379:I6G39_RS09695
uniprot id: A0A2K4BXR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

29379:I6G39 RS02435
gene id: 29379:I6G39_RS02435
uniprot id: A0A2K4C0G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. HrtA family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (HrtA), two transmembrane proteins (HrtB) and a solute-binding protein.

29379:I6G39 RS03640
gene id: 29379:I6G39_RS03640
uniprot id: A0A2K4C3I7
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: Positive regulator of sigma-B activity. Non-phosphorylated RsbV binds to RsbW, preventing its association with sigma-B. When phosphorylated, releases RsbW, which is then free to complex with and inactivate sigma-B.

29379:I6G39 RS06185
gene id: 29379:I6G39_RS06185
uniprot id: A0A2K4BWY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

29379:I6G39 RS03705
gene id: 29379:I6G39_RS03705
uniprot id: A0A2K4C2A6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS01335
gene id: 29379:I6G39_RS01335
uniprot id: A0A2K4BW37
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS03435
gene id: 29379:I6G39_RS03435
uniprot id: A0A2K4C3Q3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS04955
gene id: 29379:I6G39_RS04955
uniprot id: A0A2K4C408
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0478 family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS07375
gene id: 29379:I6G39_RS07375
uniprot id: A0A2K4C3A5
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

29379:I6G39 RS05195
gene id: 29379:I6G39_RS05195
uniprot id: A0A2K4C0Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

29379:I6G39 RS03710
gene id: 29379:I6G39_RS03710
uniprot id: A0A2K4C3P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

29379:I6G39 RS05240
gene id: 29379:I6G39_RS05240
uniprot id: A0A2K4C0V4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

29379:I6G39 RS06720
gene id: 29379:I6G39_RS06720
uniprot id: A0A2K4C502
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carbamate kinase family.
messages: Cytoplasm

29379:I6G39 RS07685
gene id: 29379:I6G39_RS07685
uniprot id: A0A2K4BU44
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

29379:I6G39 RS06080
gene id: 29379:I6G39_RS06080
uniprot id: A0A2K4BV42
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS07495
gene id: 29379:I6G39_RS07495
uniprot id: A0A2K4C331
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS09825
gene id: 29379:I6G39_RS09825
uniprot id: A0A2K4BYJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS05695
gene id: 29379:I6G39_RS05695
uniprot id: A0A2K4BUV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

29379:I6G39 RS10005
gene id: 29379:I6G39_RS10005
uniprot id: A0A2K4BZ73
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

29379:I6G39 RS05810
gene id: 29379:I6G39_RS05810
uniprot id: A0A2K4BUY1
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS03965
gene id: 29379:I6G39_RS03965
uniprot id: A0A2K4BZN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

29379:I6G39 RS07350
gene id: 29379:I6G39_RS07350
uniprot id: A0A2K4C379
names: Caution
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

29379:I6G39 RS01655
gene id: 29379:I6G39_RS01655
uniprot id: A0A2K4BYG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

29379:I6G39 RS09520
gene id: 29379:I6G39_RS09520
uniprot id: A0A2K4BXB6
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

29379:I6G39 RS05510
gene id: 29379:I6G39_RS05510
uniprot id: A0A2K4BUT3
names: Similarity
messages: Belongs to the UPF0473 family.

29379:I6G39 RS06160
gene id: 29379:I6G39_RS06160
uniprot id: A0A2K4BWW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

29379:I6G39 RS03020
gene id: 29379:I6G39_RS03020
uniprot id: A0A2K4C058
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

29379:I6G39 RS09995
gene id: 29379:I6G39_RS09995
uniprot id: A0A2K4BZ72
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

29379:I6G39 RS06760
gene id: 29379:I6G39_RS06760
uniprot id: A0A2K4C4U8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

29379:I6G39 RS02315
gene id: 29379:I6G39_RS02315
uniprot id: A0A2K4C0I3
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS05025
gene id: 29379:I6G39_RS05025
uniprot id: A0A2K4BY85
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

29379:I6G39 RS04555
gene id: 29379:I6G39_RS04555
uniprot id: A0A2K4BWS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

29379:I6G39 RS04155
gene id: 29379:I6G39_RS04155
uniprot id: A0A2K4BZS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

29379:I6G39 RS05200
gene id: 29379:I6G39_RS05200
uniprot id: A0A2K4C0X6
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

29379:I6G39 RS08270
gene id: 29379:I6G39_RS08270
uniprot id: A0A2K4BWI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein required for efficient degradation of Spx by ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx and exposes the C-terminus of Spx for recognition and proteolysis by ClpXP.
messages: Belongs to the SpxH family.
messages: Cytoplasm
messages: Interacts with Spx.

29379:I6G39 RS00305
gene id: 29379:I6G39_RS00305
uniprot id: A0A2K4BWE6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

29379:I6G39 RS02760
gene id: 29379:I6G39_RS02760
uniprot id: A0A2K4C0B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

29379:I6G39 RS05765
gene id: 29379:I6G39_RS05765
uniprot id: A0A2K4BUX6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

29379:I6G39 RS02990
gene id: 29379:I6G39_RS02990
uniprot id: A0A2K4C081
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

29379:I6G39 RS08315
gene id: 29379:I6G39_RS08315
uniprot id: A0A2K4BXW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS03090
gene id: 29379:I6G39_RS03090
uniprot id: A0A2K4C027
names: Function
names: Similarity
messages: Belongs to the asp23 family.
messages: May play a key role in alkaline pH tolerance.

29379:I6G39 RS06890
gene id: 29379:I6G39_RS06890
uniprot id: A0A2K4C4S8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

29379:I6G39 RS05865
gene id: 29379:I6G39_RS05865
uniprot id: A0A2K4BUY7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

29379:I6G39 RS05515
gene id: 29379:I6G39_RS05515
uniprot id: A0A2K4BUS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

29379:I6G39 RS03500
gene id: 29379:I6G39_RS03500
uniprot id: A0A2K4C3S2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS03440
gene id: 29379:I6G39_RS03440
uniprot id: A0A2K4C3N9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

29379:I6G39 RS09525
gene id: 29379:I6G39_RS09525
uniprot id: A0A2K4BXD7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29379:I6G39 RS01775
gene id: 29379:I6G39_RS01775
uniprot id: A0A2K4BYD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

29379:I6G39 RS04205
gene id: 29379:I6G39_RS04205
uniprot id: A0A2K4BZT2
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Homodimer; disulfide-linked, upon oxidation. 5 homodimers assemble to form a ring-like decamer.

29379:I6G39 RS00345
gene id: 29379:I6G39_RS00345
uniprot id: A0A2K4BWC5
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS08505
gene id: 29379:I6G39_RS08505
uniprot id: A0A2K4BX39
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

29379:I6G39 RS06785
gene id: 29379:I6G39_RS06785
uniprot id: A0A2K4C4U7
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

29379:I6G39 RS01925
gene id: 29379:I6G39_RS01925
uniprot id: A0A2K4C2N1
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

29379:I6G39 RS06825
gene id: 29379:I6G39_RS06825
uniprot id: A0A2K4C4R5
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

29379:I6G39 RS03945
gene id: 29379:I6G39_RS03945
uniprot id: A0A2K4BZN0
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS03475
gene id: 29379:I6G39_RS03475
uniprot id: A0A2K4C3N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

29379:I6G39 RS09965
gene id: 29379:I6G39_RS09965
uniprot id: A0A2K4BYI0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. RocA subfamily.

29379:I6G39 RS05400
gene id: 29379:I6G39_RS05400
uniprot id: A0A2K4BYB4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

29379:I6G39 RS05115
gene id: 29379:I6G39_RS05115
uniprot id: A0A2K4BVS7
names: Similarity
messages: Belongs to the UPF0173 family.

29379:I6G39 RS08455
gene id: 29379:I6G39_RS08455
uniprot id: A0A2K4C2Y0
names: Function
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

29379:I6G39 RS02875
gene id: 29379:I6G39_RS02875
uniprot id: A0A2K4C097
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS03515
gene id: 29379:I6G39_RS03515
uniprot id: A0A2K4C3R1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS03420
gene id: 29379:I6G39_RS03420
uniprot id: A0A2K4C3N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

29379:I6G39 RS07930
gene id: 29379:I6G39_RS07930
uniprot id: A0A2K4BTY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

29379:I6G39 RS05405
gene id: 29379:I6G39_RS05405
uniprot id: A0A2K4BWY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

29379:I6G39 RS03035
gene id: 29379:I6G39_RS03035
uniprot id: A0A2K4C037
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

29379:I6G39 RS06790
gene id: 29379:I6G39_RS06790
uniprot id: A0A2K4C4W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

29379:I6G39 RS09455
gene id: 29379:I6G39_RS09455
uniprot id: A0A2K4BXF3
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

29379:I6G39 RS04075
gene id: 29379:I6G39_RS04075
uniprot id: A0A2K4C140
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

29379:I6G39 RS09065
gene id: 29379:I6G39_RS09065
uniprot id: A0A2K4C4D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

29379:I6G39 RS02910
gene id: 29379:I6G39_RS02910
uniprot id: A0A2K4C080
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

29379:I6G39 RS05055
gene id: 29379:I6G39_RS05055
uniprot id: A0A2K4BY92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

29379:I6G39 RS09265
gene id: 29379:I6G39_RS09265
uniprot id: A0A2K4C4E9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

29379:I6G39 RS00585
gene id: 29379:I6G39_RS00585
uniprot id: A0A2K4BTU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

29379:I6G39 RS08185
gene id: 29379:I6G39_RS08185
uniprot id: A0A2K4C294
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS04210
gene id: 29379:I6G39_RS04210
uniprot id: A0A2K4BZS9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

29379:I6G39 RS08095
gene id: 29379:I6G39_RS08095
uniprot id: A0A2K4C256
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

29379:I6G39 RS04500
gene id: 29379:I6G39_RS04500
uniprot id: A0A2K4BY12
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS05360
gene id: 29379:I6G39_RS05360
uniprot id: A0A2K4BX13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

29379:I6G39 RS06635
gene id: 29379:I6G39_RS06635
uniprot id: A0A2K4C1M1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

29379:I6G39 RS00245
gene id: 29379:I6G39_RS00245
uniprot id: A0A2K4BWB5
names: Similarity
messages: Belongs to the aldolase LacD family.

29379:I6G39 RS08400
gene id: 29379:I6G39_RS08400
uniprot id: A0A2K4C2T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

29379:I6G39 RS06775
gene id: 29379:I6G39_RS06775
uniprot id: A0A2K4C4Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

29379:I6G39 RS09900
gene id: 29379:I6G39_RS09900
uniprot id: A0A2K4BYL8
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS08385
gene id: 29379:I6G39_RS08385
uniprot id: A0A2K4C2S8
names: Similarity
messages: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family.

29379:I6G39 RS10260
gene id: 29379:I6G39_RS10260
uniprot id: A0A2K4BYC9
names: Subcellular Location Annotation
messages: cell wall

29379:I6G39 RS01745
gene id: 29379:I6G39_RS01745
uniprot id: A0A2K4BYE9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

29379:I6G39 RS07035
gene id: 29379:I6G39_RS07035
uniprot id: A0A2K4C4N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

29379:I6G39 RS05430
gene id: 29379:I6G39_RS05430
uniprot id: A0A2K4BWZ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

29379:I6G39 RS07840
gene id: 29379:I6G39_RS07840
uniprot id: A0A2K4BU22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

29379:I6G39 RS00655
gene id: 29379:I6G39_RS00655
uniprot id: A0A2K4C1R6
names: Similarity
messages: Belongs to the ParB family.

29379:I6G39 RS02185
gene id: 29379:I6G39_RS02185
uniprot id: A0A2K4C2G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS07985
gene id: 29379:I6G39_RS07985
uniprot id: A0A2K4C1C1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

29379:I6G39 RS00660
gene id: 29379:I6G39_RS00660
uniprot id: A0A2K4C1W6
names: Subcellular Location Annotation
messages: cell wall

29379:I6G39 RS06390
gene id: 29379:I6G39_RS06390
uniprot id: A0A2K4C2Z4
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS06405
gene id: 29379:I6G39_RS06405
uniprot id: A0A2K4C2Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41A family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS01175
gene id: 29379:I6G39_RS01175
uniprot id: A0A2K4BXY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
messages: Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
messages: Cytoplasm

29379:I6G39 RS06040
gene id: 29379:I6G39_RS06040
uniprot id: A0A2K4BV13
names: Similarity
messages: Belongs to the Nudix hydrolase family.

29379:I6G39 RS02840
gene id: 29379:I6G39_RS02840
uniprot id: A0A2K4C084
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

29379:I6G39 RS06700
gene id: 29379:I6G39_RS06700
uniprot id: A0A2K4C4Z0
names: Similarity
names: Subunit
messages: Belongs to the SMC family. SbcC subfamily.
messages: Heterodimer of SbcC and SbcD.

29379:I6G39 RS01465
gene id: 29379:I6G39_RS01465
uniprot id: A0A2K4BYW2
names: Similarity
messages: Belongs to the RutC family.

29379:I6G39 RS02920
gene id: 29379:I6G39_RS02920
uniprot id: A0A2K4C078
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

29379:I6G39 RS09075
gene id: 29379:I6G39_RS09075
uniprot id: A0A2K4C4H2
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

29379:I6G39 RS05750
gene id: 29379:I6G39_RS05750
uniprot id: A0A2K4BUW6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

29379:I6G39 RS00150
gene id: 29379:I6G39_RS00150
uniprot id: A0A2K4C0R3
names: Similarity
messages: Belongs to the acyltransferase 3 family.

29379:I6G39 RS05925
gene id: 29379:I6G39_RS05925
uniprot id: A0A2K4BV18
names: Function
names: Similarity
messages: Belongs to the asp23 family.
messages: May play a key role in alkaline pH tolerance.

29379:I6G39 RS06065
gene id: 29379:I6G39_RS06065
uniprot id: A0A2K4BWC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

29379:I6G39 RS07095
gene id: 29379:I6G39_RS07095
uniprot id: A0A2K4C4M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

29379:I6G39 RS07090
gene id: 29379:I6G39_RS07090
uniprot id: A0A2K4C4T9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

29379:I6G39 RS01390
gene id: 29379:I6G39_RS01390
uniprot id: A0A2K4BYS7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

29379:I6G39 RS10440
gene id: 29379:I6G39_RS10440
uniprot id: A0A2K4C1F6
names: Similarity
messages: Belongs to the acyltransferase 3 family.

29379:I6G39 RS00515
gene id: 29379:I6G39_RS00515
uniprot id: A0A2K4BTV8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS07255
gene id: 29379:I6G39_RS07255
uniprot id: A0A2K4C393
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

29379:I6G39 RS07205
gene id: 29379:I6G39_RS07205
uniprot id: A0A2K4BZ64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

29379:I6G39 RS08885
gene id: 29379:I6G39_RS08885
uniprot id: A0A2K4BZ00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

29379:I6G39 RS08000
gene id: 29379:I6G39_RS08000
uniprot id: A0A2K4C1A1
names: Similarity
messages: Belongs to the aldolase LacD family.

29379:I6G39 RS05070
gene id: 29379:I6G39_RS05070
uniprot id: A0A2K4BYB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS06745
gene id: 29379:I6G39_RS06745
uniprot id: A0A2K4C4S7
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS06385
gene id: 29379:I6G39_RS06385
uniprot id: A0A2K4C2Y9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

29379:I6G39 RS02450
gene id: 29379:I6G39_RS02450
uniprot id: A0A2K4C0H6
names: Subcellular Location Annotation
messages: Cell membrane

29379:I6G39 RS10620
gene id: 29379:I6G39_RS10620
uniprot id: A0A2K4BXH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family. SecY2 subfamily.
messages: Cell membrane
messages: Component of the accessory SecA2/SecY2 protein translocase complex required to export cell wall proteins. May form heterotrimers with SecE and SecG subunits.
messages: Part of the accessory SecA2/SecY2 system specifically required for export of possible cell wall proteins. The central subunit of a protein translocation channel.

29379:I6G39 RS01100
gene id: 29379:I6G39_RS01100
uniprot id: A0A2K4BWM6
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

29379:I6G39 RS09135
gene id: 29379:I6G39_RS09135
uniprot id: A0A2K4C4K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS10065
gene id: 29379:I6G39_RS10065
uniprot id: A0A2K4BUP6
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

29379:I6G39 RS08045
gene id: 29379:I6G39_RS08045
uniprot id: A0A2K4C198
names: Similarity
messages: Belongs to the UPF0039 (ElaA) family.

29379:I6G39 RS06615
gene id: 29379:I6G39_RS06615
uniprot id: A0A2K4C1N4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

29379:I6G39 RS09940
gene id: 29379:I6G39_RS09940
uniprot id: A0A2K4BYG4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

29379:I6G39 RS04620
gene id: 29379:I6G39_RS04620
uniprot id: A0A2K4BWS4
names: Similarity
messages: Belongs to the TRAP family.

29379:I6G39 RS07885
gene id: 29379:I6G39_RS07885
uniprot id: A0A2K4BU08
names: Similarity
messages: Belongs to the GARS family.

29379:I6G39 RS09215
gene id: 29379:I6G39_RS09215
uniprot id: A0A2K4C4F7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

29379:I6G39 RS05940
gene id: 29379:I6G39_RS05940
uniprot id: A0A2K4BV02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

29379:I6G39 RS07910
gene id: 29379:I6G39_RS07910
uniprot id: A0A2K4BU30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

29379:I6G39 RS05980
gene id: 29379:I6G39_RS05980
uniprot id: A0A2K4BV28
names: Similarity
messages: Belongs to the UPF0403 family.

29379:I6G39 RS10010
gene id: 29379:I6G39_RS10010
uniprot id: A0A2K4BZ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

29379:I6G39 RS04215
gene id: 29379:I6G39_RS04215
uniprot id: A0A2K4BZU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fur family.
messages: Cytoplasm

29379:I6G39 RS05660
gene id: 29379:I6G39_RS05660
uniprot id: A0A2K4BUU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

29379:I6G39 RS01680
gene id: 29379:I6G39_RS01680
uniprot id: A0A2K4BYE5
names: Similarity
messages: Belongs to the ClpA/ClpB family. ClpC subfamily.

29379:I6G39 RS09955
gene id: 29379:I6G39_RS09955
uniprot id: A0A2K4BYE8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

29379:I6G39 RS05045
gene id: 29379:I6G39_RS05045
uniprot id: A0A2K4BYA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

29379:I6G39 RS06490
gene id: 29379:I6G39_RS06490
uniprot id: A0A2K4BWV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

29379:I6G39 RS04995
gene id: 29379:I6G39_RS04995
uniprot id: A0A2K4BUL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

29379:I6G39 RS03590
gene id: 29379:I6G39_RS03590
uniprot id: A0A2K4C3J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

29379:I6G39 RS06070
gene id: 29379:I6G39_RS06070
uniprot id: A0A2K4BV22
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

29379:I6G39 RS07415
gene id: 29379:I6G39_RS07415
uniprot id: A0A2K4C396
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

29379:I6G39 RS06765
gene id: 29379:I6G39_RS06765
uniprot id: A0A2K4C4S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

29379:I6G39 RS07245
gene id: 29379:I6G39_RS07245
uniprot id: A0A2K4C3E2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

29379:I6G39 RS07765
gene id: 29379:I6G39_RS07765
uniprot id: A0A2K4BVB0
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS06380
gene id: 29379:I6G39_RS06380
uniprot id: A0A2K4C359
names: Function
messages: May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.

29379:I6G39 RS03320
gene id: 29379:I6G39_RS03320
uniprot id: A0A2K4C3W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

29379:I6G39 RS10245
gene id: 29379:I6G39_RS10245
uniprot id: A0A2K4BX41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

29379:I6G39 RS10275
gene id: 29379:I6G39_RS10275
uniprot id: A0A2K4C237
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

29379:I6G39 RS07360
gene id: 29379:I6G39_RS07360
uniprot id: A0A2K4C3B0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS08960
gene id: 29379:I6G39_RS08960
uniprot id: A0A2K4C4G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

29379:I6G39 RS09130
gene id: 29379:I6G39_RS09130
uniprot id: A0A2K4C5N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

29379:I6G39 RS01840
gene id: 29379:I6G39_RS01840
uniprot id: A0A2K4BZS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS08075
gene id: 29379:I6G39_RS08075
uniprot id: A0A2K4C257
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS02005
gene id: 29379:I6G39_RS02005
uniprot id: A0A2K4C2R5
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

29379:I6G39 RS03170
gene id: 29379:I6G39_RS03170
uniprot id: A0A2K4BY09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

29379:I6G39 RS06705
gene id: 29379:I6G39_RS06705
uniprot id: A0A2K4C4V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

29379:I6G39 RS03840
gene id: 29379:I6G39_RS03840
uniprot id: A0A2K4C2D5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

29379:I6G39 RS10570
gene id: 29379:I6G39_RS10570
uniprot id: A0A2K4BXI6
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

29379:I6G39 RS06880
gene id: 29379:I6G39_RS06880
uniprot id: A0A2K4C4Y2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

29379:I6G39 RS05260
gene id: 29379:I6G39_RS05260
uniprot id: A0A2K4C0Z7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

29379:I6G39 RS06665
gene id: 29379:I6G39_RS06665
uniprot id: A0A2K4C1L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

29379:I6G39 RS00380
gene id: 29379:I6G39_RS00380
uniprot id: A0A2X5CR22
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS01425
gene id: 29379:I6G39_RS01425
uniprot id: A0A2K4BYT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

29379:I6G39 RS06975
gene id: 29379:I6G39_RS06975
uniprot id: A0A2K4C4P0
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

29379:I6G39 RS08915
gene id: 29379:I6G39_RS08915
uniprot id: A0A2K4BYZ8
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

29379:I6G39 RS09160
gene id: 29379:I6G39_RS09160
uniprot id: A0A2K4C498
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS05155
gene id: 29379:I6G39_RS05155
uniprot id: A0A2K4C120
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

29379:I6G39 RS06535
gene id: 29379:I6G39_RS06535
uniprot id: A0A2K4BWV2
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

29379:I6G39 RS02150
gene id: 29379:I6G39_RS02150
uniprot id: A0A2K4C2M7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

29379:I6G39 RS01970
gene id: 29379:I6G39_RS01970
uniprot id: A0A2K4C2T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

29379:I6G39 RS10060
gene id: 29379:I6G39_RS10060
uniprot id: A0A2K4BUL8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29379:I6G39 RS09140
gene id: 29379:I6G39_RS09140
uniprot id: A0A2K4C492
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS10215
gene id: 29379:I6G39_RS10215
uniprot id: A0A2K4BX36
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

29379:I6G39 RS05965
gene id: 29379:I6G39_RS05965
uniprot id: A0A2K4BV03
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

29379:I6G39 RS04880
gene id: 29379:I6G39_RS04880
uniprot id: A0A2K4C420
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS01800
gene id: 29379:I6G39_RS01800
uniprot id: A0A2K4BYA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

29379:I6G39 RS10200
gene id: 29379:I6G39_RS10200
uniprot id: A0A2K4BX33
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

29379:I6G39 RS06905
gene id: 29379:I6G39_RS06905
uniprot id: A0A2K4C4P8
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

29379:I6G39 RS08215
gene id: 29379:I6G39_RS08215
uniprot id: A0A2K4BWJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

29379:I6G39 RS04100
gene id: 29379:I6G39_RS04100
uniprot id: A0A2K4BZR1
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

29379:I6G39 RS08225
gene id: 29379:I6G39_RS08225
uniprot id: A0A2K4BWH1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

29379:I6G39 RS07505
gene id: 29379:I6G39_RS07505
uniprot id: A0A2K4C392
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

29379:I6G39 RS10160
gene id: 29379:I6G39_RS10160
uniprot id: A0A2K4BXH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS02000
gene id: 29379:I6G39_RS02000
uniprot id: A0A2K4C2K6
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the octanoyltransferase LipL family.
messages: Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.
messages: The reaction proceeds via a thioester-linked acyl-enzyme intermediate.

29379:I6G39 RS07455
gene id: 29379:I6G39_RS07455
uniprot id: A0A2K4C357
names: Similarity
messages: Belongs to the YggT family.

29379:I6G39 RS10075
gene id: 29379:I6G39_RS10075
uniprot id: A0A2K4BUN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

29379:I6G39 RS06875
gene id: 29379:I6G39_RS06875
uniprot id: A0A2K4C4Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

29379:I6G39 RS02030
gene id: 29379:I6G39_RS02030
uniprot id: A0A2K4C2L3
names: Similarity
names: Subunit
messages: Belongs to the azoreductase type 2 family.
messages: Homotetramer.

29379:I6G39 RS05800
gene id: 29379:I6G39_RS05800
uniprot id: A0A2K4BV63
names: Similarity
messages: Belongs to the transpeptidase family.

29379:I6G39 RS07940
gene id: 29379:I6G39_RS07940
uniprot id: A0A2K4BU07
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS04010
gene id: 29379:I6G39_RS04010
uniprot id: A0A2K4BZN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS02915
gene id: 29379:I6G39_RS02915
uniprot id: A0A2K4C079
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

29379:I6G39 RS00750
gene id: 29379:I6G39_RS00750
uniprot id: A0A2K4BVM7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

29379:I6G39 RS04795
gene id: 29379:I6G39_RS04795
uniprot id: A0A2K4C3Y1
names: Similarity
messages: In the N-terminal section; belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

29379:I6G39 RS07710
gene id: 29379:I6G39_RS07710
uniprot id: A0A2K4BU38
names: Similarity
messages: Belongs to the UPF0358 family.

29379:I6G39 RS01705
gene id: 29379:I6G39_RS01705
uniprot id: A0A2K4BYF0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

29379:I6G39 RS09925
gene id: 29379:I6G39_RS09925
uniprot id: A0A2K4BYM2
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS02705
gene id: 29379:I6G39_RS02705
uniprot id: A0A2K4C0C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS01900
gene id: 29379:I6G39_RS01900
uniprot id: A0A2K4BZX9
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

29379:I6G39 RS09275
gene id: 29379:I6G39_RS09275
uniprot id: A0A2K4C4A2
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

29379:I6G39 RS10190
gene id: 29379:I6G39_RS10190
uniprot id: A0A2K4BXG9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

29379:I6G39 RS05645
gene id: 29379:I6G39_RS05645
uniprot id: A0A2K4BUU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

29379:I6G39 RS10305
gene id: 29379:I6G39_RS10305
uniprot id: A0A2K4C1X8
names: Similarity
messages: Belongs to the peptidase C59 family.

29379:I6G39 RS05820
gene id: 29379:I6G39_RS05820
uniprot id: A0A2K4BUY6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

29379:I6G39 RS10120
gene id: 29379:I6G39_RS10120
uniprot id: A0A2K4BXF7
names: Subunit
messages: Homodimer.

29379:I6G39 RS10125
gene id: 29379:I6G39_RS10125
uniprot id: A0A2K4BXH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

29379:I6G39 RS04740
gene id: 29379:I6G39_RS04740
uniprot id: A0A2K4C428
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS05595
gene id: 29379:I6G39_RS05595
uniprot id: A0A2K4BUU1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

29379:I6G39 RS05605
gene id: 29379:I6G39_RS05605
uniprot id: A0A2K4BUU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

29379:I6G39 RS06210
gene id: 29379:I6G39_RS06210
uniprot id: A0A2K4C312
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS03100
gene id: 29379:I6G39_RS03100
uniprot id: A0A2K4BY28
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS07140
gene id: 29379:I6G39_RS07140
uniprot id: A0A2K4C4T1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

29379:I6G39 RS01875
gene id: 29379:I6G39_RS01875
uniprot id: A0A2K4BZW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

29379:I6G39 RS03505
gene id: 29379:I6G39_RS03505
uniprot id: A0A2K4C4Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

29379:I6G39 RS07810
gene id: 29379:I6G39_RS07810
uniprot id: A0A2K4BU17
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

29379:I6G39 RS06940
gene id: 29379:I6G39_RS06940
uniprot id: A0A2K4C4R7
names: Similarity
messages: Belongs to the UPF0045 family.

29379:I6G39 RS10590
gene id: 29379:I6G39_RS10590
uniprot id: A0A2K4BXI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GtfB family.
messages: Cell membrane
messages: Forms a heterotetramer with 2 subunits each of GtfA and GtfB. Part of the accessory SecA2/SecY2 protein translocation apparatus.
messages: Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. A stabilizing protein that is part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. The GtfA-GtfB complex adds GlcNAc from UDP-GlcNAc to the substrate protein, attaching the first sugar residue. Stabilizes the glycosylation activity of GtfA. Has no N-acetylglucosaminyl transferase activity on its own.

29379:I6G39 RS08985
gene id: 29379:I6G39_RS08985
uniprot id: A0A2K4C4H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

29379:I6G39 RS07120
gene id: 29379:I6G39_RS07120
uniprot id: A0A2K4C4Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

29379:I6G39 RS03630
gene id: 29379:I6G39_RS03630
uniprot id: A0A2K4C3I5
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

29379:I6G39 RS08940
gene id: 29379:I6G39_RS08940
uniprot id: A0A2K4BZ06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

29379:I6G39 RS10055
gene id: 29379:I6G39_RS10055
uniprot id: A0A2K4BUN4
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS06625
gene id: 29379:I6G39_RS06625
uniprot id: A0A2K4C1N7
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

29379:I6G39 RS00300
gene id: 29379:I6G39_RS00300
uniprot id: A0A2K4BWB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS06480
gene id: 29379:I6G39_RS06480
uniprot id: A0A2K4BYE6
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

29379:I6G39 RS02360
gene id: 29379:I6G39_RS02360
uniprot id: A0A2K4C0L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

29379:I6G39 RS03645
gene id: 29379:I6G39_RS03645
uniprot id: A0A2K4C3J9
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).

29379:I6G39 RS04055
gene id: 29379:I6G39_RS04055
uniprot id: A0A2K4BZQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

29379:I6G39 RS07055
gene id: 29379:I6G39_RS07055
uniprot id: A0A2K4C4T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

29379:I6G39 RS07390
gene id: 29379:I6G39_RS07390
uniprot id: A0A2K4C355
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

29379:I6G39 RS07265
gene id: 29379:I6G39_RS07265
uniprot id: A0A2K4C4J4
names: Similarity
messages: Belongs to the fabD family.

29379:I6G39 RS03335
gene id: 29379:I6G39_RS03335
uniprot id: A0A2K4C3R0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

29379:I6G39 RS07230
gene id: 29379:I6G39_RS07230
uniprot id: A0A2K4C380
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

29379:I6G39 RS05995
gene id: 29379:I6G39_RS05995
uniprot id: A0A2X5ADC6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

29379:I6G39 RS03650
gene id: 29379:I6G39_RS03650
uniprot id: A0A2K4C3K3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

29379:I6G39 RS01145
gene id: 29379:I6G39_RS01145
uniprot id: A0A2K4BVB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

29379:I6G39 RS05730
gene id: 29379:I6G39_RS05730
uniprot id: A0A2K4BUX4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

29379:I6G39 RS09255
gene id: 29379:I6G39_RS09255
uniprot id: A0A2K4C493
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

29379:I6G39 RS02260
gene id: 29379:I6G39_RS02260
uniprot id: A0A2K4C0I7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

29379:I6G39 RS05920
gene id: 29379:I6G39_RS05920
uniprot id: A0A2K4BUZ4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

29379:I6G39 RS01915
gene id: 29379:I6G39_RS01915
uniprot id: A0A2K4C2T2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS04120
gene id: 29379:I6G39_RS04120
uniprot id: A0A2K4BZQ6
names: Similarity
messages: Belongs to the UPF0435 family.

29379:I6G39 RS09120
gene id: 29379:I6G39_RS09120
uniprot id: A0A2K4C4C7
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

29379:I6G39 RS09040
gene id: 29379:I6G39_RS09040
uniprot id: A0A2K4C4G2
names: Function
messages: May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.

29379:I6G39 RS07570
gene id: 29379:I6G39_RS07570
uniprot id: A0A2K4BU72
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

29379:I6G39 RS09070
gene id: 29379:I6G39_RS09070
uniprot id: A0A2K4C4D7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

29379:I6G39 RS10285
gene id: 29379:I6G39_RS10285
uniprot id: A0A2K4C1Y0
names: Similarity
messages: Belongs to the MQO family.

29379:I6G39 RS06440
gene id: 29379:I6G39_RS06440
uniprot id: A0A2K4C2Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Forms a 24-polypeptide structural core with octahedral symmetry. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

29379:I6G39 RS10180
gene id: 29379:I6G39_RS10180
uniprot id: A0A2K4BXE5
names: Similarity
names: Subunit
messages: Belongs to the azoreductase type 2 family.
messages: Homotetramer.

29379:I6G39 RS00785
gene id: 29379:I6G39_RS00785
uniprot id: A0A2K4BVP4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

29379:I6G39 RS05985
gene id: 29379:I6G39_RS05985
uniprot id: A0A2K4BV04
names: Similarity
messages: Belongs to the UPF0421 family.

29379:I6G39 RS08900
gene id: 29379:I6G39_RS08900
uniprot id: A0A2K4C0D6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

29379:I6G39 RS08390
gene id: 29379:I6G39_RS08390
uniprot id: A0A2K4C2R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0344 family.
messages: Cell membrane

29379:I6G39 RS08705
gene id: 29379:I6G39_RS08705
uniprot id: A0A2K4BZF2
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

29379:I6G39 RS07110
gene id: 29379:I6G39_RS07110
uniprot id: A0A2K4C5Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

29379:I6G39 RS08350
gene id: 29379:I6G39_RS08350
uniprot id: A0A2K4C2U6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

29379:I6G39 RS02390
gene id: 29379:I6G39_RS02390
uniprot id: A0A2K4C0I4
names: Similarity
messages: Belongs to the UPF0039 (ElaA) family.

29379:I6G39 RS00725
gene id: 29379:I6G39_RS00725
uniprot id: A0A2X5B1R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. HrtB subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (HrtA), two transmembrane proteins (HrtB) and a solute-binding protein.

29379:I6G39 RS01850
gene id: 29379:I6G39_RS01850
uniprot id: A0A2K4BZV3
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

29379:I6G39 RS00575
gene id: 29379:I6G39_RS00575
uniprot id: A0A2K4BTW4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS08810
gene id: 29379:I6G39_RS08810
uniprot id: A0A2X5A133
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

29379:I6G39 RS09540
gene id: 29379:I6G39_RS09540
uniprot id: A0A2K4BYN0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

29379:I6G39 RS08500
gene id: 29379:I6G39_RS08500
uniprot id: A0A2T4MCL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS08930
gene id: 29379:I6G39_RS08930
uniprot id: A0A2K4BYZ9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

29379:I6G39 RS09050
gene id: 29379:I6G39_RS09050
uniprot id: A0A2K4C4D5
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS02195
gene id: 29379:I6G39_RS02195
uniprot id: A0A2K4C2N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS05735
gene id: 29379:I6G39_RS05735
uniprot id: A0A2K4BUW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

29379:I6G39 RS06980
gene id: 29379:I6G39_RS06980
uniprot id: A0A2K4C4W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

29379:I6G39 RS00090
gene id: 29379:I6G39_RS00090
uniprot id: A0A2K4C0T2
names: Function
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.

29379:I6G39 RS03260
gene id: 29379:I6G39_RS03260
uniprot id: A0A2K4C3R4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

29379:I6G39 RS07150
gene id: 29379:I6G39_RS07150
uniprot id: A0A2K4C4M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

29379:I6G39 RS02145
gene id: 29379:I6G39_RS02145
uniprot id: A0A2K4C2H4
names: Similarity
messages: Belongs to the GppA/Ppx family.

29379:I6G39 RS00765
gene id: 29379:I6G39_RS00765
uniprot id: A0A2K4BVN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

29379:I6G39 RS06815
gene id: 29379:I6G39_RS06815
uniprot id: A0A2K4C4U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

29379:I6G39 RS04760
gene id: 29379:I6G39_RS04760
uniprot id: A0A2K4C407
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

29379:I6G39 RS00640
gene id: 29379:I6G39_RS00640
uniprot id: A0A2K4C340
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS03390
gene id: 29379:I6G39_RS03390
uniprot id: A0A2K4C3P8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

29379:I6G39 RS10265
gene id: 29379:I6G39_RS10265
uniprot id: A0A2K4BX04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IsdC family.
messages: cell wall

29379:I6G39 RS05295
gene id: 29379:I6G39_RS05295
uniprot id: A0A2K4C0Z5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

29379:I6G39 RS02305
gene id: 29379:I6G39_RS02305
uniprot id: A0A2K4C0H5
names: Similarity
messages: Belongs to the UPF0312 family.

29379:I6G39 RS07075
gene id: 29379:I6G39_RS07075
uniprot id: A0A2K4C4N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

29379:I6G39 RS08775
gene id: 29379:I6G39_RS08775
uniprot id: A0A2K4BZE7
names: Similarity
messages: Belongs to the nitroreductase family.

29379:I6G39 RS07790
gene id: 29379:I6G39_RS07790
uniprot id: A0A2K4BU29
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

29379:I6G39 RS10165
gene id: 29379:I6G39_RS10165
uniprot id: A0A2K4BXF6
names: Similarity
messages: Belongs to the CapA family.

29379:I6G39 RS08440
gene id: 29379:I6G39_RS08440
uniprot id: A0A2K4C2Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
messages: Catalyzes the interconversion of ornithine to glutamate semialdehyde.
messages: Cytoplasm

29379:I6G39 RS00580
gene id: 29379:I6G39_RS00580
uniprot id: A0A2K4BTU1
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

29379:I6G39 RS04860
gene id: 29379:I6G39_RS04860
uniprot id: A0A2K4C427
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS08800
gene id: 29379:I6G39_RS08800
uniprot id: A0A2X5A999
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

29379:I6G39 RS05455
gene id: 29379:I6G39_RS05455
uniprot id: A0A2X5D771
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

29379:I6G39 RS03490
gene id: 29379:I6G39_RS03490
uniprot id: A0A2K4C3M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

29379:I6G39 RS04130
gene id: 29379:I6G39_RS04130
uniprot id: A0A2K4BZT5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

29379:I6G39 RS04045
gene id: 29379:I6G39_RS04045
uniprot id: A0A2K4BZP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

29379:I6G39 RS06050
gene id: 29379:I6G39_RS06050
uniprot id: A0A2K4BV46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

29379:I6G39 RS07600
gene id: 29379:I6G39_RS07600
uniprot id: A0A2K4BU85
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS00705
gene id: 29379:I6G39_RS00705
uniprot id: A0A2K4BVL8
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

29379:I6G39 RS06860
gene id: 29379:I6G39_RS06860
uniprot id: A0A2K4C4V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism. It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Feedback-inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA. During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation. Under conditions of nitrogen excess, feedback-inhibited GlnA forms a stable complex with TnrA, which inhibits its DNA-binding activity. In contrast, feedback-inhibited GlnA acts as a chaperone to stabilize the DNA-binding activity of GlnR, which represses the transcription of nitrogen assimilation genes.
messages: Oligomer of 12 subunits arranged in the form of two hexagons. In its feedback-inhibited form, interacts with TnrA in order to block its DNA-binding activity.

29379:I6G39 RS08715
gene id: 29379:I6G39_RS08715
uniprot id: A0A2K4C0V5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

29379:I6G39 RS05910
gene id: 29379:I6G39_RS05910
uniprot id: A0A2K4BW90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

29379:I6G39 RS05930
gene id: 29379:I6G39_RS05930
uniprot id: A0A2K4BV08
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

29379:I6G39 RS00670
gene id: 29379:I6G39_RS00670
uniprot id: A0A2K4BVN3
names: Similarity
messages: Belongs to the SMP-30/CGR1 family.

29379:I6G39 RS06630
gene id: 29379:I6G39_RS06630
uniprot id: A0A2K4C1N3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

29379:I6G39 RS03445
gene id: 29379:I6G39_RS03445
uniprot id: A0A2K4C3T4
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

29379:I6G39 RS00855
gene id: 29379:I6G39_RS00855
uniprot id: A0A2K4BVH1
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS09915
gene id: 29379:I6G39_RS09915
uniprot id: A0A2K4BZX7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

29379:I6G39 RS07760
gene id: 29379:I6G39_RS07760
uniprot id: A0A2K4BU26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS02180
gene id: 29379:I6G39_RS02180
uniprot id: A0A2K4C2H8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

29379:I6G39 RS07080
gene id: 29379:I6G39_RS07080
uniprot id: A0A2K4C4N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

29379:I6G39 RS07370
gene id: 29379:I6G39_RS07370
uniprot id: A0A2K4C353
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

29379:I6G39 RS08645
gene id: 29379:I6G39_RS08645
uniprot id: A0A2K4BVJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

29379:I6G39 RS05585
gene id: 29379:I6G39_RS05585
uniprot id: A0A2K4BW24
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS09950
gene id: 29379:I6G39_RS09950
uniprot id: A0A2K4BYH9
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS05180
gene id: 29379:I6G39_RS05180
uniprot id: A0A2K4C0Y0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS10220
gene id: 29379:I6G39_RS10220
uniprot id: A0A2K4BX23
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

29379:I6G39 RS08525
gene id: 29379:I6G39_RS08525
uniprot id: A0A2K4C4X9
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS05665
gene id: 29379:I6G39_RS05665
uniprot id: A0A2K4BUV4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

29379:I6G39 RS03290
gene id: 29379:I6G39_RS03290
uniprot id: A0A2K4C543
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

29379:I6G39 RS00545
gene id: 29379:I6G39_RS00545
uniprot id: A0A2K4BTT7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

29379:I6G39 RS03370
gene id: 29379:I6G39_RS03370
uniprot id: A0A2K4C3P6
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

29379:I6G39 RS10040
gene id: 29379:I6G39_RS10040
uniprot id: A0A2K4BZ61
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS04635
gene id: 29379:I6G39_RS04635
uniprot id: A0A2K4BWT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

29379:I6G39 RS04035
gene id: 29379:I6G39_RS04035
uniprot id: A0A2K4BZN1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

29379:I6G39 RS02285
gene id: 29379:I6G39_RS02285
uniprot id: A0A2K4C0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS00535
gene id: 29379:I6G39_RS00535
uniprot id: A0A2K4BTU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

29379:I6G39 RS09380
gene id: 29379:I6G39_RS09380
uniprot id: A0A2K4C196
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29379:I6G39 RS08340
gene id: 29379:I6G39_RS08340
uniprot id: A0A2K4BZ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS02735
gene id: 29379:I6G39_RS02735
uniprot id: A0A2K4C0L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

29379:I6G39 RS05535
gene id: 29379:I6G39_RS05535
uniprot id: A0A2K4BUT2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

29379:I6G39 RS09185
gene id: 29379:I6G39_RS09185
uniprot id: A0A2K4C5M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate. Is required for staphylococcal growth and cell division process.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS08345
gene id: 29379:I6G39_RS08345
uniprot id: A0A2K4BXU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS08030
gene id: 29379:I6G39_RS08030
uniprot id: A0A2K4C191
names: Similarity
messages: Belongs to the phosphohexose mutase family.

29379:I6G39 RS08605
gene id: 29379:I6G39_RS08605
uniprot id: A0A2K4BUE8
names: Similarity
messages: Belongs to the HepT RNase toxin family.

29379:I6G39 RS05065
gene id: 29379:I6G39_RS05065
uniprot id: A0A2K4BY77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

29379:I6G39 RS05775
gene id: 29379:I6G39_RS05775
uniprot id: A0A2K4BUX3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

29379:I6G39 RS03415
gene id: 29379:I6G39_RS03415
uniprot id: A0A2K4C3M4
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

29379:I6G39 RS02545
gene id: 29379:I6G39_RS02545
uniprot id: A0A2K4C0G2
names: Similarity
messages: Belongs to the AHA1 family.

29379:I6G39 RS05135
gene id: 29379:I6G39_RS05135
uniprot id: A0A2K4BVU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

29379:I6G39 RS09110
gene id: 29379:I6G39_RS09110
uniprot id: A0A2K4C4H6
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

29379:I6G39 RS08060
gene id: 29379:I6G39_RS08060
uniprot id: A0A2K4C260
names: Similarity
messages: Belongs to the acyltransferase 3 family.

29379:I6G39 RS07025
gene id: 29379:I6G39_RS07025
uniprot id: A0A2K4C4P6
names: Function
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.

29379:I6G39 RS00060
gene id: 29379:I6G39_RS00060
uniprot id: A0A2K4C230
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS03120
gene id: 29379:I6G39_RS03120
uniprot id: A0A2K4BY54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

29379:I6G39 RS06540
gene id: 29379:I6G39_RS06540
uniprot id: A0A2K4BWV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

29379:I6G39 RS07290
gene id: 29379:I6G39_RS07290
uniprot id: A0A2K4C375
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

29379:I6G39 RS04510
gene id: 29379:I6G39_RS04510
uniprot id: A0A2K4BWP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

29379:I6G39 RS03700
gene id: 29379:I6G39_RS03700
uniprot id: A0A2K4C2G3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

29379:I6G39 RS09755
gene id: 29379:I6G39_RS09755
uniprot id: A0A2K4BXQ0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

29379:I6G39 RS09260
gene id: 29379:I6G39_RS09260
uniprot id: A0A2K4C481
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer or homotrimer. Seems to be a monomer when not phosphorylated.
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

29379:I6G39 RS06910
gene id: 29379:I6G39_RS06910
uniprot id: A0A2K4C4V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

29379:I6G39 RS07165
gene id: 29379:I6G39_RS07165
uniprot id: A0A2K4BZ78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

29379:I6G39 RS01290
gene id: 29379:I6G39_RS01290
uniprot id: A0A2K4BW32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

29379:I6G39 RS04185
gene id: 29379:I6G39_RS04185
uniprot id: A0A2K4BZQ9
names: Similarity
messages: Belongs to the UPF0374 family.

29379:I6G39 RS03455
gene id: 29379:I6G39_RS03455
uniprot id: A0A2K4C3L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

29379:I6G39 RS09225
gene id: 29379:I6G39_RS09225
uniprot id: A0A2K4C4B0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS01645
gene id: 29379:I6G39_RS01645
uniprot id: A0A2K4BYH1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

29379:I6G39 RS02600
gene id: 29379:I6G39_RS02600
uniprot id: A0A2K4C0E3
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS08035
gene id: 29379:I6G39_RS08035
uniprot id: A0A2K4C2M0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

29379:I6G39 RS01070
gene id: 29379:I6G39_RS01070
uniprot id: A0A2K4BVF1
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

29379:I6G39 RS10020
gene id: 29379:I6G39_RS10020
uniprot id: A0A2K4BZ65
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

29379:I6G39 RS05880
gene id: 29379:I6G39_RS05880
uniprot id: A0A2K4BUZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

29379:I6G39 RS03015
gene id: 29379:I6G39_RS03015
uniprot id: A0A2K4C059
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

29379:I6G39 RS07465
gene id: 29379:I6G39_RS07465
uniprot id: A0A2K4C3D2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

29379:I6G39 RS08785
gene id: 29379:I6G39_RS08785
uniprot id: A0A2K4BZE8
names: Similarity
messages: Belongs to the OsmC/Ohr family.

29379:I6G39 RS03465
gene id: 29379:I6G39_RS03465
uniprot id: A0A2K4C3L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

29379:I6G39 RS09885
gene id: 29379:I6G39_RS09885
uniprot id: A0A2K4BYK4
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

29379:I6G39 RS00250
gene id: 29379:I6G39_RS00250
uniprot id: A0A2K4BW98
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

29379:I6G39 RS07960
gene id: 29379:I6G39_RS07960
uniprot id: A0A2K4C170
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS07425
gene id: 29379:I6G39_RS07425
uniprot id: A0A2K4C339
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

29379:I6G39 RS07610
gene id: 29379:I6G39_RS07610
uniprot id: A0A2K4BU56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

29379:I6G39 RS05975
gene id: 29379:I6G39_RS05975
uniprot id: A0A2K4BV25
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

29379:I6G39 RS07270
gene id: 29379:I6G39_RS07270
uniprot id: A0A2K4C369
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

29379:I6G39 RS10405
gene id: 29379:I6G39_RS10405
uniprot id: A0A2K4C1F5
names: Similarity
names: Subunit
messages: Belongs to the azoreductase type 2 family.
messages: Homotetramer.

29379:I6G39 RS04935
gene id: 29379:I6G39_RS04935
uniprot id: A0A2K4C430
names: Similarity
messages: Belongs to the UPF0354 family.

29379:I6G39 RS03480
gene id: 29379:I6G39_RS03480
uniprot id: A0A2K4C3T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

29379:I6G39 RS00490
gene id: 29379:I6G39_RS00490
uniprot id: A0A2K4BTU5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

29379:I6G39 RS07725
gene id: 29379:I6G39_RS07725
uniprot id: A0A2K4BU46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

29379:I6G39 RS08630
gene id: 29379:I6G39_RS08630
uniprot id: A0A2K4BUF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS06250
gene id: 29379:I6G39_RS06250
uniprot id: A0A2K4C2W4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

29379:I6G39 RS03025
gene id: 29379:I6G39_RS03025
uniprot id: A0A2K4C064
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

29379:I6G39 RS02755
gene id: 29379:I6G39_RS02755
uniprot id: A0A2K4C0A6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

29379:I6G39 RS04180
gene id: 29379:I6G39_RS04180
uniprot id: A0A2K4BZU6
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

29379:I6G39 RS03585
gene id: 29379:I6G39_RS03585
uniprot id: A0A2K4C3P5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

29379:I6G39 RS07950
gene id: 29379:I6G39_RS07950
uniprot id: A0A2K4C156
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29379:I6G39 RS06260
gene id: 29379:I6G39_RS06260
uniprot id: A0A2K4C322
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

29379:I6G39 RS07875
gene id: 29379:I6G39_RS07875
uniprot id: A0A2K4BV92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS08970
gene id: 29379:I6G39_RS08970
uniprot id: A0A2K4C4I6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

29379:I6G39 RS08485
gene id: 29379:I6G39_RS08485
uniprot id: A0A2K4C2W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

29379:I6G39 RS01470
gene id: 29379:I6G39_RS01470
uniprot id: A0A2K4BYW4
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

29379:I6G39 RS10255
gene id: 29379:I6G39_RS10255
uniprot id: A0A2K4BX29
names: Subcellular Location Annotation
messages: cell wall

29379:I6G39 RS04885
gene id: 29379:I6G39_RS04885
uniprot id: A0A2K4C418
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

29379:I6G39 RS09635
gene id: 29379:I6G39_RS09635
uniprot id: A0A2K4C2T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS09505
gene id: 29379:I6G39_RS09505
uniprot id: A0A2K4BXE2
names: Function
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.

29379:I6G39 RS03125
gene id: 29379:I6G39_RS03125
uniprot id: A0A2K4BY44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

29379:I6G39 RS08475
gene id: 29379:I6G39_RS08475
uniprot id: A0A2K4C439
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Cell membrane
messages: May form a heterooligomeric complex that consists of seven subunits: mnhA1, mnhB1, mnhC1, mnhD1, mnhE1, mnhF1 and mnhG1.
messages: Membrane

29379:I6G39 RS05435
gene id: 29379:I6G39_RS05435
uniprot id: A0A2K4BX07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.
messages: Probably involved in cell-wall metabolism.
messages: Secreted

29379:I6G39 RS09545
gene id: 29379:I6G39_RS09545
uniprot id: A0A2K4C1M5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

29379:I6G39 RS06460
gene id: 29379:I6G39_RS06460
uniprot id: A0A2K4BX59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Essential for cell viability.
messages: Membrane

29379:I6G39 RS02020
gene id: 29379:I6G39_RS02020
uniprot id: A0A2K4C2Q7
names: Similarity
messages: Belongs to the UPF0741 family.

29379:I6G39 RS06725
gene id: 29379:I6G39_RS06725
uniprot id: A0A2K4C4V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

29379:I6G39 RS08490
gene id: 29379:I6G39_RS08490
uniprot id: A0A2K4C2Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Cell membrane
messages: Membrane

29379:I6G39 RS05805
gene id: 29379:I6G39_RS05805
uniprot id: A0A2K4BUX8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

29379:I6G39 RS08550
gene id: 29379:I6G39_RS08550
uniprot id: A0A2K4C4Z3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

29379:I6G39 RS07445
gene id: 29379:I6G39_RS07445
uniprot id: A0A2K4C337
names: Subcellular Location Annotation
messages: Cytoplasm

29379:I6G39 RS02210
gene id: 29379:I6G39_RS02210
uniprot id: A0A2K4C2L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CidB/LrgB family. LrgB subfamily.
messages: Cell membrane
messages: Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and/or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
messages: Membrane

29379:I6G39 RS00850
gene id: 29379:I6G39_RS00850
uniprot id: A0A2K4BVI0
names: Subcellular Location Annotation
messages: Membrane

29379:I6G39 RS05420
gene id: 29379:I6G39_RS05420
uniprot id: A0A2K4BWZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

29379:I6G39 RS09840
gene id: 29379:I6G39_RS09840
uniprot id: A0A2K4BYI5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

29379:I6G39 RS00330
gene id: 29379:I6G39_RS00330
uniprot id: A0A2K4BXN6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

29379:I6G39 RS02645
gene id: 29379:I6G39_RS02645
uniprot id: A0A2K4C0C3
names: Similarity
messages: In the N-terminal section; belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.