29088:PLAG1
gene id: 29088:PLAG1
uniprot id: A0A2Y9GY39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

29088:TECR
gene id: 29088:TECR
uniprot id: A0A2Y9IC51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:EFHC1
gene id: 29088:EFHC1
uniprot id: A0A2Y9H7T7
names: Subcellular Location Annotation
messages: cilium axoneme

29088:RETREG1
gene id: 29088:RETREG1
uniprot id: A0A2Y9I365
uniprot id: A0A2Y9I7K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Membrane

29088:LOC110579605
gene id: 29088:LOC110579605
uniprot id: A0A2Y9H044
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide.
messages: Secreted
messages: When bound to LPS, interacts (via C-terminus) with soluble and membrane-bound CD14.

29088:OPA1
gene id: 29088:OPA1
uniprot id: A0A8M1MSZ0
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

29088:LOC110575569
gene id: 29088:LOC110575569
uniprot id: A0A2Y9GQU7
names: Similarity
messages: Belongs to the MHC class II family.

29088:B3GALT2
gene id: 29088:B3GALT2
uniprot id: A0A2Y9GSS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:LOC110574961
gene id: 29088:LOC110574961
uniprot id: A0A2Y9GQ62
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110573992
gene id: 29088:LOC110573992
uniprot id: A0A8M1MI89
names: Subcellular Location Annotation
messages: Nucleus

29088:GNB4
gene id: 29088:GNB4
uniprot id: A0A2Y9H8U1
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

29088:LOC110584592
gene id: 29088:LOC110584592
uniprot id: A0A2Y9HFG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

29088:LOC123324064
gene id: 29088:LOC123324064
uniprot id: A0A2Y9GLQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SERPINE2
gene id: 29088:SERPINE2
uniprot id: A0A2Y9GHK4
names: Similarity
messages: Belongs to the serpin family.

29088:MTX1
gene id: 29088:MTX1
uniprot id: A0A8M1MH65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

29088:LOC110592277
gene id: 29088:LOC110592277
uniprot id: A0A8M1M670
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

29088:LUM
gene id: 29088:LUM
uniprot id: A0A2Y9GVG1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to laminin.
messages: extracellular matrix

29088:ME2
gene id: 29088:ME2
uniprot id: A0A2Y9GXM3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

29088:TMSB10
gene id: 29088:TMSB10
uniprot id: A0A2Y9HUZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

29088:STRN4
gene id: 29088:STRN4
uniprot id: A0A2Y9GD71
uniprot id: A0A2Y9GDB7
uniprot id: A0A2Y9GDD2
uniprot id: A0A8M1MY65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

29088:NCL
gene id: 29088:NCL
uniprot id: A0A2Y9H304
uniprot id: A0A2Y9H814
uniprot id: A0A8M1M692
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.
messages: nucleolus

29088:ICAM3
gene id: 29088:ICAM3
uniprot id: A0A2Y9IAC6
uniprot id: A0A2Y9IAF6
uniprot id: A0A8M1MMS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

29088:CEBPZ
gene id: 29088:CEBPZ
uniprot id: A0A2Y9HN19
uniprot id: A0A8M1MPH1
names: Similarity
messages: Belongs to the CBF/MAK21 family.

29088:LOC110572930
gene id: 29088:LOC110572930
uniprot id: A0A2Y9GD80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

29088:UFC1
gene id: 29088:UFC1
uniprot id: A0A2Y9GF69
names: Function
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
messages: E1-like enzyme which specifically catalyzes the second step in ufmylation. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

29088:LOC110590740
gene id: 29088:LOC110590740
uniprot id: A0A8M1MD34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

29088:MUTYH
gene id: 29088:MUTYH
uniprot id: A0A2Y9GNP0
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

29088:CIBAR2
gene id: 29088:CIBAR2
uniprot id: A0A8M1MVX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIBAR family.
messages: centriole
messages: cilium basal body

29088:ADD1
gene id: 29088:ADD1
uniprot id: A0A8M1M532
uniprot id: A0A8M1M7H4
uniprot id: A0A8M1M8Z0
uniprot id: A0A8M1MD59
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

29088:LOC110576506
gene id: 29088:LOC110576506
uniprot id: A0A2Y9GQA8
names: Subcellular Location Annotation
messages: Membrane

29088:MON2
gene id: 29088:MON2
uniprot id: A0A2Y9G873
uniprot id: A0A8M1MBY4
uniprot id: A0A8M1MFG2
names: Similarity
messages: Belongs to the MON2 family.

29088:DMAP1
gene id: 29088:DMAP1
uniprot id: A0A8M1MA96
names: Subcellular Location Annotation
messages: Nucleus

29088:INSL3
gene id: 29088:INSL3
uniprot id: A0A2Y9GLF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted
messages: Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.

29088:SLC8B1
gene id: 29088:SLC8B1
uniprot id: A0A2Y9HR34
uniprot id: A0A2Y9HWC1
uniprot id: A0A8M1MYS0
names: Subcellular Location Annotation
messages: Membrane

29088:ABHD12
gene id: 29088:ABHD12
uniprot id: A0A2Y9I472
uniprot id: A0A8M1MLE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serine esterase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:BCKDK
gene id: 29088:BCKDK
uniprot id: A0A2Y9HXK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

29088:SIDT1
gene id: 29088:SIDT1
uniprot id: A0A2Y9H8P7
uniprot id: A0A2Y9H8S9
uniprot id: A0A2Y9H8X4
uniprot id: A0A2Y9HEG7
uniprot id: A0A2Y9HFH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

29088:CASKIN1
gene id: 29088:CASKIN1
uniprot id: A0A2Y9HWI4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

29088:TUBB2A
gene id: 29088:TUBB2A
uniprot id: A0A2Y9HSJ0
uniprot id: A0A8M1MI00
uniprot id: A0A8M1MI01
uniprot id: A0A8M1MI05
uniprot id: A0A8M1MK27
uniprot id: A0A8M1MLD5
uniprot id: A0A8M1MRY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

29088:LOC110576011
gene id: 29088:LOC110576011
uniprot id: A0A2Y9GU33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110585694
gene id: 29088:LOC110585694
uniprot id: A0A2Y9HIA5
names: Similarity
messages: Belongs to the importin alpha family.

29088:PLPP3
gene id: 29088:PLPP3
uniprot id: A0A2Y9GLM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

29088:LOC110583360
gene id: 29088:LOC110583360
uniprot id: A0A2Y9HBG4
uniprot id: A0A8M1MHJ7
uniprot id: A0A8M1MKX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Binds with high affinity to IPO4. Interacts with DDIT3.
messages: Cytoplasm
messages: May play a role during erythropoiesis through regulation of transcription factor DDIT3.
messages: Nucleus

29088:SLC37A3
gene id: 29088:SLC37A3
uniprot id: A0A2Y9HGP7
uniprot id: A0A8M1MPW4
uniprot id: A0A8M1MRR9
uniprot id: A0A8M1MT50
uniprot id: A0A8M1MY45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

29088:ACR
gene id: 29088:ACR
uniprot id: A0A2Y9H0G6
names: Function
names: Similarity
names: Subunit
messages: Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome.
messages: Belongs to the peptidase S1 family.
messages: Heavy chain (catalytic) and a light chain linked by two disulfide bonds. Forms a heterodimer with SERPINA5.

29088:ZKSCAN7
gene id: 29088:ZKSCAN7
uniprot id: A0A8M1MBZ6
names: Subcellular Location Annotation
messages: Nucleus

29088:PNLIPRP1
gene id: 29088:PNLIPRP1
uniprot id: A0A2Y9I1V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

29088:CCN2
gene id: 29088:CCN2
uniprot id: A0A2Y9HB05
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:MAP2K1
gene id: 29088:MAP2K1
uniprot id: A0A2Y9HDF9
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:MEOX1
gene id: 29088:MEOX1
uniprot id: A0A2Y9GE18
uniprot id: A0A2Y9GH53
names: Subcellular Location Annotation
messages: Nucleus

29088:MANEAL
gene id: 29088:MANEAL
uniprot id: A0A2Y9GNA9
uniprot id: A0A2Y9GPZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:LOC110569679
gene id: 29088:LOC110569679
uniprot id: A0A8M1MSF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Filament-forming cytoskeletal GTPase.
messages: Midbody
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: cilium axoneme
messages: flagellum
messages: kinetochore
messages: spindle

29088:BNIP3L
gene id: 29088:BNIP3L
uniprot id: A0A2Y9HSI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

29088:LOC110591787
gene id: 29088:LOC110591787
uniprot id: A0A2Y9I331
uniprot id: A0A2Y9I3D0
uniprot id: A0A2Y9I3M6
uniprot id: A0A2Y9IA41
uniprot id: A0A8M1M689
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

29088:SCAND1
gene id: 29088:SCAND1
uniprot id: A0A2Y9GZS6
names: Subcellular Location Annotation
messages: Nucleus

29088:TMEM106A
gene id: 29088:TMEM106A
uniprot id: A0A2Y9GE23
names: Similarity
messages: Belongs to the TMEM106 family.

29088:RDH8
gene id: 29088:RDH8
uniprot id: A0A2Y9IIF9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:PHLDA3
gene id: 29088:PHLDA3
uniprot id: A0A2Y9GL81
names: Subcellular Location Annotation
messages: Cytoplasm

29088:DDX52
gene id: 29088:DDX52
uniprot id: A0A2Y9IBU7
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.

29088:LOC110584389
gene id: 29088:LOC110584389
uniprot id: A0A2Y9HEE0
uniprot id: A0A2Y9HEM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

29088:SSTR1
gene id: 29088:SSTR1
uniprot id: A0A2Y9I4P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:LOC110583116
gene id: 29088:LOC110583116
uniprot id: A0A2Y9HAS3
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

29088:LOC110572060
gene id: 29088:LOC110572060
uniprot id: A0A2Y9GAE2
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

29088:CDK15
gene id: 29088:CDK15
uniprot id: A0A2Y9I4M8
uniprot id: A0A2Y9I9E7
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:RPS6KA3
gene id: 29088:RPS6KA3
uniprot id: A0A2Y9GFH9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

29088:LOC110586433
gene id: 29088:LOC110586433
uniprot id: A0A2Y9HKX5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110576908
gene id: 29088:LOC110576908
uniprot id: A0A2Y9GRI4
uniprot id: A0A2Y9GRL7
uniprot id: A0A8M1MVM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

29088:LTBP1
gene id: 29088:LTBP1
uniprot id: A0A2Y9HNN5
uniprot id: A0A8M1MLH5
uniprot id: A0A8M1MLH9
uniprot id: A0A8M1MLI4
uniprot id: A0A8M1MLI6
uniprot id: A0A8M1MLI9
uniprot id: A0A8M1MLJ2
uniprot id: A0A8M1MLJ4
uniprot id: A0A8M1MLJ7
uniprot id: A0A8M1MLJ9
uniprot id: A0A8M1MNH1
uniprot id: A0A8M1MNH7
uniprot id: A0A8M1MNI1
uniprot id: A0A8M1MNI6
uniprot id: A0A8M1MNJ1
uniprot id: A0A8M1MPS8
uniprot id: A0A8M1MPT3
uniprot id: A0A8M1MPT7
uniprot id: A0A8M1MPU2
uniprot id: A0A8M1MPU7
uniprot id: A0A8M1MVN7
uniprot id: A0A8M1MVP2
uniprot id: A0A8M1MVP7
uniprot id: A0A8M1MVQ2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:NLK
gene id: 29088:NLK
uniprot id: A0A2Y9I722
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

29088:TNFRSF19
gene id: 29088:TNFRSF19
uniprot id: A0A2Y9G4P0
uniprot id: A0A2Y9G4R1
uniprot id: A0A2Y9G556
uniprot id: A0A2Y9G8A7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ACTL8
gene id: 29088:ACTL8
uniprot id: A0A2Y9GMP0
names: Similarity
messages: Belongs to the actin family.

29088:LOC123323383
gene id: 29088:LOC123323383
uniprot id: A0A8M1M1B6
names: Similarity
messages: Belongs to the Gfa family.

29088:C6H10orf53
gene id: 29088:C6H10orf53
uniprot id: A0A2Y9I2K0
names: Similarity
messages: Belongs to the UPF0728 family.

29088:DENND11
gene id: 29088:DENND11
uniprot id: A0A8M1MS69
names: Similarity
messages: Belongs to the DENND11 family.

29088:TTLL9
gene id: 29088:TTLL9
uniprot id: A0A2Y9GZW0
names: Similarity
messages: Belongs to the tubulin--tyrosine ligase family.

29088:RARRES2
gene id: 29088:RARRES2
uniprot id: A0A2Y9HA36
names: Subcellular Location Annotation
messages: Secreted

29088:GUCA2B
gene id: 29088:GUCA2B
uniprot id: A0A2Y9GQI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

29088:GSK3B
gene id: 29088:GSK3B
uniprot id: A0A2Y9H9J4
uniprot id: A0A2Y9H9Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
messages: Cytoplasm
messages: Nucleus

29088:AKAP8L
gene id: 29088:AKAP8L
uniprot id: A0A2Y9GIH0
uniprot id: A0A2Y9GLX2
uniprot id: A0A8M1M5I4
names: Similarity
messages: Belongs to the AKAP95 family.

29088:CAMK2D
gene id: 29088:CAMK2D
uniprot id: A0A2Y9GLZ5
uniprot id: A0A2Y9GM54
uniprot id: A0A8M1M4N2
uniprot id: A0A8M1M4N7
uniprot id: A0A8M1M4Y4
uniprot id: A0A8M1M734
uniprot id: A0A8M1M739
uniprot id: A0A8M1M8K2
uniprot id: A0A8M1MCP6
uniprot id: A0A8M1MCQ2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

29088:VBP1
gene id: 29088:VBP1
uniprot id: A0A2Y9GGR8
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

29088:EXOSC3
gene id: 29088:EXOSC3
uniprot id: A0A2Y9HD48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm

29088:CLCF1
gene id: 29088:CLCF1
uniprot id: A0A2Y9GSH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

29088:PLCG2
gene id: 29088:PLCG2
uniprot id: A0A2Y9IHT4
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

29088:C3
gene id: 29088:C3
uniprot id: A0A2Y9IBQ0
names: Function
names: Subcellular Location Annotation
messages: Acts as a chemoattractant for neutrophils in chronic inflammation.
messages: C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
messages: Secreted

29088:ZRANB1
gene id: 29088:ZRANB1
uniprot id: A0A2Y9I641
uniprot id: A0A8M1MHM8
names: Similarity
messages: Belongs to the peptidase C64 family.

29088:PTGES3L
gene id: 29088:PTGES3L
uniprot id: A0A8M1MV86
names: Similarity
messages: Belongs to the p23/wos2 family.

29088:LOC110582919
gene id: 29088:LOC110582919
uniprot id: A0A8M1MQB8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

29088:LOC110586875
gene id: 29088:LOC110586875
uniprot id: A0A2Y9HLH7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:LIPG
gene id: 29088:LIPG
uniprot id: A0A2Y9GRW6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:ZPR1
gene id: 29088:ZPR1
uniprot id: A0A2Y9HJX0
uniprot id: A0A8M1MN60
names: Similarity
messages: Belongs to the ZPR1 family.

29088:TSEN54
gene id: 29088:TSEN54
uniprot id: A0A2Y9GCH0
names: Similarity
messages: Belongs to the SEN54 family.

29088:RORC
gene id: 29088:RORC
uniprot id: A0A8M1M8D5
uniprot id: A0A8M1M8M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

29088:GTF2F1
gene id: 29088:GTF2F1
uniprot id: A0A2Y9IAG7
uniprot id: A0A2Y9IEA3
uniprot id: A0A2Y9IH12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

29088:PTGFR
gene id: 29088:PTGFR
uniprot id: A0A2Y9H2P4
uniprot id: A0A2Y9H2Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:LOC110570235
gene id: 29088:LOC110570235
uniprot id: A0A8M1MDR3
names: Similarity
messages: Belongs to the SKP1 family.

29088:LOC110583429
gene id: 29088:LOC110583429
uniprot id: A0A2Y9HBU4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

29088:ASZ1
gene id: 29088:ASZ1
uniprot id: A0A2Y9HYV1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with DDX4, PIWIL1, RANBP9 and TDRD1.
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

29088:LOC110572787
gene id: 29088:LOC110572787
uniprot id: A0A8M1M1T0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

29088:LOC123325490
gene id: 29088:LOC123325490
uniprot id: A0A8M1MHC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus

29088:MCEE
gene id: 29088:MCEE
uniprot id: A0A2Y9GF49
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

29088:LOC123324876
gene id: 29088:LOC123324876
uniprot id: A0A2Y9HKK2
names: Similarity
messages: Belongs to the GroES chaperonin family.

29088:FMOD
gene id: 29088:FMOD
uniprot id: A0A2Y9GSN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis.
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to type I and type II collagen.
messages: extracellular matrix

29088:LOC110588386
gene id: 29088:LOC110588386
uniprot id: A0A2Y9HYJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Forms the cluster TLR2:TLR6:CD14:CD36 in response to diacylated lipopeptides and TLR2:TLR1:CD14 in response to triacylated lipopeptides.
messages: Membrane raft
messages: phagosome membrane

29088:IGF2BP1
gene id: 29088:IGF2BP1
uniprot id: A0A2Y9I7F1
uniprot id: A0A2Y9I7Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Nucleus
messages: P-body
messages: Stress granule
messages: filopodium
messages: growth cone
messages: lamellipodium
messages: perinuclear region

29088:MAU2
gene id: 29088:MAU2
uniprot id: A0A2Y9GLS7
uniprot id: A0A2Y9GNL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC4/mau-2 family.
messages: nucleoplasm

29088:F8
gene id: 29088:F8
uniprot id: A0A2Y9GH62
names: Similarity
messages: Belongs to the multicopper oxidase family.

29088:IFI35
gene id: 29088:IFI35
uniprot id: A0A8M1MWK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NMI family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

29088:CGAS
gene id: 29088:CGAS
uniprot id: A0A2Y9HBQ0
names: Similarity
messages: Belongs to the mab-21 family.

29088:DMTN
gene id: 29088:DMTN
uniprot id: A0A2Y9HS18
uniprot id: A0A8M1M3F4
uniprot id: A0A8M1M5X6
uniprot id: A0A8M1M7F4
uniprot id: A0A8M1M7H0
uniprot id: A0A8M1MBE0
uniprot id: A0A8M1MBF7
uniprot id: A0A8M1MBG3
names: Subcellular Location Annotation
messages: Cytoplasm

29088:ATP13A3
gene id: 29088:ATP13A3
uniprot id: A0A2Y9H9S0
uniprot id: A0A8M1MPP6
uniprot id: A0A8M1MPQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

29088:LOC110582141
gene id: 29088:LOC110582141
uniprot id: A0A8M1MHX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

29088:LOC110573126
gene id: 29088:LOC110573126
uniprot id: A0A8M1M4D0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:DYNC1I2
gene id: 29088:DYNC1I2
uniprot id: A0A2Y9I5N0
uniprot id: A0A8M1M9B3
uniprot id: A0A8M1MAQ1
uniprot id: A0A8M1MF51
names: Similarity
messages: Belongs to the dynein intermediate chain family.

29088:TMEM245
gene id: 29088:TMEM245
uniprot id: A0A8M1MRM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

29088:LOC110584488
gene id: 29088:LOC110584488
uniprot id: A0A2Y9HL38
names: Similarity
messages: Belongs to the tumor necrosis factor family.

29088:ALDH2
gene id: 29088:ALDH2
uniprot id: A0A2Y9HWD2
uniprot id: A0A8M1MW91
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

29088:LOC110583170
gene id: 29088:LOC110583170
uniprot id: A0A2Y9HGZ4
names: Similarity
messages: Belongs to the nesprin family.

29088:GNB1
gene id: 29088:GNB1
uniprot id: A0A2Y9GP52
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

29088:LPAR2
gene id: 29088:LPAR2
uniprot id: A0A2Y9GHY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:KITLG
gene id: 29088:KITLG
uniprot id: A0A2Y9GVF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCF family.
messages: Cytoplasm
messages: Homodimer, non-covalently linked.
messages: Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis.
messages: Secreted
messages: filopodium
messages: lamellipodium

29088:DOC2B
gene id: 29088:DOC2B
uniprot id: A0A2Y9I7L0
names: Subcellular Location Annotation
messages: Membrane

29088:ESYT1
gene id: 29088:ESYT1
uniprot id: A0A2Y9GUL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:MIGA2
gene id: 29088:MIGA2
uniprot id: A0A2Y9HAQ6
names: Similarity
messages: Belongs to the mitoguardin family.

29088:ST8SIA4
gene id: 29088:ST8SIA4
uniprot id: A0A2Y9HTB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

29088:HSPB3
gene id: 29088:HSPB3
uniprot id: A0A2Y9HLK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Nucleus

29088:VIM
gene id: 29088:VIM
uniprot id: A0A2Y9HSR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Cell membrane
messages: Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.
messages: Membrane
messages: Nucleus matrix
messages: Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.

29088:HCN1
gene id: 29088:HCN1
uniprot id: A0A2Y9HH92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

29088:LOC110591614
gene id: 29088:LOC110591614
uniprot id: A0A2Y9I2N0
names: Subcellular Location Annotation
messages: Nucleus

29088:EIF3K
gene id: 29088:EIF3K
uniprot id: A0A2Y9HYM4
uniprot id: A0A2Y9I3J9
uniprot id: A0A8M1M0Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit K family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with CCND3, but not with CCND1 and CCND2.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Nucleus

29088:LOC123326208
gene id: 29088:LOC123326208
uniprot id: A0A8M1MNS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SSTR4
gene id: 29088:SSTR4
uniprot id: A0A2Y9HXL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:LOC110576125
gene id: 29088:LOC110576125
uniprot id: A0A2Y9GNS5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:DNMT3A
gene id: 29088:DNMT3A
uniprot id: A0A2Y9HNR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

29088:PRKACB
gene id: 29088:PRKACB
uniprot id: A0A2Y9H9M4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

29088:COPB2
gene id: 29088:COPB2
uniprot id: A0A2Y9G6M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

29088:SLC6A11
gene id: 29088:SLC6A11
uniprot id: A0A2Y9HFT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

29088:A4GALT
gene id: 29088:A4GALT
uniprot id: A0A2Y9H092
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

29088:NAP1L1
gene id: 29088:NAP1L1
uniprot id: A0A2Y9G5L9
uniprot id: A0A2Y9G5M1
uniprot id: A0A2Y9G615
uniprot id: A0A2Y9G981
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

29088:TACC1
gene id: 29088:TACC1
uniprot id: A0A2Y9GGT8
uniprot id: A0A8M1M2D7
uniprot id: A0A8M1M2E2
uniprot id: A0A8M1M2F4
uniprot id: A0A8M1M2H9
uniprot id: A0A8M1M2N5
uniprot id: A0A8M1M2U0
uniprot id: A0A8M1M4Y2
uniprot id: A0A8M1M4Z7
uniprot id: A0A8M1M515
uniprot id: A0A8M1M520
uniprot id: A0A8M1MAB0
uniprot id: A0A8M1MAC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

29088:CD99L2
gene id: 29088:CD99L2
uniprot id: A0A8M1M3V2
uniprot id: A0A8M1M5E0
uniprot id: A0A8M1M956
names: Similarity
messages: Belongs to the CD99 family.

29088:OOSP2
gene id: 29088:OOSP2
uniprot id: A0A2Y9GP20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLAC1 family.
messages: Secreted

29088:ZNF213
gene id: 29088:ZNF213
uniprot id: A0A2Y9HVS3
uniprot id: A0A2Y9HXB7
names: Subcellular Location Annotation
messages: Nucleus

29088:EXOC2
gene id: 29088:EXOC2
uniprot id: A0A8M1MIE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

29088:RPP14
gene id: 29088:RPP14
uniprot id: A0A2Y9HGC1
uniprot id: A0A2Y9HM91
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

29088:SLC9A5
gene id: 29088:SLC9A5
uniprot id: A0A2Y9I5Z0
uniprot id: A0A2Y9I6T2
uniprot id: A0A2Y9IAU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Membrane

29088:SERPINA3
gene id: 29088:SERPINA3
uniprot id: A0A8M1MMZ7
names: Similarity
messages: Belongs to the serpin family.

29088:GPR17
gene id: 29088:GPR17
uniprot id: A0A2Y9HIW7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:GALNT9
gene id: 29088:GALNT9
uniprot id: A0A8M1MYU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:GRPEL1
gene id: 29088:GRPEL1
uniprot id: A0A2Y9G2N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

29088:OCA2
gene id: 29088:OCA2
uniprot id: A0A2Y9GDK8
names: Subcellular Location Annotation
messages: Membrane

29088:TRPM2
gene id: 29088:TRPM2
uniprot id: A0A2Y9G758
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM2 sub-subfamily.
messages: Cell membrane
messages: Membrane

29088:LOC110589006
gene id: 29088:LOC110589006
uniprot id: A0A8M1MQE4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

29088:LOC110571177
gene id: 29088:LOC110571177
uniprot id: A0A8M1MQU7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

29088:LOC110571130
gene id: 29088:LOC110571130
uniprot id: A0A8M1M1Y1
names: Similarity
messages: Belongs to the Gfa family.

29088:LOC110586870
gene id: 29088:LOC110586870
uniprot id: A0A2Y9HM82
uniprot id: A0A2Y9HSR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:RFC4
gene id: 29088:RFC4
uniprot id: A0A2Y9HFX6
names: Similarity
messages: Belongs to the activator 1 small subunits family.

29088:NAGK
gene id: 29088:NAGK
uniprot id: A0A2Y9HSI8
uniprot id: A0A2Y9HT19
uniprot id: A0A2Y9HZG4
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

29088:MRPS25
gene id: 29088:MRPS25
uniprot id: A0A2Y9HMA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

29088:LTB4R
gene id: 29088:LTB4R
uniprot id: A0A2Y9HHI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:LASP1
gene id: 29088:LASP1
uniprot id: A0A2Y9I7H6
names: Function
names: Subcellular Location Annotation
messages: Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types.
messages: cell cortex
messages: cytoskeleton

29088:MED15
gene id: 29088:MED15
uniprot id: A0A2Y9GW65
uniprot id: A0A8M1MVP5
uniprot id: A0A8M1MYQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 15 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

29088:CLK3
gene id: 29088:CLK3
uniprot id: A0A2Y9HJE4
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:RGN
gene id: 29088:RGN
uniprot id: A0A2Y9G743
uniprot id: A0A2Y9G7G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

29088:FOXB2
gene id: 29088:FOXB2
uniprot id: A0A2Y9H5A3
names: Subcellular Location Annotation
messages: Nucleus

29088:MAP3K12
gene id: 29088:MAP3K12
uniprot id: A0A2Y9GX37
uniprot id: A0A2Y9GYR8
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: May be an activator of the JNK/SAPK pathway.

29088:TBX21
gene id: 29088:TBX21
uniprot id: A0A2Y9I803
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

29088:LOC110577079
gene id: 29088:LOC110577079
uniprot id: A0A8M1MWN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

29088:LOC110581815
gene id: 29088:LOC110581815
uniprot id: A0A2Y9HCD6
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:GPN3
gene id: 29088:GPN3
uniprot id: A0A2Y9HRF6
uniprot id: A0A8M1MVP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

29088:RPL10A
gene id: 29088:RPL10A
uniprot id: A0A2Y9GM70
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

29088:GHITM
gene id: 29088:GHITM
uniprot id: A0A2Y9HW99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

29088:MFSD14B
gene id: 29088:MFSD14B
uniprot id: A0A2Y9HKP1
uniprot id: A0A2Y9HKV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

29088:TSPAN10
gene id: 29088:TSPAN10
uniprot id: A0A2Y9GEA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

29088:KATNAL1
gene id: 29088:KATNAL1
uniprot id: A0A2Y9G4H1
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit. Interacts with ASPM; the katanin complex formation KATNA1:KATNB1 is required for the association of ASPM. Interacts with dynein and NDEL1. Associates with the E3 ligase complex containing DYRK2, EDD/UBR5, DDB1 and DCAF1 proteins (EDVP complex). Interacts with KLHL42 (via the kelch domains). Interacts with CUL3; the interaction is enhanced by KLHL42. Interacts with KATNB1 and KATNBL1. Interacts with CAMSAP2 and CAMSAP3; leading to regulate the length of CAMSAP-decorated microtubule stretches.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
messages: Cytoplasm
messages: Interacts with KATNB1 and KATNBL1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Midbody
messages: Phosphorylation by DYRK2 triggers ubiquitination and subsequent degradation.
messages: Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays.
messages: The N-terminus is sufficient for interaction with microtubules, although high affinity binding to microtubules also requires an intact C-terminal domain and ATP, which promotes oligomerization.
messages: Ubiquitinated by the BCR(KLHL42) E3 ubiquitin ligase complex, leading to its proteasomal degradation. Ubiquitinated by the EDVP E3 ligase complex and subsequently targeted for proteasomal degradation.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

29088:GLS
gene id: 29088:GLS
uniprot id: A0A2Y9I929
uniprot id: A0A2Y9IBH6
names: Similarity
messages: Belongs to the glutaminase family.

29088:CLCA2
gene id: 29088:CLCA2
uniprot id: A0A2Y9H2H7
uniprot id: A0A2Y9H2J6
uniprot id: A0A2Y9H2L5
names: Similarity
messages: Belongs to the CLCR family.

29088:PGR
gene id: 29088:PGR
uniprot id: A0A2Y9G6S9
uniprot id: A0A2Y9G994
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Cytoplasm
messages: Nucleus
messages: Steroid hormone receptor involved in the regulation of eukaryotic gene expression which affects cellular proliferation and differentiation in target tissues.

29088:HSPD1
gene id: 29088:HSPD1
uniprot id: A0A2Y9I3Z9
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

29088:LOC110577414
gene id: 29088:LOC110577414
uniprot id: A0A2Y9GT24
names: Similarity
messages: Belongs to the PP3/GlyCAM-1 family.

29088:ENSA
gene id: 29088:ENSA
uniprot id: A0A2Y9H1A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

29088:RAP2A
gene id: 29088:RAP2A
uniprot id: A0A2Y9HJ05
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

29088:CLIC1
gene id: 29088:CLIC1
uniprot id: A0A2Y9HSL2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cell membrane
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane
messages: Nucleus membrane

29088:AKIRIN1
gene id: 29088:AKIRIN1
uniprot id: A0A2Y9GK01
uniprot id: A0A8M1M7S6
uniprot id: A0A8M1M816
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

29088:PIWIL2
gene id: 29088:PIWIL2
uniprot id: A0A2Y9HXH7
uniprot id: A0A2Y9HZ17
names: Similarity
messages: Belongs to the argonaute family.

29088:LCTL
gene id: 29088:LCTL
uniprot id: A0A2Y9HJP6
uniprot id: A0A8M1MLR5
uniprot id: A0A8M1MTS1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

29088:FAM20C
gene id: 29088:FAM20C
uniprot id: A0A2Y9GDV3
names: Similarity
messages: Belongs to the FAM20 family.

29088:RTCA
gene id: 29088:RTCA
uniprot id: A0A8M1MAG6
uniprot id: A0A8M1MBU7
uniprot id: A0A8M1MGD9
names: Function
names: Similarity
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.

29088:CCDC22
gene id: 29088:CCDC22
uniprot id: A0A8M1M1E0
uniprot id: A0A8M1M3X2
names: Similarity
messages: Belongs to the CCDC22 family.

29088:SLC27A2
gene id: 29088:SLC27A2
uniprot id: A0A2Y9HCU9
uniprot id: A0A2Y9HJD6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

29088:ANP32B
gene id: 29088:ANP32B
uniprot id: A0A2Y9H5I2
names: Similarity
messages: Belongs to the ANP32 family.

29088:CLDN20
gene id: 29088:CLDN20
uniprot id: A0A2Y9HBT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

29088:IRAK2
gene id: 29088:IRAK2
uniprot id: A0A2Y9HMD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
messages: Interacts with MYD88. IL-1 stimulation leads to the formation of a signaling complex which dissociates from the IL-1 receptor following the binding of PELI1.

29088:PURA
gene id: 29088:PURA
uniprot id: A0A2Y9I5X4
uniprot id: A0A8M1MJJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

29088:UNG
gene id: 29088:UNG
uniprot id: A0A2Y9I6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Monomer. Interacts with FAM72A.
messages: Nucleus

29088:TRPC3
gene id: 29088:TRPC3
uniprot id: A0A2Y9GDR9
uniprot id: A0A2Y9GGP8
uniprot id: A0A2Y9GI38
uniprot id: A0A8M1M476
names: Subcellular Location Annotation
messages: Membrane

29088:SLC25A33
gene id: 29088:SLC25A33
uniprot id: A0A2Y9GIU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:TMEM35A
gene id: 29088:TMEM35A
uniprot id: A0A2Y9HGV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane
messages: Vesicle

29088:LOC110578674
gene id: 29088:LOC110578674
uniprot id: A0A2Y9GXC8
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

29088:VWDE
gene id: 29088:VWDE
uniprot id: A0A2Y9H106
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:GATA2
gene id: 29088:GATA2
uniprot id: A0A2Y9HGC3
uniprot id: A0A2Y9HMN6
names: Subcellular Location Annotation
messages: Nucleus

29088:DNAJA2
gene id: 29088:DNAJA2
uniprot id: A0A2Y9IGE3
uniprot id: A0A8M1MY12
names: Subcellular Location Annotation
messages: Membrane

29088:WASHC5
gene id: 29088:WASHC5
uniprot id: A0A2Y9GYP7
uniprot id: A0A2Y9H5B2
names: Similarity
messages: Belongs to the strumpellin family.

29088:CLDN3
gene id: 29088:CLDN3
uniprot id: A0A2Y9HX56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the claudin family.
messages: Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

29088:VPS37B
gene id: 29088:VPS37B
uniprot id: A0A2Y9HWH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

29088:NDUFS4
gene id: 29088:NDUFS4
uniprot id: A0A2Y9HLI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Mitochondrion inner membrane

29088:LOC110576271
gene id: 29088:LOC110576271
uniprot id: A0A2Y9GPA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldolase class II family. Adducin subfamily.
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.
messages: Cytoplasm
messages: Homotetramer. Interacts with APAF1. May interact with CASP1.

29088:AK1
gene id: 29088:AK1
uniprot id: A0A2Y9H5Q0
uniprot id: A0A8M1MUM2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK1 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

29088:SOGA1
gene id: 29088:SOGA1
uniprot id: A0A2Y9GZU6
names: Similarity
messages: Belongs to the SOGA family.

29088:EYS
gene id: 29088:EYS
uniprot id: A0A2Y9H820
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ANXA2
gene id: 29088:ANXA2
uniprot id: A0A2Y9HCI5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9.
messages: Membrane
messages: basement membrane

29088:MAP6
gene id: 29088:MAP6
uniprot id: A0A2Y9I9G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

29088:GNPTAB
gene id: 29088:GNPTAB
uniprot id: A0A2Y9GVH2
uniprot id: A0A2Y9GVK5
uniprot id: A0A2Y9H1D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the stealth family.
messages: Membrane

29088:NT5C2
gene id: 29088:NT5C2
uniprot id: A0A2Y9HVM2
uniprot id: A0A2Y9HW46
uniprot id: A0A2Y9HW72
uniprot id: A0A2Y9I0W4
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

29088:PSMA8
gene id: 29088:PSMA8
uniprot id: A0A2Y9GRS7
uniprot id: A0A2Y9GRV9
uniprot id: A0A2Y9GVQ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

29088:ACTR8
gene id: 29088:ACTR8
uniprot id: A0A2Y9HGW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

29088:LOC110577293
gene id: 29088:LOC110577293
uniprot id: A0A8M1MDV5
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

29088:DZIP3
gene id: 29088:DZIP3
uniprot id: A0A8M1MP40
names: Subcellular Location Annotation
messages: Cytoplasm

29088:NDUFS5
gene id: 29088:NDUFS5
uniprot id: A0A2Y9GJR0
uniprot id: A0A2Y9GNC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

29088:DHDDS
gene id: 29088:DHDDS
uniprot id: A0A2Y9GJC4
uniprot id: A0A2Y9GPL0
names: Similarity
messages: Belongs to the UPP synthase family.

29088:GPC6
gene id: 29088:GPC6
uniprot id: A0A2Y9HIX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

29088:FER
gene id: 29088:FER
uniprot id: A0A2Y9HZL6
uniprot id: A0A8M1MK39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: Cell membrane
messages: cytoskeleton

29088:FBXO46
gene id: 29088:FBXO46
uniprot id: A0A2Y9GFP3
names: Function
messages: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

29088:CX3CR1
gene id: 29088:CX3CR1
uniprot id: A0A2Y9IC07
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Found in a ternary complex with CX3CL1 and ITGAV:ITGB3 or ITGA4:ITGB1.
messages: Membrane

29088:SEC24D
gene id: 29088:SEC24D
uniprot id: A0A2Y9GLN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

29088:PROX1
gene id: 29088:PROX1
uniprot id: A0A2Y9GGJ4
names: Subcellular Location Annotation
messages: Nucleus

29088:NIPA1
gene id: 29088:NIPA1
uniprot id: A0A2Y9GBF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

29088:LOC110579043
gene id: 29088:LOC110579043
uniprot id: A0A8M1MGU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

29088:HMCN1
gene id: 29088:HMCN1
uniprot id: A0A2Y9GGI7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SMC5
gene id: 29088:SMC5
uniprot id: A0A2Y9HKS2
uniprot id: A0A8M1MVI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Chromosome
messages: Nucleus

29088:XPO4
gene id: 29088:XPO4
uniprot id: A0A8M1M6X1
uniprot id: A0A8M1MAG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Nucleus

29088:CLK2
gene id: 29088:CLK2
uniprot id: A0A2Y9GEU8
uniprot id: A0A2Y9GI55
uniprot id: A0A8M1MEB3
uniprot id: A0A8M1MGG5
uniprot id: A0A8M1MN21
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:SPEG
gene id: 29088:SPEG
uniprot id: A0A2Y9I4Z8
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

29088:TUBB
gene id: 29088:TUBB
uniprot id: A0A2Y9HLQ0
uniprot id: A0A2Y9HLX5
uniprot id: A0A8M1MHN9
uniprot id: A0A8M1MJS1
uniprot id: A0A8M1MRK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

29088:NATD1
gene id: 29088:NATD1
uniprot id: A0A8M1MV56
names: Similarity
messages: Belongs to the NATD1 family.

29088:DUSP29
gene id: 29088:DUSP29
uniprot id: A0A2Y9I0Y4
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

29088:ZFHX3
gene id: 29088:ZFHX3
uniprot id: A0A2Y9IBY2
names: Subcellular Location Annotation
messages: Nucleus

29088:ACSL5
gene id: 29088:ACSL5
uniprot id: A0A2Y9HW61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane

29088:WWOX
gene id: 29088:WWOX
uniprot id: A0A2Y9IBQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm

29088:SWI5
gene id: 29088:SWI5
uniprot id: A0A8M1MR88
names: Function
names: Similarity
messages: Belongs to the SWI5/SAE3 family.
messages: Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination.

29088:LOC110575868
gene id: 29088:LOC110575868
uniprot id: A0A2Y9GTI5
names: Similarity
messages: Belongs to the MS4A family.

29088:LOC110573839
gene id: 29088:LOC110573839
uniprot id: A0A2Y9GL62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

29088:TMA16
gene id: 29088:TMA16
uniprot id: A0A2Y9HYH4
names: Function
names: Similarity
names: Subunit
messages: Associates with pre-60S ribosomal particles.
messages: Belongs to the TMA16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.

29088:LOC110586863
gene id: 29088:LOC110586863
uniprot id: A0A2Y9HMC9
names: Subcellular Location Annotation
messages: Nucleus

29088:TTC19
gene id: 29088:TTC19
uniprot id: A0A8M1MTX9
names: Similarity
messages: Belongs to the TTC19 family.

29088:HSP90AB1
gene id: 29088:HSP90AB1
uniprot id: A0A2Y9H7F4
uniprot id: A0A8M1MLX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 90 family.
messages: Melanosome

29088:RAN
gene id: 29088:RAN
uniprot id: A0A2Y9HQY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

29088:ZDHHC13
gene id: 29088:ZDHHC13
uniprot id: A0A8M1MMS4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

29088:LOC110575114
gene id: 29088:LOC110575114
uniprot id: A0A8M1M950
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

29088:LOC110592863
gene id: 29088:LOC110592863
uniprot id: A0A2Y9GT67
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:LOC110590016
gene id: 29088:LOC110590016
uniprot id: A0A8M1MLG5
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.
messages: Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.

29088:TSPYL1
gene id: 29088:TSPYL1
uniprot id: A0A2Y9HBB3
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

29088:LOC110587219
gene id: 29088:LOC110587219
uniprot id: A0A8M1MMZ9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

29088:POT1
gene id: 29088:POT1
uniprot id: A0A8M1MQ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the telombin family.
messages: Nucleus
messages: telomere

29088:HENMT1
gene id: 29088:HENMT1
uniprot id: A0A8M1M8S4
names: Similarity
messages: Belongs to the methyltransferase superfamily. HEN1 family.

29088:CKS1B
gene id: 29088:CKS1B
uniprot id: A0A2Y9GK60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

29088:ZFHX2
gene id: 29088:ZFHX2
uniprot id: A0A2Y9HHU3
names: Subcellular Location Annotation
messages: Nucleus

29088:SUMO2
gene id: 29088:SUMO2
uniprot id: A0A2Y9GF87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

29088:LOC110574523
gene id: 29088:LOC110574523
uniprot id: A0A2Y9GI94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LHFPL2
gene id: 29088:LHFPL2
uniprot id: A0A2Y9HVM1
names: Subcellular Location Annotation
messages: Membrane

29088:STARD3
gene id: 29088:STARD3
uniprot id: A0A2Y9I793
uniprot id: A0A2Y9IBN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

29088:VARS1
gene id: 29088:VARS1
uniprot id: A0A2Y9HM98
uniprot id: A0A2Y9HME9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

29088:DNAAF6
gene id: 29088:DNAAF6
uniprot id: A0A2Y9G7Y8
names: Similarity
messages: Belongs to the PIH1 family.

29088:PLK1
gene id: 29088:PLK1
uniprot id: A0A8M1MDR2
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:SF1
gene id: 29088:SF1
uniprot id: A0A2Y9GPI6
uniprot id: A0A2Y9GPQ4
uniprot id: A0A2Y9GPV2
uniprot id: A0A2Y9GPV6
uniprot id: A0A2Y9GTL3
uniprot id: A0A2Y9GVB4
uniprot id: A0A8M1MXT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

29088:LOC110583928
gene id: 29088:LOC110583928
uniprot id: A0A2Y9HDD8
uniprot id: A0A2Y9HJM6
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:ZKSCAN2
gene id: 29088:ZKSCAN2
uniprot id: A0A2Y9I3U3
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

29088:LOC110593458
gene id: 29088:LOC110593458
uniprot id: A0A2Y9I912
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:RRN3
gene id: 29088:RRN3
uniprot id: A0A2Y9HQ29
uniprot id: A0A8M1MEL1
names: Similarity
messages: Belongs to the RRN3 family.

29088:IL36G
gene id: 29088:IL36G
uniprot id: A0A2Y9HMU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

29088:TRMT6
gene id: 29088:TRMT6
uniprot id: A0A2Y9GZQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

29088:ELAC2
gene id: 29088:ELAC2
uniprot id: A0A2Y9HFL8
uniprot id: A0A8M1MWS0
uniprot id: A0A8M1MZ88
names: Similarity
messages: Belongs to the RNase Z family.

29088:HABP2
gene id: 29088:HABP2
uniprot id: A0A2Y9HUR1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:CDC5L
gene id: 29088:CDC5L
uniprot id: A0A2Y9H871
uniprot id: A0A2Y9HET4
uniprot id: A0A8M1MKJ4
names: Similarity
messages: Belongs to the CEF1 family.

29088:NT5DC2
gene id: 29088:NT5DC2
uniprot id: A0A2Y9HGH2
uniprot id: A0A8M1MJL2
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

29088:USP30
gene id: 29088:USP30
uniprot id: A0A2Y9I5V8
uniprot id: A0A2Y9ICG6
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

29088:IL2RB
gene id: 29088:IL2RB
uniprot id: A0A2Y9GVP2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Cell membrane
messages: Membrane
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Interacts with SHB upon interleukin stimulation.

29088:OVCH1
gene id: 29088:OVCH1
uniprot id: A0A8M1MBA1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:FURIN
gene id: 29088:FURIN
uniprot id: A0A2Y9GBK8
uniprot id: A0A2Y9GE70
uniprot id: A0A8M1MUB1
names: Similarity
messages: Belongs to the peptidase S8 family.

29088:ST14
gene id: 29088:ST14
uniprot id: A0A2Y9HRE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S1 family.
messages: Degrades extracellular matrix.
messages: Interacts with CDCP1. May interact with TMEFF1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:LOC110589882
gene id: 29088:LOC110589882
uniprot id: A0A2Y9HWZ2
uniprot id: A0A8M1MEY6
uniprot id: A0A8M1MLC1
names: Subcellular Location Annotation
messages: Nucleus

29088:PLXND1
gene id: 29088:PLXND1
uniprot id: A0A2Y9HGT1
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:HOOK1
gene id: 29088:HOOK1
uniprot id: A0A2Y9GC64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

29088:IMPA1
gene id: 29088:IMPA1
uniprot id: A0A2Y9GXW3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

29088:AMELX
gene id: 29088:AMELX
uniprot id: A0A2Y9GKQ5
names: Similarity
messages: Belongs to the amelogenin family.

29088:NSG1
gene id: 29088:NSG1
uniprot id: A0A8M1M524
uniprot id: A0A8M1M5C7
names: Similarity
messages: Belongs to the NSG family.

29088:DIO3
gene id: 29088:DIO3
uniprot id: A0A2Y9G8M7
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

29088:CLP1
gene id: 29088:CLP1
uniprot id: A0A8M1MNJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex, composed of CLP1, TSEN2, TSEN15, TSEN34 and TSEN54. Component of pre-mRNA cleavage complex II (CF-II). Also associates with numerous components of the pre-mRNA cleavage complex I (CF-I/CFIm), including NUDT21, CPSF2, CPSF3, CPSF6 and CPSF7. Interacts with CSTF2 and SYMPK.
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

29088:DTD2
gene id: 29088:DTD2
uniprot id: A0A8M1MTP6
names: Similarity
messages: Belongs to the DTD family.

29088:GSTZ1
gene id: 29088:GSTZ1
uniprot id: A0A2Y9GAY5
uniprot id: A0A2Y9GBX4
uniprot id: A0A8M1MT18
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

29088:ZNF326
gene id: 29088:ZNF326
uniprot id: A0A2Y9H237
uniprot id: A0A2Y9H254
names: Similarity
messages: Belongs to the AKAP95 family.

29088:NANOS1
gene id: 29088:NANOS1
uniprot id: A0A2Y9HVX2
names: Similarity
messages: Belongs to the nanos family.

29088:HMGA1
gene id: 29088:HMGA1
uniprot id: A0A2Y9GM64
uniprot id: A0A2Y9GSV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HMGA family.
messages: Chromosome
messages: HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions.
messages: Interacts with HIPK2.
messages: Nucleus

29088:ARF4
gene id: 29088:ARF4
uniprot id: A0A2Y9HN33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

29088:MED10
gene id: 29088:MED10
uniprot id: A0A2Y9I2L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

29088:AGPAT5
gene id: 29088:AGPAT5
uniprot id: A0A2Y9HJN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Endoplasmic reticulum membrane

29088:MTHFD1L
gene id: 29088:MTHFD1L
uniprot id: A0A2Y9HHB8
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

29088:ANO2
gene id: 29088:ANO2
uniprot id: A0A2Y9H3T0
uniprot id: A0A2Y9H912
uniprot id: A0A8M1MEC2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:TPM2
gene id: 29088:TPM2
uniprot id: A0A2Y9H5D7
uniprot id: A0A2Y9HC37
uniprot id: A0A8M1MSU2
uniprot id: A0A8M1MYF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

29088:ABITRAM
gene id: 29088:ABITRAM
uniprot id: A0A2Y9H6C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABITRAM family.
messages: growth cone
messages: lamellipodium

29088:DKK3
gene id: 29088:DKK3
uniprot id: A0A2Y9GP47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

29088:NCAPG
gene id: 29088:NCAPG
uniprot id: A0A2Y9G870
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

29088:LOC110590979
gene id: 29088:LOC110590979
uniprot id: A0A8M1MI83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

29088:COQ9
gene id: 29088:COQ9
uniprot id: A0A2Y9IFC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

29088:CALR3
gene id: 29088:CALR3
uniprot id: A0A2Y9GIA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

29088:SLC7A4
gene id: 29088:SLC7A4
uniprot id: A0A2Y9H0M7
names: Subcellular Location Annotation
messages: Membrane

29088:TSPAN15
gene id: 29088:TSPAN15
uniprot id: A0A8M1MF25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

29088:RPL39
gene id: 29088:RPL39
uniprot id: A0A2Y9HYY1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

29088:P2RX1
gene id: 29088:P2RX1
uniprot id: A0A2Y9ICD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

29088:TAF2
gene id: 29088:TAF2
uniprot id: A0A8M1MH18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

29088:LOC110573351
gene id: 29088:LOC110573351
uniprot id: A0A2Y9GJ62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:PHB2
gene id: 29088:PHB2
uniprot id: A0A2Y9H3J9
uniprot id: A0A8M1MFN7
uniprot id: A0A8M1MKL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

29088:LOC110593420
gene id: 29088:LOC110593420
uniprot id: A0A8M1MPC6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

29088:SLC25A20
gene id: 29088:SLC25A20
uniprot id: A0A2Y9GU09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:MYT1
gene id: 29088:MYT1
uniprot id: A0A2Y9G313
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

29088:LOC110584754
gene id: 29088:LOC110584754
uniprot id: A0A8M1MIF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:CA13
gene id: 29088:CA13
uniprot id: A0A2Y9H1G8
uniprot id: A0A2Y9H3N2
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

29088:NRM
gene id: 29088:NRM
uniprot id: A0A2Y9HLF8
uniprot id: A0A8M1MH91
uniprot id: A0A8M1MKM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Membrane
messages: Nucleus inner membrane

29088:TIMM13
gene id: 29088:TIMM13
uniprot id: A0A2Y9IAB2
uniprot id: A0A2Y9IER0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

29088:CSTF3
gene id: 29088:CSTF3
uniprot id: A0A2Y9GP12
names: Subcellular Location Annotation
messages: Nucleus

29088:NOP10
gene id: 29088:NOP10
uniprot id: A0A2Y9HHV7
names: Similarity
messages: Belongs to the NOP10 family.

29088:ANXA9
gene id: 29088:ANXA9
uniprot id: A0A2Y9GWY8
uniprot id: A0A2Y9H104
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

29088:LOC110586704
gene id: 29088:LOC110586704
uniprot id: A0A2Y9HLQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sodium/anion cotransporter family.
messages: Membrane

29088:DYNLL2
gene id: 29088:DYNLL2
uniprot id: A0A2Y9I8Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

29088:NALF2
gene id: 29088:NALF2
uniprot id: A0A2Y9G9Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NALF family.
messages: Membrane

29088:RRP7A
gene id: 29088:RRP7A
uniprot id: A0A2Y9GZ94
names: Similarity
messages: Belongs to the RRP7 family.

29088:LOC110583752
gene id: 29088:LOC110583752
uniprot id: A0A8M1MMJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

29088:NHS
gene id: 29088:NHS
uniprot id: A0A2Y9GNG7
uniprot id: A0A8M1M4Y6
names: Similarity
messages: Belongs to the NHS family.

29088:SARDH
gene id: 29088:SARDH
uniprot id: A0A8M1MTG4
names: Similarity
messages: Belongs to the GcvT family.

29088:NKX3-1
gene id: 29088:NKX3-1
uniprot id: A0A2Y9HST2
uniprot id: A0A2Y9HST3
names: Subcellular Location Annotation
messages: Nucleus

29088:ADRB3
gene id: 29088:ADRB3
uniprot id: A0A2Y9GDR8
uniprot id: A0A2Y9GDU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
messages: Cell membrane
messages: Interacts with ARRDC3.
messages: Membrane

29088:CD247
gene id: 29088:CD247
uniprot id: A0A8M1MEV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Membrane

29088:BDKRB1
gene id: 29088:BDKRB1
uniprot id: A0A2Y9GB73
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.

29088:LOC110591181
gene id: 29088:LOC110591181
uniprot id: A0A8M1MK15
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion matrix
messages: Monomer.

29088:GDF15
gene id: 29088:GDF15
uniprot id: A0A2Y9GLE1
names: Similarity
messages: Belongs to the TGF-beta family.

29088:ME3
gene id: 29088:ME3
uniprot id: A0A8M1MRE7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

29088:PFKFB3
gene id: 29088:PFKFB3
uniprot id: A0A2Y9HL73
uniprot id: A0A2Y9HLB0
uniprot id: A0A8M1MKV8
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

29088:LOC110570907
gene id: 29088:LOC110570907
uniprot id: A0A2Y9G6L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SCFD2
gene id: 29088:SCFD2
uniprot id: A0A2Y9I062
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

29088:HSPB2
gene id: 29088:HSPB2
uniprot id: A0A2Y9HK69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Contributes to the transparency and refractive index of the lens. Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
messages: Cytoplasm
messages: Heteromer composed of three CRYAA and one CRYAB subunits. Inter-subunit bridging via zinc ions enhances stability, which is crucial as there is no protein turn over in the lens. Can also form homodimers and homotetramers (dimers of dimers) which serve as the building blocks of homooligomers (By similarity). Within homooligomers, the zinc-binding motif is created from residues of 3 different molecules. His-100 and Glu-102 from one molecule are ligands of the zinc ion, and His-107 and His-154 residues from additional molecules complete the site with tetrahedral coordination geometry (By similarity). Part of a complex required for lens intermediate filament formation composed of BFSP1, BFSP2 and CRYAA.
messages: Nucleus

29088:MMD
gene id: 29088:MMD
uniprot id: A0A2Y9I719
uniprot id: A0A8M1MZ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

29088:EIF3A
gene id: 29088:EIF3A
uniprot id: A0A2Y9HWH9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3L and EIF3K. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with EIF4G1. Also interacts with KRT7 and PIWIL2.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.

29088:PGLS
gene id: 29088:PGLS
uniprot id: A0A2Y9GN90
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

29088:LOC110571740
gene id: 29088:LOC110571740
uniprot id: A0A8M1MMV5
names: Similarity
messages: Belongs to the TMA7 family.

29088:ATP12A
gene id: 29088:ATP12A
uniprot id: A0A2Y9G4A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Membrane

29088:TBX4
gene id: 29088:TBX4
uniprot id: A0A2Y9I7K4
uniprot id: A0A2Y9I7V6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

29088:KCNK17
gene id: 29088:KCNK17
uniprot id: A0A2Y9GM42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

29088:ADAMTS13
gene id: 29088:ADAMTS13
uniprot id: A0A2Y9H6W0
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:CHGB
gene id: 29088:CHGB
uniprot id: A0A2Y9H482
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

29088:EIF4E3
gene id: 29088:EIF4E3
uniprot id: A0A2Y9HMM4
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

29088:TIGD2
gene id: 29088:TIGD2
uniprot id: A0A2Y9I999
names: Subcellular Location Annotation
messages: Nucleus

29088:CFH
gene id: 29088:CFH
uniprot id: A0A8M1MFW7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:CFAP91
gene id: 29088:CFAP91
uniprot id: A0A2Y9HEY0
names: Similarity
messages: Belongs to the CFAP91 family.

29088:FAM118A
gene id: 29088:FAM118A
uniprot id: A0A2Y9GW66
uniprot id: A0A2Y9H0B8
names: Similarity
messages: Belongs to the FAM118 family.

29088:PRPF4B
gene id: 29088:PRPF4B
uniprot id: A0A2Y9HS04
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
messages: Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.

29088:IMPACT
gene id: 29088:IMPACT
uniprot id: A0A2Y9GRS2
uniprot id: A0A2Y9GVP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

29088:LOC110591357
gene id: 29088:LOC110591357
uniprot id: A0A2Y9I2D6
names: Subcellular Location Annotation
messages: Membrane

29088:FCER1G
gene id: 29088:FCER1G
uniprot id: A0A2Y9GJA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Membrane

29088:VPS26A
gene id: 29088:VPS26A
uniprot id: A0A2Y9HUJ0
uniprot id: A0A2Y9HV31
uniprot id: A0A2Y9I1F9
names: Similarity
messages: Belongs to the VPS26 family.

29088:PACC1
gene id: 29088:PACC1
uniprot id: A0A2Y9GGF7
uniprot id: A0A8M1MEL8
uniprot id: A0A8M1MEQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proton-activated chloride channel family.
messages: Cell membrane
messages: Membrane

29088:DDI1
gene id: 29088:DDI1
uniprot id: A0A2Y9HR47
names: Similarity
messages: Belongs to the DDI1 family.

29088:LOC110580224
gene id: 29088:LOC110580224
uniprot id: A0A2Y9H6T8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:ACER2
gene id: 29088:ACER2
uniprot id: A0A8M1MUI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:LSM4
gene id: 29088:LSM4
uniprot id: A0A2Y9GI65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

29088:AP2A2
gene id: 29088:AP2A2
uniprot id: A0A2Y9H865
uniprot id: A0A2Y9H895
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

29088:ACOT13
gene id: 29088:ACOT13
uniprot id: A0A2Y9HM99
names: Similarity
messages: Belongs to the thioesterase PaaI family.

29088:TDP2
gene id: 29088:TDP2
uniprot id: A0A2Y9HLI4
names: Subcellular Location Annotation
messages: PML body

29088:MPP3
gene id: 29088:MPP3
uniprot id: A0A2Y9GH48
uniprot id: A0A8M1MUL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane

29088:CASP14
gene id: 29088:CASP14
uniprot id: A0A2Y9GI75
uniprot id: A0A2Y9GIC9
names: Similarity
messages: Belongs to the peptidase C14A family.

29088:MED24
gene id: 29088:MED24
uniprot id: A0A2Y9I8A2
uniprot id: A0A2Y9ICY4
uniprot id: A0A8M1MVE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 24 family.
messages: Nucleus

29088:LOC110579611
gene id: 29088:LOC110579611
uniprot id: A0A2Y9H051
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

29088:LOC110572688
gene id: 29088:LOC110572688
uniprot id: A0A2Y9GFE6
names: Function
names: Similarity
messages: Belongs to the OPA3 family.
messages: May play some role in mitochondrial processes.

29088:L3MBTL4
gene id: 29088:L3MBTL4
uniprot id: A0A8M1MVE3
names: Subcellular Location Annotation
messages: Nucleus

29088:SLITRK2
gene id: 29088:SLITRK2
uniprot id: A0A2Y9GLS5
names: Similarity
messages: Belongs to the SLITRK family.

29088:LOC110575264
gene id: 29088:LOC110575264
uniprot id: A0A2Y9GRK2
uniprot id: A0A8M1M988
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

29088:AGPS
gene id: 29088:AGPS
uniprot id: A0A2Y9I414
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
messages: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.
messages: Homodimer.
messages: Peroxisome

29088:LOC110581652
gene id: 29088:LOC110581652
uniprot id: A0A2Y9HBX9
names: Subcellular Location Annotation
messages: Nucleus

29088:PDP2
gene id: 29088:PDP2
uniprot id: A0A2Y9I6X5
names: Similarity
messages: Belongs to the PP2C family.

29088:SCNN1B
gene id: 29088:SCNN1B
uniprot id: A0A2Y9GXI4
names: Subcellular Location Annotation
messages: Membrane

29088:NUP50
gene id: 29088:NUP50
uniprot id: A0A2Y9GVY3
uniprot id: A0A2Y9H0B4
names: Subcellular Location Annotation
messages: nuclear pore complex

29088:CDK4
gene id: 29088:CDK4
uniprot id: A0A2Y9GUK3
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:SLC25A1
gene id: 29088:SLC25A1
uniprot id: A0A2Y9H9T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:LOC110575461
gene id: 29088:LOC110575461
uniprot id: A0A8M1M7Q3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Interacts with PPIF; the interaction is impaired by CsA.
messages: Membrane
messages: Mitochondrion inner membrane

29088:ETS2
gene id: 29088:ETS2
uniprot id: A0A2Y9G7H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus
messages: Transcription factor.

29088:ARL8A
gene id: 29088:ARL8A
uniprot id: A0A2Y9GGC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Synapse
messages: spindle

29088:HHIPL2
gene id: 29088:HHIPL2
uniprot id: A0A2Y9HW32
names: Similarity
messages: Belongs to the HHIP family.

29088:AP3M1
gene id: 29088:AP3M1
uniprot id: A0A2Y9HZ37
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

29088:HMGB1
gene id: 29088:HMGB1
uniprot id: A0A2Y9G8C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Cell membrane
messages: Chromosome
messages: Endoplasmic reticulum-Golgi intermediate compartment
messages: Secreted

29088:TNPO1
gene id: 29088:TNPO1
uniprot id: A0A8M1MG68
names: Subcellular Location Annotation
messages: Cytoplasm

29088:GPR37
gene id: 29088:GPR37
uniprot id: A0A2Y9HTZ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:FOXQ1
gene id: 29088:FOXQ1
uniprot id: A0A2Y9HTL4
names: Subcellular Location Annotation
messages: Nucleus

29088:NUDT19
gene id: 29088:NUDT19
uniprot id: A0A2Y9I3E0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

29088:ATXN2L
gene id: 29088:ATXN2L
uniprot id: A0A8M1MCK9
uniprot id: A0A8M1MCL4
uniprot id: A0A8M1MCL9
uniprot id: A0A8M1MCM3
uniprot id: A0A8M1MCM8
uniprot id: A0A8M1MCQ6
uniprot id: A0A8M1MCR1
uniprot id: A0A8M1MCR6
uniprot id: A0A8M1MCS1
uniprot id: A0A8M1MCS6
uniprot id: A0A8M1MET9
uniprot id: A0A8M1MEU4
uniprot id: A0A8M1MEV4
uniprot id: A0A8M1MG75
uniprot id: A0A8M1MG80
uniprot id: A0A8M1MG83
uniprot id: A0A8M1MG88
uniprot id: A0A8M1ML71
uniprot id: A0A8M1ML81
uniprot id: A0A8M1ML86
names: Similarity
messages: Belongs to the ataxin-2 family.

29088:LOC110581031
gene id: 29088:LOC110581031
uniprot id: A0A2Y9H448
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

29088:BCAN
gene id: 29088:BCAN
uniprot id: A0A8M1MDL4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:DNASE1L3
gene id: 29088:DNASE1L3
uniprot id: A0A2Y9HFZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNase I family.
messages: Nucleus envelope
messages: Zymogen granule

29088:ATP5PO
gene id: 29088:ATP5PO
uniprot id: A0A2Y9G3R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

29088:LOC110579989
gene id: 29088:LOC110579989
uniprot id: A0A2Y9H5Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:DUT
gene id: 29088:DUT
uniprot id: A0A2Y9HCQ2
uniprot id: A0A2Y9HD20
uniprot id: A0A2Y9HIW3
uniprot id: A0A2Y9HJC6
uniprot id: A0A8M1MJ36
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

29088:ASIC1
gene id: 29088:ASIC1
uniprot id: A0A2Y9I9B5
names: Subcellular Location Annotation
messages: Membrane

29088:FOXA2
gene id: 29088:FOXA2
uniprot id: A0A2Y9HXJ7
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110576475
gene id: 29088:LOC110576475
uniprot id: A0A2Y9GTZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TCAF1
gene id: 29088:TCAF1
uniprot id: A0A2Y9HFW2
names: Similarity
messages: Belongs to the TCAF family.

29088:FLT3
gene id: 29088:FLT3
uniprot id: A0A2Y9G4X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Membrane

29088:WNT9B
gene id: 29088:WNT9B
uniprot id: A0A2Y9G5B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

29088:AP2A1
gene id: 29088:AP2A1
uniprot id: A0A2Y9GDF7
uniprot id: A0A8M1M383
uniprot id: A0A8M1M8F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

29088:ASPN
gene id: 29088:ASPN
uniprot id: A0A8M1MTR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: extracellular matrix

29088:NAB1
gene id: 29088:NAB1
uniprot id: A0A2Y9I460
uniprot id: A0A2Y9I4R3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

29088:MINDY4B
gene id: 29088:MINDY4B
uniprot id: A0A8M1M1E6
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

29088:DIPK1A
gene id: 29088:DIPK1A
uniprot id: A0A2Y9H7D7
uniprot id: A0A2Y9H909
uniprot id: A0A8M1M9F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

29088:MECP2
gene id: 29088:MECP2
uniprot id: A0A2Y9GIL5
names: Function
names: Subcellular Location Annotation
messages: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
messages: Nucleus

29088:TMEM225
gene id: 29088:TMEM225
uniprot id: A0A2Y9HSC7
names: Subcellular Location Annotation
messages: Membrane

29088:HS6ST2
gene id: 29088:HS6ST2
uniprot id: A0A8M1M1V1
uniprot id: A0A8M1M5L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

29088:LOC110582265
gene id: 29088:LOC110582265
uniprot id: A0A2Y9H8F8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

29088:LOC110575040
gene id: 29088:LOC110575040
uniprot id: A0A8M1M859
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

29088:IGFBP2
gene id: 29088:IGFBP2
uniprot id: A0A2Y9I3Z7
names: Caution
names: Subcellular Location Annotation
names: Subunit
messages: Binds IGF2 more than IGF1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:LRP6
gene id: 29088:LRP6
uniprot id: A0A2Y9H8M5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDLR family.
messages: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes.
messages: Homodimer; disulfide-linked. Forms phosphorylated oligomer aggregates on Wnt-signaling.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:MOGS
gene id: 29088:MOGS
uniprot id: A0A2Y9HY87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

29088:GJB4
gene id: 29088:GJB4
uniprot id: A0A2Y9GPU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

29088:LOC110577050
gene id: 29088:LOC110577050
uniprot id: A0A8M1MV28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.
messages: centrosome

29088:CHRNA5
gene id: 29088:CHRNA5
uniprot id: A0A2Y9GFJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:DUSP1
gene id: 29088:DUSP1
uniprot id: A0A2Y9HXF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

29088:OST4
gene id: 29088:OST4
uniprot id: A0A2Y9HT54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:PUS3
gene id: 29088:PUS3
uniprot id: A0A2Y9HK16
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

29088:KRT12
gene id: 29088:KRT12
uniprot id: A0A2Y9I7E7
names: Similarity
messages: Belongs to the intermediate filament family.

29088:PPP1R12A
gene id: 29088:PPP1R12A
uniprot id: A0A2Y9G5L1
uniprot id: A0A2Y9G610
uniprot id: A0A8M1MFE7
uniprot id: A0A8M1MKA8
names: Subcellular Location Annotation
names: Subunit
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.
messages: stress fiber

29088:BET1L
gene id: 29088:BET1L
uniprot id: A0A8M1MN97
names: Subcellular Location Annotation
messages: Membrane

29088:ARFGEF1
gene id: 29088:ARFGEF1
uniprot id: A0A2Y9H4U7
uniprot id: A0A8M1MDD8
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

29088:TOR3A
gene id: 29088:TOR3A
uniprot id: A0A2Y9GH89
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

29088:LOC110582860
gene id: 29088:LOC110582860
uniprot id: A0A2Y9HA63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:BAIAP2
gene id: 29088:BAIAP2
uniprot id: A0A2Y9GC29
uniprot id: A0A2Y9GC78
uniprot id: A0A2Y9GEY8
uniprot id: A0A2Y9GGI9
uniprot id: A0A8M1MXM3
names: Function
names: Subcellular Location Annotation
messages: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: ruffle

29088:FAM83E
gene id: 29088:FAM83E
uniprot id: A0A2Y9GFV9
names: Similarity
messages: Belongs to the FAM83 family.

29088:DHDH
gene id: 29088:DHDH
uniprot id: A0A2Y9GCX7
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

29088:LOC123324062
gene id: 29088:LOC123324062
uniprot id: A0A8M1M8L2
names: Similarity
messages: Belongs to the PPDPF family.

29088:RPS9
gene id: 29088:RPS9
uniprot id: A0A2Y9GG46
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs.

29088:LGALS3
gene id: 29088:LGALS3
uniprot id: A0A2Y9I4F8
uniprot id: A0A8M1MTD0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Secreted

29088:FERMT1
gene id: 29088:FERMT1
uniprot id: A0A2Y9H005
uniprot id: A0A2Y9H6D7
uniprot id: A0A8M1MVB5
names: Similarity
messages: Belongs to the kindlin family.

29088:RNASEH2B
gene id: 29088:RNASEH2B
uniprot id: A0A2Y9H0L1
uniprot id: A0A2Y9H5E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H2 subunit B family.
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus
messages: The RNase H2 complex is a heterotrimer composed of the catalytic subunit RNASEH2A and the non-catalytic subunits RNASEH2B and RNASEH2C.

29088:GALE
gene id: 29088:GALE
uniprot id: A0A2Y9GKV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.
messages: Homodimer.

29088:ADAM22
gene id: 29088:ADAM22
uniprot id: A0A2Y9H0X5
uniprot id: A0A2Y9H128
uniprot id: A0A2Y9H133
uniprot id: A0A2Y9H138
uniprot id: A0A2Y9H5S0
uniprot id: A0A2Y9H7H6
uniprot id: A0A2Y9H7I0
uniprot id: A0A8M1MQP3
uniprot id: A0A8M1MQP9
uniprot id: A0A8M1MSK1
uniprot id: A0A8M1MSK6
uniprot id: A0A8M1MTY1
uniprot id: A0A8M1MYD1
uniprot id: A0A8M1MYD2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:CNOT11
gene id: 29088:CNOT11
uniprot id: A0A2Y9GAJ1
uniprot id: A0A2Y9GD86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT11 family.
messages: Cytoplasm
messages: Nucleus

29088:LOC110576553
gene id: 29088:LOC110576553
uniprot id: A0A2Y9GQB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SERPINB11
gene id: 29088:SERPINB11
uniprot id: A0A2Y9GXR0
names: Similarity
messages: Belongs to the serpin family.

29088:NBN
gene id: 29088:NBN
uniprot id: A0A8M1M8I6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
messages: Component of the MRN complex.
messages: Nucleus
messages: telomere

29088:ERCC1
gene id: 29088:ERCC1
uniprot id: A0A8M1MVU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

29088:PPP1R9B
gene id: 29088:PPP1R9B
uniprot id: A0A8M1MVF3
uniprot id: A0A8M1MXS2
names: Subcellular Location Annotation
messages: cytoskeleton

29088:ELF1
gene id: 29088:ELF1
uniprot id: A0A2Y9HUM6
uniprot id: A0A2Y9HW64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

29088:RNF10
gene id: 29088:RNF10
uniprot id: A0A2Y9ICZ9
uniprot id: A0A8M1MTF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF10 family.
messages: Cytoplasm

29088:GPRIN3
gene id: 29088:GPRIN3
uniprot id: A0A2Y9I9C9
names: Function
messages: May be involved in neurite outgrowth.

29088:LOC110571764
gene id: 29088:LOC110571764
uniprot id: A0A8M1MMH9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

29088:ALG5
gene id: 29088:ALG5
uniprot id: A0A2Y9G747
uniprot id: A0A8M1MDM6
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

29088:ZSCAN12
gene id: 29088:ZSCAN12
uniprot id: A0A2Y9HSS4
names: Subcellular Location Annotation
messages: Nucleus

29088:UBE2D1
gene id: 29088:UBE2D1
uniprot id: A0A2Y9HUL6
uniprot id: A0A2Y9HZG5
uniprot id: A0A2Y9I0Y5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:NDUFB1
gene id: 29088:NDUFB1
uniprot id: A0A2Y9GD22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:SLC39A14
gene id: 29088:SLC39A14
uniprot id: A0A2Y9HX41
names: Subcellular Location Annotation
messages: Membrane

29088:PNPLA6
gene id: 29088:PNPLA6
uniprot id: A0A2Y9IB10
uniprot id: A0A2Y9IBT8
uniprot id: A0A2Y9IFG8
uniprot id: A0A2Y9IIH7
uniprot id: A0A8M1MLU8
uniprot id: A0A8M1MN65
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:YWHAG
gene id: 29088:YWHAG
uniprot id: A0A2Y9I1X7
names: Similarity
messages: Belongs to the 14-3-3 family.

29088:KRTCAP2
gene id: 29088:KRTCAP2
uniprot id: A0A2Y9GF17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRTCAP2 family.
messages: Membrane

29088:HM13
gene id: 29088:HM13
uniprot id: A0A2Y9H0G8
uniprot id: A0A2Y9H0I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

29088:PPP2R2C
gene id: 29088:PPP2R2C
uniprot id: A0A2Y9G683
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

29088:FABP7
gene id: 29088:FABP7
uniprot id: A0A2Y9HHH6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:SH2B1
gene id: 29088:SH2B1
uniprot id: A0A8M1MAY7
uniprot id: A0A8M1MB67
uniprot id: A0A8M1MD97
uniprot id: A0A8M1MJH2
names: Similarity
messages: Belongs to the SH2B adapter family.

29088:LOC123324586
gene id: 29088:LOC123324586
uniprot id: A0A8M1M317
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:DENND5B
gene id: 29088:DENND5B
uniprot id: A0A2Y9H8Q0
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ARL3
gene id: 29088:ARL3
uniprot id: A0A2Y9HV52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

29088:TMPRSS13
gene id: 29088:TMPRSS13
uniprot id: A0A2Y9HR04
uniprot id: A0A2Y9HRV4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:MTMR6
gene id: 29088:MTMR6
uniprot id: A0A2Y9G8B3
uniprot id: A0A8M1M6L2
uniprot id: A0A8M1M6L7
uniprot id: A0A8M1M6W2
uniprot id: A0A8M1M6W7
uniprot id: A0A8M1M917
uniprot id: A0A8M1MAF5
uniprot id: A0A8M1MAF9
uniprot id: A0A8M1MEU1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

29088:LOC110588369
gene id: 29088:LOC110588369
uniprot id: A0A8M1M435
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

29088:DEFB116
gene id: 29088:DEFB116
uniprot id: A0A2Y9H079
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

29088:MAP3K6
gene id: 29088:MAP3K6
uniprot id: A0A8M1MB49
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

29088:DEFB114
gene id: 29088:DEFB114
uniprot id: A0A2Y9HD19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

29088:PDCD4
gene id: 29088:PDCD4
uniprot id: A0A2Y9I0B2
uniprot id: A0A2Y9I1V3
names: Similarity
messages: Belongs to the PDCD4 family.

29088:NFIB
gene id: 29088:NFIB
uniprot id: A0A2Y9GG52
uniprot id: A0A2Y9GJF4
uniprot id: A0A2Y9GL43
uniprot id: A0A8M1MRE8
uniprot id: A0A8M1MRF9
uniprot id: A0A8M1MTA9
uniprot id: A0A8M1MTB4
uniprot id: A0A8M1MUN6
uniprot id: A0A8M1MYI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

29088:LOC110581765
gene id: 29088:LOC110581765
uniprot id: A0A8M1MTR4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:WT1
gene id: 29088:WT1
uniprot id: A0A2Y9GMD0
uniprot id: A0A2Y9GT30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus speckle

29088:VAMP3
gene id: 29088:VAMP3
uniprot id: A0A2Y9GIT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

29088:LOC123325497
gene id: 29088:LOC123325497
uniprot id: A0A8M1MRE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:RUNX2
gene id: 29088:RUNX2
uniprot id: A0A2Y9H7B2
uniprot id: A0A2Y9H7B8
uniprot id: A0A2Y9H7I7
uniprot id: A0A2Y9HCY2
uniprot id: A0A2Y9HE63
uniprot id: A0A8M1MHH4
names: Function
names: Subcellular Location Annotation
messages: Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
messages: Nucleus

29088:GJA9
gene id: 29088:GJA9
uniprot id: A0A2Y9GKZ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: gap junction

29088:TPM1
gene id: 29088:TPM1
uniprot id: A0A2Y9HCM2
uniprot id: A0A2Y9HCM7
uniprot id: A0A2Y9HCQ8
uniprot id: A0A2Y9HCR3
uniprot id: A0A2Y9HCR7
uniprot id: A0A2Y9HCS2
uniprot id: A0A2Y9HCY0
uniprot id: A0A2Y9HCY5
uniprot id: A0A2Y9HIS4
uniprot id: A0A2Y9HIT0
uniprot id: A0A2Y9HIT7
uniprot id: A0A2Y9HJ87
uniprot id: A0A2Y9HJ92
uniprot id: A0A2Y9HJ97
uniprot id: A0A8M1MJ80
uniprot id: A0A8M1MJ81
uniprot id: A0A8M1MJ85
uniprot id: A0A8M1ML98
uniprot id: A0A8M1MMK3
uniprot id: A0A8M1MT88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

29088:SIDT2
gene id: 29088:SIDT2
uniprot id: A0A2Y9HJU0
uniprot id: A0A2Y9HR69
uniprot id: A0A8M1MPK9
uniprot id: A0A8M1MQW9
uniprot id: A0A8M1MWT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

29088:LOC110589149
gene id: 29088:LOC110589149
uniprot id: A0A8M1MHE5
names: Similarity
messages: Belongs to the SKP1 family.

29088:LOC110592483
gene id: 29088:LOC110592483
uniprot id: A0A2Y9H1V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

29088:PPP4R2
gene id: 29088:PPP4R2
uniprot id: A0A2Y9HFQ5
uniprot id: A0A8M1MIW7
uniprot id: A0A8M1MP76
names: Similarity
messages: Belongs to the PPP4R2 family.

29088:CHPF
gene id: 29088:CHPF
uniprot id: A0A2Y9I8C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

29088:KHDC3L
gene id: 29088:KHDC3L
uniprot id: A0A8M1MKH4
names: Similarity
messages: Belongs to the KHDC1 family.

29088:GCH1
gene id: 29088:GCH1
uniprot id: A0A2Y9HZW5
uniprot id: A0A2Y9I6A3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

29088:CD163
gene id: 29088:CD163
uniprot id: A0A8M1MAH4
uniprot id: A0A8M1MAQ6
uniprot id: A0A8M1MCU2
uniprot id: A0A8M1MJ04
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ING1
gene id: 29088:ING1
uniprot id: A0A2Y9HPQ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

29088:LOC110590414
gene id: 29088:LOC110590414
uniprot id: A0A8M1MM78
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

29088:DIO1
gene id: 29088:DIO1
uniprot id: A0A2Y9GKC0
uniprot id: A0A2Y9GQK4
uniprot id: A0A8M1MBQ2
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

29088:CRY2
gene id: 29088:CRY2
uniprot id: A0A2Y9GP60
uniprot id: A0A2Y9GT98
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

29088:VPS45
gene id: 29088:VPS45
uniprot id: A0A2Y9GWN4
uniprot id: A0A8M1M881
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

29088:HAP1
gene id: 29088:HAP1
uniprot id: A0A8M1MZ89
names: Subcellular Location Annotation
messages: Early endosome
messages: Mitochondrion

29088:SLC35B1
gene id: 29088:SLC35B1
uniprot id: A0A2Y9I6Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

29088:ERCC4
gene id: 29088:ERCC4
uniprot id: A0A2Y9HQ83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

29088:TCEANC2
gene id: 29088:TCEANC2
uniprot id: A0A2Y9GQL6
names: Subcellular Location Annotation
messages: Nucleus

29088:HESX1
gene id: 29088:HESX1
uniprot id: A0A2Y9HMQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANF homeobox family.
messages: Nucleus

29088:LECT2
gene id: 29088:LECT2
uniprot id: A0A2Y9I1J7
names: Similarity
messages: Belongs to the LECT2/MIM-1 family.

29088:CTSF
gene id: 29088:CTSF
uniprot id: A0A8M1MR04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

29088:TSPOAP1
gene id: 29088:TSPOAP1
uniprot id: A0A8M1MX50
names: Similarity
messages: Belongs to the RIMBP family.

29088:PLXNA4
gene id: 29088:PLXNA4
uniprot id: A0A2Y9H9W0
uniprot id: A0A2Y9H9X6
uniprot id: A0A2Y9HGH4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:NUPR1
gene id: 29088:NUPR1
uniprot id: A0A2Y9HW58
names: Similarity
messages: Belongs to the NUPR family.

29088:NFASC
gene id: 29088:NFASC
uniprot id: A0A2Y9GSJ7
uniprot id: A0A2Y9GSV4
uniprot id: A0A2Y9GWR4
uniprot id: A0A8M1MI08
uniprot id: A0A8M1MN84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

29088:BAZ2B
gene id: 29088:BAZ2B
uniprot id: A0A2Y9I527
uniprot id: A0A2Y9I580
uniprot id: A0A2Y9I9X6
uniprot id: A0A2Y9ICD9
names: Similarity
messages: Belongs to the WAL family.

29088:EXOC6
gene id: 29088:EXOC6
uniprot id: A0A2Y9I115
uniprot id: A0A8M1MF58
uniprot id: A0A8M1MF88
uniprot id: A0A8M1MHA4
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

29088:PIAS3
gene id: 29088:PIAS3
uniprot id: A0A2Y9GWW1
names: Similarity
messages: Belongs to the PIAS family.

29088:SART3
gene id: 29088:SART3
uniprot id: A0A2Y9I547
names: Subcellular Location Annotation
messages: nucleoplasm

29088:EIF3J
gene id: 29088:EIF3J
uniprot id: A0A2Y9HNN8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl (A) site. It may regulate the interaction between the 43S PIC and mRNA.
messages: Cytoplasm
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.

29088:STK32C
gene id: 29088:STK32C
uniprot id: A0A2Y9IAZ0
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:LOC110576547
gene id: 29088:LOC110576547
uniprot id: A0A2Y9GQ38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SERP1
gene id: 29088:SERP1
uniprot id: A0A2Y9GUX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

29088:POLR1A
gene id: 29088:POLR1A
uniprot id: A0A2Y9HU90
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

29088:NIPAL3
gene id: 29088:NIPAL3
uniprot id: A0A2Y9GJ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

29088:MIA2
gene id: 29088:MIA2
uniprot id: A0A2Y9HZR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Plays a role in the regulation of neuronal activity.
messages: Rough endoplasmic reticulum membrane

29088:STXBP1
gene id: 29088:STXBP1
uniprot id: A0A2Y9HB09
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

29088:LOC110588997
gene id: 29088:LOC110588997
uniprot id: A0A2Y9HTH3
uniprot id: A0A2Y9HYW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the leptin family.
messages: Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal metabolism, influences reproductive function, regulates pancreatic beta-cell function and insulin secretion, is pro-angiogenic for endothelial cell and affects innate and adaptive immunity. In the arcuate nucleus of the hypothalamus, activates by depolarization POMC neurons inducing FOS and SOCS3 expression to release anorexigenic peptides and inhibits by hyperpolarization NPY neurons inducing SOCS3 with a consequent reduction on release of orexigenic peptides. In addition to its known satiety inducing effect, has a modulatory role in nutrient absorption. In the intestine, reduces glucose absorption by enterocytes by activating PKC and leading to a sequential activation of p38, PI3K and ERK signaling pathways which exerts an inhibitory effect on glucose absorption. Acts as a growth factor on certain tissues, through the activation of different signaling pathways increases expression of genes involved in cell cycle regulation such as CCND1, via JAK2-STAT3 pathway, or VEGFA, via MAPK1/3 and PI3K-AKT1 pathways. May also play an apoptotic role via JAK2-STAT3 pathway and up-regulation of BIRC5 expression. Pro-angiogenic, has mitogenic activity on vascular endothelial cells and plays a role in matrix remodeling by regulating the expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs). In innate immunity, modulates the activity and function of neutrophils by in…
messages: Secreted

29088:TDP1
gene id: 29088:TDP1
uniprot id: A0A8M1MMY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

29088:PPM1D
gene id: 29088:PPM1D
uniprot id: A0A2Y9IBS7
names: Similarity
messages: Belongs to the PP2C family.

29088:GABRA1
gene id: 29088:GABRA1
uniprot id: A0A2Y9HWG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:LOC110574960
gene id: 29088:LOC110574960
uniprot id: A0A2Y9GJW0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MELK
gene id: 29088:MELK
uniprot id: A0A2Y9HCR1
uniprot id: A0A8M1MRB9
uniprot id: A0A8M1MRD0
uniprot id: A0A8M1MT82
uniprot id: A0A8M1MUK3
uniprot id: A0A8M1MUK8
uniprot id: A0A8M1MYH7
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

29088:PGS1
gene id: 29088:PGS1
uniprot id: A0A2Y9GC47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

29088:FZD10
gene id: 29088:FZD10
uniprot id: A0A2Y9HWR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Membrane

29088:TGFB1
gene id: 29088:TGFB1
uniprot id: A0A2Y9HY24
uniprot id: A0A8M1MXX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Required to maintain the Transforming growth factor beta-1 (TGF-beta-1) chain in a latent state during storage in extracellular matrix. Associates non-covalently with TGF-beta-1 and regulates its activation via interaction with 'milieu molecules', such as LTBP1, LRRC32/GARP and LRRC33/NRROS, that control activation of TGF-beta-1. Interaction with LRRC33/NRROS regulates activation of TGF-beta-1 in macrophages and microglia. Interaction with LRRC32/GARP controls activation of TGF-beta-1 on the surface of activated regulatory T-cells (Tregs). Interaction with integrins (ITGAV:ITGB6 or ITGAV:ITGB8) results in distortion of the Latency-associated peptide chain and subsequent release of the active TGF-beta-1.
messages: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
messages: extracellular matrix

29088:LIPA
gene id: 29088:LIPA
uniprot id: A0A2Y9HQM8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

29088:INPP5D
gene id: 29088:INPP5D
uniprot id: A0A8M1MA34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane

29088:LOC110590652
gene id: 29088:LOC110590652
uniprot id: A0A2Y9I010
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

29088:MALSU1
gene id: 29088:MALSU1
uniprot id: A0A2Y9H1F4
names: Similarity
messages: Belongs to the Iojap/RsfS family.

29088:NPY
gene id: 29088:NPY
uniprot id: A0A2Y9H686
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

29088:CUEDC2
gene id: 29088:CUEDC2
uniprot id: A0A2Y9HV73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUEDC2 family.
messages: Cytoplasm
messages: Nucleus

29088:KCNH4
gene id: 29088:KCNH4
uniprot id: A0A2Y9GE84
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

29088:GPR135
gene id: 29088:GPR135
uniprot id: A0A2Y9I4R1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:SPATA20
gene id: 29088:SPATA20
uniprot id: A0A2Y9I7B6
names: Function
names: Subcellular Location Annotation
messages: May play a role in fertility regulation.
messages: Secreted

29088:LOC110589396
gene id: 29088:LOC110589396
uniprot id: A0A8M1MGB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNW family.
messages: Identified in the spliceosome C complex.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

29088:LOC110585328
gene id: 29088:LOC110585328
uniprot id: A0A8M1MTU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: centrosome
messages: spindle pole

29088:LOC110577191
gene id: 29088:LOC110577191
uniprot id: A0A2Y9GSC4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

29088:LPCAT4
gene id: 29088:LPCAT4
uniprot id: A0A2Y9HH43
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

29088:LOC110574035
gene id: 29088:LOC110574035
uniprot id: A0A8M1M5S1
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

29088:LOC110590018
gene id: 29088:LOC110590018
uniprot id: A0A8M1MLR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

29088:FXYD1
gene id: 29088:FXYD1
uniprot id: A0A2Y9I4U9
uniprot id: A0A8M1MZH9
names: Similarity
messages: Belongs to the FXYD family.

29088:LOC110586583
gene id: 29088:LOC110586583
uniprot id: A0A8M1MGG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

29088:TRPC5
gene id: 29088:TRPC5
uniprot id: A0A8M1M403
names: Subcellular Location Annotation
messages: Membrane

29088:LOC123324066
gene id: 29088:LOC123324066
uniprot id: A0A8M1M5G7
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

29088:CHPT1
gene id: 29088:CHPT1
uniprot id: A0A2Y9GZM0
uniprot id: A0A2Y9H1C5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

29088:LOC110583104
gene id: 29088:LOC110583104
uniprot id: A0A8M1MHE1
uniprot id: A0A8M1MJH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b5 family.
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Endoplasmic reticulum

29088:PHF10
gene id: 29088:PHF10
uniprot id: A0A2Y9HCJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAYP family.
messages: Nucleus

29088:LOC110581735
gene id: 29088:LOC110581735
uniprot id: A0A2Y9H6L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

29088:SLC47A2
gene id: 29088:SLC47A2
uniprot id: A0A8M1MXM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

29088:FZD3
gene id: 29088:FZD3
uniprot id: A0A2Y9HSI3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:LOC110578560
gene id: 29088:LOC110578560
uniprot id: A0A2Y9GX01
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system.

29088:TOR1A
gene id: 29088:TOR1A
uniprot id: A0A2Y9H6S7
uniprot id: A0A2Y9H6Y3
uniprot id: A0A2Y9HCD2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum lumen
messages: Homohexamer. Interacts with TOR1B; the interaction may be specific of neural tissues. Interacts (ATP-bound) with TOR1AIP1 and TOR1AIP2; the interactions induce ATPase activity. Interacts with KLHL14; preferentially when ATP-free. Interacts with KLC1 (via TPR repeats); the interaction associates TOR1A with the kinesin oligomeric complex. Interacts with COPS4; the interaction associates TOR1A with the CSN complex. Interacts with SNAPIN; the interaction is direct and associates SNAPIN with the CSN complex. Interacts with STON2. Interacts (ATP-bound) with SYNE3 (via KASH domain); the interaction is required for SYNE3 nuclear envelope localization. Interacts with VIM; the interaction associates TOR1A with the cytoskeleton. Interacts with PLEC. Interacts (ATP-bound) with SLC6A3; regulates SLC6A3 transport to the plasma membrane.
messages: Membrane
messages: growth cone

29088:YIPF1
gene id: 29088:YIPF1
uniprot id: A0A2Y9GKH7
uniprot id: A0A2Y9GQJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

29088:HOXC9
gene id: 29088:HOXC9
uniprot id: A0A2Y9GTB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

29088:ARL5A
gene id: 29088:ARL5A
uniprot id: A0A2Y9I3B4
uniprot id: A0A2Y9I3K0
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

29088:LOC110570075
gene id: 29088:LOC110570075
uniprot id: A0A8M1MEF4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Monomer.

29088:LOC110569607
gene id: 29088:LOC110569607
uniprot id: A0A8M1M138
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:SKA3
gene id: 29088:SKA3
uniprot id: A0A2Y9G7W6
uniprot id: A0A8M1MDQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA3 family.
messages: kinetochore
messages: spindle

29088:DPF1
gene id: 29088:DPF1
uniprot id: A0A2Y9HYD6
uniprot id: A0A2Y9HYI3
uniprot id: A0A2Y9I565
uniprot id: A0A8M1MXG8
names: Similarity
messages: Belongs to the requiem/DPF family.

29088:SH2B3
gene id: 29088:SH2B3
uniprot id: A0A2Y9HRC8
names: Similarity
messages: Belongs to the SH2B adapter family.

29088:FEZ1
gene id: 29088:FEZ1
uniprot id: A0A2Y9HJW5
uniprot id: A0A2Y9HRI8
names: Similarity
messages: Belongs to the zygin family.

29088:OVCH2
gene id: 29088:OVCH2
uniprot id: A0A2Y9GQ72
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ATP11C
gene id: 29088:ATP11C
uniprot id: A0A2Y9GMA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

29088:APH1B
gene id: 29088:APH1B
uniprot id: A0A2Y9HCZ1
uniprot id: A0A2Y9HDC0
uniprot id: A0A2Y9HJ63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

29088:LOC110591816
gene id: 29088:LOC110591816
uniprot id: A0A8M1M7B5
uniprot id: A0A8M1MAV7
names: Similarity
messages: Belongs to the NAC-beta family.

29088:S1PR3
gene id: 29088:S1PR3
uniprot id: A0A2Y9HE72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

29088:HIF1A
gene id: 29088:HIF1A
uniprot id: A0A2Y9I6M7
uniprot id: A0A8M1MNW5
names: Subcellular Location Annotation
messages: Cytoplasm

29088:IRF7
gene id: 29088:IRF7
uniprot id: A0A2Y9HDQ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

29088:LYRM1
gene id: 29088:LYRM1
uniprot id: A0A2Y9HF19
uniprot id: A0A8M1MJG2
names: Similarity
messages: Belongs to the complex I LYR family.

29088:NOXRED1
gene id: 29088:NOXRED1
uniprot id: A0A2Y9G8L2
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

29088:GALNT18
gene id: 29088:GALNT18
uniprot id: A0A2Y9GNX4
uniprot id: A0A8M1MPK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:SLC24A5
gene id: 29088:SLC24A5
uniprot id: A0A2Y9HD64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

29088:NAPA
gene id: 29088:NAPA
uniprot id: A0A2Y9GCY5
uniprot id: A0A8M1MVU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

29088:PRIM2
gene id: 29088:PRIM2
uniprot id: A0A2Y9H7H4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.

29088:TPPP2
gene id: 29088:TPPP2
uniprot id: A0A2Y9HHU5
names: Similarity
messages: Belongs to the TPPP family.

29088:GRPR
gene id: 29088:GRPR
uniprot id: A0A2Y9GEM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:CHMP7
gene id: 29088:CHMP7
uniprot id: A0A2Y9HS97
uniprot id: A0A8M1M3P7
names: Similarity
messages: Belongs to the SNF7 family.

29088:KCNS2
gene id: 29088:KCNS2
uniprot id: A0A2Y9GYP1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:PKIG
gene id: 29088:PKIG
uniprot id: A0A2Y9GZB1
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

29088:GPR39
gene id: 29088:GPR39
uniprot id: A0A2Y9HIT6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:MBTD1
gene id: 29088:MBTD1
uniprot id: A0A2Y9I865
uniprot id: A0A2Y9I8F6
uniprot id: A0A2Y9I8Y0
uniprot id: A0A2Y9ICV3
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110576116
gene id: 29088:LOC110576116
uniprot id: A0A2Y9GUE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LAMA4
gene id: 29088:LAMA4
uniprot id: A0A8M1MKJ9
uniprot id: A0A8M1MSH3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:PMM2
gene id: 29088:PMM2
uniprot id: A0A2Y9HWP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

29088:CAPN5
gene id: 29088:CAPN5
uniprot id: A0A2Y9IG15
names: Similarity
messages: Belongs to the peptidase C2 family.

29088:DDOST
gene id: 29088:DDOST
uniprot id: A0A2Y9GKN7
uniprot id: A0A2Y9GKY5
uniprot id: A0A2Y9GR22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

29088:CDCP2
gene id: 29088:CDCP2
uniprot id: A0A8M1MAC3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:STAC2
gene id: 29088:STAC2
uniprot id: A0A2Y9I7U7
names: Subcellular Location Annotation
messages: sarcolemma

29088:IRF5
gene id: 29088:IRF5
uniprot id: A0A2Y9HTV0
uniprot id: A0A2Y9HYP2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

29088:MEOX2
gene id: 29088:MEOX2
uniprot id: A0A2Y9H1D7
names: Subcellular Location Annotation
messages: Nucleus

29088:GRIA4
gene id: 29088:GRIA4
uniprot id: A0A2Y9HKF9
uniprot id: A0A2Y9HKR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

29088:ADAMTS4
gene id: 29088:ADAMTS4
uniprot id: A0A2Y9GES2
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:SSR4
gene id: 29088:SSR4
uniprot id: A0A2Y9GIY0
uniprot id: A0A2Y9GNX0
uniprot id: A0A8M1M5A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-delta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

29088:LOC110575851
gene id: 29088:LOC110575851
uniprot id: A0A2Y9GRU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ULK3
gene id: 29088:ULK3
uniprot id: A0A2Y9HJ45
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:GREM2
gene id: 29088:GREM2
uniprot id: A0A2Y9GK44
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:SFRP5
gene id: 29088:SFRP5
uniprot id: A0A2Y9HV68
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110591473
gene id: 29088:LOC110591473
uniprot id: A0A2Y9I281
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

29088:TMEM176B
gene id: 29088:TMEM176B
uniprot id: A0A2Y9HG59
names: Similarity
messages: Belongs to the TMEM176 family.

29088:CAMSAP2
gene id: 29088:CAMSAP2
uniprot id: A0A2Y9GGX2
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

29088:ACYP2
gene id: 29088:ACYP2
uniprot id: A0A2Y9I3U4
uniprot id: A0A8M1MNG7
names: Caution
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:TGM2
gene id: 29088:TGM2
uniprot id: A0A2Y9GZI9
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

29088:TSPYL5
gene id: 29088:TSPYL5
uniprot id: A0A2Y9GYJ0
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

29088:ARPC5L
gene id: 29088:ARPC5L
uniprot id: A0A2Y9H724
uniprot id: A0A8M1MSD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.
messages: May be a component of the Arp2/3 complex in which it may replace ARPC5.
messages: May function as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

29088:PSMD1
gene id: 29088:PSMD1
uniprot id: A0A2Y9H9T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S1 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

29088:RPL27
gene id: 29088:RPL27
uniprot id: A0A2Y9HDU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

29088:STK40
gene id: 29088:STK40
uniprot id: A0A2Y9GKZ3
uniprot id: A0A2Y9GL34
uniprot id: A0A2Y9GLA0
uniprot id: A0A8M1M9G0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
messages: Nucleus

29088:SFRP2
gene id: 29088:SFRP2
uniprot id: A0A2Y9HSB3
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110594174
gene id: 29088:LOC110594174
uniprot id: A0A2Y9IBE8
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Homotetramer.

29088:ZNF500
gene id: 29088:ZNF500
uniprot id: A0A8M1MJY9
names: Subcellular Location Annotation
messages: Nucleus

29088:TMEM200B
gene id: 29088:TMEM200B
uniprot id: A0A2Y9GL63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

29088:DYSF
gene id: 29088:DYSF
uniprot id: A0A2Y9HSL6
uniprot id: A0A2Y9HSM2
uniprot id: A0A2Y9HSM7
uniprot id: A0A2Y9HT29
uniprot id: A0A2Y9HT38
uniprot id: A0A2Y9HT40
uniprot id: A0A2Y9HT45
uniprot id: A0A2Y9HT51
uniprot id: A0A2Y9HXZ9
uniprot id: A0A2Y9HY04
uniprot id: A0A2Y9HY08
uniprot id: A0A2Y9HZH6
uniprot id: A0A2Y9HZI3
uniprot id: A0A2Y9HZJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferlin family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

29088:MYADM
gene id: 29088:MYADM
uniprot id: A0A2Y9GFR7
names: Subcellular Location Annotation
messages: Membrane

29088:CUL4B
gene id: 29088:CUL4B
uniprot id: A0A2Y9GR38
uniprot id: A0A8M1M4A8
uniprot id: A0A8M1M9M4
names: Similarity
messages: Belongs to the cullin family.

29088:LETMD1
gene id: 29088:LETMD1
uniprot id: A0A8M1MBX3
uniprot id: A0A8M1MBX8
uniprot id: A0A8M1MC22
uniprot id: A0A8M1MC28
uniprot id: A0A8M1ME55
uniprot id: A0A8M1ME59
uniprot id: A0A8M1MFJ4
uniprot id: A0A8M1MFJ8
uniprot id: A0A8M1MKF7
uniprot id: A0A8M1MKG3
uniprot id: A0A8M1MKG8
names: Subcellular Location Annotation
messages: Membrane

29088:CHD1
gene id: 29088:CHD1
uniprot id: A0A8M1MFH1
names: Subcellular Location Annotation
messages: Nucleus

29088:RAD23A
gene id: 29088:RAD23A
uniprot id: A0A2Y9I9P9
uniprot id: A0A2Y9IAD5
uniprot id: A0A8M1MIT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

29088:NDUFB7
gene id: 29088:NDUFB7
uniprot id: A0A2Y9IHD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

29088:ANKS6
gene id: 29088:ANKS6
uniprot id: A0A2Y9H6K2
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

29088:CUL1
gene id: 29088:CUL1
uniprot id: A0A2Y9HAC5
uniprot id: A0A2Y9HH41
names: Similarity
messages: Belongs to the cullin family.

29088:LOC110586427
gene id: 29088:LOC110586427
uniprot id: A0A2Y9HKU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110592261
gene id: 29088:LOC110592261
uniprot id: A0A2Y9IBW5
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

29088:AIMP2
gene id: 29088:AIMP2
uniprot id: A0A2Y9GA08
uniprot id: A0A2Y9GDP8
uniprot id: A0A8M1MBD7
uniprot id: A0A8M1MEV5
uniprot id: A0A8M1MJQ0
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol

29088:OLFM1
gene id: 29088:OLFM1
uniprot id: A0A2Y9H5E3
uniprot id: A0A8M1MR19
uniprot id: A0A8M1MR29
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

29088:ANKRD13A
gene id: 29088:ANKRD13A
uniprot id: A0A2Y9I594
uniprot id: A0A2Y9I5F7
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

29088:JUNB
gene id: 29088:JUNB
uniprot id: A0A2Y9IEM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

29088:CBS
gene id: 29088:CBS
uniprot id: A0A2Y9G714
uniprot id: A0A2Y9G9H5
uniprot id: A0A2Y9GAL5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

29088:LOC110572549
gene id: 29088:LOC110572549
uniprot id: A0A2Y9GBZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:KCNK2
gene id: 29088:KCNK2
uniprot id: A0A2Y9GGG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

29088:SLC10A3
gene id: 29088:SLC10A3
uniprot id: A0A2Y9HBW4
uniprot id: A0A2Y9HIJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

29088:TYR
gene id: 29088:TYR
uniprot id: A0A2Y9G6W8
uniprot id: A0A8M1MQI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

29088:TECPR1
gene id: 29088:TECPR1
uniprot id: A0A2Y9GCI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TECPR1 family.
messages: Lysosome membrane
messages: autophagosome membrane

29088:STX1A
gene id: 29088:STX1A
uniprot id: A0A8M1MER9
uniprot id: A0A8M1MJL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

29088:XKR8
gene id: 29088:XKR8
uniprot id: A0A2Y9GJL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

29088:IGFBP5
gene id: 29088:IGFBP5
uniprot id: A0A2Y9I479
names: Caution
names: Function
names: Subcellular Location Annotation
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:LOC110580601
gene id: 29088:LOC110580601
uniprot id: A0A2Y9H2V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:FAM32A
gene id: 29088:FAM32A
uniprot id: A0A2Y9GLJ0
names: Similarity
messages: Belongs to the FAM32 family.

29088:NKAIN2
gene id: 29088:NKAIN2
uniprot id: A0A2Y9HB00
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:PHF1
gene id: 29088:PHF1
uniprot id: A0A2Y9GM36
uniprot id: A0A2Y9GM89
uniprot id: A0A2Y9GQX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

29088:ALK
gene id: 29088:ALK
uniprot id: A0A8M1MLN6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.

29088:LBR
gene id: 29088:LBR
uniprot id: A0A2Y9GAJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus inner membrane

29088:PENK
gene id: 29088:PENK
uniprot id: A0A2Y9GXZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Neuropeptide that competes with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Secreted
messages: chromaffin granule lumen

29088:RECQL5
gene id: 29088:RECQL5
uniprot id: A0A2Y9GF78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

29088:LCK
gene id: 29088:LCK
uniprot id: A0A2Y9GN32
uniprot id: A0A2Y9GPR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

29088:LOC110581192
gene id: 29088:LOC110581192
uniprot id: A0A2Y9HA45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:CCDC167
gene id: 29088:CCDC167
uniprot id: A0A2Y9GMA4
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110583041
gene id: 29088:LOC110583041
uniprot id: A0A8M1MHA9
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

29088:LGI4
gene id: 29088:LGI4
uniprot id: A0A8M1MZI5
names: Subcellular Location Annotation
messages: Secreted

29088:RARS1
gene id: 29088:RARS1
uniprot id: A0A2Y9HV47
uniprot id: A0A2Y9HV55
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

29088:PODXL2
gene id: 29088:PODXL2
uniprot id: A0A2Y9HH24
names: Subcellular Location Annotation
messages: Membrane

29088:BANF1
gene id: 29088:BANF1
uniprot id: A0A2Y9GPY7
names: Subcellular Location Annotation
messages: Nucleus

29088:HEPH
gene id: 29088:HEPH
uniprot id: A0A2Y9GD49
uniprot id: A0A8M1M1H7
uniprot id: A0A8M1M3Q4
uniprot id: A0A8M1M591
uniprot id: A0A8M1M903
names: Similarity
messages: Belongs to the multicopper oxidase family.

29088:LOC110592628
gene id: 29088:LOC110592628
uniprot id: A0A8M1MQL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

29088:RNF8
gene id: 29088:RNF8
uniprot id: A0A2Y9GMA1
uniprot id: A0A2Y9GT02
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: According to a well-established model, RNF8 initiate H2A 'Lys-63'-linked ubiquitination leading to recruitment of RNF168 to amplify H2A 'Lys-63'-linked ubiquitination. However, other data suggest that RNF168 is the priming ubiquitin ligase by mediating monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub respectively). These data suggest that RNF168 might be recruited to DSBs sites in a RNF8-dependent manner by binding to non-histone proteins ubiquitinated via 'Lys-63'-linked and initiates monoubiquitination of H2A, which is then amplified by RNF8. Additional evidences are however required to confirm these data.
messages: Autoubiquitinated through 'Lys-48' and 'Lys-63' of ubiquitin. 'Lys-63' polyubiquitination is mediated by UBE2N. 'Lys-29'-type polyubiquitination is also observed, but it doesn't require its own functional RING-type zinc finger.
messages: Belongs to the CHFR family.
messages: Belongs to the RNF8 family.
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53BP1 and BRCA1 ionizing radiation-induced foci (IRIF). Also controls the recruitment of UIMC1-BRCC3 (RAP80-BRCC36) and PAXIP1/PTIP to DNA damage sites. Also recruited at DNA interstrand cross-links (ICLs) sites and catalyzes 'Lys-63'-linked ubiquitination of histones H2A and H2AX, leading to recruitment of FAAP20 and Fanconi anemia (FA) complex, followed by interstrand cross-link repair. H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Promotes the formation of 'Lys-63'-linked polyubiquitin chains via interactions with the specific ubiquitin-conjugating UBE2N/UBC13 and ubiquitinates non-histone substrates such as PCNA. Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation. Also catalyzes the formation of 'Lys-48'-linked polyubiquitin chains via interaction with the ubiquitin-conjugating UBE2L6/UBCH8, leading to degradation of substrate proteins such as CHEK2, JMJD2A/KDM4A and KU80/XRCC5: it is still unclear how the preference toward 'Lys-48'- versus 'Lys-63'-linked ubiquitination is regulated but it could be due to RNF8 ability to interact with specific E2 specific ligases. For instance, interaction with phosphorylated HERC2 promotes the association between RNF8 and UBE2N/UBC13 and favors the specific formation of 'Lys-63'-linked ubiquitin chains…
messages: Homodimer. Forms a E2-E3 ubiquitin ligase complex composed of the RNF8 homodimer and a E2 heterodimer of UBE2N and UBE2V2. Interacts with class III E2s, including UBE2E1, UBE2E2, and UBE2E3 and with UBE2N. Interacts with RXRA. Interacts (via FHA domain) with phosphorylated HERC2 (via C-terminus). Interacts with PIWIL1; leading to sequester RNF8 in the cytoplasm.
messages: Midbody
messages: Nucleus
messages: The FHA domain specifically recognizes and binds ATM-phosphorylated MDC1 and phosphorylated HERC2.
messages: telomere

29088:MRPL22
gene id: 29088:MRPL22
uniprot id: A0A2Y9HML5
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

29088:ERBB2
gene id: 29088:ERBB2
uniprot id: A0A2Y9I878
uniprot id: A0A8M1MUF1
uniprot id: A0A8M1MUF6
uniprot id: A0A8M1MUF7
uniprot id: A0A8M1MUF9
uniprot id: A0A8M1MUG4
uniprot id: A0A8M1MUG7
uniprot id: A0A8M1MUG9
uniprot id: A0A8M1MW88
uniprot id: A0A8M1MW93
uniprot id: A0A8M1MW98
uniprot id: A0A8M1MWA4
uniprot id: A0A8M1MX75
uniprot id: A0A8M1MX78
uniprot id: A0A8M1MX81
uniprot id: A0A8M1MX83
uniprot id: A0A8M1MZ43
uniprot id: A0A8M1MZ44
uniprot id: A0A8M1MZ45
uniprot id: A0A8M1MZ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

29088:PCYT1A
gene id: 29088:PCYT1A
uniprot id: A0A2Y9HE48
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

29088:GRPEL2
gene id: 29088:GRPEL2
uniprot id: A0A2Y9HLQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

29088:LOC110573963
gene id: 29088:LOC110573963
uniprot id: A0A8M1MNF9
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.
messages: Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.

29088:LOC110569723
gene id: 29088:LOC110569723
uniprot id: A0A2Y9G6C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:IPO4
gene id: 29088:IPO4
uniprot id: A0A2Y9HPD3
names: Subcellular Location Annotation
messages: Cytoplasm

29088:VHL
gene id: 29088:VHL
uniprot id: A0A2Y9HFW0
uniprot id: A0A8M1MH11
names: Similarity
messages: Belongs to the VHL family.

29088:NCAPD2
gene id: 29088:NCAPD2
uniprot id: A0A2Y9HA92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

29088:HDAC3
gene id: 29088:HDAC3
uniprot id: A0A2Y9I1Q7
uniprot id: A0A2Y9I1Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Belongs to the histone deacetylase family. HD type 1 subfamily.
messages: Nucleus

29088:CBR3
gene id: 29088:CBR3
uniprot id: A0A2Y9G3M5
uniprot id: A0A2Y9G3Q5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Monomer.

29088:LOC110580615
gene id: 29088:LOC110580615
uniprot id: A0A2Y9H7X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

29088:IMMT
gene id: 29088:IMMT
uniprot id: A0A2Y9HNI0
uniprot id: A0A8M1MNU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

29088:SPSB3
gene id: 29088:SPSB3
uniprot id: A0A2Y9HPT9
uniprot id: A0A2Y9HV32
names: Function
names: Similarity
messages: Belongs to the SPSB family.
messages: May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

29088:B3GALT6
gene id: 29088:B3GALT6
uniprot id: A0A8M1MB27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:CLUAP1
gene id: 29088:CLUAP1
uniprot id: A0A2Y9HPT0
uniprot id: A0A8M1MCK3
uniprot id: A0A8M1MG20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

29088:ABCC8
gene id: 29088:ABCC8
uniprot id: A0A2Y9GQD4
uniprot id: A0A2Y9GQJ1
uniprot id: A0A2Y9GUG6
uniprot id: A0A2Y9GW60
names: Subunit
messages: Interacts with KCNJ11.

29088:LOC110585121
gene id: 29088:LOC110585121
uniprot id: A0A8M1MPB4
names: Similarity
messages: Belongs to the 14-3-3 family.

29088:GATA4
gene id: 29088:GATA4
uniprot id: A0A2Y9HSM0
uniprot id: A0A2Y9HSM5
uniprot id: A0A8M1M420
names: Subcellular Location Annotation
messages: Nucleus

29088:GDNF
gene id: 29088:GDNF
uniprot id: A0A2Y9HQL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

29088:NAA35
gene id: 29088:NAA35
uniprot id: A0A2Y9G791
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Involved in regulation of apoptosis and proliferation of smooth muscle cells.
messages: Belongs to the MAK10 family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
messages: Cytoplasm

29088:KCNH8
gene id: 29088:KCNH8
uniprot id: A0A2Y9G9K7
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

29088:LOC110585816
gene id: 29088:LOC110585816
uniprot id: A0A2Y9HIM4
uniprot id: A0A2Y9HJ08
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

29088:OPN1SW
gene id: 29088:OPN1SW
uniprot id: A0A2Y9HTG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Photoreceptor inner segment
messages: photoreceptor outer segment

29088:PTH1R
gene id: 29088:PTH1R
uniprot id: A0A2Y9GZW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

29088:LOC123323387
gene id: 29088:LOC123323387
uniprot id: A0A8M1M539
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:ABRAXAS2
gene id: 29088:ABRAXAS2
uniprot id: A0A2Y9I631
names: Subcellular Location Annotation
messages: Nucleus

29088:CRABP2
gene id: 29088:CRABP2
uniprot id: A0A2Y9GJJ6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:MC2R
gene id: 29088:MC2R
uniprot id: A0A2Y9GHR4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MRAP; increasing ligand-sensitivity and generation of cAMP. Interacts with MRAP2; competing with MRAP for binding to MC2R and impairing the binding of corticotropin (ACTH).
messages: Membrane

29088:PATZ1
gene id: 29088:PATZ1
uniprot id: A0A2Y9I561
uniprot id: A0A2Y9I5B8
uniprot id: A0A2Y9I5W3
uniprot id: A0A2Y9ICH1
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110586898
gene id: 29088:LOC110586898
uniprot id: A0A2Y9HST5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

29088:DRC7
gene id: 29088:DRC7
uniprot id: A0A2Y9I7V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC7 family.
messages: cilium axoneme
messages: flagellum
messages: flagellum axoneme

29088:GFUS
gene id: 29088:GFUS
uniprot id: A0A2Y9H2J2
uniprot id: A0A2Y9H4K0
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

29088:LOC110573176
gene id: 29088:LOC110573176
uniprot id: A0A2Y9GE19
uniprot id: A0A8M1MWZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the intermediate filament family.
messages: GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
messages: Interacts with SYNM.

29088:PRLHR
gene id: 29088:PRLHR
uniprot id: A0A2Y9HVP2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:LOC110585541
gene id: 29088:LOC110585541
uniprot id: A0A2Y9HHX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TRAPPC9
gene id: 29088:TRAPPC9
uniprot id: A0A2Y9GZ21
uniprot id: A0A8M1M9R9
names: Similarity
messages: Belongs to the NIBP family.

29088:CDH18
gene id: 29088:CDH18
uniprot id: A0A2Y9I2T8
uniprot id: A0A2Y9I7D6
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

29088:TP53
gene id: 29088:TP53
uniprot id: A0A2Y9HEV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Mitochondrion matrix
messages: Nucleus
messages: PML body
messages: centrosome

29088:TBCB
gene id: 29088:TBCB
uniprot id: A0A2Y9HXZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCB family.
messages: Cytoplasm

29088:DLL1
gene id: 29088:DLL1
uniprot id: A0A2Y9HB84
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

29088:TUBGCP3
gene id: 29088:TUBGCP3
uniprot id: A0A2Y9HJ47
uniprot id: A0A8M1M6E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

29088:LOC110577409
gene id: 29088:LOC110577409
uniprot id: A0A2Y9GT76
names: Similarity
messages: Belongs to the intermediate filament family.

29088:LOC123325526
gene id: 29088:LOC123325526
uniprot id: A0A2Y9GUW2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:VPS33A
gene id: 29088:VPS33A
uniprot id: A0A2Y9HWW6
uniprot id: A0A8M1MTQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: clathrin-coated vesicle

29088:CENPC
gene id: 29088:CENPC
uniprot id: A0A8M1MC45
names: Similarity
messages: Belongs to the CENP-C/MIF2 family.

29088:FAM161A
gene id: 29088:FAM161A
uniprot id: A0A2Y9HSY3
uniprot id: A0A2Y9HTF0
names: Similarity
messages: Belongs to the FAM161 family.

29088:NPTXR
gene id: 29088:NPTXR
uniprot id: A0A2Y9H1W4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:IDNK
gene id: 29088:IDNK
uniprot id: A0A2Y9G413
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

29088:WEE1
gene id: 29088:WEE1
uniprot id: A0A2Y9GW01
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

29088:CLSTN2
gene id: 29088:CLSTN2
uniprot id: A0A8M1M322
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:TBC1D24
gene id: 29088:TBC1D24
uniprot id: A0A2Y9HQ79
uniprot id: A0A8M1MD55
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Interacts with ARF6.
messages: Membrane
messages: Presynapse
messages: Synapse

29088:TRNT1
gene id: 29088:TRNT1
uniprot id: A0A2Y9HGE9
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

29088:MRFAP1
gene id: 29088:MRFAP1
uniprot id: A0A2Y9G542
names: Similarity
messages: Belongs to the MORF4 family-associated protein family.

29088:FABP12
gene id: 29088:FABP12
uniprot id: A0A2Y9GYC0
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:PLK3
gene id: 29088:PLK3
uniprot id: A0A2Y9GNM8
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

29088:PPFIA3
gene id: 29088:PPFIA3
uniprot id: A0A8M1M0D9
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

29088:LOC110576407
gene id: 29088:LOC110576407
uniprot id: A0A2Y9GQ39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:APEH
gene id: 29088:APEH
uniprot id: A0A2Y9GTG1
uniprot id: A0A2Y9GTJ7
uniprot id: A0A2Y9GTK9
uniprot id: A0A2Y9GXN7
uniprot id: A0A2Y9GZ97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S9C family.
messages: Cytoplasm
messages: Homotetramer.
messages: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.

29088:LYPD2
gene id: 29088:LYPD2
uniprot id: A0A2Y9H3L3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:ERMN
gene id: 29088:ERMN
uniprot id: A0A2Y9I9I0
uniprot id: A0A2Y9IBX8
names: Function
names: Subunit
messages: Binds actin.
messages: Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS.

29088:LTN1
gene id: 29088:LTN1
uniprot id: A0A2Y9G3Y9
uniprot id: A0A8M1MNK9
uniprot id: A0A8M1MXG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

29088:LOC110593205
gene id: 29088:LOC110593205
uniprot id: A0A2Y9I8A1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110585307
gene id: 29088:LOC110585307
uniprot id: A0A2Y9HNJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:EIF2B2
gene id: 29088:EIF2B2
uniprot id: A0A2Y9G8E3
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

29088:DNAH2
gene id: 29088:DNAH2
uniprot id: A0A8M1MWC2
names: Similarity
messages: Belongs to the dynein heavy chain family.

29088:LOC110581389
gene id: 29088:LOC110581389
uniprot id: A0A2Y9H5E7
uniprot id: A0A2Y9H5H2
names: Similarity
messages: Belongs to the NipSnap family.

29088:LOC110576880
gene id: 29088:LOC110576880
uniprot id: A0A2Y9HYR7
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

29088:DYNC1H1
gene id: 29088:DYNC1H1
uniprot id: A0A2Y9G934
uniprot id: A0A2Y9G968
uniprot id: A0A2Y9GBQ8
names: Similarity
messages: Belongs to the dynein heavy chain family.

29088:EDEM3
gene id: 29088:EDEM3
uniprot id: A0A2Y9GLK2
uniprot id: A0A8M1MGU5
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

29088:IHH
gene id: 29088:IHH
uniprot id: A0A2Y9I9B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: Secreted
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

29088:YIPF7
gene id: 29088:YIPF7
uniprot id: A0A8M1M4G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

29088:LOC110575705
gene id: 29088:LOC110575705
uniprot id: A0A2Y9GMM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

29088:LOC110592393
gene id: 29088:LOC110592393
uniprot id: A0A2Y9I9W2
names: Similarity
names: Subunit
messages: Belongs to the rtf2 family.
messages: Interacts with DDI2; probably also interacts with DDI1.

29088:GIPC2
gene id: 29088:GIPC2
uniprot id: A0A2Y9G431
names: Similarity
messages: Belongs to the GIPC family.

29088:MEIS2
gene id: 29088:MEIS2
uniprot id: A0A2Y9HI60
uniprot id: A0A2Y9HPE9
uniprot id: A0A8M1MK89
uniprot id: A0A8M1MK94
uniprot id: A0A8M1MM95
uniprot id: A0A8M1MMA1
uniprot id: A0A8M1MNK8
uniprot id: A0A8M1MUC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

29088:SFTPD
gene id: 29088:SFTPD
uniprot id: A0A2Y9HWA7
names: Similarity
names: Subunit
messages: Belongs to the SFTPD family.
messages: Oligomeric complex of 4 set of homotrimers.

29088:BORA
gene id: 29088:BORA
uniprot id: A0A8M1M5Q8
uniprot id: A0A8M1M9B2
names: Similarity
messages: Belongs to the BORA family.

29088:LOC110586591
gene id: 29088:LOC110586591
uniprot id: A0A8M1MAD4
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

29088:LOC110576489
gene id: 29088:LOC110576489
uniprot id: A0A2Y9GPY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110585870
gene id: 29088:LOC110585870
uniprot id: A0A8M1MJU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

29088:LOC110584884
gene id: 29088:LOC110584884
uniprot id: A0A8M1MN42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

29088:OVOL3
gene id: 29088:OVOL3
uniprot id: A0A2Y9HY29
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110585519
gene id: 29088:LOC110585519
uniprot id: A0A2Y9HPI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:XPNPEP1
gene id: 29088:XPNPEP1
uniprot id: A0A2Y9I118
uniprot id: A0A2Y9I2P9
uniprot id: A0A8M1MFD0
uniprot id: A0A8M1MIS7
uniprot id: A0A8M1MP31
names: Similarity
messages: Belongs to the peptidase M24B family.

29088:LOC110593571
gene id: 29088:LOC110593571
uniprot id: A0A8M1MB96
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ATXN1L
gene id: 29088:ATXN1L
uniprot id: A0A2Y9IJ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

29088:MDFI
gene id: 29088:MDFI
uniprot id: A0A2Y9H7Z9
names: Similarity
messages: Belongs to the MDFI family.

29088:HEATR5A
gene id: 29088:HEATR5A
uniprot id: A0A2Y9HN48
names: Similarity
messages: Belongs to the HEATR5 family.

29088:CHAF1A
gene id: 29088:CHAF1A
uniprot id: A0A2Y9IAE3
uniprot id: A0A2Y9IAH2
uniprot id: A0A2Y9IEW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHAF1A family.
messages: Nucleus

29088:AASDH
gene id: 29088:AASDH
uniprot id: A0A2Y9I083
uniprot id: A0A8M1M4F8
uniprot id: A0A8M1M832
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

29088:KCNE4
gene id: 29088:KCNE4
uniprot id: A0A2Y9IC21
names: Similarity
messages: Belongs to the potassium channel KCNE family.

29088:SRP14
gene id: 29088:SRP14
uniprot id: A0A2Y9HI12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm
messages: Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

29088:SBF1
gene id: 29088:SBF1
uniprot id: A0A8M1MBR0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

29088:MZT1
gene id: 29088:MZT1
uniprot id: A0A2Y9HP38
names: Function
names: Similarity
messages: Belongs to the MOZART1 family.
messages: Required for gamma-tubulin complex recruitment to the centrosome.

29088:LOC110572105
gene id: 29088:LOC110572105
uniprot id: A0A2Y9GAQ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:LFNG
gene id: 29088:LFNG
uniprot id: A0A8M1MBQ1
names: Subcellular Location Annotation
messages: Membrane

29088:PARP11
gene id: 29088:PARP11
uniprot id: A0A8M1MCW6
uniprot id: A0A8M1ME99
uniprot id: A0A8M1MJ33
names: Similarity
messages: Belongs to the ARTD/PARP family.

29088:LOC110574471
gene id: 29088:LOC110574471
uniprot id: A0A2Y9GIB5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:AFAP1L1
gene id: 29088:AFAP1L1
uniprot id: A0A8M1MHM2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in podosome and invadosome formation.
messages: invadopodium
messages: podosome

29088:TRMT61A
gene id: 29088:TRMT61A
uniprot id: A0A2Y9G8W8
uniprot id: A0A8M1MMW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

29088:LOC110574958
gene id: 29088:LOC110574958
uniprot id: A0A2Y9GK51
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:BAK1
gene id: 29088:BAK1
uniprot id: A0A2Y9GM02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

29088:LOC123326498
gene id: 29088:LOC123326498
uniprot id: A0A8M1MYI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

29088:MED19
gene id: 29088:MED19
uniprot id: A0A2Y9GMU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

29088:HDAC7
gene id: 29088:HDAC7
uniprot id: A0A2Y9I9Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

29088:ZW10
gene id: 29088:ZW10
uniprot id: A0A2Y9HJH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZW10 family.
messages: kinetochore

29088:GSX1
gene id: 29088:GSX1
uniprot id: A0A2Y9G834
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110584242
gene id: 29088:LOC110584242
uniprot id: A0A2Y9HDU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

29088:GPR101
gene id: 29088:GPR101
uniprot id: A0A2Y9GMI3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:ADAM12
gene id: 29088:ADAM12
uniprot id: A0A2Y9IB26
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:MRPL27
gene id: 29088:MRPL27
uniprot id: A0A2Y9I739
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

29088:FAM3C
gene id: 29088:FAM3C
uniprot id: A0A2Y9I065
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

29088:ADAT2
gene id: 29088:ADAT2
uniprot id: A0A2Y9HBU9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily.
messages: Probably participates in deamination of adenosine-34 to inosine in many tRNAs.

29088:GDPGP1
gene id: 29088:GDPGP1
uniprot id: A0A2Y9GB21
uniprot id: A0A2Y9GFB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDPGP1 family.
messages: Cytoplasm
messages: Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.

29088:DNAAF1
gene id: 29088:DNAAF1
uniprot id: A0A2Y9I336
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF1 family.
messages: cilium

29088:CRYBB3
gene id: 29088:CRYBB3
uniprot id: A0A2Y9IAC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

29088:LIG3
gene id: 29088:LIG3
uniprot id: A0A2Y9I6E8
uniprot id: A0A2Y9I6S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

29088:TSHR
gene id: 29088:TSHR
uniprot id: A0A2Y9G8D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Interacts with heterodimer GPHA2:GPHB5; this interaction stimulates cAMP production. Interacts (via the PDZ-binding motif) with SCRIB; regulates TSHR trafficking and function.
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

29088:SELENOK
gene id: 29088:SELENOK
uniprot id: A0A2Y9HGH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein K family.
messages: Endoplasmic reticulum membrane

29088:LOC110579314
gene id: 29088:LOC110579314
uniprot id: A0A2Y9H3P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:IL12A
gene id: 29088:IL12A
uniprot id: A0A2Y9I7V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity. Mechanistically, exerts its biological effects through a receptor composed of IL12R1 and IL12R2 subunits. Binding to the receptor results in the rapid tyrosine phosphorylation of a number of cellular substrates including the JAK family kinases TYK2 and JAK2. In turn, recruited STAT4 gets phosphorylated and translocates to the nucleus where it regulates cytokine/growth factor responsive genes. As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and functions also as an immune-suppressive cytokine. Mediates biological events through unconventional receptors composed of IL12RB2 and gp130/IL6ST heterodimers or homodimers. Signaling requires the transcription factors STAT1 and STAT4, which form a unique heterodimer that binds to distinct DNA sites.
messages: Secreted

29088:PTTG1
gene id: 29088:PTTG1
uniprot id: A0A2Y9HPH1
uniprot id: A0A2Y9HUQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

29088:IKBKE
gene id: 29088:IKBKE
uniprot id: A0A2Y9GSG2
uniprot id: A0A2Y9GSK7
uniprot id: A0A2Y9GSR4
uniprot id: A0A2Y9GY61
names: Subcellular Location Annotation
messages: Cytoplasm

29088:IFNAR1
gene id: 29088:IFNAR1
uniprot id: A0A2Y9G3S5
uniprot id: A0A8M1MAE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II cytokine receptor family.
messages: Cell membrane
messages: Endosome
messages: Heterodimer with IFNAR2.
messages: Late endosome
messages: Lysosome
messages: Membrane
messages: Together with IFNAR2, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, epsilon, omega and kappa). Type I interferon binding activates the JAK-STAT signaling cascade. Can also act independently of IFNAR2: form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway.

29088:USP14
gene id: 29088:USP14
uniprot id: A0A2Y9GR73
uniprot id: A0A8M1MWL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase C19 family. USP14/UBP6 subfamily.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Homodimer (Potential). Associates with the 26S proteasome. Interacts with FANCC, CXCR4 and ERN1. Interacts with TRIM14; this interaction recruits USP14 to cleave ubiquitin chains of CGAS.

29088:GRB14
gene id: 29088:GRB14
uniprot id: A0A2Y9I3Q6
uniprot id: A0A2Y9I3X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

29088:GSS
gene id: 29088:GSS
uniprot id: A0A2Y9H0C9
uniprot id: A0A2Y9H549
uniprot id: A0A8M1MMC6
uniprot id: A0A8M1MQM5
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

29088:SIN3A
gene id: 29088:SIN3A
uniprot id: A0A2Y9HD95
uniprot id: A0A2Y9HJH7
uniprot id: A0A2Y9HJV2
uniprot id: A0A8M1MKG6
names: Subcellular Location Annotation
messages: Nucleus

29088:LARP7
gene id: 29088:LARP7
uniprot id: A0A2Y9GM14
uniprot id: A0A2Y9GQN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LARP7 family.
messages: nucleoplasm

29088:MSRB1
gene id: 29088:MSRB1
uniprot id: A0A2Y9HQL0
uniprot id: A0A8M1MJC7
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.

29088:LOC110580906
gene id: 29088:LOC110580906
uniprot id: A0A2Y9H8Y3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.
messages: Belongs to the osteocalcin/matrix Gla protein family.
messages: Requires vitamin K-dependent gamma-carboxylation for its function.
messages: Secreted

29088:LOC110586152
gene id: 29088:LOC110586152
uniprot id: A0A8M1MN19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

29088:FAM133A
gene id: 29088:FAM133A
uniprot id: A0A2Y9HBP6
names: Similarity
messages: Belongs to the FAM133 family.

29088:CUTC
gene id: 29088:CUTC
uniprot id: A0A2Y9HUJ5
uniprot id: A0A2Y9HV37
uniprot id: A0A2Y9HV39
uniprot id: A0A2Y9HV44
uniprot id: A0A2Y9HZW0
names: Similarity
messages: Belongs to the CutC family.

29088:ITGA11
gene id: 29088:ITGA11
uniprot id: A0A2Y9HIF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

29088:ZFX
gene id: 29088:ZFX
uniprot id: A0A2Y9IIW8
names: Subcellular Location Annotation
messages: Nucleus

29088:YKT6
gene id: 29088:YKT6
uniprot id: A0A2Y9IAN7
uniprot id: A0A8M1MPX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

29088:CHST1
gene id: 29088:CHST1
uniprot id: A0A2Y9GRI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

29088:B3GLCT
gene id: 29088:B3GLCT
uniprot id: A0A8M1M941
names: Subcellular Location Annotation
messages: Membrane

29088:AGAP2
gene id: 29088:AGAP2
uniprot id: A0A2Y9GYU6
uniprot id: A0A8M1MDS3
names: Similarity
messages: Belongs to the centaurin gamma-like family.

29088:LALBA
gene id: 29088:LALBA
uniprot id: A0A2Y9I9C4
uniprot id: A0A2Y9I9Y9
uniprot id: A0A2Y9IGL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Lactose synthase (LS) is a heterodimer of a catalytic component, beta1,4-galactosyltransferase (beta4Gal-T1) and a regulatory component, alpha-lactalbumin (LA).
messages: Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.

29088:LOC110583620
gene id: 29088:LOC110583620
uniprot id: A0A2Y9HIP5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:SLCO5A1
gene id: 29088:SLCO5A1
uniprot id: A0A2Y9GXV4
uniprot id: A0A2Y9GY51
uniprot id: A0A2Y9H2C3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:PJVK
gene id: 29088:PJVK
uniprot id: A0A2Y9I5D2
names: Similarity
messages: Belongs to the gasdermin family.

29088:ST6GALNAC2
gene id: 29088:ST6GALNAC2
uniprot id: A0A2Y9GC80
uniprot id: A0A2Y9GF51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

29088:LOC110575151
gene id: 29088:LOC110575151
uniprot id: A0A2Y9GPE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

29088:TMSB15B
gene id: 29088:TMSB15B
uniprot id: A0A2Y9G4A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

29088:CAPN9
gene id: 29088:CAPN9
uniprot id: A0A2Y9HJJ9
names: Similarity
messages: Belongs to the peptidase C2 family.

29088:SLC45A3
gene id: 29088:SLC45A3
uniprot id: A0A2Y9GSK5
names: Subcellular Location Annotation
messages: Membrane

29088:RAG1
gene id: 29088:RAG1
uniprot id: A0A2Y9GME8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAG1 family.
messages: Binds 1 divalent metal cation per subunit. Mg(2+) or Mn(2+).
messages: Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.
messages: Homodimer.
messages: Nucleus
messages: The NBD (nonamer binding) DNA-binding domain mediates the specific binding to the nonamer RSS motif by forming a tightly interwoven homodimer that binds and synapses 2 nonamer elements, with each NBD making contact with both DNA molecules. Each RSS is composed of well-conserved heptamer (consensus 5'-CACAGTG-3') and nonamer (consensus 5'-ACAAAAACC-3') sequences separated by a spacer of either 12 bp or 23 bp.

29088:ACTL10
gene id: 29088:ACTL10
uniprot id: A0A2Y9H4U1
names: Similarity
messages: Belongs to the actin family.

29088:GREB1
gene id: 29088:GREB1
uniprot id: A0A2Y9HNC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

29088:MORF4L1
gene id: 29088:MORF4L1
uniprot id: A0A8M1MK37
names: Subcellular Location Annotation
messages: Nucleus

29088:KIFC1
gene id: 29088:KIFC1
uniprot id: A0A8M1MJ73
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:NOX5
gene id: 29088:NOX5
uniprot id: A0A8M1MNH6
names: Subcellular Location Annotation
messages: Membrane

29088:NCR3
gene id: 29088:NCR3
uniprot id: A0A8M1MH52
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the natural cytotoxicity receptor (NCR) family.
messages: Cell membrane
messages: Homodimer in the unliganted form. Interacts with CD3Z. Interacts with and is activated by binding to NCR3LG1. Interacts with and is activated by binding to BAG6.
messages: Membrane

29088:SPRY2
gene id: 29088:SPRY2
uniprot id: A0A2Y9HPK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sprouty family.
messages: ruffle membrane

29088:CLDN23
gene id: 29088:CLDN23
uniprot id: A0A2Y9HKA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

29088:TLE1
gene id: 29088:TLE1
uniprot id: A0A2Y9H0G7
uniprot id: A0A2Y9H0H1
uniprot id: A0A2Y9H0M0
uniprot id: A0A2Y9H0N0
uniprot id: A0A2Y9H701
uniprot id: A0A8M1MRH3
uniprot id: A0A8M1MRH9
uniprot id: A0A8M1MRI4
uniprot id: A0A8M1MRI7
uniprot id: A0A8M1MRI9
uniprot id: A0A8M1MRJ2
uniprot id: A0A8M1MRJ4
uniprot id: A0A8M1MRJ7
uniprot id: A0A8M1MRK2
uniprot id: A0A8M1MTD3
uniprot id: A0A8M1MTD8
uniprot id: A0A8M1MTE1
uniprot id: A0A8M1MTE6
uniprot id: A0A8M1MTF2
uniprot id: A0A8M1MUR0
uniprot id: A0A8M1MUR3
uniprot id: A0A8M1MUR8
uniprot id: A0A8M1MUS3
uniprot id: A0A8M1MUS8
uniprot id: A0A8M1MYI7
uniprot id: A0A8M1MYI8
uniprot id: A0A8M1MYI9
uniprot id: A0A8M1MYJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

29088:CELF3
gene id: 29088:CELF3
uniprot id: A0A2Y9GWT1
uniprot id: A0A2Y9GWW0
uniprot id: A0A2Y9H0X3
uniprot id: A0A2Y9H321
uniprot id: A0A8M1M8B3
uniprot id: A0A8M1M8B8
uniprot id: A0A8M1M8C4
uniprot id: A0A8M1M8D0
uniprot id: A0A8M1M8K3
uniprot id: A0A8M1M8K8
uniprot id: A0A8M1M8L3
uniprot id: A0A8M1M8L7
uniprot id: A0A8M1MAQ9
uniprot id: A0A8M1MAR4
uniprot id: A0A8M1MAR8
uniprot id: A0A8M1MAS3
uniprot id: A0A8M1MC39
uniprot id: A0A8M1MC43
uniprot id: A0A8M1MC48
uniprot id: A0A8M1MC51
uniprot id: A0A8M1MGP5
uniprot id: A0A8M1MGQ0
uniprot id: A0A8M1MGQ7
uniprot id: A0A8M1MGR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

29088:CLDN14
gene id: 29088:CLDN14
uniprot id: A0A2Y9G3P7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

29088:LOC110580718
gene id: 29088:LOC110580718
uniprot id: A0A8M1MAC4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates.

29088:ARHGAP33
gene id: 29088:ARHGAP33
uniprot id: A0A8M1MZG9
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

29088:GANC
gene id: 29088:GANC
uniprot id: A0A2Y9HHZ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

29088:LOC110586070
gene id: 29088:LOC110586070
uniprot id: A0A2Y9HJQ8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:NMBR
gene id: 29088:NMBR
uniprot id: A0A2Y9HAS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:CNOT8
gene id: 29088:CNOT8
uniprot id: A0A2Y9HMQ0
uniprot id: A0A2Y9HN12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

29088:CWC15
gene id: 29088:CWC15
uniprot id: A0A2Y9G6T8
names: Similarity
messages: Belongs to the CWC15 family.

29088:RARRES1
gene id: 29088:RARRES1
uniprot id: A0A2Y9I9V9
uniprot id: A0A8M1MB14
names: Similarity
messages: Belongs to the protease inhibitor I47 (latexin) family.

29088:LOC110591355
gene id: 29088:LOC110591355
uniprot id: A0A2Y9I6S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

29088:CCDC181
gene id: 29088:CCDC181
uniprot id: A0A2Y9GGS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC181 family.
messages: Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
messages: cytoskeleton
messages: flagellum

29088:ADAMTS17
gene id: 29088:ADAMTS17
uniprot id: A0A2Y9GAW6
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:MICOS13
gene id: 29088:MICOS13
uniprot id: A0A2Y9IH40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic13 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

29088:PAX9
gene id: 29088:PAX9
uniprot id: A0A2Y9I4J7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with KDM5B.
messages: Nucleus
messages: Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs.

29088:MTCP1
gene id: 29088:MTCP1
uniprot id: A0A2Y9GK79
names: Similarity
messages: Belongs to the TCL1 family.

29088:BMP3
gene id: 29088:BMP3
uniprot id: A0A2Y9I2C3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer.
messages: Secreted

29088:ADRA1B
gene id: 29088:ADRA1B
uniprot id: A0A2Y9HUJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

29088:UBE2C
gene id: 29088:UBE2C
uniprot id: A0A2Y9H4E3
uniprot id: A0A8M1MNM5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:LOC123326184
gene id: 29088:LOC123326184
uniprot id: A0A8M1MRB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:RABGGTB
gene id: 29088:RABGGTB
uniprot id: A0A2Y9G454
uniprot id: A0A2Y9G4K0
uniprot id: A0A2Y9G6L9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

29088:PAX8
gene id: 29088:PAX8
uniprot id: A0A2Y9HNT4
names: Subcellular Location Annotation
messages: Nucleus

29088:AZGP1
gene id: 29088:AZGP1
uniprot id: A0A2Y9GA67
names: Similarity
messages: Belongs to the MHC class I family.

29088:ANHX
gene id: 29088:ANHX
uniprot id: A0A8M1MSL0
names: Subcellular Location Annotation
messages: Nucleus

29088:IDH3A
gene id: 29088:IDH3A
uniprot id: A0A2Y9GBC9
uniprot id: A0A2Y9GBD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

29088:DACT1
gene id: 29088:DACT1
uniprot id: A0A2Y9HZZ3
uniprot id: A0A8M1MJX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dapper family.
messages: Cytoplasm

29088:PLEC
gene id: 29088:PLEC
uniprot id: A0A8M1M9U1
uniprot id: A0A8M1MA22
uniprot id: A0A8M1MC61
names: Subcellular Location Annotation
messages: cytoskeleton

29088:MX2
gene id: 29088:MX2
uniprot id: A0A2Y9G9L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: Cytoplasm

29088:EME1
gene id: 29088:EME1
uniprot id: A0A2Y9I741
names: Similarity
messages: Belongs to the EME1/MMS4 family.

29088:VTI1B
gene id: 29088:VTI1B
uniprot id: A0A2Y9G8U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

29088:POLR3F
gene id: 29088:POLR3F
uniprot id: A0A2Y9I459
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

29088:WNT6
gene id: 29088:WNT6
uniprot id: A0A2Y9I4L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

29088:GNB3
gene id: 29088:GNB3
uniprot id: A0A2Y9H493
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

29088:LOC110574751
gene id: 29088:LOC110574751
uniprot id: A0A2Y9GJ74
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

29088:DNM2
gene id: 29088:DNM2
uniprot id: A0A2Y9I9K0
uniprot id: A0A2Y9I9M3
uniprot id: A0A2Y9IA75
uniprot id: A0A2Y9IGS8
uniprot id: A0A2Y9IGT3
uniprot id: A0A8M1M9V0
uniprot id: A0A8M1MC79
uniprot id: A0A8M1MDJ9
uniprot id: A0A8M1MI61
uniprot id: A0A8M1MIB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: cytoskeleton

29088:HTATSF1
gene id: 29088:HTATSF1
uniprot id: A0A2Y9GME7
names: Similarity
messages: Belongs to the HTATSF1 family.

29088:POLR3H
gene id: 29088:POLR3H
uniprot id: A0A2Y9GUZ2
uniprot id: A0A2Y9GZ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

29088:CCNP
gene id: 29088:CCNP
uniprot id: A0A2Y9I353
names: Similarity
messages: Belongs to the cyclin family.

29088:LOC110578840
gene id: 29088:LOC110578840
uniprot id: A0A8M1MH84
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autoacetylation strongly increases tubulin acetylation.
messages: Belongs to the acetyltransferase ATAT1 family.
messages: Component of the BBSome complex. Interacts with AP2 alpha-adaptins, including AP2A2, but not with AP1 gamma-adaptin (AP1G1/AP1G2); this interaction is required for efficient alpha-tubulin acetylation, hence clathrin-coated pits are sites of microtubule acetylation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.
messages: axon
messages: clathrin-coated pit
messages: cytoskeleton
messages: focal adhesion
messages: spindle

29088:LOC110594317
gene id: 29088:LOC110594317
uniprot id: A0A2Y9IGF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C14A family.
messages: Cytoplasm

29088:SOX1
gene id: 29088:SOX1
uniprot id: A0A8M1M9R7
names: Subcellular Location Annotation
messages: Nucleus

29088:PLCB2
gene id: 29088:PLCB2
uniprot id: A0A2Y9HH23
uniprot id: A0A2Y9HN87
uniprot id: A0A2Y9HNL6
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

29088:TMEM150C
gene id: 29088:TMEM150C
uniprot id: A0A2Y9I9B0
names: Subcellular Location Annotation
messages: Membrane

29088:AMIGO3
gene id: 29088:AMIGO3
uniprot id: A0A2Y9GXN1
names: Similarity
messages: Belongs to the immunoglobulin superfamily. AMIGO family.

29088:CDH8
gene id: 29088:CDH8
uniprot id: A0A2Y9I7K0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

29088:NALF1
gene id: 29088:NALF1
uniprot id: A0A2Y9HJ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NALF family.
messages: Membrane

29088:TLX1
gene id: 29088:TLX1
uniprot id: A0A2Y9HW44
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110581125
gene id: 29088:LOC110581125
uniprot id: A0A2Y9HB70
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

29088:EOMES
gene id: 29088:EOMES
uniprot id: A0A2Y9G650
uniprot id: A0A2Y9G653
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

29088:LOC110577745
gene id: 29088:LOC110577745
uniprot id: A0A8M1MG81
uniprot id: A0A8M1MG84
names: Similarity
messages: Belongs to the NAC-beta family.

29088:GGT1
gene id: 29088:GGT1
uniprot id: A0A2Y9GW91
uniprot id: A0A2Y9H0N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

29088:LOC110587717
gene id: 29088:LOC110587717
uniprot id: A0A8M1M9A3
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:ATP2A2
gene id: 29088:ATP2A2
uniprot id: A0A2Y9HRJ5
uniprot id: A0A8M1MTR2
uniprot id: A0A8M1MYZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

29088:RSPO1
gene id: 29088:RSPO1
uniprot id: A0A2Y9GJY1
names: Similarity
messages: Belongs to the R-spondin family.

29088:APOA1
gene id: 29088:APOA1
uniprot id: A0A7F3SA42
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

29088:LEPROT
gene id: 29088:LEPROT
uniprot id: A0A2Y9GC44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

29088:CAPRIN2
gene id: 29088:CAPRIN2
uniprot id: A0A2Y9H3G7
uniprot id: A0A2Y9H3H8
uniprot id: A0A2Y9H3J0
uniprot id: A0A2Y9H8L0
uniprot id: A0A2Y9H8L2
uniprot id: A0A2Y9HA67
uniprot id: A0A8M1MAD7
uniprot id: A0A8M1MAL8
uniprot id: A0A8M1ME33
uniprot id: A0A8M1ME38
uniprot id: A0A8M1MIV8
uniprot id: A0A8M1MIW5
names: Similarity
messages: Belongs to the caprin family.

29088:AWAT2
gene id: 29088:AWAT2
uniprot id: A0A2Y9GBA4
uniprot id: A0A2Y9GFD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane

29088:LOC110570018
gene id: 29088:LOC110570018
uniprot id: A0A8M1MAB7
names: Subcellular Location Annotation
messages: Nucleus

29088:TPD52L3
gene id: 29088:TPD52L3
uniprot id: A0A2Y9GG38
names: Similarity
messages: Belongs to the TPD52 family.

29088:LOC110586096
gene id: 29088:LOC110586096
uniprot id: A0A2Y9HQE8
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

29088:LOC110579916
gene id: 29088:LOC110579916
uniprot id: A0A2Y9H0V5
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

29088:RTN4
gene id: 29088:RTN4
uniprot id: A0A2Y9HZ24
uniprot id: A0A2Y9HZ84
uniprot id: A0A2Y9I407
uniprot id: A0A2Y9I5W2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:HIBADH
gene id: 29088:HIBADH
uniprot id: A0A2Y9H0Y2
uniprot id: A0A8M1MRL3
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

29088:KRT18
gene id: 29088:KRT18
uniprot id: A0A2Y9HEL2
names: Similarity
messages: Belongs to the intermediate filament family.

29088:RXRA
gene id: 29088:RXRA
uniprot id: A0A8M1MR48
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

29088:LOC110581168
gene id: 29088:LOC110581168
uniprot id: A0A2Y9H4Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110591924
gene id: 29088:LOC110591924
uniprot id: A0A2Y9IAX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

29088:ASPHD2
gene id: 29088:ASPHD2
uniprot id: A0A2Y9I6E2
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

29088:GINS3
gene id: 29088:GINS3
uniprot id: A0A2Y9IEZ5
uniprot id: A0A8M1MZJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

29088:INTS9
gene id: 29088:INTS9
uniprot id: A0A2Y9HZE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

29088:LOC110578072
gene id: 29088:LOC110578072
uniprot id: A0A8M1MD33
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

29088:C7H5orf22
gene id: 29088:C7H5orf22
uniprot id: A0A2Y9HQ91
names: Similarity
messages: Belongs to the UPF0489 family.

29088:RALY
gene id: 29088:RALY
uniprot id: A0A2Y9GZA2
uniprot id: A0A2Y9H5N2
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

29088:CHURC1
gene id: 29088:CHURC1
uniprot id: A0A2Y9HZQ8
names: Similarity
messages: Belongs to the Churchill family.

29088:CCDC47
gene id: 29088:CCDC47
uniprot id: A0A2Y9G4W9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Rough endoplasmic reticulum membrane

29088:PTCD3
gene id: 29088:PTCD3
uniprot id: A0A2Y9HV15
uniprot id: A0A8M1MNF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS39 family.
messages: Mitochondrion

29088:TAS2R38
gene id: 29088:TAS2R38
uniprot id: A0A2Y9HA05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

29088:C14H12orf43
gene id: 29088:C14H12orf43
uniprot id: A0A2Y9IAB4
uniprot id: A0A8M1MT75
uniprot id: A0A8M1MT81
uniprot id: A0A8M1MWE5
uniprot id: A0A8M1MYV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUSTOS family.
messages: Nucleus envelope

29088:MET
gene id: 29088:MET
uniprot id: A0A2Y9HTP5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:LOC110575838
gene id: 29088:LOC110575838
uniprot id: A0A2Y9GRT5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110585522
gene id: 29088:LOC110585522
uniprot id: A0A8M1MK46
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SYNE3
gene id: 29088:SYNE3
uniprot id: A0A2Y9G8N9
uniprot id: A0A8M1MIY8
uniprot id: A0A8M1MIZ1
uniprot id: A0A8M1MMB4
names: Similarity
messages: Belongs to the nesprin family.

29088:GRHL1
gene id: 29088:GRHL1
uniprot id: A0A2Y9HMZ8
uniprot id: A0A2Y9HT91
uniprot id: A0A2Y9HUN0
names: Subcellular Location Annotation
messages: Nucleus

29088:NSMCE4A
gene id: 29088:NSMCE4A
uniprot id: A0A2Y9IDK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus
messages: telomere

29088:SPECC1L
gene id: 29088:SPECC1L
uniprot id: A0A2Y9GW38
uniprot id: A0A2Y9GWC2
uniprot id: A0A2Y9GWF2
uniprot id: A0A2Y9H0H7
uniprot id: A0A2Y9H2D2
uniprot id: A0A8M1MVJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytospin-A family.
messages: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.
messages: May interact with both microtubules and actin cytoskeleton.
messages: cytoskeleton
messages: gap junction
messages: spindle

29088:NSMCE1
gene id: 29088:NSMCE1
uniprot id: A0A2Y9HX60
uniprot id: A0A8M1MET0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus
messages: RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. Involved in maintenance of genome integrity, DNA damage response and DNA repair.
messages: telomere

29088:LOC110570685
gene id: 29088:LOC110570685
uniprot id: A0A8M1MK26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

29088:RUSF1
gene id: 29088:RUSF1
uniprot id: A0A2Y9HX79
uniprot id: A0A2Y9I289
names: Similarity
messages: Belongs to the RUS1 family.

29088:ORC4
gene id: 29088:ORC4
uniprot id: A0A2Y9I3L8
uniprot id: A0A2Y9I884
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication.
messages: Nucleus

29088:LOC110583243
gene id: 29088:LOC110583243
uniprot id: A0A2Y9HH64
names: Similarity
messages: Belongs to the fl(2)d family.

29088:RNF7
gene id: 29088:RNF7
uniprot id: A0A2Y9G8B1
uniprot id: A0A2Y9G9G8
uniprot id: A0A8M1MKA4
names: Similarity
messages: Belongs to the RING-box family.

29088:KMO
gene id: 29088:KMO
uniprot id: A0A2Y9GK53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
messages: Mitochondrion outer membrane

29088:GPRC5D
gene id: 29088:GPRC5D
uniprot id: A0A2Y9H487
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:OXTR
gene id: 29088:OXTR
uniprot id: A0A2Y9HMP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

29088:ABCB11
gene id: 29088:ABCB11
uniprot id: A0A2Y9IA97
uniprot id: A0A8M1M9R1
names: Subcellular Location Annotation
messages: Endosome

29088:LOC110590930
gene id: 29088:LOC110590930
uniprot id: A0A8M1MQV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

29088:EMC7
gene id: 29088:EMC7
uniprot id: A0A2Y9HHB2
uniprot id: A0A8M1MIZ7
names: Similarity
names: Subunit
messages: Belongs to the EMC7 family.
messages: Component of the ER membrane protein complex (EMC).

29088:ADCK2
gene id: 29088:ADCK2
uniprot id: A0A2Y9HA54
uniprot id: A0A2Y9HGQ2
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

29088:LOC110586313
gene id: 29088:LOC110586313
uniprot id: A0A2Y9HS12
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MYADML2
gene id: 29088:MYADML2
uniprot id: A0A2Y9GEE6
names: Subcellular Location Annotation
messages: Membrane

29088:TBX10
gene id: 29088:TBX10
uniprot id: A0A2Y9GNV1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

29088:PDE6G
gene id: 29088:PDE6G
uniprot id: A0A2Y9GBP1
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

29088:OXR1
gene id: 29088:OXR1
uniprot id: A0A2Y9GYV2
uniprot id: A0A2Y9GYW9
uniprot id: A0A2Y9H374
names: Similarity
messages: Belongs to the OXR1 family.

29088:LOC110589599
gene id: 29088:LOC110589599
uniprot id: A0A8M1MDU5
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

29088:LOC110592049
gene id: 29088:LOC110592049
uniprot id: A0A2Y9I8W3
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

29088:LOC110571781
gene id: 29088:LOC110571781
uniprot id: A0A2Y9G9C8
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:LOC110573024
gene id: 29088:LOC110573024
uniprot id: A0A8M1MJX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

29088:KRT3
gene id: 29088:KRT3
uniprot id: A0A2Y9GSZ9
names: Similarity
messages: Belongs to the intermediate filament family.

29088:UPK1B
gene id: 29088:UPK1B
uniprot id: A0A2Y9HEK5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Heterodimer with uroplakin-3A (UPK3A) or uroplakin-3B (UPK3B).
messages: Membrane

29088:LOC110581732
gene id: 29088:LOC110581732
uniprot id: A0A2Y9H6Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:STX17
gene id: 29088:STX17
uniprot id: A0A2Y9HD50
names: Similarity
messages: Belongs to the syntaxin family.

29088:TNFSF13
gene id: 29088:TNFSF13
uniprot id: A0A2Y9HET0
uniprot id: A0A2Y9HL26
names: Similarity
messages: Belongs to the tumor necrosis factor family.

29088:GATB
gene id: 29088:GATB
uniprot id: A0A2Y9HS87
uniprot id: A0A8M1M6A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

29088:MYO1A
gene id: 29088:MYO1A
uniprot id: A0A2Y9GUQ7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

29088:LIX1
gene id: 29088:LIX1
uniprot id: A0A2Y9I0G7
uniprot id: A0A2Y9I4Z9
uniprot id: A0A8M1MJ94
names: Similarity
messages: Belongs to the LIX1 family.

29088:LOC110575554
gene id: 29088:LOC110575554
uniprot id: A0A8M1M5I7
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

29088:MYO3B
gene id: 29088:MYO3B
uniprot id: A0A8M1MAJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: In the C-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

29088:LOC110585358
gene id: 29088:LOC110585358
uniprot id: A0A2Y9HHH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MAMDC4
gene id: 29088:MAMDC4
uniprot id: A0A2Y9H528
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:MTRF1
gene id: 29088:MTRF1
uniprot id: A0A2Y9HUL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

29088:HMBOX1
gene id: 29088:HMBOX1
uniprot id: A0A2Y9HRU8
uniprot id: A0A2Y9HSA0
uniprot id: A0A2Y9HSA3
uniprot id: A0A2Y9HX68
uniprot id: A0A2Y9HYR6
names: Subcellular Location Annotation
messages: Nucleus

29088:LYRM4
gene id: 29088:LYRM4
uniprot id: A0A2Y9HT82
names: Similarity
messages: Belongs to the complex I LYR family.

29088:CHRNA3
gene id: 29088:CHRNA3
uniprot id: A0A8M1MIT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:LOC110589976
gene id: 29088:LOC110589976
uniprot id: A0A2Y9HXP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

29088:CENPK
gene id: 29088:CENPK
uniprot id: A0A2Y9I5X9
uniprot id: A0A8M1MG63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-K/MCM22 family.
messages: Nucleus
messages: centromere

29088:NDUFS3
gene id: 29088:NDUFS3
uniprot id: A0A2Y9GPL7
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.

29088:LOC110591746
gene id: 29088:LOC110591746
uniprot id: A0A2Y9HE95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.
messages: Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.
messages: Nucleus

29088:GTF2E1
gene id: 29088:GTF2E1
uniprot id: A0A2Y9H949
names: Function
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

29088:SBDS
gene id: 29088:SBDS
uniprot id: A0A2Y9HWR6
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

29088:SLC12A6
gene id: 29088:SLC12A6
uniprot id: A0A2Y9HI29
uniprot id: A0A2Y9HP75
uniprot id: A0A8M1MM28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

29088:CPA2
gene id: 29088:CPA2
uniprot id: A0A2Y9HTG8
names: Similarity
messages: Belongs to the peptidase M14 family.

29088:PHKG1
gene id: 29088:PHKG1
uniprot id: A0A2Y9HWP1
uniprot id: A0A2Y9HWW4
uniprot id: A0A2Y9I1S4
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

29088:CPNE2
gene id: 29088:CPNE2
uniprot id: A0A2Y9IBW2
uniprot id: A0A8M1MY05
uniprot id: A0A8M1MZF6
names: Similarity
messages: Belongs to the copine family.

29088:PRDM14
gene id: 29088:PRDM14
uniprot id: A0A2Y9GYB1
names: Subcellular Location Annotation
messages: Nucleus

29088:HSP90AA1
gene id: 29088:HSP90AA1
uniprot id: A0A2Y9G9A5
uniprot id: A0A8M1MMM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 90 family.
messages: Melanosome

29088:ZEB2
gene id: 29088:ZEB2
uniprot id: A0A2Y9HIW2
uniprot id: A0A2Y9HQ58
uniprot id: A0A8M1MF12
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

29088:CLIC2
gene id: 29088:CLIC2
uniprot id: A0A2Y9GGM1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

29088:LOC110574728
gene id: 29088:LOC110574728
uniprot id: A0A2Y9GPE2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

29088:MED13
gene id: 29088:MED13
uniprot id: A0A2Y9I8B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

29088:ALDH1L1
gene id: 29088:ALDH1L1
uniprot id: A0A8M1M7Z6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

29088:CERS5
gene id: 29088:CERS5
uniprot id: A0A2Y9I946
uniprot id: A0A8M1MDY5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

29088:LOC110589248
gene id: 29088:LOC110589248
uniprot id: A0A8M1MNX3
names: Similarity
messages: Belongs to the proteasome subunit S10 family.

29088:NDUFA2
gene id: 29088:NDUFA2
uniprot id: A0A2Y9I1I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:TIMM17B
gene id: 29088:TIMM17B
uniprot id: A0A2Y9G6P4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

29088:LOC110586834
gene id: 29088:LOC110586834
uniprot id: A0A2Y9HMG0
uniprot id: A0A8M1MI71
uniprot id: A0A8M1MI73
uniprot id: A0A8M1MI76
uniprot id: A0A8M1MI77
uniprot id: A0A8M1MK96
uniprot id: A0A8M1MLK5
uniprot id: A0A8M1MS60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

29088:LOC110581197
gene id: 29088:LOC110581197
uniprot id: A0A2Y9H4R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:GORAB
gene id: 29088:GORAB
uniprot id: A0A2Y9GLR4
names: Similarity
messages: Belongs to the GORAB family.

29088:HSD17B7
gene id: 29088:HSD17B7
uniprot id: A0A2Y9HR52
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.

29088:THAP1
gene id: 29088:THAP1
uniprot id: A0A8M1M338
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: Interacts with PAWR. Component of a THAP1/THAP3-HCFC1-OGT complex that contains, either THAP1 or THAP3, HCFC1 and OGT. Interacts with OGT. Interacts (via the HBM) with HCFC1 (via the Kelch-repeat domain); the interaction recruits HCFC1 to the RRM1 promoter.
messages: nucleoplasm

29088:STK3
gene id: 29088:STK3
uniprot id: A0A2Y9GYF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

29088:LOC110585533
gene id: 29088:LOC110585533
uniprot id: A0A2Y9HIA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ELP2
gene id: 29088:ELP2
uniprot id: A0A2Y9GV89
uniprot id: A0A2Y9GWW9
uniprot id: A0A8M1MSK5
uniprot id: A0A8M1MSL1
uniprot id: A0A8M1MUE9
uniprot id: A0A8M1MVT1
uniprot id: A0A8M1MYR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

29088:CAPN14
gene id: 29088:CAPN14
uniprot id: A0A2Y9HNN0
names: Similarity
messages: Belongs to the peptidase C2 family.

29088:PTH2
gene id: 29088:PTH2
uniprot id: A0A2Y9GD47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

29088:MYH7B
gene id: 29088:MYH7B
uniprot id: A0A8M1MPC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

29088:TUBGCP4
gene id: 29088:TUBGCP4
uniprot id: A0A2Y9HIE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

29088:SLC35A5
gene id: 29088:SLC35A5
uniprot id: A0A2Y9H8S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

29088:LOC110576471
gene id: 29088:LOC110576471
uniprot id: A0A2Y9GQ41
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:IL17REL
gene id: 29088:IL17REL
uniprot id: A0A8M1MD02
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:PTPRN
gene id: 29088:PTPRN
uniprot id: A0A8M1M8L1
uniprot id: A0A8M1MEC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

29088:MAP3K11
gene id: 29088:MAP3K11
uniprot id: A0A2Y9GNC1
uniprot id: A0A2Y9GSB2
uniprot id: A0A8M1MX03
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

29088:NSG2
gene id: 29088:NSG2
uniprot id: A0A2Y9HXQ6
names: Similarity
messages: Belongs to the NSG family.

29088:GPRC5C
gene id: 29088:GPRC5C
uniprot id: A0A2Y9G8R2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:SLC2A11
gene id: 29088:SLC2A11
uniprot id: A0A2Y9GW75
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

29088:A4GNT
gene id: 29088:A4GNT
uniprot id: A0A2Y9G8D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

29088:ALDH3B2
gene id: 29088:ALDH3B2
uniprot id: A0A2Y9GNU1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

29088:LPAR6
gene id: 29088:LPAR6
uniprot id: A0A2Y9H5C6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:PIGO
gene id: 29088:PIGO
uniprot id: A0A2Y9H5H6
uniprot id: A0A2Y9H5I8
uniprot id: A0A2Y9H5L2
uniprot id: A0A2Y9HAY2
uniprot id: A0A2Y9HCA3
uniprot id: A0A8M1MYG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:UBE2E3
gene id: 29088:UBE2E3
uniprot id: A0A2Y9I3N3
uniprot id: A0A2Y9IAI3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:CAPG
gene id: 29088:CAPG
uniprot id: A0A2Y9HNE2
uniprot id: A0A8M1MNB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
messages: Cytoplasm
messages: Melanosome
messages: Nucleus
messages: lamellipodium
messages: ruffle

29088:ADAM8
gene id: 29088:ADAM8
uniprot id: A0A2Y9IAX2
uniprot id: A0A2Y9IDJ2
uniprot id: A0A8M1MFD5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:DCLK1
gene id: 29088:DCLK1
uniprot id: A0A2Y9G4J3
uniprot id: A0A2Y9G509
uniprot id: A0A2Y9G868
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

29088:FTSJ1
gene id: 29088:FTSJ1
uniprot id: A0A2Y9G765
uniprot id: A0A2Y9G984
uniprot id: A0A2Y9GAD0
uniprot id: A0A2Y9GAE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

29088:SLC6A5
gene id: 29088:SLC6A5
uniprot id: A0A8M1MS41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

29088:BCO2
gene id: 29088:BCO2
uniprot id: A0A8M1MMQ6
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

29088:FNTA
gene id: 29088:FNTA
uniprot id: A0A2Y9GDR5
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

29088:SLC15A1
gene id: 29088:SLC15A1
uniprot id: A0A2Y9HPL1
uniprot id: A0A2Y9HQ80
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

29088:LOC110575850
gene id: 29088:LOC110575850
uniprot id: A0A2Y9GTH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:UBQLN2
gene id: 29088:UBQLN2
uniprot id: A0A8M1M1F1
uniprot id: A0A8M1M1Q9
uniprot id: A0A8M1M5H6
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus
messages: autophagosome

29088:TSPAN6
gene id: 29088:TSPAN6
uniprot id: A0A2Y9HG28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

29088:LOC110572770
gene id: 29088:LOC110572770
uniprot id: A0A2Y9GCU7
uniprot id: A0A2Y9GCV6
uniprot id: A0A2Y9GH65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration.
messages: cytoskeleton

29088:UTS2R
gene id: 29088:UTS2R
uniprot id: A0A2Y9GBR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

29088:PHOSPHO2
gene id: 29088:PHOSPHO2
uniprot id: A0A2Y9I512
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

29088:PRKAA2
gene id: 29088:PRKAA2
uniprot id: A0A2Y9GKJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: Cytoplasm

29088:MB21D2
gene id: 29088:MB21D2
uniprot id: A0A2Y9H9F5
names: Similarity
messages: Belongs to the mab-21 family.

29088:LRRC42
gene id: 29088:LRRC42
uniprot id: A0A2Y9GNY1
uniprot id: A0A8M1MG92
names: Similarity
messages: Belongs to the LRRC42 family.

29088:LOC110573270
gene id: 29088:LOC110573270
uniprot id: A0A8M1M1U2
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:VAMP8
gene id: 29088:VAMP8
uniprot id: A0A2Y9HTK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

29088:LOC110581635
gene id: 29088:LOC110581635
uniprot id: A0A2Y9H6H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

29088:EVC
gene id: 29088:EVC
uniprot id: A0A2Y9G6D5
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

29088:GJC3
gene id: 29088:GJC3
uniprot id: A0A2Y9G9N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

29088:APLP2
gene id: 29088:APLP2
uniprot id: A0A2Y9HS01
uniprot id: A0A8M1MQD8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:PRL
gene id: 29088:PRL
uniprot id: A0A2Y9HLY9
uniprot id: A0A2Y9HM73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

29088:SNED1
gene id: 29088:SNED1
uniprot id: A0A8M1M6S8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ARSG
gene id: 29088:ARSG
uniprot id: A0A2Y9G8W2
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

29088:LOC110589708
gene id: 29088:LOC110589708
uniprot id: A0A8M1MF33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Homodimer. Interacts with CSTF2.
messages: Nucleus

29088:SMARCA5
gene id: 29088:SMARCA5
uniprot id: A0A2Y9G7S7
uniprot id: A0A8M1MCM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

29088:MMP17
gene id: 29088:MMP17
uniprot id: A0A2Y9HMQ7
names: Similarity
messages: Belongs to the peptidase M10A family.

29088:LOC110575799
gene id: 29088:LOC110575799
uniprot id: A0A2Y9GMZ5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:BUD31
gene id: 29088:BUD31
uniprot id: A0A2Y9GA59
uniprot id: A0A2Y9GCU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

29088:BAX
gene id: 29088:BAX
uniprot id: A0A2Y9GD30
uniprot id: A0A2Y9GD45
uniprot id: A0A8M1MW01
uniprot id: A0A8M1MW07
uniprot id: A0A8M1MXC4
uniprot id: A0A8M1MZF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

29088:LOC110570121
gene id: 29088:LOC110570121
uniprot id: A0A2Y9G3Z4
uniprot id: A0A2Y9G421
uniprot id: A0A2Y9G425
uniprot id: A0A2Y9G4G9
uniprot id: A0A2Y9G6I8
uniprot id: A0A2Y9G7N1
uniprot id: A0A8M1MXH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Cell membrane
messages: Cell surface
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Endoplasmic reticulum
messages: Endosome
messages: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis.
messages: Golgi apparatus
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).
messages: Nucleus
messages: Perikaryon
messages: Secreted
messages: The gamma-CTF peptides as well as the caspase-cleaved peptides, including C31, are potent enhancers of neuronal apoptosis.
messages: Vesicle
messages: clathrin-coated pit
messages: growth cone

29088:PFDN2
gene id: 29088:PFDN2
uniprot id: A0A2Y9GEN4
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

29088:STXBP3
gene id: 29088:STXBP3
uniprot id: A0A2Y9H2D3
uniprot id: A0A2Y9H2F1
uniprot id: A0A2Y9H2G2
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

29088:ZMYND10
gene id: 29088:ZMYND10
uniprot id: A0A2Y9GZP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ZMYND10 family.
messages: Dynein axonemal particle
messages: Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins.
messages: centriolar satellite

29088:PHKB
gene id: 29088:PHKB
uniprot id: A0A2Y9IBY8
uniprot id: A0A2Y9ICU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.

29088:CCBE1
gene id: 29088:CCBE1
uniprot id: A0A2Y9GS06
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LRP12
gene id: 29088:LRP12
uniprot id: A0A2Y9GXQ1
uniprot id: A0A8M1MCD8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ABLIM3
gene id: 29088:ABLIM3
uniprot id: A0A2Y9I496
uniprot id: A0A8M1MGX4
names: Subcellular Location Annotation
messages: Cytoplasm

29088:DIPK2A
gene id: 29088:DIPK2A
uniprot id: A0A2Y9G9S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

29088:PDE10A
gene id: 29088:PDE10A
uniprot id: A0A2Y9HHL0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

29088:UBE2E1
gene id: 29088:UBE2E1
uniprot id: A0A2Y9G9X8
uniprot id: A0A8M1MRM7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:NANOS3
gene id: 29088:NANOS3
uniprot id: A0A2Y9IB04
names: Similarity
messages: Belongs to the nanos family.

29088:MERTK
gene id: 29088:MERTK
uniprot id: A0A2Y9HUM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

29088:KCNMB4
gene id: 29088:KCNMB4
uniprot id: A0A2Y9G5W4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

29088:EMC4
gene id: 29088:EMC4
uniprot id: A0A2Y9HIG1
uniprot id: A0A2Y9HPQ0
uniprot id: A0A8M1MSQ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC4 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:SLC7A14
gene id: 29088:SLC7A14
uniprot id: A0A2Y9I2Y1
names: Subcellular Location Annotation
messages: Membrane

29088:DGKK
gene id: 29088:DGKK
uniprot id: A0A8M1M5M2
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

29088:C1H19orf25
gene id: 29088:C1H19orf25
uniprot id: A0A2Y9IAQ4
uniprot id: A0A2Y9IHY9
names: Similarity
messages: Belongs to the UPF0449 family.

29088:KIDINS220
gene id: 29088:KIDINS220
uniprot id: A0A2Y9HP21
uniprot id: A0A8M1MM33
uniprot id: A0A8M1MM34
uniprot id: A0A8M1MP28
uniprot id: A0A8M1MQD6
uniprot id: A0A8M1MWB1
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

29088:ACTRT2
gene id: 29088:ACTRT2
uniprot id: A0A2Y9GNZ3
names: Similarity
messages: Belongs to the actin family.

29088:ZSCAN1
gene id: 29088:ZSCAN1
uniprot id: A0A8M1M2R9
names: Subcellular Location Annotation
messages: Nucleus

29088:KIF12
gene id: 29088:KIF12
uniprot id: A0A2Y9HD38
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:DEFB132
gene id: 29088:DEFB132
uniprot id: A0A2Y9H4V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

29088:ELP5
gene id: 29088:ELP5
uniprot id: A0A2Y9HEP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP5 family.
messages: Cytoplasm
messages: Nucleus

29088:USP10
gene id: 29088:USP10
uniprot id: A0A2Y9IBJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP10 subfamily.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Nucleus

29088:MYO16
gene id: 29088:MYO16
uniprot id: A0A8M1M8C3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

29088:POLM
gene id: 29088:POLM
uniprot id: A0A2Y9I5U7
uniprot id: A0A2Y9I661
uniprot id: A0A2Y9I6N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ).
messages: Nucleus

29088:CDC20B
gene id: 29088:CDC20B
uniprot id: A0A2Y9I8G6
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

29088:MCTP2
gene id: 29088:MCTP2
uniprot id: A0A2Y9GBB9
uniprot id: A0A2Y9GE48
uniprot id: A0A2Y9GFN6
names: Subcellular Location Annotation
messages: Membrane

29088:NFX1
gene id: 29088:NFX1
uniprot id: A0A8M1MSA1
uniprot id: A0A8M1MVH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

29088:LOC110576451
gene id: 29088:LOC110576451
uniprot id: A0A2Y9GQ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110574488
gene id: 29088:LOC110574488
uniprot id: A0A2Y9GNF8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:PITX1
gene id: 29088:PITX1
uniprot id: A0A2Y9I1L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

29088:BRMS1
gene id: 29088:BRMS1
uniprot id: A0A2Y9GNB4
uniprot id: A0A2Y9GNF1
uniprot id: A0A2Y9GNN2
uniprot id: A0A2Y9GU29
names: Subcellular Location Annotation
messages: Nucleus

29088:C4BPA
gene id: 29088:C4BPA
uniprot id: A0A8M1MHF0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:CAP1
gene id: 29088:CAP1
uniprot id: A0A2Y9GL47
uniprot id: A0A2Y9GPX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CAP family.
messages: Cell membrane
messages: Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity.
messages: Homodimer. Binds actin monomers.
messages: Membrane

29088:SMCO2
gene id: 29088:SMCO2
uniprot id: A0A2Y9H8H2
names: Subcellular Location Annotation
messages: Membrane

29088:PSMG1
gene id: 29088:PSMG1
uniprot id: A0A2Y9G739
uniprot id: A0A2Y9G748
uniprot id: A0A8M1M8I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PSMG1 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2.
messages: Cytoplasm
messages: Forms a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer interacts directly with the PSMA5 and PSMA7 proteasome alpha subunits.
messages: Forms a heterodimer with psmg2.

29088:RPRD1A
gene id: 29088:RPRD1A
uniprot id: A0A2Y9GRF5
uniprot id: A0A8M1MYV8
names: Function
names: Similarity
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD.

29088:LOC110579492
gene id: 29088:LOC110579492
uniprot id: A0A2Y9GZZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prion family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane

29088:LOC110586172
gene id: 29088:LOC110586172
uniprot id: A0A8M1MX67
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110575803
gene id: 29088:LOC110575803
uniprot id: A0A2Y9GMS0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:C1H19orf53
gene id: 29088:C1H19orf53
uniprot id: A0A2Y9IAM0
names: Function
names: Similarity
messages: Belongs to the UPF0390 family.
messages: May have a potential role in hypercalcemia of malignancy.

29088:RLN3
gene id: 29088:RLN3
uniprot id: A0A2Y9IAB3
uniprot id: A0A8M1MAU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

29088:ADGRG2
gene id: 29088:ADGRG2
uniprot id: A0A2Y9GJR6
uniprot id: A0A2Y9GJT1
uniprot id: A0A2Y9GJU7
uniprot id: A0A2Y9GJX6
uniprot id: A0A2Y9GK31
uniprot id: A0A2Y9GN88
uniprot id: A0A2Y9GPZ5
uniprot id: A0A2Y9GQ14
uniprot id: A0A2Y9GQ29
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110569926
gene id: 29088:LOC110569926
uniprot id: A0A8M1MRU1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

29088:TMEM87B
gene id: 29088:TMEM87B
uniprot id: A0A2Y9HN13
uniprot id: A0A2Y9HUP6
uniprot id: A0A8M1MPD9
uniprot id: A0A8M1MV83
names: Subcellular Location Annotation
messages: Membrane

29088:ROM1
gene id: 29088:ROM1
uniprot id: A0A2Y9GPR3
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

29088:LOC110591829
gene id: 29088:LOC110591829
uniprot id: A0A8M1ME36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Secreted

29088:WASF2
gene id: 29088:WASF2
uniprot id: A0A2Y9GKU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

29088:LAMB4
gene id: 29088:LAMB4
uniprot id: A0A2Y9GKX0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

29088:LOC110581820
gene id: 29088:LOC110581820
uniprot id: A0A2Y9H6T7
uniprot id: A0A2Y9HCE2
names: Similarity
messages: Belongs to the AAA ATPase family.

29088:NUP85
gene id: 29088:NUP85
uniprot id: A0A2Y9GCH5
uniprot id: A0A8M1MX55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: nuclear pore complex

29088:PTGES2
gene id: 29088:PTGES2
uniprot id: A0A2Y9H5S7
uniprot id: A0A2Y9HCJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily.
messages: Membrane

29088:TRADD
gene id: 29088:TRADD
uniprot id: A0A2Y9I7E9
uniprot id: A0A2Y9IBF3
names: Subcellular Location Annotation
messages: Nucleus
messages: cytoskeleton

29088:SPTAN1
gene id: 29088:SPTAN1
uniprot id: A0A2Y9H6N8
uniprot id: A0A2Y9H6N9
uniprot id: A0A2Y9H6P3
uniprot id: A0A2Y9H6T5
uniprot id: A0A2Y9H6U0
uniprot id: A0A2Y9HC89
uniprot id: A0A8M1MRW5
uniprot id: A0A8M1MRX7
uniprot id: A0A8M1MV54
uniprot id: A0A8M1MYL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spectrin family.
messages: cell cortex
messages: cytoskeleton

29088:MCU
gene id: 29088:MCU
uniprot id: A0A8M1MII3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

29088:CDKN3
gene id: 29088:CDKN3
uniprot id: A0A2Y9I6H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family.
messages: May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.
messages: perinuclear region

29088:PLPPR3
gene id: 29088:PLPPR3
uniprot id: A0A2Y9IF84
uniprot id: A0A2Y9II75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

29088:PYGL
gene id: 29088:PYGL
uniprot id: A0A2Y9HZ81
uniprot id: A0A2Y9HZF1
uniprot id: A0A8M1MJ50
uniprot id: A0A8M1MMH3
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

29088:EPB41L5
gene id: 29088:EPB41L5
uniprot id: A0A2Y9HIN1
uniprot id: A0A8M1MEV6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Photoreceptor inner segment
messages: Plays a role in the formation and organization of tight junctions during the establishment of polarity in epithelial cells.

29088:SPEN
gene id: 29088:SPEN
uniprot id: A0A2Y9GKN9
names: Similarity
messages: Belongs to the RRM Spen family.

29088:LOC110574532
gene id: 29088:LOC110574532
uniprot id: A0A2Y9GII0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TBCA
gene id: 29088:TBCA
uniprot id: A0A2Y9I204
uniprot id: A0A8M1MJ58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
messages: cytoskeleton

29088:TAS2R60
gene id: 29088:TAS2R60
uniprot id: A0A2Y9HGK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

29088:HCN4
gene id: 29088:HCN4
uniprot id: A0A2Y9HD37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

29088:KCNH2
gene id: 29088:KCNH2
uniprot id: A0A8M1MT21
uniprot id: A0A8M1MY32
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110571792
gene id: 29088:LOC110571792
uniprot id: A0A2Y9G9J7
uniprot id: A0A2Y9G9K3
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

29088:CPLX4
gene id: 29088:CPLX4
uniprot id: A0A2Y9GS42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

29088:LOC110578447
gene id: 29088:LOC110578447
uniprot id: A0A2Y9H0S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:DNAH1
gene id: 29088:DNAH1
uniprot id: A0A2Y9HG24
names: Similarity
messages: Belongs to the dynein heavy chain family.

29088:LPAR4
gene id: 29088:LPAR4
uniprot id: A0A2Y9GYI3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:OLR1
gene id: 29088:OLR1
uniprot id: A0A2Y9H3Y5
names: Subcellular Location Annotation
messages: Membrane

29088:TMEM168
gene id: 29088:TMEM168
uniprot id: A0A2Y9HTC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM168 family.
messages: Membrane

29088:VPS13B
gene id: 29088:VPS13B
uniprot id: A0A2Y9GYQ3
uniprot id: A0A2Y9GYR5
names: Similarity
messages: Belongs to the VPS13 family.

29088:AKT1
gene id: 29088:AKT1
uniprot id: A0A2Y9GCY3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

29088:RHBDD3
gene id: 29088:RHBDD3
uniprot id: A0A2Y9ICV4
uniprot id: A0A8M1MYW7
names: Subcellular Location Annotation
messages: Membrane

29088:SHROOM1
gene id: 29088:SHROOM1
uniprot id: A0A2Y9I697
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

29088:OPN5
gene id: 29088:OPN5
uniprot id: A0A2Y9H826
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

29088:OSBPL5
gene id: 29088:OSBPL5
uniprot id: A0A8M1MQM7
names: Similarity
messages: Belongs to the OSBP family.

29088:PRUNE1
gene id: 29088:PRUNE1
uniprot id: A0A2Y9GWY3
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

29088:RABAC1
gene id: 29088:RABAC1
uniprot id: A0A2Y9H8E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

29088:LOC110587395
gene id: 29088:LOC110587395
uniprot id: A0A8M1MLT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

29088:LOC110587126
gene id: 29088:LOC110587126
uniprot id: A0A2Y9HUB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

29088:PAQR6
gene id: 29088:PAQR6
uniprot id: A0A2Y9GFA9
uniprot id: A0A2Y9GFB6
uniprot id: A0A2Y9GJZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

29088:ARMCX3
gene id: 29088:ARMCX3
uniprot id: A0A2Y9HM19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eutherian X-chromosome-specific Armcx family.
messages: Membrane

29088:LOC110573353
gene id: 29088:LOC110573353
uniprot id: A0A2Y9GEK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SLC25A32
gene id: 29088:SLC25A32
uniprot id: A0A2Y9GXM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:NIF3L1
gene id: 29088:NIF3L1
uniprot id: A0A2Y9IB40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Cytoplasm
messages: Homodimer. Interacts with COPS2. Interacts with THOC7.
messages: May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
messages: Nucleus

29088:CCDC86
gene id: 29088:CCDC86
uniprot id: A0A2Y9GMX8
names: Subcellular Location Annotation
messages: Nucleus

29088:S1PR2
gene id: 29088:S1PR2
uniprot id: A0A2Y9IHM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

29088:POLD3
gene id: 29088:POLD3
uniprot id: A0A2Y9ID95
names: Subcellular Location Annotation
messages: Nucleus

29088:RRAGB
gene id: 29088:RRAGB
uniprot id: A0A2Y9HZM8
uniprot id: A0A2Y9I3S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

29088:DES
gene id: 29088:DES
uniprot id: A0A2Y9IAG5
uniprot id: A0A8M1M753
uniprot id: A0A8M1M7E2
uniprot id: A0A8M1M9K0
uniprot id: A0A8M1MAY4
uniprot id: A0A8M1MFF3
names: Similarity
messages: Belongs to the intermediate filament family.

29088:SLC13A4
gene id: 29088:SLC13A4
uniprot id: A0A2Y9HAB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

29088:SNW1
gene id: 29088:SNW1
uniprot id: A0A2Y9G8L6
uniprot id: A0A2Y9GBY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNW family.
messages: Identified in the spliceosome C complex.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

29088:LOC110570609
gene id: 29088:LOC110570609
uniprot id: A0A8M1M1I4
names: Similarity
messages: Belongs to the NDK family.

29088:CRMP1
gene id: 29088:CRMP1
uniprot id: A0A2Y9G598
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

29088:UHRF1
gene id: 29088:UHRF1
uniprot id: A0A2Y9IHU4
uniprot id: A0A8M1MP06
names: Subcellular Location Annotation
messages: Nucleus

29088:RAB38
gene id: 29088:RAB38
uniprot id: A0A2Y9H799
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

29088:TMEM263
gene id: 29088:TMEM263
uniprot id: A0A2Y9GVL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

29088:ADAMTS16
gene id: 29088:ADAMTS16
uniprot id: A0A2Y9I2M5
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:LOC110584085
gene id: 29088:LOC110584085
uniprot id: A0A2Y9HDU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

29088:LOC110585646
gene id: 29088:LOC110585646
uniprot id: A0A8M1M927
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Cell membrane
messages: Chromosome
messages: Endoplasmic reticulum-Golgi intermediate compartment
messages: Secreted

29088:STAG2
gene id: 29088:STAG2
uniprot id: A0A2Y9GSL7
uniprot id: A0A2Y9GSS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

29088:PDE1C
gene id: 29088:PDE1C
uniprot id: A0A2Y9H143
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

29088:MVK
gene id: 29088:MVK
uniprot id: A0A2Y9IA08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
messages: Cytoplasm

29088:TNFSF8
gene id: 29088:TNFSF8
uniprot id: A0A2Y9HC73
names: Similarity
messages: Belongs to the tumor necrosis factor family.

29088:LOC110591828
gene id: 29088:LOC110591828
uniprot id: A0A8M1M9S6
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

29088:APC
gene id: 29088:APC
uniprot id: A0A8M1MGQ8
uniprot id: A0A8M1MIT6
uniprot id: A0A8M1MK48
uniprot id: A0A8M1MQK5
names: Similarity
messages: Belongs to the adenomatous polyposis coli (APC) family.

29088:KIF5C
gene id: 29088:KIF5C
uniprot id: A0A2Y9IB92
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:LOC110575338
gene id: 29088:LOC110575338
uniprot id: A0A2Y9GLD2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

29088:CTNND1
gene id: 29088:CTNND1
uniprot id: A0A2Y9GPJ3
uniprot id: A0A8M1MNH3
uniprot id: A0A8M1MQF4
names: Similarity
messages: Belongs to the beta-catenin family.

29088:RPL23A
gene id: 29088:RPL23A
uniprot id: A0A2Y9HIH4
uniprot id: A0A8M1MV35
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

29088:LOC110580212
gene id: 29088:LOC110580212
uniprot id: A0A2Y9H8D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

29088:OSBPL10
gene id: 29088:OSBPL10
uniprot id: A0A2Y9G8L8
uniprot id: A0A2Y9G9P0
names: Similarity
messages: Belongs to the OSBP family.

29088:UCMA
gene id: 29088:UCMA
uniprot id: A0A2Y9HL46
uniprot id: A0A2Y9HLB7
uniprot id: A0A2Y9HRS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UCMA family.
messages: May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.
messages: extracellular matrix

29088:SLC30A9
gene id: 29088:SLC30A9
uniprot id: A0A2Y9I0E2
uniprot id: A0A2Y9I6T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum
messages: Membrane
messages: Nucleus
messages: Vesicle

29088:VDAC3
gene id: 29088:VDAC3
uniprot id: A0A2Y9GDU7
uniprot id: A0A2Y9GDX2
uniprot id: A0A8M1M399
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.
messages: Interacts with ARMC12 in a TBC1D21-dependent manner.
messages: Mitochondrion outer membrane

29088:TNFRSF14
gene id: 29088:TNFRSF14
uniprot id: A0A2Y9GIP5
uniprot id: A0A2Y9GIZ6
uniprot id: A0A2Y9GNY6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ANP32A
gene id: 29088:ANP32A
uniprot id: A0A2Y9HCG0
uniprot id: A0A2Y9HCL3
uniprot id: A0A2Y9HCS9
uniprot id: A0A8M1MM57
names: Similarity
messages: Belongs to the ANP32 family.

29088:LOC110586089
gene id: 29088:LOC110586089
uniprot id: A0A2Y9HQE3
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110582689
gene id: 29088:LOC110582689
uniprot id: A0A2Y9H9F8
names: Function
names: Subunit
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

29088:HPGD
gene id: 29088:HPGD
uniprot id: A0A2Y9HZ23
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:LOC110572167
gene id: 29088:LOC110572167
uniprot id: A0A8M1MMR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

29088:PDRG1
gene id: 29088:PDRG1
uniprot id: A0A2Y9GZS4
uniprot id: A0A2Y9H664
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.
messages: Cytoplasm
messages: May play a role in chaperone-mediated protein folding.

29088:PEX3
gene id: 29088:PEX3
uniprot id: A0A2Y9HAP9
uniprot id: A0A8M1MRA5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PEX19.
messages: Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
messages: Peroxisome membrane

29088:ANAPC5
gene id: 29088:ANAPC5
uniprot id: A0A2Y9HWV7
uniprot id: A0A2Y9HYE7
uniprot id: A0A8M1MTL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC5 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: spindle

29088:SMIM12
gene id: 29088:SMIM12
uniprot id: A0A2Y9GN57
names: Similarity
messages: Belongs to the SMIM12 family.

29088:NUCB1
gene id: 29088:NUCB1
uniprot id: A0A2Y9GGA6
uniprot id: A0A2Y9GHR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobindin family.
messages: Cytoplasm
messages: Secreted
messages: cis-Golgi network membrane

29088:RAB32
gene id: 29088:RAB32
uniprot id: A0A2Y9HBF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

29088:ACMSD
gene id: 29088:ACMSD
uniprot id: A0A2Y9HIE1
uniprot id: A0A2Y9HPG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
messages: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
messages: Monomer.

29088:KLC4
gene id: 29088:KLC4
uniprot id: A0A2Y9H7A6
uniprot id: A0A8M1MK53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

29088:APOA5
gene id: 29088:APOA5
uniprot id: A0A7F3SAB1
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

29088:NUDT21
gene id: 29088:NUDT21
uniprot id: A0A2Y9ID21
uniprot id: A0A8M1MVT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

29088:LOC110582916
gene id: 29088:LOC110582916
uniprot id: A0A2Y9HAF0
names: Similarity
messages: Belongs to the TCAF family.

29088:LRRFIP2
gene id: 29088:LRRFIP2
uniprot id: A0A2Y9G2D4
uniprot id: A0A2Y9G2J1
uniprot id: A0A2Y9G2Z0
names: Similarity
messages: Belongs to the LRRFIP family.

29088:SPATA6L
gene id: 29088:SPATA6L
uniprot id: A0A2Y9HE25
uniprot id: A0A8M1MT12
uniprot id: A0A8M1MYG4
names: Similarity
messages: Belongs to the SPATA6 family.

29088:PIK3R2
gene id: 29088:PIK3R2
uniprot id: A0A2Y9GIG2
uniprot id: A0A2Y9GIN4
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

29088:CASD1
gene id: 29088:CASD1
uniprot id: A0A8M1MY26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PC-esterase family. CASD1 subfamily.
messages: Membrane

29088:LOC110593467
gene id: 29088:LOC110593467
uniprot id: A0A8M1MP99
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the splicing factor SR family.
messages: Found in mRNA splicing-dependent exon junction complexes (EJC). Found in a post-splicing complex with NXF1, RBM8A, UPF1, UPF2, UPF3A, UPF3B and RNPS1. Component of the heterotrimeric ASAP (apoptosis- and splicing-associated protein) and PSAP complexes consisting of RNPS1, SAP18 and either ACIN1 or PNN, respectively; the ASAP and PSAP complexes probably are formed mutually exclusive. Component of the active spliceosome. Associates with polysomes. Interacts with the cleaved p110 isoform of CDC2L1, CSNK2A1, PNN, SART3, SRP54, SRRM1 and TRA2B/SFRS10.
messages: Nucleus speckle

29088:TBC1D7
gene id: 29088:TBC1D7
uniprot id: A0A8M1MJK0
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Vesicle

29088:CDC37
gene id: 29088:CDC37
uniprot id: A0A2Y9I9M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

29088:ZNF592
gene id: 29088:ZNF592
uniprot id: A0A2Y9GDW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: May be involved in transcriptional regulation.
messages: Nucleus

29088:LOC110584712
gene id: 29088:LOC110584712
uniprot id: A0A8M1MZ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

29088:NPR2
gene id: 29088:NPR2
uniprot id: A0A2Y9HCK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

29088:AATF
gene id: 29088:AATF
uniprot id: A0A2Y9I8A5
uniprot id: A0A2Y9I909
names: Similarity
messages: Belongs to the AATF family.

29088:CENPA
gene id: 29088:CENPA
uniprot id: A0A2Y9HNL3
names: Similarity
messages: Belongs to the histone H3 family.

29088:SLC25A13
gene id: 29088:SLC25A13
uniprot id: A0A2Y9H1N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

29088:LOC110578497
gene id: 29088:LOC110578497
uniprot id: A0A2Y9GWU8
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

29088:PKNOX1
gene id: 29088:PKNOX1
uniprot id: A0A8M1M678
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

29088:LOC110590156
gene id: 29088:LOC110590156
uniprot id: A0A2Y9HY15
uniprot id: A0A2Y9HYC9
uniprot id: A0A8M1M344
uniprot id: A0A8M1M8B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TYROBP family.
messages: Cell membrane
messages: Membrane

29088:TAPT1
gene id: 29088:TAPT1
uniprot id: A0A8M1M6S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

29088:F7
gene id: 29088:F7
uniprot id: A0A8M1M5C0
uniprot id: A0A8M1M5N0
uniprot id: A0A8M1M7S2
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Heterodimer of a light chain and a heavy chain linked by a disulfide bond.
messages: Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:SORBS2
gene id: 29088:SORBS2
uniprot id: A0A2Y9HDT3
uniprot id: A0A2Y9HDT9
uniprot id: A0A2Y9HDY0
uniprot id: A0A2Y9HE61
uniprot id: A0A2Y9HE66
uniprot id: A0A2Y9HK14
uniprot id: A0A2Y9HKD2
uniprot id: A0A8M1M4F6
uniprot id: A0A8M1M4G1
uniprot id: A0A8M1M4Q5
uniprot id: A0A8M1M4R1
uniprot id: A0A8M1M6V9
uniprot id: A0A8M1M6W4
uniprot id: A0A8M1M8C5
uniprot id: A0A8M1M8C9
uniprot id: A0A8M1MCF2
uniprot id: A0A8M1MCF7
names: Subcellular Location Annotation
messages: focal adhesion

29088:TRHR
gene id: 29088:TRHR
uniprot id: A0A2Y9H4S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

29088:RAB29
gene id: 29088:RAB29
uniprot id: A0A2Y9GWS9
uniprot id: A0A2Y9GYD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

29088:DIS3L
gene id: 29088:DIS3L
uniprot id: A0A2Y9HCY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNR ribonuclease family.
messages: Component of the RNA exosome complex. The catalytically inactive RNA exosome core (Exo-9) complex is believed to associate with catalytic subunits EXOSC10, and DIS3 or DIS3L in cytoplasmic- and nuclear-specific RNA exosome complex forms.
messages: Cytoplasm
messages: Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.

29088:CTF1
gene id: 29088:CTF1
uniprot id: A0A8M1MEP8
uniprot id: A0A8M1MJJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

29088:DEFB112
gene id: 29088:DEFB112
uniprot id: A0A8M1MKH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

29088:RNASE12
gene id: 29088:RNASE12
uniprot id: A0A2Y9HNX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

29088:METTL6
gene id: 29088:METTL6
uniprot id: A0A2Y9G6D1
uniprot id: A0A2Y9G8T7
uniprot id: A0A8M1MYI6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

29088:ERBB3
gene id: 29088:ERBB3
uniprot id: A0A2Y9GYH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

29088:CSNK2B
gene id: 29088:CSNK2B
uniprot id: A0A2Y9HSK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.
messages: Tetramer of two alpha and two beta subunits.

29088:CACNG7
gene id: 29088:CACNG7
uniprot id: A0A2Y9GIX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2.

29088:AP2M1
gene id: 29088:AP2M1
uniprot id: A0A2Y9H9H1
uniprot id: A0A2Y9HFE9
uniprot id: A0A8M1MA12
uniprot id: A0A8M1MC57
uniprot id: A0A8M1MI81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cell membrane
messages: coated pit

29088:NQO2
gene id: 29088:NQO2
uniprot id: A0A2Y9HLN4
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

29088:PROK1
gene id: 29088:PROK1
uniprot id: A0A2Y9H9F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

29088:TERF2
gene id: 29088:TERF2
uniprot id: A0A2Y9I4S9
names: Subcellular Location Annotation
messages: telomere

29088:EDC3
gene id: 29088:EDC3
uniprot id: A0A2Y9HCR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

29088:ACAA1
gene id: 29088:ACAA1
uniprot id: A0A2Y9G2I2
uniprot id: A0A8M1MYM2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

29088:BABAM1
gene id: 29088:BABAM1
uniprot id: A0A2Y9GI43
uniprot id: A0A2Y9GI90
uniprot id: A0A2Y9GLH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BABAM1 family.
messages: Nucleus

29088:FAM189B
gene id: 29088:FAM189B
uniprot id: A0A2Y9GJN1
uniprot id: A0A8M1MEA8
uniprot id: A0A8M1MEE2
uniprot id: A0A8M1MEE7
uniprot id: A0A8M1MGG0
uniprot id: A0A8M1MHU8
uniprot id: A0A8M1MN16
names: Similarity
messages: Belongs to the ENTREP family.

29088:FOXN3
gene id: 29088:FOXN3
uniprot id: A0A2Y9GBM2
uniprot id: A0A2Y9GCL4
names: Subcellular Location Annotation
messages: Nucleus

29088:CDX2
gene id: 29088:CDX2
uniprot id: A0A2Y9G4I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

29088:ABCG5
gene id: 29088:ABCG5
uniprot id: A0A8M1MQH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

29088:CADM3
gene id: 29088:CADM3
uniprot id: A0A2Y9GEW1
uniprot id: A0A2Y9GEW4
uniprot id: A0A8M1MEG3
names: Similarity
messages: Belongs to the nectin family.

29088:LOC110584266
gene id: 29088:LOC110584266
uniprot id: A0A2Y9HKF8
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:BIRC2
gene id: 29088:BIRC2
uniprot id: A0A2Y9HR82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

29088:LOC123324891
gene id: 29088:LOC123324891
uniprot id: A0A8M1MD47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Nucleus
messages: P-body

29088:CADM4
gene id: 29088:CADM4
uniprot id: A0A2Y9GCL6
names: Similarity
messages: Belongs to the nectin family.

29088:MEAF6
gene id: 29088:MEAF6
uniprot id: A0A2Y9GJN3
uniprot id: A0A8M1M7R5
uniprot id: A0A8M1MA61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
messages: Component of the NuA4 histone acetyltransferase complex. Component of the hbo1 complex. Component of the moz/morf complex.
messages: kinetochore
messages: nucleolus

29088:LOC110577989
gene id: 29088:LOC110577989
uniprot id: A0A2Y9GVF2
names: Similarity
messages: Belongs to the methyltransferase superfamily.

29088:LOC110571790
gene id: 29088:LOC110571790
uniprot id: A0A8M1M873
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

29088:BTC
gene id: 29088:BTC
uniprot id: A0A2Y9I2N2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:TNNT1
gene id: 29088:TNNT1
uniprot id: A0A8M1MVR7
uniprot id: A0A8M1MVR9
uniprot id: A0A8M1MX73
uniprot id: A0A8M1MXW9
uniprot id: A0A8M1MXX0
uniprot id: A0A8M1MZD6
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

29088:LOC110576473
gene id: 29088:LOC110576473
uniprot id: A0A2Y9GVQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MASTL
gene id: 29088:MASTL
uniprot id: A0A2Y9GU59
uniprot id: A0A2Y9GUB5
uniprot id: A0A2Y9GUB6
uniprot id: A0A2Y9GYE9
uniprot id: A0A2Y9H038
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Nucleus
messages: centrosome

29088:LOC110576402
gene id: 29088:LOC110576402
uniprot id: A0A2Y9GVL3
names: Subcellular Location Annotation
messages: Membrane

29088:TELO2
gene id: 29088:TELO2
uniprot id: A0A2Y9HPX7
uniprot id: A0A2Y9HV69
names: Similarity
messages: Belongs to the TEL2 family.

29088:TPK1
gene id: 29088:TPK1
uniprot id: A0A2Y9H9M1
uniprot id: A0A2Y9H9T5
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

29088:TMPRSS9
gene id: 29088:TMPRSS9
uniprot id: A0A2Y9IA81
uniprot id: A0A8M1MVA5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:LOC110592684
gene id: 29088:LOC110592684
uniprot id: A0A8M1MSE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:EBNA1BP2
gene id: 29088:EBNA1BP2
uniprot id: A0A2Y9GK56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: Required for the processing of the 27S pre-rRNA.
messages: nucleolus

29088:GAPDH
gene id: 29088:GAPDH
uniprot id: A0A2Y9H9N9
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

29088:MINAR2
gene id: 29088:MINAR2
uniprot id: A0A2Y9I1J3
names: Similarity
messages: Belongs to the MINAR family.

29088:PTGDS
gene id: 29088:PTGDS
uniprot id: A0A2Y9H4W5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Membrane
messages: Monomer.
messages: Nucleus membrane
messages: Rough endoplasmic reticulum
messages: perinuclear region

29088:CXCL9
gene id: 29088:CXCL9
uniprot id: A0A2Y9I2W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

29088:LRP5
gene id: 29088:LRP5
uniprot id: A0A2Y9GP19
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:MRPL51
gene id: 29088:MRPL51
uniprot id: A0A2Y9H3Q8
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mL51 family.

29088:LOC110578153
gene id: 29088:LOC110578153
uniprot id: A0A8M1MD01
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

29088:ATP1B4
gene id: 29088:ATP1B4
uniprot id: A0A2Y9GR57
uniprot id: A0A2Y9GV80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

29088:PLK2
gene id: 29088:PLK2
uniprot id: A0A2Y9I290
uniprot id: A0A8M1MGZ9
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

29088:IER5
gene id: 29088:IER5
uniprot id: A0A2Y9GGG7
names: Similarity
messages: Belongs to the IER family.

29088:HSD17B10
gene id: 29088:HSD17B10
uniprot id: A0A2Y9HXN3
uniprot id: A0A2Y9HZD0
uniprot id: A0A8M1M0W3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:GALK1
gene id: 29088:GALK1
uniprot id: A0A2Y9HDU5
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

29088:LOC110586279
gene id: 29088:LOC110586279
uniprot id: A0A8M1MNS6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

29088:NUBP2
gene id: 29088:NUBP2
uniprot id: A0A2Y9HVC4
uniprot id: A0A2Y9HWW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. Interacts with KIFC1.
messages: Nucleus
messages: centrosome

29088:SLC4A11
gene id: 29088:SLC4A11
uniprot id: A0A2Y9GZA1
uniprot id: A0A8M1MKR1
uniprot id: A0A8M1MMR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

29088:ERN1
gene id: 29088:ERN1
uniprot id: A0A2Y9G8F7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:MTG1
gene id: 29088:MTG1
uniprot id: A0A2Y9HMI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Mitochondrion inner membrane
messages: Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays mitochondrial GTPase activity.

29088:RFTN1
gene id: 29088:RFTN1
uniprot id: A0A8M1MLC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

29088:MIS12
gene id: 29088:MIS12
uniprot id: A0A2Y9HEW4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mis12 family.
messages: Component of the MIS12 complex composed of MIS12, DSN1, NSL1 and PMF1. Also interacts with KNL1, CBX3, CBX5, NDC80 and ZWINT.
messages: kinetochore

29088:ADAMTS15
gene id: 29088:ADAMTS15
uniprot id: A0A2Y9HQZ0
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:UTP3
gene id: 29088:UTP3
uniprot id: A0A2Y9I1S3
names: Similarity
messages: Belongs to the SAS10 family.

29088:MAK16
gene id: 29088:MAK16
uniprot id: A0A2Y9HDI2
names: Similarity
messages: Belongs to the MAK16 family.

29088:LOC110585901
gene id: 29088:LOC110585901
uniprot id: A0A2Y9HJ83
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Phosphorylated by TGF-beta type II receptor.

29088:TENT5D
gene id: 29088:TENT5D
uniprot id: A0A2Y9H5Z1
names: Similarity
messages: Belongs to the TENT family.

29088:CDC25A
gene id: 29088:CDC25A
uniprot id: A0A8M1MH42
uniprot id: A0A8M1MR07
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

29088:LOC110572141
gene id: 29088:LOC110572141
uniprot id: A0A2Y9GEU7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

29088:BIVM
gene id: 29088:BIVM
uniprot id: A0A8M1M6Q5
names: Similarity
messages: Belongs to the BIVM family.

29088:CD34
gene id: 29088:CD34
uniprot id: A0A2Y9GJN4
uniprot id: A0A2Y9GLC8
names: Subcellular Location Annotation
messages: Membrane

29088:SAMD4B
gene id: 29088:SAMD4B
uniprot id: A0A8M1M0D4
uniprot id: A0A8M1M2Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

29088:MVD
gene id: 29088:MVD
uniprot id: A0A2Y9GY36
uniprot id: A0A2Y9GY48
uniprot id: A0A2Y9GYF1
names: Function
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.

29088:PRICKLE2
gene id: 29088:PRICKLE2
uniprot id: A0A2Y9HGV1
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

29088:LOC110581185
gene id: 29088:LOC110581185
uniprot id: A0A2Y9HA39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:KDM3B
gene id: 29088:KDM3B
uniprot id: A0A2Y9I0V3
names: Subcellular Location Annotation
messages: Nucleus

29088:DUSP3
gene id: 29088:DUSP3
uniprot id: A0A2Y9GE47
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

29088:IL15
gene id: 29088:IL15
uniprot id: A0A2Y9G7N8
uniprot id: A0A2Y9G7V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

29088:UBR1
gene id: 29088:UBR1
uniprot id: A0A2Y9HI55
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

29088:LOC110576151
gene id: 29088:LOC110576151
uniprot id: A0A2Y9GNT8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LSM1
gene id: 29088:LSM1
uniprot id: A0A2Y9GDU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: Interacts with SLBP; interaction with SLBP occurs when histone mRNA is being rapidly degraded during the S phase. LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.

29088:ACTG1
gene id: 29088:ACTG1
uniprot id: A0A2Y9GGH3
names: Similarity
messages: Belongs to the actin family.

29088:CHD9
gene id: 29088:CHD9
uniprot id: A0A8M1MWJ6
uniprot id: A0A8M1MXP1
uniprot id: A0A8M1MZJ4
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

29088:CDK14
gene id: 29088:CDK14
uniprot id: A0A2Y9H5X4
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:RFX1
gene id: 29088:RFX1
uniprot id: A0A8M1MIN3
names: Subcellular Location Annotation
messages: Nucleus

29088:BCLAF3
gene id: 29088:BCLAF3
uniprot id: A0A8M1M3Q8
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

29088:LOC110573430
gene id: 29088:LOC110573430
uniprot id: A0A2Y9GER4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:PUF60
gene id: 29088:PUF60
uniprot id: A0A2Y9GYS8
uniprot id: A0A2Y9GYT3
uniprot id: A0A2Y9GZ48
uniprot id: A0A2Y9GZ52
uniprot id: A0A2Y9H3F3
uniprot id: A0A2Y9H3F8
uniprot id: A0A2Y9H5F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM half pint family.
messages: Nucleus

29088:ACER3
gene id: 29088:ACER3
uniprot id: A0A2Y9I8W8
uniprot id: A0A2Y9I923
uniprot id: A0A2Y9I9I9
uniprot id: A0A2Y9IDF5
uniprot id: A0A8M1MSJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:EIF3B
gene id: 29088:EIF3B
uniprot id: A0A2Y9G9X7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Also interacts with UPF2. Interacts with METTL3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Cytoplasm
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: The RRM domain mediates interaction with EIF3J.

29088:HRK
gene id: 29088:HRK
uniprot id: A0A2Y9HRX6
names: Function
names: Subcellular Location Annotation
messages: Mitochondrion
messages: Promotes apoptosis.

29088:LOC110574371
gene id: 29088:LOC110574371
uniprot id: A0A2Y9GL89
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:GCSH
gene id: 29088:GCSH
uniprot id: A0A2Y9I3B9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

29088:SNAPIN
gene id: 29088:SNAPIN
uniprot id: A0A2Y9GFF4
names: Similarity
messages: Belongs to the SNAPIN family.

29088:MUC4
gene id: 29088:MUC4
uniprot id: A0A2Y9HG49
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ERG
gene id: 29088:ERG
uniprot id: A0A2Y9GAP4
uniprot id: A0A8M1M9Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

29088:RAD23B
gene id: 29088:RAD23B
uniprot id: A0A2Y9H5R1
uniprot id: A0A2Y9HB60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

29088:ERAP2
gene id: 29088:ERAP2
uniprot id: A0A2Y9HT12
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

29088:CRYBA4
gene id: 29088:CRYBA4
uniprot id: A0A2Y9I5F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

29088:TBCC
gene id: 29088:TBCC
uniprot id: A0A2Y9H807
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCC family.
messages: Cytoplasm
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.

29088:LOC110580104
gene id: 29088:LOC110580104
uniprot id: A0A8M1MQG0
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

29088:LOC110581454
gene id: 29088:LOC110581454
uniprot id: A0A2Y9H5P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

29088:CREG1
gene id: 29088:CREG1
uniprot id: A0A2Y9GGU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

29088:RAB27B
gene id: 29088:RAB27B
uniprot id: A0A2Y9GRJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

29088:LOC110576533
gene id: 29088:LOC110576533
uniprot id: A0A2Y9GQ98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:IDH1
gene id: 29088:IDH1
uniprot id: A0A2Y9I533
uniprot id: A0A2Y9I9B3
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

29088:LOC110575859
gene id: 29088:LOC110575859
uniprot id: A0A2Y9GMW6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:HAUS3
gene id: 29088:HAUS3
uniprot id: A0A2Y9G2R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS3 family.
messages: spindle

29088:PAXBP1
gene id: 29088:PAXBP1
uniprot id: A0A2Y9G412
uniprot id: A0A2Y9G6H4
names: Similarity
messages: Belongs to the GCF family.

29088:LOC110573139
gene id: 29088:LOC110573139
uniprot id: A0A2Y9GDZ2
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:TOP3A
gene id: 29088:TOP3A
uniprot id: A0A2Y9HEV5
uniprot id: A0A8M1MZ33
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

29088:PNOC
gene id: 29088:PNOC
uniprot id: A0A2Y9HSU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Secreted

29088:CHMP1A
gene id: 29088:CHMP1A
uniprot id: A0A2Y9I2G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF7 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

29088:GIMD1
gene id: 29088:GIMD1
uniprot id: A0A2Y9GLZ1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

29088:PUS7
gene id: 29088:PUS7
uniprot id: A0A2Y9GHH7
uniprot id: A0A8M1MRT1
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

29088:SLC37A2
gene id: 29088:SLC37A2
uniprot id: A0A2Y9HJH8
uniprot id: A0A2Y9HJV4
uniprot id: A0A2Y9HJW4
uniprot id: A0A2Y9HR88
uniprot id: A0A8M1MPN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.
messages: Membrane

29088:LOC110571986
gene id: 29088:LOC110571986
uniprot id: A0A2Y9GAA7
uniprot id: A0A8M1MGE6
uniprot id: A0A8M1MLF0
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. TRA1 subfamily.

29088:CREBL2
gene id: 29088:CREBL2
uniprot id: A0A2Y9H3R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

29088:SRD5A1
gene id: 29088:SRD5A1
uniprot id: A0A8M1MGG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

29088:HDAC4
gene id: 29088:HDAC4
uniprot id: A0A8M1M767
uniprot id: A0A8M1M7G1
uniprot id: A0A8M1M9M1
uniprot id: A0A8M1MB04
uniprot id: A0A8M1MFH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

29088:TXNRD1
gene id: 29088:TXNRD1
uniprot id: A0A2Y9GUW7
uniprot id: A0A2Y9GUX2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

29088:ZACN
gene id: 29088:ZACN
uniprot id: A0A2Y9GBU4
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110572213
gene id: 29088:LOC110572213
uniprot id: A0A8M1M5D5
names: Similarity
messages: Belongs to the translokin family.

29088:LOC110592292
gene id: 29088:LOC110592292
uniprot id: A0A8M1M604
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

29088:AIF1L
gene id: 29088:AIF1L
uniprot id: A0A2Y9HBM8
uniprot id: A0A8M1MRR2
names: Subcellular Location Annotation
messages: ruffle membrane

29088:FBLL1
gene id: 29088:FBLL1
uniprot id: A0A2Y9HQC9
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

29088:CHRNB3
gene id: 29088:CHRNB3
uniprot id: A0A2Y9GDW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:NHP2
gene id: 29088:NHP2
uniprot id: A0A2Y9I5V4
uniprot id: A0A8M1MG00
uniprot id: A0A8M1MG05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

29088:TEKT2
gene id: 29088:TEKT2
uniprot id: A0A2Y9GJN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

29088:EIF3E
gene id: 29088:EIF3E
uniprot id: A0A2Y9GYV7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with COPS3, COPS6, COPS7 (COPS7A or COPS7B), EIF4G1, EPAS1, MCM7, NCBP1, PSMC6, TRIM27 and UPF2.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Phosphorylated upon DNA damage, probably by ATM or ATR.

29088:LOC110578449
gene id: 29088:LOC110578449
uniprot id: A0A2Y9GWE2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110572383
gene id: 29088:LOC110572383
uniprot id: A0A2Y9GBD2
uniprot id: A0A8M1MIL6
uniprot id: A0A8M1MIM2
uniprot id: A0A8M1MKN6
uniprot id: A0A8M1MLZ7
uniprot id: A0A8M1MSL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

29088:LOC110587807
gene id: 29088:LOC110587807
uniprot id: A0A8M1MDP6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

29088:SEZ6L2
gene id: 29088:SEZ6L2
uniprot id: A0A2Y9HWT0
uniprot id: A0A2Y9HX00
uniprot id: A0A2Y9HX73
uniprot id: A0A2Y9I1V9
uniprot id: A0A2Y9I1W4
uniprot id: A0A2Y9I3K8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:NTRK3
gene id: 29088:NTRK3
uniprot id: A0A2Y9GAZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

29088:HOXA10
gene id: 29088:HOXA10
uniprot id: A0A2Y9H5T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

29088:CPXM1
gene id: 29088:CPXM1
uniprot id: A0A2Y9GZR4
uniprot id: A0A8M1MLM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

29088:OSBPL6
gene id: 29088:OSBPL6
uniprot id: A0A2Y9I377
uniprot id: A0A2Y9I3G1
uniprot id: A0A2Y9I3R5
uniprot id: A0A2Y9I816
uniprot id: A0A2Y9IA84
names: Similarity
messages: Belongs to the OSBP family.

29088:LOC110571720
gene id: 29088:LOC110571720
uniprot id: A0A2Y9G9C4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110583606
gene id: 29088:LOC110583606
uniprot id: A0A2Y9HBZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

29088:SRXN1
gene id: 29088:SRXN1
uniprot id: A0A2Y9GZT6
names: Similarity
messages: Belongs to the sulfiredoxin family.

29088:TP63
gene id: 29088:TP63
uniprot id: A0A2Y9H968
uniprot id: A0A2Y9H9B6
uniprot id: A0A2Y9HFU6
uniprot id: A0A2Y9HFV0
uniprot id: A0A8M1MPR8
uniprot id: A0A8M1MPT4
uniprot id: A0A8M1MT00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Binds DNA as a homotetramer. Isoform composition of the tetramer may determine transactivation activity.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Mitochondrion matrix
messages: Nucleus
messages: PML body
messages: centrosome

29088:FOXD1
gene id: 29088:FOXD1
uniprot id: A0A2Y9I160
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110586611
gene id: 29088:LOC110586611
uniprot id: A0A8M1MKP4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:LMNA
gene id: 29088:LMNA
uniprot id: A0A8M1MD68
uniprot id: A0A8M1MDB8
uniprot id: A0A8M1MGT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Nucleus lamina

29088:NDUFA11
gene id: 29088:NDUFA11
uniprot id: A0A2Y9IBF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA11 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:HCFC1
gene id: 29088:HCFC1
uniprot id: A0A8M1M571
uniprot id: A0A8M1M8Y1
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110570230
gene id: 29088:LOC110570230
uniprot id: A0A8M1M9H6
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.
messages: Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.

29088:TARS2
gene id: 29088:TARS2
uniprot id: A0A2Y9H109
uniprot id: A0A8M1MC21
uniprot id: A0A8M1MGM2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

29088:CAMKMT
gene id: 29088:CAMKMT
uniprot id: A0A2Y9I5M6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:MUSTN1
gene id: 29088:MUSTN1
uniprot id: A0A8M1M4D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUSTANG family.
messages: Nucleus

29088:SEMA4B
gene id: 29088:SEMA4B
uniprot id: A0A2Y9GBI3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SLC39A1
gene id: 29088:SLC39A1
uniprot id: A0A2Y9GEY3
names: Subcellular Location Annotation
messages: Membrane

29088:SLC7A6OS
gene id: 29088:SLC7A6OS
uniprot id: A0A2Y9I555
uniprot id: A0A2Y9I5W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWR1/SLC7A6OS family.
messages: Cytoplasm
messages: Directs RNA polymerase II nuclear import.
messages: Nucleus

29088:PNPLA5
gene id: 29088:PNPLA5
uniprot id: A0A2Y9GVX3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SLC30A3
gene id: 29088:SLC30A3
uniprot id: A0A2Y9HNB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

29088:SH3BP4
gene id: 29088:SH3BP4
uniprot id: A0A2Y9G6H5
names: Subcellular Location Annotation
messages: Nucleus
messages: Vesicle
messages: clathrin-coated pit
messages: clathrin-coated vesicle

29088:SLC6A3
gene id: 29088:SLC6A3
uniprot id: A0A8M1MQC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.
messages: Cell membrane
messages: Membrane
messages: axon
messages: neuron projection

29088:ACKR3
gene id: 29088:ACKR3
uniprot id: A0A2Y9G6I4
uniprot id: A0A2Y9G900
uniprot id: A0A2Y9GA28
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:NIPAL4
gene id: 29088:NIPAL4
uniprot id: A0A2Y9I5G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

29088:MUSK
gene id: 29088:MUSK
uniprot id: A0A2Y9H665
uniprot id: A0A2Y9H666
uniprot id: A0A2Y9HBN3
uniprot id: A0A8M1MRP7
uniprot id: A0A8M1MRQ6
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:VKORC1L1
gene id: 29088:VKORC1L1
uniprot id: A0A2Y9HWM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:RPP30
gene id: 29088:RPP30
uniprot id: A0A2Y9HZW2
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

29088:ARF6
gene id: 29088:ARF6
uniprot id: A0A2Y9I6D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Cell membrane
messages: Cleavage furrow
messages: Endosome membrane
messages: Midbody ring
messages: Recycling endosome membrane
messages: filopodium membrane
messages: ruffle

29088:FABP5
gene id: 29088:FABP5
uniprot id: A0A2Y9H3L7
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:ATP2A1
gene id: 29088:ATP2A1
uniprot id: A0A8M1MET4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

29088:SULF2
gene id: 29088:SULF2
uniprot id: A0A8M1MMW6
uniprot id: A0A8M1MV07
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin.
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

29088:ARG1
gene id: 29088:ARG1
uniprot id: A0A2Y9HC35
uniprot id: A0A8M1MLN0
uniprot id: A0A8M1MS88
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

29088:ADGRD1
gene id: 29088:ADGRD1
uniprot id: A0A2Y9HR73
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:FGF6
gene id: 29088:FGF6
uniprot id: A0A2Y9HAU1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

29088:BRIX1
gene id: 29088:BRIX1
uniprot id: A0A2Y9HQS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRX1 family.
messages: Required for biogenesis of the 60S ribosomal subunit.
messages: nucleolus

29088:PSD4
gene id: 29088:PSD4
uniprot id: A0A2Y9HMZ3
uniprot id: A0A2Y9HN60
uniprot id: A0A2Y9HNF1
uniprot id: A0A8M1MVI7
names: Subcellular Location Annotation
messages: ruffle membrane

29088:CIAO3
gene id: 29088:CIAO3
uniprot id: A0A2Y9HPG3
names: Similarity
messages: Belongs to the NARF family.

29088:LOC110586075
gene id: 29088:LOC110586075
uniprot id: A0A2Y9HR31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:STEAP3
gene id: 29088:STEAP3
uniprot id: A0A2Y9HPA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

29088:UPF2
gene id: 29088:UPF2
uniprot id: A0A2Y9HL29
uniprot id: A0A2Y9HSL9
names: Subcellular Location Annotation
messages: Cytoplasm

29088:MPP4
gene id: 29088:MPP4
uniprot id: A0A2Y9I4L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane

29088:MIF
gene id: 29088:MIF
uniprot id: A0A2Y9GWL6
names: Similarity
messages: Belongs to the MIF family.

29088:HSPA13
gene id: 29088:HSPA13
uniprot id: A0A2Y9G7Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Binds UBQLN2.
messages: Endoplasmic reticulum
messages: Has peptide-independent ATPase activity.
messages: Microsome

29088:PELP1
gene id: 29088:PELP1
uniprot id: A0A2Y9HLD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Cytoplasm
messages: Nucleus

29088:P4HB
gene id: 29088:P4HB
uniprot id: A0A2Y9GEW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

29088:ADAM9
gene id: 29088:ADAM9
uniprot id: A0A8M1M6U9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:HPSE2
gene id: 29088:HPSE2
uniprot id: A0A2Y9I259
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

29088:MRPS18C
gene id: 29088:MRPS18C
uniprot id: A0A2Y9I235
uniprot id: A0A2Y9I2L4
uniprot id: A0A8M1M801
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Mitochondrion

29088:ALOX15B
gene id: 29088:ALOX15B
uniprot id: A0A2Y9HLR0
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:GNAL
gene id: 29088:GNAL
uniprot id: A0A8M1MUR6
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

29088:LOC110592875
gene id: 29088:LOC110592875
uniprot id: A0A2Y9I788
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.

29088:LOC110576150
gene id: 29088:LOC110576150
uniprot id: A0A2Y9GSS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110574335
gene id: 29088:LOC110574335
uniprot id: A0A2Y9GHP5
names: Similarity
messages: Belongs to the AKAP110 family.

29088:TMEM80
gene id: 29088:TMEM80
uniprot id: A0A2Y9HDU9
names: Subcellular Location Annotation
messages: Membrane

29088:MACIR
gene id: 29088:MACIR
uniprot id: A0A2Y9HSR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UNC119-binding protein family.
messages: Cytoplasm
messages: cilium

29088:PDLIM1
gene id: 29088:PDLIM1
uniprot id: A0A2Y9I265
names: Subcellular Location Annotation
messages: Z line

29088:LOC110578665
gene id: 29088:LOC110578665
uniprot id: A0A8M1M0Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

29088:NINJ2
gene id: 29088:NINJ2
uniprot id: A0A2Y9H901
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

29088:LOC110589642
gene id: 29088:LOC110589642
uniprot id: A0A2Y9HVS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family. TFA subfamily.
messages: Nucleus

29088:MAN2C1
gene id: 29088:MAN2C1
uniprot id: A0A2Y9HCQ1
uniprot id: A0A2Y9HII6
uniprot id: A0A2Y9HJ03
uniprot id: A0A8M1MKM9
uniprot id: A0A8M1MMN9
uniprot id: A0A8M1MNZ6
uniprot id: A0A8M1MUS2
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

29088:OXSM
gene id: 29088:OXSM
uniprot id: A0A2Y9G8J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function.
messages: Mitochondrion

29088:LOC110591466
gene id: 29088:LOC110591466
uniprot id: A0A8M1M827
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:PKN1
gene id: 29088:PKN1
uniprot id: A0A2Y9IE34
uniprot id: A0A2Y9IGU6
uniprot id: A0A8M1MLX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Midbody
messages: Nucleus

29088:NIBAN2
gene id: 29088:NIBAN2
uniprot id: A0A2Y9H5D5
names: Similarity
messages: Belongs to the Niban family.

29088:LOC110576050
gene id: 29088:LOC110576050
uniprot id: A0A2Y9GNH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GST superfamily. Pi family.
messages: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Nucleus

29088:GPR55
gene id: 29088:GPR55
uniprot id: A0A2Y9H9S8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:PRPS1L1
gene id: 29088:PRPS1L1
uniprot id: A0A2Y9H1H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

29088:FAIM2
gene id: 29088:FAIM2
uniprot id: A0A2Y9I9S1
uniprot id: A0A2Y9IGF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

29088:RNF168
gene id: 29088:RNF168
uniprot id: A0A2Y9H8J8
uniprot id: A0A2Y9HEB0
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: According to a well-established model, RNF168 cannot initiate H2A 'Lys-63'-linked ubiquitination and is recruited following RNF8-dependent histone ubiquitination to amplify H2A 'Lys-63'-linked ubiquitination. However, other data suggest that RNF168 is the priming ubiquitin ligase by mediating monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub respectively). These data suggest that RNF168 might be recruited to DSBs sites in a RNF8-dependent manner by binding to non-histone proteins ubiquitinated via 'Lys-63'-linked and initiates monoubiquitination of H2A, which is then amplified by RNF8. Additional evidences are however required to confirm these data.
messages: Belongs to the RNF168 family.
messages: E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recruited at DNA interstrand cross-links (ICLs) sites and promotes accumulation of 'Lys-63'-linked ubiquitination of histones H2A and H2AX, leading to recruitment of FAAP20 and Fanconi anemia (FA) complex, followed by interstrand cross-link repair. H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Also involved in class switch recombination in immune system, via its role in regulation of DSBs repair. Following DNA damage, promotes the ubiquitination and degradation of JMJD2A/KDM4A in collaboration with RNF8, leading to unmask H4K20me2 mark and promote the recruitment of TP53BP1 at DNA damage sites. Not able to initiate 'Lys-63'-linked ubiquitination in vitro; possibly due to partial occlusion of the UBE2N/UBC13-binding region. Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with UBE2N/UBC13.
messages: Nucleus
messages: Sumoylated with SUMO1 by PIAS4 in response to double-strand breaks (DSBs).
messages: The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).
messages: Ubiquitinated.

29088:CLDN12
gene id: 29088:CLDN12
uniprot id: A0A2Y9H1G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Membrane
messages: tight junction

29088:SF3A2
gene id: 29088:SF3A2
uniprot id: A0A2Y9IEY3
names: Similarity
messages: Belongs to the SF3A2 family.

29088:LOC110571115
gene id: 29088:LOC110571115
uniprot id: A0A8M1M8T4
names: Subcellular Location Annotation
messages: Nucleus

29088:SLC44A3
gene id: 29088:SLC44A3
uniprot id: A0A2Y9H2B0
uniprot id: A0A8M1MAG1
uniprot id: A0A8M1MBU2
uniprot id: A0A8M1MGD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

29088:RBPJL
gene id: 29088:RBPJL
uniprot id: A0A2Y9GZE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

29088:LAMA5
gene id: 29088:LAMA5
uniprot id: A0A8M1MMB5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

29088:GPD1L
gene id: 29088:GPD1L
uniprot id: A0A2Y9G662
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

29088:CLCN7
gene id: 29088:CLCN7
uniprot id: A0A2Y9HPY2
uniprot id: A0A8M1MEK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

29088:GRM1
gene id: 29088:GRM1
uniprot id: A0A2Y9HBL8
uniprot id: A0A2Y9HBS4
uniprot id: A0A2Y9HI57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

29088:EID1
gene id: 29088:EID1
uniprot id: A0A2Y9HDL6
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110570676
gene id: 29088:LOC110570676
uniprot id: A0A2Y9G9F2
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:CUL5
gene id: 29088:CUL5
uniprot id: A0A2Y9HKL3
names: Similarity
messages: Belongs to the cullin family.

29088:APPL2
gene id: 29088:APPL2
uniprot id: A0A2Y9GUS1
uniprot id: A0A2Y9GUX6
uniprot id: A0A8M1MDY9
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Nucleus
messages: phagosome
messages: ruffle

29088:CNN2
gene id: 29088:CNN2
uniprot id: A0A2Y9IA26
uniprot id: A0A8M1MM09
uniprot id: A0A8M1MQE1
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

29088:DOK2
gene id: 29088:DOK2
uniprot id: A0A2Y9HS73
uniprot id: A0A2Y9HZ39
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

29088:TMEM200C
gene id: 29088:TMEM200C
uniprot id: A0A2Y9GX67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

29088:UBA2
gene id: 29088:UBA2
uniprot id: A0A2Y9I552
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.
messages: Nucleus
messages: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

29088:LOC110572171
gene id: 29088:LOC110572171
uniprot id: A0A8M1MNI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

29088:GFRA2
gene id: 29088:GFRA2
uniprot id: A0A2Y9HS03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.

29088:LPCAT2
gene id: 29088:LPCAT2
uniprot id: A0A8M1MW84
uniprot id: A0A8M1MY33
uniprot id: A0A8M1MZH1
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

29088:NLGN3
gene id: 29088:NLGN3
uniprot id: A0A2Y9GEZ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:TMEM59L
gene id: 29088:TMEM59L
uniprot id: A0A2Y9GI61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:TSR2
gene id: 29088:TSR2
uniprot id: A0A2Y9HU33
uniprot id: A0A8M1M2A0
names: Function
names: Similarity
messages: Belongs to the TSR2 family.
messages: May be involved in 20S pre-rRNA processing.

29088:EP400
gene id: 29088:EP400
uniprot id: A0A2Y9HML0
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110577419
gene id: 29088:LOC110577419
uniprot id: A0A2Y9GT29
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:AIDA
gene id: 29088:AIDA
uniprot id: A0A2Y9HVY0
names: Similarity
messages: Belongs to the AIDA family.

29088:LOC110579508
gene id: 29088:LOC110579508
uniprot id: A0A8M1MLR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Nucleus

29088:FUT11
gene id: 29088:FUT11
uniprot id: A0A2Y9I1U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Predominantly fucosylates the innermost N-acetyl glucosamine (GlcNAc) residue in biantennary N-glycan acceptors.

29088:CHIA
gene id: 29088:CHIA
uniprot id: A0A2Y9H2R6
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

29088:LOC110578539
gene id: 29088:LOC110578539
uniprot id: A0A8M1M885
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

29088:LOC110574484
gene id: 29088:LOC110574484
uniprot id: A0A8M1MIF8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

29088:SERPINI2
gene id: 29088:SERPINI2
uniprot id: A0A2Y9I9W8
names: Similarity
messages: Belongs to the serpin family.

29088:LOC110576866
gene id: 29088:LOC110576866
uniprot id: A0A2Y9GRC2
uniprot id: A0A2Y9GRF1
uniprot id: A0A8M1MYZ2
names: Subcellular Location Annotation
messages: Nucleus

29088:LBX2
gene id: 29088:LBX2
uniprot id: A0A2Y9HT21
names: Subcellular Location Annotation
messages: Nucleus

29088:DDX4
gene id: 29088:DDX4
uniprot id: A0A2Y9I163
uniprot id: A0A2Y9I5M7
uniprot id: A0A2Y9I7M4
names: Similarity
messages: Belongs to the DEAD box helicase family.

29088:MSRA
gene id: 29088:MSRA
uniprot id: A0A2Y9HS82
uniprot id: A0A8M1M4J1
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

29088:LOC110571536
gene id: 29088:LOC110571536
uniprot id: A0A2Y9GC46
names: Similarity
messages: Belongs to the serpin family.

29088:COMT
gene id: 29088:COMT
uniprot id: A0A2Y9H4F7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
messages: Cell membrane

29088:LOC123323402
gene id: 29088:LOC123323402
uniprot id: A0A8M1M5Q7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

29088:CGA
gene id: 29088:CGA
uniprot id: A0A2Y9HBI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Heterodimer. The active hormones thyrotropin, lutropin and follitropin are heterodimers composed of CGA, a common alpha chain described here and a unique beta chain which confers their biological specificity to the hormones: TSHB for thyrotropin, LHB for lutropin and FSHB for follitropin.
messages: Secreted
messages: Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.

29088:LOC110572128
gene id: 29088:LOC110572128
uniprot id: A0A8M1M505
names: Similarity
messages: Belongs to the TMA7 family.

29088:KCTD13
gene id: 29088:KCTD13
uniprot id: A0A2Y9I208
names: Similarity
messages: Belongs to the BACURD family.

29088:BCL2L13
gene id: 29088:BCL2L13
uniprot id: A0A2Y9H4D8
uniprot id: A0A8M1MAM0
names: Similarity
messages: Belongs to the Bcl-2 family.

29088:CLDN6
gene id: 29088:CLDN6
uniprot id: A0A2Y9HVM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

29088:LOC110591967
gene id: 29088:LOC110591967
uniprot id: A0A8M1M8A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:FREM2
gene id: 29088:FREM2
uniprot id: A0A2Y9G4N3
names: Similarity
messages: Belongs to the FRAS1 family.

29088:CPQ
gene id: 29088:CPQ
uniprot id: A0A2Y9H3U6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. The monomeric form is inactive while the homodimer is active.
messages: Lysosome
messages: Secreted

29088:ASXL1
gene id: 29088:ASXL1
uniprot id: A0A8M1MQJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asx family.
messages: Nucleus

29088:KCNK15
gene id: 29088:KCNK15
uniprot id: A0A2Y9H4L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

29088:SNRPD1
gene id: 29088:SNRPD1
uniprot id: A0A2Y9GXA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP core protein family.
messages: Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Most spliceosomal snRNPs contain a common set of Sm proteins, SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. Component of the U1 snRNP. The U1 snRNP is composed of the U1 snRNA and the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG, and at least three U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. Component of the U4/U6-U5 tri-snRNP complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, SNRNP40, SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, DDX23, CD2BP2, PPIH, SNU13, EFTUD2, SART1 and USP39, plus LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Part of the SMN-Sm complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8, STRAP/UNRIP and the Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG; catalyzes core snRNPs assembly. Forms a 6S pICln-Sm complex composed of CLNS1A/pICln, SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG; ring-like structure where CLNS1A/pICln mimics additional Sm proteins and which is unable to assemble into the core snRNP.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.
messages: cytosol

29088:ERO1A
gene id: 29088:ERO1A
uniprot id: A0A2Y9HZB2
uniprot id: A0A2Y9HZI6
uniprot id: A0A2Y9I4A9
uniprot id: A0A8M1MIP3
uniprot id: A0A8M1MIP7
uniprot id: A0A8M1MIP8
uniprot id: A0A8M1MKQ8
uniprot id: A0A8M1MKR2
uniprot id: A0A8M1MM20
uniprot id: A0A8M1MM25
uniprot id: A0A8M1MSN9
uniprot id: A0A8M1MSP4
uniprot id: A0A8M1MSP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

29088:PKP3
gene id: 29088:PKP3
uniprot id: A0A2Y9H873
uniprot id: A0A2Y9H8B6
names: Similarity
messages: Belongs to the beta-catenin family.

29088:OIP5
gene id: 29088:OIP5
uniprot id: A0A2Y9HHU0
uniprot id: A0A8M1MJU8
names: Function
names: Subcellular Location Annotation
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

29088:PSMB5
gene id: 29088:PSMB5
uniprot id: A0A2Y9HP60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB5 displays a chymotrypsin-like activity.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

29088:LOC110570363
gene id: 29088:LOC110570363
uniprot id: A0A2Y9G5A0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.

29088:ADA
gene id: 29088:ADA
uniprot id: A0A2Y9H498
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Cell junction
messages: Cell membrane
messages: Cytoplasmic vesicle lumen

29088:REEP4
gene id: 29088:REEP4
uniprot id: A0A2Y9HYS1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:NELFCD
gene id: 29088:NELFCD
uniprot id: A0A2Y9G3B0
uniprot id: A0A8M1MV27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NELF-D family.
messages: Nucleus

29088:LOC110580809
gene id: 29088:LOC110580809
uniprot id: A0A2Y9H8G3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

29088:KNG1
gene id: 29088:KNG1
uniprot id: A0A2Y9H9R1
uniprot id: A0A2Y9HFG4
uniprot id: A0A2Y9HGB3
names: Subcellular Location Annotation
messages: extracellular space

29088:LMOD3
gene id: 29088:LMOD3
uniprot id: A0A2Y9HGS3
names: Subcellular Location Annotation
messages: cytoskeleton

29088:MMUT
gene id: 29088:MMUT
uniprot id: A0A2Y9HCW3
names: Function
names: Similarity
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.

29088:DLGAP1
gene id: 29088:DLGAP1
uniprot id: A0A2Y9GRG7
uniprot id: A0A2Y9GRH3
uniprot id: A0A2Y9GRN1
uniprot id: A0A2Y9GRR2
uniprot id: A0A2Y9GVK1
uniprot id: A0A2Y9GX78
names: Similarity
messages: Belongs to the SAPAP family.

29088:FUT1
gene id: 29088:FUT1
uniprot id: A0A2Y9GCW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 11 family.
messages: Golgi stack membrane
messages: Membrane

29088:GTF2A2
gene id: 29088:GTF2A2
uniprot id: A0A2Y9HCT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.

29088:PIWIL4
gene id: 29088:PIWIL4
uniprot id: A0A2Y9G9A9
names: Similarity
messages: Belongs to the argonaute family.

29088:HOXD13
gene id: 29088:HOXD13
uniprot id: A0A2Y9I582
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

29088:PLCD1
gene id: 29088:PLCD1
uniprot id: A0A2Y9G2D0
uniprot id: A0A2Y9G2I6
uniprot id: A0A2Y9G2Y5
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

29088:CNTNAP5
gene id: 29088:CNTNAP5
uniprot id: A0A2Y9HIL7
uniprot id: A0A8M1M845
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.
messages: Membrane

29088:DPEP1
gene id: 29088:DPEP1
uniprot id: A0A2Y9I202
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Cell membrane
messages: Homodimer; disulfide-linked.
messages: Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver.
messages: Membrane

29088:PLD5
gene id: 29088:PLD5
uniprot id: A0A2Y9GHF8
names: Similarity
messages: Belongs to the phospholipase D family.

29088:TOMM40L
gene id: 29088:TOMM40L
uniprot id: A0A2Y9GER9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

29088:KCNN1
gene id: 29088:KCNN1
uniprot id: A0A8M1ML80
names: Subcellular Location Annotation
messages: Membrane

29088:DPYSL2
gene id: 29088:DPYSL2
uniprot id: A0A2Y9HZC4
uniprot id: A0A8M1MBP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Homotetramer, and heterotetramer with CRMP1, DPYSL3, DPYSL4 or DPYSL5. Interacts through its C-terminus with the C-terminus of CYFIP1/SRA1. Interacts with HTR4. Interacts with CLN6. Interacts with MICALL1.
messages: Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.

29088:LAD1
gene id: 29088:LAD1
uniprot id: A0A2Y9GK84
names: Function
names: Subcellular Location Annotation
messages: Anchoring filament protein which is a component of the basement membrane zone.
messages: basement membrane

29088:EXOC1
gene id: 29088:EXOC1
uniprot id: A0A2Y9I0A5
uniprot id: A0A2Y9I4T8
uniprot id: A0A2Y9I6P5
names: Similarity
messages: Belongs to the SEC3 family.

29088:CALHM2
gene id: 29088:CALHM2
uniprot id: A0A2Y9I1S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

29088:ARSB
gene id: 29088:ARSB
uniprot id: A0A2Y9HV07
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

29088:SUOX
gene id: 29088:SUOX
uniprot id: A0A2Y9GUE0
names: Function
messages: Catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of sulfur-containing amino acids.

29088:LOC110579982
gene id: 29088:LOC110579982
uniprot id: A0A2Y9H5X9
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:LOC110590450
gene id: 29088:LOC110590450
uniprot id: A0A8M1MNQ5
names: Similarity
messages: Belongs to the PRORSD1 family.

29088:LOC110570817
gene id: 29088:LOC110570817
uniprot id: A0A8M1MQY6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

29088:LOC110576447
gene id: 29088:LOC110576447
uniprot id: A0A2Y9GQ63
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:RNF20
gene id: 29088:RNF20
uniprot id: A0A2Y9H6V0
uniprot id: A0A2Y9H714
uniprot id: A0A8M1MU21
uniprot id: A0A8M1MYN7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BRE1 family.
messages: Component of the RNF20/40 complex (also known as BRE1 complex) probably composed of 2 copies of RNF20/BRE1A and 2 copies of RNF40/BRE1B. Interacts with UBE2E1/UBCH6.
messages: Nucleus

29088:LOC110579126
gene id: 29088:LOC110579126
uniprot id: A0A8M1MI46
names: Similarity
messages: Belongs to the GroES chaperonin family.

29088:RECQL4
gene id: 29088:RECQL4
uniprot id: A0A2Y9H2M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

29088:LOC110572244
gene id: 29088:LOC110572244
uniprot id: A0A2Y9GB19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:RGMA
gene id: 29088:RGMA
uniprot id: A0A2Y9GDQ2
uniprot id: A0A2Y9GF76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

29088:LOC110575807
gene id: 29088:LOC110575807
uniprot id: A0A2Y9GMM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:EIF5A
gene id: 29088:EIF5A
uniprot id: A0A2Y9HF89
uniprot id: A0A2Y9HLA2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

29088:TSHZ2
gene id: 29088:TSHZ2
uniprot id: A0A2Y9G5X8
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

29088:ORC6
gene id: 29088:ORC6
uniprot id: A0A2Y9IGE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

29088:SCG2
gene id: 29088:SCG2
uniprot id: A0A2Y9HIX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Interacts with Secretogranin III/SCG3.
messages: Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules.
messages: Secreted

29088:ASXL2
gene id: 29088:ASXL2
uniprot id: A0A2Y9HT96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asx family.
messages: Nucleus

29088:CFAP299
gene id: 29088:CFAP299
uniprot id: A0A2Y9I778
uniprot id: A0A8M1M6I8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in spermatogenesis.
messages: Nucleus

29088:DYM
gene id: 29088:DYM
uniprot id: A0A2Y9GRG4
names: Similarity
messages: Belongs to the dymeclin family.

29088:CCS
gene id: 29088:CCS
uniprot id: A0A2Y9GSG3
uniprot id: A0A2Y9GU42
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.

29088:PPP2R2D
gene id: 29088:PPP2R2D
uniprot id: A0A2Y9I613
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

29088:ABCC3
gene id: 29088:ABCC3
uniprot id: A0A2Y9IEA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

29088:DNAH12
gene id: 29088:DNAH12
uniprot id: A0A8M1MFW4
names: Similarity
messages: Belongs to the dynein heavy chain family.

29088:RPS12
gene id: 29088:RPS12
uniprot id: A0A2Y9HHC7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

29088:FAM83H
gene id: 29088:FAM83H
uniprot id: A0A2Y9GZP4
uniprot id: A0A2Y9GZV5
names: Similarity
messages: Belongs to the FAM83 family.

29088:PIAS2
gene id: 29088:PIAS2
uniprot id: A0A8M1MTM8
uniprot id: A0A8M1MVF9
names: Similarity
messages: Belongs to the PIAS family.

29088:LOC110586760
gene id: 29088:LOC110586760
uniprot id: A0A2Y9HLV6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:CA11
gene id: 29088:CA11
uniprot id: A0A2Y9GD12
uniprot id: A0A2Y9GHE0
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

29088:CYSLTR2
gene id: 29088:CYSLTR2
uniprot id: A0A2Y9H0S2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:PDE8B
gene id: 29088:PDE8B
uniprot id: A0A2Y9HV85
uniprot id: A0A2Y9HV89
uniprot id: A0A2Y9HVA8
uniprot id: A0A2Y9HVU1
uniprot id: A0A2Y9HVU5
uniprot id: A0A2Y9I0J5
uniprot id: A0A2Y9I0K6
uniprot id: A0A8M1MFM4
uniprot id: A0A8M1MJ24
uniprot id: A0A8M1MPE2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

29088:DGKH
gene id: 29088:DGKH
uniprot id: A0A2Y9HPG9
uniprot id: A0A2Y9HW05
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

29088:LOC110577840
gene id: 29088:LOC110577840
uniprot id: A0A2Y9H0G2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:CXXC5
gene id: 29088:CXXC5
uniprot id: A0A2Y9I126
uniprot id: A0A2Y9I5J4
names: Subcellular Location Annotation
messages: Cytoplasm

29088:NAMPT
gene id: 29088:NAMPT
uniprot id: A0A2Y9GHP2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

29088:GRK7
gene id: 29088:GRK7
uniprot id: A0A2Y9G695
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

29088:TRIM45
gene id: 29088:TRIM45
uniprot id: A0A2Y9H995
uniprot id: A0A8M1M852
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

29088:RPL14
gene id: 29088:RPL14
uniprot id: A0A2Y9G2X2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

29088:TOR1AIP1
gene id: 29088:TOR1AIP1
uniprot id: A0A2Y9GH49
uniprot id: A0A2Y9GM21
uniprot id: A0A8M1MGT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

29088:MASP2
gene id: 29088:MASP2
uniprot id: A0A2Y9GKT3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:HSPA5
gene id: 29088:HSPA5
uniprot id: A0A2Y9HDP3
uniprot id: A0A8M1MS17
uniprot id: A0A8M1MS26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Endoplasmic reticulum lumen

29088:AFMID
gene id: 29088:AFMID
uniprot id: A0A2Y9GG60
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynurenine formamidase family.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
messages: Homodimer.
messages: Nucleus
messages: The main chain amide nitrogen atoms of the second glycine and its adjacent residue in the HGGXW motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
messages: cytosol

29088:NKAIN1
gene id: 29088:NKAIN1
uniprot id: A0A2Y9GPP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

29088:LAMB3
gene id: 29088:LAMB3
uniprot id: A0A2Y9GGZ1
uniprot id: A0A2Y9GH27
uniprot id: A0A2Y9GKB0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110587672
gene id: 29088:LOC110587672
uniprot id: A0A2Y9HUM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm
messages: nucleoplasm

29088:ESRRA
gene id: 29088:ESRRA
uniprot id: A0A2Y9GN36
uniprot id: A0A2Y9GNF2
uniprot id: A0A2Y9GTV0
uniprot id: A0A8M1MPM3
uniprot id: A0A8M1MRI0
uniprot id: A0A8M1MSW0
uniprot id: A0A8M1MY06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

29088:GDPD3
gene id: 29088:GDPD3
uniprot id: A0A2Y9I3P6
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

29088:LSS
gene id: 29088:LSS
uniprot id: A0A2Y9G781
uniprot id: A0A2Y9G9R9
uniprot id: A0A2Y9GAT3
uniprot id: A0A8M1MMZ3
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

29088:EMX1
gene id: 29088:EMX1
uniprot id: A0A2Y9HYF5
uniprot id: A0A2Y9HZZ9
names: Subcellular Location Annotation
messages: Nucleus

29088:MIOX
gene id: 29088:MIOX
uniprot id: A0A2Y9GW14
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

29088:RBCK1
gene id: 29088:RBCK1
uniprot id: A0A2Y9GZU4
uniprot id: A0A2Y9H008
uniprot id: A0A2Y9H6E1
names: Similarity
messages: Belongs to the RBR family.

29088:WAPL
gene id: 29088:WAPL
uniprot id: A0A2Y9HUX4
uniprot id: A0A2Y9HVH6
uniprot id: A0A2Y9I094
names: Similarity
messages: Belongs to the WAPL family.

29088:NOTCH2
gene id: 29088:NOTCH2
uniprot id: A0A2Y9H2L6
uniprot id: A0A8M1M9R5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

29088:HABP4
gene id: 29088:HABP4
uniprot id: A0A2Y9G3H5
uniprot id: A0A2Y9G3Z3
uniprot id: A0A8M1MTI1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:GATA1
gene id: 29088:GATA1
uniprot id: A0A2Y9G6F8
names: Subcellular Location Annotation
messages: Nucleus

29088:IGFBP1
gene id: 29088:IGFBP1
uniprot id: A0A2Y9I5X0
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:HMGCS2
gene id: 29088:HMGCS2
uniprot id: A0A2Y9H8T1
uniprot id: A0A8M1MAK4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

29088:LYNX1
gene id: 29088:LYNX1
uniprot id: A0A2Y9GXX0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:SMAD9
gene id: 29088:SMAD9
uniprot id: A0A2Y9G876
uniprot id: A0A8M1M7Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

29088:LSM2
gene id: 29088:LSM2
uniprot id: A0A2Y9HLS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

29088:LOC110576154
gene id: 29088:LOC110576154
uniprot id: A0A2Y9GUH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110573431
gene id: 29088:LOC110573431
uniprot id: A0A2Y9GEV5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:CNOT6
gene id: 29088:CNOT6
uniprot id: A0A8M1MJ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

29088:LOC110584974
gene id: 29088:LOC110584974
uniprot id: A0A8M1MP65
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

29088:LOC110589382
gene id: 29088:LOC110589382
uniprot id: A0A8M1MHQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

29088:NR3C2
gene id: 29088:NR3C2
uniprot id: A0A2Y9HSA8
names: Subcellular Location Annotation
messages: Nucleus

29088:PPP2R5D
gene id: 29088:PPP2R5D
uniprot id: A0A2Y9H7X8
uniprot id: A0A8M1MHZ5
uniprot id: A0A8M1MHZ6
uniprot id: A0A8M1MK17
uniprot id: A0A8M1MRX3
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

29088:FGF19
gene id: 29088:FGF19
uniprot id: A0A2Y9GSX8
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

29088:PTH2R
gene id: 29088:PTH2R
uniprot id: A0A2Y9I9H1
uniprot id: A0A8M1M9X6
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110590956
gene id: 29088:LOC110590956
uniprot id: A0A2Y9I0K7
names: Function
names: Similarity
names: Subunit
messages: Component of the 40S subunit of the ribosome.
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Ribosomal protein S27a is part of the 40S ribosomal subunit.

29088:GPAT4
gene id: 29088:GPAT4
uniprot id: A0A2Y9GDZ6
uniprot id: A0A2Y9GE17
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

29088:THUMPD2
gene id: 29088:THUMPD2
uniprot id: A0A2Y9HTL6
uniprot id: A0A2Y9HV25
names: Similarity
messages: Belongs to the methyltransferase superfamily.

29088:UGGT1
gene id: 29088:UGGT1
uniprot id: A0A2Y9HIL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

29088:SHFL
gene id: 29088:SHFL
uniprot id: A0A2Y9IAE1
uniprot id: A0A2Y9IET9
uniprot id: A0A8M1MTK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHFL family.
messages: Nucleus
messages: P-body

29088:CTBP1
gene id: 29088:CTBP1
uniprot id: A0A2Y9G2U4
uniprot id: A0A2Y9G3F8
uniprot id: A0A2Y9G5G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

29088:PELI1
gene id: 29088:PELI1
uniprot id: A0A2Y9HT34
names: Function
names: Similarity
messages: Belongs to the pellino family.
messages: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

29088:GRB10
gene id: 29088:GRB10
uniprot id: A0A8M1MSL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

29088:LOC110574198
gene id: 29088:LOC110574198
uniprot id: A0A2Y9GHD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

29088:LOC110582814
gene id: 29088:LOC110582814
uniprot id: A0A2Y9HFS7
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:PHYKPL
gene id: 29088:PHYKPL
uniprot id: A0A2Y9I1S1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

29088:CCT8L2
gene id: 29088:CCT8L2
uniprot id: A0A2Y9H9X0
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

29088:MAGI1
gene id: 29088:MAGI1
uniprot id: A0A8M1MTK3
uniprot id: A0A8M1MVD9
uniprot id: A0A8M1MWP0
uniprot id: A0A8M1MWP3
uniprot id: A0A8M1MYY2
names: Subcellular Location Annotation
messages: Membrane

29088:IQSEC2
gene id: 29088:IQSEC2
uniprot id: A0A8M1M1N6
uniprot id: A0A8M1M5E9
names: Similarity
messages: Belongs to the BRAG family.

29088:SMAD2
gene id: 29088:SMAD2
uniprot id: A0A2Y9GVZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

29088:ILK
gene id: 29088:ILK
uniprot id: A0A2Y9GQ16
uniprot id: A0A2Y9GQC5
names: Subcellular Location Annotation
messages: focal adhesion
messages: lamellipodium
messages: sarcomere

29088:MFSD11
gene id: 29088:MFSD11
uniprot id: A0A2Y9GGN0
uniprot id: A0A8M1MWQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

29088:ATP6AP2
gene id: 29088:ATP6AP2
uniprot id: A0A2Y9GEH2
uniprot id: A0A2Y9GHJ2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

29088:SNRPA1
gene id: 29088:SNRPA1
uniprot id: A0A2Y9GB11
uniprot id: A0A2Y9GB29
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

29088:ABCB6
gene id: 29088:ABCB6
uniprot id: A0A2Y9I3C8
uniprot id: A0A2Y9I3L1
uniprot id: A0A8M1M8K4
uniprot id: A0A8M1MEB6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Late endosome membrane
messages: Lysosome membrane
messages: Melanosome membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: extracellular exosome
messages: multivesicular body membrane

29088:MYSM1
gene id: 29088:MYSM1
uniprot id: A0A2Y9GP04
names: Similarity
messages: Belongs to the peptidase M67A family. MYSM1 subfamily.

29088:IGF2
gene id: 29088:IGF2
uniprot id: A0A2Y9GNW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Interacts with MYORG; this interaction is required for IGF2 secretion. Interacts with integrins ITGAV:ITGB3 and ITGA6:ITGB4; integrin-binding is required for IGF2 signaling.
messages: Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
messages: Secreted
messages: The insulin-like growth factors possess growth-promoting activity (By similarity). Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF2 is influenced by placental lactogen. Also involved in tissue differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver. Acts as a ligand for integrin which is required for IGF2 signaling. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation (By similarity). Inhibits myoblast differentiation and modulates metabolism via increasing the mitochondrial respiration rate.

29088:MCCC2
gene id: 29088:MCCC2
uniprot id: A0A2Y9HWB1
uniprot id: A0A8M1MP91
names: Similarity
messages: Belongs to the AccD/PCCB family.

29088:LOC110581036
gene id: 29088:LOC110581036
uniprot id: A0A2Y9H453
names: Similarity
messages: Belongs to the taxilin family.

29088:NTF4
gene id: 29088:NTF4
uniprot id: A0A2Y9GHF9
names: Similarity
messages: Belongs to the NGF-beta family.

29088:TCF7L2
gene id: 29088:TCF7L2
uniprot id: A0A8M1MDZ7
uniprot id: A0A8M1ME02
uniprot id: A0A8M1ME07
uniprot id: A0A8M1ME12
uniprot id: A0A8M1ME44
uniprot id: A0A8M1ME48
uniprot id: A0A8M1ME52
uniprot id: A0A8M1MG55
uniprot id: A0A8M1MG59
uniprot id: A0A8M1MG64
uniprot id: A0A8M1MG69
uniprot id: A0A8M1MHK1
uniprot id: A0A8M1MHK6
uniprot id: A0A8M1MHL0
uniprot id: A0A8M1MMP6
uniprot id: A0A8M1MMQ2
uniprot id: A0A8M1MMQ7
uniprot id: A0A8M1MMR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

29088:FAM163B
gene id: 29088:FAM163B
uniprot id: A0A2Y9H6R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

29088:TMEM65
gene id: 29088:TMEM65
uniprot id: A0A2Y9GXR4
names: Subcellular Location Annotation
messages: Membrane

29088:CPXM2
gene id: 29088:CPXM2
uniprot id: A0A8M1MHS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

29088:GFOD1
gene id: 29088:GFOD1
uniprot id: A0A2Y9HM07
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

29088:SIM2
gene id: 29088:SIM2
uniprot id: A0A8M1MWD4
names: Subcellular Location Annotation
messages: Nucleus

29088:CASC3
gene id: 29088:CASC3
uniprot id: A0A2Y9I6Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASC3 family.
messages: Nucleus speckle
messages: dendrite
messages: perinuclear region

29088:LOC110578664
gene id: 29088:LOC110578664
uniprot id: A0A2Y9GXD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

29088:DKK2
gene id: 29088:DKK2
uniprot id: A0A2Y9GQS4
names: Similarity
messages: Belongs to the dickkopf family.

29088:GRHL3
gene id: 29088:GRHL3
uniprot id: A0A2Y9GKS3
uniprot id: A0A2Y9GPJ2
uniprot id: A0A2Y9GR64
names: Subcellular Location Annotation
messages: Nucleus

29088:STK11
gene id: 29088:STK11
uniprot id: A0A2Y9IAX9
uniprot id: A0A2Y9IB14
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. LKB1 subfamily.

29088:CDC26
gene id: 29088:CDC26
uniprot id: A0A2Y9H682
names: Function
names: Similarity
messages: Belongs to the CDC26 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.

29088:PARD6A
gene id: 29088:PARD6A
uniprot id: A0A2Y9I6K1
uniprot id: A0A2Y9IAL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

29088:SLC16A14
gene id: 29088:SLC16A14
uniprot id: A0A2Y9GMS2
names: Subcellular Location Annotation
messages: Membrane

29088:PTPN11
gene id: 29088:PTPN11
uniprot id: A0A2Y9HW85
uniprot id: A0A2Y9HXT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

29088:VPS18
gene id: 29088:VPS18
uniprot id: A0A2Y9HNE1
uniprot id: A0A2Y9HNU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

29088:FDFT1
gene id: 29088:FDFT1
uniprot id: A0A2Y9HSV4
uniprot id: A0A2Y9HXR5
uniprot id: A0A2Y9HZA4
uniprot id: A0A8M1M4U0
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

29088:GPR137C
gene id: 29088:GPR137C
uniprot id: A0A2Y9I4N0
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

29088:DACT2
gene id: 29088:DACT2
uniprot id: A0A2Y9HBD0
names: Similarity
messages: Belongs to the dapper family.

29088:MYLK4
gene id: 29088:MYLK4
uniprot id: A0A2Y9HTS2
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:PDE4D
gene id: 29088:PDE4D
uniprot id: A0A2Y9I1K7
uniprot id: A0A2Y9I1T6
uniprot id: A0A2Y9I222
uniprot id: A0A2Y9I228
uniprot id: A0A2Y9I6G5
uniprot id: A0A2Y9I8K7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

29088:CNTNAP2
gene id: 29088:CNTNAP2
uniprot id: A0A8M1MQ38
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: paranodal septate junction

29088:MYCBP2
gene id: 29088:MYCBP2
uniprot id: A0A8M1M8Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RING-Cys relay (RCR) family.
messages: axon

29088:PGAP3
gene id: 29088:PGAP3
uniprot id: A0A2Y9I6T6
uniprot id: A0A2Y9I765
uniprot id: A0A8M1MU73
uniprot id: A0A8M1MW03
uniprot id: A0A8M1MX26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Golgi apparatus membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:ADORA2B
gene id: 29088:ADORA2B
uniprot id: A0A2Y9HFE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

29088:DCAF10
gene id: 29088:DCAF10
uniprot id: A0A2Y9HC94
names: Function
names: Similarity
messages: Belongs to the WD repeat DCAF10 family.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

29088:SLC6A17
gene id: 29088:SLC6A17
uniprot id: A0A2Y9H2K1
uniprot id: A0A2Y9H970
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

29088:NOL12
gene id: 29088:NOL12
uniprot id: A0A2Y9GVQ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP17 family.
messages: Interacts with KIAA1191.
messages: nucleolus

29088:LOC110588046
gene id: 29088:LOC110588046
uniprot id: A0A2Y9HVR4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

29088:SLC11A1
gene id: 29088:SLC11A1
uniprot id: A0A2Y9I3M7
uniprot id: A0A2Y9I3V5
uniprot id: A0A2Y9I481
uniprot id: A0A2Y9I8G0
names: Function
names: Similarity
messages: Belongs to the NRAMP family.
messages: Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.

29088:MPV17L
gene id: 29088:MPV17L
uniprot id: A0A2Y9HVN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

29088:LIPK
gene id: 29088:LIPK
uniprot id: A0A2Y9HQ82
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

29088:NME7
gene id: 29088:NME7
uniprot id: A0A8M1MGA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: cilium axoneme

29088:LOC110577417
gene id: 29088:LOC110577417
uniprot id: A0A2Y9GSY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:CUX2
gene id: 29088:CUX2
uniprot id: A0A8M1MT52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

29088:FZD6
gene id: 29088:FZD6
uniprot id: A0A2Y9GXB6
uniprot id: A0A2Y9GXK6
uniprot id: A0A2Y9H1R0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Cell surface
messages: Cytoplasmic vesicle membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:LOC123324053
gene id: 29088:LOC123324053
uniprot id: A0A8M1M6Q4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

29088:LOC110583310
gene id: 29088:LOC110583310
uniprot id: A0A2Y9HBH0
uniprot id: A0A2Y9HI04
uniprot id: A0A8M1MHJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

29088:SF3B3
gene id: 29088:SF3B3
uniprot id: A0A2Y9IBL3
uniprot id: A0A2Y9IBR6
names: Subcellular Location Annotation
messages: Nucleus

29088:RFC1
gene id: 29088:RFC1
uniprot id: A0A8M1MC80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

29088:USE1
gene id: 29088:USE1
uniprot id: A0A2Y9GLI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:LOC110576121
gene id: 29088:LOC110576121
uniprot id: A0A2Y9GNZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:DSEL
gene id: 29088:DSEL
uniprot id: A0A2Y9GS19
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

29088:OGT
gene id: 29088:OGT
uniprot id: A0A2Y9GBG9
uniprot id: A0A8M1M1P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Cell projection
messages: Mitochondrion membrane

29088:GAL
gene id: 29088:GAL
uniprot id: A0A2Y9GP59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galanin family.
messages: Secreted

29088:CSNK1G3
gene id: 29088:CSNK1G3
uniprot id: A0A2Y9I1Y2
uniprot id: A0A2Y9I267
uniprot id: A0A2Y9I6K7
uniprot id: A0A2Y9I8P5
uniprot id: A0A8M1MK90
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

29088:ZNRF4
gene id: 29088:ZNRF4
uniprot id: A0A2Y9IIK0
names: Subcellular Location Annotation
messages: Membrane

29088:FADS1
gene id: 29088:FADS1
uniprot id: A0A2Y9GPQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Endoplasmic reticulum membrane

29088:SEMA7A
gene id: 29088:SEMA7A
uniprot id: A0A2Y9HJG5
uniprot id: A0A8M1MJ90
uniprot id: A0A8M1MML4
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:XKR9
gene id: 29088:XKR9
uniprot id: A0A2Y9H4V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

29088:STARD6
gene id: 29088:STARD6
uniprot id: A0A2Y9GW18
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

29088:ENTPD2
gene id: 29088:ENTPD2
uniprot id: A0A2Y9H4Z5
uniprot id: A0A8M1MRR5
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

29088:GLO1
gene id: 29088:GLO1
uniprot id: A0A2Y9GM38
uniprot id: A0A2Y9GM75
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

29088:CRB2
gene id: 29088:CRB2
uniprot id: A0A8M1MR83
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:TPST1
gene id: 29088:TPST1
uniprot id: A0A2Y9HWZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

29088:HNRNPU
gene id: 29088:HNRNPU
uniprot id: A0A2Y9H6U4
uniprot id: A0A2Y9H8F4
uniprot id: A0A8M1MH24
uniprot id: A0A8M1MM54
names: Subcellular Location Annotation
messages: Nucleus

29088:FGF3
gene id: 29088:FGF3
uniprot id: A0A2Y9GP24
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

29088:LOC110576465
gene id: 29088:LOC110576465
uniprot id: A0A2Y9GQ36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ZYG11B
gene id: 29088:ZYG11B
uniprot id: A0A2Y9GLM4
names: Similarity
messages: Belongs to the zyg-11 family.

29088:EMG1
gene id: 29088:EMG1
uniprot id: A0A2Y9H3M5
uniprot id: A0A8M1MEA2
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

29088:KIF5A
gene id: 29088:KIF5A
uniprot id: A0A2Y9GUP4
uniprot id: A0A8M1MDT3
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:HSD3B7
gene id: 29088:HSD3B7
uniprot id: A0A2Y9HXA1
uniprot id: A0A2Y9I3N7
names: Similarity
messages: Belongs to the 3-beta-HSD family.

29088:REV3L
gene id: 29088:REV3L
uniprot id: A0A2Y9HID1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

29088:C10H2orf49
gene id: 29088:C10H2orf49
uniprot id: A0A2Y9GE82
uniprot id: A0A8M1MVG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ashwin family.
messages: Nucleus

29088:RBFOX2
gene id: 29088:RBFOX2
uniprot id: A0A8M1MBP4
uniprot id: A0A8M1MBP9
uniprot id: A0A8M1MBU5
uniprot id: A0A8M1MDY4
uniprot id: A0A8M1MFC3
uniprot id: A0A8M1MK81
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

29088:FAM53A
gene id: 29088:FAM53A
uniprot id: A0A2Y9G6K7
names: Similarity
messages: Belongs to the FAM53 family.

29088:HNF4G
gene id: 29088:HNF4G
uniprot id: A0A2Y9H275
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

29088:LOC110587725
gene id: 29088:LOC110587725
uniprot id: A0A8M1MDK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:MAEL
gene id: 29088:MAEL
uniprot id: A0A2Y9GGW0
uniprot id: A0A2Y9GLU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the maelstrom family.
messages: Nucleus
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage.

29088:ZC2HC1C
gene id: 29088:ZC2HC1C
uniprot id: A0A2Y9G8A3
names: Similarity
messages: Belongs to the ZC2HC1 family.

29088:MFSD10
gene id: 29088:MFSD10
uniprot id: A0A2Y9G2J7
uniprot id: A0A2Y9G2K6
uniprot id: A0A2Y9G2Q2
uniprot id: A0A2Y9G360
uniprot id: A0A2Y9G574
uniprot id: A0A2Y9G6B2
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110582490
gene id: 29088:LOC110582490
uniprot id: A0A2Y9HFT3
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

29088:PRIMPOL
gene id: 29088:PRIMPOL
uniprot id: A0A2Y9HDL5
uniprot id: A0A2Y9HK23
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

29088:PABPC1
gene id: 29088:PABPC1
uniprot id: A0A2Y9H323
uniprot id: A0A2Y9H512
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

29088:COPS6
gene id: 29088:COPS6
uniprot id: A0A2Y9GCH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN6 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.
messages: Cytoplasm
messages: Nucleus

29088:PIAS1
gene id: 29088:PIAS1
uniprot id: A0A2Y9HIP1
names: Similarity
messages: Belongs to the PIAS family.

29088:PDK4
gene id: 29088:PDK4
uniprot id: A0A2Y9H6C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

29088:HSPE1
gene id: 29088:HSPE1
uniprot id: A0A2Y9HKK2
names: Similarity
messages: Belongs to the GroES chaperonin family.

29088:FITM2
gene id: 29088:FITM2
uniprot id: A0A2Y9GZI7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:LOC110580929
gene id: 29088:LOC110580929
uniprot id: A0A8M1ME43
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

29088:LOC110587203
gene id: 29088:LOC110587203
uniprot id: A0A2Y9HT88
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:DOCK7
gene id: 29088:DOCK7
uniprot id: A0A8M1MBP6
names: Similarity
messages: Belongs to the DOCK family.

29088:FOXD3
gene id: 29088:FOXD3
uniprot id: A0A2Y9GD61
names: Subcellular Location Annotation
messages: Nucleus

29088:MAN1C1
gene id: 29088:MAN1C1
uniprot id: A0A8M1M926
uniprot id: A0A8M1MBG2
uniprot id: A0A8M1MHH5
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

29088:LOC110586222
gene id: 29088:LOC110586222
uniprot id: A0A2Y9HK92
names: Similarity
messages: Belongs to the peptidase M10A family.

29088:LTBP2
gene id: 29088:LTBP2
uniprot id: A0A2Y9G8Z7
uniprot id: A0A2Y9G944
uniprot id: A0A2Y9GBJ1
uniprot id: A0A2Y9GBJ5
uniprot id: A0A2Y9GCI4
uniprot id: A0A8M1MIZ6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:POLE2
gene id: 29088:POLE2
uniprot id: A0A2Y9I4B9
uniprot id: A0A2Y9I667
uniprot id: A0A8M1MJ02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus
messages: Participates in DNA repair and in chromosomal DNA replication.

29088:TP53INP2
gene id: 29088:TP53INP2
uniprot id: A0A2Y9GZF3
uniprot id: A0A8M1MN17
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

29088:LOC110589688
gene id: 29088:LOC110589688
uniprot id: A0A2Y9HWK2
uniprot id: A0A2Y9I2W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCMBP family.
messages: Nucleus

29088:HSD17B13
gene id: 29088:HSD17B13
uniprot id: A0A2Y9I6U8
uniprot id: A0A2Y9I8X8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:MAN2B2
gene id: 29088:MAN2B2
uniprot id: A0A8M1MDE3
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

29088:BORCS5
gene id: 29088:BORCS5
uniprot id: A0A2Y9H3P0
uniprot id: A0A2Y9H3Q1
uniprot id: A0A8M1MAG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS5 family.
messages: Lysosome membrane
messages: Membrane

29088:KLHL3
gene id: 29088:KLHL3
uniprot id: A0A2Y9I5S2
names: Subcellular Location Annotation
messages: cytoskeleton
messages: cytosol

29088:TMA7
gene id: 29088:TMA7
uniprot id: A0A2Y9IJE9
names: Similarity
messages: Belongs to the TMA7 family.

29088:RELL2
gene id: 29088:RELL2
uniprot id: A0A2Y9I0D2
names: Similarity
messages: Belongs to the RELT family.

29088:LOC110570935
gene id: 29088:LOC110570935
uniprot id: A0A2Y9G720
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:SLC4A1
gene id: 29088:SLC4A1
uniprot id: A0A2Y9GE02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine.
messages: Membrane

29088:P2RY1
gene id: 29088:P2RY1
uniprot id: A0A2Y9GQZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:CHST3
gene id: 29088:CHST3
uniprot id: A0A2Y9I0P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

29088:CDO1
gene id: 29088:CDO1
uniprot id: A0A2Y9I1T5
uniprot id: A0A8M1MK61
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.

29088:IP6K2
gene id: 29088:IP6K2
uniprot id: A0A2Y9GTN5
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

29088:PPAT
gene id: 29088:PPAT
uniprot id: A0A2Y9I6R9
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

29088:DIS3
gene id: 29088:DIS3
uniprot id: A0A2Y9HVZ3
names: Similarity
messages: Belongs to the RNR ribonuclease family.

29088:CDKN1A
gene id: 29088:CDKN1A
uniprot id: A0A2Y9GME1
uniprot id: A0A8M1MKP0
names: Similarity
messages: Belongs to the CDI family.

29088:LOC110589036
gene id: 29088:LOC110589036
uniprot id: A0A2Y9HU45
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

29088:LOC123323407
gene id: 29088:LOC123323407
uniprot id: A0A2Y9HDM8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:RAD52
gene id: 29088:RAD52
uniprot id: A0A8M1MCX6
names: Similarity
messages: Belongs to the RAD52 family.

29088:LOC110573434
gene id: 29088:LOC110573434
uniprot id: A0A2Y9GJG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:EFNA4
gene id: 29088:EFNA4
uniprot id: A0A2Y9GK55
uniprot id: A0A8M1MD58
uniprot id: A0A8M1MFC4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:LOC110575253
gene id: 29088:LOC110575253
uniprot id: A0A2Y9GL25
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flavin monoamine oxidase family.
messages: Mitochondrion outer membrane
messages: Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer.

29088:SLC25A34
gene id: 29088:SLC25A34
uniprot id: A0A2Y9GIZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:SCGB1A1
gene id: 29088:SCGB1A1
uniprot id: A0A2Y9GNS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secretoglobin family.
messages: Secreted

29088:BNIP1
gene id: 29088:BNIP1
uniprot id: A0A2Y9HQS3
uniprot id: A0A8M1MJF2
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110591916
gene id: 29088:LOC110591916
uniprot id: A0A2Y9I495
uniprot id: A0A8M1M8H3
uniprot id: A0A8M1ME82
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:PTMS
gene id: 29088:PTMS
uniprot id: A0A2Y9H382
names: Similarity
messages: Belongs to the pro/parathymosin family.

29088:JPH2
gene id: 29088:JPH2
uniprot id: A0A2Y9H6G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:MAP3K7
gene id: 29088:MAP3K7
uniprot id: A0A2Y9HC88
uniprot id: A0A2Y9HCF3
uniprot id: A0A8M1MIB4
uniprot id: A0A8M1MKD6
uniprot id: A0A8M1MSA3
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by pro-inflammatory cytokines and in response to physical and chemical stresses, including osmotic stress, oxidative stress, arsenic and ultraviolet light irradiation. Activated by 'Lys-63'-linked polyubiquitination and by autophosphorylation.
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cytoplasm

29088:ZC3H12A
gene id: 29088:ZC3H12A
uniprot id: A0A8M1MBJ0
names: Similarity
messages: Belongs to the ZC3H12 family.

29088:POU4F2
gene id: 29088:POU4F2
uniprot id: A0A2Y9GA17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

29088:LRRC51
gene id: 29088:LRRC51
uniprot id: A0A8M1MS80
uniprot id: A0A8M1MXP8
names: Subcellular Location Annotation
messages: Cytoplasm

29088:LOC110585349
gene id: 29088:LOC110585349
uniprot id: A0A2Y9HP46
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SCAMP4
gene id: 29088:SCAMP4
uniprot id: A0A2Y9I9X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

29088:USB1
gene id: 29088:USB1
uniprot id: A0A2Y9I7R9
uniprot id: A0A2Y9IF54
uniprot id: A0A8M1MZG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2H phosphoesterase superfamily. USB1 family.
messages: Nucleus
messages: Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate.

29088:CCNY
gene id: 29088:CCNY
uniprot id: A0A8M1MC99
uniprot id: A0A8M1MFR9
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

29088:LOC123326185
gene id: 29088:LOC123326185
uniprot id: A0A8M1MN14
names: Similarity
messages: Belongs to the syntaxin family.

29088:API5
gene id: 29088:API5
uniprot id: A0A2Y9GPC4
uniprot id: A0A2Y9GPG4
uniprot id: A0A8M1MNA1
uniprot id: A0A8M1MQ82
names: Similarity
messages: Belongs to the API5 family.

29088:HARS1
gene id: 29088:HARS1
uniprot id: A0A2Y9I0G3
uniprot id: A0A2Y9I0S0
uniprot id: A0A2Y9I0Y1
uniprot id: A0A2Y9I7F2
uniprot id: A0A8M1MFN1
uniprot id: A0A8M1MFN5
uniprot id: A0A8M1MHR8
uniprot id: A0A8M1MJ40
uniprot id: A0A8M1MPG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

29088:NDRG2
gene id: 29088:NDRG2
uniprot id: A0A2Y9HH93
uniprot id: A0A2Y9HHI8
uniprot id: A0A2Y9HHJ4
uniprot id: A0A2Y9HNE9
uniprot id: A0A2Y9HNV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDRG family.
messages: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation.
messages: Cytoplasm

29088:LOC110578343
gene id: 29088:LOC110578343
uniprot id: A0A8M1MWI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

29088:SEMA6D
gene id: 29088:SEMA6D
uniprot id: A0A8M1MSR9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:OPRD1
gene id: 29088:OPRD1
uniprot id: A0A2Y9GN07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:OPN3
gene id: 29088:OPN3
uniprot id: A0A2Y9GGX8
uniprot id: A0A8M1MES6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

29088:UCKL1
gene id: 29088:UCKL1
uniprot id: A0A2Y9G2X0
uniprot id: A0A2Y9G324
uniprot id: A0A2Y9G6N4
uniprot id: A0A8M1MMC8
uniprot id: A0A8M1MMD1
uniprot id: A0A8M1MPC0
uniprot id: A0A8M1MPC4
uniprot id: A0A8M1MQN0
uniprot id: A0A8M1MWL8
names: Similarity
messages: Belongs to the uridine kinase family.

29088:KIN
gene id: 29088:KIN
uniprot id: A0A2Y9HKY9
names: Similarity
messages: Belongs to the KIN17 family.

29088:CLDN7
gene id: 29088:CLDN7
uniprot id: A0A2Y9HLB1
uniprot id: A0A8M1MX47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

29088:FBXL5
gene id: 29088:FBXL5
uniprot id: A0A8M1M514
uniprot id: A0A8M1M5B7
names: Subcellular Location Annotation
messages: perinuclear region

29088:U2AF2
gene id: 29088:U2AF2
uniprot id: A0A2Y9GFZ2
uniprot id: A0A2Y9GG09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

29088:MCM3
gene id: 29088:MCM3
uniprot id: A0A2Y9H7N4
uniprot id: A0A8M1MJG3
uniprot id: A0A8M1MKR3
uniprot id: A0A8M1MRA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

29088:LOC110572667
gene id: 29088:LOC110572667
uniprot id: A0A2Y9GCJ9
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

29088:SNX31
gene id: 29088:SNX31
uniprot id: A0A2Y9GYL6
names: Similarity
messages: Belongs to the sorting nexin family.

29088:NPPA
gene id: 29088:NPPA
uniprot id: A0A2Y9GP71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the natriuretic peptide family.
messages: Cell projection
messages: Homodimer; disulfide-linked antiparallel dimer.
messages: Hormone produced in the kidneys that appears to be important for maintaining cardio-renal homeostasis. Mediates vasodilation, natriuresis and diuresis primarily in the renal system, in order to maintain the extracellular fluid volume and control the fluid-electrolyte balance. Specifically binds and stimulates cGMP production by renal transmembrane receptors, likely NPR1. Urodilatin not ANP, may be the natriuretic peptide responsible for the regulation of sodium and water homeostasis in the kidney.
messages: May have a role in cardio-renal homeostasis through regulation of diuresis and inhibiting aldosterone synthesis. In vitro, promotes the production of cGMP and induces vasodilation. May promote natriuresis, at least in part, by enhancing prostaglandin E2 synthesis resulting in the inhibition of renal Na+-K+-ATPase. May have a role in potassium excretion but not sodium excretion (natriuresis). Possibly enhances protein excretion in urine by decreasing proximal tubular protein reabsorption.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation. In vivo promotes natriuresis and in vitro, vasodilates renal artery strips.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, selectively vasodilates intestinal and vascular smooth muscle strips.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, selectively vasodilates intestinal smooth muscle but not vascular smooth muscle strips.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis, diuresis, and vasodilation. In vitro, promotes the production of cGMP and induces vasodilation. May promote natriuresis, at least in part, by enhancing prostaglandin E2 synthesis resulting in the inhibition of renal Na+-K+-ATPase. However reports on the involvement of this peptide in mammal blood volume and blood pressure homeostasis are conflicting; according to a report it is not sufficient to activate cGMP and does not inhibit collecting duct transport nor effect diuresis and natriuresis. Appears to bind to specific receptors that are distinct from the receptors bound by the atrial natriuretic and long-acting natriuretic peptides. Possibly functions in protein excretion in urine by maintaining the integrity of the proximal tubules and enhancing protein excretion by decreasing proximal tubular protein reabsorption.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis, diuresis, vasodilation, and inhibiting aldosterone synthesis. In vitro, promotes the production of cGMP and induces vasodilation. May promote natriuresis, at least in part, by enhancing prostaglandin E2 synthesis resulting in the inhibition of renal Na+-K+-ATPase (By similarity). However reports on the involvement of this peptide in mammal blood volume and blood pressure homeostasis are conflicting; according to a report, in vivo it is not sufficient to activate cGMP and does not inhibit collecting duct transport nor effect diuresis and natriuresis (By similarity). Appears to bind to specific receptors that are distinct from the receptors bound by atrial natriuretic peptide and vessel dilator. Possibly enhances protein excretion in urine by decreasing proximal tubular protein reabsorption.
messages: May have a role in cardio-renal homeostasis through regulation of regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, vasodilates intestinal smooth muscle but not smooth muscle strips.
messages: Secreted

29088:TGFB1I1
gene id: 29088:TGFB1I1
uniprot id: A0A2Y9I400
uniprot id: A0A8M1MEX2
names: Similarity
messages: Belongs to the paxillin family.

29088:LOC110576408
gene id: 29088:LOC110576408
uniprot id: A0A2Y9GPR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110591285
gene id: 29088:LOC110591285
uniprot id: A0A2Y9I8K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:PEX2
gene id: 29088:PEX2
uniprot id: A0A2Y9GXE2
names: Function
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.
messages: Somewhat implicated in the biogenesis of peroxisomes.

29088:RAF1
gene id: 29088:RAF1
uniprot id: A0A2Y9HGE7
uniprot id: A0A8M1MUT1
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

29088:SEMA3B
gene id: 29088:SEMA3B
uniprot id: A0A2Y9GY15
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:TM7SF2
gene id: 29088:TM7SF2
uniprot id: A0A2Y9GPK1
uniprot id: A0A2Y9GVC7
uniprot id: A0A8M1MX74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

29088:TUBGCP5
gene id: 29088:TUBGCP5
uniprot id: A0A2Y9GF29
uniprot id: A0A8M1MML9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

29088:STEEP1
gene id: 29088:STEEP1
uniprot id: A0A2Y9GRQ3
uniprot id: A0A8M1M1K7
names: Similarity
messages: Belongs to the STEEP1 family.

29088:CELF5
gene id: 29088:CELF5
uniprot id: A0A8M1MKY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

29088:ACAD11
gene id: 29088:ACAD11
uniprot id: A0A8M1MG56
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

29088:LOC110574370
gene id: 29088:LOC110574370
uniprot id: A0A2Y9GHW5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:RGS5
gene id: 29088:RGS5
uniprot id: A0A2Y9HXH8
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.

29088:CREB1
gene id: 29088:CREB1
uniprot id: A0A2Y9I4T9
uniprot id: A0A8M1M6Z7
names: Subcellular Location Annotation
messages: Nucleus

29088:KIFBP
gene id: 29088:KIFBP
uniprot id: A0A8M1MEY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

29088:TMEM43
gene id: 29088:TMEM43
uniprot id: A0A2Y9HMP1
uniprot id: A0A2Y9HMW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

29088:LOC110587811
gene id: 29088:LOC110587811
uniprot id: A0A2Y9HUV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110570654
gene id: 29088:LOC110570654
uniprot id: A0A8M1MVX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA3 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Membrane
messages: Mitochondrion inner membrane

29088:DEFB135
gene id: 29088:DEFB135
uniprot id: A0A2Y9HSE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

29088:GUCY1A1
gene id: 29088:GUCY1A1
uniprot id: A0A2Y9HSK9
uniprot id: A0A8M1M3T0
uniprot id: A0A8M1M440
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

29088:RPS6KB2
gene id: 29088:RPS6KB2
uniprot id: A0A2Y9GNI8
uniprot id: A0A2Y9GNS2
uniprot id: A0A8M1MPR6
uniprot id: A0A8M1MWY5
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

29088:ERRFI1
gene id: 29088:ERRFI1
uniprot id: A0A2Y9GIU1
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus

29088:ATOH7
gene id: 29088:ATOH7
uniprot id: A0A2Y9HVX5
names: Subcellular Location Annotation
messages: Nucleus
messages: Perikaryon
messages: axon

29088:LOC110585509
gene id: 29088:LOC110585509
uniprot id: A0A2Y9HHU7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:FAM124B
gene id: 29088:FAM124B
uniprot id: A0A2Y9GHQ8
names: Similarity
messages: Belongs to the FAM124 family.

29088:NCAN
gene id: 29088:NCAN
uniprot id: A0A2Y9GLB2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:LOC110571534
gene id: 29088:LOC110571534
uniprot id: A0A2Y9G8M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

29088:PLCB4
gene id: 29088:PLCB4
uniprot id: A0A2Y9GZ83
uniprot id: A0A2Y9GZE4
uniprot id: A0A2Y9GZE6
uniprot id: A0A8M1MP75
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

29088:CNTF
gene id: 29088:CNTF
uniprot id: A0A2Y9GPC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

29088:FEV
gene id: 29088:FEV
uniprot id: A0A2Y9I5A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

29088:CHAT
gene id: 29088:CHAT
uniprot id: A0A2Y9I0D3
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

29088:NCOA3
gene id: 29088:NCOA3
uniprot id: A0A2Y9H041
uniprot id: A0A2Y9H096
uniprot id: A0A2Y9H0A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

29088:NT5C3B
gene id: 29088:NT5C3B
uniprot id: A0A2Y9GE99
uniprot id: A0A2Y9GEE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

29088:LOC110593873
gene id: 29088:LOC110593873
uniprot id: A0A2Y9IF08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TNFSF13B
gene id: 29088:TNFSF13B
uniprot id: A0A2Y9HPU6
names: Similarity
messages: Belongs to the tumor necrosis factor family.

29088:OSBPL8
gene id: 29088:OSBPL8
uniprot id: A0A8M1MBS4
uniprot id: A0A8M1MBX4
uniprot id: A0A8M1ME08
names: Similarity
messages: Belongs to the OSBP family.

29088:DNAJC24
gene id: 29088:DNAJC24
uniprot id: A0A2Y9GP01
uniprot id: A0A2Y9GT37
names: Similarity
messages: Belongs to the DPH4 family.

29088:LOC110580579
gene id: 29088:LOC110580579
uniprot id: A0A8M1MB22
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

29088:MED12L
gene id: 29088:MED12L
uniprot id: A0A2Y9GR18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

29088:TRIP10
gene id: 29088:TRIP10
uniprot id: A0A2Y9IC46
uniprot id: A0A2Y9IFR9
uniprot id: A0A2Y9IIT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNBP1 family.
messages: Cell membrane
messages: Lysosome
messages: Membrane
messages: cell cortex

29088:TSR3
gene id: 29088:TSR3
uniprot id: A0A2Y9HQM1
uniprot id: A0A2Y9HVW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ARTN
gene id: 29088:ARTN
uniprot id: A0A8M1M7C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

29088:NGB
gene id: 29088:NGB
uniprot id: A0A2Y9G8G0
names: Similarity
messages: Belongs to the globin family.

29088:SPP2
gene id: 29088:SPP2
uniprot id: A0A2Y9GA81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Could coordinate an aspect of bone turnover.
messages: Secreted

29088:LOC110589013
gene id: 29088:LOC110589013
uniprot id: A0A2Y9HU28
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

29088:LHFPL6
gene id: 29088:LHFPL6
uniprot id: A0A8M1M7X9
names: Subcellular Location Annotation
messages: Membrane

29088:MBTPS2
gene id: 29088:MBTPS2
uniprot id: A0A8M1M185
names: Similarity
messages: Belongs to the peptidase M50A family.

29088:SH2B2
gene id: 29088:SH2B2
uniprot id: A0A2Y9HX15
names: Similarity
messages: Belongs to the SH2B adapter family.

29088:AMOT
gene id: 29088:AMOT
uniprot id: A0A2Y9GSA5
names: Similarity
messages: Belongs to the angiomotin family.

29088:ESRP2
gene id: 29088:ESRP2
uniprot id: A0A2Y9IBU1
uniprot id: A0A8M1MWC4
uniprot id: A0A8M1MXJ4
uniprot id: A0A8M1MY47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESRP family.
messages: Nucleus

29088:GJD2
gene id: 29088:GJD2
uniprot id: A0A2Y9HNR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

29088:EXOC3L1
gene id: 29088:EXOC3L1
uniprot id: A0A2Y9IB50
names: Similarity
messages: Belongs to the SEC6 family.

29088:LOC110581467
gene id: 29088:LOC110581467
uniprot id: A0A2Y9H5T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

29088:NEUROD6
gene id: 29088:NEUROD6
uniprot id: A0A2Y9H1M0
uniprot id: A0A2Y9H1N2
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

29088:SGK2
gene id: 29088:SGK2
uniprot id: A0A2Y9GZG6
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:IFNE
gene id: 29088:IFNE
uniprot id: A0A2Y9HAF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

29088:LOC110590785
gene id: 29088:LOC110590785
uniprot id: A0A8M1M594
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

29088:SLC9A1
gene id: 29088:SLC9A1
uniprot id: A0A2Y9GKX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
messages: Membrane

29088:TMC2
gene id: 29088:TMC2
uniprot id: A0A2Y9H0F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

29088:FCF1
gene id: 29088:FCF1
uniprot id: A0A2Y9GAV4
uniprot id: A0A2Y9GBU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

29088:SLC7A8
gene id: 29088:SLC7A8
uniprot id: A0A2Y9HHE2
uniprot id: A0A2Y9HNN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Membrane

29088:CHRM3
gene id: 29088:CHRM3
uniprot id: A0A2Y9HJA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

29088:LOC110574609
gene id: 29088:LOC110574609
uniprot id: A0A2Y9GIP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

29088:RNF114
gene id: 29088:RNF114
uniprot id: A0A2Y9GUN9
names: Subunit
messages: Interacts with XAF1, the interaction increases XAF1 stability and proapoptotic effects, and may regulate IFN signaling.

29088:TMEM30A
gene id: 29088:TMEM30A
uniprot id: A0A2Y9HI07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC50/LEM3 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: secretory vesicle membrane

29088:LOC110577103
gene id: 29088:LOC110577103
uniprot id: A0A8M1M8Z2
names: Similarity
messages: Belongs to the intermediate filament family.

29088:CRYBG1
gene id: 29088:CRYBG1
uniprot id: A0A2Y9HAG7
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

29088:NELFE
gene id: 29088:NELFE
uniprot id: A0A2Y9HTC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NELF-E family.
messages: Chromosome
messages: Nucleus

29088:LOC110576901
gene id: 29088:LOC110576901
uniprot id: A0A2Y9GRH4
uniprot id: A0A2Y9GX17
names: Similarity
messages: Belongs to the serpin family.

29088:LOC110576499
gene id: 29088:LOC110576499
uniprot id: A0A2Y9GQA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:CENPN
gene id: 29088:CENPN
uniprot id: A0A2Y9I7Y5
uniprot id: A0A8M1MWF3
uniprot id: A0A8M1MY59
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

29088:ITPR1
gene id: 29088:ITPR1
uniprot id: A0A2Y9HG79
uniprot id: A0A2Y9HMK4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

29088:FAM131B
gene id: 29088:FAM131B
uniprot id: A0A2Y9HGA3
uniprot id: A0A8M1MQF3
names: Similarity
messages: Belongs to the FAM131 family.

29088:POLR2E
gene id: 29088:POLR2E
uniprot id: A0A2Y9I9X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
messages: Nucleus

29088:LOC110580213
gene id: 29088:LOC110580213
uniprot id: A0A8M1MGY6
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

29088:EML2
gene id: 29088:EML2
uniprot id: A0A8M1M0J3
uniprot id: A0A8M1M0U6
uniprot id: A0A8M1M4M6
uniprot id: A0A8M1M8A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EMAP family.
messages: cytoskeleton

29088:CCT6B
gene id: 29088:CCT6B
uniprot id: A0A2Y9I7I5
uniprot id: A0A2Y9I7T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

29088:FMO2
gene id: 29088:FMO2
uniprot id: A0A2Y9GLQ8
uniprot id: A0A8M1MEQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

29088:IARS1
gene id: 29088:IARS1
uniprot id: A0A2Y9HKA0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

29088:DCAF1
gene id: 29088:DCAF1
uniprot id: A0A8M1MJW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPRBP/DCAF1 family.
messages: Nucleus

29088:ZNF703
gene id: 29088:ZNF703
uniprot id: A0A2Y9GDU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

29088:LOC110590192
gene id: 29088:LOC110590192
uniprot id: A0A2Y9HYI0
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:PABPC1L
gene id: 29088:PABPC1L
uniprot id: A0A2Y9H6Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

29088:DLGAP4
gene id: 29088:DLGAP4
uniprot id: A0A2Y9GZB8
uniprot id: A0A2Y9GZH0
uniprot id: A0A2Y9GZH2
uniprot id: A0A2Y9GZH3
uniprot id: A0A2Y9H3X7
uniprot id: A0A2Y9H5V9
names: Similarity
messages: Belongs to the SAPAP family.

29088:CCNG1
gene id: 29088:CCNG1
uniprot id: A0A2Y9HUZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin G subfamily.
messages: May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.
messages: Nucleus

29088:CDC37L1
gene id: 29088:CDC37L1
uniprot id: A0A2Y9HKJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

29088:LOC110583604
gene id: 29088:LOC110583604
uniprot id: A0A2Y9HI47
names: Subcellular Location Annotation
messages: Nucleus

29088:OSGEPL1
gene id: 29088:OSGEPL1
uniprot id: A0A2Y9I3V7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Monomer.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

29088:FGD1
gene id: 29088:FGD1
uniprot id: A0A2Y9HUZ2
names: Subcellular Location Annotation
messages: cytoskeleton

29088:DDAH2
gene id: 29088:DDAH2
uniprot id: A0A2Y9HM16
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

29088:NPM3
gene id: 29088:NPM3
uniprot id: A0A2Y9HV12
names: Similarity
messages: Belongs to the nucleoplasmin family.

29088:DUSP2
gene id: 29088:DUSP2
uniprot id: A0A2Y9HTY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

29088:COPS3
gene id: 29088:COPS3
uniprot id: A0A2Y9HLV7
uniprot id: A0A2Y9HLY7
uniprot id: A0A8M1MWY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN3 family.
messages: Cytoplasm
messages: Nucleus

29088:SPTBN2
gene id: 29088:SPTBN2
uniprot id: A0A2Y9GPV8
uniprot id: A0A2Y9GQ00
uniprot id: A0A8M1MP29
uniprot id: A0A8M1MP34
names: Similarity
messages: Belongs to the spectrin family.

29088:UHRF2
gene id: 29088:UHRF2
uniprot id: A0A2Y9GG40
names: Subcellular Location Annotation
messages: Nucleus

29088:GRIA2
gene id: 29088:GRIA2
uniprot id: A0A2Y9HSH9
uniprot id: A0A2Y9HSZ5
uniprot id: A0A2Y9HT03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

29088:SLC35E3
gene id: 29088:SLC35E3
uniprot id: A0A2Y9G5H3
uniprot id: A0A2Y9G5X6
names: Subcellular Location Annotation
messages: Membrane

29088:AQP2
gene id: 29088:AQP2
uniprot id: A0A2Y9I9A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

29088:LOC110581171
gene id: 29088:LOC110581171
uniprot id: A0A2Y9HBD9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MAP4K5
gene id: 29088:MAP4K5
uniprot id: A0A8M1MTJ8
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

29088:LYG2
gene id: 29088:LYG2
uniprot id: A0A2Y9HZH3
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

29088:MPEG1
gene id: 29088:MPEG1
uniprot id: A0A2Y9GN34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPEG1 family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

29088:NUDT6
gene id: 29088:NUDT6
uniprot id: A0A2Y9GDJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Cytoplasm
messages: May contribute to the regulation of cell proliferation.
messages: Mitochondrion
messages: Monomer and homodimer.
messages: Nucleus

29088:SPRTN
gene id: 29088:SPRTN
uniprot id: A0A2Y9HJF2
uniprot id: A0A2Y9HQ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spartan family.
messages: Chromosome
messages: Nucleus

29088:CCDC90B
gene id: 29088:CCDC90B
uniprot id: A0A2Y9GSA2
uniprot id: A0A2Y9GSE7
names: Similarity
messages: Belongs to the CCDC90 family.

29088:HAPLN3
gene id: 29088:HAPLN3
uniprot id: A0A2Y9GAV2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:XG
gene id: 29088:XG
uniprot id: A0A8M1M128
names: Similarity
messages: Belongs to the CD99 family.

29088:CDH12
gene id: 29088:CDH12
uniprot id: A0A2Y9HIA2
uniprot id: A0A2Y9HIN8
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

29088:ACOT6
gene id: 29088:ACOT6
uniprot id: A0A2Y9G8G6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

29088:DUOXA1
gene id: 29088:DUOXA1
uniprot id: A0A2Y9HNE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

29088:WDR48
gene id: 29088:WDR48
uniprot id: A0A2Y9G2C0
uniprot id: A0A2Y9G4Y8
uniprot id: A0A8M1MRW7
uniprot id: A0A8M1MV39
uniprot id: A0A8M1MV44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR48 family.
messages: Endosome
messages: Late endosome

29088:STARD5
gene id: 29088:STARD5
uniprot id: A0A2Y9GE81
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

29088:PRR5
gene id: 29088:PRR5
uniprot id: A0A2Y9H762
names: Similarity
messages: Belongs to the PROTOR family.

29088:PICK1
gene id: 29088:PICK1
uniprot id: A0A2Y9GVJ9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
messages: cytoskeleton
messages: perinuclear region
messages: synaptosome

29088:ALOXE3
gene id: 29088:ALOXE3
uniprot id: A0A8M1MW79
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ACTL6A
gene id: 29088:ACTL6A
uniprot id: A0A2Y9H8F2
uniprot id: A0A2Y9HE58
uniprot id: A0A2Y9HF79
names: Similarity
messages: Belongs to the actin family.

29088:TRPV3
gene id: 29088:TRPV3
uniprot id: A0A2Y9IB91
uniprot id: A0A2Y9IDW9
names: Subcellular Location Annotation
messages: Membrane

29088:KCTD20
gene id: 29088:KCTD20
uniprot id: A0A2Y9GMD8
uniprot id: A0A2Y9GSY4
names: Subcellular Location Annotation
messages: Cytoplasm

29088:CWF19L2
gene id: 29088:CWF19L2
uniprot id: A0A8M1MRF2
names: Similarity
messages: Belongs to the CWF19 family.

29088:FOXE1
gene id: 29088:FOXE1
uniprot id: A0A2Y9H6U5
names: Subcellular Location Annotation
messages: Nucleus

29088:ITGB6
gene id: 29088:ITGB6
uniprot id: A0A2Y9I382
uniprot id: A0A8M1M899
uniprot id: A0A8M1ME05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

29088:DNAI7
gene id: 29088:DNAI7
uniprot id: A0A2Y9H3H9
uniprot id: A0A2Y9H3K5
names: Similarity
messages: Belongs to the DNAI7 family.

29088:CLUH
gene id: 29088:CLUH
uniprot id: A0A2Y9I744
uniprot id: A0A2Y9I7F0
uniprot id: A0A2Y9IBV2
uniprot id: A0A2Y9IEJ8
uniprot id: A0A8M1MUI4
uniprot id: A0A8M1MUI5
uniprot id: A0A8M1MWB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: Cytoplasmic granule
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.

29088:KCNN4
gene id: 29088:KCNN4
uniprot id: A0A2Y9GFL1
names: Subcellular Location Annotation
messages: Membrane

29088:AMPD1
gene id: 29088:AMPD1
uniprot id: A0A2Y9H2F5
uniprot id: A0A8M1M847
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

29088:CLSTN3
gene id: 29088:CLSTN3
uniprot id: A0A8M1MAR1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

29088:SLC9A8
gene id: 29088:SLC9A8
uniprot id: A0A2Y9GQU9
uniprot id: A0A8M1MMG3
uniprot id: A0A8M1MPF5
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

29088:ARRB2
gene id: 29088:ARRB2
uniprot id: A0A2Y9HL08
names: Similarity
messages: Belongs to the arrestin family.

29088:DNAJC22
gene id: 29088:DNAJC22
uniprot id: A0A2Y9I9H2
names: Function
names: Subcellular Location Annotation
messages: May function as a co-chaperone.
messages: Membrane

29088:WARS1
gene id: 29088:WARS1
uniprot id: A0A2Y9GCP9
uniprot id: A0A8M1ML57
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

29088:CENPT
gene id: 29088:CENPT
uniprot id: A0A2Y9I5W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-T/CNN1 family.
messages: Nucleus
messages: kinetochore

29088:LOC110586292
gene id: 29088:LOC110586292
uniprot id: A0A8M1MNW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA3 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Membrane
messages: Mitochondrion inner membrane

29088:PRKRIP1
gene id: 29088:PRKRIP1
uniprot id: A0A2Y9HWU7
names: Similarity
messages: Belongs to the PRKRIP1 family.

29088:MMP11
gene id: 29088:MMP11
uniprot id: A0A2Y9GWM4
names: Similarity
messages: Belongs to the peptidase M10A family.

29088:LOC110585318
gene id: 29088:LOC110585318
uniprot id: A0A8M1MLP3
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6A family.

29088:LOC110576280
gene id: 29088:LOC110576280
uniprot id: A0A8M1MRT3
names: Function
names: Similarity
names: Subunit
messages: Component of the 40S subunit of the ribosome.
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Ribosomal protein S27a is part of the 40S ribosomal subunit.

29088:RFT1
gene id: 29088:RFT1
uniprot id: A0A2Y9HN51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: May be involved in N-linked oligosaccharide assembly.
messages: Membrane

29088:MRPL13
gene id: 29088:MRPL13
uniprot id: A0A2Y9GXZ1
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

29088:MDFIC
gene id: 29088:MDFIC
uniprot id: A0A2Y9I080
names: Similarity
messages: Belongs to the MDFI family.

29088:TADA1
gene id: 29088:TADA1
uniprot id: A0A2Y9GH85
uniprot id: A0A2Y9GHA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TADA1 family.
messages: Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9.
messages: Nucleus
messages: Probably involved in transcriptional regulation.

29088:CLDN9
gene id: 29088:CLDN9
uniprot id: A0A2Y9HQR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

29088:PLP2
gene id: 29088:PLP2
uniprot id: A0A8M1M1Z3
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110591478
gene id: 29088:LOC110591478
uniprot id: A0A2Y9I743
uniprot id: A0A8M1M4E8
uniprot id: A0A8M1M822
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

29088:MMP15
gene id: 29088:MMP15
uniprot id: A0A8M1MVV3
names: Similarity
messages: Belongs to the peptidase M10A family.

29088:EPB42
gene id: 29088:EPB42
uniprot id: A0A2Y9HH65
uniprot id: A0A2Y9HH68
uniprot id: A0A2Y9HHG5
uniprot id: A0A2Y9HNC4
uniprot id: A0A2Y9HNR9
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

29088:ETV3L
gene id: 29088:ETV3L
uniprot id: A0A2Y9GEX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

29088:MXRA8
gene id: 29088:MXRA8
uniprot id: A0A2Y9GIW6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:MSL3
gene id: 29088:MSL3
uniprot id: A0A8M1M633
uniprot id: A0A8M1M9X4
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110570779
gene id: 29088:LOC110570779
uniprot id: A0A8M1MF65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
messages: Cytoplasm

29088:SEMA3C
gene id: 29088:SEMA3C
uniprot id: A0A2Y9H7D1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:PPM1K
gene id: 29088:PPM1K
uniprot id: A0A2Y9I914
names: Similarity
messages: Belongs to the PP2C family.

29088:UBN2
gene id: 29088:UBN2
uniprot id: A0A2Y9H9Y9
uniprot id: A0A2Y9HFY9
names: Similarity
messages: Belongs to the ubinuclein family.

29088:RAD21L1
gene id: 29088:RAD21L1
uniprot id: A0A2Y9H4P0
uniprot id: A0A8M1MNV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

29088:APOE
gene id: 29088:APOE
uniprot id: A0A7F3QY86
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

29088:MAT2B
gene id: 29088:MAT2B
uniprot id: A0A2Y9HQ76
uniprot id: A0A2Y9HWL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
messages: Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.
messages: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.

29088:BACE1
gene id: 29088:BACE1
uniprot id: A0A2Y9HR86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Membrane
messages: Membrane raft
messages: Recycling endosome
messages: trans-Golgi network

29088:APOC1
gene id: 29088:APOC1
uniprot id: A0A2Y9GD53
uniprot id: A0A2Y9GG65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C1 family.
messages: Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
messages: Secreted

29088:LOC110594038
gene id: 29088:LOC110594038
uniprot id: A0A8M1M589
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110576433
gene id: 29088:LOC110576433
uniprot id: A0A2Y9GTW8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:PARP2
gene id: 29088:PARP2
uniprot id: A0A2Y9HH57
uniprot id: A0A2Y9HNB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

29088:ABI1
gene id: 29088:ABI1
uniprot id: A0A2Y9GU41
uniprot id: A0A2Y9GU45
uniprot id: A0A2Y9GU97
uniprot id: A0A2Y9GUA1
uniprot id: A0A2Y9GUA2
uniprot id: A0A2Y9GYD3
uniprot id: A0A2Y9GYD8
uniprot id: A0A2Y9H018
uniprot id: A0A2Y9H023
uniprot id: A0A8M1MC86
uniprot id: A0A8M1MCD5
uniprot id: A0A8M1MEG1
uniprot id: A0A8M1MFV3
uniprot id: A0A8M1MKS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

29088:GOT1
gene id: 29088:GOT1
uniprot id: A0A2Y9I1W8
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

29088:PXMP2
gene id: 29088:PXMP2
uniprot id: A0A2Y9HF55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

29088:SLC39A5
gene id: 29088:SLC39A5
uniprot id: A0A2Y9H068
names: Subcellular Location Annotation
messages: Membrane

29088:RETN
gene id: 29088:RETN
uniprot id: A0A2Y9IAX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistin/FIZZ family.
messages: Secreted

29088:ZC3H12C
gene id: 29088:ZC3H12C
uniprot id: A0A8M1MPG3
names: Similarity
messages: Belongs to the ZC3H12 family.

29088:ALDH4A1
gene id: 29088:ALDH4A1
uniprot id: A0A2Y9GJC8
uniprot id: A0A8M1M7S3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

29088:ABCG2
gene id: 29088:ABCG2
uniprot id: A0A2Y9I231
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion membrane

29088:IL17F
gene id: 29088:IL17F
uniprot id: A0A2Y9H7V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

29088:UCK2
gene id: 29088:UCK2
uniprot id: A0A2Y9HR51
uniprot id: A0A8M1MHZ4
names: Similarity
names: Subunit
messages: Belongs to the uridine kinase family.
messages: Homotetramer.

29088:P2RY8
gene id: 29088:P2RY8
uniprot id: A0A8M1M3W2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:CTBP2
gene id: 29088:CTBP2
uniprot id: A0A2Y9I715
uniprot id: A0A2Y9IDM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

29088:DDR2
gene id: 29088:DDR2
uniprot id: A0A2Y9HQS7
names: Subcellular Location Annotation
messages: Membrane

29088:ACE
gene id: 29088:ACE
uniprot id: A0A2Y9G4W0
uniprot id: A0A2Y9G4X1
uniprot id: A0A8M1MV05
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.

29088:THPO
gene id: 29088:THPO
uniprot id: A0A2Y9H938
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPO/TPO family.
messages: Secreted

29088:SLC18A2
gene id: 29088:SLC18A2
uniprot id: A0A2Y9HZT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

29088:LDB1
gene id: 29088:LDB1
uniprot id: A0A2Y9HUM9
uniprot id: A0A2Y9HUN3
uniprot id: A0A2Y9I0Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDB family.
messages: Nucleus

29088:TAAR5
gene id: 29088:TAAR5
uniprot id: A0A2Y9HIQ0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:SEPTIN4
gene id: 29088:SEPTIN4
uniprot id: A0A2Y9I8U8
uniprot id: A0A8M1MUY4
uniprot id: A0A8M1MWP7
uniprot id: A0A8M1MZ80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

29088:IFT57
gene id: 29088:IFT57
uniprot id: A0A2Y9HEL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT57 family.
messages: cilium basal body

29088:LUC7L3
gene id: 29088:LUC7L3
uniprot id: A0A2Y9I6N6
uniprot id: A0A8M1MU19
names: Similarity
messages: Belongs to the Luc7 family.

29088:MID2
gene id: 29088:MID2
uniprot id: A0A2Y9G4L8
uniprot id: A0A2Y9G881
names: Subcellular Location Annotation
messages: cytoskeleton

29088:LARS2
gene id: 29088:LARS2
uniprot id: A0A2Y9GL97
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

29088:JUND
gene id: 29088:JUND
uniprot id: A0A2Y9GI17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

29088:PRKAB1
gene id: 29088:PRKAB1
uniprot id: A0A2Y9IA28
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

29088:PNPLA1
gene id: 29088:PNPLA1
uniprot id: A0A2Y9GM88
uniprot id: A0A2Y9GMD2
uniprot id: A0A2Y9GR82
uniprot id: A0A2Y9GSX9
uniprot id: A0A8M1MHQ5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:TMEM242
gene id: 29088:TMEM242
uniprot id: A0A2Y9HAJ8
uniprot id: A0A2Y9HGL6
uniprot id: A0A2Y9HH91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

29088:LOC110585299
gene id: 29088:LOC110585299
uniprot id: A0A2Y9HNJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LRRC8D
gene id: 29088:LRRC8D
uniprot id: A0A2Y9H935
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

29088:GLI2
gene id: 29088:GLI2
uniprot id: A0A8M1M9J8
uniprot id: A0A8M1MDU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

29088:DMRT3
gene id: 29088:DMRT3
uniprot id: A0A8M1MS43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

29088:CACNB1
gene id: 29088:CACNB1
uniprot id: A0A2Y9I7N2
uniprot id: A0A2Y9I8G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Membrane
messages: sarcolemma

29088:MRPS7
gene id: 29088:MRPS7
uniprot id: A0A2Y9GCF5
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

29088:TAF13
gene id: 29088:TAF13
uniprot id: A0A2Y9H2G3
names: Subcellular Location Annotation
messages: Nucleus

29088:SLC25A37
gene id: 29088:SLC25A37
uniprot id: A0A2Y9HXC1
uniprot id: A0A2Y9HYW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:EMC3
gene id: 29088:EMC3
uniprot id: A0A2Y9HM50
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

29088:LOC110589046
gene id: 29088:LOC110589046
uniprot id: A0A8M1MQI8
uniprot id: A0A8M1MQJ5
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

29088:SLC30A5
gene id: 29088:SLC30A5
uniprot id: A0A2Y9HWW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Membrane
messages: trans-Golgi network membrane

29088:BLOC1S6
gene id: 29088:BLOC1S6
uniprot id: A0A2Y9HH29
names: Function
names: Similarity
messages: Belongs to the BLOC1S6 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.

29088:PRKCA
gene id: 29088:PRKCA
uniprot id: A0A2Y9G7H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

29088:PPA2
gene id: 29088:PPA2
uniprot id: A0A2Y9GAP3
names: Similarity
messages: Belongs to the PPase family.

29088:LOC110575479
gene id: 29088:LOC110575479
uniprot id: A0A8M1M0Q0
uniprot id: A0A8M1M393
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

29088:PALM3
gene id: 29088:PALM3
uniprot id: A0A2Y9I9Q6
uniprot id: A0A2Y9IE61
names: Similarity
messages: Belongs to the paralemmin family.

29088:KYAT3
gene id: 29088:KYAT3
uniprot id: A0A2Y9H293
uniprot id: A0A2Y9H2B4
uniprot id: A0A2Y9H2D1
uniprot id: A0A2Y9H8V6
names: Subunit
messages: Homodimer.

29088:RPS20
gene id: 29088:RPS20
uniprot id: A0A2Y9GXD8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

29088:TSPAN3
gene id: 29088:TSPAN3
uniprot id: A0A2Y9HCT6
uniprot id: A0A8M1MTD5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:ITPKC
gene id: 29088:ITPKC
uniprot id: A0A2Y9HYF3
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

29088:FAM83B
gene id: 29088:FAM83B
uniprot id: A0A2Y9HEE2
names: Similarity
messages: Belongs to the FAM83 family.

29088:PYCR3
gene id: 29088:PYCR3
uniprot id: A0A2Y9GY99
uniprot id: A0A8M1MH39
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

29088:GRID1
gene id: 29088:GRID1
uniprot id: A0A8M1MNU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

29088:GCLC
gene id: 29088:GCLC
uniprot id: A0A2Y9HD99
uniprot id: A0A2Y9HEH7
uniprot id: A0A8M1MJP7
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

29088:UCHL1
gene id: 29088:UCHL1
uniprot id: A0A2Y9I727
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C12 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:FAM216A
gene id: 29088:FAM216A
uniprot id: A0A2Y9HR66
names: Similarity
messages: Belongs to the FAM216 family.

29088:TENT5C
gene id: 29088:TENT5C
uniprot id: A0A2Y9H2K8
names: Similarity
messages: Belongs to the TENT family.

29088:NAGA
gene id: 29088:NAGA
uniprot id: A0A2Y9GW12
uniprot id: A0A2Y9GW56
uniprot id: A0A8M1MD31
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

29088:ABRAXAS1
gene id: 29088:ABRAXAS1
uniprot id: A0A2Y9I6Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abraxas subfamily.
messages: Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.
messages: Nucleus

29088:PIGU
gene id: 29088:PIGU
uniprot id: A0A2Y9GZF1
uniprot id: A0A2Y9H415
uniprot id: A0A8M1MPF9
uniprot id: A0A8M1MWP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:LOC110591664
gene id: 29088:LOC110591664
uniprot id: A0A8M1MB86
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Component of the 40S small ribosomal subunit.

29088:EGFL8
gene id: 29088:EGFL8
uniprot id: A0A2Y9HSM1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:METTL26
gene id: 29088:METTL26
uniprot id: A0A2Y9HQG2
uniprot id: A0A2Y9HVD4
uniprot id: A0A2Y9HWX1
uniprot id: A0A8M1MAS6
uniprot id: A0A8M1MB05
names: Similarity
messages: Belongs to the UPF0585 family.

29088:CENPS
gene id: 29088:CENPS
uniprot id: A0A2Y9GKS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.
messages: Nucleus
messages: kinetochore

29088:DDX5
gene id: 29088:DDX5
uniprot id: A0A8M1MXP3
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.

29088:OGFOD1
gene id: 29088:OGFOD1
uniprot id: A0A2Y9ID13
uniprot id: A0A2Y9IFS4
uniprot id: A0A8M1MVY3
names: Similarity
messages: Belongs to the TPA1 family.

29088:SGCE
gene id: 29088:SGCE
uniprot id: A0A2Y9H197
uniprot id: A0A8M1MY50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan alpha/epsilon family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: Golgi apparatus
messages: cytoskeleton
messages: dendrite
messages: sarcolemma

29088:CEP55
gene id: 29088:CEP55
uniprot id: A0A2Y9I2B3
names: Subcellular Location Annotation
messages: Cytoplasm

29088:ADA2
gene id: 29088:ADA2
uniprot id: A0A2Y9H3U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

29088:ZSCAN29
gene id: 29088:ZSCAN29
uniprot id: A0A2Y9HGW0
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

29088:SUPT4H1
gene id: 29088:SUPT4H1
uniprot id: A0A8M1MZ34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.
messages: Nucleus

29088:LOC110594264
gene id: 29088:LOC110594264
uniprot id: A0A2Y9ICP2
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: According to a well-established model, RNF168 cannot initiate H2A 'Lys-63'-linked ubiquitination and is recruited following RNF8-dependent histone ubiquitination to amplify H2A 'Lys-63'-linked ubiquitination. However, other data suggest that RNF168 is the priming ubiquitin ligase by mediating monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub respectively). These data suggest that RNF168 might be recruited to DSBs sites in a RNF8-dependent manner by binding to non-histone proteins ubiquitinated via 'Lys-63'-linked and initiates monoubiquitination of H2A, which is then amplified by RNF8. Additional evidences are however required to confirm these data.
messages: Belongs to the RNF168 family.
messages: E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recruited at DNA interstrand cross-links (ICLs) sites and promotes accumulation of 'Lys-63'-linked ubiquitination of histones H2A and H2AX, leading to recruitment of FAAP20 and Fanconi anemia (FA) complex, followed by interstrand cross-link repair. H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Also involved in class switch recombination in immune system, via its role in regulation of DSBs repair. Following DNA damage, promotes the ubiquitination and degradation of JMJD2A/KDM4A in collaboration with RNF8, leading to unmask H4K20me2 mark and promote the recruitment of TP53BP1 at DNA damage sites. Not able to initiate 'Lys-63'-linked ubiquitination in vitro; possibly due to partial occlusion of the UBE2N/UBC13-binding region. Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with UBE2N/UBC13.
messages: Nucleus
messages: Sumoylated with SUMO1 by PIAS4 in response to double-strand breaks (DSBs).
messages: The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).
messages: Ubiquitinated.

29088:NAPSA
gene id: 29088:NAPSA
uniprot id: A0A2Y9GGF6
names: Similarity
messages: Belongs to the peptidase A1 family.

29088:NPFFR1
gene id: 29088:NPFFR1
uniprot id: A0A2Y9HV35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

29088:LOC110576330
gene id: 29088:LOC110576330
uniprot id: A0A2Y9GPN0
uniprot id: A0A2Y9GTI0
uniprot id: A0A8M1MPJ9
uniprot id: A0A8M1MPK2
uniprot id: A0A8M1MSU1
uniprot id: A0A8M1MXZ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

29088:LOC110579666
gene id: 29088:LOC110579666
uniprot id: A0A2Y9H0F5
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

29088:SCGN
gene id: 29088:SCGN
uniprot id: A0A2Y9HLY6
names: Subcellular Location Annotation
messages: secretory vesicle membrane

29088:CCDC85A
gene id: 29088:CCDC85A
uniprot id: A0A2Y9HYX8
uniprot id: A0A2Y9HZ28
uniprot id: A0A2Y9HZB7
uniprot id: A0A2Y9I3V4
uniprot id: A0A2Y9I5R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

29088:SOAT1
gene id: 29088:SOAT1
uniprot id: A0A2Y9GH71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:NNT
gene id: 29088:NNT
uniprot id: A0A8M1MIC6
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

29088:RIOK1
gene id: 29088:RIOK1
uniprot id: A0A2Y9HS65
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

29088:LOC110579510
gene id: 29088:LOC110579510
uniprot id: A0A8M1MVW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

29088:TGFB2
gene id: 29088:TGFB2
uniprot id: A0A2Y9HVZ6
uniprot id: A0A8M1MGL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

29088:LOC110570711
gene id: 29088:LOC110570711
uniprot id: A0A2Y9G5X4
names: Similarity
messages: Belongs to the PRR23 family.

29088:ANKRD34B
gene id: 29088:ANKRD34B
uniprot id: A0A2Y9I1E9
names: Similarity
messages: Belongs to the ANKRD34 family.

29088:SERPINA4
gene id: 29088:SERPINA4
uniprot id: A0A2Y9G8N5
names: Similarity
messages: Belongs to the serpin family.

29088:LOC110570393
gene id: 29088:LOC110570393
uniprot id: A0A2Y9G8J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
messages: Secreted

29088:LOC110590877
gene id: 29088:LOC110590877
uniprot id: A0A2Y9I575
names: Subcellular Location Annotation
messages: Nucleus

29088:TNFSF4
gene id: 29088:TNFSF4
uniprot id: A0A2Y9GGP5
names: Similarity
messages: Belongs to the tumor necrosis factor family.

29088:TAGLN3
gene id: 29088:TAGLN3
uniprot id: A0A2Y9H8W5
names: Similarity
messages: Belongs to the calponin family.

29088:LOC110573347
gene id: 29088:LOC110573347
uniprot id: A0A2Y9GEK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:B3GALT1
gene id: 29088:B3GALT1
uniprot id: A0A2Y9IC41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:MRPL49
gene id: 29088:MRPL49
uniprot id: A0A2Y9GPR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

29088:FAM126B
gene id: 29088:FAM126B
uniprot id: A0A2Y9IAV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM126 family.
messages: Cell membrane
messages: Membrane
messages: cytosol

29088:MEIG1
gene id: 29088:MEIG1
uniprot id: A0A2Y9HL89
names: Function
names: Similarity
messages: Belongs to the MEIG1 family.
messages: Essential for spermiogenesis.

29088:NKX2-6
gene id: 29088:NKX2-6
uniprot id: A0A2Y9HXT0
names: Subcellular Location Annotation
messages: Nucleus

29088:RWDD3
gene id: 29088:RWDD3
uniprot id: A0A2Y9H7H3
uniprot id: A0A2Y9H950
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:THUMPD3
gene id: 29088:THUMPD3
uniprot id: A0A2Y9HMH1
uniprot id: A0A8M1MV53
uniprot id: A0A8M1MWH5
names: Similarity
messages: Belongs to the methyltransferase superfamily.

29088:LOC110586880
gene id: 29088:LOC110586880
uniprot id: A0A2Y9HME5
names: Subcellular Location Annotation
messages: Nucleus

29088:DOCK8
gene id: 29088:DOCK8
uniprot id: A0A2Y9HKM8
names: Similarity
messages: Belongs to the DOCK family.

29088:PTPN21
gene id: 29088:PTPN21
uniprot id: A0A2Y9GBL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

29088:HYAL1
gene id: 29088:HYAL1
uniprot id: A0A2Y9GY06
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

29088:ADCYAP1R1
gene id: 29088:ADCYAP1R1
uniprot id: A0A2Y9H152
uniprot id: A0A2Y9H199
uniprot id: A0A2Y9H1B4
uniprot id: A0A2Y9H7Q1
names: Subcellular Location Annotation
messages: Membrane

29088:DGLUCY
gene id: 29088:DGLUCY
uniprot id: A0A2Y9G9D9
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

29088:TMOD1
gene id: 29088:TMOD1
uniprot id: A0A2Y9H5C4
names: Subcellular Location Annotation
messages: cytoskeleton

29088:MAGI3
gene id: 29088:MAGI3
uniprot id: A0A2Y9H298
uniprot id: A0A8M1M9Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane
messages: tight junction

29088:RPS3A
gene id: 29088:RPS3A
uniprot id: A0A2Y9HSX7
uniprot id: A0A8M1M4W2
uniprot id: A0A8M1M8I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Binds with high affinity to IPO4. Interacts with DDIT3.
messages: Cytoplasm
messages: May play a role during erythropoiesis through regulation of transcription factor DDIT3.
messages: Nucleus

29088:NDRG4
gene id: 29088:NDRG4
uniprot id: A0A2Y9I7R7
uniprot id: A0A2Y9I7S8
uniprot id: A0A8M1M0G1
uniprot id: A0A8M1M0R3
uniprot id: A0A8M1M306
uniprot id: A0A8M1M4J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDRG family.
messages: cytosol

29088:DLC1
gene id: 29088:DLC1
uniprot id: A0A2Y9HK42
uniprot id: A0A2Y9HKE7
uniprot id: A0A8M1M4R6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.
messages: Interacts with EF1A1, facilitates EF1A1 distribution to the membrane periphery and ruffles upon growth factor stimulation and suppresses cell migration.
messages: Membrane
messages: focal adhesion

29088:FADS3
gene id: 29088:FADS3
uniprot id: A0A2Y9GMZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Endoplasmic reticulum membrane

29088:METTL14
gene id: 29088:METTL14
uniprot id: A0A2Y9GS72
names: Similarity
messages: Belongs to the MT-A70-like family.

29088:CHD3
gene id: 29088:CHD3
uniprot id: A0A8M1MVB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

29088:GPRC5B
gene id: 29088:GPRC5B
uniprot id: A0A2Y9HUS6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:ITIH5
gene id: 29088:ITIH5
uniprot id: A0A2Y9HKV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

29088:MMRN1
gene id: 29088:MMRN1
uniprot id: A0A2Y9I292
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:B4GAT1
gene id: 29088:B4GAT1
uniprot id: A0A2Y9GSF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 49 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:SYT1
gene id: 29088:SYT1
uniprot id: A0A2Y9G5C2
uniprot id: A0A2Y9G7U3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

29088:LOC110575856
gene id: 29088:LOC110575856
uniprot id: A0A2Y9GMS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MAPRE2
gene id: 29088:MAPRE2
uniprot id: A0A2Y9GRB7
uniprot id: A0A2Y9GV75
uniprot id: A0A2Y9GWV4
uniprot id: A0A8M1MUI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.
messages: cytoskeleton

29088:MSANTD3
gene id: 29088:MSANTD3
uniprot id: A0A2Y9H5W2
names: Similarity
messages: Belongs to the MSANTD3 family.

29088:POLR2A
gene id: 29088:POLR2A
uniprot id: A0A2Y9HEK3
uniprot id: A0A8M1MVQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

29088:LOC123326402
gene id: 29088:LOC123326402
uniprot id: A0A8M1MQL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ependymin family.
messages: Binds anionic lipids and gangliosides at acidic pH.
messages: Lysosome lumen

29088:URAD
gene id: 29088:URAD
uniprot id: A0A2Y9G4G4
names: Function
names: Similarity
messages: Belongs to the OHCU decarboxylase family.
messages: Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.

29088:LOC110578582
gene id: 29088:LOC110578582
uniprot id: A0A2Y9H171
names: Similarity
messages: Belongs to the S-100 family.

29088:LOC110570579
gene id: 29088:LOC110570579
uniprot id: A0A8M1MIH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

29088:STAR
gene id: 29088:STAR
uniprot id: A0A2Y9GDN1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion
messages: Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.

29088:GNS
gene id: 29088:GNS
uniprot id: A0A2Y9G961
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

29088:SMAD5
gene id: 29088:SMAD5
uniprot id: A0A2Y9I186
uniprot id: A0A8M1MPN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

29088:GOLGA5
gene id: 29088:GOLGA5
uniprot id: A0A2Y9G8R0
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.
messages: Membrane

29088:MFSD5
gene id: 29088:MFSD5
uniprot id: A0A2Y9GX83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Cell membrane
messages: Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
messages: Membrane

29088:DLX1
gene id: 29088:DLX1
uniprot id: A0A2Y9I4J5
names: Subcellular Location Annotation
messages: Nucleus

29088:TMED3
gene id: 29088:TMED3
uniprot id: A0A2Y9GBD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

29088:AQP5
gene id: 29088:AQP5
uniprot id: A0A2Y9IGD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

29088:ASL
gene id: 29088:ASL
uniprot id: A0A2Y9HWN4
uniprot id: A0A8M1MDC4
uniprot id: A0A8M1MJK1
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

29088:PPIC
gene id: 29088:PPIC
uniprot id: A0A2Y9I0L2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

29088:AK5
gene id: 29088:AK5
uniprot id: A0A2Y9G6M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family.
messages: Cytoplasm

29088:CDC42EP1
gene id: 29088:CDC42EP1
uniprot id: A0A2Y9GVQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

29088:NAIF1
gene id: 29088:NAIF1
uniprot id: A0A2Y9H6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

29088:HS3ST4
gene id: 29088:HS3ST4
uniprot id: A0A2Y9I3V2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

29088:LOC110584749
gene id: 29088:LOC110584749
uniprot id: A0A8M1M1Q6
names: Similarity
messages: Belongs to the costars family.

29088:ALDH5A1
gene id: 29088:ALDH5A1
uniprot id: A0A2Y9HLM1
uniprot id: A0A2Y9HS75
uniprot id: A0A2Y9HTD4
uniprot id: A0A8M1MJM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
messages: Homotetramer.
messages: Mitochondrion

29088:DLGAP3
gene id: 29088:DLGAP3
uniprot id: A0A2Y9GJM1
names: Similarity
messages: Belongs to the SAPAP family.

29088:MRGPRF
gene id: 29088:MRGPRF
uniprot id: A0A2Y9GNV2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:UNC5D
gene id: 29088:UNC5D
uniprot id: A0A2Y9GDM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

29088:CCDC85C
gene id: 29088:CCDC85C
uniprot id: A0A8M1MT61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

29088:LOC110584359
gene id: 29088:LOC110584359
uniprot id: A0A2Y9HEJ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:CEP19
gene id: 29088:CEP19
uniprot id: A0A2Y9H9F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body
messages: spindle pole

29088:LOC110585340
gene id: 29088:LOC110585340
uniprot id: A0A2Y9HHW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:NXPE3
gene id: 29088:NXPE3
uniprot id: A0A2Y9H8N8
uniprot id: A0A2Y9H8T2
names: Similarity
messages: Belongs to the NXPE family.

29088:COPS2
gene id: 29088:COPS2
uniprot id: A0A2Y9HDB2
uniprot id: A0A2Y9HJW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN2 family.
messages: Cytoplasm
messages: Nucleus

29088:PTGIR
gene id: 29088:PTGIR
uniprot id: A0A2Y9GFQ7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:TFEB
gene id: 29088:TFEB
uniprot id: A0A2Y9H7C0
uniprot id: A0A2Y9HE77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

29088:CPEB2
gene id: 29088:CPEB2
uniprot id: A0A2Y9G7T8
uniprot id: A0A2Y9G814
uniprot id: A0A2Y9G862
uniprot id: A0A2Y9G866
uniprot id: A0A2Y9GAG8
uniprot id: A0A2Y9GAH7
uniprot id: A0A2Y9GBG1
uniprot id: A0A2Y9GBG4
uniprot id: A0A8M1M519
uniprot id: A0A8M1M5C2
uniprot id: A0A8M1M7G3
uniprot id: A0A8M1M8Y0
names: Similarity
messages: Belongs to the RRM CPEB family.

29088:SLC18A1
gene id: 29088:SLC18A1
uniprot id: A0A2Y9HSP8
uniprot id: A0A2Y9HSQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

29088:LOC110574521
gene id: 29088:LOC110574521
uniprot id: A0A2Y9GLP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SERINC4
gene id: 29088:SERINC4
uniprot id: A0A8M1MK51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

29088:CPEB1
gene id: 29088:CPEB1
uniprot id: A0A2Y9GB45
uniprot id: A0A2Y9GB93
uniprot id: A0A8M1ML72
names: Similarity
messages: Belongs to the RRM CPEB family.

29088:LOC110594300
gene id: 29088:LOC110594300
uniprot id: A0A2Y9IJI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft

29088:ATP2A3
gene id: 29088:ATP2A3
uniprot id: A0A2Y9IFT7
uniprot id: A0A8M1MZB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

29088:ATP11B
gene id: 29088:ATP11B
uniprot id: A0A2Y9H9A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

29088:SOX21
gene id: 29088:SOX21
uniprot id: A0A2Y9HIN4
uniprot id: A0A8M1M5N9
names: Subcellular Location Annotation
messages: Nucleus

29088:P2RX7
gene id: 29088:P2RX7
uniprot id: A0A2Y9HWJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P2X receptor family.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

29088:TMEM184C
gene id: 29088:TMEM184C
uniprot id: A0A2Y9HSH8
names: Subcellular Location Annotation
messages: Membrane

29088:SLC13A2
gene id: 29088:SLC13A2
uniprot id: A0A2Y9I8E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

29088:TMEM47
gene id: 29088:TMEM47
uniprot id: A0A2Y9GDS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

29088:LOC110574524
gene id: 29088:LOC110574524
uniprot id: A0A2Y9GIG8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ABL2
gene id: 29088:ABL2
uniprot id: A0A2Y9GH84
uniprot id: A0A8M1MDE0
uniprot id: A0A8M1MDI8
uniprot id: A0A8M1MFK3
uniprot id: A0A8M1MGZ5
uniprot id: A0A8M1MH00
uniprot id: A0A8M1MM23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

29088:DDX21
gene id: 29088:DDX21
uniprot id: A0A2Y9HUA6
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

29088:TRAP1
gene id: 29088:TRAP1
uniprot id: A0A2Y9HPZ6
names: Similarity
messages: Belongs to the heat shock protein 90 family.

29088:KCNMB3
gene id: 29088:KCNMB3
uniprot id: A0A2Y9HF64
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

29088:COL4A3
gene id: 29088:COL4A3
uniprot id: A0A2Y9GHL1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

29088:EDN3
gene id: 29088:EDN3
uniprot id: A0A2Y9G357
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

29088:BTG2
gene id: 29088:BTG2
uniprot id: A0A2Y9GWP7
names: Similarity
messages: Belongs to the BTG family.

29088:ATG101
gene id: 29088:ATG101
uniprot id: A0A2Y9IDT3
names: Similarity
messages: Belongs to the ATG101 family.

29088:LOC110585886
gene id: 29088:LOC110585886
uniprot id: A0A8M1M5D6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

29088:LOC110593941
gene id: 29088:LOC110593941
uniprot id: A0A2Y9IBH9
uniprot id: A0A2Y9II69
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with EIF4G1. Associates with ribosomes.
messages: nucleoplasm

29088:TLR8
gene id: 29088:TLR8
uniprot id: A0A2Y9GKF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

29088:PPP5C
gene id: 29088:PPP5C
uniprot id: A0A2Y9GCX0
uniprot id: A0A8M1M4N6
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

29088:MED23
gene id: 29088:MED23
uniprot id: A0A2Y9HBC5
uniprot id: A0A8M1MIE9
uniprot id: A0A8M1MIF2
uniprot id: A0A8M1MKH0
uniprot id: A0A8M1MLT3
uniprot id: A0A8M1MSE2
uniprot id: A0A8M1MSE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 23 family.
messages: Nucleus

29088:FBXO32
gene id: 29088:FBXO32
uniprot id: A0A2Y9GYY2
uniprot id: A0A8M1MH28
names: Subcellular Location Annotation
messages: Nucleus

29088:INO80
gene id: 29088:INO80
uniprot id: A0A2Y9HP86
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

29088:SOX9
gene id: 29088:SOX9
uniprot id: A0A2Y9G5I7
uniprot id: A0A8M1MU83
names: Subcellular Location Annotation
messages: Nucleus

29088:SMAD3
gene id: 29088:SMAD3
uniprot id: A0A2Y9HII2
uniprot id: A0A8M1MIL7
uniprot id: A0A8M1MLZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

29088:SPX
gene id: 29088:SPX
uniprot id: A0A2Y9HA22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spexin family.
messages: Secreted

29088:DCLRE1B
gene id: 29088:DCLRE1B
uniprot id: A0A2Y9H2X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

29088:LOC110585737
gene id: 29088:LOC110585737
uniprot id: A0A2Y9HIR6
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:LOC110575130
gene id: 29088:LOC110575130
uniprot id: A0A2Y9GKJ1
names: Subcellular Location Annotation
messages: Nucleus

29088:PSENEN
gene id: 29088:PSENEN
uniprot id: A0A2Y9HYD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEN-2 family.
messages: Golgi stack membrane
messages: Membrane

29088:VPS13D
gene id: 29088:VPS13D
uniprot id: A0A8M1MBA7
names: Similarity
messages: Belongs to the VPS13 family.

29088:METTL8
gene id: 29088:METTL8
uniprot id: A0A2Y9I4B0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

29088:STT3A
gene id: 29088:STT3A
uniprot id: A0A2Y9HKQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

29088:ARL6
gene id: 29088:ARL6
uniprot id: A0A8M1M7U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

29088:LOC110573273
gene id: 29088:LOC110573273
uniprot id: A0A8M1MUV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

29088:SEPTIN8
gene id: 29088:SEPTIN8
uniprot id: A0A2Y9I1H8
uniprot id: A0A2Y9I1Q8
uniprot id: A0A2Y9I1Z4
uniprot id: A0A2Y9I6D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Presynapse
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: synaptic vesicle membrane

29088:BACE2
gene id: 29088:BACE2
uniprot id: A0A2Y9G7B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Membrane

29088:LOC110576509
gene id: 29088:LOC110576509
uniprot id: A0A2Y9GPZ7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110576226
gene id: 29088:LOC110576226
uniprot id: A0A2Y9GT32
names: Similarity
messages: Belongs to the PRAME family.

29088:TMOD3
gene id: 29088:TMOD3
uniprot id: A0A8M1MJR7
names: Subcellular Location Annotation
messages: cytoskeleton

29088:ARHGEF18
gene id: 29088:ARHGEF18
uniprot id: A0A2Y9IAS3
uniprot id: A0A8M1MEL4
names: Subcellular Location Annotation
messages: Cytoplasm

29088:LOC110578445
gene id: 29088:LOC110578445
uniprot id: A0A8M1MQY9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

29088:LOC110582774
gene id: 29088:LOC110582774
uniprot id: A0A2Y9H9Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

29088:PTGIS
gene id: 29088:PTGIS
uniprot id: A0A2Y9GQM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

29088:LOC110581664
gene id: 29088:LOC110581664
uniprot id: A0A2Y9HDA2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SLC12A8
gene id: 29088:SLC12A8
uniprot id: A0A8M1MRG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

29088:MMP19
gene id: 29088:MMP19
uniprot id: A0A8M1MAC5
names: Similarity
messages: Belongs to the peptidase M10A family.

29088:LOC123324034
gene id: 29088:LOC123324034
uniprot id: A0A8M1MBT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:MEGF8
gene id: 29088:MEGF8
uniprot id: A0A8M1MXV7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:CMC2
gene id: 29088:CMC2
uniprot id: A0A2Y9I349
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

29088:LOC110590872
gene id: 29088:LOC110590872
uniprot id: A0A2Y9I0H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

29088:LOC110589764
gene id: 29088:LOC110589764
uniprot id: A0A8M1MGB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

29088:DGKE
gene id: 29088:DGKE
uniprot id: A0A2Y9I8F3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

29088:HPD
gene id: 29088:HPD
uniprot id: A0A2Y9HWL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

29088:LOC110573712
gene id: 29088:LOC110573712
uniprot id: A0A2Y9GKP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:PSPH
gene id: 29088:PSPH
uniprot id: A0A2Y9HWY5
uniprot id: A0A2Y9I3J1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

29088:WDR76
gene id: 29088:WDR76
uniprot id: A0A8M1MLS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Interacts with CUL4A and/or CUL4B.
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

29088:NCBP3
gene id: 29088:NCBP3
uniprot id: A0A2Y9IEJ3
names: Similarity
messages: Belongs to the NCBP3 family.

29088:FAM118B
gene id: 29088:FAM118B
uniprot id: A0A2Y9HKL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM118 family.
messages: Cajal body
messages: May play a role in Cajal bodies formation.

29088:PHB
gene id: 29088:PHB
uniprot id: A0A2Y9I8K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

29088:RBM10
gene id: 29088:RBM10
uniprot id: A0A8M1M1X9
uniprot id: A0A8M1M1Y4
uniprot id: A0A8M1M284
uniprot id: A0A8M1M290
uniprot id: A0A8M1M4G3
uniprot id: A0A8M1M601
uniprot id: A0A8M1M606
uniprot id: A0A8M1M9T6
uniprot id: A0A8M1M9U0
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110593807
gene id: 29088:LOC110593807
uniprot id: A0A2Y9IHH2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110574723
gene id: 29088:LOC110574723
uniprot id: A0A2Y9GJ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

29088:TMEM205
gene id: 29088:TMEM205
uniprot id: A0A2Y9IA22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM205 family.
messages: Membrane

29088:PFDN4
gene id: 29088:PFDN4
uniprot id: A0A2Y9G381
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

29088:PSMD12
gene id: 29088:PSMD12
uniprot id: A0A2Y9G4Z6
uniprot id: A0A8M1MVQ0
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

29088:LOC123323418
gene id: 29088:LOC123323418
uniprot id: A0A8M1M254
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

29088:ERBIN
gene id: 29088:ERBIN
uniprot id: A0A2Y9I140
uniprot id: A0A2Y9I1B1
uniprot id: A0A2Y9I1I2
uniprot id: A0A2Y9I7Y9
names: Similarity
messages: Belongs to the LAP (LRR and PDZ) protein family.

29088:SDHA
gene id: 29088:SDHA
uniprot id: A0A2Y9GU05
uniprot id: A0A2Y9GY93
uniprot id: A0A2Y9GZY2
uniprot id: A0A8M1MHK4
uniprot id: A0A8M1MP86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

29088:DBX1
gene id: 29088:DBX1
uniprot id: A0A2Y9GUJ0
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110572629
gene id: 29088:LOC110572629
uniprot id: A0A2Y9GCH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

29088:GPBP1
gene id: 29088:GPBP1
uniprot id: A0A2Y9I0M3
uniprot id: A0A2Y9I141
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

29088:SYN2
gene id: 29088:SYN2
uniprot id: A0A8M1MGU0
names: Similarity
messages: Belongs to the synapsin family.

29088:CPA1
gene id: 29088:CPA1
uniprot id: A0A2Y9HTU2
names: Similarity
messages: Belongs to the peptidase M14 family.

29088:NPEPPS
gene id: 29088:NPEPPS
uniprot id: A0A2Y9I910
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

29088:LONP2
gene id: 29088:LONP2
uniprot id: A0A2Y9IC45
uniprot id: A0A8M1MZF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta-oxidation through degradation of the self-processed forms of TYSND1.
messages: Belongs to the peptidase S16 family.
messages: Interacts with PEX5. Interacts with TYSND1.
messages: Peroxisome matrix

29088:TNFRSF1A
gene id: 29088:TNFRSF1A
uniprot id: A0A2Y9H3L6
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:CENPV
gene id: 29088:CENPV
uniprot id: A0A8M1MV51
names: Similarity
messages: Belongs to the Gfa family.

29088:EFNB2
gene id: 29088:EFNB2
uniprot id: A0A2Y9HQA2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:CLRN1
gene id: 29088:CLRN1
uniprot id: A0A2Y9GUW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

29088:ARHGAP32
gene id: 29088:ARHGAP32
uniprot id: A0A8M1MQZ9
uniprot id: A0A8M1MWV5
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

29088:NUDC
gene id: 29088:NUDC
uniprot id: A0A2Y9GJK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudC family.
messages: Midbody
messages: spindle

29088:PTPRS
gene id: 29088:PTPRS
uniprot id: A0A8M1MFG8
uniprot id: A0A8M1MFH8
uniprot id: A0A8M1MFJ7
uniprot id: A0A8M1MHJ3
uniprot id: A0A8M1MP49
uniprot id: A0A8M1MPC5
uniprot id: A0A8M1MPF3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

29088:ISCU
gene id: 29088:ISCU
uniprot id: A0A2Y9I590
uniprot id: A0A8M1MW42
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

29088:TNS4
gene id: 29088:TNS4
uniprot id: A0A2Y9IEU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

29088:LOC110578550
gene id: 29088:LOC110578550
uniprot id: A0A2Y9H3T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:NEUROD2
gene id: 29088:NEUROD2
uniprot id: A0A2Y9IFE4
names: Subcellular Location Annotation
messages: Nucleus

29088:TMEM145
gene id: 29088:TMEM145
uniprot id: A0A8M1MY55
uniprot id: A0A8M1MZI3
names: Subcellular Location Annotation
messages: Membrane

29088:LOXL4
gene id: 29088:LOXL4
uniprot id: A0A2Y9HZK6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

29088:LOC110580748
gene id: 29088:LOC110580748
uniprot id: A0A8M1MBB6
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

29088:LOC123324840
gene id: 29088:LOC123324840
uniprot id: A0A8M1MAK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:LLGL2
gene id: 29088:LLGL2
uniprot id: A0A2Y9GCA2
uniprot id: A0A8M1MUM9
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

29088:LOC110573247
gene id: 29088:LOC110573247
uniprot id: A0A2Y9GEA3
names: Similarity
messages: Belongs to the intermediate filament family.

29088:KCNK16
gene id: 29088:KCNK16
uniprot id: A0A2Y9GM83
uniprot id: A0A2Y9GME2
uniprot id: A0A2Y9GR26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

29088:SETD1B
gene id: 29088:SETD1B
uniprot id: A0A2Y9HRD0
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

29088:LOC110570839
gene id: 29088:LOC110570839
uniprot id: A0A2Y9G6B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:H1-5
gene id: 29088:H1-5
uniprot id: A0A2Y9GZV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

29088:ATG12
gene id: 29088:ATG12
uniprot id: A0A2Y9I1I7
uniprot id: A0A2Y9I205
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATG12 family.
messages: Forms a conjugate with ATG5.
messages: Ubiquitin-like protein involved in autophagic vesicle formation.

29088:CSPG4
gene id: 29088:CSPG4
uniprot id: A0A2Y9HIW6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:GALNT15
gene id: 29088:GALNT15
uniprot id: A0A2Y9G618
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:SERPINB3
gene id: 29088:SERPINB3
uniprot id: A0A2Y9GS13
names: Similarity
messages: Belongs to the serpin family.

29088:PURG
gene id: 29088:PURG
uniprot id: A0A2Y9HDS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

29088:LOC110593289
gene id: 29088:LOC110593289
uniprot id: A0A2Y9ICY8
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6c family.

29088:SCPEP1
gene id: 29088:SCPEP1
uniprot id: A0A2Y9IEF4
names: Similarity
messages: Belongs to the peptidase S10 family.

29088:ANK1
gene id: 29088:ANK1
uniprot id: A0A8M1M6X9
uniprot id: A0A8M1MCH3
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

29088:LOC110581150
gene id: 29088:LOC110581150
uniprot id: A0A2Y9H4M1
uniprot id: A0A2Y9HBB1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:GRB2
gene id: 29088:GRB2
uniprot id: A0A2Y9GF83
names: Subcellular Location Annotation
messages: Endosome
messages: Golgi apparatus
messages: Nucleus

29088:AGBL1
gene id: 29088:AGBL1
uniprot id: A0A2Y9GAX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

29088:GOT2
gene id: 29088:GOT2
uniprot id: A0A2Y9I871
uniprot id: A0A8M1M2P2
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

29088:LOC110588574
gene id: 29088:LOC110588574
uniprot id: A0A8M1M3U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

29088:MSTN
gene id: 29088:MSTN
uniprot id: A0A2Y9I4C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked. Interacts with WFIKKN2, leading to inhibit its activity. Interacts with FSTL3.
messages: Secreted

29088:DNAJB12
gene id: 29088:DNAJB12
uniprot id: A0A2Y9HZ43
uniprot id: A0A2Y9I0M8
names: Subcellular Location Annotation
messages: Membrane

29088:FABP2
gene id: 29088:FABP2
uniprot id: A0A2Y9GLZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cytoplasm
messages: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.

29088:PAIP2B
gene id: 29088:PAIP2B
uniprot id: A0A2Y9HZL1
names: Similarity
messages: Belongs to the PAIP2 family.

29088:YIPF2
gene id: 29088:YIPF2
uniprot id: A0A2Y9I9U5
uniprot id: A0A2Y9I9X0
uniprot id: A0A2Y9IEC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

29088:ZPBP2
gene id: 29088:ZPBP2
uniprot id: A0A8M1MV82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zona pellucida-binding protein Sp38 family.
messages: Secreted

29088:LOC110580854
gene id: 29088:LOC110580854
uniprot id: A0A2Y9HA79
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:GABRA3
gene id: 29088:GABRA3
uniprot id: A0A2Y9GJ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:MCHR1
gene id: 29088:MCHR1
uniprot id: A0A2Y9H017
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

29088:E2F6
gene id: 29088:E2F6
uniprot id: A0A2Y9HMZ7
uniprot id: A0A2Y9HTE9
uniprot id: A0A2Y9HUU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

29088:CHEK1
gene id: 29088:CHEK1
uniprot id: A0A2Y9HQX7
uniprot id: A0A2Y9HRR2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

29088:NR1H2
gene id: 29088:NR1H2
uniprot id: A0A2Y9GDG1
uniprot id: A0A2Y9GDI2
uniprot id: A0A2Y9GGE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

29088:CD47
gene id: 29088:CD47
uniprot id: A0A2Y9H8L9
uniprot id: A0A2Y9HED2
uniprot id: A0A8M1MR08
uniprot id: A0A8M1MXS6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:LOC110582827
gene id: 29088:LOC110582827
uniprot id: A0A2Y9HFT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

29088:KIF9
gene id: 29088:KIF9
uniprot id: A0A8M1MUZ5
uniprot id: A0A8M1MV01
uniprot id: A0A8M1MWQ6
uniprot id: A0A8M1MZ84
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:CA4
gene id: 29088:CA4
uniprot id: A0A2Y9IEI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Cell membrane
messages: Interacts with SLC4A4.
messages: Membrane
messages: Reversible hydration of carbon dioxide.

29088:MFSD14A
gene id: 29088:MFSD14A
uniprot id: A0A2Y9H222
uniprot id: A0A2Y9H245
uniprot id: A0A2Y9H259
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

29088:LOC110576616
gene id: 29088:LOC110576616
uniprot id: A0A2Y9GW63
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

29088:TRUB1
gene id: 29088:TRUB1
uniprot id: A0A2Y9I1V8
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

29088:GATC
gene id: 29088:GATC
uniprot id: A0A2Y9I9Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

29088:TRMU
gene id: 29088:TRMU
uniprot id: A0A2Y9GWA9
uniprot id: A0A8M1MCW9
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

29088:TGFA
gene id: 29088:TGFA
uniprot id: A0A2Y9HT73
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC123323164
gene id: 29088:LOC123323164
uniprot id: A0A8M1M353
uniprot id: A0A8M1M629
uniprot id: A0A8M1M6D2
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

29088:GDPD1
gene id: 29088:GDPD1
uniprot id: A0A2Y9IEV1
uniprot id: A0A8M1MWH4
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

29088:AQP4
gene id: 29088:AQP4
uniprot id: A0A2Y9GRT2
uniprot id: A0A2Y9GVR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

29088:PDHB
gene id: 29088:PDHB
uniprot id: A0A2Y9HMP6
uniprot id: A0A8M1MFT6
uniprot id: A0A8M1MHW8
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

29088:FAM76A
gene id: 29088:FAM76A
uniprot id: A0A2Y9GJL3
uniprot id: A0A8M1M7U6
uniprot id: A0A8M1MBE1
names: Similarity
messages: Belongs to the FAM76 family.

29088:LOC110582581
gene id: 29088:LOC110582581
uniprot id: A0A2Y9H9H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

29088:APOA2
gene id: 29088:APOA2
uniprot id: A0A7F3R6R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein A2 family.
messages: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.
messages: Monomer. Interacts with NAXE and NDRG1.
messages: Secreted

29088:PSMD2
gene id: 29088:PSMD2
uniprot id: A0A2Y9H9S1
uniprot id: A0A8M1MS14
uniprot id: A0A8M1MS25
uniprot id: A0A8M1MY86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S2 family.
messages: Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

29088:TASOR
gene id: 29088:TASOR
uniprot id: A0A2Y9HG60
uniprot id: A0A2Y9HGL2
uniprot id: A0A2Y9HMI4
uniprot id: A0A2Y9HMQ6
uniprot id: A0A8M1MU20
uniprot id: A0A8M1MVU7
uniprot id: A0A8M1MWZ6
names: Similarity
messages: Belongs to the TASOR family.

29088:MICAL2
gene id: 29088:MICAL2
uniprot id: A0A8M1MRI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

29088:KIAA1191
gene id: 29088:KIAA1191
uniprot id: A0A2Y9HWE3
uniprot id: A0A2Y9HXZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P33MONOX family.
messages: Cytoplasm
messages: Interacts with NELFB, NOL12 and PRNP.
messages: Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth.

29088:RBX1
gene id: 29088:RBX1
uniprot id: A0A2Y9H0Z5
names: Similarity
messages: Belongs to the RING-box family.

29088:LOC110578806
gene id: 29088:LOC110578806
uniprot id: A0A2Y9GXI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

29088:NCAM1
gene id: 29088:NCAM1
uniprot id: A0A2Y9HKH7
uniprot id: A0A2Y9HKS0
uniprot id: A0A2Y9HRA2
uniprot id: A0A2Y9HS76
names: Function
messages: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.

29088:PLOD3
gene id: 29088:PLOD3
uniprot id: A0A2Y9I1D8
uniprot id: A0A8M1MJN1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

29088:LOC110578388
gene id: 29088:LOC110578388
uniprot id: A0A2Y9GWL1
names: Similarity
messages: Belongs to the MIF family.

29088:KCNJ15
gene id: 29088:KCNJ15
uniprot id: A0A2Y9G7Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

29088:RIPPLY1
gene id: 29088:RIPPLY1
uniprot id: A0A2Y9G5D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

29088:LOC110574607
gene id: 29088:LOC110574607
uniprot id: A0A8M1MB74
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.
messages: Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.

29088:LOC110594019
gene id: 29088:LOC110594019
uniprot id: A0A8M1MT56
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

29088:LOC110584476
gene id: 29088:LOC110584476
uniprot id: A0A8M1MXL7
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:PSMA5
gene id: 29088:PSMA5
uniprot id: A0A2Y9H709
uniprot id: A0A2Y9H8N1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

29088:TSEN2
gene id: 29088:TSEN2
uniprot id: A0A2Y9HG19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

29088:SLC22A2
gene id: 29088:SLC22A2
uniprot id: A0A2Y9HBS6
uniprot id: A0A2Y9HC00
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

29088:LOC110583457
gene id: 29088:LOC110583457
uniprot id: A0A2Y9HBW6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:ADAMTS10
gene id: 29088:ADAMTS10
uniprot id: A0A8M1MK69
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:ZDHHC4
gene id: 29088:ZDHHC4
uniprot id: A0A2Y9GDQ3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

29088:SIAH3
gene id: 29088:SIAH3
uniprot id: A0A2Y9HPF0
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

29088:LAPTM4B
gene id: 29088:LAPTM4B
uniprot id: A0A2Y9H492
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAPTM4/LAPTM5 transporter family.
messages: Cell membrane
messages: Cell projection
messages: Endomembrane system
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: multivesicular body lumen
messages: multivesicular body membrane

29088:GFOD2
gene id: 29088:GFOD2
uniprot id: A0A2Y9I5Y6
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

29088:SLC31A2
gene id: 29088:SLC31A2
uniprot id: A0A2Y9H6A1
uniprot id: A0A2Y9HCZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

29088:OSBPL11
gene id: 29088:OSBPL11
uniprot id: A0A2Y9H8G6
names: Similarity
messages: Belongs to the OSBP family.

29088:NDUFA6
gene id: 29088:NDUFA6
uniprot id: A0A2Y9GW17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:FZD4
gene id: 29088:FZD4
uniprot id: A0A2Y9GSD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

29088:LOC110575420
gene id: 29088:LOC110575420
uniprot id: A0A8M1MFM5
names: Similarity
messages: Belongs to the TGF-beta family.

29088:SLC24A3
gene id: 29088:SLC24A3
uniprot id: A0A2Y9HXV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

29088:LOC110586430
gene id: 29088:LOC110586430
uniprot id: A0A2Y9HKP0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TNK2
gene id: 29088:TNK2
uniprot id: A0A2Y9H9G5
uniprot id: A0A2Y9H9G8
uniprot id: A0A2Y9HFD8
uniprot id: A0A2Y9HG82
uniprot id: A0A8M1MPE1
uniprot id: A0A8M1MPF2
uniprot id: A0A8M1MPG7
uniprot id: A0A8M1MSN7
uniprot id: A0A8M1MSQ2
uniprot id: A0A8M1MXX5
uniprot id: A0A8M1MXY0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nucleus

29088:LOC110588014
gene id: 29088:LOC110588014
uniprot id: A0A2Y9HQQ0
uniprot id: A0A2Y9HQT7
uniprot id: A0A2Y9HX59
uniprot id: A0A8M1MEN2
names: Subcellular Location Annotation
messages: Cytoplasm

29088:PIK3CA
gene id: 29088:PIK3CA
uniprot id: A0A2Y9H8I3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

29088:LOC110593574
gene id: 29088:LOC110593574
uniprot id: A0A2Y9IGK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110580820
gene id: 29088:LOC110580820
uniprot id: A0A2Y9HA32
names: Similarity
messages: Belongs to the methyltransferase superfamily. HEN1 family.

29088:FGB
gene id: 29088:FGB
uniprot id: A0A2Y9HSU9
uniprot id: A0A8M1M4V0
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

29088:LOC110578127
gene id: 29088:LOC110578127
uniprot id: A0A2Y9H1M1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

29088:MFAP1
gene id: 29088:MFAP1
uniprot id: A0A2Y9HN58
names: Function
names: Similarity
messages: Belongs to the MFAP1 family.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.

29088:LOC110576477
gene id: 29088:LOC110576477
uniprot id: A0A2Y9GQ83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:C11H11orf54
gene id: 29088:C11H11orf54
uniprot id: A0A2Y9G9B6
uniprot id: A0A2Y9GAF0
uniprot id: A0A8M1MQ52
uniprot id: A0A8M1MX77
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

29088:MARVELD2
gene id: 29088:MARVELD2
uniprot id: A0A2Y9I3A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

29088:GRK1
gene id: 29088:GRK1
uniprot id: A0A2Y9HJ22
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

29088:OLFM4
gene id: 29088:OLFM4
uniprot id: A0A2Y9HPI1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:RMND1
gene id: 29088:RMND1
uniprot id: A0A2Y9HI41
names: Similarity
messages: Belongs to the RMD1/sif2 family.

29088:LOC110594029
gene id: 29088:LOC110594029
uniprot id: A0A8M1MJI0
uniprot id: A0A8M1MTJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: nucleolus

29088:B3GNT5
gene id: 29088:B3GNT5
uniprot id: A0A2Y9HFH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:MEGF11
gene id: 29088:MEGF11
uniprot id: A0A2Y9HJ91
uniprot id: A0A8M1ML83
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:PLEKHA8
gene id: 29088:PLEKHA8
uniprot id: A0A2Y9H602
uniprot id: A0A8M1MQ14
names: Subcellular Location Annotation
messages: Membrane
messages: trans-Golgi network membrane

29088:PLPP5
gene id: 29088:PLPP5
uniprot id: A0A2Y9GDN6
uniprot id: A0A8M1M4U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

29088:CYLD
gene id: 29088:CYLD
uniprot id: A0A2Y9IJH0
uniprot id: A0A8M1MW68
uniprot id: A0A8M1MXG2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: centrosome
messages: cilium basal body
messages: perinuclear region
messages: spindle

29088:LOC110583520
gene id: 29088:LOC110583520
uniprot id: A0A2Y9HBV4
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

29088:MRPL44
gene id: 29088:MRPL44
uniprot id: A0A2Y9GKX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.
messages: Mitochondrion

29088:NETO1
gene id: 29088:NETO1
uniprot id: A0A8M1MV24
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:CFAP97
gene id: 29088:CFAP97
uniprot id: A0A2Y9HDX7
uniprot id: A0A8M1M952
names: Similarity
messages: Belongs to the CFAP97 family.

29088:LOC110591389
gene id: 29088:LOC110591389
uniprot id: A0A8M1MDC2
names: Function
names: Subcellular Location Annotation
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

29088:RARB
gene id: 29088:RARB
uniprot id: A0A2Y9G6E4
uniprot id: A0A2Y9G6E7
uniprot id: A0A2Y9G8V5
uniprot id: A0A2Y9G9Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

29088:SLC26A4
gene id: 29088:SLC26A4
uniprot id: A0A2Y9GKT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Cell membrane
messages: Membrane
messages: Sodium-independent transporter of chloride and iodide.

29088:UNC119
gene id: 29088:UNC119
uniprot id: A0A2Y9I7K5
uniprot id: A0A8M1MXC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDE6D/unc-119 family.
messages: spindle

29088:MARK2
gene id: 29088:MARK2
uniprot id: A0A2Y9GPG7
uniprot id: A0A2Y9GPH2
uniprot id: A0A2Y9GPP3
uniprot id: A0A2Y9GPT7
uniprot id: A0A2Y9GPU2
uniprot id: A0A2Y9GTJ2
uniprot id: A0A2Y9GTJ8
uniprot id: A0A2Y9GV97
uniprot id: A0A2Y9GVA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

29088:GDF7
gene id: 29088:GDF7
uniprot id: A0A2Y9HVH5
names: Similarity
messages: Belongs to the TGF-beta family.

29088:TMEM256
gene id: 29088:TMEM256
uniprot id: A0A2Y9HFQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM256 family.
messages: Membrane

29088:PLXNA1
gene id: 29088:PLXNA1
uniprot id: A0A2Y9HG37
uniprot id: A0A8M1MSI4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:LOC123324831
gene id: 29088:LOC123324831
uniprot id: A0A8M1M9Y4
names: Similarity
messages: Belongs to the GAGE family.

29088:EEF1G
gene id: 29088:EEF1G
uniprot id: A0A2Y9GPM2
names: Function
names: Subunit
messages: EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
messages: Probably plays a role in anchoring the complex to other cellular components.

29088:UBN1
gene id: 29088:UBN1
uniprot id: A0A2Y9HQB0
uniprot id: A0A2Y9HV82
uniprot id: A0A2Y9HWR9
names: Similarity
messages: Belongs to the ubinuclein family.

29088:LOC110581754
gene id: 29088:LOC110581754
uniprot id: A0A2Y9HC68
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

29088:IDS
gene id: 29088:IDS
uniprot id: A0A2Y9GG97
uniprot id: A0A8M1M181
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

29088:LOC110573775
gene id: 29088:LOC110573775
uniprot id: A0A8M1MZD7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

29088:PNN
gene id: 29088:PNN
uniprot id: A0A2Y9I438
uniprot id: A0A8M1MMC7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pinin family.
messages: Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.
messages: Nucleus speckle
messages: desmosome

29088:IFNK
gene id: 29088:IFNK
uniprot id: A0A2Y9GFB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

29088:PYGB
gene id: 29088:PYGB
uniprot id: A0A2Y9HXE2
uniprot id: A0A2Y9HXP1
uniprot id: A0A8M1MPI3
uniprot id: A0A8M1MQU2
uniprot id: A0A8M1MWR2
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

29088:LOC110576428
gene id: 29088:LOC110576428
uniprot id: A0A2Y9GTW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MGRN1
gene id: 29088:MGRN1
uniprot id: A0A2Y9HQ31
uniprot id: A0A2Y9HQI5
uniprot id: A0A8M1MG29
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

29088:FGFR2
gene id: 29088:FGFR2
uniprot id: A0A2Y9I675
uniprot id: A0A2Y9I725
uniprot id: A0A2Y9IB08
uniprot id: A0A2Y9IB12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

29088:ANO3
gene id: 29088:ANO3
uniprot id: A0A2Y9GUL0
uniprot id: A0A2Y9GWA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

29088:PABPN1
gene id: 29088:PABPN1
uniprot id: A0A2Y9HHK6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:CALHM6
gene id: 29088:CALHM6
uniprot id: A0A2Y9HCD3
uniprot id: A0A8M1MS19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

29088:LOC110571488
gene id: 29088:LOC110571488
uniprot id: A0A8M1MIZ2
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

29088:LOC123323183
gene id: 29088:LOC123323183
uniprot id: A0A2Y9HLC3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:LOC110573136
gene id: 29088:LOC110573136
uniprot id: A0A8M1M6N3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:OCRL
gene id: 29088:OCRL
uniprot id: A0A8M1M4J4
uniprot id: A0A8M1M9W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

29088:TMEM129
gene id: 29088:TMEM129
uniprot id: A0A2Y9G2S1
uniprot id: A0A2Y9G379
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM129 family.
messages: Membrane

29088:SBK2
gene id: 29088:SBK2
uniprot id: A0A2Y9GJ56
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:LOC110588807
gene id: 29088:LOC110588807
uniprot id: A0A2Y9HYC8
uniprot id: A0A2Y9HZX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Nucleus

29088:SLC1A1
gene id: 29088:SLC1A1
uniprot id: A0A2Y9HKB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

29088:LOC123325700
gene id: 29088:LOC123325700
uniprot id: A0A8M1MTH2
names: Similarity
messages: Belongs to the serpin family.

29088:SPOCK1
gene id: 29088:SPOCK1
uniprot id: A0A2Y9I7T9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:CPZ
gene id: 29088:CPZ
uniprot id: A0A2Y9G5A9
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LYPLA1
gene id: 29088:LYPLA1
uniprot id: A0A2Y9GXA2
uniprot id: A0A8M1M8N2
uniprot id: A0A8M1MAT8
uniprot id: A0A8M1MC66
uniprot id: A0A8M1MGS7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

29088:LAP3
gene id: 29088:LAP3
uniprot id: A0A2Y9GAB5
uniprot id: A0A8M1M4K8
names: Similarity
names: Subunit
messages: Belongs to the peptidase M17 family.
messages: Homohexamer.

29088:CCNA1
gene id: 29088:CCNA1
uniprot id: A0A2Y9G4M3
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

29088:HDAC9
gene id: 29088:HDAC9
uniprot id: A0A2Y9H1G9
uniprot id: A0A2Y9H1H2
uniprot id: A0A2Y9H1K2
uniprot id: A0A2Y9H1K5
uniprot id: A0A2Y9H1L4
uniprot id: A0A2Y9H1L8
uniprot id: A0A2Y9H6A3
uniprot id: A0A2Y9H809
uniprot id: A0A2Y9H813
uniprot id: A0A8M1MQB0
uniprot id: A0A8M1MS74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus

29088:PHACTR3
gene id: 29088:PHACTR3
uniprot id: A0A2Y9G5S2
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

29088:B3GNT4
gene id: 29088:B3GNT4
uniprot id: A0A2Y9HR70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:PTK2B
gene id: 29088:PTK2B
uniprot id: A0A2Y9HS68
uniprot id: A0A2Y9HXJ4
uniprot id: A0A2Y9HZ33
names: Subcellular Location Annotation
messages: Cell membrane
messages: cell cortex
messages: focal adhesion

29088:QPCT
gene id: 29088:QPCT
uniprot id: A0A2Y9HNZ1
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

29088:PDS5B
gene id: 29088:PDS5B
uniprot id: A0A2Y9G726
names: Similarity
messages: Belongs to the PDS5 family.

29088:NCOR2
gene id: 29088:NCOR2
uniprot id: A0A2Y9HR84
uniprot id: A0A2Y9HRM5
uniprot id: A0A2Y9HRN2
uniprot id: A0A2Y9HRN5
uniprot id: A0A2Y9HRP2
uniprot id: A0A2Y9HWH6
uniprot id: A0A2Y9HY55
uniprot id: A0A2Y9HY59
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

29088:RPL9
gene id: 29088:RPL9
uniprot id: A0A2Y9I6N1
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

29088:WRN
gene id: 29088:WRN
uniprot id: A0A2Y9HJP4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

29088:TNRC6B
gene id: 29088:TNRC6B
uniprot id: A0A8M1MK60
names: Similarity
messages: Belongs to the GW182 family.

29088:LOC110593846
gene id: 29088:LOC110593846
uniprot id: A0A8M1MXA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

29088:FOXI2
gene id: 29088:FOXI2
uniprot id: A0A2Y9IDS9
names: Subcellular Location Annotation
messages: Nucleus

29088:ITPKB
gene id: 29088:ITPKB
uniprot id: A0A2Y9G813
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

29088:RPL36AL
gene id: 29088:RPL36AL
uniprot id: A0A2Y9I4I3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

29088:TRIT1
gene id: 29088:TRIT1
uniprot id: A0A2Y9GL03
uniprot id: A0A2Y9GLB1
names: Function
names: Similarity
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.

29088:LOC110593914
gene id: 29088:LOC110593914
uniprot id: A0A2Y9IHZ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:GCDH
gene id: 29088:GCDH
uniprot id: A0A2Y9I9M5
uniprot id: A0A2Y9IAA2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

29088:ALDH18A1
gene id: 29088:ALDH18A1
uniprot id: A0A2Y9HTQ5
uniprot id: A0A8M1MF67
names: Similarity
messages: In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
messages: In the N-terminal section; belongs to the glutamate 5-kinase family.

29088:RSPH3
gene id: 29088:RSPH3
uniprot id: A0A2Y9HHM2
names: Similarity
messages: Belongs to the flagellar radial spoke RSP3 family.

29088:POU4F1
gene id: 29088:POU4F1
uniprot id: A0A8M1M6K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

29088:B3GNT2
gene id: 29088:B3GNT2
uniprot id: A0A2Y9HT74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:TMEM41A
gene id: 29088:TMEM41A
uniprot id: A0A2Y9H8M4
uniprot id: A0A8M1MQ23
uniprot id: A0A8M1MTA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

29088:SLC6A4
gene id: 29088:SLC6A4
uniprot id: A0A8M1MXM6
names: Subcellular Location Annotation
messages: Membrane

29088:ISM1
gene id: 29088:ISM1
uniprot id: A0A2Y9I465
names: Similarity
messages: Belongs to the isthmin family.

29088:SOX12
gene id: 29088:SOX12
uniprot id: A0A2Y9GZK8
names: Subcellular Location Annotation
messages: Nucleus

29088:CAT
gene id: 29088:CAT
uniprot id: A0A2Y9GUU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Peroxisome

29088:HAT1
gene id: 29088:HAT1
uniprot id: A0A2Y9IAT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.
messages: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).

29088:RPL21
gene id: 29088:RPL21
uniprot id: A0A2Y9G782
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

29088:ABL1
gene id: 29088:ABL1
uniprot id: A0A2Y9H5N5
uniprot id: A0A2Y9H5R0
uniprot id: A0A8M1MRG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

29088:SLC7A7
gene id: 29088:SLC7A7
uniprot id: A0A2Y9HH85
uniprot id: A0A8M1MIX3
names: Subcellular Location Annotation
messages: Membrane

29088:IDI1
gene id: 29088:IDI1
uniprot id: A0A2Y9H4J9
uniprot id: A0A8M1MJA2
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

29088:SNTG2
gene id: 29088:SNTG2
uniprot id: A0A8M1MLR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

29088:PDK1
gene id: 29088:PDK1
uniprot id: A0A2Y9I3S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

29088:COQ7
gene id: 29088:COQ7
uniprot id: A0A2Y9HQP4
uniprot id: A0A8M1MB48
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion inner membrane

29088:LOC110588948
gene id: 29088:LOC110588948
uniprot id: A0A2Y9HTX3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

29088:DXO
gene id: 29088:DXO
uniprot id: A0A2Y9HS29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Binds 2 magnesium ions.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

29088:SS18L1
gene id: 29088:SS18L1
uniprot id: A0A2Y9G6X2
names: Similarity
messages: Belongs to the SS18 family.

29088:ILDR2
gene id: 29088:ILDR2
uniprot id: A0A8M1MMV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

29088:OAT
gene id: 29088:OAT
uniprot id: A0A2Y9I6F9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

29088:AMZ1
gene id: 29088:AMZ1
uniprot id: A0A2Y9GCL0
uniprot id: A0A8M1MDI0
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

29088:RNF170
gene id: 29088:RNF170
uniprot id: A0A2Y9GID5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:DEFB121
gene id: 29088:DEFB121
uniprot id: A0A2Y9H4V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

29088:ADRA1A
gene id: 29088:ADRA1A
uniprot id: A0A2Y9HYX5
uniprot id: A0A8M1M666
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane
messages: caveola

29088:DPM2
gene id: 29088:DPM2
uniprot id: A0A2Y9HBT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

29088:CAPRIN1
gene id: 29088:CAPRIN1
uniprot id: A0A2Y9GT54
uniprot id: A0A8M1MRH7
names: Similarity
messages: Belongs to the caprin family.

29088:SEC11A
gene id: 29088:SEC11A
uniprot id: A0A2Y9GB88
uniprot id: A0A2Y9GFE5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:SLC2A10
gene id: 29088:SLC2A10
uniprot id: A0A2Y9H681
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

29088:LOC110581674
gene id: 29088:LOC110581674
uniprot id: A0A2Y9HDB1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:BRK1
gene id: 29088:BRK1
uniprot id: A0A2Y9HGF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRK1 family.
messages: cytoskeleton

29088:NIPSNAP3A
gene id: 29088:NIPSNAP3A
uniprot id: A0A2Y9H5F7
uniprot id: A0A8M1MYG1
names: Similarity
messages: Belongs to the NipSnap family.

29088:FITM1
gene id: 29088:FITM1
uniprot id: A0A2Y9HHV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. FIT1 subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays an important role in the formation of lipid droplets (LDs), which are storage organelles at the center of lipid and energy homeostasis. Directly binds to diacylglycerol (DAGs) and triacylglycerol.

29088:SERPINH1
gene id: 29088:SERPINH1
uniprot id: A0A2Y9I8H4
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

29088:SF3B6
gene id: 29088:SF3B6
uniprot id: A0A2Y9HP98
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110580715
gene id: 29088:LOC110580715
uniprot id: A0A2Y9H348
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:RPL22
gene id: 29088:RPL22
uniprot id: A0A2Y9GP08
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

29088:CACNA2D4
gene id: 29088:CACNA2D4
uniprot id: A0A2Y9H389
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

29088:ODF2
gene id: 29088:ODF2
uniprot id: A0A2Y9HD60
uniprot id: A0A8M1MRK3
uniprot id: A0A8M1MRK6
uniprot id: A0A8M1MRL1
uniprot id: A0A8M1MTF6
uniprot id: A0A8M1MTG0
uniprot id: A0A8M1MUT3
uniprot id: A0A8M1MUT8
uniprot id: A0A8M1MYJ2
uniprot id: A0A8M1MYJ3
uniprot id: A0A8M1MYJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

29088:NDUFAF1
gene id: 29088:NDUFAF1
uniprot id: A0A2Y9HI15
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

29088:KCNA6
gene id: 29088:KCNA6
uniprot id: A0A2Y9H964
names: Subcellular Location Annotation
messages: Membrane

29088:PAQR9
gene id: 29088:PAQR9
uniprot id: A0A2Y9G8A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

29088:LOC110572958
gene id: 29088:LOC110572958
uniprot id: A0A2Y9GDG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3. May form a heterodimer with CTU2/NCS2.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

29088:TBX15
gene id: 29088:TBX15
uniprot id: A0A2Y9H8Z9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

29088:LOC110576676
gene id: 29088:LOC110576676
uniprot id: A0A8M1MXM1
names: Similarity
messages: Belongs to the cyclin family.

29088:SEPTIN5
gene id: 29088:SEPTIN5
uniprot id: A0A2Y9H4J4
uniprot id: A0A2Y9H4K7
uniprot id: A0A2Y9H4L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: cytoskeleton

29088:SLC2A2
gene id: 29088:SLC2A2
uniprot id: A0A2Y9I2S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Membrane

29088:COG4
gene id: 29088:COG4
uniprot id: A0A2Y9I4T1
uniprot id: A0A8M1M024
uniprot id: A0A8M1M0C8
uniprot id: A0A8M1M2M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG4 family.
messages: Golgi apparatus membrane

29088:TRUB2
gene id: 29088:TRUB2
uniprot id: A0A2Y9H5T1
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

29088:PSMD3
gene id: 29088:PSMD3
uniprot id: A0A2Y9ICJ7
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

29088:LOC110578348
gene id: 29088:LOC110578348
uniprot id: A0A2Y9GWH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

29088:LOC110574785
gene id: 29088:LOC110574785
uniprot id: A0A8M1MFW5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

29088:LOC110576481
gene id: 29088:LOC110576481
uniprot id: A0A2Y9GQ50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:GALC
gene id: 29088:GALC
uniprot id: A0A2Y9GB13
uniprot id: A0A2Y9GC01
uniprot id: A0A8M1MUN0
names: Similarity
messages: Belongs to the glycosyl hydrolase 59 family.

29088:ARAP2
gene id: 29088:ARAP2
uniprot id: A0A8M1M509
names: Subcellular Location Annotation
messages: Cytoplasm

29088:CBLB
gene id: 29088:CBLB
uniprot id: A0A2Y9H8G1
uniprot id: A0A2Y9H8N6
uniprot id: A0A2Y9HE70
uniprot id: A0A2Y9HF88
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

29088:B4GALNT3
gene id: 29088:B4GALNT3
uniprot id: A0A2Y9H8V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

29088:CXCL8
gene id: 29088:CXCL8
uniprot id: A0A2Y9I6R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Chemotactic factor that mediates inflammatory response by attracting neutrophils, basophils, and T-cells to clear pathogens and protect the host from infection. Also plays an important role in neutrophil activation. Released in response to an inflammatory stimulus, exerts its effect by binding to the G-protein-coupled receptors CXCR1 and CXCR2, primarily found in neutrophils, monocytes and endothelial cells. G-protein heterotrimer (alpha, beta, gamma subunits) constitutively binds to CXCR1/CXCR2 receptor and activation by IL8 leads to beta and gamma subunits release from Galpha (GNAI2 in neutrophils) and activation of several downstream signaling pathways including PI3K and MAPK pathways.
messages: Homodimer.
messages: Secreted

29088:TMEM123
gene id: 29088:TMEM123
uniprot id: A0A2Y9HQP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

29088:LOC110592778
gene id: 29088:LOC110592778
uniprot id: A0A2Y9I6R6
uniprot id: A0A8M1ME22
uniprot id: A0A8M1ME66
uniprot id: A0A8M1MG78
uniprot id: A0A8M1MG85
uniprot id: A0A8M1MHM3
uniprot id: A0A8M1MMS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

29088:YIF1A
gene id: 29088:YIF1A
uniprot id: A0A2Y9GNB0
uniprot id: A0A8M1MMR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:TNFRSF21
gene id: 29088:TNFRSF21
uniprot id: A0A2Y9HEK4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110577980
gene id: 29088:LOC110577980
uniprot id: A0A2Y9H169
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCO1/2 family.
messages: Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.
messages: Homodimer.
messages: Mitochondrion inner membrane

29088:PIGZ
gene id: 29088:PIGZ
uniprot id: A0A2Y9HG44
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:LOC110587414
gene id: 29088:LOC110587414
uniprot id: A0A2Y9HNS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

29088:CCDC65
gene id: 29088:CCDC65
uniprot id: A0A2Y9IDW1
names: Subcellular Location Annotation
names: Subunit
messages: Component of the nexin-dynein regulatory complex (N-DRC).
messages: flagellum axoneme

29088:ITGA2B
gene id: 29088:ITGA2B
uniprot id: A0A8M1MVC0
uniprot id: A0A8M1MXQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

29088:CEP162
gene id: 29088:CEP162
uniprot id: A0A2Y9HB98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP162 family.
messages: centriole

29088:BCAP31
gene id: 29088:BCAP31
uniprot id: A0A8M1M172
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a role in the export of secreted proteins in the ER.

29088:CDH7
gene id: 29088:CDH7
uniprot id: A0A2Y9GS56
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

29088:PIGK
gene id: 29088:PIGK
uniprot id: A0A2Y9G7R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C13 family.
messages: Endoplasmic reticulum membrane
messages: Forms a complex with PIGT, PIGS, PIGU and GAA1.
messages: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

29088:BCL2L10
gene id: 29088:BCL2L10
uniprot id: A0A2Y9HCH0
names: Similarity
messages: Belongs to the Bcl-2 family.

29088:LOC110581034
gene id: 29088:LOC110581034
uniprot id: A0A8M1MAE3
names: Similarity
messages: Belongs to the GroES chaperonin family.

29088:GPI
gene id: 29088:GPI
uniprot id: A0A2Y9I5E9
uniprot id: A0A8M1M0R8
uniprot id: A0A8M1M4K2
names: Similarity
messages: Belongs to the GPI family.

29088:LOC110591870
gene id: 29088:LOC110591870
uniprot id: A0A2Y9IAM9
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

29088:FMNL2
gene id: 29088:FMNL2
uniprot id: A0A2Y9I5P8
uniprot id: A0A8M1M5T0
uniprot id: A0A8M1M879
uniprot id: A0A8M1M9N3
names: Similarity
messages: Belongs to the formin homology family.

29088:DOP1A
gene id: 29088:DOP1A
uniprot id: A0A8M1MI85
uniprot id: A0A8M1MI86
uniprot id: A0A8M1MKA6
uniprot id: A0A8M1MLM0
uniprot id: A0A8M1MS76
names: Similarity
messages: Belongs to the dopey family.

29088:HOXB5
gene id: 29088:HOXB5
uniprot id: A0A2Y9I6Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

29088:LOC110572233
gene id: 29088:LOC110572233
uniprot id: A0A2Y9GAW0
uniprot id: A0A2Y9GB10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
messages: Component of the NuA4 histone acetyltransferase complex. Component of the hbo1 complex. Component of the moz/morf complex.
messages: kinetochore
messages: nucleolus

29088:LOC110590583
gene id: 29088:LOC110590583
uniprot id: A0A8M1MLL5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Interacts with PPIF; the interaction is impaired by CsA.
messages: Membrane
messages: Mitochondrion inner membrane

29088:TBX19
gene id: 29088:TBX19
uniprot id: A0A2Y9GGN9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

29088:DNASE2
gene id: 29088:DNASE2
uniprot id: A0A2Y9IBG2
names: Similarity
messages: Belongs to the DNase II family.

29088:TRIM32
gene id: 29088:TRIM32
uniprot id: A0A2Y9H6X4
names: Similarity
messages: Belongs to the TRIM/RBCC family.

29088:DEGS1
gene id: 29088:DEGS1
uniprot id: A0A2Y9G883
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Interacts with RLBP1; the interaction increases synthesis of chromophore-precursors by DEGS1.
messages: Membrane

29088:MIGA1
gene id: 29088:MIGA1
uniprot id: A0A8M1M7Z9
names: Similarity
messages: Belongs to the mitoguardin family.

29088:SIRT4
gene id: 29088:SIRT4
uniprot id: A0A2Y9I5G7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: According to some authors, ADP-ribosyltransferase activity of sirtuins may be an inefficient side reaction of the deacetylase activity and may not be physiologically relevant.
messages: Acts as NAD-dependent protein lipoamidase, biotinylase, deacetylase and ADP-ribosyl transferase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitochondrial glutamine metabolism by mediating mono ADP-ribosylation of GLUD1: expressed in response to DNA damage and negatively regulates anaplerosis by inhibiting GLUD1, leading to block metabolism of glutamine into tricarboxylic acid cycle and promoting cell cycle arrest. In response to mTORC1 signal, SIRT4 expression is repressed, promoting anaplerosis and cell proliferation. Acts as a tumor suppressor. Also acts as a NAD-dependent protein deacetylase: mediates deacetylation of 'Lys-471' of MLYCD, inhibiting its activity, thereby acting as a regulator of lipid homeostasis. Does not seem to deacetylate PC. Controls fatty acid oxidation by inhibiting PPARA transcriptional activation. Impairs SIRT1-PPARA interaction probably through the regulation of NAD(+) levels. Down-regulates insulin secretion.
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Interacts with GLUD1, IDE and SLC25A5. Interacts with DLAT and PDHX.
messages: Mitochondrion matrix

29088:TALDO1
gene id: 29088:TALDO1
uniprot id: A0A2Y9HEZ7
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

29088:PRKAR1B
gene id: 29088:PRKAR1B
uniprot id: A0A2Y9GA06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

29088:LOC110589977
gene id: 29088:LOC110589977
uniprot id: A0A8M1MLV9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

29088:PWP2
gene id: 29088:PWP2
uniprot id: A0A2Y9G9U7
uniprot id: A0A2Y9GAV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

29088:GYS2
gene id: 29088:GYS2
uniprot id: A0A2Y9H3V2
uniprot id: A0A2Y9HAI9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

29088:IRX4
gene id: 29088:IRX4
uniprot id: A0A2Y9GU48
uniprot id: A0A2Y9GY82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

29088:AP1M2
gene id: 29088:AP1M2
uniprot id: A0A2Y9I9Y3
uniprot id: A0A2Y9IAL5
uniprot id: A0A8M1MTB2
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

29088:FAM229B
gene id: 29088:FAM229B
uniprot id: A0A2Y9HC58
names: Similarity
messages: Belongs to the FAM229 family.

29088:C13H9orf78
gene id: 29088:C13H9orf78
uniprot id: A0A2Y9H5V2
uniprot id: A0A2Y9HBA9
uniprot id: A0A2Y9HCM9
names: Similarity
messages: Belongs to the TLS1 family.

29088:CRTC2
gene id: 29088:CRTC2
uniprot id: A0A2Y9GF50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

29088:PPCS
gene id: 29088:PPCS
uniprot id: A0A2Y9GJW7
uniprot id: A0A2Y9GK36
uniprot id: A0A2Y9GNF7
names: Similarity
messages: Belongs to the PPC synthetase family.

29088:TAF1B
gene id: 29088:TAF1B
uniprot id: A0A2Y9HNS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3.
messages: nucleolus

29088:GNG2
gene id: 29088:GNG2
uniprot id: A0A2Y9HZR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

29088:MPG
gene id: 29088:MPG
uniprot id: A0A2Y9HWC5
names: Function
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.
messages: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.

29088:GTF2I
gene id: 29088:GTF2I
uniprot id: A0A2Y9HX40
uniprot id: A0A2Y9HX81
uniprot id: A0A2Y9HXH9
uniprot id: A0A2Y9I255
uniprot id: A0A2Y9I3W2
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110574104
gene id: 29088:LOC110574104
uniprot id: A0A2Y9GKC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

29088:WIF1
gene id: 29088:WIF1
uniprot id: A0A2Y9G5J4
names: Caution
names: Function
messages: Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110580531
gene id: 29088:LOC110580531
uniprot id: A0A2Y9H2U0
names: Similarity
messages: Belongs to the SCC3 family.

29088:MRPL34
gene id: 29088:MRPL34
uniprot id: A0A2Y9GI86
uniprot id: A0A8M1MHZ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

29088:FZD9
gene id: 29088:FZD9
uniprot id: A0A2Y9HWI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

29088:LOC110585526
gene id: 29088:LOC110585526
uniprot id: A0A2Y9HPI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:CHMP5
gene id: 29088:CHMP5
uniprot id: A0A2Y9H6Q4
names: Similarity
messages: Belongs to the SNF7 family.

29088:LETM1
gene id: 29088:LETM1
uniprot id: A0A8M1M537
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LETM1 family.
messages: Membrane
messages: Mitochondrion inner membrane

29088:PLA2G15
gene id: 29088:PLA2G15
uniprot id: A0A2Y9I5E6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

29088:C5
gene id: 29088:C5
uniprot id: A0A2Y9HAN7
names: Subcellular Location Annotation
messages: Secreted

29088:GAB3
gene id: 29088:GAB3
uniprot id: A0A2Y9GH90
uniprot id: A0A2Y9GHB1
uniprot id: A0A2Y9GMA8
names: Similarity
messages: Belongs to the GAB family.

29088:MAP2
gene id: 29088:MAP2
uniprot id: A0A2Y9I3G8
uniprot id: A0A2Y9I3P9
uniprot id: A0A2Y9I8B3
uniprot id: A0A8M1M702
uniprot id: A0A8M1M707
uniprot id: A0A8M1M711
uniprot id: A0A8M1M716
uniprot id: A0A8M1M797
uniprot id: A0A8M1M7A1
uniprot id: A0A8M1M7A6
uniprot id: A0A8M1M7B0
uniprot id: A0A8M1M9E6
uniprot id: A0A8M1M9F1
uniprot id: A0A8M1M9F6
uniprot id: A0A8M1M9G1
uniprot id: A0A8M1MAT9
uniprot id: A0A8M1MAU4
uniprot id: A0A8M1MAU8
uniprot id: A0A8M1MAV2
uniprot id: A0A8M1MFA0
uniprot id: A0A8M1MFA5
uniprot id: A0A8M1MFB0
uniprot id: A0A8M1MFB6
names: Subcellular Location Annotation
messages: cytoskeleton

29088:TMEM18
gene id: 29088:TMEM18
uniprot id: A0A2Y9HNA6
uniprot id: A0A2Y9HTP9
uniprot id: A0A8M1MVS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM18 family.
messages: Membrane
messages: Nucleus membrane

29088:E2F2
gene id: 29088:E2F2
uniprot id: A0A2Y9GJ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

29088:PDF
gene id: 29088:PDF
uniprot id: A0A2Y9I515
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins.

29088:MADD
gene id: 29088:MADD
uniprot id: A0A2Y9GPG6
uniprot id: A0A2Y9GPK7
uniprot id: A0A8M1MR61
uniprot id: A0A8M1MSI6
uniprot id: A0A8M1MXV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MADD family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

29088:ADAM11
gene id: 29088:ADAM11
uniprot id: A0A2Y9GIJ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:NFKB2
gene id: 29088:NFKB2
uniprot id: A0A2Y9HU80
uniprot id: A0A2Y9I0L7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:NOX1
gene id: 29088:NOX1
uniprot id: A0A8M1M143
uniprot id: A0A8M1M3M7
uniprot id: A0A8M1M8X0
names: Subcellular Location Annotation
messages: Membrane

29088:SLC25A25
gene id: 29088:SLC25A25
uniprot id: A0A2Y9H6Y1
uniprot id: A0A2Y9H6Z5
uniprot id: A0A2Y9H751
uniprot id: A0A8M1MS81
uniprot id: A0A8M1MVF7
uniprot id: A0A8M1MYN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

29088:LTBP3
gene id: 29088:LTBP3
uniprot id: A0A2Y9GPS0
uniprot id: A0A2Y9GTM9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:JPT2
gene id: 29088:JPT2
uniprot id: A0A2Y9HQC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

29088:SGMS1
gene id: 29088:SGMS1
uniprot id: A0A2Y9HJM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

29088:CHMP4C
gene id: 29088:CHMP4C
uniprot id: A0A2Y9H1F3
uniprot id: A0A8M1M8R7
names: Similarity
messages: Belongs to the SNF7 family.

29088:IREB2
gene id: 29088:IREB2
uniprot id: A0A2Y9GBG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Cytoplasm
messages: RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

29088:BDNF
gene id: 29088:BDNF
uniprot id: A0A2Y9GUM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NGF-beta family.
messages: During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.
messages: Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
messages: Monomers and homodimers (By similarity). Binds to NTRK2/TRKB. Can form heterodimers with other neurotrophin family members, such as NTF3 and NTF4 (in vitro), but the physiological relevance of this is not clear (By similarity). BDNF precursor form: interacts with the heterodimer formed by NGFR and SORCS2. Mature BDNF has much lower affinity for the heterodimer formed by NGFR and SORCS2.
messages: Monomers and homodimers. Binds to NTRK2/TRKB.
messages: Secreted

29088:LOC110587764
gene id: 29088:LOC110587764
uniprot id: A0A8M1M9L3
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110582176
gene id: 29088:LOC110582176
uniprot id: A0A2Y9HDK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

29088:CLTB
gene id: 29088:CLTB
uniprot id: A0A2Y9HZ98
uniprot id: A0A8M1MIV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

29088:NT5DC3
gene id: 29088:NT5DC3
uniprot id: A0A2Y9H007
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

29088:PDE1A
gene id: 29088:PDE1A
uniprot id: A0A2Y9I3L6
uniprot id: A0A2Y9I3U5
uniprot id: A0A2Y9I8E8
uniprot id: A0A2Y9IAT7
uniprot id: A0A8M1M5Y7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

29088:GPR87
gene id: 29088:GPR87
uniprot id: A0A2Y9GQW7
uniprot id: A0A2Y9GUT3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:MACO1
gene id: 29088:MACO1
uniprot id: A0A2Y9GMU7
uniprot id: A0A8M1M7K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Plays a role in the regulation of neuronal activity.
messages: Rough endoplasmic reticulum membrane

29088:BST1
gene id: 29088:BST1
uniprot id: A0A8M1M4L8
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

29088:LOC110586228
gene id: 29088:LOC110586228
uniprot id: A0A2Y9HQX2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:OGFR
gene id: 29088:OGFR
uniprot id: A0A2Y9H6D4
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

29088:GDF9
gene id: 29088:GDF9
uniprot id: A0A2Y9I153
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: Secreted

29088:LOC110593575
gene id: 29088:LOC110593575
uniprot id: A0A2Y9I9X3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:IRX6
gene id: 29088:IRX6
uniprot id: A0A8M1MXM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

29088:CRYZ
gene id: 29088:CRYZ
uniprot id: A0A2Y9G418
uniprot id: A0A2Y9G6L0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

29088:TMEM50B
gene id: 29088:TMEM50B
uniprot id: A0A2Y9G482
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

29088:USP21
gene id: 29088:USP21
uniprot id: A0A8M1MHY4
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

29088:CSN2
gene id: 29088:CSN2
uniprot id: A0A2Y9I2E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-casein family.
messages: Important role in determination of the surface properties of the casein micelles.
messages: Secreted

29088:IPO13
gene id: 29088:IPO13
uniprot id: A0A2Y9GK07
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the importin beta family.
messages: Cytoplasm
messages: Interacts with UBC9, RAN, RBM8A, eIF-1A and PAX6.
messages: Nucleus

29088:TMEM121B
gene id: 29088:TMEM121B
uniprot id: A0A8M1MF08
names: Similarity
messages: Belongs to the TMEM121 family.

29088:RBM5
gene id: 29088:RBM5
uniprot id: A0A2Y9GTE2
uniprot id: A0A2Y9GTF3
uniprot id: A0A2Y9GXM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBM5/RBM10 family.
messages: Nucleus

29088:MEF2C
gene id: 29088:MEF2C
uniprot id: A0A2Y9HTJ5
uniprot id: A0A8M1MGG9
uniprot id: A0A8M1MGH0
uniprot id: A0A8M1MGH4
uniprot id: A0A8M1MGH6
uniprot id: A0A8M1MGH9
uniprot id: A0A8M1MGI1
uniprot id: A0A8M1MIK1
uniprot id: A0A8M1MIK6
uniprot id: A0A8M1MIL5
uniprot id: A0A8M1MJX0
uniprot id: A0A8M1MJX8
uniprot id: A0A8M1MQB1
uniprot id: A0A8M1MQB6
uniprot id: A0A8M1MQC5
names: Subcellular Location Annotation
messages: Nucleus

29088:FGF16
gene id: 29088:FGF16
uniprot id: A0A2Y9GWL2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

29088:GLOD4
gene id: 29088:GLOD4
uniprot id: A0A2Y9IEB8
uniprot id: A0A8M1MTY9
uniprot id: A0A8M1MWY4
names: Similarity
messages: Belongs to the glyoxalase I family.

29088:GSK3A
gene id: 29088:GSK3A
uniprot id: A0A2Y9H892
uniprot id: A0A8M1MVM9
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

29088:LOC110576690
gene id: 29088:LOC110576690
uniprot id: A0A8M1MQK7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

29088:NFIC
gene id: 29088:NFIC
uniprot id: A0A2Y9IAT8
uniprot id: A0A2Y9IAX5
uniprot id: A0A2Y9IBK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

29088:LOC110591064
gene id: 29088:LOC110591064
uniprot id: A0A8M1MJG6
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:LOC110571533
gene id: 29088:LOC110571533
uniprot id: A0A2Y9G8I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

29088:TNRC6C
gene id: 29088:TNRC6C
uniprot id: A0A8M1MU04
names: Similarity
messages: Belongs to the GW182 family.

29088:FGFBP3
gene id: 29088:FGFBP3
uniprot id: A0A2Y9I150
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

29088:RING1
gene id: 29088:RING1
uniprot id: A0A2Y9GM17
uniprot id: A0A2Y9GQV1
uniprot id: A0A2Y9GSF0
names: Function
names: Subcellular Location Annotation
messages: Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. Compared to RNF2/RING2, it does not have the main E3 ubiquitin ligase activity on histone H2A, and it may rather act as a modulator of RNF2/RING2 activity.
messages: Nucleus speckle

29088:IAH1
gene id: 29088:IAH1
uniprot id: A0A2Y9HNK6
uniprot id: A0A2Y9HP07
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

29088:KMT2D
gene id: 29088:KMT2D
uniprot id: A0A8M1MKI0
names: Subcellular Location Annotation
messages: Nucleus

29088:EIF4G3
gene id: 29088:EIF4G3
uniprot id: A0A2Y9GR27
uniprot id: A0A8M1M8Y9
uniprot id: A0A8M1M974
uniprot id: A0A8M1MBC7
uniprot id: A0A8M1MCQ8
uniprot id: A0A8M1MHD6
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

29088:SLC10A1
gene id: 29088:SLC10A1
uniprot id: A0A2Y9G988
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

29088:EIF1
gene id: 29088:EIF1
uniprot id: A0A8M1MUX1
names: Similarity
messages: Belongs to the SUI1 family.

29088:AKR1B1
gene id: 29088:AKR1B1
uniprot id: A0A2Y9HFK0
uniprot id: A0A8M1MU12
names: Similarity
messages: Belongs to the aldo/keto reductase family.

29088:PRKD3
gene id: 29088:PRKD3
uniprot id: A0A2Y9HN24
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

29088:SUMF1
gene id: 29088:SUMF1
uniprot id: A0A2Y9HFT7
uniprot id: A0A2Y9HG32
uniprot id: A0A8M1MF95
uniprot id: A0A8M1MIS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

29088:LOC110579984
gene id: 29088:LOC110579984
uniprot id: A0A2Y9H7P0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

29088:TLX3
gene id: 29088:TLX3
uniprot id: A0A2Y9HX65
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110575877
gene id: 29088:LOC110575877
uniprot id: A0A2Y9GRX0
names: Similarity
messages: Belongs to the peptidase A1 family.

29088:LOC110581670
gene id: 29088:LOC110581670
uniprot id: A0A2Y9HDA6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC123324583
gene id: 29088:LOC123324583
uniprot id: A0A2Y9GD22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:RACK1
gene id: 29088:RACK1
uniprot id: A0A2Y9H8K1
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

29088:PDSS1
gene id: 29088:PDSS1
uniprot id: A0A2Y9GUA6
uniprot id: A0A8M1MKT1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

29088:CREG2
gene id: 29088:CREG2
uniprot id: A0A2Y9GD23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

29088:PRF1
gene id: 29088:PRF1
uniprot id: A0A2Y9GB24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

29088:ROGDI
gene id: 29088:ROGDI
uniprot id: A0A2Y9HQG9
uniprot id: A0A2Y9HQT8
uniprot id: A0A2Y9HX99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rogdi family.
messages: Perikaryon
messages: Presynapse
messages: synaptic vesicle

29088:LOC110591707
gene id: 29088:LOC110591707
uniprot id: A0A8M1MW53
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

29088:INTS14
gene id: 29088:INTS14
uniprot id: A0A2Y9HCH2
uniprot id: A0A2Y9HCT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INTS14 family.
messages: Nucleus
messages: Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.

29088:PIK3CG
gene id: 29088:PIK3CG
uniprot id: A0A2Y9GHI7
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

29088:ZFP36L2
gene id: 29088:ZFP36L2
uniprot id: A0A2Y9HZ35
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

29088:LOC110582755
gene id: 29088:LOC110582755
uniprot id: A0A2Y9H9P0
names: Similarity
names: Subunit
messages: Belongs to the PIP family.
messages: Monomer. Interacts with AZGP1.

29088:LOC123324332
gene id: 29088:LOC123324332
uniprot id: A0A8M1M712
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

29088:ACLY
gene id: 29088:ACLY
uniprot id: A0A2Y9GEH7
uniprot id: A0A2Y9GEM0
uniprot id: A0A2Y9GJ20
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

29088:LOC110582119
gene id: 29088:LOC110582119
uniprot id: A0A8M1M2G9
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

29088:NOX4
gene id: 29088:NOX4
uniprot id: A0A2Y9G6W1
uniprot id: A0A2Y9G9C6
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110581518
gene id: 29088:LOC110581518
uniprot id: A0A2Y9H600
uniprot id: A0A8M1MYK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

29088:LOC110588598
gene id: 29088:LOC110588598
uniprot id: A0A8M1M686
names: Function
names: Similarity
messages: Belongs to the CDC123 family.
messages: Required for S phase entry of the cell cycle.

29088:LOC110587656
gene id: 29088:LOC110587656
uniprot id: A0A8M1M8S8
names: Function
names: Similarity
names: Subunit
messages: Component of the 40S subunit of the ribosome.
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Ribosomal protein S27a is part of the 40S ribosomal subunit.

29088:LOC110571813
gene id: 29088:LOC110571813
uniprot id: A0A8M1M878
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.

29088:TMEM255A
gene id: 29088:TMEM255A
uniprot id: A0A2Y9GR80
uniprot id: A0A2Y9GWY0
uniprot id: A0A2Y9GWZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

29088:GPN2
gene id: 29088:GPN2
uniprot id: A0A2Y9GPL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

29088:LOC110583577
gene id: 29088:LOC110583577
uniprot id: A0A8M1MJX1
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110587554
gene id: 29088:LOC110587554
uniprot id: A0A8M1MM43
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

29088:LOC110586801
gene id: 29088:LOC110586801
uniprot id: A0A2Y9HMC8
uniprot id: A0A2Y9HTT8
uniprot id: A0A8M1ML56
names: Subcellular Location Annotation
messages: Nucleus

29088:PTP4A3
gene id: 29088:PTP4A3
uniprot id: A0A2Y9GXW6
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

29088:SYBU
gene id: 29088:SYBU
uniprot id: A0A2Y9H377
uniprot id: A0A8M1MCE3
names: Subcellular Location Annotation
messages: Membrane

29088:ALOX12
gene id: 29088:ALOX12
uniprot id: A0A2Y9HEX4
uniprot id: A0A2Y9HF10
uniprot id: A0A2Y9HF16
uniprot id: A0A2Y9HFC1
uniprot id: A0A2Y9HLA9
uniprot id: A0A2Y9HLD6
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:EEF1AKMT2
gene id: 29088:EEF1AKMT2
uniprot id: A0A2Y9I6Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: Nucleus
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'.

29088:CHRM2
gene id: 29088:CHRM2
uniprot id: A0A2Y9HGZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

29088:LOC110579082
gene id: 29088:LOC110579082
uniprot id: A0A8M1MGW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

29088:ZHX3
gene id: 29088:ZHX3
uniprot id: A0A2Y9GZF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

29088:LOC110591949
gene id: 29088:LOC110591949
uniprot id: A0A2Y9IB16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STK11IP family.
messages: Cytoplasm

29088:TMBIM4
gene id: 29088:TMBIM4
uniprot id: A0A2Y9G5Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

29088:SPR
gene id: 29088:SPR
uniprot id: A0A2Y9HTH7
names: Similarity
messages: Belongs to the sepiapterin reductase family.

29088:LOC110589270
gene id: 29088:LOC110589270
uniprot id: A0A2Y9I003
uniprot id: A0A8M1MG13
uniprot id: A0A8M1MMK2
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

29088:AFF3
gene id: 29088:AFF3
uniprot id: A0A8M1MP74
names: Similarity
messages: Belongs to the AF4 family.

29088:LOC110576318
gene id: 29088:LOC110576318
uniprot id: A0A2Y9GPK8
names: Subcellular Location Annotation
messages: Membrane

29088:RNF2
gene id: 29088:RNF2
uniprot id: A0A2Y9GGI4
names: Subcellular Location Annotation
messages: Chromosome
messages: Cytoplasm

29088:TYRO3
gene id: 29088:TYRO3
uniprot id: A0A2Y9HHN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane
messages: Membrane

29088:CRH
gene id: 29088:CRH
uniprot id: A0A2Y9GYF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

29088:ACAP2
gene id: 29088:ACAP2
uniprot id: A0A2Y9H8P8
uniprot id: A0A8M1MSY6
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

29088:CNIH3
gene id: 29088:CNIH3
uniprot id: A0A2Y9G805
uniprot id: A0A2Y9GAP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

29088:LOC110576459
gene id: 29088:LOC110576459
uniprot id: A0A8M1MPC8
names: Subcellular Location Annotation
messages: Membrane

29088:ERCC3
gene id: 29088:ERCC3
uniprot id: A0A2Y9HIQ3
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

29088:TIMP2
gene id: 29088:TIMP2
uniprot id: A0A2Y9GC89
names: Similarity
names: Subunit
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: Interacts (via the C-terminal) with MMP2 (via the C-terminal PEX domain); the interaction inhibits the MMP2 activity.

29088:EI24
gene id: 29088:EI24
uniprot id: A0A2Y9HJT0
uniprot id: A0A2Y9HQF3
uniprot id: A0A2Y9HR55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EI24 family.
messages: Membrane

29088:SLC66A3
gene id: 29088:SLC66A3
uniprot id: A0A2Y9HNQ9
uniprot id: A0A2Y9HP13
uniprot id: A0A8M1MLT2
names: Subcellular Location Annotation
messages: Membrane

29088:ICAM1
gene id: 29088:ICAM1
uniprot id: A0A2Y9IAX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

29088:LOC123325498
gene id: 29088:LOC123325498
uniprot id: A0A8M1MJK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:DNAJC10
gene id: 29088:DNAJC10
uniprot id: A0A2Y9I4U2
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.
messages: Endoplasmic reticulum lumen

29088:NRG4
gene id: 29088:NRG4
uniprot id: A0A8M1MK59
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:CCR7
gene id: 29088:CCR7
uniprot id: A0A2Y9I7F6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:FBN1
gene id: 29088:FBN1
uniprot id: A0A2Y9HJ86
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:AVIL
gene id: 29088:AVIL
uniprot id: A0A2Y9GUT7
names: Similarity
messages: Belongs to the villin/gelsolin family.

29088:GPX2
gene id: 29088:GPX2
uniprot id: A0A2Y9I497
names: Similarity
messages: Belongs to the glutathione peroxidase family.

29088:MCM8
gene id: 29088:MCM8
uniprot id: A0A2Y9GZ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

29088:LOC110589015
gene id: 29088:LOC110589015
uniprot id: A0A2Y9HYY1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

29088:BARHL2
gene id: 29088:BARHL2
uniprot id: A0A2Y9H2U8
names: Subcellular Location Annotation
messages: Nucleus

29088:PABIR3
gene id: 29088:PABIR3
uniprot id: A0A8M1M4E2
names: Similarity
messages: Belongs to the FAM122 family.

29088:CSTF2T
gene id: 29088:CSTF2T
uniprot id: A0A2Y9HJD4
uniprot id: A0A8M1MDP7
uniprot id: A0A8M1MFR6
uniprot id: A0A8M1MH55
uniprot id: A0A8M1MM94
names: Subcellular Location Annotation
messages: Nucleus

29088:TTC36
gene id: 29088:TTC36
uniprot id: A0A2Y9HKJ3
names: Similarity
messages: Belongs to the TTC36 family.

29088:HACL1
gene id: 29088:HACL1
uniprot id: A0A2Y9G9K2
names: Similarity
messages: Belongs to the TPP enzyme family.

29088:SLC26A1
gene id: 29088:SLC26A1
uniprot id: A0A2Y9G589
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate.
messages: Membrane

29088:MS4A1
gene id: 29088:MS4A1
uniprot id: A0A2Y9GN48
names: Similarity
messages: Belongs to the MS4A family.

29088:TNFSF11
gene id: 29088:TNFSF11
uniprot id: A0A2Y9HW80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

29088:LOC110571238
gene id: 29088:LOC110571238
uniprot id: A0A8M1M7T7
names: Similarity
messages: Belongs to the GroES chaperonin family.

29088:PSMD9
gene id: 29088:PSMD9
uniprot id: A0A2Y9HWC6
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

29088:LOC110577330
gene id: 29088:LOC110577330
uniprot id: A0A2Y9GYG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

29088:ATL3
gene id: 29088:ATL3
uniprot id: A0A2Y9GTI6
uniprot id: A0A8M1MPU5
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

29088:GPHN
gene id: 29088:GPHN
uniprot id: A0A8M1MJP1
uniprot id: A0A8M1MJP4
uniprot id: A0A8M1MJP6
uniprot id: A0A8M1MJP9
uniprot id: A0A8M1MLQ1
uniprot id: A0A8M1MLQ6
uniprot id: A0A8M1MN18
uniprot id: A0A8M1MTR1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
messages: In the C-terminal section; belongs to the MoeA family.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

29088:LOC110576448
gene id: 29088:LOC110576448
uniprot id: A0A2Y9GVP0
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110577716
gene id: 29088:LOC110577716
uniprot id: A0A8M1MEG5
names: Similarity
messages: Belongs to the CDK2AP family.

29088:LOC110575558
gene id: 29088:LOC110575558
uniprot id: A0A8M1MHF1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

29088:DRC1
gene id: 29088:DRC1
uniprot id: A0A8M1MVC6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DRC1 family.
messages: Component of the nexin-dynein regulatory complex (N-DRC).
messages: cilium axoneme
messages: flagellum axoneme

29088:SRP19
gene id: 29088:SRP19
uniprot id: A0A2Y9HXL6
uniprot id: A0A8M1MJC1
uniprot id: A0A8M1MPQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP19 family.
messages: Cytoplasm

29088:TMEM211
gene id: 29088:TMEM211
uniprot id: A0A8M1MTG8
names: Subcellular Location Annotation
messages: Membrane

29088:CDH24
gene id: 29088:CDH24
uniprot id: A0A2Y9HH52
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

29088:SLC43A1
gene id: 29088:SLC43A1
uniprot id: A0A2Y9GN09
uniprot id: A0A8M1MRJ1
names: Subcellular Location Annotation
messages: Membrane

29088:HOGA1
gene id: 29088:HOGA1
uniprot id: A0A2Y9HZ73
uniprot id: A0A2Y9I0Q9
uniprot id: A0A8M1MP03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the final step in the metabolic pathway of hydroxyproline.
messages: Homotetramer.

29088:LOC110590062
gene id: 29088:LOC110590062
uniprot id: A0A2Y9HXM6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

29088:KIF25
gene id: 29088:KIF25
uniprot id: A0A2Y9HHK0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:CLDN5
gene id: 29088:CLDN5
uniprot id: A0A2Y9HB61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

29088:HK2
gene id: 29088:HK2
uniprot id: A0A2Y9HTM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hexokinase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: cytosol

29088:RPL24
gene id: 29088:RPL24
uniprot id: A0A2Y9HFG7
uniprot id: A0A8M1MQZ5
uniprot id: A0A8M1MSB5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

29088:LOC110591245
gene id: 29088:LOC110591245
uniprot id: A0A8M1MG01
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:SUV39H1
gene id: 29088:SUV39H1
uniprot id: A0A2Y9G6H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Nucleus
messages: centromere

29088:SLC7A3
gene id: 29088:SLC7A3
uniprot id: A0A2Y9GAS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

29088:CLDN15
gene id: 29088:CLDN15
uniprot id: A0A2Y9H932
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

29088:IFIH1
gene id: 29088:IFIH1
uniprot id: A0A8M1M5V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

29088:SF3B4
gene id: 29088:SF3B4
uniprot id: A0A2Y9GX12
uniprot id: A0A8M1MC04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus

29088:PLIN3
gene id: 29088:PLIN3
uniprot id: A0A2Y9IAK2
uniprot id: A0A2Y9IAM5
names: Similarity
messages: Belongs to the perilipin family.

29088:LOC110584080
gene id: 29088:LOC110584080
uniprot id: A0A8M1MDJ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion intermembrane space

29088:HYAL3
gene id: 29088:HYAL3
uniprot id: A0A2Y9GTR8
uniprot id: A0A2Y9GTX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Early endosome
messages: Endoplasmic reticulum
messages: Endosome
messages: Membrane
messages: acrosome

29088:CUBN
gene id: 29088:CUBN
uniprot id: A0A2Y9HL15
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

29088:KIF7
gene id: 29088:KIF7
uniprot id: A0A8M1MJ96
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:TMED6
gene id: 29088:TMED6
uniprot id: A0A2Y9I4Y3
uniprot id: A0A8M1MXL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:FLT4
gene id: 29088:FLT4
uniprot id: A0A2Y9H8L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Nucleus

29088:UPP1
gene id: 29088:UPP1
uniprot id: A0A2Y9I5W6
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

29088:LOC110587786
gene id: 29088:LOC110587786
uniprot id: A0A2Y9HPI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the globin family.
messages: Heterotetramer of two alpha chains and two beta chains.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.

29088:LOC110572103
gene id: 29088:LOC110572103
uniprot id: A0A8M1MBZ1
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

29088:SRPX
gene id: 29088:SRPX
uniprot id: A0A2Y9GED2
uniprot id: A0A2Y9GH91
uniprot id: A0A2Y9GIQ7
uniprot id: A0A8M1M5B6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:CHD8
gene id: 29088:CHD8
uniprot id: A0A2Y9HIH9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. CHD8 subfamily.
messages: DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive genes. Involved in both enhancer blocking and epigenetic remodeling at chromatin boundary via its interaction with CTCF. Acts as a suppressor of STAT3 activity by suppressing the LIF-induced STAT3 transcriptional activity. Also acts as a transcription activator via its interaction with ZNF143 by participating in efficient U6 RNA polymerase III transcription.
messages: Interacts with p53/TP53, histone H1, CTNNB1, CTCF and PIAS3. Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, KAT8/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Interacts with CHD7. Interacts with FAM124B.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Sumoylated.

29088:GABRA2
gene id: 29088:GABRA2
uniprot id: A0A8M1M6M3
uniprot id: A0A8M1M836
uniprot id: A0A8M1MC54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: dendrite

29088:MIOS
gene id: 29088:MIOS
uniprot id: A0A2Y9H0X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat mio family.
messages: Lysosome membrane

29088:MMAA
gene id: 29088:MMAA
uniprot id: A0A2Y9GB32
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

29088:ADORA1
gene id: 29088:ADORA1
uniprot id: A0A2Y9GSN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

29088:LOC110586781
gene id: 29088:LOC110586781
uniprot id: A0A8M1MK21
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:RIN2
gene id: 29088:RIN2
uniprot id: A0A2Y9HXG9
uniprot id: A0A2Y9I2G7
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

29088:RTBDN
gene id: 29088:RTBDN
uniprot id: A0A2Y9IIB0
names: Similarity
messages: Belongs to the folate receptor family.

29088:CLIC3
gene id: 29088:CLIC3
uniprot id: A0A8M1MU99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

29088:UBE2A
gene id: 29088:UBE2A
uniprot id: A0A2Y9GRI0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:GPN1
gene id: 29088:GPN1
uniprot id: A0A2Y9HMP0
uniprot id: A0A2Y9HN47
uniprot id: A0A2Y9HT46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

29088:LOC110590313
gene id: 29088:LOC110590313
uniprot id: A0A2Y9I5B6
names: Subcellular Location Annotation
messages: Nucleus

29088:PTGES3
gene id: 29088:PTGES3
uniprot id: A0A2Y9H0E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p23/wos2 family.
messages: Cytoplasm
messages: Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation.
messages: Forms a complex with HSP70, HSP90 and other chaperones.

29088:KCNS3
gene id: 29088:KCNS3
uniprot id: A0A2Y9HTG3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:LOC110584821
gene id: 29088:LOC110584821
uniprot id: A0A8M1MYY7
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

29088:PM20D2
gene id: 29088:PM20D2
uniprot id: A0A2Y9HBT5
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Catalyzes the peptide bond hydrolysis in dipeptides having basic amino acids lysine, ornithine or arginine at C-terminus.

29088:PTK6
gene id: 29088:PTK6
uniprot id: A0A8M1MPB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

29088:CYFIP1
gene id: 29088:CYFIP1
uniprot id: A0A2Y9GB86
uniprot id: A0A2Y9GBE7
names: Similarity
messages: Belongs to the CYFIP family.

29088:BCHE
gene id: 29088:BCHE
uniprot id: A0A2Y9I3F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

29088:LSM5
gene id: 29088:LSM5
uniprot id: A0A2Y9H179
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

29088:NINJ1
gene id: 29088:NINJ1
uniprot id: A0A2Y9HKI9
uniprot id: A0A2Y9HKQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

29088:LOC110586922
gene id: 29088:LOC110586922
uniprot id: A0A8M1MR15
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

29088:LOC110583988
gene id: 29088:LOC110583988
uniprot id: A0A8M1MJY2
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

29088:EIF3F
gene id: 29088:EIF3F
uniprot id: A0A2Y9GQ43
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit F family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.

29088:DPY19L3
gene id: 29088:DPY19L3
uniprot id: A0A2Y9I3A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

29088:RALYL
gene id: 29088:RALYL
uniprot id: A0A2Y9H3M2
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

29088:USP24
gene id: 29088:USP24
uniprot id: A0A2Y9GQ91
names: Similarity
messages: Belongs to the peptidase C19 family.

29088:LAMB2
gene id: 29088:LAMB2
uniprot id: A0A2Y9GTL1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

29088:CDKN1C
gene id: 29088:CDKN1C
uniprot id: A0A2Y9GUB3
names: Similarity
messages: Belongs to the CDI family.

29088:CAPNS1
gene id: 29088:CAPNS1
uniprot id: A0A2Y9HY18
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer or heterodimer of a large (catalytic) and a small (regulatory) subunit. In presence of calcium, the heterodimer dissociates.
messages: Membrane

29088:LOC110573980
gene id: 29088:LOC110573980
uniprot id: A0A2Y9GJV7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:UNCX
gene id: 29088:UNCX
uniprot id: A0A2Y9GA25
names: Subcellular Location Annotation
messages: Nucleus

29088:SF3B5
gene id: 29088:SF3B5
uniprot id: A0A2Y9HGP5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

29088:GRK3
gene id: 29088:GRK3
uniprot id: A0A8M1MYZ4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

29088:ESR2
gene id: 29088:ESR2
uniprot id: A0A2Y9I4H2
uniprot id: A0A2Y9I6C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

29088:LOC110580499
gene id: 29088:LOC110580499
uniprot id: A0A2Y9H7Q2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

29088:TREX2
gene id: 29088:TREX2
uniprot id: A0A2Y9GHU5
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

29088:ADGRB2
gene id: 29088:ADGRB2
uniprot id: A0A8M1M7X2
names: Subcellular Location Annotation
messages: Membrane

29088:PANX1
gene id: 29088:PANX1
uniprot id: A0A2Y9G6U7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: S-nitrosylation inhibits channel currents and ATP release.
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

29088:ELK3
gene id: 29088:ELK3
uniprot id: A0A2Y9GVF1
uniprot id: A0A2Y9GVI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

29088:FAM193B
gene id: 29088:FAM193B
uniprot id: A0A2Y9HZC6
uniprot id: A0A8M1MIU3
uniprot id: A0A8M1MQL5
names: Similarity
messages: Belongs to the FAM193 family.

29088:CCDC124
gene id: 29088:CCDC124
uniprot id: A0A2Y9GLF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CCDC124 family.
messages: Interacts with RASGEF1B.
messages: Required for proper progression of late cytokinetic stages.

29088:FUZ
gene id: 29088:FUZ
uniprot id: A0A2Y9GDD9
uniprot id: A0A2Y9GHS4
uniprot id: A0A8M1M0P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fuzzy family.
messages: cytoskeleton

29088:ACTR3
gene id: 29088:ACTR3
uniprot id: A0A2Y9HIX3
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

29088:AGAP1
gene id: 29088:AGAP1
uniprot id: A0A2Y9G6R0
uniprot id: A0A8M1MFG9
names: Similarity
messages: Belongs to the centaurin gamma-like family.

29088:PLSCR1
gene id: 29088:PLSCR1
uniprot id: A0A2Y9H9K0
uniprot id: A0A8M1MBN0
uniprot id: A0A8M1MDQ7
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

29088:LOC123325298
gene id: 29088:LOC123325298
uniprot id: A0A8M1MGL1
names: Subcellular Location Annotation
messages: Nucleus

29088:PI4KA
gene id: 29088:PI4KA
uniprot id: A0A2Y9H0J0
uniprot id: A0A2Y9H2I5
uniprot id: A0A8M1MTB5
uniprot id: A0A8M1MTB8
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

29088:SURF4
gene id: 29088:SURF4
uniprot id: A0A2Y9H593
uniprot id: A0A8M1MQV3
uniprot id: A0A8M1MU37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

29088:PUS10
gene id: 29088:PUS10
uniprot id: A0A8M1MMZ0
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

29088:CUZD1
gene id: 29088:CUZD1
uniprot id: A0A2Y9I626
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:TOPAZ1
gene id: 29088:TOPAZ1
uniprot id: A0A2Y9G2F2
names: Function
names: Subcellular Location Annotation
messages: Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear.
messages: cytosol

29088:L3MBTL3
gene id: 29088:L3MBTL3
uniprot id: A0A8M1MLS3
uniprot id: A0A8M1MSD7
names: Subcellular Location Annotation
messages: Nucleus

29088:VWCE
gene id: 29088:VWCE
uniprot id: A0A2Y9GMY8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:HSD17B3
gene id: 29088:HSD17B3
uniprot id: A0A2Y9G3Z7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:LOC110573349
gene id: 29088:LOC110573349
uniprot id: A0A8M1MEC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SLC23A1
gene id: 29088:SLC23A1
uniprot id: A0A2Y9I1W1
uniprot id: A0A8M1MPD2
names: Subcellular Location Annotation
messages: Membrane

29088:LRP1
gene id: 29088:LRP1
uniprot id: A0A2Y9H087
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:LOC110589872
gene id: 29088:LOC110589872
uniprot id: A0A2Y9HX36
uniprot id: A0A2Y9I200
uniprot id: A0A8M1MCP5
uniprot id: A0A8M1MCU5
uniprot id: A0A8M1MGB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

29088:SNTB1
gene id: 29088:SNTB1
uniprot id: A0A2Y9GYL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

29088:TAF11
gene id: 29088:TAF11
uniprot id: A0A2Y9GM16
uniprot id: A0A2Y9GMA9
names: Similarity
messages: Belongs to the TAF11 family.

29088:ATP8A1
gene id: 29088:ATP8A1
uniprot id: A0A8M1M4Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

29088:DHRS9
gene id: 29088:DHRS9
uniprot id: A0A2Y9I548
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:RSAD1
gene id: 29088:RSAD1
uniprot id: A0A2Y9ICE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Mitochondrion

29088:EDN1
gene id: 29088:EDN1
uniprot id: A0A2Y9HLU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

29088:LOC110587327
gene id: 29088:LOC110587327
uniprot id: A0A8M1MP97
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

29088:TSC22D1
gene id: 29088:TSC22D1
uniprot id: A0A2Y9HP99
uniprot id: A0A2Y9HUE8
uniprot id: A0A2Y9HVW8
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

29088:TMEM30B
gene id: 29088:TMEM30B
uniprot id: A0A2Y9HZK5
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

29088:LOC110580241
gene id: 29088:LOC110580241
uniprot id: A0A2Y9H6V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ATP5IF1
gene id: 29088:ATP5IF1
uniprot id: A0A8M1MFX5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

29088:HOXA6
gene id: 29088:HOXA6
uniprot id: A0A2Y9H0W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

29088:UCP3
gene id: 29088:UCP3
uniprot id: A0A2Y9IFW2
uniprot id: A0A8M1MPL9
uniprot id: A0A8M1MQX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:KLHL22
gene id: 29088:KLHL22
uniprot id: A0A2Y9GWB7
uniprot id: A0A2Y9H2T8
names: Subcellular Location Annotation
messages: Lysosome
messages: Nucleus
messages: centrosome
messages: cytosol
messages: spindle

29088:LOC110578912
gene id: 29088:LOC110578912
uniprot id: A0A8M1M8Q2
names: Similarity
names: Subunit
messages: AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or PRKAG3). Interacts with FNIP1 and FNIP2.
messages: Belongs to the 5'-AMP-activated protein kinase gamma subunit family.

29088:SLC26A2
gene id: 29088:SLC26A2
uniprot id: A0A2Y9HLY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Cell membrane
messages: Membrane
messages: Sulfate transporter. May play a role in endochondral bone formation.

29088:STK38
gene id: 29088:STK38
uniprot id: A0A2Y9GM92
uniprot id: A0A8M1MJW4
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:GATA6
gene id: 29088:GATA6
uniprot id: A0A2Y9GXB1
names: Subcellular Location Annotation
messages: Nucleus

29088:PTPRA
gene id: 29088:PTPRA
uniprot id: A0A2Y9GZV8
uniprot id: A0A2Y9GZW8
uniprot id: A0A2Y9H6A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

29088:NT5E
gene id: 29088:NT5E
uniprot id: A0A2Y9HBF2
uniprot id: A0A8M1MKZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-nucleotidase family.
messages: Membrane

29088:CLVS1
gene id: 29088:CLVS1
uniprot id: A0A2Y9H4S8
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network membrane

29088:NRXN2
gene id: 29088:NRXN2
uniprot id: A0A2Y9GTV9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:AWAT1
gene id: 29088:AWAT1
uniprot id: A0A2Y9GAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane

29088:CLDN34
gene id: 29088:CLDN34
uniprot id: A0A2Y9G2D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

29088:LOC110578480
gene id: 29088:LOC110578480
uniprot id: A0A8M1M920
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

29088:RAB4B
gene id: 29088:RAB4B
uniprot id: A0A2Y9I372
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

29088:OGFRL1
gene id: 29088:OGFRL1
uniprot id: A0A2Y9H7Q0
uniprot id: A0A2Y9H7Y3
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

29088:NMUR2
gene id: 29088:NMUR2
uniprot id: A0A2Y9HMR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

29088:GLRA1
gene id: 29088:GLRA1
uniprot id: A0A2Y9HSV7
uniprot id: A0A2Y9HU70
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite

29088:RAD21
gene id: 29088:RAD21
uniprot id: A0A2Y9GYX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

29088:SLC46A3
gene id: 29088:SLC46A3
uniprot id: A0A2Y9G4I9
names: Subcellular Location Annotation
messages: Membrane

29088:ADGRV1
gene id: 29088:ADGRV1
uniprot id: A0A8M1MHV4
names: Subcellular Location Annotation
messages: Membrane

29088:FAM131A
gene id: 29088:FAM131A
uniprot id: A0A2Y9H8M3
uniprot id: A0A2Y9HE55
uniprot id: A0A2Y9HF74
names: Similarity
messages: Belongs to the FAM131 family.

29088:PNRC2
gene id: 29088:PNRC2
uniprot id: A0A2Y9GMT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNRC family. PNRC2 subfamily.
messages: Nucleus
messages: P-body

29088:GLYCTK
gene id: 29088:GLYCTK
uniprot id: A0A2Y9HGB0
names: Similarity
messages: Belongs to the glycerate kinase type-2 family.

29088:SYNE4
gene id: 29088:SYNE4
uniprot id: A0A2Y9HY02
uniprot id: A0A2Y9I2W5
names: Similarity
messages: Belongs to the nesprin family.

29088:MAOA
gene id: 29088:MAOA
uniprot id: A0A2Y9GHV8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flavin monoamine oxidase family.
messages: Mitochondrion outer membrane
messages: Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer.

29088:LOC110581020
gene id: 29088:LOC110581020
uniprot id: A0A2Y9H451
names: Function
names: Similarity
messages: Belongs to the calcitonin family.
messages: Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.

29088:ALCAM
gene id: 29088:ALCAM
uniprot id: A0A2Y9H8M2
uniprot id: A0A2Y9H8Q1
uniprot id: A0A2Y9H8Q6
uniprot id: A0A2Y9H8U3
uniprot id: A0A2Y9HED7
names: Subcellular Location Annotation
messages: Cell membrane
messages: axon
messages: dendrite

29088:NDUFA3
gene id: 29088:NDUFA3
uniprot id: A0A2Y9GJ97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA3 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Membrane
messages: Mitochondrion inner membrane

29088:B4GALT2
gene id: 29088:B4GALT2
uniprot id: A0A2Y9GK12
uniprot id: A0A8M1MG62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

29088:POU5F2
gene id: 29088:POU5F2
uniprot id: A0A2Y9I0H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-5 subfamily.
messages: Nucleus

29088:POPDC2
gene id: 29088:POPDC2
uniprot id: A0A2Y9H956
uniprot id: A0A8M1M8G2
names: Similarity
messages: Belongs to the popeye family.

29088:PDE9A
gene id: 29088:PDE9A
uniprot id: A0A8M1MQ98
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

29088:PIH1D2
gene id: 29088:PIH1D2
uniprot id: A0A2Y9HK85
uniprot id: A0A8M1MQZ4
names: Similarity
messages: Belongs to the PIH1 family.

29088:CRYAA
gene id: 29088:CRYAA
uniprot id: A0A2Y9G7B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Contributes to the transparency and refractive index of the lens. Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
messages: Cytoplasm
messages: Heteromer composed of three CRYAA and one CRYAB subunits. Inter-subunit bridging via zinc ions enhances stability, which is crucial as there is no protein turn over in the lens. Can also form homodimers and homotetramers (dimers of dimers) which serve as the building blocks of homooligomers (By similarity). Within homooligomers, the zinc-binding motif is created from residues of 3 different molecules. His-100 and Glu-102 from one molecule are ligands of the zinc ion, and His-107 and His-154 residues from additional molecules complete the site with tetrahedral coordination geometry (By similarity). Part of a complex required for lens intermediate filament formation composed of BFSP1, BFSP2 and CRYAA.
messages: May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
messages: Nucleus

29088:BMS1
gene id: 29088:BMS1
uniprot id: A0A2Y9HW12
names: Subcellular Location Annotation
messages: nucleolus

29088:PTGR1
gene id: 29088:PTGR1
uniprot id: A0A2Y9H614
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer or homodimer.

29088:CCL21
gene id: 29088:CCL21
uniprot id: A0A2Y9H5C0
uniprot id: A0A2Y9H5D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

29088:MELTF
gene id: 29088:MELTF
uniprot id: A0A2Y9H9J1
names: Similarity
messages: Belongs to the transferrin family.

29088:RARS2
gene id: 29088:RARS2
uniprot id: A0A2Y9HAW2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

29088:IQCD
gene id: 29088:IQCD
uniprot id: A0A2Y9HRG5
uniprot id: A0A2Y9HRW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC10 family.
messages: Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
messages: flagellum axoneme

29088:LOC110572739
gene id: 29088:LOC110572739
uniprot id: A0A2Y9GCR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNF-like-inhibitor family.
messages: Secreted

29088:CCND1
gene id: 29088:CCND1
uniprot id: A0A2Y9GVJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Nucleus

29088:LOC123323281
gene id: 29088:LOC123323281
uniprot id: A0A8M1M4J2
uniprot id: A0A8M1M869
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

29088:PPP1R14B
gene id: 29088:PPP1R14B
uniprot id: A0A2Y9GS66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Inhibitor of PPP1CA.
messages: Membrane

29088:MCM10
gene id: 29088:MCM10
uniprot id: A0A2Y9HL10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

29088:RASGRP4
gene id: 29088:RASGRP4
uniprot id: A0A2Y9HXQ3
names: Similarity
messages: Belongs to the RASGRP family.

29088:PSMA3
gene id: 29088:PSMA3
uniprot id: A0A2Y9HZH2
uniprot id: A0A2Y9HZS7
uniprot id: A0A8M1MJ01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

29088:METAP1D
gene id: 29088:METAP1D
uniprot id: A0A2Y9I3K4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

29088:ALG14
gene id: 29088:ALG14
uniprot id: A0A2Y9H7S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG14 family.
messages: Membrane
messages: Nucleus membrane

29088:LOC110571795
gene id: 29088:LOC110571795
uniprot id: A0A2Y9G9J9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription coregulator that can have both coactivator and corepressor functions.
messages: centromere
messages: kinetochore

29088:SUGT1
gene id: 29088:SUGT1
uniprot id: A0A2Y9HPB1
uniprot id: A0A8M1M9C2
names: Similarity
messages: Belongs to the SGT1 family.

29088:BDKRB2
gene id: 29088:BDKRB2
uniprot id: A0A2Y9GC61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

29088:OSMR
gene id: 29088:OSMR
uniprot id: A0A2Y9HXE3
uniprot id: A0A8M1MGY4
uniprot id: A0A8M1MGY7
uniprot id: A0A8M1MJ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

29088:ELL3
gene id: 29088:ELL3
uniprot id: A0A8M1MIQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

29088:SATB1
gene id: 29088:SATB1
uniprot id: A0A2Y9G624
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

29088:LYPLAL1
gene id: 29088:LYPLAL1
uniprot id: A0A8M1MN68
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

29088:SLC35C2
gene id: 29088:SLC35C2
uniprot id: A0A2Y9GZC2
uniprot id: A0A2Y9GZC5
names: Subcellular Location Annotation
messages: Membrane

29088:KIF26A
gene id: 29088:KIF26A
uniprot id: A0A8M1MJF5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:NOS2
gene id: 29088:NOS2
uniprot id: A0A2Y9IBE4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.

29088:PLXNA2
gene id: 29088:PLXNA2
uniprot id: A0A2Y9GGC9
uniprot id: A0A8M1MNC1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:SENP1
gene id: 29088:SENP1
uniprot id: A0A2Y9IDL1
names: Similarity
messages: Belongs to the peptidase C48 family.

29088:CMTM7
gene id: 29088:CMTM7
uniprot id: A0A8M1MD38
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110572022
gene id: 29088:LOC110572022
uniprot id: A0A2Y9GE77
uniprot id: A0A8M1MMU2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

29088:CACNA1G
gene id: 29088:CACNA1G
uniprot id: A0A2Y9I6H5
uniprot id: A0A2Y9I6I1
uniprot id: A0A2Y9I6I7
uniprot id: A0A2Y9I6J2
uniprot id: A0A2Y9I6J8
uniprot id: A0A2Y9I6K3
uniprot id: A0A2Y9I6K8
uniprot id: A0A2Y9I6W2
uniprot id: A0A2Y9I6W7
uniprot id: A0A2Y9I6X2
uniprot id: A0A2Y9I6X8
uniprot id: A0A2Y9I6Y3
uniprot id: A0A2Y9I7B5
uniprot id: A0A2Y9I7B8
uniprot id: A0A2Y9I7C2
uniprot id: A0A2Y9I7C8
uniprot id: A0A2Y9I7D2
uniprot id: A0A2Y9I7D8
uniprot id: A0A2Y9IBA6
uniprot id: A0A2Y9IBB1
uniprot id: A0A2Y9IBC1
uniprot id: A0A2Y9IBC6
uniprot id: A0A2Y9IBD1
uniprot id: A0A2Y9IDY3
uniprot id: A0A2Y9IDY8
uniprot id: A0A2Y9IDZ3
uniprot id: A0A2Y9IDZ9
uniprot id: A0A2Y9IE04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.

29088:CDKN2AIPNL
gene id: 29088:CDKN2AIPNL
uniprot id: A0A2Y9I125
names: Similarity
messages: Belongs to the CARF family.

29088:PGAP1
gene id: 29088:PGAP1
uniprot id: A0A2Y9I8R3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:SEMA6A
gene id: 29088:SEMA6A
uniprot id: A0A2Y9I7A3
uniprot id: A0A8M1MPD7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SMARCD3
gene id: 29088:SMARCD3
uniprot id: A0A8M1MQ05
names: Similarity
messages: Belongs to the SMARCD family.

29088:CCN5
gene id: 29088:CCN5
uniprot id: A0A2Y9H6C2
names: Similarity
messages: Belongs to the CCN family.

29088:OAS2
gene id: 29088:OAS2
uniprot id: A0A8M1MYV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-5A synthase family.
messages: Cytoplasm

29088:LOC110575272
gene id: 29088:LOC110575272
uniprot id: A0A8M1M1L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

29088:LOC110581597
gene id: 29088:LOC110581597
uniprot id: A0A2Y9H6A6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:PDS5A
gene id: 29088:PDS5A
uniprot id: A0A2Y9I4V9
names: Similarity
messages: Belongs to the PDS5 family.

29088:RPL27A
gene id: 29088:RPL27A
uniprot id: A0A2Y9GQ55
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

29088:NUMBL
gene id: 29088:NUMBL
uniprot id: A0A2Y9I339
uniprot id: A0A2Y9I4Y5
names: Function
messages: Plays a role in the process of neurogenesis.

29088:FOXP2
gene id: 29088:FOXP2
uniprot id: A0A2Y9HTI5
uniprot id: A0A2Y9HU18
uniprot id: A0A2Y9HU19
uniprot id: A0A2Y9HYX1
uniprot id: A0A8M1MQ86
uniprot id: A0A8M1MQ91
uniprot id: A0A8M1MQ95
uniprot id: A0A8M1MQ99
uniprot id: A0A8M1MS50
uniprot id: A0A8M1MS54
uniprot id: A0A8M1MTH9
uniprot id: A0A8M1MY92
uniprot id: A0A8M1MY93
names: Subcellular Location Annotation
messages: Nucleus

29088:DARS1
gene id: 29088:DARS1
uniprot id: A0A2Y9HI89
uniprot id: A0A2Y9HIN7
uniprot id: A0A2Y9HPC8
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

29088:TCP11
gene id: 29088:TCP11
uniprot id: A0A2Y9GQZ8
uniprot id: A0A8M1MHF7
uniprot id: A0A8M1MKU0
uniprot id: A0A8M1MRC7
names: Similarity
messages: Belongs to the TCP11 family.

29088:PCYOX1L
gene id: 29088:PCYOX1L
uniprot id: A0A2Y9HSB2
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

29088:TMEM184B
gene id: 29088:TMEM184B
uniprot id: A0A8M1MDX5
names: Subcellular Location Annotation
messages: Membrane

29088:MTFR2
gene id: 29088:MTFR2
uniprot id: A0A2Y9HBJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

29088:PRDM4
gene id: 29088:PRDM4
uniprot id: A0A2Y9GVQ7
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor involved in cell differentiation.
messages: Nucleus

29088:LOC110594205
gene id: 29088:LOC110594205
uniprot id: A0A8M1M054
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

29088:SETDB2
gene id: 29088:SETDB2
uniprot id: A0A8M1M6J9
uniprot id: A0A8M1M6U8
names: Subcellular Location Annotation
messages: Chromosome

29088:ENDOG
gene id: 29088:ENDOG
uniprot id: A0A2Y9HBP8
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

29088:LOC110591437
gene id: 29088:LOC110591437
uniprot id: A0A2Y9I2C4
names: Function
names: Subcellular Location Annotation
messages: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
messages: Secreted

29088:RNGTT
gene id: 29088:RNGTT
uniprot id: A0A2Y9HAT1
uniprot id: A0A8M1MH17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
messages: In the C-terminal section; belongs to the eukaryotic GTase family.
messages: In the N-terminal section; belongs to the non-receptor class of the protein-tyrosine phosphatase family.
messages: Nucleus

29088:CFAP126
gene id: 29088:CFAP126
uniprot id: A0A2Y9GEJ3
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the Flattop family.

29088:HHAT
gene id: 29088:HHAT
uniprot id: A0A8M1MEP6
names: Subcellular Location Annotation
messages: Membrane

29088:TRAPPC6B
gene id: 29088:TRAPPC6B
uniprot id: A0A2Y9HZ67
uniprot id: A0A2Y9HZD6
uniprot id: A0A2Y9HZL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

29088:ARHGEF1
gene id: 29088:ARHGEF1
uniprot id: A0A2Y9H8C6
uniprot id: A0A2Y9HDZ5
uniprot id: A0A2Y9HF22
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

29088:GPR83
gene id: 29088:GPR83
uniprot id: A0A2Y9G9B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

29088:DVL3
gene id: 29088:DVL3
uniprot id: A0A2Y9H954
uniprot id: A0A2Y9HFQ1
uniprot id: A0A8M1MQ77
uniprot id: A0A8M1MY91
names: Similarity
messages: Belongs to the DSH family.

29088:ADGRL2
gene id: 29088:ADGRL2
uniprot id: A0A2Y9H2M1
uniprot id: A0A2Y9H2N6
uniprot id: A0A2Y9H2Q3
uniprot id: A0A2Y9H9A5
uniprot id: A0A8M1M9E0
uniprot id: A0A8M1M9M0
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110577681
gene id: 29088:LOC110577681
uniprot id: A0A2Y9GU58
names: Similarity
messages: Belongs to the TPPP family.

29088:PIR
gene id: 29088:PIR
uniprot id: A0A2Y9GCJ0
names: Similarity
messages: Belongs to the pirin family.

29088:SLC39A3
gene id: 29088:SLC39A3
uniprot id: A0A2Y9IF72
names: Subcellular Location Annotation
messages: Membrane

29088:UBA1
gene id: 29088:UBA1
uniprot id: A0A8M1M214
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

29088:FLNC
gene id: 29088:FLNC
uniprot id: A0A2Y9HTK3
uniprot id: A0A2Y9HU40
uniprot id: A0A2Y9HU44
uniprot id: A0A2Y9HYZ4
uniprot id: A0A2Y9I0H9
names: Similarity
messages: Belongs to the filamin family.

29088:BANF2
gene id: 29088:BANF2
uniprot id: A0A2Y9HXK3
names: Subcellular Location Annotation
messages: Nucleus

29088:LZIC
gene id: 29088:LZIC
uniprot id: A0A2Y9GIV4
uniprot id: A0A2Y9GP49
names: Similarity
messages: Belongs to the CTNNBIP1 family.

29088:LOC110579961
gene id: 29088:LOC110579961
uniprot id: A0A2Y9H5V1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

29088:NEDD9
gene id: 29088:NEDD9
uniprot id: A0A2Y9HLQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

29088:LOC110569718
gene id: 29088:LOC110569718
uniprot id: A0A2Y9G6C0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

29088:SH3YL1
gene id: 29088:SH3YL1
uniprot id: A0A2Y9HTC4
uniprot id: A0A2Y9HUR7
names: Similarity
names: Subunit
messages: Belongs to the SH3YL1 family.
messages: Interacts with SH3D19.

29088:ARMC8
gene id: 29088:ARMC8
uniprot id: A0A2Y9G6B4
uniprot id: A0A8M1MFN2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:LOC110575557
gene id: 29088:LOC110575557
uniprot id: A0A2Y9GM04
names: Similarity
messages: Belongs to the MHC class II family.

29088:FOXN4
gene id: 29088:FOXN4
uniprot id: A0A2Y9I5M0
names: Subcellular Location Annotation
messages: Nucleus

29088:ARRDC1
gene id: 29088:ARRDC1
uniprot id: A0A2Y9H4X1
names: Similarity
messages: Belongs to the arrestin family.

29088:PES1
gene id: 29088:PES1
uniprot id: A0A2Y9ICJ3
uniprot id: A0A8M1MW23
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Chromosome
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome. Interacts with IRS1 and UBTF. May interact with MAP1B.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: Sumoylated.
messages: nucleolus
messages: nucleoplasm

29088:LOC110580189
gene id: 29088:LOC110580189
uniprot id: A0A8M1M5K5
names: Similarity
messages: Belongs to the SERF family.

29088:LOC110576215
gene id: 29088:LOC110576215
uniprot id: A0A8M1MNP8
names: Similarity
messages: Belongs to the actin family.

29088:UNC93A
gene id: 29088:UNC93A
uniprot id: A0A2Y9HB38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

29088:PRKCI
gene id: 29088:PRKCI
uniprot id: A0A2Y9I7N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

29088:RNF141
gene id: 29088:RNF141
uniprot id: A0A2Y9GQ75
names: Function
messages: May be involved in spermatogenesis.

29088:CRYGS
gene id: 29088:CRYGS
uniprot id: A0A2Y9H9P7
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

29088:NR2F1
gene id: 29088:NR2F1
uniprot id: A0A8M1MG21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

29088:PSMA1
gene id: 29088:PSMA1
uniprot id: A0A8M1M6H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

29088:ITGA6
gene id: 29088:ITGA6
uniprot id: A0A2Y9IB82
uniprot id: A0A8M1M6W6
uniprot id: A0A8M1M764
uniprot id: A0A8M1MAQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

29088:WEE2
gene id: 29088:WEE2
uniprot id: A0A8M1MQG2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

29088:PTH
gene id: 29088:PTH
uniprot id: A0A2Y9GUC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the parathyroid hormone family.
messages: Interacts with PTH1R (via N-terminal extracellular domain).
messages: PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
messages: Secreted

29088:RGS3
gene id: 29088:RGS3
uniprot id: A0A8M1MU16
uniprot id: A0A8M1MVE2
uniprot id: A0A8M1MYN6
names: Subcellular Location Annotation
messages: Cytoplasm

29088:CHST12
gene id: 29088:CHST12
uniprot id: A0A2Y9GA27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:LOC110591512
gene id: 29088:LOC110591512
uniprot id: A0A8M1M4B6
names: Similarity
messages: Belongs to the SAP18 family.

29088:HAO2
gene id: 29088:HAO2
uniprot id: A0A2Y9H9F0
uniprot id: A0A8M1MBY6
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

29088:ABHD2
gene id: 29088:ABHD2
uniprot id: A0A2Y9GBH3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

29088:EPHA2
gene id: 29088:EPHA2
uniprot id: A0A2Y9GQY5
names: Subcellular Location Annotation
messages: Membrane

29088:NPY1R
gene id: 29088:NPY1R
uniprot id: A0A2Y9HZ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:OPA3
gene id: 29088:OPA3
uniprot id: A0A2Y9GFN8
names: Function
names: Similarity
messages: Belongs to the OPA3 family.
messages: May play some role in mitochondrial processes.

29088:CLUL1
gene id: 29088:CLUL1
uniprot id: A0A2Y9GVH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Secreted

29088:DOCK11
gene id: 29088:DOCK11
uniprot id: A0A8M1M3Y7
uniprot id: A0A8M1M992
names: Similarity
messages: Belongs to the DOCK family.

29088:STAT1
gene id: 29088:STAT1
uniprot id: A0A2Y9I4D2
uniprot id: A0A8M1M779
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

29088:LOC123325301
gene id: 29088:LOC123325301
uniprot id: A0A8M1MK05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ATP8B3
gene id: 29088:ATP8B3
uniprot id: A0A2Y9IB89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

29088:PGM1
gene id: 29088:PGM1
uniprot id: A0A2Y9G9P8
uniprot id: A0A8M1MBR3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

29088:DSC3
gene id: 29088:DSC3
uniprot id: A0A2Y9GV61
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

29088:EXOC8
gene id: 29088:EXOC8
uniprot id: A0A2Y9HJ36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO84 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: growth cone
messages: perinuclear region

29088:TMEM132D
gene id: 29088:TMEM132D
uniprot id: A0A2Y9HRV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

29088:WASF3
gene id: 29088:WASF3
uniprot id: A0A2Y9G6Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

29088:UBXN1
gene id: 29088:UBXN1
uniprot id: A0A2Y9GN17
uniprot id: A0A2Y9GN97
names: Subcellular Location Annotation
messages: Cytoplasm

29088:LOC110587283
gene id: 29088:LOC110587283
uniprot id: A0A2Y9HNC8
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

29088:MFNG
gene id: 29088:MFNG
uniprot id: A0A2Y9H1L2
uniprot id: A0A8M1MF89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:LOC110581930
gene id: 29088:LOC110581930
uniprot id: A0A2Y9H774
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

29088:FTMT
gene id: 29088:FTMT
uniprot id: A0A2Y9I1A2
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:PLXNB2
gene id: 29088:PLXNB2
uniprot id: A0A8M1MBR5
uniprot id: A0A8M1MK50
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:DMAC2L
gene id: 29088:DMAC2L
uniprot id: A0A2Y9HZL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP synthase subunit s family.
messages: Homotetramer. Associates with ATP synthase.
messages: Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway.
messages: Membrane
messages: Mitochondrion inner membrane

29088:ZC3HAV1
gene id: 29088:ZC3HAV1
uniprot id: A0A8M1MPZ3
names: Similarity
messages: Belongs to the ARTD/PARP family.

29088:INHBE
gene id: 29088:INHBE
uniprot id: A0A2Y9H0G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

29088:ATP6V1F
gene id: 29088:ATP6V1F
uniprot id: A0A2Y9HYZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

29088:CTNNA2
gene id: 29088:CTNNA2
uniprot id: A0A8M1MMH4
uniprot id: A0A8M1MMH5
uniprot id: A0A8M1MPG4
uniprot id: A0A8M1MQS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: adherens junction
messages: axon
messages: cytoskeleton

29088:LOC110580904
gene id: 29088:LOC110580904
uniprot id: A0A8M1MAN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

29088:NSUN6
gene id: 29088:NSUN6
uniprot id: A0A2Y9HSM8
uniprot id: A0A8M1MED3
uniprot id: A0A8M1MJ67
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

29088:LOC110580768
gene id: 29088:LOC110580768
uniprot id: A0A8M1MBI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

29088:CIAO1
gene id: 29088:CIAO1
uniprot id: A0A2Y9HT63
uniprot id: A0A2Y9HUJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Component of the CIA complex. Component of the MMXD complex, which includes CIAO1, ERCC2, FAM96B, MMS19 and SLC25A5. Interacts with WT1. Interacts with FAM96A.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.

29088:ACTN3
gene id: 29088:ACTN3
uniprot id: A0A2Y9GNG5
names: Similarity
messages: Belongs to the alpha-actinin family.

29088:LOC110594269
gene id: 29088:LOC110594269
uniprot id: A0A2Y9ICQ7
uniprot id: A0A8M1M0J8
uniprot id: A0A8M1M0V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL2BP family.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Nucleus
messages: Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
messages: centrosome
messages: cilium basal body

29088:KIF1C
gene id: 29088:KIF1C
uniprot id: A0A2Y9HFK5
uniprot id: A0A2Y9HFZ5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:LTF
gene id: 29088:LTF
uniprot id: A0A2Y9GHT6
uniprot id: A0A2Y9GHW0
names: Similarity
messages: Belongs to the transferrin family.

29088:PTCH2
gene id: 29088:PTCH2
uniprot id: A0A2Y9GK06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

29088:GDAP2
gene id: 29088:GDAP2
uniprot id: A0A2Y9H2A0
names: Similarity
messages: Belongs to the GDAP2 family.

29088:LOC110573813
gene id: 29088:LOC110573813
uniprot id: A0A8M1MVD8
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

29088:SPO11
gene id: 29088:SPO11
uniprot id: A0A2Y9G332
uniprot id: A0A8M1MVA1
names: Similarity
messages: Belongs to the TOP6A family.

29088:LOC110570256
gene id: 29088:LOC110570256
uniprot id: A0A2Y9G4F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

29088:CX3CL1
gene id: 29088:CX3CL1
uniprot id: A0A2Y9ICR1
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

29088:CCNC
gene id: 29088:CCNC
uniprot id: A0A2Y9HGW3
uniprot id: A0A8M1MHD7
uniprot id: A0A8M1MHE3
uniprot id: A0A8M1MJG8
uniprot id: A0A8M1MKS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.
messages: Nucleus

29088:B3GNT7
gene id: 29088:B3GNT7
uniprot id: A0A2Y9H331
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:ADGRB1
gene id: 29088:ADGRB1
uniprot id: A0A8M1MH33
names: Subcellular Location Annotation
messages: Membrane

29088:SAXO1
gene id: 29088:SAXO1
uniprot id: A0A2Y9GG67
names: Similarity
messages: Belongs to the FAM154 family.

29088:LOC110591015
gene id: 29088:LOC110591015
uniprot id: A0A2Y9GT67
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:PDCL3
gene id: 29088:PDCL3
uniprot id: A0A2Y9GAD3
names: Similarity
messages: Belongs to the phosducin family.

29088:DUSP13
gene id: 29088:DUSP13
uniprot id: A0A2Y9HW34
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

29088:LOC110583961
gene id: 29088:LOC110583961
uniprot id: A0A2Y9HJP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

29088:LOC110582778
gene id: 29088:LOC110582778
uniprot id: A0A2Y9H9Q9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:DNAJC27
gene id: 29088:DNAJC27
uniprot id: A0A2Y9HVA9
names: Function
names: Subunit
messages: GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.
messages: Interacts directly with MAPK1 (wild-type and kinase-deficient forms). Interacts directly (in GTP-bound form) with MAP2K1 (wild-type and kinase-deficient forms).

29088:LOC110569898
gene id: 29088:LOC110569898
uniprot id: A0A2Y9HM51
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

29088:CSNK2A2
gene id: 29088:CSNK2A2
uniprot id: A0A8M1MX90
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:LOC110588821
gene id: 29088:LOC110588821
uniprot id: A0A8M1MQ04
uniprot id: A0A8M1MVX1
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

29088:IRAK1BP1
gene id: 29088:IRAK1BP1
uniprot id: A0A2Y9HHT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

29088:LOC110586648
gene id: 29088:LOC110586648
uniprot id: A0A2Y9HLH7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:TMEM98
gene id: 29088:TMEM98
uniprot id: A0A2Y9IC70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM98 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: extracellular exosome

29088:HTRA3
gene id: 29088:HTRA3
uniprot id: A0A2Y9G399
names: Similarity
messages: Belongs to the peptidase S1C family.

29088:HBM
gene id: 29088:HBM
uniprot id: A0A2Y9HQR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the globin family.
messages: Heterotetramer of two alpha chains and two beta chains.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.

29088:LOC110593040
gene id: 29088:LOC110593040
uniprot id: A0A2Y9I8D4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

29088:FAM20A
gene id: 29088:FAM20A
uniprot id: A0A2Y9G505
uniprot id: A0A8M1MVF0
names: Similarity
messages: Belongs to the FAM20 family.

29088:LYZL4
gene id: 29088:LYZL4
uniprot id: A0A2Y9G679
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

29088:STOM
gene id: 29088:STOM
uniprot id: A0A2Y9H783
uniprot id: A0A2Y9HDX0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

29088:CD63
gene id: 29088:CD63
uniprot id: A0A2Y9H056
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Cell surface
messages: Endosome membrane
messages: Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.
messages: Late endosome membrane
messages: Lysosome membrane
messages: Melanosome
messages: Membrane
messages: extracellular exosome
messages: multivesicular body

29088:LOC110585006
gene id: 29088:LOC110585006
uniprot id: A0A8M1MG90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

29088:LAMC2
gene id: 29088:LAMC2
uniprot id: A0A2Y9GH51
uniprot id: A0A2Y9GH57
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

29088:CCNQ
gene id: 29088:CCNQ
uniprot id: A0A2Y9GHR8
uniprot id: A0A2Y9GHT1
uniprot id: A0A2Y9GHT8
uniprot id: A0A2Y9GMW5
names: Similarity
messages: Belongs to the cyclin family. Cyclin-like FAM58 subfamily.

29088:ESX1
gene id: 29088:ESX1
uniprot id: A0A2Y9G577
names: Subcellular Location Annotation
messages: Nucleus

29088:STX6
gene id: 29088:STX6
uniprot id: A0A2Y9GLH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Golgi apparatus membrane

29088:RSRP1
gene id: 29088:RSRP1
uniprot id: A0A2Y9GJA0
names: Similarity
messages: Belongs to the RSRP family.

29088:SPC25
gene id: 29088:SPC25
uniprot id: A0A2Y9I4Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

29088:PRKCE
gene id: 29088:PRKCE
uniprot id: A0A2Y9HYS6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin-dependent signaling, by mediating angiotensin-2-induced activation of integrin beta-1 (ITGB1) in cardiac fibroblasts. Phosphorylates MARCKS, which phosphorylates and activates PTK2/FAK, leading to the spread of cardiomyocytes. Involved in the control of the directional transport of ITGB1 in mesenchymal cells by phosphorylating vimentin (VIM), an intermediate filament (IF) protein. In epithelial cells, associates with and phosphorylates keratin-8 (KRT8), which induces targeting of desmoplakin at desmosomes and regulates cell-cell contact. Phosphorylates IQGAP1, which binds to CDC42, mediating epithelial cell-cell detachment prior to migration.
messages: Cell membrane
messages: Cytoplasm
messages: Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine.
messages: Nucleus
messages: cytoskeleton
messages: perinuclear region

29088:GABRA5
gene id: 29088:GABRA5
uniprot id: A0A2Y9GB06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:PTGDR2
gene id: 29088:PTGDR2
uniprot id: A0A8M1MNS3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:ATP6V1G1
gene id: 29088:ATP6V1G1
uniprot id: A0A2Y9H788
uniprot id: A0A8M1MYQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

29088:THY1
gene id: 29088:THY1
uniprot id: A0A2Y9HK15
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
messages: Membrane

29088:ST3GAL5
gene id: 29088:ST3GAL5
uniprot id: A0A2Y9HMS7
uniprot id: A0A8M1MMJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

29088:DUOXA2
gene id: 29088:DUOXA2
uniprot id: A0A2Y9HH26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

29088:CRYGN
gene id: 29088:CRYGN
uniprot id: A0A2Y9HA69
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

29088:SLC35A3
gene id: 29088:SLC35A3
uniprot id: A0A2Y9H9N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

29088:INTS13
gene id: 29088:INTS13
uniprot id: A0A8M1MCR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the asunder family.
messages: Cytoplasm
messages: Nucleus

29088:SCRN3
gene id: 29088:SCRN3
uniprot id: A0A2Y9I4D7
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

29088:CERCAM
gene id: 29088:CERCAM
uniprot id: A0A2Y9HBH3
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

29088:HOXB3
gene id: 29088:HOXB3
uniprot id: A0A2Y9I6W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

29088:LOC110592253
gene id: 29088:LOC110592253
uniprot id: A0A8M1MAS0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

29088:LOC110582985
gene id: 29088:LOC110582985
uniprot id: A0A8M1M1E4
names: Similarity
messages: Belongs to the SCC3 family.

29088:CLN3
gene id: 29088:CLN3
uniprot id: A0A2Y9HWR8
uniprot id: A0A2Y9HWZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Lysosome membrane
messages: Membrane

29088:FOXO4
gene id: 29088:FOXO4
uniprot id: A0A2Y9GAQ3
uniprot id: A0A8M1M1B5
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110577355
gene id: 29088:LOC110577355
uniprot id: A0A8M1M1B0
names: Similarity
messages: Belongs to the IAP family.

29088:NKX2-4
gene id: 29088:NKX2-4
uniprot id: A0A2Y9I4C1
names: Subcellular Location Annotation
messages: Nucleus

29088:SLC35F4
gene id: 29088:SLC35F4
uniprot id: A0A2Y9I6G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

29088:PCSK2
gene id: 29088:PCSK2
uniprot id: A0A8M1MLA4
uniprot id: A0A8M1MPK8
names: Similarity
messages: Belongs to the peptidase S8 family.

29088:LOC110573779
gene id: 29088:LOC110573779
uniprot id: A0A8M1MVA8
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

29088:LOC110569921
gene id: 29088:LOC110569921
uniprot id: A0A8M1MS31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

29088:LPXN
gene id: 29088:LPXN
uniprot id: A0A2Y9GN30
names: Similarity
messages: Belongs to the paxillin family.

29088:DPPA2
gene id: 29088:DPPA2
uniprot id: A0A2Y9H9M5
names: Subcellular Location Annotation
messages: Nucleus

29088:LAMTOR4
gene id: 29088:LAMTOR4
uniprot id: A0A2Y9G9W4
uniprot id: A0A8M1MB56
uniprot id: A0A8M1MDG0
uniprot id: A0A8M1MJP0
names: Similarity
messages: Belongs to the LAMTOR4 family.

29088:SLC35B2
gene id: 29088:SLC35B2
uniprot id: A0A2Y9HCV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

29088:NIBAN1
gene id: 29088:NIBAN1
uniprot id: A0A2Y9GH64
names: Similarity
messages: Belongs to the Niban family.

29088:SLC18B1
gene id: 29088:SLC18B1
uniprot id: A0A2Y9HB36
names: Subcellular Location Annotation
messages: Membrane

29088:XRCC4
gene id: 29088:XRCC4
uniprot id: A0A8M1MFU4
uniprot id: A0A8M1MJA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XRCC4 subfamily.
messages: Nucleus

29088:HMX2
gene id: 29088:HMX2
uniprot id: A0A2Y9I6P4
names: Subcellular Location Annotation
messages: Nucleus

29088:BBS2
gene id: 29088:BBS2
uniprot id: A0A2Y9IGB6
names: Subcellular Location Annotation
messages: centriolar satellite
messages: cilium membrane

29088:HS6ST3
gene id: 29088:HS6ST3
uniprot id: A0A2Y9HPV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

29088:XPA
gene id: 29088:XPA
uniprot id: A0A2Y9H6V2
uniprot id: A0A8M1MTZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

29088:LOC110577710
gene id: 29088:LOC110577710
uniprot id: A0A2Y9GYC9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:CRBN
gene id: 29088:CRBN
uniprot id: A0A2Y9HG53
uniprot id: A0A2Y9HGD9
uniprot id: A0A2Y9HMG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRBN family.
messages: Nucleus

29088:CPE
gene id: 29088:CPE
uniprot id: A0A2Y9HYQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M14 family.
messages: Interacts with Secretogranin III/SCG3.
messages: Membrane
messages: Sorting receptor that directs prohormones to the regulated secretory pathway. Acts also as a prohormone processing enzyme in neuro/endocrine cells, removing dibasic residues from the C-terminal end of peptide hormone precursors after initial endoprotease cleavage.
messages: secretory vesicle membrane

29088:SPTBN1
gene id: 29088:SPTBN1
uniprot id: A0A2Y9I5G3
uniprot id: A0A8M1ML01
names: Similarity
messages: Belongs to the spectrin family.

29088:FHIP2A
gene id: 29088:FHIP2A
uniprot id: A0A2Y9I1S5
names: Similarity
messages: Belongs to the FHIP family.

29088:LOC110576552
gene id: 29088:LOC110576552
uniprot id: A0A2Y9GU71
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:CDK9
gene id: 29088:CDK9
uniprot id: A0A2Y9HB82
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:SLC30A2
gene id: 29088:SLC30A2
uniprot id: A0A2Y9GJA1
uniprot id: A0A2Y9GPJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

29088:NOB1
gene id: 29088:NOB1
uniprot id: A0A2Y9I4S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: May play a role in mRNA degradation.
messages: Nucleus

29088:GPR137
gene id: 29088:GPR137
uniprot id: A0A2Y9GN31
uniprot id: A0A2Y9GNE9
uniprot id: A0A8M1MMQ0
uniprot id: A0A8M1MMQ1
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

29088:LOC123323420
gene id: 29088:LOC123323420
uniprot id: A0A8M1M261
names: Subcellular Location Annotation
messages: Nucleus

29088:PAQR5
gene id: 29088:PAQR5
uniprot id: A0A2Y9HCF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

29088:ORMDL1
gene id: 29088:ORMDL1
uniprot id: A0A2Y9I430
uniprot id: A0A2Y9IAP7
uniprot id: A0A8M1M9U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

29088:LOC110583791
gene id: 29088:LOC110583791
uniprot id: A0A2Y9HCJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

29088:PTK7
gene id: 29088:PTK7
uniprot id: A0A2Y9H7Z0
names: Subcellular Location Annotation
messages: Membrane

29088:CXCL11
gene id: 29088:CXCL11
uniprot id: A0A2Y9I774
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

29088:PTX4
gene id: 29088:PTX4
uniprot id: A0A2Y9HPJ5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:BLM
gene id: 29088:BLM
uniprot id: A0A8M1MK72
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

29088:ATRX
gene id: 29088:ATRX
uniprot id: A0A2Y9G6G3
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

29088:PPEF1
gene id: 29088:PPEF1
uniprot id: A0A2Y9GNR9
names: Similarity
messages: Belongs to the PPP phosphatase family.

29088:ST3GAL2
gene id: 29088:ST3GAL2
uniprot id: A0A2Y9IBF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

29088:SLC25A14
gene id: 29088:SLC25A14
uniprot id: A0A2Y9GQ11
uniprot id: A0A8M1M596
uniprot id: A0A8M1M908
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:SLC5A5
gene id: 29088:SLC5A5
uniprot id: A0A2Y9GI05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

29088:YES1
gene id: 29088:YES1
uniprot id: A0A2Y9GWR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

29088:VEGFA
gene id: 29088:VEGFA
uniprot id: A0A8M1MKF2
uniprot id: A0A8M1MLQ9
uniprot id: A0A8M1MSB9
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

29088:LOC110583537
gene id: 29088:LOC110583537
uniprot id: A0A8M1MH27
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

29088:TAF7L
gene id: 29088:TAF7L
uniprot id: A0A2Y9HI20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

29088:FAM241A
gene id: 29088:FAM241A
uniprot id: A0A2Y9GM23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM241 family.
messages: Membrane

29088:LOC110589685
gene id: 29088:LOC110589685
uniprot id: A0A8M1MIM7
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

29088:CES1
gene id: 29088:CES1
uniprot id: A0A2Y9I8Q3
uniprot id: A0A2Y9IFV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

29088:LOC110570205
gene id: 29088:LOC110570205
uniprot id: A0A2Y9G4A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

29088:CKS2
gene id: 29088:CKS2
uniprot id: A0A2Y9GRF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

29088:NOP2
gene id: 29088:NOP2
uniprot id: A0A2Y9H3I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: nucleolus

29088:LOC110571275
gene id: 29088:LOC110571275
uniprot id: A0A2Y9G7U4
names: Function
names: Similarity
messages: Belongs to the SSX family.
messages: Could act as a modulator of transcription.

29088:FADS2
gene id: 29088:FADS2
uniprot id: A0A2Y9GPL9
uniprot id: A0A2Y9GTG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Endoplasmic reticulum membrane

29088:LOC110590831
gene id: 29088:LOC110590831
uniprot id: A0A8M1M841
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Nucleus

29088:GLP1R
gene id: 29088:GLP1R
uniprot id: A0A2Y9GR21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

29088:SPIRE1
gene id: 29088:SPIRE1
uniprot id: A0A2Y9GHQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

29088:LOC110585770
gene id: 29088:LOC110585770
uniprot id: A0A8M1MIJ3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

29088:CERS2
gene id: 29088:CERS2
uniprot id: A0A2Y9H192
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

29088:YIPF3
gene id: 29088:YIPF3
uniprot id: A0A2Y9H868
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis.
messages: Membrane
messages: cis-Golgi network membrane

29088:SIGMAR1
gene id: 29088:SIGMAR1
uniprot id: A0A2Y9H604
uniprot id: A0A2Y9HBD7
uniprot id: A0A2Y9HCQ6
uniprot id: A0A8M1MRG8
uniprot id: A0A8M1MTC8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERG2 family.
messages: Cell junction
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum membrane
messages: Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the endoplasmic reticulum.
messages: Homotrimer.
messages: Lipid droplet
messages: Membrane
messages: Nucleus envelope
messages: Nucleus inner membrane
messages: Nucleus outer membrane
messages: Postsynaptic density membrane
messages: The C-terminal helices form a flat, hydrophobic surface that is probably tightly associated with the cytosolic surface of the endoplasmic reticulum membrane.
messages: Vesicle

29088:MMAB
gene id: 29088:MMAB
uniprot id: A0A2Y9I662
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

29088:ATP7A
gene id: 29088:ATP7A
uniprot id: A0A2Y9G6D8
uniprot id: A0A8M1M4U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

29088:IL1F10
gene id: 29088:IL1F10
uniprot id: A0A2Y9HP62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

29088:LOC110588169
gene id: 29088:LOC110588169
uniprot id: A0A8M1MDT5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

29088:AVPR1B
gene id: 29088:AVPR1B
uniprot id: A0A2Y9GWT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

29088:CDK5R2
gene id: 29088:CDK5R2
uniprot id: A0A2Y9I5C1
names: Similarity
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Heterodimer of a catalytic subunit and a regulatory subunit.

29088:SLC48A1
gene id: 29088:SLC48A1
uniprot id: A0A2Y9IGM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRG family.
messages: Endosome membrane
messages: Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment.
messages: Lysosome membrane
messages: Membrane

29088:TMEM54
gene id: 29088:TMEM54
uniprot id: A0A8M1M7P6
uniprot id: A0A8M1M7Y3
uniprot id: A0A8M1MA41
uniprot id: A0A8M1MBH0
uniprot id: A0A8M1MG03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

29088:RAB39A
gene id: 29088:RAB39A
uniprot id: A0A2Y9HRY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

29088:MICOS10
gene id: 29088:MICOS10
uniprot id: A0A2Y9GMP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

29088:SUZ12
gene id: 29088:SUZ12
uniprot id: A0A2Y9I951
uniprot id: A0A8M1MXT6
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

29088:SART1
gene id: 29088:SART1
uniprot id: A0A2Y9GNA1
uniprot id: A0A2Y9GU15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

29088:WASHC1
gene id: 29088:WASHC1
uniprot id: A0A2Y9H4C6
uniprot id: A0A2Y9H4E4
uniprot id: A0A8M1MC96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WASH1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Recycling endosome membrane

29088:ATP6V0D2
gene id: 29088:ATP6V0D2
uniprot id: A0A2Y9H3N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

29088:UBE3D
gene id: 29088:UBE3D
uniprot id: A0A2Y9HAU9
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

29088:LOC110592001
gene id: 29088:LOC110592001
uniprot id: A0A8M1M964
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

29088:FGFR1OP2
gene id: 29088:FGFR1OP2
uniprot id: A0A2Y9H3F4
uniprot id: A0A2Y9H8I9
uniprot id: A0A2Y9HA43
uniprot id: A0A8M1MIX5
names: Similarity
messages: Belongs to the SIKE family.

29088:LOC110585369
gene id: 29088:LOC110585369
uniprot id: A0A8M1MN52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MFSD9
gene id: 29088:MFSD9
uniprot id: A0A2Y9GE87
names: Subcellular Location Annotation
messages: Membrane

29088:SLC44A2
gene id: 29088:SLC44A2
uniprot id: A0A2Y9IBB8
uniprot id: A0A2Y9IBC2
uniprot id: A0A2Y9IC57
uniprot id: A0A2Y9IFS7
uniprot id: A0A2Y9IIU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

29088:MTHFR
gene id: 29088:MTHFR
uniprot id: A0A2Y9GJ70
uniprot id: A0A8M1M9W4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

29088:PLAA
gene id: 29088:PLAA
uniprot id: A0A2Y9GCC8
uniprot id: A0A2Y9GFA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PLAP family.
messages: Cytoplasm

29088:SEMA6C
gene id: 29088:SEMA6C
uniprot id: A0A2Y9GWK2
uniprot id: A0A2Y9GWX9
uniprot id: A0A2Y9H0Y6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:DYRK2
gene id: 29088:DYRK2
uniprot id: A0A2Y9G5P6
uniprot id: A0A2Y9G643
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

29088:LOC110587742
gene id: 29088:LOC110587742
uniprot id: A0A8M1M5G0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

29088:ATRAID
gene id: 29088:ATRAID
uniprot id: A0A2Y9HTK1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:NSUN2
gene id: 29088:NSUN2
uniprot id: A0A8M1MGG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: extracellular exosome

29088:STAM2
gene id: 29088:STAM2
uniprot id: A0A2Y9IA51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

29088:PPM1B
gene id: 29088:PPM1B
uniprot id: A0A2Y9HZ34
uniprot id: A0A2Y9I5H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

29088:ERCC2
gene id: 29088:ERCC2
uniprot id: A0A8M1M0E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

29088:RABEP1
gene id: 29088:RABEP1
uniprot id: A0A2Y9HES8
uniprot id: A0A2Y9HEU0
uniprot id: A0A2Y9HF62
uniprot id: A0A2Y9HL37
uniprot id: A0A2Y9HL42
uniprot id: A0A2Y9HL83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Cytoplasm
messages: Early endosome
messages: Endosome

29088:VENTX
gene id: 29088:VENTX
uniprot id: A0A2Y9I6M9
names: Subcellular Location Annotation
messages: Nucleus

29088:C1QA
gene id: 29088:C1QA
uniprot id: A0A2Y9GJ66
names: Function
messages: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

29088:NAP1L5
gene id: 29088:NAP1L5
uniprot id: A0A2Y9I2I7
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

29088:GPR50
gene id: 29088:GPR50
uniprot id: A0A2Y9GIY8
uniprot id: A0A2Y9GJ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:LOC110594039
gene id: 29088:LOC110594039
uniprot id: A0A8M1MJQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:INHBB
gene id: 29088:INHBB
uniprot id: A0A2Y9HPD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

29088:SHBG
gene id: 29088:SHBG
uniprot id: A0A2Y9HF80
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:PEX7
gene id: 29088:PEX7
uniprot id: A0A2Y9HAX7
uniprot id: A0A2Y9HB75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Cytoplasm

29088:SCAMP3
gene id: 29088:SCAMP3
uniprot id: A0A2Y9GF09
uniprot id: A0A8M1MHV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

29088:LOC110571558
gene id: 29088:LOC110571558
uniprot id: A0A2Y9G8V2
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:BCR
gene id: 29088:BCR
uniprot id: A0A2Y9GW33
uniprot id: A0A2Y9GWB8
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

29088:ESRRG
gene id: 29088:ESRRG
uniprot id: A0A2Y9HR50
uniprot id: A0A2Y9HR75
uniprot id: A0A2Y9HW13
uniprot id: A0A2Y9HXL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

29088:ARV1
gene id: 29088:ARV1
uniprot id: A0A2Y9HQV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane

29088:ITGA4
gene id: 29088:ITGA4
uniprot id: A0A2Y9I8S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

29088:PANX3
gene id: 29088:PANX3
uniprot id: A0A2Y9HKM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

29088:PDE3B
gene id: 29088:PDE3B
uniprot id: A0A2Y9GQ85
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

29088:TRPT1
gene id: 29088:TRPT1
uniprot id: A0A2Y9GN15
uniprot id: A0A2Y9GS49
uniprot id: A0A2Y9GTS9
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

29088:UTRN
gene id: 29088:UTRN
uniprot id: A0A8M1MH19
uniprot id: A0A8M1MH22
uniprot id: A0A8M1MJ48
names: Subcellular Location Annotation
messages: cytoskeleton

29088:LOC110591694
gene id: 29088:LOC110591694
uniprot id: A0A8M1M4P6
names: Subcellular Location Annotation
messages: Nucleus

29088:ITM2C
gene id: 29088:ITM2C
uniprot id: A0A2Y9H313
uniprot id: A0A2Y9H9P1
uniprot id: A0A8M1M687
uniprot id: A0A8M1M8N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

29088:PLPPR5
gene id: 29088:PLPPR5
uniprot id: A0A2Y9H2Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

29088:DBR1
gene id: 29088:DBR1
uniprot id: A0A2Y9G9I6
uniprot id: A0A8M1MEA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

29088:HGD
gene id: 29088:HGD
uniprot id: A0A2Y9H8X1
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

29088:PEX1
gene id: 29088:PEX1
uniprot id: A0A8M1MPS7
uniprot id: A0A8M1MRN6
uniprot id: A0A8M1MY30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

29088:CD40LG
gene id: 29088:CD40LG
uniprot id: A0A2Y9GR88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
messages: Belongs to the tumor necrosis factor family.
messages: Cell surface
messages: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
messages: Homotrimer.

29088:GPR179
gene id: 29088:GPR179
uniprot id: A0A2Y9ICU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

29088:HTR5A
gene id: 29088:HTR5A
uniprot id: A0A2Y9HH18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:TEX13B
gene id: 29088:TEX13B
uniprot id: A0A2Y9G527
names: Similarity
messages: Belongs to the TEX13 family.

29088:IDO2
gene id: 29088:IDO2
uniprot id: A0A2Y9GDT3
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

29088:DPH5
gene id: 29088:DPH5
uniprot id: A0A2Y9H8Y1
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

29088:GPRIN1
gene id: 29088:GPRIN1
uniprot id: A0A8M1MPA2
names: Function
messages: May be involved in neurite outgrowth.

29088:NCAPH
gene id: 29088:NCAPH
uniprot id: A0A2Y9HUZ6
uniprot id: A0A8M1MLC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

29088:LOC110576476
gene id: 29088:LOC110576476
uniprot id: A0A2Y9GQ45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:FNIP2
gene id: 29088:FNIP2
uniprot id: A0A2Y9HSY5
uniprot id: A0A2Y9HSZ3
uniprot id: A0A8M1M705
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

29088:ZKSCAN5
gene id: 29088:ZKSCAN5
uniprot id: A0A2Y9GCU4
names: Subcellular Location Annotation
messages: Nucleus

29088:MSRB2
gene id: 29088:MSRB2
uniprot id: A0A2Y9HL96
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

29088:SERPIND1
gene id: 29088:SERPIND1
uniprot id: A0A2Y9GW53
names: Similarity
messages: Belongs to the serpin family.

29088:PIK3CD
gene id: 29088:PIK3CD
uniprot id: A0A2Y9GKH9
uniprot id: A0A2Y9GKL2
uniprot id: A0A2Y9GKS1
uniprot id: A0A2Y9GP77
uniprot id: A0A2Y9GQU8
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

29088:SIKE1
gene id: 29088:SIKE1
uniprot id: A0A2Y9H294
uniprot id: A0A8M1M8D6
names: Similarity
messages: Belongs to the SIKE family.

29088:BRD1
gene id: 29088:BRD1
uniprot id: A0A2Y9GV20
uniprot id: A0A2Y9GV81
uniprot id: A0A2Y9GVC4
uniprot id: A0A2Y9GZB0
uniprot id: A0A2Y9H136
uniprot id: A0A8M1MBL6
uniprot id: A0A8M1MBS0
uniprot id: A0A8M1MDV4
names: Subcellular Location Annotation
messages: Nucleus

29088:AKAP12
gene id: 29088:AKAP12
uniprot id: A0A2Y9HB20
names: Subcellular Location Annotation
messages: Membrane

29088:SVEP1
gene id: 29088:SVEP1
uniprot id: A0A2Y9H598
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:CELSR3
gene id: 29088:CELSR3
uniprot id: A0A2Y9GTK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

29088:SLC1A3
gene id: 29088:SLC1A3
uniprot id: A0A2Y9HJT9
uniprot id: A0A8M1MGC1
uniprot id: A0A8M1MGC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

29088:RPL7A
gene id: 29088:RPL7A
uniprot id: A0A2Y9H6M1
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

29088:DDX49
gene id: 29088:DDX49
uniprot id: A0A2Y9GLD0
names: Similarity
messages: Belongs to the DEAD box helicase family.

29088:ACTL7A
gene id: 29088:ACTL7A
uniprot id: A0A2Y9H730
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Golgi apparatus
messages: May play an important role in formation and fusion of Golgi-derived vesicles during acrosome biogenesis.
messages: Nucleus
messages: cytoskeleton

29088:APOD
gene id: 29088:APOD
uniprot id: A0A2Y9H8N7
uniprot id: A0A8M1M960
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Homodimer.
messages: Secreted

29088:KIF16B
gene id: 29088:KIF16B
uniprot id: A0A2Y9HXE6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:CEBPE
gene id: 29088:CEBPE
uniprot id: A0A2Y9HP79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

29088:ANXA3
gene id: 29088:ANXA3
uniprot id: A0A2Y9I902
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

29088:LOC110584133
gene id: 29088:LOC110584133
uniprot id: A0A2Y9HDY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: phagosome membrane

29088:LOC110577486
gene id: 29088:LOC110577486
uniprot id: A0A2Y9GT95
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SLAIN1
gene id: 29088:SLAIN1
uniprot id: A0A8M1M8Q5
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

29088:PSMB10
gene id: 29088:PSMB10
uniprot id: A0A2Y9I5F1
uniprot id: A0A2Y9IA92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

29088:MINDY1
gene id: 29088:MINDY1
uniprot id: A0A2Y9GWL0
uniprot id: A0A2Y9GWW3
uniprot id: A0A2Y9H0Z8
uniprot id: A0A8M1M9L2
uniprot id: A0A8M1M9U2
uniprot id: A0A8M1MBY7
uniprot id: A0A8M1MDB6
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

29088:PDCL
gene id: 29088:PDCL
uniprot id: A0A2Y9H696
names: Similarity
messages: Belongs to the phosducin family.

29088:TMEM132C
gene id: 29088:TMEM132C
uniprot id: A0A2Y9HRL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

29088:TNMD
gene id: 29088:TNMD
uniprot id: A0A2Y9HFL0
names: Similarity
messages: Belongs to the chondromodulin-1 family.

29088:USP16
gene id: 29088:USP16
uniprot id: A0A2Y9G3T1
uniprot id: A0A2Y9G4C8
uniprot id: A0A2Y9G6C3
uniprot id: A0A2Y9G6C8
uniprot id: A0A2Y9G7H1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. USP16 subfamily.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Homotetramer.
messages: Nucleus
messages: Phosphorylated at the onset of mitosis and dephosphorylated during the metaphase/anaphase transition. Phosphorylation by AURKB enhances the deubiquitinase activity.
messages: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.
messages: The UBP-type zinc finger binds 3 zinc ions that form a pair of cross-braced ring fingers encapsulated within a third zinc finger in the primary structure. It recognizes the C-terminal tail of free ubiquitin.

29088:SPEM1
gene id: 29088:SPEM1
uniprot id: A0A2Y9HF25
names: Subcellular Location Annotation
messages: Membrane

29088:ATG9A
gene id: 29088:ATG9A
uniprot id: A0A2Y9I3N1
uniprot id: A0A8M1M6F8
uniprot id: A0A8M1MA00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

29088:TADA2B
gene id: 29088:TADA2B
uniprot id: A0A2Y9G2I3
names: Subcellular Location Annotation
messages: Nucleus

29088:NDUFB4
gene id: 29088:NDUFB4
uniprot id: A0A2Y9H9C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB4 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:LITAFD
gene id: 29088:LITAFD
uniprot id: A0A8M1MEK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane
messages: Membrane

29088:NR2C2
gene id: 29088:NR2C2
uniprot id: A0A2Y9HM32
uniprot id: A0A8M1MEE5
uniprot id: A0A8M1MN58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

29088:SLC12A4
gene id: 29088:SLC12A4
uniprot id: A0A2Y9IG48
uniprot id: A0A2Y9IJ84
uniprot id: A0A8M1MWI1
uniprot id: A0A8M1MWI7
uniprot id: A0A8M1MXN1
uniprot id: A0A8M1MY70
uniprot id: A0A8M1MY72
uniprot id: A0A8M1MZJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

29088:WNT3
gene id: 29088:WNT3
uniprot id: A0A2Y9G560
uniprot id: A0A2Y9G7N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

29088:LOC110589943
gene id: 29088:LOC110589943
uniprot id: A0A2Y9I285
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.

29088:LOC110588597
gene id: 29088:LOC110588597
uniprot id: A0A8M1M7P7
names: Similarity
messages: Belongs to the NAC-beta family.

29088:ATAD2
gene id: 29088:ATAD2
uniprot id: A0A8M1M9P9
names: Similarity
messages: Belongs to the AAA ATPase family.

29088:GTF2A1
gene id: 29088:GTF2A1
uniprot id: A0A2Y9G8I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

29088:FGF2
gene id: 29088:FGF2
uniprot id: A0A8M1MDB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Nucleus
messages: Secreted

29088:LOC110585458
gene id: 29088:LOC110585458
uniprot id: A0A8M1MNJ6
names: Similarity
messages: Belongs to the TMA7 family.

29088:SMC4
gene id: 29088:SMC4
uniprot id: A0A2Y9I7W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC4 subfamily.
messages: Chromosome
messages: Nucleus

29088:LMF1
gene id: 29088:LMF1
uniprot id: A0A2Y9HQ71
uniprot id: A0A8M1MAU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Membrane

29088:BDH1
gene id: 29088:BDH1
uniprot id: A0A2Y9HFG5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:LOC110584967
gene id: 29088:LOC110584967
uniprot id: A0A2Y9HMW2
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

29088:CNOT7
gene id: 29088:CNOT7
uniprot id: A0A2Y9HE19
uniprot id: A0A8M1M1W1
uniprot id: A0A8M1M438
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

29088:LNPK
gene id: 29088:LNPK
uniprot id: A0A2Y9I5R4
uniprot id: A0A2Y9ICC1
uniprot id: A0A8M1M5X7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

29088:PRPH
gene id: 29088:PRPH
uniprot id: A0A2Y9I9B9
uniprot id: A0A8M1MCL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: axon

29088:KCNQ1
gene id: 29088:KCNQ1
uniprot id: A0A8M1MXJ6
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum
messages: Lateral cell membrane
messages: Membrane
messages: Membrane raft

29088:CLTA
gene id: 29088:CLTA
uniprot id: A0A2Y9H568
uniprot id: A0A8M1MSC4
uniprot id: A0A8M1MSC8
uniprot id: A0A8M1MSC9
uniprot id: A0A8M1MU74
uniprot id: A0A8M1MU79
uniprot id: A0A8M1MVJ9
uniprot id: A0A8M1MVK4
uniprot id: A0A8M1MYP8
uniprot id: A0A8M1MYP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

29088:TMEM131
gene id: 29088:TMEM131
uniprot id: A0A2Y9HZI0
uniprot id: A0A2Y9I411
uniprot id: A0A2Y9I5W7
names: Similarity
messages: Belongs to the TMEM131 family.

29088:NXT1
gene id: 29088:NXT1
uniprot id: A0A2Y9HXU7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

29088:CDV3
gene id: 29088:CDV3
uniprot id: A0A8M1M3Q7
names: Similarity
messages: Belongs to the CDV3 family.

29088:CXCL10
gene id: 29088:CXCL10
uniprot id: A0A2Y9I986
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

29088:TNKS2
gene id: 29088:TNKS2
uniprot id: A0A2Y9HUD1
uniprot id: A0A8M1MDV9
names: Function
names: Similarity
messages: Belongs to the ARTD/PARP family.
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

29088:GTF2F2
gene id: 29088:GTF2F2
uniprot id: A0A2Y9HP78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

29088:ST8SIA3
gene id: 29088:ST8SIA3
uniprot id: A0A2Y9GRZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

29088:LOC110589053
gene id: 29088:LOC110589053
uniprot id: A0A2Y9HU67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

29088:PGPEP1
gene id: 29088:PGPEP1
uniprot id: A0A2Y9GHZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

29088:PLA1A
gene id: 29088:PLA1A
uniprot id: A0A8M1MS79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

29088:INTS3
gene id: 29088:INTS3
uniprot id: A0A2Y9GIS2
names: Similarity
messages: Belongs to the Integrator subunit 3 family.

29088:ASB8
gene id: 29088:ASB8
uniprot id: A0A2Y9I991
uniprot id: A0A2Y9IGG9
names: Function
messages: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

29088:ENTR1
gene id: 29088:ENTR1
uniprot id: A0A8M1MRL6
uniprot id: A0A8M1MUU2
uniprot id: A0A8M1MYJ5
names: Similarity
messages: Belongs to the ENTR1 family.

29088:PIN4
gene id: 29088:PIN4
uniprot id: A0A2Y9GDL7
uniprot id: A0A8M1M1T3
uniprot id: A0A8M1M5J9
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.

29088:LOC110581682
gene id: 29088:LOC110581682
uniprot id: A0A2Y9HC03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ATP1B2
gene id: 29088:ATP1B2
uniprot id: A0A2Y9HLQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

29088:LOC110576224
gene id: 29088:LOC110576224
uniprot id: A0A2Y9GSZ0
uniprot id: A0A8M1MMW8
uniprot id: A0A8M1MPV0
names: Similarity
messages: Belongs to the globin family.

29088:CRK
gene id: 29088:CRK
uniprot id: A0A2Y9IEK4
uniprot id: A0A8M1MXB4
names: Similarity
messages: Belongs to the CRK family.

29088:SNX18
gene id: 29088:SNX18
uniprot id: A0A2Y9HRZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

29088:ARCN1
gene id: 29088:ARCN1
uniprot id: A0A2Y9HQU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

29088:PGM3
gene id: 29088:PGM3
uniprot id: A0A2Y9HI98
uniprot id: A0A8M1MKB2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

29088:YWHAQ
gene id: 29088:YWHAQ
uniprot id: A0A2Y9HNV2
names: Function
names: Similarity
messages: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
messages: Belongs to the 14-3-3 family.

29088:DDX51
gene id: 29088:DDX51
uniprot id: A0A2Y9GZB3
names: Similarity
messages: Belongs to the DEAD box helicase family.

29088:CA5B
gene id: 29088:CA5B
uniprot id: A0A2Y9GBT5
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

29088:CBLC
gene id: 29088:CBLC
uniprot id: A0A2Y9GCT5
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

29088:OTUD7A
gene id: 29088:OTUD7A
uniprot id: A0A8M1MU89
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:ALDOA
gene id: 29088:ALDOA
uniprot id: A0A2Y9I3X9
uniprot id: A0A8M1MEV9
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

29088:DSC2
gene id: 29088:DSC2
uniprot id: A0A2Y9GRN4
uniprot id: A0A2Y9GRT7
uniprot id: A0A2Y9GRW9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

29088:LOC123325297
gene id: 29088:LOC123325297
uniprot id: A0A8M1MQD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LIN28A
gene id: 29088:LIN28A
uniprot id: A0A2Y9GJB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-28 family.
messages: nucleolus

29088:HNRNPH1
gene id: 29088:HNRNPH1
uniprot id: A0A8M1MHS8
names: Subcellular Location Annotation
messages: nucleoplasm

29088:HOXA13
gene id: 29088:HOXA13
uniprot id: A0A2Y9H7F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

29088:MED1
gene id: 29088:MED1
uniprot id: A0A2Y9I7E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

29088:NR4A2
gene id: 29088:NR4A2
uniprot id: A0A2Y9I8K9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Interacts with SFPQ, NCOR2, SIN3A and HADC1. The interaction with NCOR2 increases in the absence of PITX3. Interacts with PER2.
messages: Nucleus

29088:ARSI
gene id: 29088:ARSI
uniprot id: A0A2Y9HTS7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

29088:AP2S1
gene id: 29088:AP2S1
uniprot id: A0A2Y9GCW8
uniprot id: A0A8M1MZF7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: coated pit

29088:LOC110576442
gene id: 29088:LOC110576442
uniprot id: A0A8M1MR89
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110589905
gene id: 29088:LOC110589905
uniprot id: A0A2Y9HXG5
uniprot id: A0A8M1MDB4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Inflammasome

29088:NTMT2
gene id: 29088:NTMT2
uniprot id: A0A8M1MMV1
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

29088:LOC110572877
gene id: 29088:LOC110572877
uniprot id: A0A2Y9GHI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOSIP family.
messages: Cytoplasm
messages: Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.
messages: Nucleus

29088:ZNF330
gene id: 29088:ZNF330
uniprot id: A0A2Y9GB49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOA36 family.
messages: nucleolus

29088:SLC39A4
gene id: 29088:SLC39A4
uniprot id: A0A2Y9H3I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

29088:LOC110575000
gene id: 29088:LOC110575000
uniprot id: A0A8M1MBN4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

29088:LOC110591261
gene id: 29088:LOC110591261
uniprot id: A0A2Y9I1Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

29088:NMNAT3
gene id: 29088:NMNAT3
uniprot id: A0A2Y9G5W6
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

29088:DMRTC2
gene id: 29088:DMRTC2
uniprot id: A0A2Y9H8A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

29088:NKD1
gene id: 29088:NKD1
uniprot id: A0A2Y9IBI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

29088:TK2
gene id: 29088:TK2
uniprot id: A0A2Y9ICL8
uniprot id: A0A2Y9IJB0
uniprot id: A0A8M1MXJ0
uniprot id: A0A8M1MZH7
names: Similarity
messages: Belongs to the DCK/DGK family.

29088:LOC110576417
gene id: 29088:LOC110576417
uniprot id: A0A2Y9GPS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MEP1B
gene id: 29088:MEP1B
uniprot id: A0A2Y9GX58
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:LOC110575808
gene id: 29088:LOC110575808
uniprot id: A0A2Y9GTE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TRH
gene id: 29088:TRH
uniprot id: A0A2Y9HGD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRH family.
messages: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
messages: Secreted

29088:BRCC3
gene id: 29088:BRCC3
uniprot id: A0A2Y9GGX4
uniprot id: A0A2Y9GGY6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M67A family. BRCC36 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Component of the BRCA1-A complex. Component of the BRISC complex. Both the BRCA1-A complex and the BRISC complex bind polyubiquitin.
messages: Cytoplasm
messages: Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the brca1-bard1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). Catalytic subunit of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex. The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1.
messages: Nucleus
messages: spindle pole

29088:TH
gene id: 29088:TH
uniprot id: A0A8M1MNJ3
uniprot id: A0A8M1MNK2
uniprot id: A0A8M1MXG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region
messages: synaptic vesicle

29088:FAM72A
gene id: 29088:FAM72A
uniprot id: A0A2Y9GSK3
uniprot id: A0A2Y9GWL8
uniprot id: A0A2Y9GY56
names: Similarity
messages: Belongs to the FAM72 family.

29088:GGA2
gene id: 29088:GGA2
uniprot id: A0A8M1MEM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

29088:LOC110570552
gene id: 29088:LOC110570552
uniprot id: A0A2Y9G5G7
uniprot id: A0A2Y9G7Y5
uniprot id: A0A2Y9G928
uniprot id: A0A8M1MCC1
names: Similarity
messages: Belongs to the SEC2 family.

29088:SRRT
gene id: 29088:SRRT
uniprot id: A0A2Y9GA12
uniprot id: A0A2Y9GA38
uniprot id: A0A2Y9GA56
uniprot id: A0A2Y9GDV8
names: Similarity
messages: Belongs to the ARS2 family.

29088:INPP5B
gene id: 29088:INPP5B
uniprot id: A0A8M1M7S0
uniprot id: A0A8M1M807
uniprot id: A0A8M1MA65
uniprot id: A0A8M1MG30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

29088:RNF40
gene id: 29088:RNF40
uniprot id: A0A2Y9HWP9
uniprot id: A0A2Y9HWX7
uniprot id: A0A8M1MGA2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BRE1 family.
messages: Component of the RNF20/40 complex (also known as BRE1 complex) probably composed of 2 copies of RNF20/BRE1A and 2 copies of RNF40/BRE1B. Interacts with UBE2E1/UBCH6.
messages: Nucleus

29088:RBBP8
gene id: 29088:RBBP8
uniprot id: A0A2Y9GR78
uniprot id: A0A2Y9GRA8
uniprot id: A0A8M1MTN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COM1/SAE2/CtIP family.
messages: Nucleus

29088:CHSY1
gene id: 29088:CHSY1
uniprot id: A0A8M1MMP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

29088:APRT
gene id: 29088:APRT
uniprot id: A0A2Y9I296
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm

29088:SLC27A1
gene id: 29088:SLC27A1
uniprot id: A0A8M1MHX5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

29088:MMP21
gene id: 29088:MMP21
uniprot id: A0A2Y9I691
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Cytoplasm
messages: Melanosome

29088:TMEM39A
gene id: 29088:TMEM39A
uniprot id: A0A2Y9HEA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

29088:TENM1
gene id: 29088:TENM1
uniprot id: A0A2Y9GUV5
uniprot id: A0A2Y9GWJ2
uniprot id: A0A2Y9GWJ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:PSMC5
gene id: 29088:PSMC5
uniprot id: A0A2Y9G568
uniprot id: A0A2Y9G5N9
uniprot id: A0A2Y9G8U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

29088:CELF4
gene id: 29088:CELF4
uniprot id: A0A2Y9GRS9
uniprot id: A0A2Y9GRX3
uniprot id: A0A2Y9GRX8
uniprot id: A0A2Y9GS05
uniprot id: A0A2Y9GVV7
uniprot id: A0A2Y9GVW3
uniprot id: A0A2Y9GXH9
uniprot id: A0A8M1MSQ5
uniprot id: A0A8M1MSR0
uniprot id: A0A8M1MSR1
uniprot id: A0A8M1MSR5
uniprot id: A0A8M1MSR6
uniprot id: A0A8M1MSS0
uniprot id: A0A8M1MSS1
uniprot id: A0A8M1MSS6
uniprot id: A0A8M1MST0
uniprot id: A0A8M1MST1
uniprot id: A0A8M1MST8
uniprot id: A0A8M1MST9
uniprot id: A0A8M1MSU3
uniprot id: A0A8M1MSU4
uniprot id: A0A8M1MSU7
uniprot id: A0A8M1MSU9
uniprot id: A0A8M1MSV4
uniprot id: A0A8M1MUJ6
uniprot id: A0A8M1MUK1
uniprot id: A0A8M1MUK6
uniprot id: A0A8M1MUL1
uniprot id: A0A8M1MUL6
uniprot id: A0A8M1MUM1
uniprot id: A0A8M1MUM8
uniprot id: A0A8M1MUN3
uniprot id: A0A8M1MUN8
uniprot id: A0A8M1MVX5
uniprot id: A0A8M1MVY0
uniprot id: A0A8M1MVY5
uniprot id: A0A8M1MVZ5
uniprot id: A0A8M1MVZ9
uniprot id: A0A8M1MW05
uniprot id: A0A8M1MW10
uniprot id: A0A8M1MW14
uniprot id: A0A8M1MYS4
uniprot id: A0A8M1MYS5
uniprot id: A0A8M1MYS6
uniprot id: A0A8M1MYS7
uniprot id: A0A8M1MYS8
uniprot id: A0A8M1MYS9
uniprot id: A0A8M1MYT0
uniprot id: A0A8M1MYT1
uniprot id: A0A8M1MYT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

29088:FDPS
gene id: 29088:FDPS
uniprot id: A0A2Y9GF80
uniprot id: A0A2Y9GK28
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

29088:LOC110572239
gene id: 29088:LOC110572239
uniprot id: A0A2Y9GAZ6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

29088:SMIM8
gene id: 29088:SMIM8
uniprot id: A0A2Y9HB94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM8 family.
messages: Membrane

29088:CPO
gene id: 29088:CPO
uniprot id: A0A2Y9IBT5
names: Similarity
messages: Belongs to the peptidase M14 family.

29088:TMED2
gene id: 29088:TMED2
uniprot id: A0A2Y9HRF1
uniprot id: A0A8M1MSH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

29088:LOC110576675
gene id: 29088:LOC110576675
uniprot id: A0A2Y9GUM6
names: Similarity
messages: Belongs to the actin family.

29088:GPR3
gene id: 29088:GPR3
uniprot id: A0A2Y9GJD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:NME4
gene id: 29088:NME4
uniprot id: A0A2Y9HQJ6
names: Similarity
messages: Belongs to the NDK family.

29088:TAS2R7
gene id: 29088:TAS2R7
uniprot id: A0A2Y9H471
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
messages: Membrane

29088:VARS2
gene id: 29088:VARS2
uniprot id: A0A2Y9HTY3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

29088:LOC110579044
gene id: 29088:LOC110579044
uniprot id: A0A8M1M8S2
names: Similarity
messages: Belongs to the canopy family.

29088:PLA2G4B
gene id: 29088:PLA2G4B
uniprot id: A0A2Y9HI21
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

29088:IMMP1L
gene id: 29088:IMMP1L
uniprot id: A0A2Y9GP05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

29088:PRDX2
gene id: 29088:PRDX2
uniprot id: A0A2Y9IFF3
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

29088:POU3F3
gene id: 29088:POU3F3
uniprot id: A0A8M1MM83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

29088:ALG11
gene id: 29088:ALG11
uniprot id: A0A2Y9G4M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

29088:GLIPR1
gene id: 29088:GLIPR1
uniprot id: A0A2Y9G5C9
names: Similarity
messages: Belongs to the CRISP family.

29088:LOC110582412
gene id: 29088:LOC110582412
uniprot id: A0A8M1MTK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:MRPL4
gene id: 29088:MRPL4
uniprot id: A0A2Y9IHE1
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

29088:PRKG2
gene id: 29088:PRKG2
uniprot id: A0A2Y9I250
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

29088:NEU4
gene id: 29088:NEU4
uniprot id: A0A2Y9G6N3
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

29088:SUDS3
gene id: 29088:SUDS3
uniprot id: A0A2Y9I581
names: Subcellular Location Annotation
messages: Nucleus

29088:EPHB3
gene id: 29088:EPHB3
uniprot id: A0A8M1MBZ5
names: Subcellular Location Annotation
messages: Membrane

29088:DEFB134
gene id: 29088:DEFB134
uniprot id: A0A2Y9HXT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

29088:SGSH
gene id: 29088:SGSH
uniprot id: A0A2Y9GBQ7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

29088:MARCKS
gene id: 29088:MARCKS
uniprot id: A0A2Y9HIA8
names: Similarity
messages: Belongs to the MARCKS family.

29088:ZNF830
gene id: 29088:ZNF830
uniprot id: A0A2Y9I813
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

29088:LOC110582099
gene id: 29088:LOC110582099
uniprot id: A0A2Y9H7R4
uniprot id: A0A2Y9H7S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

29088:CNEP1R1
gene id: 29088:CNEP1R1
uniprot id: A0A8M1MW65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNEP1R1 family.
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane

29088:ASF1A
gene id: 29088:ASF1A
uniprot id: A0A2Y9HBQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

29088:NSUN4
gene id: 29088:NSUN4
uniprot id: A0A2Y9GQE4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

29088:NDUFA12
gene id: 29088:NDUFA12
uniprot id: A0A2Y9GVG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:LOC110584341
gene id: 29088:LOC110584341
uniprot id: A0A2Y9HEL2
names: Similarity
messages: Belongs to the intermediate filament family.

29088:SIX4
gene id: 29088:SIX4
uniprot id: A0A2Y9I6J9
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110586685
gene id: 29088:LOC110586685
uniprot id: A0A8M1MHS6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:MYO1G
gene id: 29088:MYO1G
uniprot id: A0A2Y9ID92
uniprot id: A0A8M1MT59
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

29088:CNTNAP4
gene id: 29088:CNTNAP4
uniprot id: A0A8M1MVW4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:PEX12
gene id: 29088:PEX12
uniprot id: A0A2Y9IF11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Peroxisome membrane
messages: Required for protein import into peroxisomes.

29088:CDH5
gene id: 29088:CDH5
uniprot id: A0A2Y9IBW0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell junction
messages: Cell membrane
messages: Membrane

29088:MS4A14
gene id: 29088:MS4A14
uniprot id: A0A2Y9GNY8
names: Similarity
messages: Belongs to the MS4A family.

29088:WDR83OS
gene id: 29088:WDR83OS
uniprot id: A0A2Y9IFB2
names: Similarity
messages: Belongs to the Asterix family.

29088:MAP4K3
gene id: 29088:MAP4K3
uniprot id: A0A2Y9HPD1
uniprot id: A0A2Y9HU95
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

29088:EFTUD2
gene id: 29088:EFTUD2
uniprot id: A0A2Y9GEI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Nucleus

29088:KIF11
gene id: 29088:KIF11
uniprot id: A0A2Y9HV53
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:TMEM86B
gene id: 29088:TMEM86B
uniprot id: A0A2Y9GFJ7
uniprot id: A0A2Y9GFQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

29088:SDC1
gene id: 29088:SDC1
uniprot id: A0A2Y9HNZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane
messages: extracellular exosome

29088:PROP1
gene id: 29088:PROP1
uniprot id: A0A2Y9H4T4
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes.

29088:SEPTIN11
gene id: 29088:SEPTIN11
uniprot id: A0A2Y9I6R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

29088:REM2
gene id: 29088:REM2
uniprot id: A0A2Y9HP61
names: Subcellular Location Annotation
messages: Cell membrane

29088:LOC110586724
gene id: 29088:LOC110586724
uniprot id: A0A8M1ML60
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS28 family.
messages: Component of the 40S small ribosomal subunit.

29088:UNC45B
gene id: 29088:UNC45B
uniprot id: A0A2Y9I8B6
uniprot id: A0A2Y9IC81
uniprot id: A0A2Y9IEY7
names: Subcellular Location Annotation
messages: A band
messages: Z line
messages: perinuclear region

29088:GAL3ST3
gene id: 29088:GAL3ST3
uniprot id: A0A2Y9GSW4
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

29088:GALR2
gene id: 29088:GALR2
uniprot id: A0A2Y9GBR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

29088:ZDHHC14
gene id: 29088:ZDHHC14
uniprot id: A0A2Y9HB27
uniprot id: A0A2Y9HBB9
uniprot id: A0A2Y9HBE3
uniprot id: A0A2Y9HHU1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

29088:ODAD4
gene id: 29088:ODAD4
uniprot id: A0A2Y9GIS9
names: Subcellular Location Annotation
messages: cilium axoneme

29088:IRF8
gene id: 29088:IRF8
uniprot id: A0A2Y9I2J8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

29088:TAGLN2
gene id: 29088:TAGLN2
uniprot id: A0A2Y9GJE8
names: Similarity
messages: Belongs to the calponin family.

29088:USP39
gene id: 29088:USP39
uniprot id: A0A2Y9HPA8
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110573676
gene id: 29088:LOC110573676
uniprot id: A0A2Y9GKK2
names: Similarity
messages: Belongs to the NLRP family.

29088:LOC110578837
gene id: 29088:LOC110578837
uniprot id: A0A2Y9GXU7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:PCSK5
gene id: 29088:PCSK5
uniprot id: A0A2Y9H0I3
uniprot id: A0A2Y9H6X1
uniprot id: A0A8M1MSB3
names: Similarity
messages: Belongs to the peptidase S8 family.

29088:GRK5
gene id: 29088:GRK5
uniprot id: A0A8M1MFB4
uniprot id: A0A8M1MHF8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

29088:ABHD3
gene id: 29088:ABHD3
uniprot id: A0A2Y9GRQ8
uniprot id: A0A8M1MSF6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

29088:NR1D1
gene id: 29088:NR1D1
uniprot id: A0A2Y9I8Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

29088:CXCR1
gene id: 29088:CXCR1
uniprot id: A0A2Y9I4B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:UTP18
gene id: 29088:UTP18
uniprot id: A0A2Y9IFL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

29088:SHOX
gene id: 29088:SHOX
uniprot id: A0A2Y9IIZ3
names: Subcellular Location Annotation
messages: Nucleus

29088:MRPS12
gene id: 29088:MRPS12
uniprot id: A0A2Y9I597
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

29088:HEG1
gene id: 29088:HEG1
uniprot id: A0A8M1MYH6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:PMS2
gene id: 29088:PMS2
uniprot id: A0A2Y9G9W0
uniprot id: A0A2Y9GCI9
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

29088:NEDD8
gene id: 29088:NEDD8
uniprot id: A0A2Y9HNT6
names: Similarity
messages: Belongs to the ubiquitin family.

29088:IL15RA
gene id: 29088:IL15RA
uniprot id: A0A8M1MJX3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:IL33
gene id: 29088:IL33
uniprot id: A0A2Y9GG18
uniprot id: A0A8M1MTM2
uniprot id: A0A8M1MUZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family. Highly divergent.
messages: Chromosome
messages: Nucleus
messages: Secreted
messages: Vesicle
messages: secretory vesicle

29088:TMEM126A
gene id: 29088:TMEM126A
uniprot id: A0A2Y9GSE4
names: Subcellular Location Annotation
messages: Membrane

29088:CCM2L
gene id: 29088:CCM2L
uniprot id: A0A8M1MWI2
names: Similarity
messages: Belongs to the CCM2 family.

29088:LOC110593042
gene id: 29088:LOC110593042
uniprot id: A0A8M1M4H3
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110575026
gene id: 29088:LOC110575026
uniprot id: A0A2Y9GK75
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:DSG4
gene id: 29088:DSG4
uniprot id: A0A2Y9GRE8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

29088:TMEM107
gene id: 29088:TMEM107
uniprot id: A0A2Y9HF96
uniprot id: A0A8M1MUQ0
uniprot id: A0A8M1MWI9
uniprot id: A0A8M1MXD3
uniprot id: A0A8M1MZ64
names: Subcellular Location Annotation
messages: Membrane

29088:SLC1A6
gene id: 29088:SLC1A6
uniprot id: A0A2Y9GID4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

29088:COL4A5
gene id: 29088:COL4A5
uniprot id: A0A2Y9G5T0
uniprot id: A0A2Y9G8Z5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

29088:CREM
gene id: 29088:CREM
uniprot id: A0A2Y9GQX3
uniprot id: A0A2Y9GQX6
uniprot id: A0A2Y9GR40
uniprot id: A0A2Y9GR72
uniprot id: A0A2Y9GR76
uniprot id: A0A2Y9GV04
uniprot id: A0A2Y9GWP0
uniprot id: A0A8M1MC60
uniprot id: A0A8M1MCA4
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110573140
gene id: 29088:LOC110573140
uniprot id: A0A2Y9GIE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

29088:APLN
gene id: 29088:APLN
uniprot id: A0A2Y9GQL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apelin family.
messages: extracellular space

29088:GALNT17
gene id: 29088:GALNT17
uniprot id: A0A2Y9HX11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:CCSER2
gene id: 29088:CCSER2
uniprot id: A0A2Y9HU38
uniprot id: A0A2Y9HUL8
uniprot id: A0A2Y9HUM1
uniprot id: A0A2Y9HZG7
uniprot id: A0A8M1MF50
names: Similarity
messages: Belongs to the CCSER family.

29088:SURF6
gene id: 29088:SURF6
uniprot id: A0A8M1MUU7
names: Similarity
messages: Belongs to the SURF6 family.

29088:LOC110570003
gene id: 29088:LOC110570003
uniprot id: A0A2Y9G469
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Monomer.

29088:ALX1
gene id: 29088:ALX1
uniprot id: A0A2Y9GVB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

29088:DDX31
gene id: 29088:DDX31
uniprot id: A0A2Y9HD79
names: Similarity
messages: Belongs to the DEAD box helicase family.

29088:KRT5
gene id: 29088:KRT5
uniprot id: A0A2Y9GWY4
uniprot id: A0A8M1MKF3
names: Similarity
messages: Belongs to the intermediate filament family.

29088:LOC110591463
gene id: 29088:LOC110591463
uniprot id: A0A2Y9I2F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

29088:LOC123325521
gene id: 29088:LOC123325521
uniprot id: A0A2Y9H3T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:RBFOX3
gene id: 29088:RBFOX3
uniprot id: A0A2Y9GBW5
uniprot id: A0A2Y9GBY5
uniprot id: A0A2Y9GEJ6
uniprot id: A0A8M1MU97
uniprot id: A0A8M1MZ32
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

29088:LOC110593419
gene id: 29088:LOC110593419
uniprot id: A0A8M1MPD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function.
messages: Nucleus

29088:POLR3G
gene id: 29088:POLR3G
uniprot id: A0A2Y9I0F7
uniprot id: A0A8M1MJ74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

29088:UXS1
gene id: 29088:UXS1
uniprot id: A0A2Y9GAI0
uniprot id: A0A2Y9GED0
uniprot id: A0A8M1MLA7
uniprot id: A0A8M1MLA9
uniprot id: A0A8M1MNA7
uniprot id: A0A8M1MPL3
uniprot id: A0A8M1MVG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

29088:CWC25
gene id: 29088:CWC25
uniprot id: A0A2Y9I7G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Nucleus

29088:LOC110580058
gene id: 29088:LOC110580058
uniprot id: A0A8M1MYA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

29088:LOC110579927
gene id: 29088:LOC110579927
uniprot id: A0A2Y9H123
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

29088:LOC110577788
gene id: 29088:LOC110577788
uniprot id: A0A2Y9GUC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

29088:EEF2KMT
gene id: 29088:EEF2KMT
uniprot id: A0A2Y9HQ49
uniprot id: A0A2Y9HWM1
uniprot id: A0A8M1MCG6
uniprot id: A0A8M1MCL7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EEF2KMT family.

29088:VPS26B
gene id: 29088:VPS26B
uniprot id: A0A2Y9HK37
names: Similarity
messages: Belongs to the VPS26 family.

29088:OCEL1
gene id: 29088:OCEL1
uniprot id: A0A2Y9GNB3
names: Similarity
messages: Belongs to the ELL/occludin family.

29088:SLC6A1
gene id: 29088:SLC6A1
uniprot id: A0A2Y9HMA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

29088:MON1A
gene id: 29088:MON1A
uniprot id: A0A2Y9GTX1
uniprot id: A0A8M1MIW4
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

29088:LOC110578832
gene id: 29088:LOC110578832
uniprot id: A0A8M1MB11
names: Similarity
messages: Belongs to the MAP7 family.

29088:LOC110576869
gene id: 29088:LOC110576869
uniprot id: A0A8M1MWR6
names: Subcellular Location Annotation
messages: Nucleus

29088:MZF1
gene id: 29088:MZF1
uniprot id: A0A2Y9H743
uniprot id: A0A2Y9H744
uniprot id: A0A8M1M0P1
names: Subcellular Location Annotation
messages: Nucleus

29088:NBR1
gene id: 29088:NBR1
uniprot id: A0A2Y9GIZ8
names: Subcellular Location Annotation
messages: Lysosome
messages: autophagosome

29088:LOC110576486
gene id: 29088:LOC110576486
uniprot id: A0A2Y9GU07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:RFC2
gene id: 29088:RFC2
uniprot id: A0A2Y9HWP6
names: Similarity
messages: Belongs to the activator 1 small subunits family.

29088:ZSCAN10
gene id: 29088:ZSCAN10
uniprot id: A0A2Y9HQV2
names: Subcellular Location Annotation
messages: Nucleus

29088:AMDHD2
gene id: 29088:AMDHD2
uniprot id: A0A2Y9HQA4
uniprot id: A0A8M1MAU5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.
messages: Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.

29088:MTUS1
gene id: 29088:MTUS1
uniprot id: A0A2Y9HDE2
uniprot id: A0A2Y9HDS2
uniprot id: A0A2Y9HJL7
uniprot id: A0A2Y9HJM0
uniprot id: A0A2Y9HJZ5
uniprot id: A0A2Y9HK01
uniprot id: A0A8M1M4G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTUS1 family.
messages: Nucleus

29088:ZDHHC7
gene id: 29088:ZDHHC7
uniprot id: A0A2Y9I7J4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

29088:LOC110577998
gene id: 29088:LOC110577998
uniprot id: A0A8M1MCA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

29088:EXO1
gene id: 29088:EXO1
uniprot id: A0A8M1MGY2
uniprot id: A0A8M1MNJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

29088:PROX2
gene id: 29088:PROX2
uniprot id: A0A8M1MJI5
names: Subcellular Location Annotation
messages: Nucleus

29088:SMARCB1
gene id: 29088:SMARCB1
uniprot id: A0A2Y9GWA1
uniprot id: A0A2Y9GWI9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF5 family.
messages: Component of the multiprotein chromatin-remodeling complexes SWI/SNF.
messages: Nucleus

29088:LOC110589295
gene id: 29088:LOC110589295
uniprot id: A0A2Y9I040
uniprot id: A0A2Y9I1P1
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:LOC110577006
gene id: 29088:LOC110577006
uniprot id: A0A8M1MYX8
names: Subcellular Location Annotation
messages: Membrane

29088:BICC1
gene id: 29088:BICC1
uniprot id: A0A8M1MF11
names: Similarity
messages: Belongs to the BicC family.

29088:F2R
gene id: 29088:F2R
uniprot id: A0A2Y9HVE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:GJB6
gene id: 29088:GJB6
uniprot id: A0A2Y9G4B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

29088:LOC110593898
gene id: 29088:LOC110593898
uniprot id: A0A8M1MVW9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

29088:CTNS
gene id: 29088:CTNS
uniprot id: A0A2Y9I7P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cystinosin family.
messages: Membrane

29088:HOXB2
gene id: 29088:HOXB2
uniprot id: A0A2Y9I759
names: Subcellular Location Annotation
messages: Nucleus

29088:ATXN10
gene id: 29088:ATXN10
uniprot id: A0A2Y9GV69
names: Function
names: Similarity
messages: Belongs to the ataxin-10 family.
messages: Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.

29088:CPT1A
gene id: 29088:CPT1A
uniprot id: A0A2Y9GTS1
uniprot id: A0A2Y9GVI9
uniprot id: A0A8M1MP89
uniprot id: A0A8M1MSI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

29088:HMGN2
gene id: 29088:HMGN2
uniprot id: A0A2Y9GPJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

29088:HAGHL
gene id: 29088:HAGHL
uniprot id: A0A2Y9HUR2
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

29088:TLR3
gene id: 29088:TLR3
uniprot id: A0A2Y9HK05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

29088:RALA
gene id: 29088:RALA
uniprot id: A0A2Y9I5R0
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

29088:AXIN1
gene id: 29088:AXIN1
uniprot id: A0A2Y9HQI8
uniprot id: A0A2Y9HWZ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus

29088:FHL5
gene id: 29088:FHL5
uniprot id: A0A2Y9HC83
names: Function
names: Subcellular Location Annotation
messages: May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner.
messages: Nucleus

29088:SLC43A3
gene id: 29088:SLC43A3
uniprot id: A0A2Y9GRR4
uniprot id: A0A8M1MRJ6
names: Subcellular Location Annotation
messages: Membrane

29088:GATA5
gene id: 29088:GATA5
uniprot id: A0A2Y9G301
names: Subcellular Location Annotation
messages: Nucleus

29088:RCAN1
gene id: 29088:RCAN1
uniprot id: A0A2Y9G4F6
uniprot id: A0A2Y9G7L1
names: Similarity
messages: Belongs to the RCAN family.

29088:TOMM20L
gene id: 29088:TOMM20L
uniprot id: A0A2Y9I4C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

29088:E2F5
gene id: 29088:E2F5
uniprot id: A0A2Y9H1G4
uniprot id: A0A2Y9H3M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

29088:MC4R
gene id: 29088:MC4R
uniprot id: A0A2Y9GW47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).

29088:CD82
gene id: 29088:CD82
uniprot id: A0A2Y9GMG1
uniprot id: A0A2Y9GRH8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:PROCA1
gene id: 29088:PROCA1
uniprot id: A0A2Y9I749
uniprot id: A0A2Y9I7Y0
uniprot id: A0A8M1MWB3
uniprot id: A0A8M1MZ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Secreted

29088:PSMB6
gene id: 29088:PSMB6
uniprot id: A0A2Y9HF50
uniprot id: A0A8M1MXC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

29088:AADAC
gene id: 29088:AADAC
uniprot id: A0A8M1MDF1
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

29088:LOC110575787
gene id: 29088:LOC110575787
uniprot id: A0A2Y9GMY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SUSD3
gene id: 29088:SUSD3
uniprot id: A0A2Y9HKS3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110591527
gene id: 29088:LOC110591527
uniprot id: A0A2Y9I2W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

29088:GAL3ST4
gene id: 29088:GAL3ST4
uniprot id: A0A2Y9GCG8
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

29088:ELOF1
gene id: 29088:ELOF1
uniprot id: A0A2Y9IAC9
uniprot id: A0A8M1MJ71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

29088:KARS1
gene id: 29088:KARS1
uniprot id: A0A2Y9IG11
uniprot id: A0A2Y9IJ44
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

29088:MAP2K3
gene id: 29088:MAP2K3
uniprot id: A0A2Y9HEE8
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:CCDC25
gene id: 29088:CCDC25
uniprot id: A0A2Y9HRU3
uniprot id: A0A2Y9HX62
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC25 family.
messages: Cell membrane
messages: Endomembrane system
messages: Interacts (via cytoplasmic region) with ILK.

29088:SMAD7
gene id: 29088:SMAD7
uniprot id: A0A2Y9GS04
uniprot id: A0A2Y9GVZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

29088:DENND6A
gene id: 29088:DENND6A
uniprot id: A0A2Y9HMH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Endosome
messages: Recycling endosome

29088:HAPLN1
gene id: 29088:HAPLN1
uniprot id: A0A2Y9HUJ8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:ELN
gene id: 29088:ELN
uniprot id: A0A2Y9HWE8
uniprot id: A0A2Y9HWF3
uniprot id: A0A2Y9HWR5
uniprot id: A0A2Y9HWS0
uniprot id: A0A2Y9HWS3
uniprot id: A0A2Y9HWW8
uniprot id: A0A2Y9HWX3
uniprot id: A0A2Y9HWX8
uniprot id: A0A2Y9I1L0
uniprot id: A0A2Y9I1L6
uniprot id: A0A2Y9I388
uniprot id: A0A2Y9I392
uniprot id: A0A8M1MCR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elastin family.
messages: Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle.
messages: extracellular matrix

29088:SLC15A2
gene id: 29088:SLC15A2
uniprot id: A0A2Y9H8Y7
uniprot id: A0A2Y9HEM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

29088:RSBN1
gene id: 29088:RSBN1
uniprot id: A0A2Y9H258
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

29088:LOC110575784
gene id: 29088:LOC110575784
uniprot id: A0A2Y9GTC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:PACSIN2
gene id: 29088:PACSIN2
uniprot id: A0A2Y9GV02
uniprot id: A0A8M1MK54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PACSIN family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: caveola
messages: cytoskeleton
messages: ruffle membrane

29088:LOC123324039
gene id: 29088:LOC123324039
uniprot id: A0A8M1M4A6
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:GINS2
gene id: 29088:GINS2
uniprot id: A0A2Y9IFZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus

29088:EN2
gene id: 29088:EN2
uniprot id: A0A2Y9HAK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

29088:MAP3K9
gene id: 29088:MAP3K9
uniprot id: A0A2Y9G8W9
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

29088:KCNT1
gene id: 29088:KCNT1
uniprot id: A0A2Y9HBK0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:GRM3
gene id: 29088:GRM3
uniprot id: A0A2Y9H1K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

29088:MAEA
gene id: 29088:MAEA
uniprot id: A0A2Y9G300
uniprot id: A0A2Y9G3F3
uniprot id: A0A2Y9G6K2
uniprot id: A0A8M1M7I9
names: Subcellular Location Annotation
messages: Nucleus matrix

29088:SENP8
gene id: 29088:SENP8
uniprot id: A0A2Y9HD73
names: Similarity
messages: Belongs to the peptidase C48 family.

29088:PARVG
gene id: 29088:PARVG
uniprot id: A0A2Y9GW54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: Cell membrane
messages: cytoskeleton

29088:VCAN
gene id: 29088:VCAN
uniprot id: A0A2Y9HUK9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:FECH
gene id: 29088:FECH
uniprot id: A0A2Y9GW30
uniprot id: A0A8M1MTR7
uniprot id: A0A8M1MWT0
uniprot id: A0A8M1MYZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

29088:BCAS2
gene id: 29088:BCAS2
uniprot id: A0A2Y9H8S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPF27 family.
messages: Nucleus

29088:ADGRG3
gene id: 29088:ADGRG3
uniprot id: A0A2Y9IBD4
names: Subcellular Location Annotation
messages: Membrane

29088:UFD1
gene id: 29088:UFD1
uniprot id: A0A2Y9HB45
names: Similarity
messages: Belongs to the UFD1 family.

29088:UROD
gene id: 29088:UROD
uniprot id: A0A2Y9GL83
uniprot id: A0A2Y9GQ10
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

29088:COQ6
gene id: 29088:COQ6
uniprot id: A0A2Y9G849
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Cell projection
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ7.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Golgi apparatus
messages: Mitochondrion inner membrane

29088:LOC110577732
gene id: 29088:LOC110577732
uniprot id: A0A8M1MC91
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

29088:LOC110579615
gene id: 29088:LOC110579615
uniprot id: A0A2Y9H0B3
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110593568
gene id: 29088:LOC110593568
uniprot id: A0A2Y9I9C0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TRIO
gene id: 29088:TRIO
uniprot id: A0A8M1MHN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm

29088:LOC110576109
gene id: 29088:LOC110576109
uniprot id: A0A2Y9GSQ3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:AMBN
gene id: 29088:AMBN
uniprot id: A0A2Y9I9E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ameloblastin family.
messages: Involved in the mineralization and structural organization of enamel.
messages: extracellular matrix

29088:LOC110584165
gene id: 29088:LOC110584165
uniprot id: A0A8M1M0S4
names: Subcellular Location Annotation
messages: flagellum

29088:LIG4
gene id: 29088:LIG4
uniprot id: A0A2Y9HIT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

29088:CHST10
gene id: 29088:CHST10
uniprot id: A0A2Y9GAG2
uniprot id: A0A2Y9GEA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:CLCA1
gene id: 29088:CLCA1
uniprot id: A0A2Y9H966
names: Similarity
messages: Belongs to the CLCR family.

29088:RPS6
gene id: 29088:RPS6
uniprot id: A0A2Y9GGA7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

29088:LOC110584880
gene id: 29088:LOC110584880
uniprot id: A0A8M1MF47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

29088:SIM1
gene id: 29088:SIM1
uniprot id: A0A2Y9HBV3
names: Subcellular Location Annotation
messages: Nucleus

29088:SUPT16H
gene id: 29088:SUPT16H
uniprot id: A0A2Y9HI44
uniprot id: A0A2Y9HIJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

29088:HOXA1
gene id: 29088:HOXA1
uniprot id: A0A2Y9H139
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Labial subfamily.
messages: Nucleus

29088:NFIX
gene id: 29088:NFIX
uniprot id: A0A2Y9IEH1
uniprot id: A0A2Y9IH82
uniprot id: A0A8M1M5H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

29088:DNER
gene id: 29088:DNER
uniprot id: A0A2Y9GHN3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:CSGALNACT1
gene id: 29088:CSGALNACT1
uniprot id: A0A2Y9GIH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

29088:NUP210
gene id: 29088:NUP210
uniprot id: A0A8M1MGF1
names: Similarity
messages: Belongs to the NUP210 family.

29088:APOA4
gene id: 29088:APOA4
uniprot id: A0A7F3SAL3
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

29088:PMEL
gene id: 29088:PMEL
uniprot id: A0A2Y9GUD9
uniprot id: A0A8M1MAC0
uniprot id: A0A8M1MCG5
uniprot id: A0A8M1MDU9
uniprot id: A0A8M1MIK5
names: Similarity
messages: Belongs to the PMEL/NMB family.

29088:GPR180
gene id: 29088:GPR180
uniprot id: A0A2Y9HIR0
names: Subcellular Location Annotation
messages: Membrane

29088:S100A2
gene id: 29088:S100A2
uniprot id: A0A2Y9GJS9
names: Similarity
messages: Belongs to the S-100 family.

29088:IGF2BP2
gene id: 29088:IGF2BP2
uniprot id: A0A2Y9H8H7
uniprot id: A0A2Y9H8L4
uniprot id: A0A2Y9H8R2
uniprot id: A0A2Y9HE91
uniprot id: A0A2Y9HFB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: P-body
messages: Stress granule

29088:LOC110584603
gene id: 29088:LOC110584603
uniprot id: A0A2Y9HLH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAM33 family.
messages: Cell membrane

29088:CRX
gene id: 29088:CRX
uniprot id: A0A2Y9GCU2
names: Subcellular Location Annotation
messages: Nucleus

29088:FAM3A
gene id: 29088:FAM3A
uniprot id: A0A8M1M4L7
uniprot id: A0A8M1M9Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

29088:AQR
gene id: 29088:AQR
uniprot id: A0A2Y9HN94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWF11 family.
messages: Identified in the spliceosome C complex. Component of the XAB2 complex, a multimeric protein complex composed of XAB2, PRPF19, AQR, ZNF830, ISY1, and PPIE.
messages: Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
messages: Nucleus

29088:SLC17A7
gene id: 29088:SLC17A7
uniprot id: A0A2Y9GG12
names: Subcellular Location Annotation
messages: Membrane

29088:MTFMT
gene id: 29088:MTFMT
uniprot id: A0A2Y9HCT2
names: Similarity
messages: Belongs to the Fmt family.

29088:LOC110591098
gene id: 29088:LOC110591098
uniprot id: A0A8M1MIG9
names: Similarity
messages: Belongs to the SGT1 family.

29088:LOC110588921
gene id: 29088:LOC110588921
uniprot id: A0A8M1MHW3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

29088:CDC42SE2
gene id: 29088:CDC42SE2
uniprot id: A0A2Y9I5M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Interacts with CDC42 (in GTP-bound form). Interacts weakly with RAC1 and not at all with RHOA.
messages: Membrane
messages: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
messages: cytoskeleton

29088:PBX1
gene id: 29088:PBX1
uniprot id: A0A2Y9HXK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

29088:TFAP2B
gene id: 29088:TFAP2B
uniprot id: A0A2Y9H7N7
uniprot id: A0A2Y9H7P8
uniprot id: A0A2Y9H7X2
uniprot id: A0A2Y9HDB4
uniprot id: A0A2Y9HEJ0
names: Similarity
messages: Belongs to the AP-2 family.

29088:DNAAF2
gene id: 29088:DNAAF2
uniprot id: A0A2Y9HZJ0
uniprot id: A0A8M1MJH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PIH1 family. Kintoun subfamily.
messages: Cytoplasm
messages: Interacts with CFAP300. Interacts with DNAI2 and HSPA1A. Interacts with DYX1C1. Interacts with PIH1D3.
messages: Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.

29088:TSPYL2
gene id: 29088:TSPYL2
uniprot id: A0A2Y9HWV9
uniprot id: A0A8M1M1K2
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

29088:LOC110571126
gene id: 29088:LOC110571126
uniprot id: A0A8M1MRI6
uniprot id: A0A8M1MX84
names: Similarity
messages: Belongs to the SH3BGR family.

29088:LOC110573970
gene id: 29088:LOC110573970
uniprot id: A0A2Y9GMD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

29088:SLA
gene id: 29088:SLA
uniprot id: A0A2Y9H4G0
names: Subcellular Location Annotation
messages: Cytoplasm

29088:BID
gene id: 29088:BID
uniprot id: A0A2Y9H373
uniprot id: A0A8M1MAV3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion outer membrane

29088:LOC110572326
gene id: 29088:LOC110572326
uniprot id: A0A8M1MJU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

29088:ALB
gene id: 29088:ALB
uniprot id: A0A2Y9I240
names: Subcellular Location Annotation
messages: Secreted

29088:DMBT1
gene id: 29088:DMBT1
uniprot id: A0A2Y9IDP3
names: Caution
names: Similarity
messages: Belongs to the DMBT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:KRT78
gene id: 29088:KRT78
uniprot id: A0A2Y9GYW7
names: Similarity
messages: Belongs to the intermediate filament family.

29088:LAMP2
gene id: 29088:LAMP2
uniprot id: A0A2Y9GSQ5
uniprot id: A0A2Y9GT31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lysosome membrane

29088:NPBWR1
gene id: 29088:NPBWR1
uniprot id: A0A2Y9GYL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:LOC110593569
gene id: 29088:LOC110593569
uniprot id: A0A8M1MAA3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:STIM1
gene id: 29088:STIM1
uniprot id: A0A2Y9IG65
uniprot id: A0A8M1MNQ3
uniprot id: A0A8M1MNQ9
uniprot id: A0A8M1MQN2
uniprot id: A0A8M1MS03
uniprot id: A0A8M1MXJ9
uniprot id: A0A8M1MXK2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:ENKD1
gene id: 29088:ENKD1
uniprot id: A0A2Y9I6I9
names: Subcellular Location Annotation
messages: cilium axoneme

29088:PDSS2
gene id: 29088:PDSS2
uniprot id: A0A8M1MR81
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

29088:LOC110582160
gene id: 29088:LOC110582160
uniprot id: A0A2Y9HDJ2
names: Similarity
messages: Belongs to the FXYD family.

29088:CTNNBL1
gene id: 29088:CTNNBL1
uniprot id: A0A2Y9GZ00
uniprot id: A0A8M1MKQ9
uniprot id: A0A8M1MP27
names: Subcellular Location Annotation
messages: Nucleus

29088:GSX2
gene id: 29088:GSX2
uniprot id: A0A2Y9I742
names: Subcellular Location Annotation
messages: Nucleus

29088:CLNS1A
gene id: 29088:CLNS1A
uniprot id: A0A2Y9I992
uniprot id: A0A2Y9IFZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pICln (TC 1.A.47) family.
messages: Nucleus

29088:MRI1
gene id: 29088:MRI1
uniprot id: A0A2Y9IF32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

29088:LOC110571974
gene id: 29088:LOC110571974
uniprot id: A0A2Y9GA83
uniprot id: A0A8M1MCW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

29088:NLGN4X
gene id: 29088:NLGN4X
uniprot id: A0A2Y9HCL1
uniprot id: A0A2Y9HET7
uniprot id: A0A8M1M1H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

29088:MANBAL
gene id: 29088:MANBAL
uniprot id: A0A2Y9GZQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0239 family.
messages: Membrane

29088:LOC110588379
gene id: 29088:LOC110588379
uniprot id: A0A8M1M671
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

29088:GJA8
gene id: 29088:GJA8
uniprot id: A0A2Y9H3B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

29088:LOC110570038
gene id: 29088:LOC110570038
uniprot id: A0A2Y9G7E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

29088:MTX2
gene id: 29088:MTX2
uniprot id: A0A2Y9I3Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

29088:MICAL3
gene id: 29088:MICAL3
uniprot id: A0A2Y9H9I2
uniprot id: A0A8M1MFR3
uniprot id: A0A8M1MKN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm
messages: Nucleus
messages: cytoskeleton

29088:GNPDA2
gene id: 29088:GNPDA2
uniprot id: A0A2Y9I0A3
uniprot id: A0A2Y9I4T5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

29088:MLEC
gene id: 29088:MLEC
uniprot id: A0A2Y9I672
uniprot id: A0A8M1MT72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the malectin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:LOC110591445
gene id: 29088:LOC110591445
uniprot id: A0A8M1M7Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

29088:HBP1
gene id: 29088:HBP1
uniprot id: A0A2Y9GHK1
uniprot id: A0A2Y9GKW3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

29088:RPL37
gene id: 29088:RPL37
uniprot id: A0A2Y9HKH2
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

29088:EIF4EBP1
gene id: 29088:EIF4EBP1
uniprot id: A0A2Y9GIA6
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

29088:NR5A2
gene id: 29088:NR5A2
uniprot id: A0A2Y9GGD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

29088:LOC110576141
gene id: 29088:LOC110576141
uniprot id: A0A2Y9GNT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:NDEL1
gene id: 29088:NDEL1
uniprot id: A0A2Y9HES1
uniprot id: A0A2Y9HF52
uniprot id: A0A2Y9HL76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: kinetochore
messages: spindle

29088:FUT8
gene id: 29088:FUT8
uniprot id: A0A8M1MJK8
uniprot id: A0A8M1MTL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 23 family.
messages: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
messages: Golgi stack membrane
messages: Membrane

29088:LOC110576104
gene id: 29088:LOC110576104
uniprot id: A0A2Y9GNY4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110581909
gene id: 29088:LOC110581909
uniprot id: A0A2Y9H748
uniprot id: A0A8M1M853
names: Subcellular Location Annotation
messages: Nucleus

29088:FAM120A
gene id: 29088:FAM120A
uniprot id: A0A8M1MS42
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

29088:FAM133B
gene id: 29088:FAM133B
uniprot id: A0A8M1MQ85
names: Similarity
messages: Belongs to the FAM133 family.

29088:POLA2
gene id: 29088:POLA2
uniprot id: A0A2Y9GNI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

29088:RDH5
gene id: 29088:RDH5
uniprot id: A0A2Y9GUC8
uniprot id: A0A8M1MDV2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:RHPN2
gene id: 29088:RHPN2
uniprot id: A0A2Y9HYR9
names: Similarity
messages: Belongs to the RHPN family.

29088:TM4SF4
gene id: 29088:TM4SF4
uniprot id: A0A2Y9GR10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

29088:LOC110582567
gene id: 29088:LOC110582567
uniprot id: A0A8M1MY19
names: Similarity
messages: Belongs to the CD200R family.

29088:ANO10
gene id: 29088:ANO10
uniprot id: A0A8M1MSF1
uniprot id: A0A8M1MYQ3
uniprot id: A0A8M1MYQ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:RAD18
gene id: 29088:RAD18
uniprot id: A0A2Y9HGI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD18 family.
messages: Nucleus

29088:LOC110575865
gene id: 29088:LOC110575865
uniprot id: A0A2Y9GMX3
uniprot id: A0A2Y9GRV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUSAP family.
messages: Cytoplasm

29088:AMFR
gene id: 29088:AMFR
uniprot id: A0A2Y9IJF9
names: Subcellular Location Annotation
messages: Membrane

29088:PRDM8
gene id: 29088:PRDM8
uniprot id: A0A2Y9I2B7
names: Subcellular Location Annotation
messages: Nucleus

29088:GLYATL3
gene id: 29088:GLYATL3
uniprot id: A0A2Y9H7F8
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

29088:ITGB8
gene id: 29088:ITGB8
uniprot id: A0A2Y9H1M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

29088:LOC110577427
gene id: 29088:LOC110577427
uniprot id: A0A8M1MA73
uniprot id: A0A8M1MAF6
uniprot id: A0A8M1MCJ5
names: Similarity
messages: Belongs to the intermediate filament family.

29088:XPO6
gene id: 29088:XPO6
uniprot id: A0A2Y9HXL7
uniprot id: A0A2Y9I404
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

29088:SNRPF
gene id: 29088:SNRPF
uniprot id: A0A2Y9GV76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

29088:HOXA9
gene id: 29088:HOXA9
uniprot id: A0A2Y9H5Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

29088:ENTPD7
gene id: 29088:ENTPD7
uniprot id: A0A2Y9HVA6
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

29088:COQ10A
gene id: 29088:COQ10A
uniprot id: A0A2Y9GUL2
uniprot id: A0A8M1MCF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

29088:SFXN1
gene id: 29088:SFXN1
uniprot id: A0A2Y9HRE1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

29088:LOC110575525
gene id: 29088:LOC110575525
uniprot id: A0A8M1M6E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

29088:EIF2AK3
gene id: 29088:EIF2AK3
uniprot id: A0A2Y9HMV8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

29088:RND3
gene id: 29088:RND3
uniprot id: A0A2Y9I894
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

29088:TAS2R1
gene id: 29088:TAS2R1
uniprot id: A0A2Y9I2X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

29088:LOC110587626
gene id: 29088:LOC110587626
uniprot id: A0A8M1M613
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

29088:RXFP1
gene id: 29088:RXFP1
uniprot id: A0A2Y9HSJ3
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:ACAP1
gene id: 29088:ACAP1
uniprot id: A0A2Y9HEJ9
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

29088:LOC110589766
gene id: 29088:LOC110589766
uniprot id: A0A2Y9HWE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

29088:RIC3
gene id: 29088:RIC3
uniprot id: A0A2Y9GU76
names: Similarity
messages: Belongs to the ric-3 family.

29088:PPP2R2A
gene id: 29088:PPP2R2A
uniprot id: A0A2Y9HS44
uniprot id: A0A2Y9HXG7
uniprot id: A0A8M1M6Z0
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

29088:ESCO2
gene id: 29088:ESCO2
uniprot id: A0A2Y9HS51
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110573137
gene id: 29088:LOC110573137
uniprot id: A0A2Y9GDW1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:RAD50
gene id: 29088:RAD50
uniprot id: A0A2Y9I0S2
uniprot id: A0A8M1MIX6
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

29088:SHKBP1
gene id: 29088:SHKBP1
uniprot id: A0A2Y9I4Z4
names: Similarity
messages: Belongs to the KCTD3 family.

29088:PLPPR1
gene id: 29088:PLPPR1
uniprot id: A0A2Y9H6G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Cell membrane
messages: May play a role in neurite outgrowth and neurogenesis.
messages: Membrane
messages: neuron projection

29088:DMC1
gene id: 29088:DMC1
uniprot id: A0A2Y9GZY1
uniprot id: A0A2Y9H1P8
names: Similarity
messages: Belongs to the RecA family.
messages: Belongs to the RecA family. DMC1 subfamily.

29088:ITGAM
gene id: 29088:ITGAM
uniprot id: A0A8M1MB07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

29088:FZD5
gene id: 29088:FZD5
uniprot id: A0A2Y9IBV4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:PROS1
gene id: 29088:PROS1
uniprot id: A0A2Y9GWP3
names: Caution
names: Function
messages: Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:MINPP1
gene id: 29088:MINPP1
uniprot id: A0A2Y9HQ20
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

29088:GNG10
gene id: 29088:GNG10
uniprot id: A0A2Y9H5P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

29088:AP1S1
gene id: 29088:AP1S1
uniprot id: A0A2Y9HFK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

29088:CDK2
gene id: 29088:CDK2
uniprot id: A0A2Y9GUJ7
uniprot id: A0A8M1MA38
uniprot id: A0A8M1MDU3
uniprot id: A0A8M1MIK0
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:PAX3
gene id: 29088:PAX3
uniprot id: A0A2Y9I4F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

29088:PKD1
gene id: 29088:PKD1
uniprot id: A0A8M1MF31
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:KRT15
gene id: 29088:KRT15
uniprot id: A0A2Y9GEM6
names: Similarity
messages: Belongs to the intermediate filament family.

29088:GRAMD1A
gene id: 29088:GRAMD1A
uniprot id: A0A2Y9I4J3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:SNX19
gene id: 29088:SNX19
uniprot id: A0A2Y9HRB1
uniprot id: A0A8M1MPL5
names: Similarity
messages: Belongs to the sorting nexin family.

29088:SYT14
gene id: 29088:SYT14
uniprot id: A0A2Y9GJP3
uniprot id: A0A2Y9GLD8
names: Similarity
messages: Belongs to the synaptotagmin family.

29088:LOC110586371
gene id: 29088:LOC110586371
uniprot id: A0A2Y9HKI0
uniprot id: A0A2Y9HKS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

29088:PPP1CA
gene id: 29088:PPP1CA
uniprot id: A0A2Y9GNF4
uniprot id: A0A8M1MP92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cytoplasm
messages: nucleolus
messages: nucleoplasm

29088:LOC110582093
gene id: 29088:LOC110582093
uniprot id: A0A2Y9HDC9
uniprot id: A0A2Y9HEK0
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:MRPL12
gene id: 29088:MRPL12
uniprot id: A0A2Y9GBW1
uniprot id: A0A8M1MUP4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

29088:PER3
gene id: 29088:PER3
uniprot id: A0A2Y9GP67
uniprot id: A0A8M1MB97
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:CDX4
gene id: 29088:CDX4
uniprot id: A0A2Y9GQI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

29088:THBS1
gene id: 29088:THBS1
uniprot id: A0A2Y9HIF8
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:PGM2
gene id: 29088:PGM2
uniprot id: A0A2Y9I4U3
uniprot id: A0A8M1M866
names: Similarity
messages: Belongs to the phosphohexose mutase family.

29088:GALNT7
gene id: 29088:GALNT7
uniprot id: A0A2Y9HYN3
uniprot id: A0A8M1M423
uniprot id: A0A8M1M7Q2
uniprot id: A0A8M1MBQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:LOC110586906
gene id: 29088:LOC110586906
uniprot id: A0A2Y9HMB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

29088:MYO1D
gene id: 29088:MYO1D
uniprot id: A0A2Y9I814
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

29088:LOC110587122
gene id: 29088:LOC110587122
uniprot id: A0A8M1MMZ5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:VPS13C
gene id: 29088:VPS13C
uniprot id: A0A8M1MN07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS13 family.
messages: Lipid droplet

29088:MRS2
gene id: 29088:MRS2
uniprot id: A0A2Y9HSA5
uniprot id: A0A8M1MHL4
uniprot id: A0A8M1MKZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

29088:HEATR5B
gene id: 29088:HEATR5B
uniprot id: A0A2Y9HP87
names: Similarity
messages: Belongs to the HEATR5 family.

29088:GLI3
gene id: 29088:GLI3
uniprot id: A0A2Y9I5S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus

29088:CDC42EP4
gene id: 29088:CDC42EP4
uniprot id: A0A2Y9G532
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

29088:LOC110573098
gene id: 29088:LOC110573098
uniprot id: A0A8M1M5I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB5 displays a chymotrypsin-like activity.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

29088:MAML3
gene id: 29088:MAML3
uniprot id: A0A8M1M726
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

29088:CD46
gene id: 29088:CD46
uniprot id: A0A8M1MG04
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SLC35B3
gene id: 29088:SLC35B3
uniprot id: A0A2Y9HST1
uniprot id: A0A2Y9HU32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

29088:RIN1
gene id: 29088:RIN1
uniprot id: A0A2Y9GSE6
uniprot id: A0A8M1MRR8
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

29088:FREM3
gene id: 29088:FREM3
uniprot id: A0A2Y9G7H0
names: Similarity
messages: Belongs to the FRAS1 family.

29088:DGUOK
gene id: 29088:DGUOK
uniprot id: A0A2Y9HTE7
uniprot id: A0A8M1MLE1
names: Similarity
messages: Belongs to the DCK/DGK family.

29088:LOC123323388
gene id: 29088:LOC123323388
uniprot id: A0A8M1M3K2
names: Similarity
messages: Belongs to the SPT20 family.

29088:LOC110584690
gene id: 29088:LOC110584690
uniprot id: A0A2Y9HFL2
names: Similarity
messages: Belongs to the ATG8 family.

29088:TRIM67
gene id: 29088:TRIM67
uniprot id: A0A2Y9HJN5
names: Subcellular Location Annotation
messages: cytoskeleton

29088:LDAF1
gene id: 29088:LDAF1
uniprot id: A0A2Y9H874
uniprot id: A0A2Y9HDW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDAF1 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Membrane

29088:NOTUM
gene id: 29088:NOTUM
uniprot id: A0A2Y9GFZ3
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

29088:LOC110592784
gene id: 29088:LOC110592784
uniprot id: A0A2Y9I787
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tdpoz family.
messages: Nucleus speckle

29088:TOMM5
gene id: 29088:TOMM5
uniprot id: A0A2Y9HAM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

29088:ADGRA2
gene id: 29088:ADGRA2
uniprot id: A0A2Y9GDT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

29088:XPNPEP2
gene id: 29088:XPNPEP2
uniprot id: A0A2Y9GQD9
names: Similarity
messages: Belongs to the peptidase M24B family.

29088:PFDN6
gene id: 29088:PFDN6
uniprot id: A0A2Y9GM26
uniprot id: A0A2Y9GSJ5
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

29088:SUPT3H
gene id: 29088:SUPT3H
uniprot id: A0A2Y9HE68
names: Subcellular Location Annotation
messages: Nucleus

29088:ZAN
gene id: 29088:ZAN
uniprot id: A0A8M1MDS2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:DPT
gene id: 29088:DPT
uniprot id: A0A2Y9GK18
names: Similarity
messages: Belongs to the dermatopontin family.

29088:LOC110578423
gene id: 29088:LOC110578423
uniprot id: A0A8M1M7J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

29088:MCM5
gene id: 29088:MCM5
uniprot id: A0A2Y9GVF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

29088:ATP6V0A1
gene id: 29088:ATP6V0A1
uniprot id: A0A2Y9GEG7
uniprot id: A0A8M1MUX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

29088:CHRNA6
gene id: 29088:CHRNA6
uniprot id: A0A2Y9GDQ9
uniprot id: A0A2Y9GDX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:SNX20
gene id: 29088:SNX20
uniprot id: A0A2Y9IDH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

29088:ATG4B
gene id: 29088:ATG4B
uniprot id: A0A2Y9G6S4
uniprot id: A0A2Y9G6T2
uniprot id: A0A8M1MB08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Endoplasmic reticulum
messages: Mitochondrion
messages: autophagosome
messages: cytosol

29088:CXCR5
gene id: 29088:CXCR5
uniprot id: A0A2Y9HR60
uniprot id: A0A2Y9HS17
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:MID1
gene id: 29088:MID1
uniprot id: A0A2Y9GKT0
uniprot id: A0A2Y9GPF9
names: Function
names: Subcellular Location Annotation
messages: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
messages: cytoskeleton

29088:IRF2BPL
gene id: 29088:IRF2BPL
uniprot id: A0A2Y9G953
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

29088:LAPTM4A
gene id: 29088:LAPTM4A
uniprot id: A0A2Y9HU69
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

29088:FBXO31
gene id: 29088:FBXO31
uniprot id: A0A2Y9IBI0
names: Similarity
names: Subunit
messages: Belongs to the FBXO31 family.
messages: Part of a SCF (SKP1-cullin-F-box) protein ligase complex.

29088:ITPR2
gene id: 29088:ITPR2
uniprot id: A0A8M1MFM1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

29088:LCA5
gene id: 29088:LCA5
uniprot id: A0A2Y9HC66
names: Similarity
messages: Belongs to the LCA5 family.

29088:ERAP1
gene id: 29088:ERAP1
uniprot id: A0A2Y9I721
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

29088:ARL9
gene id: 29088:ARL9
uniprot id: A0A2Y9I039
uniprot id: A0A2Y9I0F5
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

29088:EPS8L2
gene id: 29088:EPS8L2
uniprot id: A0A2Y9H8C9
uniprot id: A0A8M1MPI8
names: Similarity
messages: Belongs to the EPS8 family.

29088:SYVN1
gene id: 29088:SYVN1
uniprot id: A0A2Y9GTM4
uniprot id: A0A8M1MP57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRD1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:AARS2
gene id: 29088:AARS2
uniprot id: A0A2Y9H7L2
names: Caution
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: ISGylated.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

29088:TMEM150B
gene id: 29088:TMEM150B
uniprot id: A0A8M1MVR2
names: Subcellular Location Annotation
messages: Membrane

29088:AHSA2P
gene id: 29088:AHSA2P
uniprot id: A0A2Y9HZP2
names: Similarity
messages: Belongs to the AHA1 family.

29088:LOC110585771
gene id: 29088:LOC110585771
uniprot id: A0A8M1MDW3
names: Subcellular Location Annotation
messages: Nucleus

29088:LMF2
gene id: 29088:LMF2
uniprot id: A0A2Y9GWD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Membrane

29088:GFRAL
gene id: 29088:GFRAL
uniprot id: A0A2Y9H7N3
names: Similarity
messages: Belongs to the GDNFR family.

29088:TBR1
gene id: 29088:TBR1
uniprot id: A0A2Y9I588
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

29088:TAF10
gene id: 29088:TAF10
uniprot id: A0A2Y9GVV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Nucleus
messages: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription.

29088:GTF3C5
gene id: 29088:GTF3C5
uniprot id: A0A2Y9H5G1
uniprot id: A0A2Y9H5H3
uniprot id: A0A2Y9H5J5
uniprot id: A0A2Y9HAW5
uniprot id: A0A8M1MUC4
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110583667
gene id: 29088:LOC110583667
uniprot id: A0A8M1MLR4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with chaperones HSP70 and HSP90; this interaction is required for initial targeting to mitochondria.
messages: Microsome membrane
messages: Mitochondrion inner membrane
messages: The omega-1 hydroxylase activity is stimulated by cytochrome b5.

29088:LOC110588497
gene id: 29088:LOC110588497
uniprot id: A0A8M1M7Q7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

29088:MSI2
gene id: 29088:MSI2
uniprot id: A0A2Y9I830
uniprot id: A0A2Y9I8U0
uniprot id: A0A8M1MWT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

29088:RFC5
gene id: 29088:RFC5
uniprot id: A0A2Y9HRD4
uniprot id: A0A8M1MTT0
names: Similarity
messages: Belongs to the activator 1 small subunits family.

29088:NEURL2
gene id: 29088:NEURL2
uniprot id: A0A2Y9GZY4
names: Subcellular Location Annotation
messages: Cytoplasm

29088:LOC110591009
gene id: 29088:LOC110591009
uniprot id: A0A8M1MPM7
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.
messages: Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.

29088:JAKMIP1
gene id: 29088:JAKMIP1
uniprot id: A0A2Y9G2H3
uniprot id: A0A2Y9G2M7
uniprot id: A0A2Y9G538
uniprot id: A0A2Y9G674
names: Similarity
messages: Belongs to the JAKMIP family.

29088:ZNF287
gene id: 29088:ZNF287
uniprot id: A0A2Y9HEV8
names: Subcellular Location Annotation
messages: Nucleus

29088:TMEM201
gene id: 29088:TMEM201
uniprot id: A0A2Y9GP44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM201 family.
messages: Membrane
messages: Nucleus inner membrane

29088:RDH12
gene id: 29088:RDH12
uniprot id: A0A2Y9G894
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:DIP2B
gene id: 29088:DIP2B
uniprot id: A0A2Y9I9H7
uniprot id: A0A8M1MBY3
uniprot id: A0A8M1MC33
names: Similarity
messages: Belongs to the DIP2 family.

29088:MMP8
gene id: 29088:MMP8
uniprot id: A0A2Y9HK46
names: Similarity
messages: Belongs to the peptidase M10A family.

29088:LOC110585359
gene id: 29088:LOC110585359
uniprot id: A0A2Y9HP55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TNPO2
gene id: 29088:TNPO2
uniprot id: A0A8M1M632
uniprot id: A0A8M1MDV7
uniprot id: A0A8M1ME15
names: Subcellular Location Annotation
messages: Cytoplasm

29088:KIF3B
gene id: 29088:KIF3B
uniprot id: A0A2Y9GYZ5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:PNRC1
gene id: 29088:PNRC1
uniprot id: A0A2Y9HAT3
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC123325527
gene id: 29088:LOC123325527
uniprot id: A0A8M1MKE3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:LOC110593657
gene id: 29088:LOC110593657
uniprot id: A0A2Y9IE02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAGP family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane

29088:ESF1
gene id: 29088:ESF1
uniprot id: A0A2Y9HXD4
uniprot id: A0A2Y9I2E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

29088:B4GALT1
gene id: 29088:B4GALT1
uniprot id: A0A2Y9H5V8
uniprot id: A0A8M1MRL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

29088:SLC5A3
gene id: 29088:SLC5A3
uniprot id: A0A2Y9G673
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

29088:NPY2R
gene id: 29088:NPY2R
uniprot id: A0A2Y9HXQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:MDH2
gene id: 29088:MDH2
uniprot id: A0A2Y9I3X0
uniprot id: A0A8M1MGD2
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

29088:TXN
gene id: 29088:TXN
uniprot id: A0A2Y9H5A5
names: Similarity
messages: Belongs to the thioredoxin family.

29088:CAND2
gene id: 29088:CAND2
uniprot id: A0A2Y9HFY7
uniprot id: A0A8M1MEK2
uniprot id: A0A8M1MI45
names: Similarity
messages: Belongs to the CAND family.

29088:CSTF2
gene id: 29088:CSTF2
uniprot id: A0A2Y9GAR1
uniprot id: A0A8M1M561
names: Subcellular Location Annotation
messages: Nucleus

29088:DSE
gene id: 29088:DSE
uniprot id: A0A2Y9HB26
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

29088:LTV1
gene id: 29088:LTV1
uniprot id: A0A2Y9HBM7
names: Similarity
messages: Belongs to the LTV1 family.

29088:ZFYVE26
gene id: 29088:ZFYVE26
uniprot id: A0A2Y9G8Z0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with AP5Z1, AP5B1, AP5S1 and SPG11. Interacts with TTC19 and KIF13A.
messages: Midbody
messages: Phosphatidylinositol 3-phosphate-binding protein required for the abcission step in cytokinesis: recruited to the midbody during cytokinesis and acts as a regulator of abcission. May also be required for efficient homologous recombination DNA double-strand break repair.

29088:ONECUT1
gene id: 29088:ONECUT1
uniprot id: A0A2Y9HDH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

29088:LTB4R2
gene id: 29088:LTB4R2
uniprot id: A0A2Y9HNP8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:CUL3
gene id: 29088:CUL3
uniprot id: A0A2Y9GHN9
uniprot id: A0A2Y9GMS7
uniprot id: A0A8M1M757
names: Similarity
messages: Belongs to the cullin family.

29088:CASP9
gene id: 29088:CASP9
uniprot id: A0A2Y9GP96
uniprot id: A0A8M1M7H8
uniprot id: A0A8M1M7R8
names: Similarity
messages: Belongs to the peptidase C14A family.

29088:LOC110586900
gene id: 29088:LOC110586900
uniprot id: A0A2Y9HU37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

29088:SERINC5
gene id: 29088:SERINC5
uniprot id: A0A2Y9I1K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Cell membrane
messages: Membrane

29088:LOC123324552
gene id: 29088:LOC123324552
uniprot id: A0A8M1MBA3
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

29088:EXOSC9
gene id: 29088:EXOSC9
uniprot id: A0A2Y9GDS2
names: Subcellular Location Annotation
messages: Cytoplasm

29088:LOC110593062
gene id: 29088:LOC110593062
uniprot id: A0A2Y9I7L5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110588800
gene id: 29088:LOC110588800
uniprot id: A0A2Y9HYB6
names: Similarity
messages: Belongs to the CD225/Dispanin family.

29088:PDE7A
gene id: 29088:PDE7A
uniprot id: A0A2Y9H1C3
uniprot id: A0A8M1MGU3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

29088:GTF2H3
gene id: 29088:GTF2H3
uniprot id: A0A2Y9HWI1
uniprot id: A0A2Y9HY64
uniprot id: A0A8M1MT15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
messages: Nucleus
messages: Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7.

29088:IFITM10
gene id: 29088:IFITM10
uniprot id: A0A8M1MQM2
names: Similarity
messages: Belongs to the CD225/Dispanin family.

29088:TAS2R8
gene id: 29088:TAS2R8
uniprot id: A0A2Y9H3C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

29088:QSOX2
gene id: 29088:QSOX2
uniprot id: A0A2Y9H4X9
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

29088:LOC110575805
gene id: 29088:LOC110575805
uniprot id: A0A2Y9GN00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:FZD2
gene id: 29088:FZD2
uniprot id: A0A2Y9GE49
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:GPR21
gene id: 29088:GPR21
uniprot id: A0A2Y9H6W7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:SLC2A9
gene id: 29088:SLC2A9
uniprot id: A0A2Y9G2L5
uniprot id: A0A2Y9G322
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

29088:TTYH2
gene id: 29088:TTYH2
uniprot id: A0A2Y9G8Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

29088:RNF43
gene id: 29088:RNF43
uniprot id: A0A2Y9I7Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZNRF3 family.
messages: Cell membrane

29088:LOC110593284
gene id: 29088:LOC110593284
uniprot id: A0A2Y9IFP7
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

29088:LOC110581675
gene id: 29088:LOC110581675
uniprot id: A0A2Y9HBZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ACVR2B
gene id: 29088:ACVR2B
uniprot id: A0A2Y9ICY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

29088:ARPC1B
gene id: 29088:ARPC1B
uniprot id: A0A8M1MDG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: Nucleus
messages: cytoskeleton

29088:KIF20A
gene id: 29088:KIF20A
uniprot id: A0A2Y9I5E4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:DYNC1LI2
gene id: 29088:DYNC1LI2
uniprot id: A0A2Y9I7T1
uniprot id: A0A2Y9IEG2
uniprot id: A0A8M1M330
uniprot id: A0A8M1M897
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

29088:MORF4L2
gene id: 29088:MORF4L2
uniprot id: A0A2Y9H5P8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the NuA4 histone acetyltransferase complex which contains the catalytic subunit KAT5/TIP60 and the subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A, MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41 and VPS72/YL1. The NuA4 complex interacts with MYC and the adenovirus E1A protein. MORF4L1 may also participate in the formation of NuA4 related complexes which lack the KAT5/TIP60 catalytic subunit, but which include the SWI/SNF related protein SRCAP. Component of the MSIN3A histone deacetylase complex, which includes SIN3A, HDAC2, ARID4B, MORF4L1, RBBP4/RbAp48, and RBBP7/RbAp46. Interacts with MRFAP1 and RB1. May also interact with one or more as yet undefined members of the TLE (transducin-like enhancer of split) family of transcriptional repressors.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also a component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
messages: Nucleus

29088:LOC110575410
gene id: 29088:LOC110575410
uniprot id: A0A2Y9GQH0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

29088:LOC110581175
gene id: 29088:LOC110581175
uniprot id: A0A2Y9H4R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:FAM110B
gene id: 29088:FAM110B
uniprot id: A0A2Y9H2P2
names: Similarity
messages: Belongs to the FAM110 family.

29088:STMN3
gene id: 29088:STMN3
uniprot id: A0A2Y9G336
uniprot id: A0A8M1MPB3
names: Function
names: Similarity
messages: Belongs to the stathmin family.
messages: Exhibits microtubule-destabilizing activity, which is antagonized by STAT3.

29088:CNOT2
gene id: 29088:CNOT2
uniprot id: A0A2Y9G5N0
uniprot id: A0A2Y9G5N2
uniprot id: A0A2Y9G846
uniprot id: A0A2Y9G991
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

29088:P3H3
gene id: 29088:P3H3
uniprot id: A0A2Y9H3U8
names: Similarity
messages: Belongs to the leprecan family.

29088:PON2
gene id: 29088:PON2
uniprot id: A0A2Y9H7I5
uniprot id: A0A8M1MY36
names: Cofactor
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.

29088:LOC110588289
gene id: 29088:LOC110588289
uniprot id: A0A2Y9HWI6
uniprot id: A0A8M1MT35
names: Similarity
names: Subunit
messages: Belongs to the rtf2 family.
messages: Interacts with DDI2; probably also interacts with DDI1.

29088:SOSTDC1
gene id: 29088:SOSTDC1
uniprot id: A0A2Y9H1D2
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110577348
gene id: 29088:LOC110577348
uniprot id: A0A8M1MH99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

29088:LOC110581288
gene id: 29088:LOC110581288
uniprot id: A0A2Y9HBS8
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110587553
gene id: 29088:LOC110587553
uniprot id: A0A8M1MP33
names: Similarity
messages: Belongs to the NDK family.

29088:RPL4
gene id: 29088:RPL4
uniprot id: A0A2Y9HCM6
uniprot id: A0A8M1MIU2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

29088:CPSF4L
gene id: 29088:CPSF4L
uniprot id: A0A2Y9G7K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

29088:XNDC1N
gene id: 29088:XNDC1N
uniprot id: A0A2Y9IG20
names: Subcellular Location Annotation
messages: Membrane

29088:KRT4
gene id: 29088:KRT4
uniprot id: A0A2Y9GSQ0
names: Similarity
messages: Belongs to the intermediate filament family.

29088:CUL4A
gene id: 29088:CUL4A
uniprot id: A0A2Y9HIV4
uniprot id: A0A8M1MA76
uniprot id: A0A8M1MEK7
names: Similarity
messages: Belongs to the cullin family.

29088:PDIK1L
gene id: 29088:PDIK1L
uniprot id: A0A2Y9GJB2
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:TRAF5
gene id: 29088:TRAF5
uniprot id: A0A2Y9GJP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

29088:TEF
gene id: 29088:TEF
uniprot id: A0A2Y9GUY7
uniprot id: A0A2Y9GV49
uniprot id: A0A2Y9GZ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

29088:FOXM1
gene id: 29088:FOXM1
uniprot id: A0A2Y9H3P4
uniprot id: A0A8M1MAL0
uniprot id: A0A8M1MAU1
uniprot id: A0A8M1MCX1
uniprot id: A0A8M1MEB0
names: Subcellular Location Annotation
messages: Nucleus

29088:SCFD1
gene id: 29088:SCFD1
uniprot id: A0A2Y9HPC9
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

29088:IL17RB
gene id: 29088:IL17RB
uniprot id: A0A8M1MPT0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:NXN
gene id: 29088:NXN
uniprot id: A0A2Y9IBP0
names: Similarity
messages: Belongs to the nucleoredoxin family.

29088:SLC47A1
gene id: 29088:SLC47A1
uniprot id: A0A2Y9HL17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

29088:TLR4
gene id: 29088:TLR4
uniprot id: A0A2Y9H646
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

29088:LOC110582341
gene id: 29088:LOC110582341
uniprot id: A0A8M1MBI5
names: Similarity
messages: Belongs to the yippee family.

29088:PRPH2
gene id: 29088:PRPH2
uniprot id: A0A2Y9H7C5
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

29088:PRPF31
gene id: 29088:PRPF31
uniprot id: A0A2Y9GG11
uniprot id: A0A8M1MX65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Cajal body

29088:DKK1
gene id: 29088:DKK1
uniprot id: A0A2Y9HJN3
names: Similarity
messages: Belongs to the dickkopf family.

29088:YIF1B
gene id: 29088:YIF1B
uniprot id: A0A2Y9HYG6
uniprot id: A0A2Y9HYL0
uniprot id: A0A2Y9HYU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

29088:CSGALNACT2
gene id: 29088:CSGALNACT2
uniprot id: A0A2Y9HVG6
uniprot id: A0A2Y9I2D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

29088:LOC110587677
gene id: 29088:LOC110587677
uniprot id: A0A8M1M8M1
names: Similarity
messages: Belongs to the TMA7 family.

29088:SLC40A1
gene id: 29088:SLC40A1
uniprot id: A0A2Y9I3V1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

29088:FOXH1
gene id: 29088:FOXH1
uniprot id: A0A2Y9GY74
names: Subcellular Location Annotation
messages: Nucleus

29088:B3GNT6
gene id: 29088:B3GNT6
uniprot id: A0A2Y9IG73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:TRPC6
gene id: 29088:TRPC6
uniprot id: A0A8M1MRN4
names: Subcellular Location Annotation
messages: Membrane

29088:IL18
gene id: 29088:IL18
uniprot id: A0A2Y9HKK1
uniprot id: A0A2Y9HRB9
uniprot id: A0A2Y9HS94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-1 family.
messages: Cytoplasm
messages: Forms a ternary complex with ligand-binding receptor subunit IL18R1 and signaling receptor subunit IL18RAP at the plasma membrane. Mature IL18 first binds to IL18R1 forming a low affinity binary complex, which then interacts with IL18RAP to form a high affinity ternary complex that signals inside the cell. Interacts with cargo receptor TMED10; the interaction mediates the translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and thereby secretion.
messages: Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.
messages: Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
messages: Secreted

29088:TIMP3
gene id: 29088:TIMP3
uniprot id: A0A2Y9GUZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: Interacts with EFEMP1.
messages: extracellular matrix

29088:ALOX12B
gene id: 29088:ALOX12B
uniprot id: A0A2Y9HLG5
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:HEBP2
gene id: 29088:HEBP2
uniprot id: A0A2Y9HHN7
uniprot id: A0A8M1MHU0
names: Similarity
messages: Belongs to the HEBP family.

29088:LOC110578394
gene id: 29088:LOC110578394
uniprot id: A0A2Y9GWI2
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

29088:LOC110575613
gene id: 29088:LOC110575613
uniprot id: A0A2Y9GSP9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
messages: Enterostatin has a biological activity as a satiety signal.
messages: Forms a 1:1 stoichiometric complex with pancreatic lipase.
messages: Secreted

29088:EGFL7
gene id: 29088:EGFL7
uniprot id: A0A2Y9H4X3
uniprot id: A0A2Y9H4Y7
uniprot id: A0A8M1MYK2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SPNS2
gene id: 29088:SPNS2
uniprot id: A0A2Y9HF32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

29088:BABAM2
gene id: 29088:BABAM2
uniprot id: A0A2Y9HMP3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BABAM2 family.
messages: Component of the ARISC complex. Component of the BRCA1-A complex. Component of the BRISC complex. Binds polyubiquitin.
messages: Contains 2 ubiquitin-conjugating enzyme family-like (UEV-like) regions. These regions lack the critical Cys residues required for ubiquitination but retain the ability to bind ubiquitin.
messages: Cytoplasm
messages: May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway.
messages: Nucleus

29088:LOC110581716
gene id: 29088:LOC110581716
uniprot id: A0A8M1MUF0
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

29088:KBTBD8
gene id: 29088:KBTBD8
uniprot id: A0A2Y9HGN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KBTBD8 family.
messages: Golgi apparatus
messages: spindle

29088:CACTIN
gene id: 29088:CACTIN
uniprot id: A0A8M1MHP9
names: Similarity
messages: Belongs to the CACTIN family.

29088:SLC45A2
gene id: 29088:SLC45A2
uniprot id: A0A2Y9HIV9
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110570174
gene id: 29088:LOC110570174
uniprot id: A0A8M1MB58
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS21 family.

29088:AKAP5
gene id: 29088:AKAP5
uniprot id: A0A2Y9HZV7
names: Subcellular Location Annotation
messages: Membrane

29088:SCOC
gene id: 29088:SCOC
uniprot id: A0A8M1M3V4
uniprot id: A0A8M1M6B5
uniprot id: A0A8M1MBU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCOC family.
messages: Positive regulator of amino acid starvation-induced autophagy.
messages: trans-Golgi network

29088:CSK
gene id: 29088:CSK
uniprot id: A0A2Y9HIQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

29088:TOP2A
gene id: 29088:TOP2A
uniprot id: A0A2Y9I8D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

29088:PPP4R3A
gene id: 29088:PPP4R3A
uniprot id: A0A2Y9G902
uniprot id: A0A2Y9GBM7
uniprot id: A0A8M1MKR7
names: Similarity
messages: Belongs to the SMEK family.

29088:TLX2
gene id: 29088:TLX2
uniprot id: A0A2Y9HTL2
names: Subcellular Location Annotation
messages: Nucleus

29088:TAC1
gene id: 29088:TAC1
uniprot id: A0A2Y9H6A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted
messages: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

29088:EFEMP1
gene id: 29088:EFEMP1
uniprot id: A0A2Y9HZ30
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LYG1
gene id: 29088:LYG1
uniprot id: A0A2Y9HZ27
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

29088:C14H18orf32
gene id: 29088:C14H18orf32
uniprot id: A0A2Y9GRE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPF0729 family.
messages: Interacts with DERL1 and AMFR.
messages: May activate the NF-kappa-B signaling pathway.

29088:HSPB8
gene id: 29088:HSPB8
uniprot id: A0A2Y9I596
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Displays temperature-dependent chaperone activity.
messages: Nucleus

29088:SST
gene id: 29088:SST
uniprot id: A0A2Y9HET3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted

29088:LOC110585544
gene id: 29088:LOC110585544
uniprot id: A0A2Y9HPK5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:FAM76B
gene id: 29088:FAM76B
uniprot id: A0A2Y9G6Y2
uniprot id: A0A2Y9G7A4
uniprot id: A0A8M1MR80
uniprot id: A0A8M1MSK7
uniprot id: A0A8M1MXV9
names: Similarity
messages: Belongs to the FAM76 family.

29088:LOC110584897
gene id: 29088:LOC110584897
uniprot id: A0A2Y9HG45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

29088:ERP29
gene id: 29088:ERP29
uniprot id: A0A2Y9HRP6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Does not seem to be a disulfide isomerase.
messages: Endoplasmic reticulum lumen
messages: Homodimer.
messages: Melanosome

29088:EPHB4
gene id: 29088:EPHB4
uniprot id: A0A2Y9GA60
names: Subcellular Location Annotation
messages: Membrane

29088:FOXB1
gene id: 29088:FOXB1
uniprot id: A0A2Y9HDK6
names: Subcellular Location Annotation
messages: Nucleus

29088:SLC25A29
gene id: 29088:SLC25A29
uniprot id: A0A2Y9G8M2
uniprot id: A0A2Y9GB90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:USP4
gene id: 29088:USP4
uniprot id: A0A2Y9GTK7
uniprot id: A0A2Y9GZB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Nucleus

29088:UBLCP1
gene id: 29088:UBLCP1
uniprot id: A0A2Y9HPM2
names: Function
names: Subcellular Location Annotation
messages: Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.
messages: Nucleus

29088:UPF3A
gene id: 29088:UPF3A
uniprot id: A0A2Y9HIK9
uniprot id: A0A2Y9HIZ3
uniprot id: A0A2Y9HIZ5
uniprot id: A0A2Y9HPM1
uniprot id: A0A2Y9HPM6
uniprot id: A0A8M1M6N4
uniprot id: A0A8M1M8T5
uniprot id: A0A8M1MA72
uniprot id: A0A8M1MEK3
names: Similarity
messages: Belongs to the RENT3 family.

29088:DPPA4
gene id: 29088:DPPA4
uniprot id: A0A2Y9H9K7
names: Subcellular Location Annotation
messages: Nucleus

29088:MYO5C
gene id: 29088:MYO5C
uniprot id: A0A2Y9HCN8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

29088:MTFP1
gene id: 29088:MTFP1
uniprot id: A0A2Y9I5S3
names: Similarity
messages: Belongs to the MTFP1 family.

29088:EVX2
gene id: 29088:EVX2
uniprot id: A0A2Y9IC04
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110586195
gene id: 29088:LOC110586195
uniprot id: A0A2Y9HK57
uniprot id: A0A2Y9HK75
names: Similarity
messages: Belongs to the peptidase C14A family.

29088:LOC123323171
gene id: 29088:LOC123323171
uniprot id: A0A8M1MPP4
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

29088:LOC110583027
gene id: 29088:LOC110583027
uniprot id: A0A8M1MH15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

29088:TPD52
gene id: 29088:TPD52
uniprot id: A0A2Y9GYM1
uniprot id: A0A2Y9GYN2
uniprot id: A0A8M1MC10
uniprot id: A0A8M1MDE2
uniprot id: A0A8M1MI41
names: Similarity
messages: Belongs to the TPD52 family.

29088:POU6F1
gene id: 29088:POU6F1
uniprot id: A0A2Y9I983
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

29088:LOC110576427
gene id: 29088:LOC110576427
uniprot id: A0A2Y9GVM7
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:FMO1
gene id: 29088:FMO1
uniprot id: A0A2Y9GME9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

29088:CCN6
gene id: 29088:CCN6
uniprot id: A0A2Y9HBE2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:SLC35F1
gene id: 29088:SLC35F1
uniprot id: A0A2Y9HHR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

29088:PARP1
gene id: 29088:PARP1
uniprot id: A0A2Y9GAQ1
uniprot id: A0A2Y9GBN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARTD/PARP family.
messages: Chromosome
messages: Interacts (when auto-poly-ADP-ribosylated) with AIFM1.
messages: Nucleus
messages: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.
messages: This cleavage form irreversibly binds to DNA breaks and interferes with DNA repair, promoting DNA damage-induced apoptosis.

29088:UPF1
gene id: 29088:UPF1
uniprot id: A0A2Y9GIC8
uniprot id: A0A2Y9GIK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

29088:LOC110577834
gene id: 29088:LOC110577834
uniprot id: A0A2Y9GYR6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:NDC1
gene id: 29088:NDC1
uniprot id: A0A2Y9GK82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

29088:MUL1
gene id: 29088:MUL1
uniprot id: A0A2Y9GPE7
names: Subcellular Location Annotation
messages: Membrane

29088:ITGB5
gene id: 29088:ITGB5
uniprot id: A0A2Y9H988
uniprot id: A0A2Y9H9C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

29088:SLC14A2
gene id: 29088:SLC14A2
uniprot id: A0A2Y9GS14
uniprot id: A0A8M1MW95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

29088:SYS1
gene id: 29088:SYS1
uniprot id: A0A2Y9H0H8
uniprot id: A0A2Y9H6W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYS1 family.
messages: Golgi apparatus membrane
messages: Interacts with ARFRP1.
messages: Involved in protein trafficking. May serve as a receptor for ARFRP1.
messages: Membrane

29088:EMC8
gene id: 29088:EMC8
uniprot id: A0A2Y9IBN8
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

29088:LOC110590680
gene id: 29088:LOC110590680
uniprot id: A0A8M1MJN2
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:LOC110571185
gene id: 29088:LOC110571185
uniprot id: A0A2Y9G7T1
uniprot id: A0A2Y9GB22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

29088:LOC110590091
gene id: 29088:LOC110590091
uniprot id: A0A2Y9HY33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

29088:MAPK13
gene id: 29088:MAPK13
uniprot id: A0A2Y9GM67
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Interacts with MAPK8IP2.

29088:LOC110581696
gene id: 29088:LOC110581696
uniprot id: A0A8M1MR78
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

29088:GGT5
gene id: 29088:GGT5
uniprot id: A0A2Y9GWH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

29088:SIVA1
gene id: 29088:SIVA1
uniprot id: A0A2Y9G8P6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
messages: Nucleus

29088:LOC110585372
gene id: 29088:LOC110585372
uniprot id: A0A2Y9HHY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:THBS2
gene id: 29088:THBS2
uniprot id: A0A2Y9HAH2
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:DUXB
gene id: 29088:DUXB
uniprot id: A0A2Y9II52
names: Subcellular Location Annotation
messages: Nucleus

29088:MAB21L1
gene id: 29088:MAB21L1
uniprot id: A0A2Y9G4L3
names: Similarity
messages: Belongs to the mab-21 family.

29088:NDUFB9
gene id: 29088:NDUFB9
uniprot id: A0A2Y9H5A7
uniprot id: A0A8M1M9Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:LOC110585108
gene id: 29088:LOC110585108
uniprot id: A0A8M1MC40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

29088:LIFR
gene id: 29088:LIFR
uniprot id: A0A2Y9HJT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

29088:SLC6A18
gene id: 29088:SLC6A18
uniprot id: A0A2Y9GU08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

29088:ZP1
gene id: 29088:ZP1
uniprot id: A0A2Y9H857
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:PKLR
gene id: 29088:PKLR
uniprot id: A0A2Y9GIJ7
uniprot id: A0A2Y9GK23
names: Similarity
messages: Belongs to the pyruvate kinase family.

29088:LOC110590421
gene id: 29088:LOC110590421
uniprot id: A0A2Y9HYW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:GOLT1A
gene id: 29088:GOLT1A
uniprot id: A0A2Y9GSP6
uniprot id: A0A2Y9GSU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

29088:CILP2
gene id: 29088:CILP2
uniprot id: A0A2Y9GN28
names: Subcellular Location Annotation
messages: extracellular matrix

29088:RRP12
gene id: 29088:RRP12
uniprot id: A0A2Y9I184
uniprot id: A0A8M1MFA2
uniprot id: A0A8M1MIQ0
names: Similarity
messages: Belongs to the RRP12 family.

29088:C10H2orf68
gene id: 29088:C10H2orf68
uniprot id: A0A2Y9HNV7
names: Similarity
messages: Belongs to the UPF0561 family.

29088:LYRM2
gene id: 29088:LYRM2
uniprot id: A0A2Y9HBT9
names: Similarity
messages: Belongs to the complex I LYR family.

29088:ACOT8
gene id: 29088:ACOT8
uniprot id: A0A2Y9H3N0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

29088:HOXC12
gene id: 29088:HOXC12
uniprot id: A0A2Y9GXA3
names: Subcellular Location Annotation
messages: Nucleus

29088:SV2C
gene id: 29088:SV2C
uniprot id: A0A2Y9HVJ1
uniprot id: A0A2Y9I2F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

29088:ENDOU
gene id: 29088:ENDOU
uniprot id: A0A2Y9I9A2
uniprot id: A0A8M1MC44
uniprot id: A0A8M1MFL1
uniprot id: A0A8M1MKI6
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

29088:NR5A1
gene id: 29088:NR5A1
uniprot id: A0A2Y9HCD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

29088:TATDN3
gene id: 29088:TATDN3
uniprot id: A0A2Y9GLF9
uniprot id: A0A8M1MEM3
uniprot id: A0A8M1MER1
uniprot id: A0A8M1MGS6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

29088:ACTL9
gene id: 29088:ACTL9
uniprot id: A0A2Y9IB09
names: Similarity
messages: Belongs to the actin family.

29088:MTX3
gene id: 29088:MTX3
uniprot id: A0A2Y9HVC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

29088:TACC3
gene id: 29088:TACC3
uniprot id: A0A2Y9G2L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

29088:NRCAM
gene id: 29088:NRCAM
uniprot id: A0A2Y9GHH1
uniprot id: A0A2Y9GHI5
uniprot id: A0A2Y9GHM1
uniprot id: A0A2Y9GKT6
uniprot id: A0A8M1MQ44
uniprot id: A0A8M1MQ49
uniprot id: A0A8M1MQ51
uniprot id: A0A8M1MQ54
uniprot id: A0A8M1MQ56
uniprot id: A0A8M1MQ59
uniprot id: A0A8M1MQ60
uniprot id: A0A8M1MQ65
uniprot id: A0A8M1MS04
uniprot id: A0A8M1MS09
uniprot id: A0A8M1MS21
uniprot id: A0A8M1MTD7
uniprot id: A0A8M1MTE3
uniprot id: A0A8M1MTE7
uniprot id: A0A8M1MTF0
uniprot id: A0A8M1MY82
uniprot id: A0A8M1MY84
uniprot id: A0A8M1MY85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

29088:TM2D1
gene id: 29088:TM2D1
uniprot id: A0A2Y9G9J2
uniprot id: A0A2Y9GC16
names: Subcellular Location Annotation
messages: Membrane

29088:VPS16
gene id: 29088:VPS16
uniprot id: A0A2Y9GZI3
uniprot id: A0A2Y9H5X6
uniprot id: A0A8M1MN27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS16 family.
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: Vesicle

29088:STMN2
gene id: 29088:STMN2
uniprot id: A0A2Y9GXC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the stathmin family.
messages: Cytoplasm
messages: Membrane
messages: lamellipodium

29088:UCHL5
gene id: 29088:UCHL5
uniprot id: A0A2Y9GSL5
uniprot id: A0A2Y9GWU4
uniprot id: A0A2Y9GYF3
names: Similarity
messages: Belongs to the peptidase C12 family.

29088:LOC110582408
gene id: 29088:LOC110582408
uniprot id: A0A2Y9HFK3
names: Similarity
messages: Belongs to the HTATSF1 family.

29088:LOC110576997
gene id: 29088:LOC110576997
uniprot id: A0A2Y9GRP5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:SELENOI
gene id: 29088:SELENOI
uniprot id: A0A2Y9HT80
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

29088:GBA
gene id: 29088:GBA
uniprot id: A0A2Y9GIK7
uniprot id: A0A2Y9GK33
uniprot id: A0A8M1MDA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 30 family.
messages: Lysosome membrane

29088:LOC110573343
gene id: 29088:LOC110573343
uniprot id: A0A2Y9GEP1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:GPATCH1
gene id: 29088:GPATCH1
uniprot id: A0A2Y9I4W6
names: Similarity
messages: Belongs to the GPATCH1 family.

29088:KHDC4
gene id: 29088:KHDC4
uniprot id: A0A2Y9GF00
uniprot id: A0A2Y9GF02
names: Similarity
messages: Belongs to the KHDC4 family.

29088:DKK4
gene id: 29088:DKK4
uniprot id: A0A2Y9GDQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

29088:ACSF2
gene id: 29088:ACSF2
uniprot id: A0A2Y9I892
uniprot id: A0A2Y9I8Z7
uniprot id: A0A2Y9IFN7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

29088:MFN2
gene id: 29088:MFN2
uniprot id: A0A2Y9GKN5
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

29088:LOC110571190
gene id: 29088:LOC110571190
uniprot id: A0A8M1M3U5
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

29088:PIGS
gene id: 29088:PIGS
uniprot id: A0A2Y9IBQ6
uniprot id: A0A2Y9IEE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:LOC110591488
gene id: 29088:LOC110591488
uniprot id: A0A2Y9I2U0
names: Subcellular Location Annotation
messages: Secreted

29088:MED22
gene id: 29088:MED22
uniprot id: A0A2Y9H6S5
names: Function
names: Subcellular Location Annotation
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

29088:HCST
gene id: 29088:HCST
uniprot id: A0A2Y9HY46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAP10 family.
messages: Membrane

29088:CAPN10
gene id: 29088:CAPN10
uniprot id: A0A2Y9GA61
names: Similarity
messages: Belongs to the peptidase C2 family.

29088:SCNN1A
gene id: 29088:SCNN1A
uniprot id: A0A2Y9H4B6
names: Subcellular Location Annotation
messages: Membrane

29088:GPKOW
gene id: 29088:GPKOW
uniprot id: A0A8M1M5C1
uniprot id: A0A8M1M935
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOS2 family.
messages: Nucleus

29088:BATF
gene id: 29088:BATF
uniprot id: A0A2Y9GAW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

29088:PFN4
gene id: 29088:PFN4
uniprot id: A0A2Y9HVP0
names: Similarity
messages: Belongs to the profilin family.

29088:LOC110590161
gene id: 29088:LOC110590161
uniprot id: A0A2Y9HYE0
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

29088:SF3A1
gene id: 29088:SF3A1
uniprot id: A0A2Y9IAK0
names: Subcellular Location Annotation
messages: Nucleus

29088:HNRNPA2B1
gene id: 29088:HNRNPA2B1
uniprot id: A0A2Y9H1P6
uniprot id: A0A2Y9H1R6
names: Subcellular Location Annotation
messages: Cytoplasmic granule
messages: extracellular exosome

29088:AOPEP
gene id: 29088:AOPEP
uniprot id: A0A2Y9G3I5
names: Similarity
messages: Belongs to the peptidase M1 family.

29088:SCARB1
gene id: 29088:SCARB1
uniprot id: A0A8M1MUZ4
names: Similarity
messages: Belongs to the CD36 family.

29088:LEUTX
gene id: 29088:LEUTX
uniprot id: A0A2Y9HY61
names: Subcellular Location Annotation
messages: Nucleus

29088:SUCNR1
gene id: 29088:SUCNR1
uniprot id: A0A2Y9GUV1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:CREB3L4
gene id: 29088:CREB3L4
uniprot id: A0A2Y9GF45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:TRPM1
gene id: 29088:TRPM1
uniprot id: A0A8M1MM73
names: Subcellular Location Annotation
messages: Membrane

29088:B9D1
gene id: 29088:B9D1
uniprot id: A0A2Y9HLR1
names: Subcellular Location Annotation
messages: cilium basal body

29088:SOGA3
gene id: 29088:SOGA3
uniprot id: A0A2Y9HIC1
uniprot id: A0A8M1ML75
names: Similarity
messages: Belongs to the SOGA family.

29088:FANCC
gene id: 29088:FANCC
uniprot id: A0A8M1MRR0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. This complex may also include HSP70.
messages: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
messages: Nucleus

29088:ZCCHC17
gene id: 29088:ZCCHC17
uniprot id: A0A2Y9GKV8
uniprot id: A0A2Y9GRA5
uniprot id: A0A8M1M948
names: Subcellular Location Annotation
messages: nucleolus

29088:CDH3
gene id: 29088:CDH3
uniprot id: A0A2Y9ICH8
uniprot id: A0A8M1MW29
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

29088:GFRA1
gene id: 29088:GFRA1
uniprot id: A0A8M1MFD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane

29088:SDE2
gene id: 29088:SDE2
uniprot id: A0A2Y9G851
uniprot id: A0A2Y9G892
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDE2 family.
messages: Nucleus

29088:GSPT1
gene id: 29088:GSPT1
uniprot id: A0A2Y9HQY0
uniprot id: A0A2Y9HXD8
uniprot id: A0A8M1MCM5
uniprot id: A0A8M1MEQ8
uniprot id: A0A8M1MG41
uniprot id: A0A8M1ML32
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

29088:IRF9
gene id: 29088:IRF9
uniprot id: A0A2Y9HPP0
uniprot id: A0A8M1MKE9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

29088:PRICKLE1
gene id: 29088:PRICKLE1
uniprot id: A0A8M1MIU4
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

29088:TPT1
gene id: 29088:TPT1
uniprot id: A0A2Y9HUL4
uniprot id: A0A8M1MAD1
names: Similarity
messages: Belongs to the TCTP family.

29088:LOC110578137
gene id: 29088:LOC110578137
uniprot id: A0A2Y9GVV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

29088:OAZ1
gene id: 29088:OAZ1
uniprot id: A0A2Y9IAJ9
names: Similarity
messages: Belongs to the ODC antizyme family.

29088:ATRNL1
gene id: 29088:ATRNL1
uniprot id: A0A2Y9HZU4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SKA1
gene id: 29088:SKA1
uniprot id: A0A2Y9GXL8
names: Similarity
messages: Belongs to the SKA1 family.

29088:KCNJ14
gene id: 29088:KCNJ14
uniprot id: A0A2Y9GD19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

29088:LOC110581698
gene id: 29088:LOC110581698
uniprot id: A0A8M1MR67
names: Similarity
messages: Belongs to the paralemmin family.

29088:SLC25A38
gene id: 29088:SLC25A38
uniprot id: A0A2Y9IJJ7
uniprot id: A0A8M1MM18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.
messages: Mitochondrion inner membrane
messages: Plays a role as pro-apoptotic protein that induces caspase-dependent apoptosis.

29088:GCN1
gene id: 29088:GCN1
uniprot id: A0A8M1MTH8
uniprot id: A0A8M1MTI0
uniprot id: A0A8M1MVB4
uniprot id: A0A8M1MYX9
names: Similarity
messages: Belongs to the GCN1 family.

29088:SERPINE3
gene id: 29088:SERPINE3
uniprot id: A0A2Y9G4C5
names: Similarity
messages: Belongs to the serpin family.

29088:LOC110590308
gene id: 29088:LOC110590308
uniprot id: A0A2Y9HYJ0
uniprot id: A0A2Y9HYN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

29088:DPPA5
gene id: 29088:DPPA5
uniprot id: A0A2Y9HIQ5
names: Similarity
messages: Belongs to the KHDC1 family.

29088:NFYA
gene id: 29088:NFYA
uniprot id: A0A2Y9H7P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

29088:IL24
gene id: 29088:IL24
uniprot id: A0A2Y9GKL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

29088:STK17B
gene id: 29088:STK17B
uniprot id: A0A2Y9I3B8
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:SDHC
gene id: 29088:SDHC
uniprot id: A0A2Y9GIB2
uniprot id: A0A8M1MGV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: The heme is bound between the two transmembrane subunits.

29088:SPTA1
gene id: 29088:SPTA1
uniprot id: A0A2Y9GEW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spectrin family.
messages: cell cortex
messages: cytoskeleton

29088:TBK1
gene id: 29088:TBK1
uniprot id: A0A2Y9G5J8
uniprot id: A0A8M1MA90
names: Subcellular Location Annotation
messages: Cytoplasm

29088:PPDPF
gene id: 29088:PPDPF
uniprot id: A0A8M1MLQ8
names: Similarity
messages: Belongs to the PPDPF family.

29088:GLB1L
gene id: 29088:GLB1L
uniprot id: A0A2Y9I3M2
uniprot id: A0A2Y9I476
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

29088:IST1
gene id: 29088:IST1
uniprot id: A0A2Y9IBL9
uniprot id: A0A2Y9ICF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IST1 family.
messages: Cytoplasmic vesicle
messages: Nucleus envelope

29088:PRDM1
gene id: 29088:PRDM1
uniprot id: A0A2Y9HAN8
uniprot id: A0A2Y9HGR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

29088:RPRD2
gene id: 29088:RPRD2
uniprot id: A0A2Y9H375
uniprot id: A0A8M1M8H9
uniprot id: A0A8M1M8I2
uniprot id: A0A8M1MAN6
uniprot id: A0A8M1MC16
uniprot id: A0A8M1MGL6
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

29088:LOC110570047
gene id: 29088:LOC110570047
uniprot id: A0A2Y9G3U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

29088:ARID5B
gene id: 29088:ARID5B
uniprot id: A0A2Y9HTW1
uniprot id: A0A2Y9HUE7
uniprot id: A0A8M1MDU0
names: Similarity
messages: Belongs to the ARID5B family.

29088:SEBOX
gene id: 29088:SEBOX
uniprot id: A0A2Y9I8B8
names: Subcellular Location Annotation
messages: Nucleus

29088:ATP5MC2
gene id: 29088:ATP5MC2
uniprot id: A0A2Y9GT56
uniprot id: A0A8M1MIM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

29088:TFAP2D
gene id: 29088:TFAP2D
uniprot id: A0A2Y9H7Z6
names: Similarity
messages: Belongs to the AP-2 family.

29088:ASPM
gene id: 29088:ASPM
uniprot id: A0A2Y9GJK9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:WDFY1
gene id: 29088:WDFY1
uniprot id: A0A2Y9GHM2
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

29088:BPIFC
gene id: 29088:BPIFC
uniprot id: A0A2Y9GV24
uniprot id: A0A2Y9H0U0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

29088:DNAH7
gene id: 29088:DNAH7
uniprot id: A0A2Y9I4P0
names: Similarity
messages: Belongs to the dynein heavy chain family.

29088:MYORG
gene id: 29088:MYORG
uniprot id: A0A2Y9HBS7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

29088:CAPN6
gene id: 29088:CAPN6
uniprot id: A0A8M1M1J4
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:HOOK3
gene id: 29088:HOOK3
uniprot id: A0A2Y9GE22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

29088:KMT2A
gene id: 29088:KMT2A
uniprot id: A0A2Y9HKQ1
uniprot id: A0A8M1MPC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
messages: Nucleus

29088:PCNA
gene id: 29088:PCNA
uniprot id: A0A2Y9GZP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

29088:MRTO4
gene id: 29088:MRTO4
uniprot id: A0A2Y9GKS6
uniprot id: A0A2Y9GPE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

29088:FGFR3
gene id: 29088:FGFR3
uniprot id: A0A8M1M542
uniprot id: A0A8M1M5E2
uniprot id: A0A8M1M5E7
uniprot id: A0A8M1M7I4
uniprot id: A0A8M1M8Z9
uniprot id: A0A8M1M905
uniprot id: A0A8M1MD70
uniprot id: A0A8M1MD76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

29088:LOC110589080
gene id: 29088:LOC110589080
uniprot id: A0A8M1MHX9
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.
messages: Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.

29088:CHI3L1
gene id: 29088:CHI3L1
uniprot id: A0A2Y9GST5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 18 family.
messages: Endoplasmic reticulum
messages: Monomer.
messages: extracellular space
messages: perinuclear region

29088:DHH
gene id: 29088:DHH
uniprot id: A0A2Y9IDV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

29088:CACNB3
gene id: 29088:CACNB3
uniprot id: A0A2Y9IA42
uniprot id: A0A2Y9IGP9
uniprot id: A0A8M1MA98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Cytoplasm

29088:VAC14
gene id: 29088:VAC14
uniprot id: A0A2Y9I924
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAC14 family.
messages: Endosome membrane
messages: Microsome membrane

29088:ST3GAL3
gene id: 29088:ST3GAL3
uniprot id: A0A2Y9GQ87
uniprot id: A0A8M1M7U4
uniprot id: A0A8M1M825
uniprot id: A0A8M1M829
uniprot id: A0A8M1MA87
uniprot id: A0A8M1MBL3
uniprot id: A0A8M1MBL8
uniprot id: A0A8M1MG53
uniprot id: A0A8M1MG58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

29088:PTPRK
gene id: 29088:PTPRK
uniprot id: A0A8M1MHY0
uniprot id: A0A8M1MK08
uniprot id: A0A8M1MLB5
uniprot id: A0A8M1MRW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

29088:JAG2
gene id: 29088:JAG2
uniprot id: A0A8M1MMS6
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

29088:NCEH1
gene id: 29088:NCEH1
uniprot id: A0A2Y9I3E8
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

29088:LOC110589223
gene id: 29088:LOC110589223
uniprot id: A0A2Y9HV11
uniprot id: A0A8M1MF24
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9.
messages: Membrane
messages: basement membrane

29088:IP6K1
gene id: 29088:IP6K1
uniprot id: A0A2Y9GTE9
uniprot id: A0A2Y9GTK0
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

29088:SKAP2
gene id: 29088:SKAP2
uniprot id: A0A2Y9H176
names: Similarity
messages: Belongs to the SKAP family.

29088:LSM14A
gene id: 29088:LSM14A
uniprot id: A0A2Y9HXP3
uniprot id: A0A2Y9HY06
uniprot id: A0A2Y9I2M4
uniprot id: A0A8M1M0K8
uniprot id: A0A8M1M0L3
uniprot id: A0A8M1M0W2
uniprot id: A0A8M1M0W8
uniprot id: A0A8M1M354
uniprot id: A0A8M1M4P1
uniprot id: A0A8M1M8C7
uniprot id: A0A8M1M8D2
names: Similarity
messages: Belongs to the LSM14 family.

29088:NDRG1
gene id: 29088:NDRG1
uniprot id: A0A2Y9GYR4
names: Similarity
messages: Belongs to the NDRG family.

29088:TIMM21
gene id: 29088:TIMM21
uniprot id: A0A2Y9GXS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane
messages: Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.

29088:SEPHS2
gene id: 29088:SEPHS2
uniprot id: A0A2Y9I1I0
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

29088:FIS1
gene id: 29088:FIS1
uniprot id: A0A2Y9HEQ7
uniprot id: A0A2Y9HXC5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIS1 family.
messages: Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.
messages: Membrane
messages: Mitochondrion outer membrane
messages: The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.

29088:PYY
gene id: 29088:PYY
uniprot id: A0A2Y9GH40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

29088:SLC25A27
gene id: 29088:SLC25A27
uniprot id: A0A2Y9HDE0
uniprot id: A0A2Y9HEK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:COG7
gene id: 29088:COG7
uniprot id: A0A2Y9GTC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG7 family.
messages: Golgi apparatus membrane
messages: Membrane

29088:CENPL
gene id: 29088:CENPL
uniprot id: A0A2Y9GGP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-L/IML3 family.
messages: Nucleus

29088:COPS7B
gene id: 29088:COPS7B
uniprot id: A0A2Y9H330
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

29088:LACTB2
gene id: 29088:LACTB2
uniprot id: A0A2Y9H2V2
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

29088:PHKA1
gene id: 29088:PHKA1
uniprot id: A0A8M1M0U4
uniprot id: A0A8M1M0V0
uniprot id: A0A8M1M151
uniprot id: A0A8M1M3D5
uniprot id: A0A8M1M4X5
uniprot id: A0A8M1M8L9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

29088:SEMA4F
gene id: 29088:SEMA4F
uniprot id: A0A2Y9HY43
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:GNG4
gene id: 29088:GNG4
uniprot id: A0A2Y9HJB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

29088:PSME3
gene id: 29088:PSME3
uniprot id: A0A2Y9GHJ8
uniprot id: A0A8M1MXQ2
uniprot id: A0A8M1MZA5
names: Similarity
messages: Belongs to the PA28 family.

29088:FAM135A
gene id: 29088:FAM135A
uniprot id: A0A2Y9H7A0
uniprot id: A0A2Y9HE53
uniprot id: A0A8M1MH68
names: Similarity
messages: Belongs to the FAM135 family.

29088:UBE2M
gene id: 29088:UBE2M
uniprot id: A0A2Y9HCT7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:SLC15A3
gene id: 29088:SLC15A3
uniprot id: A0A2Y9GTF6
uniprot id: A0A2Y9GV50
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

29088:SLAIN2
gene id: 29088:SLAIN2
uniprot id: A0A2Y9I057
uniprot id: A0A2Y9I4U7
uniprot id: A0A2Y9I6Q5
uniprot id: A0A8M1M8V2
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

29088:ATG2A
gene id: 29088:ATG2A
uniprot id: A0A8M1MNZ0
uniprot id: A0A8M1MNZ7
uniprot id: A0A8M1MQW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

29088:TSPAN32
gene id: 29088:TSPAN32
uniprot id: A0A2Y9GNW2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:CARMIL2
gene id: 29088:CARMIL2
uniprot id: A0A2Y9I6N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

29088:KDM5A
gene id: 29088:KDM5A
uniprot id: A0A2Y9HB07
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

29088:LOC110579188
gene id: 29088:LOC110579188
uniprot id: A0A2Y9GYI8
names: Similarity
messages: Belongs to the BEX family.

29088:ATF2
gene id: 29088:ATF2
uniprot id: A0A2Y9ICB7
uniprot id: A0A8M1M9S1
uniprot id: A0A8M1ME31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

29088:TMEM86A
gene id: 29088:TMEM86A
uniprot id: A0A2Y9GUI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

29088:ACSS2
gene id: 29088:ACSS2
uniprot id: A0A2Y9H5Y9
uniprot id: A0A8M1MPC2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

29088:LOC110581005
gene id: 29088:LOC110581005
uniprot id: A0A8M1ME64
names: Subcellular Location Annotation
messages: Nucleus

29088:NLN
gene id: 29088:NLN
uniprot id: A0A8M1MJ99
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

29088:CEBPB
gene id: 29088:CEBPB
uniprot id: A0A2Y9GQM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

29088:TMEM218
gene id: 29088:TMEM218
uniprot id: A0A2Y9HJI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM218 family.
messages: May be involved in ciliary biogenesis or function.
messages: Membrane
messages: cilium

29088:MDK
gene id: 29088:MDK
uniprot id: A0A2Y9GMH6
names: Similarity
messages: Belongs to the pleiotrophin family.

29088:HTR6
gene id: 29088:HTR6
uniprot id: A0A2Y9GJ60
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:ERO1B
gene id: 29088:ERO1B
uniprot id: A0A2Y9HQ08
uniprot id: A0A8M1MEW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

29088:LOC110589381
gene id: 29088:LOC110589381
uniprot id: A0A2Y9HVM6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

29088:TSHB
gene id: 29088:TSHB
uniprot id: A0A2Y9H9E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

29088:LOC110589287
gene id: 29088:LOC110589287
uniprot id: A0A2Y9I030
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

29088:TMEM63C
gene id: 29088:TMEM63C
uniprot id: A0A2Y9G8B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

29088:EGR1
gene id: 29088:EGR1
uniprot id: A0A2Y9I5B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

29088:PDIA2
gene id: 29088:PDIA2
uniprot id: A0A2Y9HVJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

29088:LOC110573740
gene id: 29088:LOC110573740
uniprot id: A0A2Y9GFY7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TCP11L1
gene id: 29088:TCP11L1
uniprot id: A0A2Y9GMD5
names: Similarity
messages: Belongs to the TCP11 family.

29088:TDO2
gene id: 29088:TDO2
uniprot id: A0A2Y9HX86
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:NEK6
gene id: 29088:NEK6
uniprot id: A0A8M1MSE0
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:HACD2
gene id: 29088:HACD2
uniprot id: A0A2Y9H967
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:SI
gene id: 29088:SI
uniprot id: A0A2Y9I2W7
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110588560
gene id: 29088:LOC110588560
uniprot id: A0A8M1MBS8
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.
messages: Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.

29088:CDC42
gene id: 29088:CDC42
uniprot id: A0A8M1M8Z5
uniprot id: A0A8M1MHE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.
messages: centrosome

29088:LOC110580494
gene id: 29088:LOC110580494
uniprot id: A0A8M1MBY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus

29088:MRPL41
gene id: 29088:MRPL41
uniprot id: A0A2Y9H4Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

29088:SLC4A5
gene id: 29088:SLC4A5
uniprot id: A0A8M1MLU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

29088:ADAMTS20
gene id: 29088:ADAMTS20
uniprot id: A0A2Y9I9E9
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:LOC110593638
gene id: 29088:LOC110593638
uniprot id: A0A2Y9IGP4
names: Subcellular Location Annotation
messages: Membrane

29088:SEC24A
gene id: 29088:SEC24A
uniprot id: A0A8M1MPK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

29088:F2RL3
gene id: 29088:F2RL3
uniprot id: A0A2Y9GLN3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:TUB
gene id: 29088:TUB
uniprot id: A0A2Y9GVX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

29088:ACOX1
gene id: 29088:ACOX1
uniprot id: A0A2Y9GC87
uniprot id: A0A2Y9GF62
uniprot id: A0A2Y9GGP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

29088:TAFA2
gene id: 29088:TAFA2
uniprot id: A0A2Y9G5S8
names: Similarity
messages: Belongs to the TAFA family.

29088:FMN1
gene id: 29088:FMN1
uniprot id: A0A2Y9HGY4
uniprot id: A0A2Y9HHA2
names: Similarity
messages: Belongs to the formin homology family. Cappuccino subfamily.

29088:MOCS1
gene id: 29088:MOCS1
uniprot id: A0A2Y9H7S5
uniprot id: A0A8M1MHG2
names: Similarity
messages: In the C-terminal section; belongs to the MoaC family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. MoaA family.

29088:PSME3IP1
gene id: 29088:PSME3IP1
uniprot id: A0A2Y9IC10
uniprot id: A0A2Y9IJE4
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110592328
gene id: 29088:LOC110592328
uniprot id: A0A8M1M949
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

29088:XDH
gene id: 29088:XDH
uniprot id: A0A2Y9HNS0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Homodimer. Interacts with BTN1A1.
messages: Peroxisome

29088:SLC1A2
gene id: 29088:SLC1A2
uniprot id: A0A2Y9GMQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

29088:CDCA2
gene id: 29088:CDCA2
uniprot id: A0A2Y9HSK4
names: Subcellular Location Annotation
messages: Nucleus

29088:MED11
gene id: 29088:MED11
uniprot id: A0A2Y9HF38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

29088:GLDN
gene id: 29088:GLDN
uniprot id: A0A2Y9HDG9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:HADHB
gene id: 29088:HADHB
uniprot id: A0A2Y9HN64
uniprot id: A0A2Y9HNM6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

29088:DPCD
gene id: 29088:DPCD
uniprot id: A0A2Y9HW92
uniprot id: A0A2Y9HWB9
uniprot id: A0A8M1ME30
uniprot id: A0A8M1MHJ0
names: Similarity
messages: Belongs to the DPCD family.

29088:LOC110569716
gene id: 29088:LOC110569716
uniprot id: A0A8M1M1C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

29088:DPAGT1
gene id: 29088:DPAGT1
uniprot id: A0A2Y9HK39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:OCIAD1
gene id: 29088:OCIAD1
uniprot id: A0A2Y9I076
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OCIAD1 family.
messages: Endosome
messages: Interacts with STAT3.
messages: Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes.
messages: The OCIA domain is necessary and sufficient for endosomal localization.

29088:LOC110587929
gene id: 29088:LOC110587929
uniprot id: A0A2Y9HVA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

29088:LOC110577876
gene id: 29088:LOC110577876
uniprot id: A0A2Y9GYW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:TMEM94
gene id: 29088:TMEM94
uniprot id: A0A8M1MZ58
names: Subcellular Location Annotation
messages: Membrane

29088:RAD51
gene id: 29088:RAD51
uniprot id: A0A2Y9HHJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Also involved in interstrand cross-link repair.

29088:ANXA7
gene id: 29088:ANXA7
uniprot id: A0A2Y9HUK4
uniprot id: A0A8M1MMF6
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

29088:RBBP5
gene id: 29088:RBBP5
uniprot id: A0A8M1MEK5
names: Subcellular Location Annotation
messages: Nucleus

29088:IARS2
gene id: 29088:IARS2
uniprot id: A0A8M1MDE6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

29088:NOG
gene id: 29088:NOG
uniprot id: A0A2Y9ICP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.
messages: Secreted

29088:UTP6
gene id: 29088:UTP6
uniprot id: A0A2Y9I7L6
names: Similarity
messages: Belongs to the UTP6 family.

29088:BET1
gene id: 29088:BET1
uniprot id: A0A2Y9H7G6
names: Subcellular Location Annotation
messages: Membrane

29088:SLC6A14
gene id: 29088:SLC6A14
uniprot id: A0A2Y9GXP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

29088:SNAPC3
gene id: 29088:SNAPC3
uniprot id: A0A2Y9GG69
uniprot id: A0A8M1MTI4
uniprot id: A0A8M1MUV6
uniprot id: A0A8M1MYJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAPC3/SRD2 family.
messages: Nucleus
messages: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1.
messages: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

29088:MED13L
gene id: 29088:MED13L
uniprot id: A0A8M1MUV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

29088:EDA
gene id: 29088:EDA
uniprot id: A0A2Y9GA48
uniprot id: A0A2Y9GCQ1
uniprot id: A0A2Y9GCT6
uniprot id: A0A2Y9GDT6
uniprot id: A0A2Y9GDW2
uniprot id: A0A2Y9GDX3
uniprot id: A0A8M1M146
uniprot id: A0A8M1M3C8
uniprot id: A0A8M1M4X0
uniprot id: A0A8M1M8L4
names: Similarity
messages: Belongs to the tumor necrosis factor family.

29088:SMIM7
gene id: 29088:SMIM7
uniprot id: A0A2Y9GNB8
names: Similarity
messages: Belongs to the SMIM7 family.

29088:LOC110582333
gene id: 29088:LOC110582333
uniprot id: A0A2Y9H8J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:AMD1
gene id: 29088:AMD1
uniprot id: A0A2Y9HH87
uniprot id: A0A8M1MHK0
uniprot id: A0A8M1MJN0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
messages: Heterotetramer of two alpha and two beta chains.

29088:LOC110574511
gene id: 29088:LOC110574511
uniprot id: A0A2Y9GNI0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:PPP2R5C
gene id: 29088:PPP2R5C
uniprot id: A0A2Y9G964
uniprot id: A0A2Y9GBQ3
uniprot id: A0A2Y9GCQ4
uniprot id: A0A8M1MJY1
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

29088:PNPLA7
gene id: 29088:PNPLA7
uniprot id: A0A2Y9H530
uniprot id: A0A2Y9H544
uniprot id: A0A2Y9H546
uniprot id: A0A2Y9HAH4
uniprot id: A0A2Y9HBU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:SLC8A3
gene id: 29088:SLC8A3
uniprot id: A0A2Y9G836
uniprot id: A0A2Y9G8A6
uniprot id: A0A2Y9G8F2
uniprot id: A0A2Y9GAS6
uniprot id: A0A2Y9GBR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

29088:LRRC8A
gene id: 29088:LRRC8A
uniprot id: A0A2Y9HD03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

29088:NFIL3
gene id: 29088:NFIL3
uniprot id: A0A2Y9HKH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock. Protects pro-B cells from programmed cell death.
messages: Belongs to the bZIP family. NFIL3 subfamily.
messages: Homodimer. Binds DNA as a dimer.
messages: Nucleus

29088:S100G
gene id: 29088:S100G
uniprot id: A0A2Y9GGH8
names: Similarity
messages: Belongs to the S-100 family.

29088:LAMA1
gene id: 29088:LAMA1
uniprot id: A0A2Y9GRL5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

29088:TFB1M
gene id: 29088:TFB1M
uniprot id: A0A2Y9HBL2
uniprot id: A0A2Y9HHQ3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Interacts with mitochondrial RNA polymerase POLRMT. Interacts with TFAM.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity.

29088:FOXJ2
gene id: 29088:FOXJ2
uniprot id: A0A2Y9H3W1
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC123325305
gene id: 29088:LOC123325305
uniprot id: A0A8M1MGM7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:DST
gene id: 29088:DST
uniprot id: A0A8M1MLL3
names: Subcellular Location Annotation
messages: cytoskeleton

29088:KIF27
gene id: 29088:KIF27
uniprot id: A0A2Y9G3J3
uniprot id: A0A8M1MR54
uniprot id: A0A8M1MR62
uniprot id: A0A8M1MUD9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:ATP2C1
gene id: 29088:ATP2C1
uniprot id: A0A8M1MT76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Golgi stack membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer. Homodimer.
messages: trans-Golgi network membrane

29088:LOC110569927
gene id: 29088:LOC110569927
uniprot id: A0A8M1MV08
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

29088:MLH3
gene id: 29088:MLH3
uniprot id: A0A2Y9G8I8
uniprot id: A0A8M1MJ75
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

29088:LOC110572638
gene id: 29088:LOC110572638
uniprot id: A0A2Y9GCI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

29088:LRP3
gene id: 29088:LRP3
uniprot id: A0A2Y9I384
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC123324340
gene id: 29088:LOC123324340
uniprot id: A0A8M1M9L5
names: Similarity
messages: Belongs to the LRRFIP family.

29088:CDADC1
gene id: 29088:CDADC1
uniprot id: A0A2Y9H0S1
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

29088:FAM171A1
gene id: 29088:FAM171A1
uniprot id: A0A8M1MAX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

29088:ANKH
gene id: 29088:ANKH
uniprot id: A0A2Y9I346
uniprot id: A0A2Y9I9M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

29088:OSBPL2
gene id: 29088:OSBPL2
uniprot id: A0A2Y9G3D4
names: Similarity
messages: Belongs to the OSBP family.

29088:TBX1
gene id: 29088:TBX1
uniprot id: A0A8M1MYT9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

29088:DEFB127
gene id: 29088:DEFB127
uniprot id: A0A2Y9H003
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

29088:SKI
gene id: 29088:SKI
uniprot id: A0A8M1MB31
names: Similarity
messages: Belongs to the SKI family.

29088:SNU13
gene id: 29088:SNU13
uniprot id: A0A2Y9H042
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

29088:DDX6
gene id: 29088:DDX6
uniprot id: A0A2Y9HJG4
uniprot id: A0A2Y9HJU4
names: Similarity
messages: Belongs to the DEAD box helicase family.

29088:PYM1
gene id: 29088:PYM1
uniprot id: A0A2Y9GYN0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pym family.
messages: Cytoplasm
messages: Interacts (via N-terminus) with magoh and rbm8a; the interaction is direct. Associates (eIF2A-like region) with the 40S ribosomal subunit and the 48S preinitiation complex.

29088:SMAD4
gene id: 29088:SMAD4
uniprot id: A0A2Y9GS17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

29088:LOC110591078
gene id: 29088:LOC110591078
uniprot id: A0A8M1MG79
names: Similarity
messages: Belongs to the NAC-beta family.

29088:THOC7
gene id: 29088:THOC7
uniprot id: A0A2Y9HM86
uniprot id: A0A2Y9HME7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

29088:MYOC
gene id: 29088:MYOC
uniprot id: A0A2Y9GJZ8
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion intermembrane space
messages: Mitochondrion outer membrane
messages: Rough endoplasmic reticulum
messages: cilium
messages: extracellular exosome
messages: extracellular matrix

29088:ST7L
gene id: 29088:ST7L
uniprot id: A0A2Y9H8Y5
uniprot id: A0A8M1M9H4
uniprot id: A0A8M1MBU9
uniprot id: A0A8M1MHX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

29088:LOC110587153
gene id: 29088:LOC110587153
uniprot id: A0A8M1MG71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

29088:FAM120B
gene id: 29088:FAM120B
uniprot id: A0A2Y9HBE0
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

29088:GABRB1
gene id: 29088:GABRB1
uniprot id: A0A2Y9I019
uniprot id: A0A2Y9I0J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:SLC35A1
gene id: 29088:SLC35A1
uniprot id: A0A2Y9HAW8
uniprot id: A0A8M1MKV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

29088:CHRNA9
gene id: 29088:CHRNA9
uniprot id: A0A2Y9I048
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:PPP1R14D
gene id: 29088:PPP1R14D
uniprot id: A0A2Y9HPL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Inhibitor of PPP1CA.
messages: Membrane

29088:LOC110571914
gene id: 29088:LOC110571914
uniprot id: A0A8M1M9M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Cell projection
messages: Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Interacts with SHANK3; the interaction probably mediates the association of SHANK3 with the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton
messages: synaptosome

29088:NTAQ1
gene id: 29088:NTAQ1
uniprot id: A0A2Y9H262
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NTAQ1 family.
messages: Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
messages: Monomer.

29088:LOC110585442
gene id: 29088:LOC110585442
uniprot id: A0A2Y9HI31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110591776
gene id: 29088:LOC110591776
uniprot id: A0A8M1M266
uniprot id: A0A8M1M4P7
uniprot id: A0A8M1M679
uniprot id: A0A8M1MA26
names: Subcellular Location Annotation
messages: Nucleus

29088:NUP35
gene id: 29088:NUP35
uniprot id: A0A2Y9I3X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nup35 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

29088:TMED9
gene id: 29088:TMED9
uniprot id: A0A2Y9I762
uniprot id: A0A8M1MH08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:PEPD
gene id: 29088:PEPD
uniprot id: A0A2Y9I4E4
uniprot id: A0A8M1M0N5
uniprot id: A0A8M1M378
names: Similarity
messages: Belongs to the peptidase M24B family.

29088:LOC110586953
gene id: 29088:LOC110586953
uniprot id: A0A2Y9HSX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:RAE1
gene id: 29088:RAE1
uniprot id: A0A2Y9G5N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat rae1 family.
messages: spindle pole

29088:LOC110587190
gene id: 29088:LOC110587190
uniprot id: A0A8M1MKS8
uniprot id: A0A8M1MP43
names: Similarity
messages: Belongs to the NAC-beta family.

29088:CCL1
gene id: 29088:CCL1
uniprot id: A0A2Y9ICT9
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

29088:CA3
gene id: 29088:CA3
uniprot id: A0A2Y9GX28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Cytoplasm
messages: Reversible hydration of carbon dioxide.

29088:FAM120C
gene id: 29088:FAM120C
uniprot id: A0A2Y9I760
uniprot id: A0A2Y9IE09
uniprot id: A0A8M1M578
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

29088:PAGE4
gene id: 29088:PAGE4
uniprot id: A0A2Y9G7L4
names: Similarity
messages: Belongs to the GAGE family.

29088:TM2D2
gene id: 29088:TM2D2
uniprot id: A0A2Y9GDZ1
uniprot id: A0A2Y9GE13
names: Subcellular Location Annotation
messages: Membrane

29088:ARPC3
gene id: 29088:ARPC3
uniprot id: A0A2Y9H082
uniprot id: A0A8M1MYU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

29088:OAZ3
gene id: 29088:OAZ3
uniprot id: A0A2Y9GWI5
names: Similarity
messages: Belongs to the ODC antizyme family.

29088:RPA3
gene id: 29088:RPA3
uniprot id: A0A2Y9H1I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

29088:MOG
gene id: 29088:MOG
uniprot id: A0A2Y9HMG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Homodimer.
messages: Membrane
messages: Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion.

29088:EXOC7
gene id: 29088:EXOC7
uniprot id: A0A2Y9GBY8
uniprot id: A0A2Y9GEL8
uniprot id: A0A2Y9GG84
uniprot id: A0A8M1MV09
uniprot id: A0A8M1MWR1
uniprot id: A0A8M1MXJ3
uniprot id: A0A8M1MZ85
names: Function
names: Similarity
messages: Belongs to the EXO70 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

29088:GABRB3
gene id: 29088:GABRB3
uniprot id: A0A2Y9GDL2
uniprot id: A0A2Y9GF34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:AGRN
gene id: 29088:AGRN
uniprot id: A0A2Y9GKD1
uniprot id: A0A2Y9GKG6
uniprot id: A0A2Y9GKH1
uniprot id: A0A2Y9GKM5
uniprot id: A0A2Y9GQQ4
uniprot id: A0A8M1M8U9
uniprot id: A0A8M1MB88
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110589307
gene id: 29088:LOC110589307
uniprot id: A0A2Y9HUV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

29088:TDGF1
gene id: 29088:TDGF1
uniprot id: A0A2Y9GZW7
names: Caution
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ZC3H15
gene id: 29088:ZC3H15
uniprot id: A0A2Y9I532
uniprot id: A0A2Y9I586
uniprot id: A0A2Y9I5T0
uniprot id: A0A8M1M698
names: Similarity
messages: Belongs to the ZC3H15/TMA46 family.

29088:LOC110576478
gene id: 29088:LOC110576478
uniprot id: A0A2Y9GPX1
names: Subcellular Location Annotation
messages: Membrane

29088:STX4
gene id: 29088:STX4
uniprot id: A0A2Y9I3Q1
names: Similarity
messages: Belongs to the syntaxin family.

29088:SPPL2C
gene id: 29088:SPPL2C
uniprot id: A0A2Y9G8F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

29088:MEIS3
gene id: 29088:MEIS3
uniprot id: A0A2Y9GHA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

29088:FAM171B
gene id: 29088:FAM171B
uniprot id: A0A2Y9I9D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

29088:VPS35L
gene id: 29088:VPS35L
uniprot id: A0A2Y9HWJ2
uniprot id: A0A8M1MCJ4
uniprot id: A0A8M1MCP3
uniprot id: A0A8M1MG61
uniprot id: A0A8M1ML55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS35L family.
messages: Endosome

29088:FOXG1
gene id: 29088:FOXG1
uniprot id: A0A2Y9HHW5
names: Subcellular Location Annotation
messages: Nucleus

29088:ANO1
gene id: 29088:ANO1
uniprot id: A0A2Y9GPQ2
uniprot id: A0A2Y9GPY2
uniprot id: A0A2Y9GQ23
uniprot id: A0A2Y9GTS6
uniprot id: A0A2Y9GVJ8
uniprot id: A0A8M1MMT0
uniprot id: A0A8M1MMT2
uniprot id: A0A8M1MPS1
uniprot id: A0A8M1MR46
uniprot id: A0A8M1MWY8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:CNNM2
gene id: 29088:CNNM2
uniprot id: A0A2Y9HU20
uniprot id: A0A2Y9HUJ9
uniprot id: A0A2Y9HUK2
uniprot id: A0A2Y9HZE7
uniprot id: A0A2Y9I0X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

29088:IL1RN
gene id: 29088:IL1RN
uniprot id: A0A2Y9HP05
uniprot id: A0A2Y9HUB5
uniprot id: A0A2Y9HVT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
messages: Belongs to the IL-1 family.
messages: Secreted

29088:ATP6V1E2
gene id: 29088:ATP6V1E2
uniprot id: A0A2Y9HZ51
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

29088:USH2A
gene id: 29088:USH2A
uniprot id: A0A2Y9HQT6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:PFKFB1
gene id: 29088:PFKFB1
uniprot id: A0A2Y9HWM3
uniprot id: A0A2Y9I127
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

29088:REEP6
gene id: 29088:REEP6
uniprot id: A0A2Y9IF58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

29088:LOC110571920
gene id: 29088:LOC110571920
uniprot id: A0A2Y9G9Y1
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

29088:LOC110579906
gene id: 29088:LOC110579906
uniprot id: A0A2Y9H0U8
names: Similarity
messages: Belongs to the NDK family.

29088:AKAP8
gene id: 29088:AKAP8
uniprot id: A0A2Y9GIJ3
uniprot id: A0A2Y9GIR2
names: Similarity
messages: Belongs to the AKAP95 family.

29088:GRIN3B
gene id: 29088:GRIN3B
uniprot id: A0A8M1M5S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

29088:IL11RA
gene id: 29088:IL11RA
uniprot id: A0A2Y9H5E4
uniprot id: A0A2Y9HAS0
uniprot id: A0A8M1MYF9
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 3 subfamily.

29088:PRDM13
gene id: 29088:PRDM13
uniprot id: A0A2Y9HI27
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110589741
gene id: 29088:LOC110589741
uniprot id: A0A8M1MCW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

29088:ELOVL4
gene id: 29088:ELOVL4
uniprot id: A0A2Y9HH88
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL4 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May play a critical role in early brain and skin development.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Oligomer.
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

29088:LHCGR
gene id: 29088:LHCGR
uniprot id: A0A2Y9I3U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

29088:CACNB2
gene id: 29088:CACNB2
uniprot id: A0A2Y9HL66
uniprot id: A0A2Y9HL98
uniprot id: A0A2Y9HLD8
uniprot id: A0A2Y9HRT5
uniprot id: A0A2Y9HSU6
uniprot id: A0A2Y9HSV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
messages: sarcolemma

29088:LOC110585276
gene id: 29088:LOC110585276
uniprot id: A0A8M1MMY8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

29088:TBCE
gene id: 29088:TBCE
uniprot id: A0A2Y9HJL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

29088:LOC110593241
gene id: 29088:LOC110593241
uniprot id: A0A8M1MWR7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

29088:NXPH3
gene id: 29088:NXPH3
uniprot id: A0A2Y9I7W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

29088:BAAT
gene id: 29088:BAAT
uniprot id: A0A2Y9H6P5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

29088:CLTCL1
gene id: 29088:CLTCL1
uniprot id: A0A2Y9H4J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

29088:TTC27
gene id: 29088:TTC27
uniprot id: A0A2Y9HTD2
names: Similarity
messages: Belongs to the TTC27 family.

29088:POLR2M
gene id: 29088:POLR2M
uniprot id: A0A2Y9HDA0
uniprot id: A0A8M1MNE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRINL1 family.
messages: Nucleus

29088:ATP10B
gene id: 29088:ATP10B
uniprot id: A0A8M1MQQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

29088:LOC110585450
gene id: 29088:LOC110585450
uniprot id: A0A2Y9HHQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:E2F1
gene id: 29088:E2F1
uniprot id: A0A2Y9H6R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

29088:FEN1
gene id: 29088:FEN1
uniprot id: A0A2Y9GV70
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated by EP300. Acetylation inhibits both endonuclease and exonuclease activity. Acetylation also reduces DNA-binding activity but does not affect interaction with PCNA or EP300.
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity. The C-terminal domain binds EP300. Can bind simultaneously to both PCNA and EP300. Interacts with DDX11.
messages: Methylation at Arg-192 by PRMT5 impedes Ser-187 phosphorylation and increases interaction with PCNA.
messages: Mitochondrion
messages: Phosphorylation upon DNA damage induces relocalization to the nuclear plasma. Phosphorylation at Ser-187 by CDK2 occurs during late S-phase and results in dissociation from PCNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

29088:LOC110581174
gene id: 29088:LOC110581174
uniprot id: A0A2Y9H4P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:FBP1
gene id: 29088:FBP1
uniprot id: A0A2Y9G5Z4
uniprot id: A0A8M1MYP0
names: Similarity
messages: Belongs to the FBPase class 1 family.

29088:LOC110584449
gene id: 29088:LOC110584449
uniprot id: A0A2Y9HL05
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:KRT7
gene id: 29088:KRT7
uniprot id: A0A2Y9IGR3
names: Similarity
messages: Belongs to the intermediate filament family.

29088:PPP4C
gene id: 29088:PPP4C
uniprot id: A0A2Y9HWQ8
uniprot id: A0A2Y9I334
names: Similarity
messages: Belongs to the PPP phosphatase family.

29088:LOC110575788
gene id: 29088:LOC110575788
uniprot id: A0A2Y9GML1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:AHDC1
gene id: 29088:AHDC1
uniprot id: A0A2Y9GKY6
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110575720
gene id: 29088:LOC110575720
uniprot id: A0A8M1MQ06
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

29088:PRKX
gene id: 29088:PRKX
uniprot id: A0A2Y9GEY4
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:LOC123323427
gene id: 29088:LOC123323427
uniprot id: A0A2Y9HWD6
uniprot id: A0A8M1M2C9
names: Similarity
messages: Belongs to the NAC-beta family.

29088:TNC
gene id: 29088:TNC
uniprot id: A0A2Y9HAR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

29088:TMC8
gene id: 29088:TMC8
uniprot id: A0A8M1MUR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

29088:KLHL40
gene id: 29088:KLHL40
uniprot id: A0A2Y9G8N1
names: Similarity
names: Subcellular Location Annotation
messages: A band
messages: Belongs to the KLHL40 family.
messages: I band

29088:P4HA1
gene id: 29088:P4HA1
uniprot id: A0A2Y9HVV9
uniprot id: A0A2Y9HWG0
uniprot id: A0A2Y9I142
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

29088:LOC110576852
gene id: 29088:LOC110576852
uniprot id: A0A8M1MVH3
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

29088:LOC110573277
gene id: 29088:LOC110573277
uniprot id: A0A8M1MZ77
names: Similarity
messages: Belongs to the intermediate filament family.

29088:LOC110577114
gene id: 29088:LOC110577114
uniprot id: A0A2Y9GS52
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

29088:LOC110577470
gene id: 29088:LOC110577470
uniprot id: A0A2Y9GT81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:C3H2orf76
gene id: 29088:C3H2orf76
uniprot id: A0A2Y9HIF1
uniprot id: A0A2Y9HIT5
uniprot id: A0A2Y9HIU0
names: Similarity
messages: Belongs to the UPF0538 family.

29088:NEUROD4
gene id: 29088:NEUROD4
uniprot id: A0A2Y9GZ17
names: Subcellular Location Annotation
messages: Nucleus

29088:SPEM2
gene id: 29088:SPEM2
uniprot id: A0A2Y9HFI0
names: Subcellular Location Annotation
messages: Membrane

29088:MFSD4B
gene id: 29088:MFSD4B
uniprot id: A0A2Y9HHZ3
names: Subcellular Location Annotation
messages: Membrane

29088:PPP3CB
gene id: 29088:PPP3CB
uniprot id: A0A2Y9HW28
uniprot id: A0A2Y9HWI8
uniprot id: A0A2Y9HWJ3
uniprot id: A0A2Y9HWL9
uniprot id: A0A2Y9I197
uniprot id: A0A2Y9I1A0
uniprot id: A0A2Y9I2Z1
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

29088:SOAT2
gene id: 29088:SOAT2
uniprot id: A0A2Y9GYX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:NFKB1
gene id: 29088:NFKB1
uniprot id: A0A2Y9GAP8
uniprot id: A0A2Y9GAS7
uniprot id: A0A2Y9GAU7
uniprot id: A0A2Y9GAV1
uniprot id: A0A2Y9GDF5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:MBTPS1
gene id: 29088:MBTPS1
uniprot id: A0A8M1MXE0
names: Similarity
messages: Belongs to the peptidase S8 family.

29088:TLE6
gene id: 29088:TLE6
uniprot id: A0A2Y9IB79
names: Similarity
messages: Belongs to the WD repeat Groucho/TLE family.

29088:UNK
gene id: 29088:UNK
uniprot id: A0A8M1MVI1
uniprot id: A0A8M1MX25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

29088:LOC110572112
gene id: 29088:LOC110572112
uniprot id: A0A2Y9GEP0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

29088:LOC110576783
gene id: 29088:LOC110576783
uniprot id: A0A2Y9GUY1
uniprot id: A0A2Y9GWK9
names: Similarity
messages: Belongs to the multicopper oxidase family.

29088:PLCG1
gene id: 29088:PLCG1
uniprot id: A0A2Y9GZB7
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

29088:LOC110580249
gene id: 29088:LOC110580249
uniprot id: A0A2Y9H8H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110573969
gene id: 29088:LOC110573969
uniprot id: A0A8M1MEP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

29088:THRB
gene id: 29088:THRB
uniprot id: A0A2Y9G680
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

29088:LOC110586872
gene id: 29088:LOC110586872
uniprot id: A0A8M1MRM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-H/MCM16 family.
messages: Nucleus
messages: kinetochore

29088:PLIN5
gene id: 29088:PLIN5
uniprot id: A0A2Y9IAV6
names: Similarity
messages: Belongs to the perilipin family.

29088:FAT2
gene id: 29088:FAT2
uniprot id: A0A2Y9HYC2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SFR1
gene id: 29088:SFR1
uniprot id: A0A2Y9HVK4
uniprot id: A0A8M1MF99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

29088:AKT3
gene id: 29088:AKT3
uniprot id: A0A8M1MET2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

29088:RAP2B
gene id: 29088:RAP2B
uniprot id: A0A8M1MJM1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

29088:ZDHHC5
gene id: 29088:ZDHHC5
uniprot id: A0A2Y9GPB1
uniprot id: A0A2Y9GPM7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

29088:TEKT1
gene id: 29088:TEKT1
uniprot id: A0A2Y9HFR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

29088:DHX29
gene id: 29088:DHX29
uniprot id: A0A2Y9I1R3
uniprot id: A0A8M1MJ89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity.
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Cytoplasm
messages: Part of the 43S pre-initiation complex (PIC) that contains at least Met-tRNA, EIF1, EIF1A (EIF1AX or EIF1AY), EIF2S1, EIF2S2, EIF2S3, EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L, EIF3M, DHX29 and the 40S ribosomal subunit.

29088:LZTS2
gene id: 29088:LZTS2
uniprot id: A0A2Y9HWA9
uniprot id: A0A2Y9I2M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTS2 family.
messages: Cytoplasm
messages: Interacts with KATNB1. Also interacts with CTNNB1, gamma-tubulin and KIF23.
messages: Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
messages: centrosome

29088:TNNT2
gene id: 29088:TNNT2
uniprot id: A0A2Y9GK89
uniprot id: A0A2Y9GLX9
uniprot id: A0A8M1MGY0
uniprot id: A0A8M1MM08
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

29088:PHETA2
gene id: 29088:PHETA2
uniprot id: A0A2Y9H210
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Forms homodimers and heterodimers with PHETA. Interacts with OCRL and INPP5B.
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

29088:VTA1
gene id: 29088:VTA1
uniprot id: A0A2Y9HB25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

29088:FOXO1
gene id: 29088:FOXO1
uniprot id: A0A2Y9G4S0
names: Subcellular Location Annotation
messages: Nucleus

29088:THBD
gene id: 29088:THBD
uniprot id: A0A2Y9I2E6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with ITGAL, ITGAM and ITGB2.
messages: Membrane
messages: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

29088:FBLN1
gene id: 29088:FBLN1
uniprot id: A0A2Y9H0C2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:PDE4DIPP2
gene id: 29088:PDE4DIPP2
uniprot id: A0A2Y9H2G7
uniprot id: A0A2Y9H2I2
uniprot id: A0A2Y9H2K4
uniprot id: A0A2Y9H7H0
uniprot id: A0A8M1M9I9
uniprot id: A0A8M1M9S7
uniprot id: A0A8M1MBW4
uniprot id: A0A8M1MBW9
uniprot id: A0A8M1MBX5
uniprot id: A0A8M1MD99
uniprot id: A0A8M1MI03
names: Subcellular Location Annotation
messages: centrosome

29088:IRAK4
gene id: 29088:IRAK4
uniprot id: A0A2Y9I997
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

29088:CACNA1A
gene id: 29088:CACNA1A
uniprot id: A0A8M1M5D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents.

29088:CUL9
gene id: 29088:CUL9
uniprot id: A0A8M1MJF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cullin family.
messages: Cytoplasm

29088:BRAF
gene id: 29088:BRAF
uniprot id: A0A8M1MQM8
uniprot id: A0A8M1MQN3
uniprot id: A0A8M1MQN6
uniprot id: A0A8M1MSI7
uniprot id: A0A8M1MSJ1
uniprot id: A0A8M1MTW7
uniprot id: A0A8M1MYC9
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

29088:TACSTD2
gene id: 29088:TACSTD2
uniprot id: A0A2Y9GQN2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:EPHA3
gene id: 29088:EPHA3
uniprot id: A0A2Y9H0M4
uniprot id: A0A2Y9H5A8
names: Subcellular Location Annotation
messages: Membrane

29088:CHMP2A
gene id: 29088:CHMP2A
uniprot id: A0A2Y9H7D3
names: Similarity
messages: Belongs to the SNF7 family.

29088:SH2D1A
gene id: 29088:SH2D1A
uniprot id: A0A2Y9GR50
uniprot id: A0A2Y9GUX8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2.

29088:TIGD7
gene id: 29088:TIGD7
uniprot id: A0A2Y9HPW7
names: Subcellular Location Annotation
messages: Nucleus

29088:CORO6
gene id: 29088:CORO6
uniprot id: A0A2Y9I785
uniprot id: A0A2Y9I7I1
uniprot id: A0A2Y9I815
uniprot id: A0A8M1MX92
uniprot id: A0A8M1MZ49
names: Similarity
messages: Belongs to the WD repeat coronin family.

29088:RBM15
gene id: 29088:RBM15
uniprot id: A0A2Y9H2G6
uniprot id: A0A2Y9H2I0
names: Similarity
messages: Belongs to the RRM Spen family.

29088:LOC110574682
gene id: 29088:LOC110574682
uniprot id: A0A2Y9GMJ7
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

29088:LOC110576922
gene id: 29088:LOC110576922
uniprot id: A0A8M1MTI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

29088:EIF3I
gene id: 29088:EIF3I
uniprot id: A0A2Y9GN27
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Phosphorylated by TGF-beta type II receptor.

29088:SPNS3
gene id: 29088:SPNS3
uniprot id: A0A8M1MXL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

29088:FAM110D
gene id: 29088:FAM110D
uniprot id: A0A2Y9GJA5
names: Similarity
messages: Belongs to the FAM110 family.

29088:LOC110578566
gene id: 29088:LOC110578566
uniprot id: A0A2Y9GWQ7
uniprot id: A0A2Y9GX11
uniprot id: A0A2Y9GX36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Golgi pH regulator (TC 1.A.38) family.
messages: Membrane

29088:HTR2A
gene id: 29088:HTR2A
uniprot id: A0A2Y9HPT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin).
messages: Membrane
messages: Presynapse
messages: Synapse
messages: Vesicle
messages: axon
messages: caveola
messages: dendrite

29088:RAPGEF2
gene id: 29088:RAPGEF2
uniprot id: A0A2Y9HWY0
uniprot id: A0A8M1M4J5
uniprot id: A0A8M1M4U5
uniprot id: A0A8M1M8G9
uniprot id: A0A8M1MCK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAPGEF2 family.
messages: Cell junction
messages: Endosome
messages: Late endosome
messages: perinuclear region

29088:VDAC1
gene id: 29088:VDAC1
uniprot id: A0A2Y9I6H3
uniprot id: A0A8M1MGV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft

29088:TTN
gene id: 29088:TTN
uniprot id: A0A8M1MF61
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

29088:CPAMD8
gene id: 29088:CPAMD8
uniprot id: A0A2Y9GNH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

29088:PHOX2A
gene id: 29088:PHOX2A
uniprot id: A0A2Y9I9H8
names: Subcellular Location Annotation
messages: Nucleus

29088:KRT82
gene id: 29088:KRT82
uniprot id: A0A2Y9GT13
names: Similarity
messages: Belongs to the intermediate filament family.

29088:SMS
gene id: 29088:SMS
uniprot id: A0A8M1M543
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

29088:AGA
gene id: 29088:AGA
uniprot id: A0A2Y9HDS5
uniprot id: A0A2Y9HK77
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

29088:RRP8
gene id: 29088:RRP8
uniprot id: A0A2Y9GQ89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: Component of the eNoSC complex.
messages: Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase.
messages: nucleolus

29088:LOC110573415
gene id: 29088:LOC110573415
uniprot id: A0A2Y9GEU4
uniprot id: A0A8M1MGI5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:NR1I2
gene id: 29088:NR1I2
uniprot id: A0A8M1MSB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

29088:UNC50
gene id: 29088:UNC50
uniprot id: A0A2Y9HYZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

29088:MTMR7
gene id: 29088:MTMR7
uniprot id: A0A2Y9HJT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

29088:LOC110593578
gene id: 29088:LOC110593578
uniprot id: A0A2Y9IDS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:NDUFB11
gene id: 29088:NDUFB11
uniprot id: A0A2Y9GB08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB11 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane

29088:HCN2
gene id: 29088:HCN2
uniprot id: A0A8M1M5U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

29088:BCL2L14
gene id: 29088:BCL2L14
uniprot id: A0A2Y9HAL5
names: Similarity
messages: Belongs to the Bcl-2 family.

29088:CHFR
gene id: 29088:CHFR
uniprot id: A0A2Y9H8B5
uniprot id: A0A2Y9H8E5
uniprot id: A0A2Y9H8J0
uniprot id: A0A2Y9H8J5
uniprot id: A0A2Y9HE16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHFR family.
messages: PML body

29088:CCN4
gene id: 29088:CCN4
uniprot id: A0A2Y9GYS6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:ATG16L1
gene id: 29088:ATG16L1
uniprot id: A0A2Y9G6Q4
uniprot id: A0A2Y9G966
uniprot id: A0A8M1M7F7
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

29088:SERPINF2
gene id: 29088:SERPINF2
uniprot id: A0A2Y9IC56
uniprot id: A0A2Y9IEV5
names: Similarity
messages: Belongs to the serpin family.

29088:LOC110573446
gene id: 29088:LOC110573446
uniprot id: A0A2Y9GEX0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SLC26A7
gene id: 29088:SLC26A7
uniprot id: A0A2Y9GXG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

29088:LOC110576807
gene id: 29088:LOC110576807
uniprot id: A0A8M1M4I4
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

29088:LOC123323391
gene id: 29088:LOC123323391
uniprot id: A0A8M1M138
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:GALNTL6
gene id: 29088:GALNTL6
uniprot id: A0A2Y9HYV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:BSPH1
gene id: 29088:BSPH1
uniprot id: A0A2Y9GCM3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:TAF1D
gene id: 29088:TAF1D
uniprot id: A0A2Y9GAI5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. Interacts with UBTF.
messages: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
messages: Nucleus

29088:LOC110582613
gene id: 29088:LOC110582613
uniprot id: A0A2Y9H9I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

29088:ADAMTS5
gene id: 29088:ADAMTS5
uniprot id: A0A2Y9G4D3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:PAQR7
gene id: 29088:PAQR7
uniprot id: A0A2Y9GJH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

29088:LOC110594052
gene id: 29088:LOC110594052
uniprot id: A0A2Y9IB59
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ARSD
gene id: 29088:ARSD
uniprot id: A0A2Y9GML4
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

29088:AKAP13
gene id: 29088:AKAP13
uniprot id: A0A8M1MTS6
names: Subcellular Location Annotation
messages: Cytoplasm

29088:DYNLT4
gene id: 29088:DYNLT4
uniprot id: A0A2Y9GK27
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

29088:GAP43
gene id: 29088:GAP43
uniprot id: A0A2Y9HET9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neuromodulin family.
messages: Cell membrane
messages: Cytoplasm
messages: Identified in a complex containing FGFR4, NCAM1, CDH2, PLCG1, FRS2, SRC, SHC1, GAP43 and CTTN. Interacts (via IQ domain) with calmodulin. Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.
messages: Membrane
messages: Palmitoylated. Palmitoylation is essential for plasma membrane association.
messages: Perikaryon
messages: Synapse
messages: This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
messages: axon
messages: dendrite
messages: filopodium membrane
messages: growth cone membrane

29088:ADAM29
gene id: 29088:ADAM29
uniprot id: A0A2Y9HRP5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:HMX3
gene id: 29088:HMX3
uniprot id: A0A2Y9I6B7
names: Subcellular Location Annotation
messages: Nucleus

29088:RDH10
gene id: 29088:RDH10
uniprot id: A0A2Y9GXB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

29088:FDXR
gene id: 29088:FDXR
uniprot id: A0A2Y9GC37
uniprot id: A0A8M1MTX4
uniprot id: A0A8M1MTX8
uniprot id: A0A8M1MVQ4
uniprot id: A0A8M1MWW3
uniprot id: A0A8M1MZ07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion
messages: Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.

29088:MPP1
gene id: 29088:MPP1
uniprot id: A0A2Y9GH92
uniprot id: A0A2Y9GM61
uniprot id: A0A8M1M4Z8
names: Function
names: Subcellular Location Annotation
messages: Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity.
messages: stereocilium

29088:FHIP1B
gene id: 29088:FHIP1B
uniprot id: A0A2Y9GQB3
uniprot id: A0A8M1MPG8
uniprot id: A0A8M1MXY2
names: Similarity
messages: Belongs to the FHIP family.

29088:LOC110592009
gene id: 29088:LOC110592009
uniprot id: A0A2Y9I3Z3
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

29088:KRT72
gene id: 29088:KRT72
uniprot id: A0A2Y9GSZ4
uniprot id: A0A2Y9GT87
names: Similarity
messages: Belongs to the intermediate filament family.

29088:COMTD1
gene id: 29088:COMTD1
uniprot id: A0A8M1MH54
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

29088:LOC110583467
gene id: 29088:LOC110583467
uniprot id: A0A8M1MJZ4
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

29088:TOB1
gene id: 29088:TOB1
uniprot id: A0A2Y9I7J7
names: Similarity
messages: Belongs to the BTG family.

29088:SDR42E2
gene id: 29088:SDR42E2
uniprot id: A0A2Y9GTA9
names: Similarity
messages: Belongs to the 3-beta-HSD family.

29088:ATP6V0A4
gene id: 29088:ATP6V0A4
uniprot id: A0A2Y9HA77
uniprot id: A0A8M1MQQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

29088:LOC110576551
gene id: 29088:LOC110576551
uniprot id: A0A2Y9GVX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110591666
gene id: 29088:LOC110591666
uniprot id: A0A8M1MQH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.
messages: Nucleus
messages: nucleolus

29088:HS3ST1
gene id: 29088:HS3ST1
uniprot id: A0A2Y9G660
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

29088:FAM151A
gene id: 29088:FAM151A
uniprot id: A0A2Y9GNY7
names: Similarity
messages: Belongs to the FAM151 family.

29088:PARD6B
gene id: 29088:PARD6B
uniprot id: A0A2Y9GQU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

29088:CCHCR1
gene id: 29088:CCHCR1
uniprot id: A0A2Y9HLG8
uniprot id: A0A8M1MIG7
uniprot id: A0A8M1MIH2
uniprot id: A0A8M1MKI9
uniprot id: A0A8M1MLV1
uniprot id: A0A8M1MSG8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a regulator of keratinocyte proliferation or differentiation.
messages: Nucleus

29088:LOC110578880
gene id: 29088:LOC110578880
uniprot id: A0A8M1MC85
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

29088:SNX13
gene id: 29088:SNX13
uniprot id: A0A2Y9H7B6
names: Similarity
messages: Belongs to the sorting nexin family.

29088:P2RY13
gene id: 29088:P2RY13
uniprot id: A0A2Y9GQR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:BRF2
gene id: 29088:BRF2
uniprot id: A0A2Y9GDZ5
names: Similarity
messages: Belongs to the TFIIB family.

29088:FAM83G
gene id: 29088:FAM83G
uniprot id: A0A2Y9HEF3
uniprot id: A0A2Y9HEU7
names: Similarity
messages: Belongs to the FAM83 family.

29088:CAV1
gene id: 29088:CAV1
uniprot id: A0A2Y9HTF7
uniprot id: A0A2Y9HTZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner (By similarity). Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway (By similarity). Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation.
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: Membrane raft
messages: caveola

29088:RIMKLB
gene id: 29088:RIMKLB
uniprot id: A0A2Y9H384
names: Similarity
messages: Belongs to the RimK family.

29088:NDUFA1
gene id: 29088:NDUFA1
uniprot id: A0A2Y9GRM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:DIAPH3
gene id: 29088:DIAPH3
uniprot id: A0A2Y9HP53
uniprot id: A0A2Y9HPA4
uniprot id: A0A2Y9HVX3
names: Similarity
messages: Belongs to the formin homology family. Diaphanous subfamily.

29088:DIMT1
gene id: 29088:DIMT1
uniprot id: A0A2Y9I192
uniprot id: A0A2Y9I1N9
uniprot id: A0A2Y9I859
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

29088:ART3
gene id: 29088:ART3
uniprot id: A0A2Y9I2P5
uniprot id: A0A2Y9I953
uniprot id: A0A8M1M4E1
uniprot id: A0A8M1M6J3
uniprot id: A0A8M1M814
uniprot id: A0A8M1MC29
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

29088:TCP11X2
gene id: 29088:TCP11X2
uniprot id: A0A2Y9GPC7
names: Similarity
messages: Belongs to the TCP11 family.

29088:RIBC1
gene id: 29088:RIBC1
uniprot id: A0A2Y9HRR4
uniprot id: A0A2Y9HSF4
names: Similarity
messages: Belongs to the RIB43A family.

29088:SPCS3
gene id: 29088:SPCS3
uniprot id: A0A2Y9HK73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane

29088:CR2
gene id: 29088:CR2
uniprot id: A0A2Y9GGG4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110577176
gene id: 29088:LOC110577176
uniprot id: A0A2Y9GW69
names: Subcellular Location Annotation
messages: Nucleus

29088:DNASE1
gene id: 29088:DNASE1
uniprot id: A0A2Y9HWF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNase I family.
messages: Nucleus envelope
messages: Zymogen granule

29088:VEPH1
gene id: 29088:VEPH1
uniprot id: A0A2Y9I7N8
uniprot id: A0A2Y9I9T6
names: Similarity
messages: Belongs to the MELT/VEPH family.

29088:SLC34A2
gene id: 29088:SLC34A2
uniprot id: A0A2Y9GAI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Involved in actively transporting phosphate into cells via Na(+) cotransport.
messages: Membrane

29088:GTF2IRD1
gene id: 29088:GTF2IRD1
uniprot id: A0A8M1MB23
uniprot id: A0A8M1MBA0
names: Subcellular Location Annotation
messages: Nucleus

29088:RPL10
gene id: 29088:RPL10
uniprot id: A0A8M1M1S6
uniprot id: A0A8M1M227
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

29088:TERT
gene id: 29088:TERT
uniprot id: A0A2Y9GU74
uniprot id: A0A2Y9GU79
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.
messages: The RNA-interacting domain 1 (RD1)/N-terminal extension (NTE) is required for interaction with the pseudoknot-template domain of each of TERC dimers. It contains anchor sites that bind primer nucleotides upstream of the RNA-DNA hybrid and is thus an essential determinant of repeat addition processivity.
messages: The RNA-interacting domain 2 (RD2) is essential for both interaction with the CR4-CR5 domain of TERC and for DNA synthesis.
messages: The primer grip sequence in the RT domain is required for telomerase activity and for stable association with short telomeric primers.
messages: nucleolus
messages: nucleoplasm
messages: telomere

29088:LOC110593550
gene id: 29088:LOC110593550
uniprot id: A0A2Y9IDQ9
names: Similarity
messages: Belongs to the intermediate filament family.

29088:NEMP2
gene id: 29088:NEMP2
uniprot id: A0A2Y9I4G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

29088:ZDHHC24
gene id: 29088:ZDHHC24
uniprot id: A0A2Y9GSG0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

29088:LOC110587356
gene id: 29088:LOC110587356
uniprot id: A0A8M1MPY5
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

29088:KDM4C
gene id: 29088:KDM4C
uniprot id: A0A8M1MU11
names: Similarity
messages: Belongs to the JHDM3 histone demethylase family.

29088:QSOX1
gene id: 29088:QSOX1
uniprot id: A0A2Y9GKC8
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

29088:LOC110588681
gene id: 29088:LOC110588681
uniprot id: A0A8M1MM22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

29088:LRP10
gene id: 29088:LRP10
uniprot id: A0A2Y9HGZ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110586908
gene id: 29088:LOC110586908
uniprot id: A0A8M1MLJ5
uniprot id: A0A8M1MS49
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse
messages: axon
messages: dendrite

29088:DNAJC18
gene id: 29088:DNAJC18
uniprot id: A0A2Y9I199
names: Subcellular Location Annotation
messages: Membrane

29088:STMN4
gene id: 29088:STMN4
uniprot id: A0A2Y9HZD9
uniprot id: A0A8M1M4T5
uniprot id: A0A8M1M8G0
names: Similarity
messages: Belongs to the stathmin family.

29088:PLP1
gene id: 29088:PLP1
uniprot id: A0A2Y9H5X8
uniprot id: A0A2Y9HCL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

29088:HYLS1
gene id: 29088:HYLS1
uniprot id: A0A2Y9HQN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HYLS1 family.
messages: centriole
messages: cilium

29088:FAM13B
gene id: 29088:FAM13B
uniprot id: A0A8M1MFG1
names: Similarity
messages: Belongs to the FAM13 family.

29088:SPAG9
gene id: 29088:SPAG9
uniprot id: A0A2Y9ICC9
uniprot id: A0A2Y9IF35
uniprot id: A0A8M1MXF6
names: Similarity
messages: Belongs to the JIP scaffold family.

29088:LOC110584316
gene id: 29088:LOC110584316
uniprot id: A0A8M1MRF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:FRK
gene id: 29088:FRK
uniprot id: A0A2Y9HBG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

29088:LOC110587247
gene id: 29088:LOC110587247
uniprot id: A0A2Y9HUY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm
messages: nucleoplasm

29088:AHCYL1
gene id: 29088:AHCYL1
uniprot id: A0A2Y9H7U7
uniprot id: A0A2Y9H9G7
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

29088:FIBIN
gene id: 29088:FIBIN
uniprot id: A0A2Y9GQS7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FIBIN family.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer; disulfide-linked. Seems to also exist as monomers.
messages: Secreted

29088:DSTN
gene id: 29088:DSTN
uniprot id: A0A2Y9I4D5
names: Function
names: Similarity
messages: Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner.
messages: Belongs to the actin-binding proteins ADF family.

29088:ALAS1
gene id: 29088:ALAS1
uniprot id: A0A8M1MGA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

29088:CPT2
gene id: 29088:CPT2
uniprot id: A0A2Y9GL98
uniprot id: A0A2Y9GRR5
uniprot id: A0A8M1M9J1
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

29088:DHRS7C
gene id: 29088:DHRS7C
uniprot id: A0A2Y9HF63
uniprot id: A0A2Y9HLG3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:LOC110590269
gene id: 29088:LOC110590269
uniprot id: A0A8M1MZF3
names: Similarity
messages: Belongs to the SDHAF4 family.

29088:EVA1B
gene id: 29088:EVA1B
uniprot id: A0A2Y9GJM2
names: Similarity
messages: Belongs to the EVA1 family.

29088:TUBAL3
gene id: 29088:TUBAL3
uniprot id: A0A8M1MCB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

29088:LOC110572499
gene id: 29088:LOC110572499
uniprot id: A0A2Y9GBZ0
names: Similarity
messages: Belongs to the threonine aldolase family.

29088:IRX3
gene id: 29088:IRX3
uniprot id: A0A2Y9I8X6
uniprot id: A0A2Y9IDA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

29088:RRM2
gene id: 29088:RRM2
uniprot id: A0A2Y9HTE0
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

29088:SLC30A10
gene id: 29088:SLC30A10
uniprot id: A0A2Y9HQV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

29088:CDC42SE1
gene id: 29088:CDC42SE1
uniprot id: A0A2Y9H188
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Interacts with CDC42 (in GTP-bound form). Interacts weakly with RAC1 and not at all with RHOA.
messages: Membrane
messages: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
messages: cytoskeleton

29088:EXT2
gene id: 29088:EXT2
uniprot id: A0A2Y9GP56
uniprot id: A0A2Y9GPG9
uniprot id: A0A2Y9GUY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:DDX43
gene id: 29088:DDX43
uniprot id: A0A2Y9HI64
names: Similarity
messages: Belongs to the DEAD box helicase family.

29088:NGFR
gene id: 29088:NGFR
uniprot id: A0A2Y9I8J3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC123324335
gene id: 29088:LOC123324335
uniprot id: A0A8M1M717
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

29088:RIOK3
gene id: 29088:RIOK3
uniprot id: A0A2Y9GR09
uniprot id: A0A2Y9GWS0
uniprot id: A0A8M1MTM3
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
messages: Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses.

29088:LOC110582808
gene id: 29088:LOC110582808
uniprot id: A0A2Y9H9T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110585537
gene id: 29088:LOC110585537
uniprot id: A0A2Y9HPK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:BEST3
gene id: 29088:BEST3
uniprot id: A0A2Y9G5G5
uniprot id: A0A2Y9G5W7
uniprot id: A0A2Y9G7Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Membrane

29088:CRISP2
gene id: 29088:CRISP2
uniprot id: A0A2Y9HEI5
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:GOSR1
gene id: 29088:GOSR1
uniprot id: A0A2Y9I709
uniprot id: A0A2Y9IBF8
uniprot id: A0A2Y9IE36
uniprot id: A0A8M1MWY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

29088:CCL24
gene id: 29088:CCL24
uniprot id: A0A2Y9HXJ6
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

29088:LAMA2
gene id: 29088:LAMA2
uniprot id: A0A8M1MRZ9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

29088:PIGG
gene id: 29088:PIGG
uniprot id: A0A2Y9G3G8
uniprot id: A0A2Y9G5I0
uniprot id: A0A8M1M5G2
uniprot id: A0A8M1M7K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:GGA3
gene id: 29088:GGA3
uniprot id: A0A2Y9GCA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

29088:PLAGL2
gene id: 29088:PLAGL2
uniprot id: A0A2Y9H402
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

29088:LOC110582980
gene id: 29088:LOC110582980
uniprot id: A0A2Y9HH45
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: Component of the 40S ribosomal subunit.

29088:LOC110580611
gene id: 29088:LOC110580611
uniprot id: A0A8M1M916
names: Similarity
messages: Belongs to the PDCD5 family.

29088:CCKAR
gene id: 29088:CCKAR
uniprot id: A0A2Y9G7R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

29088:LY6G5C
gene id: 29088:LY6G5C
uniprot id: A0A2Y9HMD7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Forms oligomers.
messages: May have a role in hematopoietic cell differentiation.
messages: Secreted

29088:LOC110585532
gene id: 29088:LOC110585532
uniprot id: A0A2Y9HPJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SERPINC1
gene id: 29088:SERPINC1
uniprot id: A0A2Y9GM84
uniprot id: A0A8M1MDF6
uniprot id: A0A8M1MDK2
uniprot id: A0A8M1MFL7
uniprot id: A0A8M1MM41
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the serpin family.
messages: Forms protease inhibiting heterodimer with TMPRSS7.
messages: extracellular space

29088:LOC110578297
gene id: 29088:LOC110578297
uniprot id: A0A8M1MGI2
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

29088:GPC4
gene id: 29088:GPC4
uniprot id: A0A2Y9GQ42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

29088:PCNX3
gene id: 29088:PCNX3
uniprot id: A0A2Y9GPT8
uniprot id: A0A2Y9GPY3
uniprot id: A0A2Y9GTN8
uniprot id: A0A2Y9GVE1
uniprot id: A0A8M1MX49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

29088:LOC110575858
gene id: 29088:LOC110575858
uniprot id: A0A2Y9GRV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:AP3B2
gene id: 29088:AP3B2
uniprot id: A0A2Y9GB50
uniprot id: A0A2Y9GBA8
uniprot id: A0A2Y9GDW9
uniprot id: A0A2Y9GFF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

29088:LOC110583383
gene id: 29088:LOC110583383
uniprot id: A0A8M1ML70
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

29088:CPSF4
gene id: 29088:CPSF4
uniprot id: A0A2Y9GA55
uniprot id: A0A2Y9GA82
uniprot id: A0A2Y9GE10
uniprot id: A0A8M1MLD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

29088:MRPL50
gene id: 29088:MRPL50
uniprot id: A0A2Y9H660
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

29088:ING4
gene id: 29088:ING4
uniprot id: A0A2Y9H466
uniprot id: A0A2Y9H496
uniprot id: A0A2Y9H9J5
uniprot id: A0A8M1MC37
uniprot id: A0A8M1MC84
uniprot id: A0A8M1MFQ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

29088:ADD2
gene id: 29088:ADD2
uniprot id: A0A2Y9HSQ3
uniprot id: A0A2Y9HT66
uniprot id: A0A2Y9HT84
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

29088:LOC110582374
gene id: 29088:LOC110582374
uniprot id: A0A2Y9HFF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:FBXO9
gene id: 29088:FBXO9
uniprot id: A0A2Y9HE59
names: Subcellular Location Annotation
messages: Cytoplasm

29088:SNF8
gene id: 29088:SNF8
uniprot id: A0A2Y9I6R2
uniprot id: A0A8M1MZ30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

29088:KATNA1
gene id: 29088:KATNA1
uniprot id: A0A2Y9HAX0
names: Activity Regulation
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit. Interacts with ASPM; the katanin complex formation KATNA1:KATNB1 is required for the association of ASPM. Interacts with dynein and NDEL1. Associates with the E3 ligase complex containing DYRK2, EDD/UBR5, DDB1 and DCAF1 proteins (EDVP complex). Interacts with KLHL42 (via the kelch domains). Interacts with CUL3; the interaction is enhanced by KLHL42. Interacts with KATNB1 and KATNBL1. Interacts with CAMSAP2 and CAMSAP3; leading to regulate the length of CAMSAP-decorated microtubule stretches.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
messages: Cytoplasm
messages: Midbody
messages: Phosphorylation by DYRK2 triggers ubiquitination and subsequent degradation.
messages: The N-terminus is sufficient for interaction with microtubules, although high affinity binding to microtubules also requires an intact C-terminal domain and ATP, which promotes oligomerization.
messages: Ubiquitinated by the BCR(KLHL42) E3 ubiquitin ligase complex, leading to its proteasomal degradation. Ubiquitinated by the EDVP E3 ligase complex and subsequently targeted for proteasomal degradation.
messages: centrosome
messages: spindle
messages: spindle pole

29088:NDUFS7
gene id: 29088:NDUFS7
uniprot id: A0A2Y9IAE6
uniprot id: A0A2Y9IB07
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

29088:ADAMTS8
gene id: 29088:ADAMTS8
uniprot id: A0A2Y9HK81
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:SOST
gene id: 29088:SOST
uniprot id: A0A2Y9GIL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the sclerostin family.
messages: Interacts with LRP4 (via the extracellular domain); the interaction facilitates the inhibition of Wnt signaling. Interacts with LRP5 (via the first two YWTD-EGF repeat domains); the interaction inhibits Wnt-mediated signaling. Interacts with LRP6.
messages: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

29088:LOC110589452
gene id: 29088:LOC110589452
uniprot id: A0A8M1MIT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus

29088:DDX3X
gene id: 29088:DDX3X
uniprot id: A0A2Y9GEZ2
uniprot id: A0A2Y9GF64
uniprot id: A0A8M1M1P0
uniprot id: A0A8M1M1Z6
uniprot id: A0A8M1M5R2
uniprot id: A0A8M1M9J2
names: Similarity
messages: Belongs to the DEAD box helicase family.

29088:EFNA5
gene id: 29088:EFNA5
uniprot id: A0A2Y9HZN4
uniprot id: A0A2Y9I059
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:FOXP3
gene id: 29088:FOXP3
uniprot id: A0A2Y9G9J3
uniprot id: A0A2Y9G9J6
names: Subcellular Location Annotation
messages: Nucleus

29088:RIPPLY2
gene id: 29088:RIPPLY2
uniprot id: A0A2Y9HI32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

29088:CDK6
gene id: 29088:CDK6
uniprot id: A0A2Y9H122
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:ZNF711
gene id: 29088:ZNF711
uniprot id: A0A2Y9GIL4
uniprot id: A0A8M1M3E4
names: Subcellular Location Annotation
messages: Nucleus

29088:SGSM3
gene id: 29088:SGSM3
uniprot id: A0A2Y9GVN4
uniprot id: A0A2Y9H012
uniprot id: A0A8M1MD36
uniprot id: A0A8M1MGK6
uniprot id: A0A8M1MLL6
names: Similarity
messages: Belongs to the small G protein signaling modulator family.

29088:LOC110582150
gene id: 29088:LOC110582150
uniprot id: A0A8M1MA40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

29088:PAN3
gene id: 29088:PAN3
uniprot id: A0A2Y9G4Q1
uniprot id: A0A2Y9G4S1
uniprot id: A0A2Y9G8B8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PABPC1 (via PABC domain), conferring substrate specificity of the enzyme complex. Interacts with the GW182 family proteins TNRC6A, TNRC6B and TNRC6C.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: P-body
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

29088:ARAF
gene id: 29088:ARAF
uniprot id: A0A8M1M1I9
uniprot id: A0A8M1M1U7
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

29088:PROKR1
gene id: 29088:PROKR1
uniprot id: A0A2Y9HYF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

29088:CA12
gene id: 29088:CA12
uniprot id: A0A2Y9HD30
uniprot id: A0A2Y9HDB3
uniprot id: A0A2Y9HJ57
uniprot id: A0A2Y9HJL2
uniprot id: A0A8M1MJS3
uniprot id: A0A8M1MN47
uniprot id: A0A8M1MTU1
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

29088:LOC110590978
gene id: 29088:LOC110590978
uniprot id: A0A8M1MQJ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

29088:ADGRF1
gene id: 29088:ADGRF1
uniprot id: A0A2Y9H7S7
names: Subcellular Location Annotation
messages: Membrane

29088:MAL2
gene id: 29088:MAL2
uniprot id: A0A2Y9GYL0
uniprot id: A0A2Y9H383
names: Subcellular Location Annotation
messages: Membrane

29088:FOXC2
gene id: 29088:FOXC2
uniprot id: A0A2Y9I2H8
names: Subcellular Location Annotation
messages: Nucleus

29088:TCEA1
gene id: 29088:TCEA1
uniprot id: A0A2Y9GX98
uniprot id: A0A2Y9H3H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

29088:SDF4
gene id: 29088:SDF4
uniprot id: A0A8M1MFN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Golgi apparatus lumen

29088:LOC110582475
gene id: 29088:LOC110582475
uniprot id: A0A2Y9H976
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

29088:SV2B
gene id: 29088:SV2B
uniprot id: A0A2Y9GAZ5
uniprot id: A0A2Y9GB36
uniprot id: A0A2Y9GB51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

29088:GNRHR
gene id: 29088:GNRHR
uniprot id: A0A2Y9I2K1
uniprot id: A0A2Y9I763
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system.

29088:ARMC9
gene id: 29088:ARMC9
uniprot id: A0A2Y9H325
uniprot id: A0A8M1M8P0
uniprot id: A0A8M1MA29
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with TOGARAM1, CCDC66, CEP104, CSPP1 and CEP290.
messages: centriole
messages: cilium
messages: cilium basal body

29088:CTNNAL1
gene id: 29088:CTNNAL1
uniprot id: A0A8M1MQX8
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

29088:OPTN
gene id: 29088:OPTN
uniprot id: A0A2Y9HKY4
uniprot id: A0A2Y9HRL9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Endosome
messages: Golgi apparatus
messages: May act by regulating membrane trafficking and cellular morphogenesis.
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: perinuclear region
messages: trans-Golgi network

29088:LOC110583361
gene id: 29088:LOC110583361
uniprot id: A0A2Y9HBN0
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

29088:HSF4
gene id: 29088:HSF4
uniprot id: A0A8M1MXL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

29088:UBE2I
gene id: 29088:UBE2I
uniprot id: A0A2Y9HV78
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:HCRT
gene id: 29088:HCRT
uniprot id: A0A2Y9GH97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the orexin family.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum
messages: Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested.
messages: Rough endoplasmic reticulum
messages: Synapse
messages: Vesicle

29088:PPIB
gene id: 29088:PPIB
uniprot id: A0A2Y9HJV7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

29088:LOC110593150
gene id: 29088:LOC110593150
uniprot id: A0A2Y9I8M2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SLC16A7
gene id: 29088:SLC16A7
uniprot id: A0A2Y9GUH9
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cytoplasm
messages: Membrane

29088:LOC110572820
gene id: 29088:LOC110572820
uniprot id: A0A2Y9GD03
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

29088:FAM214B
gene id: 29088:FAM214B
uniprot id: A0A2Y9H657
names: Similarity
messages: Belongs to the FAM214 family.

29088:RABGGTA
gene id: 29088:RABGGTA
uniprot id: A0A2Y9HHK9
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.

29088:TGM3
gene id: 29088:TGM3
uniprot id: A0A2Y9GZV6
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

29088:MRPL53
gene id: 29088:MRPL53
uniprot id: A0A2Y9HSV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

29088:LOC110590429
gene id: 29088:LOC110590429
uniprot id: A0A2Y9HZA1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

29088:CCDC149
gene id: 29088:CCDC149
uniprot id: A0A2Y9G7X7
names: Similarity
messages: Belongs to the CCDC149 family.

29088:ST6GAL1
gene id: 29088:ST6GAL1
uniprot id: A0A2Y9H8T8
uniprot id: A0A2Y9HFJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

29088:LOC110580985
gene id: 29088:LOC110580985
uniprot id: A0A8M1MCT2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

29088:PIF1
gene id: 29088:PIF1
uniprot id: A0A2Y9HDF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity.
messages: Mitochondrion
messages: Monomer. Interacts with telomerase.
messages: Nucleus

29088:LOC110571755
gene id: 29088:LOC110571755
uniprot id: A0A8M1MLH7
names: Similarity
messages: Belongs to the serpin family.

29088:LOC110589717
gene id: 29088:LOC110589717
uniprot id: A0A8M1MF63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

29088:BRI3
gene id: 29088:BRI3
uniprot id: A0A2Y9GCV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRI3 family.
messages: Membrane
messages: perinuclear region

29088:SLC2A1
gene id: 29088:SLC2A1
uniprot id: A0A2Y9GL66
uniprot id: A0A2Y9GLD5
uniprot id: A0A8M1MCZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Membrane
messages: Photoreceptor inner segment

29088:LOC110583215
gene id: 29088:LOC110583215
uniprot id: A0A8M1MKW9
uniprot id: A0A8M1MRF5
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

29088:FGF11
gene id: 29088:FGF11
uniprot id: A0A2Y9HEZ9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

29088:CPD
gene id: 29088:CPD
uniprot id: A0A2Y9I8M4
names: Similarity
messages: Belongs to the peptidase M14 family.

29088:LOC110587482
gene id: 29088:LOC110587482
uniprot id: A0A2Y9HP70
names: Similarity
messages: Belongs to the TTC39 family.

29088:SUCLG2
gene id: 29088:SUCLG2
uniprot id: A0A2Y9HGZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.
messages: Mitochondrion

29088:EIF4EBP2
gene id: 29088:EIF4EBP2
uniprot id: A0A2Y9I149
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

29088:PARP6
gene id: 29088:PARP6
uniprot id: A0A2Y9HDA7
uniprot id: A0A2Y9HDE1
uniprot id: A0A2Y9HDN8
uniprot id: A0A8M1MKH1
names: Similarity
messages: Belongs to the ARTD/PARP family.

29088:ADAM19
gene id: 29088:ADAM19
uniprot id: A0A2Y9HNP3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:PIWIL3
gene id: 29088:PIWIL3
uniprot id: A0A2Y9I632
names: Similarity
messages: Belongs to the argonaute family.

29088:GABRG3
gene id: 29088:GABRG3
uniprot id: A0A8M1MSM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:FFAR1
gene id: 29088:FFAR1
uniprot id: A0A2Y9I2X1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:LOC110586345
gene id: 29088:LOC110586345
uniprot id: A0A8M1MXQ3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MTMR12
gene id: 29088:MTMR12
uniprot id: A0A8M1MII5
uniprot id: A0A8M1MJU9
uniprot id: A0A8M1MQ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Sarcoplasmic reticulum
messages: sarcomere

29088:ATP5PB
gene id: 29088:ATP5PB
uniprot id: A0A2Y9H7T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

29088:FOXL2
gene id: 29088:FOXL2
uniprot id: A0A2Y9G6B0
names: Subcellular Location Annotation
messages: Nucleus

29088:NODAL
gene id: 29088:NODAL
uniprot id: A0A2Y9HVR5
names: Similarity
messages: Belongs to the TGF-beta family.

29088:SGMS2
gene id: 29088:SGMS2
uniprot id: A0A2Y9GLY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

29088:KCNJ6
gene id: 29088:KCNJ6
uniprot id: A0A2Y9G459
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ6 subfamily.
messages: Membrane

29088:TIGD5
gene id: 29088:TIGD5
uniprot id: A0A2Y9GYI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

29088:AK2
gene id: 29088:AK2
uniprot id: A0A2Y9GKX6
uniprot id: A0A2Y9GRC6
uniprot id: A0A8M1M963
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.

29088:CCNL1
gene id: 29088:CCNL1
uniprot id: A0A2Y9I7L4
uniprot id: A0A2Y9I9Q5
uniprot id: A0A8M1MQK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin L subfamily.
messages: Nucleus speckle
messages: nucleoplasm

29088:C16H19orf12
gene id: 29088:C16H19orf12
uniprot id: A0A2Y9HYE1
uniprot id: A0A2Y9HYI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

29088:OVCA2
gene id: 29088:OVCA2
uniprot id: A0A2Y9I6N2
names: Similarity
messages: Belongs to the LovG family.

29088:PIGW
gene id: 29088:PIGW
uniprot id: A0A2Y9IC86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

29088:WNT4
gene id: 29088:WNT4
uniprot id: A0A2Y9GQE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

29088:AP2B1
gene id: 29088:AP2B1
uniprot id: A0A2Y9I8G3
uniprot id: A0A2Y9IFM8
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

29088:GCGR
gene id: 29088:GCGR
uniprot id: A0A8M1MU15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

29088:ATP1B3
gene id: 29088:ATP1B3
uniprot id: A0A2Y9G877
names: Similarity
messages: Belongs to the X(+)/potassium ATPases subunit beta family.

29088:LOC110572802
gene id: 29088:LOC110572802
uniprot id: A0A8M1M4Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane

29088:CCT7
gene id: 29088:CCT7
uniprot id: A0A2Y9HZZ4
uniprot id: A0A8M1MNT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

29088:NEU2
gene id: 29088:NEU2
uniprot id: A0A2Y9HCX5
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

29088:TMEM70
gene id: 29088:TMEM70
uniprot id: A0A2Y9H4W7
names: Similarity
messages: Belongs to the TMEM70 family.

29088:MSTO1
gene id: 29088:MSTO1
uniprot id: A0A2Y9GF70
uniprot id: A0A2Y9GFD0
uniprot id: A0A2Y9GFE2
uniprot id: A0A2Y9GK19
uniprot id: A0A8M1MDB3
uniprot id: A0A8M1MGS8
uniprot id: A0A8M1MLU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the misato family.
messages: Mitochondrion outer membrane

29088:GDAP1
gene id: 29088:GDAP1
uniprot id: A0A2Y9GY27
uniprot id: A0A8M1M8H1
names: Similarity
messages: Belongs to the GST superfamily.

29088:SPIRE2
gene id: 29088:SPIRE2
uniprot id: A0A2Y9IFV4
uniprot id: A0A2Y9IIY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

29088:LOC110588857
gene id: 29088:LOC110588857
uniprot id: A0A8M1MPQ5
names: Similarity
messages: Belongs to the GroES chaperonin family.

29088:DRD2
gene id: 29088:DRD2
uniprot id: A0A2Y9HK02
uniprot id: A0A2Y9HK93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

29088:SLC41A2
gene id: 29088:SLC41A2
uniprot id: A0A2Y9GVD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

29088:LOC110585649
gene id: 29088:LOC110585649
uniprot id: A0A2Y9HPU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-H/MCM16 family.
messages: Nucleus
messages: kinetochore

29088:KIF23
gene id: 29088:KIF23
uniprot id: A0A8M1MM72
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110574730
gene id: 29088:LOC110574730
uniprot id: A0A2Y9GJ64
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

29088:KCNAB1
gene id: 29088:KCNAB1
uniprot id: A0A2Y9I2Q2
uniprot id: A0A2Y9I2Z6
uniprot id: A0A2Y9I399
uniprot id: A0A2Y9I7L9
uniprot id: A0A2Y9I9R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

29088:SLC26A6
gene id: 29088:SLC26A6
uniprot id: A0A2Y9GTP2
uniprot id: A0A2Y9GTQ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:NRP1
gene id: 29088:NRP1
uniprot id: A0A2Y9GV14
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:TSHZ1
gene id: 29088:TSHZ1
uniprot id: A0A2Y9GVP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

29088:LOC110593304
gene id: 29088:LOC110593304
uniprot id: A0A8M1M5G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

29088:DYRK1B
gene id: 29088:DYRK1B
uniprot id: A0A2Y9HXP8
uniprot id: A0A2Y9HY11
uniprot id: A0A2Y9I4G0
uniprot id: A0A8M1MVN6
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

29088:LOC110592270
gene id: 29088:LOC110592270
uniprot id: A0A8M1M8D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

29088:TFE3
gene id: 29088:TFE3
uniprot id: A0A8M1M4K3
uniprot id: A0A8M1M9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

29088:LOC110577769
gene id: 29088:LOC110577769
uniprot id: A0A2Y9H082
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

29088:LOC110592839
gene id: 29088:LOC110592839
uniprot id: A0A2Y9I6S1
uniprot id: A0A2Y9IBI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

29088:LOXL2
gene id: 29088:LOXL2
uniprot id: A0A2Y9HS67
uniprot id: A0A8M1M7N6
uniprot id: A0A8M1MBN7
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

29088:LIN9
gene id: 29088:LIN9
uniprot id: A0A2Y9G7X8
uniprot id: A0A8M1MEU2
uniprot id: A0A8M1MEX7
names: Similarity
messages: Belongs to the lin-9 family.

29088:LOC110577476
gene id: 29088:LOC110577476
uniprot id: A0A2Y9GTD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110570458
gene id: 29088:LOC110570458
uniprot id: A0A2Y9G8T3
names: Subcellular Location Annotation
messages: Membrane
messages: chromaffin granule membrane

29088:RPL13
gene id: 29088:RPL13
uniprot id: A0A2Y9I210
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

29088:TFRC
gene id: 29088:TFRC
uniprot id: A0A2Y9H9N3
uniprot id: A0A2Y9H9P8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway.
messages: Homodimer; disulfide-linked.
messages: Melanosome
messages: Membrane
messages: Stearoylated.

29088:GPR119
gene id: 29088:GPR119
uniprot id: A0A2Y9GQ73
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:RNASE1
gene id: 29088:RNASE1
uniprot id: A0A2Y9HP84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

29088:LOC110584247
gene id: 29088:LOC110584247
uniprot id: A0A8M1M9W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

29088:SMU1
gene id: 29088:SMU1
uniprot id: A0A2Y9H727
uniprot id: A0A2Y9HCP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

29088:STING1
gene id: 29088:STING1
uniprot id: A0A2Y9I114
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STING family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: autophagosome membrane
messages: perinuclear region

29088:RHBDF2
gene id: 29088:RHBDF2
uniprot id: A0A2Y9GC84
uniprot id: A0A2Y9GF57
uniprot id: A0A2Y9GGP2
uniprot id: A0A8M1MZC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

29088:PDGFC
gene id: 29088:PDGFC
uniprot id: A0A2Y9HS39
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:LOC110587617
gene id: 29088:LOC110587617
uniprot id: A0A8M1M6U0
names: Similarity
messages: Belongs to the PPP phosphatase family.

29088:LOC110575798
gene id: 29088:LOC110575798
uniprot id: A0A2Y9GMR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110590965
gene id: 29088:LOC110590965
uniprot id: A0A2Y9I5K8
uniprot id: A0A2Y9I7K3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

29088:FBLN2
gene id: 29088:FBLN2
uniprot id: A0A2Y9HG46
names: Caution
names: Similarity
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:EEF1B2
gene id: 29088:EEF1B2
uniprot id: A0A2Y9ICA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
messages: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

29088:MFAP5
gene id: 29088:MFAP5
uniprot id: A0A2Y9H369
uniprot id: A0A2Y9H396
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

29088:IMPG2
gene id: 29088:IMPG2
uniprot id: A0A8M1MMS2
names: Subcellular Location Annotation
messages: interphotoreceptor matrix

29088:LOC110576384
gene id: 29088:LOC110576384
uniprot id: A0A8M1MQF9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

29088:C3H2orf88
gene id: 29088:C3H2orf88
uniprot id: A0A2Y9I5A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small membrane AKAP family.
messages: Cell membrane
messages: Membrane

29088:FAM83D
gene id: 29088:FAM83D
uniprot id: A0A2Y9GZG0
names: Similarity
messages: Belongs to the FAM83 family.

29088:LOC110572705
gene id: 29088:LOC110572705
uniprot id: A0A2Y9GFG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

29088:LOC110577561
gene id: 29088:LOC110577561
uniprot id: A0A2Y9GTN6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:DRAM2
gene id: 29088:DRAM2
uniprot id: A0A2Y9H2J8
uniprot id: A0A2Y9H7K8
names: Subcellular Location Annotation
messages: Membrane

29088:ITGA1
gene id: 29088:ITGA1
uniprot id: A0A2Y9HN92
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:ORMDL3
gene id: 29088:ORMDL3
uniprot id: A0A2Y9I702
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Interacts with SPTLC1.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling.

29088:GOLM2
gene id: 29088:GOLM2
uniprot id: A0A2Y9HHB3
uniprot id: A0A2Y9HNK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

29088:GALNT11
gene id: 29088:GALNT11
uniprot id: A0A2Y9HFK4
uniprot id: A0A2Y9HGF0
uniprot id: A0A8M1MPV3
uniprot id: A0A8M1MT41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:ROR2
gene id: 29088:ROR2
uniprot id: A0A8M1MR57
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:MAOB
gene id: 29088:MAOB
uniprot id: A0A8M1M8J0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flavin monoamine oxidase family.
messages: Mitochondrion outer membrane
messages: Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer.

29088:LOC110576470
gene id: 29088:LOC110576470
uniprot id: A0A2Y9GTZ3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TUBB4B
gene id: 29088:TUBB4B
uniprot id: A0A2Y9HAA2
uniprot id: A0A8M1MRC5
uniprot id: A0A8M1MRD5
uniprot id: A0A8M1MUL3
uniprot id: A0A8M1MYH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

29088:LOC110577209
gene id: 29088:LOC110577209
uniprot id: A0A8M1M1I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

29088:CDK5RAP2
gene id: 29088:CDK5RAP2
uniprot id: A0A8M1MVH8
names: Subcellular Location Annotation
messages: centrosome

29088:NKX2-2
gene id: 29088:NKX2-2
uniprot id: A0A2Y9I4B6
names: Subcellular Location Annotation
messages: Nucleus

29088:LYRM9
gene id: 29088:LYRM9
uniprot id: A0A2Y9IF49
names: Similarity
messages: Belongs to the complex I LYR family. LYRM9 subfamily.

29088:KCNB1
gene id: 29088:KCNB1
uniprot id: A0A2Y9GWF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.1/KCNB1 sub-subfamily.
messages: Lateral cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: sarcolemma
messages: synaptosome

29088:FAM216B
gene id: 29088:FAM216B
uniprot id: A0A2Y9HW83
names: Similarity
messages: Belongs to the FAM216 family.

29088:BEX5
gene id: 29088:BEX5
uniprot id: A0A2Y9HPJ7
names: Similarity
messages: Belongs to the BEX family.

29088:MED16
gene id: 29088:MED16
uniprot id: A0A8M1MKP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 16 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

29088:MCOLN3
gene id: 29088:MCOLN3
uniprot id: A0A8M1MBS7
uniprot id: A0A8M1MGB9
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

29088:CD109
gene id: 29088:CD109
uniprot id: A0A8M1MH32
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.

29088:USO1
gene id: 29088:USO1
uniprot id: A0A2Y9I6X4
uniprot id: A0A2Y9I905
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VDP/USO1/EDE1 family.
messages: Membrane

29088:WNT5B
gene id: 29088:WNT5B
uniprot id: A0A2Y9H3V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

29088:NPTX2
gene id: 29088:NPTX2
uniprot id: A0A2Y9GDN8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:EPHB2
gene id: 29088:EPHB2
uniprot id: A0A2Y9GMS1
names: Subcellular Location Annotation
messages: Membrane

29088:TDRD5
gene id: 29088:TDRD5
uniprot id: A0A2Y9GGJ5
uniprot id: A0A2Y9GGP0
uniprot id: A0A2Y9GJW2
uniprot id: A0A2Y9GLL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDRD5 family.
messages: Cytoplasm
messages: Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly.

29088:LOC110577471
gene id: 29088:LOC110577471
uniprot id: A0A2Y9GTD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:NUP93
gene id: 29088:NUP93
uniprot id: A0A2Y9IBW7
uniprot id: A0A2Y9IC23
uniprot id: A0A8M1M0I2
uniprot id: A0A8M1M324
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: Nucleus envelope
messages: Nucleus membrane
messages: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.
messages: nuclear pore complex

29088:TFAP2E
gene id: 29088:TFAP2E
uniprot id: A0A8M1MG14
names: Similarity
messages: Belongs to the AP-2 family.

29088:TRAPPC3
gene id: 29088:TRAPPC3
uniprot id: A0A2Y9GPV7
uniprot id: A0A8M1MA56
uniprot id: A0A8M1MG19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

29088:FBXO25
gene id: 29088:FBXO25
uniprot id: A0A2Y9HDV6
uniprot id: A0A2Y9HJZ6
uniprot id: A0A2Y9HKB3
names: Subcellular Location Annotation
messages: Nucleus

29088:GARS1
gene id: 29088:GARS1
uniprot id: A0A2Y9H1Q7
uniprot id: A0A2Y9H6L2
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

29088:DDR1
gene id: 29088:DDR1
uniprot id: A0A8M1MH86
names: Subcellular Location Annotation
messages: Membrane

29088:CIBAR1
gene id: 29088:CIBAR1
uniprot id: A0A2Y9H1J9
uniprot id: A0A8M1M8J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIBAR family.
messages: centriole
messages: cilium basal body

29088:STAC3
gene id: 29088:STAC3
uniprot id: A0A2Y9GUN8
names: Subcellular Location Annotation
messages: sarcolemma

29088:LOC110573105
gene id: 29088:LOC110573105
uniprot id: A0A2Y9GDW3
names: Similarity
messages: Belongs to the KHDC1 family.

29088:CPEB3
gene id: 29088:CPEB3
uniprot id: A0A2Y9HV79
uniprot id: A0A2Y9HV83
uniprot id: A0A8M1MIN2
names: Similarity
messages: Belongs to the RRM CPEB family.

29088:SAR1A
gene id: 29088:SAR1A
uniprot id: A0A2Y9HZ47
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

29088:HLX
gene id: 29088:HLX
uniprot id: A0A2Y9HR71
names: Subcellular Location Annotation
messages: Nucleus

29088:MFSD1
gene id: 29088:MFSD1
uniprot id: A0A8M1MD32
uniprot id: A0A8M1MD37
names: Subcellular Location Annotation
messages: Membrane

29088:ARGLU1
gene id: 29088:ARGLU1
uniprot id: A0A2Y9HJ28
uniprot id: A0A2Y9HQD1
uniprot id: A0A8M1M8V3
names: Similarity
messages: Belongs to the UPF0430 family.

29088:IFT43
gene id: 29088:IFT43
uniprot id: A0A2Y9G8J6
names: Similarity
messages: Belongs to the IFT43 family.

29088:STRIP2
gene id: 29088:STRIP2
uniprot id: A0A2Y9HTZ1
names: Similarity
messages: Belongs to the STRIP family.

29088:PKP1
gene id: 29088:PKP1
uniprot id: A0A2Y9GLY4
names: Similarity
messages: Belongs to the beta-catenin family.

29088:NCK1
gene id: 29088:NCK1
uniprot id: A0A2Y9G8E2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

29088:CREB5
gene id: 29088:CREB5
uniprot id: A0A2Y9H1S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

29088:ATM
gene id: 29088:ATM
uniprot id: A0A2Y9HQS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: Cytoplasmic vesicle
messages: Nucleus
messages: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9, UBQLN4 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response. Phosphorylates ERCC6 which is essential for its chromatin remodeling activity at DNA double-strand breaks.

29088:RIMKLA
gene id: 29088:RIMKLA
uniprot id: A0A8M1MBK9
names: Similarity
messages: Belongs to the RimK family.

29088:SLC9A3
gene id: 29088:SLC9A3
uniprot id: A0A2Y9GU23
uniprot id: A0A2Y9GU84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Membrane

29088:UGP2
gene id: 29088:UGP2
uniprot id: A0A2Y9HTA4
uniprot id: A0A2Y9HTA9
uniprot id: A0A2Y9HTC5
uniprot id: A0A2Y9HZR1
uniprot id: A0A8M1MPS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

29088:PEAR1
gene id: 29088:PEAR1
uniprot id: A0A8M1MH70
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:NFE2L1
gene id: 29088:NFE2L1
uniprot id: A0A2Y9I896
uniprot id: A0A2Y9I901
uniprot id: A0A2Y9I904
uniprot id: A0A2Y9ICY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. CNC subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

29088:MKRN2
gene id: 29088:MKRN2
uniprot id: A0A2Y9HG76
uniprot id: A0A2Y9HGM5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:BOD1
gene id: 29088:BOD1
uniprot id: A0A2Y9HR81
uniprot id: A0A2Y9HXP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BOD1 family.
messages: centrosome
messages: kinetochore

29088:PHKG2
gene id: 29088:PHKG2
uniprot id: A0A2Y9HWA0
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

29088:FGF7
gene id: 29088:FGF7
uniprot id: A0A2Y9HCW0
uniprot id: A0A8M1MIX7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

29088:LOC110575800
gene id: 29088:LOC110575800
uniprot id: A0A2Y9GMM3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:RGS4
gene id: 29088:RGS4
uniprot id: A0A2Y9HR57
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.

29088:LOC110586355
gene id: 29088:LOC110586355
uniprot id: A0A8M1MGA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

29088:GPX5
gene id: 29088:GPX5
uniprot id: A0A2Y9HTU3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

29088:RXFP2
gene id: 29088:RXFP2
uniprot id: A0A2Y9G721
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:LOC110576454
gene id: 29088:LOC110576454
uniprot id: A0A8M1MSL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Membrane
messages: Mitochondrion inner membrane

29088:MYOD1
gene id: 29088:MYOD1
uniprot id: A0A2Y9GUH1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: Nucleus

29088:DIAPH2
gene id: 29088:DIAPH2
uniprot id: A0A8M1M0Y9
names: Similarity
messages: Belongs to the formin homology family. Diaphanous subfamily.

29088:SLC6A19
gene id: 29088:SLC6A19
uniprot id: A0A2Y9H001
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

29088:SH3BGRL2
gene id: 29088:SH3BGRL2
uniprot id: A0A2Y9HC41
names: Similarity
messages: Belongs to the SH3BGR family.

29088:CMTM5
gene id: 29088:CMTM5
uniprot id: A0A8M1MN70
names: Subcellular Location Annotation
messages: Membrane

29088:CMPK2
gene id: 29088:CMPK2
uniprot id: A0A2Y9HP40
names: Similarity
messages: Belongs to the thymidylate kinase family.

29088:LOC123323265
gene id: 29088:LOC123323265
uniprot id: A0A8M1M837
names: Similarity
messages: Belongs to the CD225/Dispanin family.

29088:LOC110592974
gene id: 29088:LOC110592974
uniprot id: A0A2Y9I795
uniprot id: A0A2Y9I7J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

29088:MED21
gene id: 29088:MED21
uniprot id: A0A2Y9H8X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

29088:PMM1
gene id: 29088:PMM1
uniprot id: A0A2Y9GV54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

29088:SAXO2
gene id: 29088:SAXO2
uniprot id: A0A2Y9GBA7
names: Similarity
messages: Belongs to the FAM154 family.

29088:SUMF2
gene id: 29088:SUMF2
uniprot id: A0A2Y9HWX2
uniprot id: A0A2Y9HX39
uniprot id: A0A2Y9I3H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

29088:SUGP2
gene id: 29088:SUGP2
uniprot id: A0A2Y9GLC6
names: Subcellular Location Annotation
messages: Nucleus

29088:TPD52L2
gene id: 29088:TPD52L2
uniprot id: A0A2Y9G5T6
uniprot id: A0A2Y9G6Z5
uniprot id: A0A8M1ML82
uniprot id: A0A8M1ML84
uniprot id: A0A8M1ML87
uniprot id: A0A8M1ML89
uniprot id: A0A8M1MN90
uniprot id: A0A8M1MPJ5
uniprot id: A0A8M1MVE1
names: Similarity
messages: Belongs to the TPD52 family.

29088:PLA2G1B
gene id: 29088:PLA2G1B
uniprot id: A0A2Y9IAH5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

29088:MTERF2
gene id: 29088:MTERF2
uniprot id: A0A2Y9H1H1
names: Similarity
messages: Belongs to the mTERF family.

29088:LOC110577591
gene id: 29088:LOC110577591
uniprot id: A0A2Y9GTU4
names: Similarity
messages: Belongs to the actin family.

29088:PKIB
gene id: 29088:PKIB
uniprot id: A0A2Y9HBZ4
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

29088:RGS8
gene id: 29088:RGS8
uniprot id: A0A2Y9GJT8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: Perikaryon
messages: dendrite

29088:HOXA5
gene id: 29088:HOXA5
uniprot id: A0A2Y9H5K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

29088:LOC110570640
gene id: 29088:LOC110570640
uniprot id: A0A8M1M3J5
names: Similarity
messages: Belongs to the SNF7 family.

29088:PTHLH
gene id: 29088:PTHLH
uniprot id: A0A2Y9H3Z5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the parathyroid hormone family.
messages: Cytoplasm
messages: Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Up-regulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath.
messages: Nucleus
messages: Osteostatin is a potent inhibitor of osteoclastic bone resorption.
messages: PTHrP interacts with PTH1R (via N-terminal extracellular domain).
messages: Secreted
messages: There are several secretory forms, including osteostatin, arising from endoproteolytic cleavage of the initial translation product. Each of these secretory forms is believed to have one or more of its own receptors that mediates the normal paracrine, autocrine and endocrine actions.

29088:GPR52
gene id: 29088:GPR52
uniprot id: A0A2Y9GH88
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

29088:MESD
gene id: 29088:MESD
uniprot id: A0A2Y9GB67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MESD family.
messages: Endoplasmic reticulum

29088:TSG101
gene id: 29088:TSG101
uniprot id: A0A2Y9GQK6
uniprot id: A0A8M1MWV1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

29088:LOC110578029
gene id: 29088:LOC110578029
uniprot id: A0A8M1MA52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

29088:ANGPTL4
gene id: 29088:ANGPTL4
uniprot id: A0A2Y9IB78
uniprot id: A0A8M1MK47
names: Subcellular Location Annotation
messages: Secreted

29088:PTPRD
gene id: 29088:PTPRD
uniprot id: A0A8M1MS58
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

29088:SCN7A
gene id: 29088:SCN7A
uniprot id: A0A2Y9IAW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

29088:LOC110571810
gene id: 29088:LOC110571810
uniprot id: A0A2Y9G9G4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

29088:SLC26A11
gene id: 29088:SLC26A11
uniprot id: A0A2Y9GBV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Cell membrane
messages: Membrane

29088:P4HA2
gene id: 29088:P4HA2
uniprot id: A0A2Y9I0R2
uniprot id: A0A2Y9I0R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

29088:CLASP2
gene id: 29088:CLASP2
uniprot id: A0A2Y9G2E8
uniprot id: A0A8M1MSA2
uniprot id: A0A8M1MSA6
uniprot id: A0A8M1MSC3
uniprot id: A0A8M1MSD3
uniprot id: A0A8M1MSE5
uniprot id: A0A8M1MU68
uniprot id: A0A8M1MU91
uniprot id: A0A8M1MVK9
uniprot id: A0A8M1MVL8
uniprot id: A0A8M1MYP2
uniprot id: A0A8M1MYP3
uniprot id: A0A8M1MYP5
uniprot id: A0A8M1MYQ1
uniprot id: A0A8M1MYQ2
names: Subcellular Location Annotation
messages: kinetochore

29088:PCID2
gene id: 29088:PCID2
uniprot id: A0A2Y9HPW5
uniprot id: A0A2Y9HQJ9
uniprot id: A0A8M1M6D9
uniprot id: A0A8M1M6P3
uniprot id: A0A8M1M8U0
names: Similarity
messages: Belongs to the CSN12 family.

29088:CEP63
gene id: 29088:CEP63
uniprot id: A0A2Y9G5Z2
uniprot id: A0A8M1MFX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP63 family.
messages: centriolar satellite

29088:ZCCHC8
gene id: 29088:ZCCHC8
uniprot id: A0A8M1MT70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC8 family.
messages: nucleoplasm

29088:SDC4
gene id: 29088:SDC4
uniprot id: A0A2Y9GZ30
uniprot id: A0A2Y9H3S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Membrane

29088:CCL5
gene id: 29088:CCL5
uniprot id: A0A2Y9I7X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

29088:CTPS2
gene id: 29088:CTPS2
uniprot id: A0A2Y9GC32
uniprot id: A0A8M1M116
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

29088:POU2F2
gene id: 29088:POU2F2
uniprot id: A0A8M1MVN8
uniprot id: A0A8M1MVP1
uniprot id: A0A8M1MVP3
uniprot id: A0A8M1MVP6
uniprot id: A0A8M1MX58
uniprot id: A0A8M1MX61
uniprot id: A0A8M1MXW0
uniprot id: A0A8M1MZD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus
messages: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR.

29088:TMEM39B
gene id: 29088:TMEM39B
uniprot id: A0A2Y9GPQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

29088:TIMP4
gene id: 29088:TIMP4
uniprot id: A0A2Y9HN42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: Secreted

29088:CD93
gene id: 29088:CD93
uniprot id: A0A2Y9I2E9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:NDUFB6
gene id: 29088:NDUFB6
uniprot id: A0A2Y9HCJ3
uniprot id: A0A2Y9HDS8
uniprot id: A0A8M1MS82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB6 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

29088:LOC110593448
gene id: 29088:LOC110593448
uniprot id: A0A2Y9I9H3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

29088:RNASE10
gene id: 29088:RNASE10
uniprot id: A0A2Y9HNW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

29088:PDGFRL
gene id: 29088:PDGFRL
uniprot id: A0A2Y9HJU6
names: Subcellular Location Annotation
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.
messages: Secreted

29088:ZNF174
gene id: 29088:ZNF174
uniprot id: A0A2Y9HQJ0
uniprot id: A0A8M1MCF1
names: Subcellular Location Annotation
messages: Nucleus

29088:SPIB
gene id: 29088:SPIB
uniprot id: A0A2Y9GHY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

29088:LOC110588117
gene id: 29088:LOC110588117
uniprot id: A0A8M1MLX6
names: Similarity
messages: Belongs to the PA28 family.

29088:MAPK9
gene id: 29088:MAPK9
uniprot id: A0A8M1MPJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

29088:LOC110591980
gene id: 29088:LOC110591980
uniprot id: A0A8M1M884
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

29088:FANCM
gene id: 29088:FANCM
uniprot id: A0A2Y9HZK2
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.

29088:MAN2A1
gene id: 29088:MAN2A1
uniprot id: A0A2Y9I4J9
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

29088:LOC110576124
gene id: 29088:LOC110576124
uniprot id: A0A2Y9GSR3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:SLC2A12
gene id: 29088:SLC2A12
uniprot id: A0A2Y9HIK1
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

29088:SLC29A4
gene id: 29088:SLC29A4
uniprot id: A0A2Y9G9S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

29088:RNASE13
gene id: 29088:RNASE13
uniprot id: A0A2Y9HI08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

29088:CDK1
gene id: 29088:CDK1
uniprot id: A0A2Y9HV46
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:VPS51
gene id: 29088:VPS51
uniprot id: A0A2Y9GPW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS51 family.
messages: Component of the Golgi-associated retrograde protein (GARP) complex. Component of the endosome-associated retrograde protein (EARP) complex.
messages: Endosome
messages: Involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. Acts as component of the EARP complex that is involved in endocytic recycling.
messages: Recycling endosome
messages: trans-Golgi network

29088:LOC110578978
gene id: 29088:LOC110578978
uniprot id: A0A8M1MCE8
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

29088:SNX10
gene id: 29088:SNX10
uniprot id: A0A2Y9H132
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

29088:GDAP1L1
gene id: 29088:GDAP1L1
uniprot id: A0A2Y9GZM9
uniprot id: A0A2Y9GZS9
uniprot id: A0A2Y9GZU1
uniprot id: A0A2Y9H494
uniprot id: A0A2Y9H670
names: Similarity
messages: Belongs to the GST superfamily.

29088:PPT1
gene id: 29088:PPT1
uniprot id: A0A2Y9GK16
uniprot id: A0A8M1MG44
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

29088:LOC110593592
gene id: 29088:LOC110593592
uniprot id: A0A2Y9IDT8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:CASP8
gene id: 29088:CASP8
uniprot id: A0A2Y9I959
names: Similarity
messages: Belongs to the peptidase C14A family.

29088:PTGES
gene id: 29088:PTGES
uniprot id: A0A2Y9H6S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

29088:LOC123326212
gene id: 29088:LOC123326212
uniprot id: A0A8M1MXN3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:TULP1
gene id: 29088:TULP1
uniprot id: A0A2Y9GM63
uniprot id: A0A2Y9GR03
names: Similarity
messages: Belongs to the TUB family.

29088:FXYD2
gene id: 29088:FXYD2
uniprot id: A0A2Y9HKC8
names: Similarity
messages: Belongs to the FXYD family.

29088:PTCD2
gene id: 29088:PTCD2
uniprot id: A0A2Y9I317
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTCD2 family.
messages: Mitochondrion

29088:DYNC2LI1
gene id: 29088:DYNC2LI1
uniprot id: A0A2Y9I3Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light intermediate chain family.
messages: centrosome
messages: cilium
messages: cilium axoneme
messages: cilium basal body

29088:NR0B2
gene id: 29088:NR0B2
uniprot id: A0A2Y9GJC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

29088:LOC110590886
gene id: 29088:LOC110590886
uniprot id: A0A8M1M6L8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

29088:RIPOR3
gene id: 29088:RIPOR3
uniprot id: A0A2Y9GQX1
names: Similarity
messages: Belongs to the RIPOR family.

29088:ADAMTS19
gene id: 29088:ADAMTS19
uniprot id: A0A2Y9I5R3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:AQP9
gene id: 29088:AQP9
uniprot id: A0A2Y9HCR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

29088:ENGASE
gene id: 29088:ENGASE
uniprot id: A0A2Y9GG53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 85 family.
messages: cytosol

29088:MYLK
gene id: 29088:MYLK
uniprot id: A0A8M1MXW6
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

29088:FERMT2
gene id: 29088:FERMT2
uniprot id: A0A2Y9I6M2
uniprot id: A0A8M1MKG7
names: Similarity
messages: Belongs to the kindlin family.

29088:PLD2
gene id: 29088:PLD2
uniprot id: A0A2Y9HLH0
uniprot id: A0A8M1MX08
names: Similarity
messages: Belongs to the phospholipase D family.

29088:ATG13
gene id: 29088:ATG13
uniprot id: A0A2Y9GPG0
uniprot id: A0A2Y9GTB2
uniprot id: A0A8M1MMJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
messages: Belongs to the ATG13 family. Metazoan subfamily.
messages: Preautophagosomal structure

29088:GPRC6A
gene id: 29088:GPRC6A
uniprot id: A0A2Y9HBV0
uniprot id: A0A2Y9HC12
uniprot id: A0A2Y9HC86
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:CCN3
gene id: 29088:CCN3
uniprot id: A0A2Y9H480
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:LOC110571911
gene id: 29088:LOC110571911
uniprot id: A0A2Y9GCH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

29088:SPSB2
gene id: 29088:SPSB2
uniprot id: A0A2Y9H495
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

29088:FAT1
gene id: 29088:FAT1
uniprot id: A0A2Y9HDF8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:GNG7
gene id: 29088:GNG7
uniprot id: A0A8M1MPE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

29088:LOC110594297
gene id: 29088:LOC110594297
uniprot id: A0A2Y9IBZ2
uniprot id: A0A2Y9ICU6
names: Similarity
messages: Belongs to the UPF0547 family.

29088:POLE
gene id: 29088:POLE
uniprot id: A0A2Y9H8D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Nucleus

29088:SLC12A5
gene id: 29088:SLC12A5
uniprot id: A0A2Y9H4I8
uniprot id: A0A2Y9H6G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

29088:ODF2L
gene id: 29088:ODF2L
uniprot id: A0A2Y9H2G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

29088:ACOT4
gene id: 29088:ACOT4
uniprot id: A0A2Y9G8C0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

29088:VASN
gene id: 29088:VASN
uniprot id: A0A2Y9HQY4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SLC5A12
gene id: 29088:SLC5A12
uniprot id: A0A2Y9GUL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

29088:HTR1E
gene id: 29088:HTR1E
uniprot id: A0A2Y9HCC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:MTFR1L
gene id: 29088:MTFR1L
uniprot id: A0A8M1M7T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

29088:LOC110590940
gene id: 29088:LOC110590940
uniprot id: A0A2Y9GKD4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL28 family.

29088:AOC2
gene id: 29088:AOC2
uniprot id: A0A2Y9GJ03
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

29088:SDR16C5
gene id: 29088:SDR16C5
uniprot id: A0A2Y9GX89
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

29088:ITGA10
gene id: 29088:ITGA10
uniprot id: A0A2Y9GWQ1
uniprot id: A0A2Y9GX06
uniprot id: A0A2Y9GX31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

29088:CENPH
gene id: 29088:CENPH
uniprot id: A0A8M1MQ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-H/MCM16 family.
messages: Nucleus
messages: kinetochore

29088:SEMA5A
gene id: 29088:SEMA5A
uniprot id: A0A2Y9I7D3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:AADACL2
gene id: 29088:AADACL2
uniprot id: A0A2Y9GR31
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

29088:PAMR1
gene id: 29088:PAMR1
uniprot id: A0A2Y9GME4
uniprot id: A0A2Y9GRF2
uniprot id: A0A2Y9GT44
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110571842
gene id: 29088:LOC110571842
uniprot id: A0A2Y9G9I7
uniprot id: A0A2Y9G9Q7
uniprot id: A0A8M1M9K3
uniprot id: A0A8M1MD30
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

29088:LOC110591928
gene id: 29088:LOC110591928
uniprot id: A0A8M1M889
names: Caution
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK. The mature dimeric form interacts with PPP1R16B (via its fourth ankyrin repeat). Interacts with PPP1CA only in the presence of PPP1R16B.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

29088:NR1D2
gene id: 29088:NR1D2
uniprot id: A0A2Y9G8J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

29088:FUT10
gene id: 29088:FUT10
uniprot id: A0A2Y9HDW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Predominantly fucosylates the innermost N-acetyl glucosamine (GlcNAc) residue in biantennary N-glycan acceptors.

29088:CUTA
gene id: 29088:CUTA
uniprot id: A0A2Y9GM41
uniprot id: A0A2Y9GQX5
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

29088:LOC110589372
gene id: 29088:LOC110589372
uniprot id: A0A8M1MDP3
names: Similarity
messages: Belongs to the COX20 family.

29088:LOC110580915
gene id: 29088:LOC110580915
uniprot id: A0A2Y9H3T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:CHST9
gene id: 29088:CHST9
uniprot id: A0A2Y9GRW4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:CDH9
gene id: 29088:CDH9
uniprot id: A0A2Y9HIF5
uniprot id: A0A2Y9HPG8
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

29088:NFXL1
gene id: 29088:NFXL1
uniprot id: A0A2Y9I6U4
names: Similarity
messages: Belongs to the NFX1 family.

29088:LOC110581513
gene id: 29088:LOC110581513
uniprot id: A0A2Y9H625
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:PPM1N
gene id: 29088:PPM1N
uniprot id: A0A2Y9GGX7
names: Similarity
messages: Belongs to the PP2C family.

29088:EXOC3L2
gene id: 29088:EXOC3L2
uniprot id: A0A8M1M0A9
names: Similarity
messages: Belongs to the SEC6 family.

29088:FAM83F
gene id: 29088:FAM83F
uniprot id: A0A2Y9GVZ4
names: Similarity
messages: Belongs to the FAM83 family.

29088:LOC110580780
gene id: 29088:LOC110580780
uniprot id: A0A2Y9H3B9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:LPL
gene id: 29088:LPL
uniprot id: A0A2Y9HZF3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Homodimer. Interacts with APOC2; the interaction activates LPL activity in the presence of lipids.
messages: Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity.
messages: extracellular matrix

29088:C5H12orf57
gene id: 29088:C5H12orf57
uniprot id: A0A2Y9HAV7
uniprot id: A0A8M1MC74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0456 family.
messages: Cytoplasm

29088:LOC110577351
gene id: 29088:LOC110577351
uniprot id: A0A2Y9GWV2
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

29088:PLXNA3
gene id: 29088:PLXNA3
uniprot id: A0A8M1M1T4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:NXPH1
gene id: 29088:NXPH1
uniprot id: A0A2Y9H7Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

29088:KLC2
gene id: 29088:KLC2
uniprot id: A0A2Y9GNA5
uniprot id: A0A2Y9GNM2
uniprot id: A0A2Y9GU20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

29088:LRWD1
gene id: 29088:LRWD1
uniprot id: A0A2Y9HX28
uniprot id: A0A2Y9HXA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRWD1 family.
messages: centrosome
messages: kinetochore
messages: telomere

29088:OTX2
gene id: 29088:OTX2
uniprot id: A0A2Y9HZM0
uniprot id: A0A2Y9I033
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

29088:RPLP1
gene id: 29088:RPLP1
uniprot id: A0A2Y9HD41
uniprot id: A0A8M1MN99
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

29088:GLCE
gene id: 29088:GLCE
uniprot id: A0A2Y9HD06
uniprot id: A0A8M1MUN7
names: Similarity
messages: Belongs to the D-glucuronyl C5-epimerase family.

29088:LOC110593194
gene id: 29088:LOC110593194
uniprot id: A0A2Y9I7Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:VPS36
gene id: 29088:VPS36
uniprot id: A0A2Y9G4S5
uniprot id: A0A2Y9G590
uniprot id: A0A8M1MET1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

29088:LOC110592038
gene id: 29088:LOC110592038
uniprot id: A0A8M1MDX4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

29088:MRPL33
gene id: 29088:MRPL33
uniprot id: A0A2Y9HN03
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

29088:CACNA1H
gene id: 29088:CACNA1H
uniprot id: A0A8M1MFZ6
uniprot id: A0A8M1MKX8
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110577485
gene id: 29088:LOC110577485
uniprot id: A0A2Y9GXE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:CDK3
gene id: 29088:CDK3
uniprot id: A0A2Y9GC92
uniprot id: A0A2Y9GCD9
uniprot id: A0A2Y9GCF6
uniprot id: A0A2Y9GF67
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:G6PD
gene id: 29088:G6PD
uniprot id: A0A2Y9GHF1
uniprot id: A0A2Y9GKN6
uniprot id: A0A2Y9GME3
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.

29088:APOOL
gene id: 29088:APOOL
uniprot id: A0A2Y9HC28
uniprot id: A0A2Y9HD84
uniprot id: A0A8M1M914
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

29088:MYH9
gene id: 29088:MYH9
uniprot id: A0A2Y9GV38
uniprot id: A0A8M1MDY0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

29088:LOC110573999
gene id: 29088:LOC110573999
uniprot id: A0A2Y9GLN5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
messages: Nucleus

29088:LOC110588693
gene id: 29088:LOC110588693
uniprot id: A0A8M1MFW6
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

29088:FAM174A
gene id: 29088:FAM174A
uniprot id: A0A2Y9HSV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

29088:ART1
gene id: 29088:ART1
uniprot id: A0A2Y9I8T4
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

29088:RUVBL2
gene id: 29088:RUVBL2
uniprot id: A0A2Y9GD51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

29088:LOC110588398
gene id: 29088:LOC110588398
uniprot id: A0A8M1M928
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: cytoskeleton

29088:CARMIL1
gene id: 29088:CARMIL1
uniprot id: A0A2Y9HRZ1
uniprot id: A0A8M1MJA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

29088:MCF2L
gene id: 29088:MCF2L
uniprot id: A0A8M1MA81
uniprot id: A0A8M1MEL2
names: Subcellular Location Annotation
messages: Cytoplasm

29088:POU5F1
gene id: 29088:POU5F1
uniprot id: A0A2Y9HLV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-5 subfamily.
messages: Nucleus

29088:FHIP1A
gene id: 29088:FHIP1A
uniprot id: A0A2Y9HSG4
names: Similarity
messages: Belongs to the FHIP family.

29088:APLP1
gene id: 29088:APLP1
uniprot id: A0A2Y9HXS6
uniprot id: A0A2Y9HXU8
uniprot id: A0A2Y9HY40
uniprot id: A0A2Y9HY45
uniprot id: A0A2Y9I2R8
uniprot id: A0A8M1MVQ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:RPA2
gene id: 29088:RPA2
uniprot id: A0A2Y9GJE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 2 family.
messages: Nucleus

29088:ALDH7A1
gene id: 29088:ALDH7A1
uniprot id: A0A2Y9I584
uniprot id: A0A8M1MKE1
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

29088:ADGB
gene id: 29088:ADGB
uniprot id: A0A2Y9HHP5
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110573972
gene id: 29088:LOC110573972
uniprot id: A0A8M1MET3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

29088:CDC45
gene id: 29088:CDC45
uniprot id: A0A2Y9H4H2
uniprot id: A0A8M1MSM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

29088:LTA
gene id: 29088:LTA
uniprot id: A0A2Y9HLZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tumor necrosis factor family.
messages: Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
messages: Homotrimer, and heterotrimer of either two LTB and one LTA subunits or (less prevalent) two LTA and one LTB subunits. Interacts with TNFRSF14.
messages: Membrane
messages: Secreted

29088:PHACTR2
gene id: 29088:PHACTR2
uniprot id: A0A2Y9HB99
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

29088:DTNB
gene id: 29088:DTNB
uniprot id: A0A2Y9HNU2
uniprot id: A0A2Y9HP93
uniprot id: A0A2Y9HVM4
uniprot id: A0A8M1MLS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dystrophin family. Dystrobrevin subfamily.
messages: Cytoplasm

29088:SLC20A1
gene id: 29088:SLC20A1
uniprot id: A0A2Y9HMV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

29088:LOC110580381
gene id: 29088:LOC110580381
uniprot id: A0A2Y9H8X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

29088:LOC110590314
gene id: 29088:LOC110590314
uniprot id: A0A2Y9HYJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secretoglobin family.
messages: Secreted

29088:BCLAF1
gene id: 29088:BCLAF1
uniprot id: A0A2Y9HCC5
uniprot id: A0A2Y9HIU8
uniprot id: A0A8M1MSD2
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

29088:BBOX1
gene id: 29088:BBOX1
uniprot id: A0A2Y9GUS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-BBH/TMLD family.
messages: Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
messages: Cytoplasm

29088:IDUA
gene id: 29088:IDUA
uniprot id: A0A2Y9G2M1
uniprot id: A0A8M1M6T6
uniprot id: A0A8M1MCC4
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

29088:ITGB4
gene id: 29088:ITGB4
uniprot id: A0A8M1MTZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

29088:MTMR1
gene id: 29088:MTMR1
uniprot id: A0A2Y9GN21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

29088:AMACR
gene id: 29088:AMACR
uniprot id: A0A2Y9HIW8
uniprot id: A0A2Y9HQK8
names: Similarity
messages: Belongs to the CoA-transferase III family.

29088:ALX3
gene id: 29088:ALX3
uniprot id: A0A2Y9H2T0
names: Subcellular Location Annotation
messages: Nucleus

29088:PASK
gene id: 29088:PASK
uniprot id: A0A2Y9G725
names: Similarity
messages: Belongs to the mTERF family.

29088:LOC110592672
gene id: 29088:LOC110592672
uniprot id: A0A8M1MYC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zona pellucida-binding protein Sp38 family.
messages: Secreted

29088:SERPINE1
gene id: 29088:SERPINE1
uniprot id: A0A2Y9HFJ9
names: Similarity
messages: Belongs to the serpin family.

29088:NRDE2
gene id: 29088:NRDE2
uniprot id: A0A2Y9G8Z8
names: Similarity
messages: Belongs to the NRDE2 family.

29088:MGAT2
gene id: 29088:MGAT2
uniprot id: A0A2Y9HZP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 16 (GT16) protein family.
messages: Golgi apparatus membrane
messages: Membrane

29088:LOC110593220
gene id: 29088:LOC110593220
uniprot id: A0A8M1MV06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

29088:IL1R1
gene id: 29088:IL1R1
uniprot id: A0A2Y9GEF3
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

29088:BHLHB9
gene id: 29088:BHLHB9
uniprot id: A0A2Y9H881
names: Similarity
messages: Belongs to the GPRASP family.

29088:KCNJ16
gene id: 29088:KCNJ16
uniprot id: A0A2Y9G8P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

29088:LOC110576492
gene id: 29088:LOC110576492
uniprot id: A0A2Y9GQ99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110578952
gene id: 29088:LOC110578952
uniprot id: A0A2Y9GY62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

29088:DYNLRB2
gene id: 29088:DYNLRB2
uniprot id: A0A2Y9IA90
names: Similarity
messages: Belongs to the GAMAD family.

29088:ADAM23
gene id: 29088:ADAM23
uniprot id: A0A8M1M624
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SPDL1
gene id: 29088:SPDL1
uniprot id: A0A2Y9HWR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Spindly family.
messages: Interacts with KNTC1 and ZW10. These interactions appear weak and may be transient or indirect.
messages: Nucleus
messages: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.
messages: centrosome
messages: kinetochore
messages: spindle pole

29088:LOC110582499
gene id: 29088:LOC110582499
uniprot id: A0A2Y9H953
names: Similarity
messages: Belongs to the CKAP2 family.

29088:INPP5K
gene id: 29088:INPP5K
uniprot id: A0A2Y9I844
uniprot id: A0A2Y9I8W5
uniprot id: A0A2Y9IFK0
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

29088:HGH1
gene id: 29088:HGH1
uniprot id: A0A2Y9H2L7
names: Similarity
messages: Belongs to the HGH1 family.

29088:LOC110579734
gene id: 29088:LOC110579734
uniprot id: A0A2Y9H0G3
uniprot id: A0A2Y9H585
uniprot id: A0A2Y9H6Z6
uniprot id: A0A8M1MRX1
uniprot id: A0A8M1MRX6
uniprot id: A0A8M1MRY1
uniprot id: A0A8M1MRY2
uniprot id: A0A8M1MRY7
uniprot id: A0A8M1MRZ2
uniprot id: A0A8M1MTS9
uniprot id: A0A8M1MTT9
uniprot id: A0A8M1MTU4
uniprot id: A0A8M1MV59
uniprot id: A0A8M1MV64
uniprot id: A0A8M1MV69
uniprot id: A0A8M1MYL9
uniprot id: A0A8M1MYM0
uniprot id: A0A8M1MYM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

29088:DCBLD2
gene id: 29088:DCBLD2
uniprot id: A0A2Y9GWR0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:PPIP5K2
gene id: 29088:PPIP5K2
uniprot id: A0A2Y9HZQ1
uniprot id: A0A2Y9HZT4
uniprot id: A0A2Y9I008
uniprot id: A0A2Y9I017
uniprot id: A0A2Y9I082
uniprot id: A0A2Y9I086
uniprot id: A0A2Y9I0B0
uniprot id: A0A2Y9I4T0
uniprot id: A0A8M1MGN7
uniprot id: A0A8M1MGN9
uniprot id: A0A8M1MGP2
uniprot id: A0A8M1MGP3
uniprot id: A0A8M1MIR7
uniprot id: A0A8M1MIS2
uniprot id: A0A8M1MK34
uniprot id: A0A8M1MQI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

29088:GUCY2C
gene id: 29088:GUCY2C
uniprot id: A0A2Y9H8F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

29088:CSF3
gene id: 29088:CSF3
uniprot id: A0A2Y9ICI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
messages: Secreted

29088:MTNR1A
gene id: 29088:MTNR1A
uniprot id: A0A2Y9HK49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
messages: Membrane

29088:VAMP5
gene id: 29088:VAMP5
uniprot id: A0A2Y9HNK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

29088:LOC110587810
gene id: 29088:LOC110587810
uniprot id: A0A2Y9HPK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:LOC110580771
gene id: 29088:LOC110580771
uniprot id: A0A2Y9H3A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

29088:C1D
gene id: 29088:C1D
uniprot id: A0A2Y9HZL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the C1D family.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Nucleus
messages: Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
messages: nucleolus

29088:LOC110580711
gene id: 29088:LOC110580711
uniprot id: A0A2Y9H371
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

29088:DSG3
gene id: 29088:DSG3
uniprot id: A0A2Y9GRA7
uniprot id: A0A2Y9GRD6
uniprot id: A0A2Y9GV66
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

29088:HTR2C
gene id: 29088:HTR2C
uniprot id: A0A2Y9GS57
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MPDZ. Interacts with ARRB2.
messages: Membrane

29088:BCL2L2
gene id: 29088:BCL2L2
uniprot id: A0A2Y9HNR7
names: Similarity
messages: Belongs to the Bcl-2 family.

29088:FXN
gene id: 29088:FXN
uniprot id: A0A2Y9HKI6
names: Similarity
messages: Belongs to the frataxin family.

29088:JPH4
gene id: 29088:JPH4
uniprot id: A0A2Y9HHH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

29088:MARS2
gene id: 29088:MARS2
uniprot id: A0A2Y9I9D0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

29088:SUB1
gene id: 29088:SUB1
uniprot id: A0A2Y9HJ33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Homodimer. Interacts with CSTF2.
messages: Nucleus

29088:BTN1A1
gene id: 29088:BTN1A1
uniprot id: A0A2Y9HLH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

29088:LOC110576773
gene id: 29088:LOC110576773
uniprot id: A0A2Y9GQT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

29088:LOC110580324
gene id: 29088:LOC110580324
uniprot id: A0A2Y9H278
uniprot id: A0A8M1MAF2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

29088:TAF4
gene id: 29088:TAF4
uniprot id: A0A2Y9G3V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

29088:PDYN
gene id: 29088:PDYN
uniprot id: A0A2Y9H4X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin.
messages: Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Leumorphin has a typical opiod activity and may have anti-apoptotic effect.
messages: Secreted

29088:PGGT1B
gene id: 29088:PGGT1B
uniprot id: A0A2Y9I0N3
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

29088:MMD2
gene id: 29088:MMD2
uniprot id: A0A2Y9GCC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

29088:TBRG1
gene id: 29088:TBRG1
uniprot id: A0A2Y9HJV0
names: Subcellular Location Annotation
messages: Nucleus

29088:MINAR1
gene id: 29088:MINAR1
uniprot id: A0A2Y9GB71
names: Similarity
messages: Belongs to the MINAR family.

29088:TSPYL6
gene id: 29088:TSPYL6
uniprot id: A0A2Y9HZA9
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

29088:ATAD2B
gene id: 29088:ATAD2B
uniprot id: A0A2Y9HTI7
uniprot id: A0A8M1MNB1
names: Similarity
messages: Belongs to the AAA ATPase family.

29088:NAALAD2
gene id: 29088:NAALAD2
uniprot id: A0A2Y9G6V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

29088:SMC1B
gene id: 29088:SMC1B
uniprot id: A0A2Y9GWA4
uniprot id: A0A2Y9H270
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

29088:RYR2
gene id: 29088:RYR2
uniprot id: A0A2Y9HJI5
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

29088:PCSK6
gene id: 29088:PCSK6
uniprot id: A0A2Y9GE37
uniprot id: A0A2Y9GFM4
names: Similarity
messages: Belongs to the peptidase S8 family.

29088:DGKZ
gene id: 29088:DGKZ
uniprot id: A0A2Y9GPJ0
uniprot id: A0A2Y9GTA7
uniprot id: A0A2Y9GUZ0
uniprot id: A0A2Y9GUZ5
uniprot id: A0A8M1MPI2
uniprot id: A0A8M1MPJ2
uniprot id: A0A8M1MRF1
uniprot id: A0A8M1MST2
uniprot id: A0A8M1MXZ3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

29088:OPRK1
gene id: 29088:OPRK1
uniprot id: A0A2Y9GXJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
messages: Interacts with SLC9A3R1. Interacts with GABARAPL1.
messages: Membrane

29088:LOC110576826
gene id: 29088:LOC110576826
uniprot id: A0A2Y9GV27
uniprot id: A0A8M1M1K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

29088:LOC110581679
gene id: 29088:LOC110581679
uniprot id: A0A2Y9H6H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:AGTR2
gene id: 29088:AGTR2
uniprot id: A0A2Y9GS84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MTUS1.
messages: Membrane

29088:EEF2
gene id: 29088:EEF2
uniprot id: A0A2Y9IAV0
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

29088:DMRTA2
gene id: 29088:DMRTA2
uniprot id: A0A2Y9GQH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

29088:IL26
gene id: 29088:IL26
uniprot id: A0A2Y9G5I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

29088:MYRF
gene id: 29088:MYRF
uniprot id: A0A2Y9GMV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRF family.
messages: Membrane

29088:LOC110574913
gene id: 29088:LOC110574913
uniprot id: A0A8M1M518
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS21 family.

29088:TRMT2A
gene id: 29088:TRMT2A
uniprot id: A0A2Y9H9T2
uniprot id: A0A8M1MTP1
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:GPM6A
gene id: 29088:GPM6A
uniprot id: A0A2Y9HJR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

29088:BMPR1B
gene id: 29088:BMPR1B
uniprot id: A0A2Y9GDC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

29088:LOC110581603
gene id: 29088:LOC110581603
uniprot id: A0A2Y9H6F2
uniprot id: A0A8M1MRM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:MED28
gene id: 29088:MED28
uniprot id: A0A2Y9G7P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 28 family.
messages: Nucleus

29088:PLPPR4
gene id: 29088:PLPPR4
uniprot id: A0A2Y9H904
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

29088:GSTK1
gene id: 29088:GSTK1
uniprot id: A0A2Y9HFM0
uniprot id: A0A2Y9HGG5
uniprot id: A0A8M1MRR4
names: Similarity
messages: Belongs to the GST superfamily. Kappa family.

29088:LOC110572605
gene id: 29088:LOC110572605
uniprot id: A0A8M1M986
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Component of the 60S subunit of the ribosome. Ribosomal protein L40 is essential for translation of a subset of cellular transcripts, and especially for cap-dependent translation of vesicular stomatitis virus mRNAs.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus
messages: Ribosomal protein L40 is part of the 60S ribosomal subunit. Interacts with UBQLN1 (via UBA domain).

29088:TSEN15
gene id: 29088:TSEN15
uniprot id: A0A2Y9GGM7
uniprot id: A0A8M1MI79
names: Similarity
messages: Belongs to the SEN15 family.

29088:TRAM1L1
gene id: 29088:TRAM1L1
uniprot id: A0A2Y9GM10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

29088:CFL2
gene id: 29088:CFL2
uniprot id: A0A2Y9HNL0
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

29088:CFD
gene id: 29088:CFD
uniprot id: A0A2Y9IF68
uniprot id: A0A8M1MMJ0
names: Function
messages: Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.

29088:LOC110593176
gene id: 29088:LOC110593176
uniprot id: A0A8M1MWU9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

29088:GATM
gene id: 29088:GATM
uniprot id: A0A2Y9HHX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the amidinotransferase family.
messages: Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine.
messages: Homodimer.
messages: Mitochondrion inner membrane

29088:CHMP4B
gene id: 29088:CHMP4B
uniprot id: A0A2Y9GZF0
names: Similarity
messages: Belongs to the SNF7 family.

29088:SNAP23
gene id: 29088:SNAP23
uniprot id: A0A2Y9HNH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

29088:SMPDL3B
gene id: 29088:SMPDL3B
uniprot id: A0A2Y9GS07
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

29088:ALG6
gene id: 29088:ALG6
uniprot id: A0A2Y9G9K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:SDHAF3
gene id: 29088:SDHAF3
uniprot id: A0A2Y9H1M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

29088:NAA60
gene id: 29088:NAA60
uniprot id: A0A2Y9HQ86
uniprot id: A0A2Y9HV22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA60 subfamily.
messages: Golgi apparatus membrane

29088:LOC110584708
gene id: 29088:LOC110584708
uniprot id: A0A2Y9HFY0
names: Subcellular Location Annotation
messages: Membrane

29088:CRYBG3
gene id: 29088:CRYBG3
uniprot id: A0A2Y9H0T3
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

29088:LOC110591501
gene id: 29088:LOC110591501
uniprot id: A0A8M1M6H4
names: Similarity
messages: Belongs to the ENTR1 family.

29088:IQCG
gene id: 29088:IQCG
uniprot id: A0A8M1MUY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC9 family.
messages: flagellum
messages: flagellum axoneme

29088:TRAPPC13
gene id: 29088:TRAPPC13
uniprot id: A0A2Y9I0I5
uniprot id: A0A2Y9I0U4
uniprot id: A0A2Y9I0U9
uniprot id: A0A2Y9I105
uniprot id: A0A2Y9I5H4
uniprot id: A0A2Y9I5I0
uniprot id: A0A2Y9I7G8
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

29088:FFAR3
gene id: 29088:FFAR3
uniprot id: A0A2Y9HY99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:ELOA
gene id: 29088:ELOA
uniprot id: A0A8M1M9R0
names: Subcellular Location Annotation
messages: Nucleus

29088:PIM2
gene id: 29088:PIM2
uniprot id: A0A2Y9G9Q8
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

29088:DLGAP5
gene id: 29088:DLGAP5
uniprot id: A0A2Y9I6F0
names: Similarity
messages: Belongs to the SAPAP family.

29088:LOC110587167
gene id: 29088:LOC110587167
uniprot id: A0A2Y9HN52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

29088:FOXP1
gene id: 29088:FOXP1
uniprot id: A0A2Y9HGH3
uniprot id: A0A2Y9HMM3
names: Subcellular Location Annotation
messages: Nucleus

29088:RBM47
gene id: 29088:RBM47
uniprot id: A0A2Y9I4Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM RBM47 family.
messages: Nucleus

29088:CD6
gene id: 29088:CD6
uniprot id: A0A2Y9GTI9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ZDHHC16
gene id: 29088:ZDHHC16
uniprot id: A0A2Y9HUF5
uniprot id: A0A2Y9HZA5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

29088:RPAP1
gene id: 29088:RPAP1
uniprot id: A0A2Y9HPB9
names: Similarity
messages: Belongs to the RPAP1 family.

29088:ST6GALNAC5
gene id: 29088:ST6GALNAC5
uniprot id: A0A2Y9G4K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

29088:PARP8
gene id: 29088:PARP8
uniprot id: A0A8M1MIC1
uniprot id: A0A8M1MQ29
names: Similarity
messages: Belongs to the ARTD/PARP family.

29088:INHBC
gene id: 29088:INHBC
uniprot id: A0A2Y9GUR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

29088:SPCS1
gene id: 29088:SPCS1
uniprot id: A0A2Y9HMY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:GLUD1
gene id: 29088:GLUD1
uniprot id: A0A2Y9I2T7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

29088:PBX4
gene id: 29088:PBX4
uniprot id: A0A8M1MKV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

29088:CCL17
gene id: 29088:CCL17
uniprot id: A0A2Y9I809
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

29088:ALDOC
gene id: 29088:ALDOC
uniprot id: A0A8M1MWX2
uniprot id: A0A8M1MZA3
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

29088:RER1
gene id: 29088:RER1
uniprot id: A0A2Y9HP32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

29088:DYNLT5
gene id: 29088:DYNLT5
uniprot id: A0A2Y9G9M5
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

29088:DDX41
gene id: 29088:DDX41
uniprot id: A0A2Y9HS57
uniprot id: A0A2Y9HXJ9
uniprot id: A0A2Y9HZ29
uniprot id: A0A8M1MFX1
uniprot id: A0A8M1MI02
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX41 subfamily.

29088:UTS2B
gene id: 29088:UTS2B
uniprot id: A0A2Y9H9E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

29088:HIBCH
gene id: 29088:HIBCH
uniprot id: A0A2Y9I540
uniprot id: A0A2Y9I9U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
messages: Mitochondrion

29088:LOC110594153
gene id: 29088:LOC110594153
uniprot id: A0A2Y9IFT9
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110576584
gene id: 29088:LOC110576584
uniprot id: A0A2Y9GW15
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:TOP2B
gene id: 29088:TOP2B
uniprot id: A0A2Y9G6E8
uniprot id: A0A8M1MYK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

29088:DEFB113
gene id: 29088:DEFB113
uniprot id: A0A2Y9HDK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

29088:C6
gene id: 29088:C6
uniprot id: A0A2Y9HKA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Component of the membrane attack complex (MAC). MAC assembly is initiated by proteolytic cleavage of C5 into C5a and C5b. C5b binds sequentially C6, C7, C8 and 12-14 copies of the pore-forming subunit C9.
messages: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:IRF4
gene id: 29088:IRF4
uniprot id: A0A2Y9HSG0
uniprot id: A0A2Y9HTP8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

29088:STAG3
gene id: 29088:STAG3
uniprot id: A0A2Y9G9Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

29088:FUBP1
gene id: 29088:FUBP1
uniprot id: A0A2Y9G471
uniprot id: A0A2Y9G488
uniprot id: A0A2Y9G493
uniprot id: A0A2Y9G4P2
uniprot id: A0A2Y9G7U7
uniprot id: A0A2Y9G7V2
uniprot id: A0A8M1M9D0
uniprot id: A0A8M1M9D5
uniprot id: A0A8M1M9L1
uniprot id: A0A8M1MBR1
uniprot id: A0A8M1MD40
uniprot id: A0A8M1MHT2
uniprot id: A0A8M1MHT7
names: Subcellular Location Annotation
messages: Nucleus

29088:TJP2
gene id: 29088:TJP2
uniprot id: A0A2Y9HKD7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

29088:FXYD6
gene id: 29088:FXYD6
uniprot id: A0A2Y9HJF5
uniprot id: A0A8M1MY15
names: Similarity
messages: Belongs to the FXYD family.

29088:GPR157
gene id: 29088:GPR157
uniprot id: A0A2Y9GKK8
names: Subcellular Location Annotation
messages: Membrane

29088:B4GALT5
gene id: 29088:B4GALT5
uniprot id: A0A2Y9GQX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

29088:GFRA3
gene id: 29088:GFRA3
uniprot id: A0A2Y9I634
names: Similarity
messages: Belongs to the GDNFR family.

29088:LHX4
gene id: 29088:LHX4
uniprot id: A0A2Y9GGJ6
names: Subcellular Location Annotation
messages: Nucleus

29088:THOC2
gene id: 29088:THOC2
uniprot id: A0A2Y9GSV7
uniprot id: A0A8M1M9V6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THOC2 family.
messages: Component of the THO complex, which is composed of THOC1, THOC2, THOC3, THOC5, THOC6 and THOC7; together with at least ALYREF/THOC4, DDX39B, SARNP/CIP29 and CHTOP, THO forms the transcription/export (TREX) complex which seems to have a dynamic structure involving ATP-dependent remodeling. Interacts with THOC1, POLDIP3 and ZC3H11A.
messages: Nucleus

29088:GLUL
gene id: 29088:GLUL
uniprot id: A0A2Y9GH54
uniprot id: A0A2Y9GM27
uniprot id: A0A8M1MGZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cell membrane
messages: Membrane
messages: Microsome

29088:GSDMB
gene id: 29088:GSDMB
uniprot id: A0A2Y9IF75
names: Similarity
messages: Belongs to the gasdermin family.

29088:TMPRSS5
gene id: 29088:TMPRSS5
uniprot id: A0A8M1MXX8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110571646
gene id: 29088:LOC110571646
uniprot id: A0A2Y9G8Y1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

29088:PTGDR
gene id: 29088:PTGDR
uniprot id: A0A2Y9HZP6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:DPYSL4
gene id: 29088:DPYSL4
uniprot id: A0A2Y9IAZ7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

29088:ITGA9
gene id: 29088:ITGA9
uniprot id: A0A2Y9G633
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

29088:SUSD6
gene id: 29088:SUSD6
uniprot id: A0A2Y9G8S3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:SGCZ
gene id: 29088:SGCZ
uniprot id: A0A2Y9HDQ4
uniprot id: A0A2Y9HJX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

29088:OTUD7B
gene id: 29088:OTUD7B
uniprot id: A0A2Y9GWY6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:ELAPOR1
gene id: 29088:ELAPOR1
uniprot id: A0A2Y9H288
uniprot id: A0A8M1M828
uniprot id: A0A8M1M8B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

29088:SLC27A6
gene id: 29088:SLC27A6
uniprot id: A0A2Y9I1D5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

29088:XKR5
gene id: 29088:XKR5
uniprot id: A0A2Y9HK36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

29088:ATP7B
gene id: 29088:ATP7B
uniprot id: A0A2Y9G539
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

29088:LOC110590844
gene id: 29088:LOC110590844
uniprot id: A0A8M1M493
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

29088:AKAP4
gene id: 29088:AKAP4
uniprot id: A0A2Y9G5V6
names: Similarity
messages: Belongs to the AKAP110 family.

29088:LOC110571455
gene id: 29088:LOC110571455
uniprot id: A0A8M1MLT0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

29088:GAL3ST2
gene id: 29088:GAL3ST2
uniprot id: A0A2Y9G6Q2
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

29088:DLST
gene id: 29088:DLST
uniprot id: A0A2Y9G893
uniprot id: A0A2Y9G8D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

29088:LOC110570674
gene id: 29088:LOC110570674
uniprot id: A0A2Y9G5U1
uniprot id: A0A8M1MUV1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

29088:FAM135B
gene id: 29088:FAM135B
uniprot id: A0A2Y9H2C6
names: Similarity
messages: Belongs to the FAM135 family.

29088:MYCL
gene id: 29088:MYCL
uniprot id: A0A2Y9GPX0
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

29088:LOC110591359
gene id: 29088:LOC110591359
uniprot id: A0A2Y9I246
names: Subcellular Location Annotation
messages: Membrane

29088:TCEA3
gene id: 29088:TCEA3
uniprot id: A0A2Y9GMS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

29088:RPRD1B
gene id: 29088:RPRD1B
uniprot id: A0A2Y9GZD6
uniprot id: A0A2Y9H3Z7
uniprot id: A0A8M1ML48
names: Function
names: Similarity
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD.

29088:TLCD5
gene id: 29088:TLCD5
uniprot id: A0A2Y9HR54
names: Subcellular Location Annotation
messages: Membrane

29088:VIL1
gene id: 29088:VIL1
uniprot id: A0A2Y9I9Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: filopodium tip
messages: lamellipodium
messages: microvillus
messages: ruffle

29088:LOC110590462
gene id: 29088:LOC110590462
uniprot id: A0A8M1MLV2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

29088:ALLC
gene id: 29088:ALLC
uniprot id: A0A2Y9HVE9
names: Function
names: Similarity
messages: Belongs to the allantoicase family.
messages: The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals.

29088:DNAAF4
gene id: 29088:DNAAF4
uniprot id: A0A2Y9HD46
names: Subcellular Location Annotation
messages: Dynein axonemal particle
messages: neuron projection

29088:LOC110587191
gene id: 29088:LOC110587191
uniprot id: A0A2Y9HUR8
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.
messages: Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.

29088:RPS18
gene id: 29088:RPS18
uniprot id: A0A2Y9GSF5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.

29088:LOC110590306
gene id: 29088:LOC110590306
uniprot id: A0A2Y9I3G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

29088:IL7
gene id: 29088:IL7
uniprot id: A0A2Y9GY68
uniprot id: A0A2Y9H2R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-7/IL-9 family.
messages: Hematopoietic cytokine that plays an essential role in the development, expansion, and survival of naive and memory T-cells and B-cells thereby regulating the number of mature lymphocytes and maintaining lymphoid homeostasis.
messages: Secreted

29088:ACADL
gene id: 29088:ACADL
uniprot id: A0A2Y9I494
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Homotetramer.
messages: Mitochondrion matrix

29088:NAA38
gene id: 29088:NAA38
uniprot id: A0A2Y9HFC0
names: Function
names: Similarity
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.

29088:LOC123324565
gene id: 29088:LOC123324565
uniprot id: A0A8M1M8E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornifin (SPRR) family.
messages: Cytoplasm

29088:EIF6
gene id: 29088:EIF6
uniprot id: A0A8M1MQ53
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)-dependent protein kinase C activity. In tissues responsive to insulin, controls fatty acid synthesis and glycolysis by exerting translational control of adipogenic transcription factors such as CEBPB, CEBPD and ATF4 that have G/C rich or uORF in their 5'UTR. Required for ROS-dependent megakaryocyte maturation and platelets formation, controls the expression of mitochondrial respiratory chain genes involved in reactive oxygen species (ROS) synthesis. Involved in miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Modulates cell cycle progression and global translation of pre-B cells, its activation seems to be rate-limiting in tumorigenesis and tumor growth.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit. Interacts with RACK1. Interacts with DICER1, AGO2, TARBP2, MOV10 and RPL7A; they form a large RNA-induced silencing complex (RISC).
messages: Phosphorylation at Ser-174 and Ser-175 promotes nuclear export.
messages: nucleolus

29088:CPNE3
gene id: 29088:CPNE3
uniprot id: A0A2Y9H1H3
names: Similarity
messages: Belongs to the copine family.

29088:LOC110578248
gene id: 29088:LOC110578248
uniprot id: A0A2Y9H072
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

29088:GRIN1
gene id: 29088:GRIN1
uniprot id: A0A8M1MRA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

29088:TRPV4
gene id: 29088:TRPV4
uniprot id: A0A2Y9I5D4
uniprot id: A0A2Y9ICQ9
names: Subcellular Location Annotation
messages: Membrane

29088:PDCD5
gene id: 29088:PDCD5
uniprot id: A0A2Y9I4F0
uniprot id: A0A8M1MW77
names: Similarity
messages: Belongs to the PDCD5 family.

29088:LOC110593819
gene id: 29088:LOC110593819
uniprot id: A0A2Y9IAY5
names: Similarity
messages: Belongs to the peptidase S14 family.

29088:CPLANE2
gene id: 29088:CPLANE2
uniprot id: A0A2Y9GMM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells.
messages: cilium basal body

29088:PHAX
gene id: 29088:PHAX
uniprot id: A0A2Y9I1A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PHAX family.
messages: Cytoplasm

29088:SLITRK3
gene id: 29088:SLITRK3
uniprot id: A0A2Y9I7V5
names: Similarity
messages: Belongs to the SLITRK family.

29088:AVL9
gene id: 29088:AVL9
uniprot id: A0A2Y9H7T6
names: Subcellular Location Annotation
messages: Endosome
messages: Recycling endosome

29088:CEP57
gene id: 29088:CEP57
uniprot id: A0A2Y9G6X5
uniprot id: A0A8M1MPA6
uniprot id: A0A8M1MR75
uniprot id: A0A8M1MXV8
names: Similarity
messages: Belongs to the translokin family.

29088:WNT2
gene id: 29088:WNT2
uniprot id: A0A2Y9I0E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

29088:TMED10
gene id: 29088:TMED10
uniprot id: A0A2Y9G8X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:CAPZA2
gene id: 29088:CAPZA2
uniprot id: A0A2Y9HTS4
uniprot id: A0A2Y9I060
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

29088:LOC110571700
gene id: 29088:LOC110571700
uniprot id: A0A2Y9GCZ3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

29088:GUCY1B1
gene id: 29088:GUCY1B1
uniprot id: A0A8M1M691
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

29088:BOLA1
gene id: 29088:BOLA1
uniprot id: A0A2Y9H130
names: Similarity
messages: Belongs to the BolA/IbaG family.

29088:BAZ1B
gene id: 29088:BAZ1B
uniprot id: A0A2Y9HWQ3
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110577715
gene id: 29088:LOC110577715
uniprot id: A0A8M1M241
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

29088:PRDX1
gene id: 29088:PRDX1
uniprot id: A0A2Y9GNP6
uniprot id: A0A8M1MAA4
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

29088:HADHA
gene id: 29088:HADHA
uniprot id: A0A2Y9HND8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

29088:LOC110570414
gene id: 29088:LOC110570414
uniprot id: A0A8M1MZ03
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

29088:SYNJ2
gene id: 29088:SYNJ2
uniprot id: A0A8M1MHH2
uniprot id: A0A8M1MHH9
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

29088:NLRP5
gene id: 29088:NLRP5
uniprot id: A0A2Y9GFV0
names: Similarity
messages: Belongs to the NLRP family.

29088:DOCK2
gene id: 29088:DOCK2
uniprot id: A0A2Y9HQC4
names: Similarity
messages: Belongs to the DOCK family.

29088:LOC110592169
gene id: 29088:LOC110592169
uniprot id: A0A8M1M8G1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

29088:HMGN4
gene id: 29088:HMGN4
uniprot id: A0A2Y9HLF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

29088:FAM25A
gene id: 29088:FAM25A
uniprot id: A0A2Y9HVU0
names: Similarity
messages: Belongs to the FAM25 family.

29088:RBP2
gene id: 29088:RBP2
uniprot id: A0A2Y9G9H8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:RPS15
gene id: 29088:RPS15
uniprot id: A0A2Y9G517
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

29088:LOC110576502
gene id: 29088:LOC110576502
uniprot id: A0A2Y9GU24
names: Subcellular Location Annotation
messages: Membrane

29088:FGF9
gene id: 29088:FGF9
uniprot id: A0A2Y9G4E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heparin-binding growth factors family.
messages: Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.
messages: Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.
messages: Secreted

29088:NR4A3
gene id: 29088:NR4A3
uniprot id: A0A2Y9H687
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

29088:SLC30A6
gene id: 29088:SLC30A6
uniprot id: A0A2Y9HTF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

29088:FCHO2
gene id: 29088:FCHO2
uniprot id: A0A2Y9I885
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FCHO family.
messages: clathrin-coated pit

29088:ZIC4
gene id: 29088:ZIC4
uniprot id: A0A2Y9GR23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

29088:CAMK1
gene id: 29088:CAMK1
uniprot id: A0A2Y9HG10
uniprot id: A0A8M1MF05
names: Similarity
messages: Belongs to the protein kinase superfamily.

29088:ALG8
gene id: 29088:ALG8
uniprot id: A0A2Y9I8R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:RPS14
gene id: 29088:RPS14
uniprot id: A0A2Y9HM51
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

29088:SUSD1
gene id: 29088:SUSD1
uniprot id: A0A2Y9H6I4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:LOC110592157
gene id: 29088:LOC110592157
uniprot id: A0A8M1M874
names: Similarity
messages: Belongs to the PDCD5 family.

29088:F11R
gene id: 29088:F11R
uniprot id: A0A2Y9GJV4
uniprot id: A0A8M1MD90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily.
messages: Cell membrane
messages: Membrane
messages: tight junction

29088:PTPRT
gene id: 29088:PTPRT
uniprot id: A0A8M1MWJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

29088:IL6
gene id: 29088:IL6
uniprot id: A0A2Y9H184
uniprot id: A0A2Y9H1C7
uniprot id: A0A2Y9H1E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Component of a hexamer of two molecules each of IL6, IL6R and IL6ST; first binds to IL6R to associate with the signaling subunit IL6ST. Interacts with IL6R (via the N-terminal ectodomain); this interaction may be affected by IL6R-binding with SORL1, hence decreasing IL6 cis signaling. Interacts with SORL1 (via the N-terminal ectodomain); this interaction leads to IL6 internalization and lysosomal degradation. May form a trimeric complex with the soluble SORL1 ectodomain and soluble IL6R receptor; this interaction might stabilize circulating IL6, hence promoting IL6 trans signaling.
messages: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.
messages: IL6 is a potent inducer of the acute phase response. Rapid production of IL6 contributes to host defense during infection and tissue injury, but excessive IL6 synthesis is involved in disease pathology. In the innate immune response, is synthesized by myeloid cells, such as macrophages and dendritic cells, upon recognition of pathogens through toll-like receptors (TLRs) at the site of infection or tissue injury (By similarity). In the adaptive immune response, is required for the differentiation of B cells into immunoglobulin-secreting cells. Plays a major role in the differentiation of CD4(+) T cell subsets. Essential factor for the development of T follicular helper (Tfh) cells that are required for the induction of germinal-center formation. Required to drive naive CD4(+) T cells to the Th17 lineage. Also required for proliferation of myeloma cells and the survival of plasmablast cells.
messages: Secreted

29088:TARS1
gene id: 29088:TARS1
uniprot id: A0A2Y9HJ73
uniprot id: A0A8M1MGE4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

29088:CKM
gene id: 29088:CKM
uniprot id: A0A2Y9GHN4
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

29088:CITED4
gene id: 29088:CITED4
uniprot id: A0A2Y9GK21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

29088:HOXC6
gene id: 29088:HOXC6
uniprot id: A0A2Y9GT28
uniprot id: A0A8M1MDW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

29088:SLC22A7
gene id: 29088:SLC22A7
uniprot id: A0A2Y9H7U5
uniprot id: A0A2Y9H7V6
names: Subcellular Location Annotation
messages: Membrane

29088:ARHGDIB
gene id: 29088:ARHGDIB
uniprot id: A0A2Y9H8U7
names: Similarity
messages: Belongs to the Rho GDI family.

29088:ATIC
gene id: 29088:ATIC
uniprot id: A0A2Y9I4T7
uniprot id: A0A2Y9I4Z2
uniprot id: A0A2Y9I9N7
uniprot id: A0A8M1M634
uniprot id: A0A8M1M6D7
names: Similarity
messages: Belongs to the PurH family.

29088:LIX1L
gene id: 29088:LIX1L
uniprot id: A0A2Y9H140
names: Similarity
messages: Belongs to the LIX1 family.

29088:KCNH3
gene id: 29088:KCNH3
uniprot id: A0A2Y9IDY1
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

29088:ANAPC16
gene id: 29088:ANAPC16
uniprot id: A0A2Y9HU78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

29088:RC3H2
gene id: 29088:RC3H2
uniprot id: A0A2Y9HAT9
names: Subcellular Location Annotation
messages: P-body

29088:FGF13
gene id: 29088:FGF13
uniprot id: A0A8M1M0Y4
uniprot id: A0A8M1M3H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: dendrite
messages: filopodium
messages: growth cone
messages: sarcolemma

29088:ROMO1
gene id: 29088:ROMO1
uniprot id: A0A2Y9H643
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

29088:LOC110589621
gene id: 29088:LOC110589621
uniprot id: A0A2Y9HVP9
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:EIF3G
gene id: 29088:EIF3G
uniprot id: A0A2Y9IEZ3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of FRAP1 and RAPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts (via C-terminus) with AIFM1 (via N-terminus).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. This subunit can bind 18S rRNA.
messages: perinuclear region

29088:SLC4A10
gene id: 29088:SLC4A10
uniprot id: A0A8M1M5V0
uniprot id: A0A8M1M651
uniprot id: A0A8M1M9Q0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:PCCA
gene id: 29088:PCCA
uniprot id: A0A2Y9HJ90
uniprot id: A0A2Y9HQJ4
uniprot id: A0A8M1M6G2
uniprot id: A0A8M1M6R0
uniprot id: A0A8M1M8W3
uniprot id: A0A8M1MAA2
uniprot id: A0A8M1MEN5
names: Subcellular Location Annotation
messages: Mitochondrion matrix

29088:C7
gene id: 29088:C7
uniprot id: A0A2Y9HK94
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:MUS81
gene id: 29088:MUS81
uniprot id: A0A2Y9GU06
uniprot id: A0A8M1MQB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

29088:DDX55
gene id: 29088:DDX55
uniprot id: A0A2Y9HW93
uniprot id: A0A2Y9HXU4
names: Similarity
messages: Belongs to the DEAD box helicase family.

29088:ARRDC3
gene id: 29088:ARRDC3
uniprot id: A0A2Y9HYS3
names: Similarity
messages: Belongs to the arrestin family.

29088:LOC110590435
gene id: 29088:LOC110590435
uniprot id: A0A2Y9HZA7
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

29088:LOC110592158
gene id: 29088:LOC110592158
uniprot id: A0A8M1M9W2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: Component of the 40S ribosomal subunit.

29088:LOC110577181
gene id: 29088:LOC110577181
uniprot id: A0A2Y9GW74
uniprot id: A0A8M1MUC1
names: Similarity
messages: Belongs to the cytochrome b5 family.

29088:TAF9
gene id: 29088:TAF9
uniprot id: A0A2Y9I1N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

29088:CDH1
gene id: 29088:CDH1
uniprot id: A0A2Y9IG40
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
messages: Membrane
messages: trans-Golgi network

29088:LOC110590128
gene id: 29088:LOC110590128
uniprot id: A0A2Y9I4Q3
names: Subcellular Location Annotation
messages: Membrane

29088:ZFYVE28
gene id: 29088:ZFYVE28
uniprot id: A0A8M1M5A7
names: Similarity
messages: Belongs to the lst-2 family.

29088:CYRIB
gene id: 29088:CYRIB
uniprot id: A0A2Y9GXU0
uniprot id: A0A2Y9GY52
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CYRI family.
messages: Interacts with RAC1 (GTP-bound form preferentially).
messages: Membrane

29088:HSPG2
gene id: 29088:HSPG2
uniprot id: A0A8M1MB41
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

29088:POLR3GL
gene id: 29088:POLR3GL
uniprot id: A0A2Y9GX22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

29088:SLC25A15
gene id: 29088:SLC25A15
uniprot id: A0A2Y9G891
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:LOC110571152
gene id: 29088:LOC110571152
uniprot id: A0A8M1M9S0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

29088:ATF7IP2
gene id: 29088:ATF7IP2
uniprot id: A0A8M1MBF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

29088:LOC110577356
gene id: 29088:LOC110577356
uniprot id: A0A8M1MHA8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:PSMG2
gene id: 29088:PSMG2
uniprot id: A0A2Y9GHS8
uniprot id: A0A2Y9GHW3
uniprot id: A0A8M1MVP0
uniprot id: A0A8M1MYQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

29088:ARHGEF3
gene id: 29088:ARHGEF3
uniprot id: A0A2Y9HGD4
uniprot id: A0A8M1MZ13
uniprot id: A0A8M1MZ14
names: Function
names: Subcellular Location Annotation
messages: Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
messages: Cytoplasm

29088:LOC110570045
gene id: 29088:LOC110570045
uniprot id: A0A2Y9G6A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

29088:SNX3
gene id: 29088:SNX3
uniprot id: A0A2Y9HAZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome
messages: Endosome
messages: phagosome

29088:IER2
gene id: 29088:IER2
uniprot id: A0A2Y9IHL6
names: Similarity
messages: Belongs to the IER family.

29088:ARAP3
gene id: 29088:ARAP3
uniprot id: A0A2Y9I0X1
names: Subcellular Location Annotation
messages: Cytoplasm

29088:C13H9orf64
gene id: 29088:C13H9orf64
uniprot id: A0A2Y9G606
names: Function
names: Similarity
messages: Belongs to the queuosine salvage protein family.
messages: Involved in salvaging queuosine.

29088:PMVK
gene id: 29088:PMVK
uniprot id: A0A2Y9GF31
names: Subcellular Location Annotation
messages: cytosol

29088:LOC110578640
gene id: 29088:LOC110578640
uniprot id: A0A8M1MS83
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

29088:ATP6V0C
gene id: 29088:ATP6V0C
uniprot id: A0A2Y9HQH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

29088:MTCH2
gene id: 29088:MTCH2
uniprot id: A0A2Y9GPA0
uniprot id: A0A2Y9GTD8
uniprot id: A0A2Y9GV28
uniprot id: A0A8M1MSX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:MEN1
gene id: 29088:MEN1
uniprot id: A0A2Y9GPW1
uniprot id: A0A2Y9GVC2
names: Subcellular Location Annotation
messages: Nucleus

29088:DHX58
gene id: 29088:DHX58
uniprot id: A0A2Y9GIR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

29088:SLC26A9
gene id: 29088:SLC26A9
uniprot id: A0A2Y9GYE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport.
messages: Membrane

29088:RANBP17
gene id: 29088:RANBP17
uniprot id: A0A2Y9HVL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

29088:STOML1
gene id: 29088:STOML1
uniprot id: A0A2Y9HCY1
uniprot id: A0A2Y9HD26
uniprot id: A0A2Y9HDA9
uniprot id: A0A2Y9HJK8
uniprot id: A0A8M1MMU4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

29088:TIMELESS
gene id: 29088:TIMELESS
uniprot id: A0A2Y9GUL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the timeless family.
messages: Nucleus

29088:TMEM9
gene id: 29088:TMEM9
uniprot id: A0A2Y9GGA5
names: Similarity
messages: Belongs to the TMEM9 family.

29088:LOC110576133
gene id: 29088:LOC110576133
uniprot id: A0A2Y9GSR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Endoplasmic reticulum membrane

29088:DTNA
gene id: 29088:DTNA
uniprot id: A0A2Y9GRQ1
uniprot id: A0A2Y9GRQ6
uniprot id: A0A2Y9GRR1
uniprot id: A0A2Y9GRV3
uniprot id: A0A2Y9GRV8
uniprot id: A0A2Y9GRY8
uniprot id: A0A2Y9GVU2
uniprot id: A0A2Y9GXF7
uniprot id: A0A2Y9GXG1
uniprot id: A0A8M1MT43
uniprot id: A0A8M1MT47
uniprot id: A0A8M1MT53
uniprot id: A0A8M1MUY8
uniprot id: A0A8M1MWB4
uniprot id: A0A8M1MYV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dystrophin family. Dystrobrevin subfamily.
messages: Cytoplasm

29088:C4H8orf33
gene id: 29088:C4H8orf33
uniprot id: A0A2Y9GYE4
uniprot id: A0A2Y9H4P3
names: Similarity
messages: Belongs to the UPF0488 family.

29088:LOC110586743
gene id: 29088:LOC110586743
uniprot id: A0A8M1MHV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

29088:AP3M2
gene id: 29088:AP3M2
uniprot id: A0A2Y9GDW7
uniprot id: A0A8M1M5D0
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

29088:TRMT112
gene id: 29088:TRMT112
uniprot id: A0A2Y9GPQ0
uniprot id: A0A8M1MPM0
names: Similarity
messages: Belongs to the TRM112 family.

29088:LOC110578045
gene id: 29088:LOC110578045
uniprot id: A0A8M1M9W5
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

29088:CDK7
gene id: 29088:CDK7
uniprot id: A0A2Y9I1L2
uniprot id: A0A2Y9I1X2
uniprot id: A0A2Y9I243
uniprot id: A0A2Y9I8M3
uniprot id: A0A8M1MPY6
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

29088:ITFG1
gene id: 29088:ITFG1
uniprot id: A0A2Y9IC49
names: Similarity
messages: Belongs to the TIP family.

29088:ACAD8
gene id: 29088:ACAD8
uniprot id: A0A2Y9HJE8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

29088:NDC80
gene id: 29088:NDC80
uniprot id: A0A2Y9GVL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

29088:KPNA2
gene id: 29088:KPNA2
uniprot id: A0A2Y9G4Z0
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

29088:KCNK12
gene id: 29088:KCNK12
uniprot id: A0A2Y9HZ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

29088:MGST2
gene id: 29088:MGST2
uniprot id: A0A2Y9G7P8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

29088:ATP5F1B
gene id: 29088:ATP5F1B
uniprot id: A0A2Y9GYI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

29088:NDST1
gene id: 29088:NDST1
uniprot id: A0A2Y9HY19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

29088:EIF1AX
gene id: 29088:EIF1AX
uniprot id: A0A2Y9GFI5
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

29088:RPL23
gene id: 29088:RPL23
uniprot id: A0A2Y9I882
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Component of the large ribosomal subunit.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

29088:BTBD10
gene id: 29088:BTBD10
uniprot id: A0A2Y9GW20
uniprot id: A0A8M1MN09
names: Subcellular Location Annotation
messages: Cytoplasm

29088:MMP28
gene id: 29088:MMP28
uniprot id: A0A2Y9I7Q9
uniprot id: A0A2Y9IC66
names: Similarity
messages: Belongs to the peptidase M10A family.

29088:GRM6
gene id: 29088:GRM6
uniprot id: A0A2Y9HA34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

29088:LOC110591290
gene id: 29088:LOC110591290
uniprot id: A0A2Y9HWD6
names: Similarity
messages: Belongs to the NAC-beta family.

29088:AQP8
gene id: 29088:AQP8
uniprot id: A0A2Y9I3W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

29088:PHLDB1
gene id: 29088:PHLDB1
uniprot id: A0A8M1MRB3
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

29088:F12
gene id: 29088:F12
uniprot id: A0A2Y9HSB4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

29088:SLC7A1
gene id: 29088:SLC7A1
uniprot id: A0A2Y9G712
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

29088:FXYD5
gene id: 29088:FXYD5
uniprot id: A0A2Y9HYB9
uniprot id: A0A2Y9I4S8
names: Similarity
messages: Belongs to the FXYD family.

29088:VPS11
gene id: 29088:VPS11
uniprot id: A0A2Y9HJZ8
uniprot id: A0A8M1MMR9
uniprot id: A0A8M1MPQ7
uniprot id: A0A8M1MR31
uniprot id: A0A8M1MWX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS11 family.
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: autophagosome
messages: clathrin-coated vesicle

29088:LOC110573271
gene id: 29088:LOC110573271
uniprot id: A0A2Y9GIW2
uniprot id: A0A8M1MZ29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.
messages: centrosome

29088:PRDM12
gene id: 29088:PRDM12
uniprot id: A0A2Y9H6E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Involved in the positive regulation of histone H3-K9 dimethylation.
messages: Nucleus

29088:GDPD4
gene id: 29088:GDPD4
uniprot id: A0A8M1MPD1
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

29088:SLC25A51
gene id: 29088:SLC25A51
uniprot id: A0A2Y9HD43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:NF2
gene id: 29088:NF2
uniprot id: A0A2Y9IAI5
uniprot id: A0A2Y9ID28
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton
messages: microvillus

29088:IFT20
gene id: 29088:IFT20
uniprot id: A0A2Y9I8S4
uniprot id: A0A8M1MWQ3
uniprot id: A0A8M1MXI8
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cis-Golgi network

29088:LOC110578633
gene id: 29088:LOC110578633
uniprot id: A0A2Y9H1B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

29088:TMEM184A
gene id: 29088:TMEM184A
uniprot id: A0A2Y9GA42
names: Subcellular Location Annotation
messages: Membrane

29088:SEPTIN7
gene id: 29088:SEPTIN7
uniprot id: A0A2Y9HTN9
uniprot id: A0A2Y9HU76
uniprot id: A0A2Y9HU77
uniprot id: A0A2Y9HZ31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Filament-forming cytoskeletal GTPase.
messages: Midbody
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: cilium axoneme
messages: flagellum
messages: kinetochore
messages: spindle

29088:ALAS2
gene id: 29088:ALAS2
uniprot id: A0A8M1M3I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

29088:RNASE9
gene id: 29088:RNASE9
uniprot id: A0A2Y9HHV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Does not exhibit any ribonuclease activity.
messages: Secreted

29088:PFKM
gene id: 29088:PFKM
uniprot id: A0A2Y9I936
uniprot id: A0A2Y9IDK5
uniprot id: A0A8M1MBZ3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:GUCY1A2
gene id: 29088:GUCY1A2
uniprot id: A0A2Y9HKS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

29088:TBL1XR1
gene id: 29088:TBL1XR1
uniprot id: A0A2Y9H8L3
names: Similarity
messages: Belongs to the WD repeat EBI family.

29088:FASN
gene id: 29088:FASN
uniprot id: A0A2Y9GC56
names: Function
messages: Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.

29088:ECHDC1
gene id: 29088:ECHDC1
uniprot id: A0A2Y9HCA7
uniprot id: A0A2Y9HIT1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

29088:NAXE
gene id: 29088:NAXE
uniprot id: A0A2Y9GI42
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis.
messages: Homodimer. Interacts with APOA1 and APOA2.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Secreted
messages: Undergoes physiological phosphorylation during sperm capacitation, downstream to PKA activation.

29088:RAB3GAP1
gene id: 29088:RAB3GAP1
uniprot id: A0A2Y9HII3
uniprot id: A0A2Y9HPS2
uniprot id: A0A8M1M938
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP catalytic subunit family.
messages: Cytoplasm

29088:NDUFS6
gene id: 29088:NDUFS6
uniprot id: A0A2Y9GYA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS6 subunit family.
messages: Mitochondrion inner membrane

29088:LOC110581858
gene id: 29088:LOC110581858
uniprot id: A0A2Y9H740
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

29088:UNC45A
gene id: 29088:UNC45A
uniprot id: A0A2Y9GB30
uniprot id: A0A2Y9GDV0
names: Subcellular Location Annotation
messages: perinuclear region

29088:SH3PXD2B
gene id: 29088:SH3PXD2B
uniprot id: A0A2Y9I5S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm
messages: podosome

29088:TRHDE
gene id: 29088:TRHDE
uniprot id: A0A2Y9G5E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Membrane

29088:GPR4
gene id: 29088:GPR4
uniprot id: A0A2Y9GCP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

29088:ATXN2
gene id: 29088:ATXN2
uniprot id: A0A2Y9HY91
uniprot id: A0A8M1MV33
uniprot id: A0A8M1MWF4
uniprot id: A0A8M1MYW2
names: Similarity
messages: Belongs to the ataxin-2 family.

29088:XYLT1
gene id: 29088:XYLT1
uniprot id: A0A2Y9HQ33
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

29088:ADAM30
gene id: 29088:ADAM30
uniprot id: A0A2Y9H2X5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:KIF2A
gene id: 29088:KIF2A
uniprot id: A0A2Y9I645
uniprot id: A0A8M1MFZ0
uniprot id: A0A8M1MFZ7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:XKR4
gene id: 29088:XKR4
uniprot id: A0A2Y9GXH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

29088:IL1RAPL2
gene id: 29088:IL1RAPL2
uniprot id: A0A2Y9G4U6
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

29088:TBX5
gene id: 29088:TBX5
uniprot id: A0A2Y9HRV0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

29088:ADORA3
gene id: 29088:ADORA3
uniprot id: A0A2Y9H2I7
uniprot id: A0A2Y9H2M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

29088:KIF26B
gene id: 29088:KIF26B
uniprot id: A0A2Y9H1V1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

29088:LOC110589166
gene id: 29088:LOC110589166
uniprot id: A0A2Y9HUQ4
uniprot id: A0A2Y9HUR0
uniprot id: A0A8M1MDX8
names: Subcellular Location Annotation
messages: Cell junction
messages: Golgi stack
messages: Synapse
messages: cytoskeleton

29088:LOC110581189
gene id: 29088:LOC110581189
uniprot id: A0A2Y9H4R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ESCO1
gene id: 29088:ESCO1
uniprot id: A0A2Y9GV36
names: Subcellular Location Annotation
messages: Nucleus

29088:AGL
gene id: 29088:AGL
uniprot id: A0A2Y9H7T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

29088:SPATA18
gene id: 29088:SPATA18
uniprot id: A0A2Y9I529
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIEAP family.
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion outer membrane

29088:MAP7D3
gene id: 29088:MAP7D3
uniprot id: A0A8M1M1V3
names: Similarity
messages: Belongs to the MAP7 family.

29088:FGF22
gene id: 29088:FGF22
uniprot id: A0A2Y9IFA2
uniprot id: A0A2Y9II99
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

29088:MTCL1
gene id: 29088:MTCL1
uniprot id: A0A8M1MSQ0
uniprot id: A0A8M1MUJ1
uniprot id: A0A8M1MVX0
uniprot id: A0A8M1MYS3
names: Similarity
messages: Belongs to the SOGA family.

29088:NPC1L1
gene id: 29088:NPC1L1
uniprot id: A0A2Y9IDC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

29088:STXBP5
gene id: 29088:STXBP5
uniprot id: A0A2Y9HBS1
uniprot id: A0A2Y9HBY7
uniprot id: A0A2Y9HC61
uniprot id: A0A2Y9HHW9
uniprot id: A0A8M1MJZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

29088:LOC110591947
gene id: 29088:LOC110591947
uniprot id: A0A2Y9I405
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

29088:PTPN2
gene id: 29088:PTPN2
uniprot id: A0A2Y9GHQ9
uniprot id: A0A2Y9GHT3
uniprot id: A0A2Y9GHW7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

29088:RPL18
gene id: 29088:RPL18
uniprot id: A0A2Y9GGA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL18 family.
messages: Rough endoplasmic reticulum

29088:DLX4
gene id: 29088:DLX4
uniprot id: A0A2Y9I7X4
uniprot id: A0A8M1MUT4
names: Subcellular Location Annotation
messages: Nucleus

29088:EIF4A3
gene id: 29088:EIF4A3
uniprot id: A0A2Y9GBY0
names: Similarity
messages: Belongs to the DEAD box helicase family.

29088:LOC110580473
gene id: 29088:LOC110580473
uniprot id: A0A2Y9H2P1
names: Similarity
messages: Belongs to the peptidase A1 family.

29088:LOC110591959
gene id: 29088:LOC110591959
uniprot id: A0A2Y9GXD8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

29088:SAE1
gene id: 29088:SAE1
uniprot id: A0A2Y9GCS3
uniprot id: A0A2Y9GCX9
uniprot id: A0A8M1M0X8
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

29088:MPI
gene id: 29088:MPI
uniprot id: A0A2Y9HCN2
uniprot id: A0A2Y9HCZ7
uniprot id: A0A2Y9HIU2
uniprot id: A0A2Y9HJA3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

29088:GHR
gene id: 29088:GHR
uniprot id: A0A2Y9HX90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: On growth hormone (GH) binding, forms homodimers and binds JAK2 via a box 1-containing domain. Binding to SOCS3 inhibits JAK2 activation, binding to CIS and SOCS2 inhibits STAT5 activation.
messages: The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.

29088:NNAT
gene id: 29088:NNAT
uniprot id: A0A2Y9GZG8
uniprot id: A0A2Y9H3X3
uniprot id: A0A8M1ML39
names: Similarity
messages: Belongs to the neuronatin family.

29088:CPSF3
gene id: 29088:CPSF3
uniprot id: A0A2Y9HP00
uniprot id: A0A2Y9HPE3
uniprot id: A0A2Y9HVS9
uniprot id: A0A8M1MP56
names: Subcellular Location Annotation
messages: Nucleus

29088:IFT46
gene id: 29088:IFT46
uniprot id: A0A2Y9HRP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT46 family.
messages: cilium
messages: cilium basal body

29088:LOC110582484
gene id: 29088:LOC110582484
uniprot id: A0A2Y9H986
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:IL4
gene id: 29088:IL4
uniprot id: A0A2Y9I0P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-4/IL-13 family.
messages: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.
messages: Secreted

29088:A2ML1
gene id: 29088:A2ML1
uniprot id: A0A2Y9H8D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

29088:LOC123326012
gene id: 29088:LOC123326012
uniprot id: A0A8M1MLT7
names: Similarity
messages: Belongs to the PPDPF family.

29088:SOX3
gene id: 29088:SOX3
uniprot id: A0A2Y9GLX0
uniprot id: A0A2Y9GM76
names: Subcellular Location Annotation
messages: Nucleus

29088:FAM162B
gene id: 29088:FAM162B
uniprot id: A0A2Y9HHY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

29088:MPDZ
gene id: 29088:MPDZ
uniprot id: A0A2Y9GJC6
names: Subcellular Location Annotation
messages: Cell membrane
messages: tight junction

29088:DCTPP1
gene id: 29088:DCTPP1
uniprot id: A0A2Y9HX47
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homotetramer.
messages: Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.
messages: cytosol

29088:MARS1
gene id: 29088:MARS1
uniprot id: A0A2Y9GUI9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

29088:LOC110585312
gene id: 29088:LOC110585312
uniprot id: A0A2Y9HNK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:BSCL2
gene id: 29088:BSCL2
uniprot id: A0A2Y9GPF7
uniprot id: A0A2Y9GTI4
uniprot id: A0A8M1MN82
uniprot id: A0A8M1MQ62
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:GGH
gene id: 29088:GGH
uniprot id: A0A2Y9GXB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

29088:RPS23
gene id: 29088:RPS23
uniprot id: A0A2Y9HUP9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Component of the 40S small ribosomal subunit.
messages: Rough endoplasmic reticulum

29088:LOC110584442
gene id: 29088:LOC110584442
uniprot id: A0A2Y9HEG3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

29088:LOC110577357
gene id: 29088:LOC110577357
uniprot id: A0A2Y9GSY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

29088:ADCY7
gene id: 29088:ADCY7
uniprot id: A0A2Y9I9P5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

29088:PRPSAP2
gene id: 29088:PRPSAP2
uniprot id: A0A2Y9HES4
uniprot id: A0A8M1MX37
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

29088:CFTR
gene id: 29088:CFTR
uniprot id: A0A2Y9HTW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
messages: Monomer; does not require oligomerization for channel activity. May form oligomers in the membrane (By similarity). Interacts with SLC26A3, SLC26A6 and SLC9A3R1 (By similarity). Interacts with SHANK2 (By similarity). Interacts with MYO6 (By similarity). Interacts (via C-terminus) with GOPC (via PDZ domain); this promotes CFTR internalization and thereby decreases channel activity. Interacts with SLC4A7 through SLC9A3R1. Found in a complex with MYO5B and RAB11A. Interacts with ANO1. Interacts with SLC26A8 (By similarity). Interacts with AHCYL1; the interaction increases CFTR activity (By similarity). Interacts with CSE1L (By similarity). The core-glycosylated form interacts with GORASP2 (via PDZ GRASP-type 1 domain) in respone to ER stress (By similarity). Interacts with MARCHF2; the interaction leads to CFTR ubiqtuitination and degradation.
messages: Recycling endosome membrane

29088:LOC123323399
gene id: 29088:LOC123323399
uniprot id: A0A8M1M9H5
names: Similarity
messages: Belongs to the Gfa family.

29088:FABP3
gene id: 29088:FABP3
uniprot id: A0A2Y9GL01
uniprot id: A0A2Y9GPS6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.

29088:TRAM1
gene id: 29088:TRAM1
uniprot id: A0A2Y9GYK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

29088:DAZL
gene id: 29088:DAZL
uniprot id: A0A2Y9G5T7
names: Subcellular Location Annotation
messages: Cytoplasm

29088:VPS25
gene id: 29088:VPS25
uniprot id: A0A2Y9GEA9
names: Similarity
messages: Belongs to the VPS25 family.

29088:TMOD2
gene id: 29088:TMOD2
uniprot id: A0A2Y9HD63
uniprot id: A0A2Y9HJA1
uniprot id: A0A2Y9HJN6
names: Subcellular Location Annotation
messages: cytoskeleton

29088:KCNA7
gene id: 29088:KCNA7
uniprot id: A0A2Y9GFZ7
names: Subcellular Location Annotation
messages: Membrane

29088:LOC123326189
gene id: 29088:LOC123326189
uniprot id: A0A2Y9HUR8
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.
messages: Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.

29088:MBD4
gene id: 29088:MBD4
uniprot id: A0A2Y9HG38
uniprot id: A0A2Y9HGC4
uniprot id: A0A8M1MEN1
uniprot id: A0A8M1MI13
uniprot id: A0A8M1MNA0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with MLH1.
messages: Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.
messages: Nucleus

29088:HSPA6
gene id: 29088:HSPA6
uniprot id: A0A8M1MMC3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

29088:ADAMTS14
gene id: 29088:ADAMTS14
uniprot id: A0A8M1MIH9
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

29088:SLC24A1
gene id: 29088:SLC24A1
uniprot id: A0A8M1MJQ4
uniprot id: A0A8M1MLR1
uniprot id: A0A8M1MTR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

29088:GALNT12
gene id: 29088:GALNT12
uniprot id: A0A2Y9HBZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:MCRIP2
gene id: 29088:MCRIP2
uniprot id: A0A2Y9HV87
uniprot id: A0A2Y9HWS9
uniprot id: A0A8M1MEH4
uniprot id: A0A8M1MJB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

29088:SLC44A5
gene id: 29088:SLC44A5
uniprot id: A0A2Y9G7S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

29088:LOC110589262
gene id: 29088:LOC110589262
uniprot id: A0A8M1MIN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

29088:CLASP1
gene id: 29088:CLASP1
uniprot id: A0A8M1M6X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLASP family.
messages: centrosome
messages: kinetochore
messages: trans-Golgi network

29088:KCNN2
gene id: 29088:KCNN2
uniprot id: A0A2Y9I1E1
names: Subcellular Location Annotation
messages: Membrane

29088:PPIL2
gene id: 29088:PPIL2
uniprot id: A0A2Y9GWD3
uniprot id: A0A8M1MYW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
messages: Nucleus

29088:AMZ2
gene id: 29088:AMZ2
uniprot id: A0A2Y9G4Z4
uniprot id: A0A2Y9G4Z9
uniprot id: A0A2Y9G5H0
uniprot id: A0A2Y9G7J0
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

29088:TIMM10
gene id: 29088:TIMM10
uniprot id: A0A2Y9GRR8
names: Function
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.

29088:TLE2
gene id: 29088:TLE2
uniprot id: A0A8M1ML12
uniprot id: A0A8M1MPB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

29088:MCUB
gene id: 29088:MCUB
uniprot id: A0A2Y9GM35
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

29088:LOC110594239
gene id: 29088:LOC110594239
uniprot id: A0A2Y9IBU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

29088:RIF1
gene id: 29088:RIF1
uniprot id: A0A8M1MDX9
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

29088:TGM1
gene id: 29088:TGM1
uniprot id: A0A2Y9HHN3
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

29088:SOX11
gene id: 29088:SOX11
uniprot id: A0A2Y9HVP4
names: Subcellular Location Annotation
messages: Nucleus

29088:PRKRA
gene id: 29088:PRKRA
uniprot id: A0A2Y9IBE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRKRA family.
messages: perinuclear region

29088:GALNT3
gene id: 29088:GALNT3
uniprot id: A0A2Y9I994
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:SLC8A2
gene id: 29088:SLC8A2
uniprot id: A0A2Y9GCT4
uniprot id: A0A2Y9GFS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

29088:CENPX
gene id: 29088:CENPX
uniprot id: A0A8M1MZ72
names: Similarity
messages: Belongs to the CENP-X/MHF2 family.

29088:JPT1
gene id: 29088:JPT1
uniprot id: A0A2Y9GCB1
uniprot id: A0A8M1MXM9
uniprot id: A0A8M1MZ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

29088:EPOR
gene id: 29088:EPOR
uniprot id: A0A2Y9IA49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Forms homodimers on EPO stimulation.
messages: Membrane
messages: Receptor for erythropoietin.

29088:SELENOS
gene id: 29088:SELENOS
uniprot id: A0A2Y9GF59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein S family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
messages: Membrane

29088:FAM168A
gene id: 29088:FAM168A
uniprot id: A0A8M1MWS8
names: Similarity
messages: Belongs to the FAM168 family.

29088:GMFG
gene id: 29088:GMFG
uniprot id: A0A2Y9HYF0
uniprot id: A0A2Y9HYN1
uniprot id: A0A2Y9I391
uniprot id: A0A2Y9I531
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

29088:SCTR
gene id: 29088:SCTR
uniprot id: A0A2Y9HPE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

29088:PPP2R3C
gene id: 29088:PPP2R3C
uniprot id: A0A2Y9HGX6
uniprot id: A0A2Y9HN54
uniprot id: A0A8M1MKY0
uniprot id: A0A8M1MSV8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

29088:LOC110594255
gene id: 29088:LOC110594255
uniprot id: A0A8M1M2R3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

29088:RHBDD2
gene id: 29088:RHBDD2
uniprot id: A0A2Y9HX97
names: Subcellular Location Annotation
messages: Membrane

29088:CBWD1
gene id: 29088:CBWD1
uniprot id: A0A2Y9HKR1
uniprot id: A0A8M1MRZ6
uniprot id: A0A8M1MS06
uniprot id: A0A8M1MS11
uniprot id: A0A8M1MTV8
uniprot id: A0A8M1MV84
uniprot id: A0A8M1MV88
uniprot id: A0A8M1MYM4
uniprot id: A0A8M1MYM5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

29088:CPOX
gene id: 29088:CPOX
uniprot id: A0A2Y9GWD6
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

29088:LOC110575488
gene id: 29088:LOC110575488
uniprot id: A0A8M1M1M0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

29088:MRPS6
gene id: 29088:MRPS6
uniprot id: A0A8M1MNF7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

29088:ADCY2
gene id: 29088:ADCY2
uniprot id: A0A2Y9I2S5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

29088:MBOAT4
gene id: 29088:MBOAT4
uniprot id: A0A2Y9HK30
names: Subcellular Location Annotation
messages: Membrane

29088:CXCL12
gene id: 29088:CXCL12
uniprot id: A0A2Y9HWJ8
uniprot id: A0A2Y9I2W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

29088:RPN2
gene id: 29088:RPN2
uniprot id: A0A8M1MMA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

29088:DRAM1
gene id: 29088:DRAM1
uniprot id: A0A2Y9GZM6
names: Subcellular Location Annotation
messages: Membrane

29088:CDIP1
gene id: 29088:CDIP1
uniprot id: A0A2Y9HVL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane
messages: Membrane

29088:HS2ST1
gene id: 29088:HS2ST1
uniprot id: A0A2Y9H261
uniprot id: A0A2Y9H274
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane

29088:MPHOSPH10
gene id: 29088:MPHOSPH10
uniprot id: A0A2Y9GB00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
messages: nucleolus

29088:VSIG1
gene id: 29088:VSIG1
uniprot id: A0A2Y9G5J7
names: Subcellular Location Annotation
messages: Membrane

29088:IL23A
gene id: 29088:IL23A
uniprot id: A0A2Y9GUJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

29088:STIM2
gene id: 29088:STIM2
uniprot id: A0A2Y9G878
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:CTSZ
gene id: 29088:CTSZ
uniprot id: A0A8M1MKY6
uniprot id: A0A8M1MMY5
names: Similarity
messages: Belongs to the peptidase C1 family.

29088:CRKL
gene id: 29088:CRKL
uniprot id: A0A2Y9GWH3
uniprot id: A0A8M1MSM6
names: Similarity
messages: Belongs to the CRK family.

29088:S100A10
gene id: 29088:S100A10
uniprot id: A0A2Y9GWH5
uniprot id: A0A2Y9GWS2
uniprot id: A0A2Y9H0V9
names: Function
messages: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.

29088:SERF1A
gene id: 29088:SERF1A
uniprot id: A0A2Y9HWV5
names: Similarity
messages: Belongs to the SERF family.

29088:SLC37A1
gene id: 29088:SLC37A1
uniprot id: A0A2Y9GAM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.
messages: Membrane

29088:EIF3H
gene id: 29088:EIF3H
uniprot id: A0A2Y9H214
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with RNF139; the interaction leads to protein translation inhibitions in a ubiquitination-dependent manner.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm

29088:HOXB4
gene id: 29088:HOXB4
uniprot id: A0A2Y9I729
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

29088:EMC6
gene id: 29088:EMC6
uniprot id: A0A2Y9I7R2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC6 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:LOC110586754
gene id: 29088:LOC110586754
uniprot id: A0A2Y9HTP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

29088:HBQ1
gene id: 29088:HBQ1
uniprot id: A0A2Y9HWZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the globin family.
messages: Heterotetramer of two alpha chains and two beta chains.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.

29088:LGR5
gene id: 29088:LGR5
uniprot id: A0A2Y9G5F5
uniprot id: A0A8M1MA75
uniprot id: A0A8M1MDQ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:ST13
gene id: 29088:ST13
uniprot id: A0A2Y9H022
uniprot id: A0A8M1MCY6
names: Similarity
messages: Belongs to the FAM10 family.

29088:ISCA2
gene id: 29088:ISCA2
uniprot id: A0A2Y9G861
uniprot id: A0A2Y9GAU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

29088:TMEM178B
gene id: 29088:TMEM178B
uniprot id: A0A2Y9HGY8
names: Similarity
messages: Belongs to the TMEM178 family.

29088:SMO
gene id: 29088:SMO
uniprot id: A0A2Y9HYQ2
uniprot id: A0A2Y9I091
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

29088:LOC123324577
gene id: 29088:LOC123324577
uniprot id: A0A2Y9GPY7
names: Subcellular Location Annotation
messages: Nucleus

29088:CD28
gene id: 29088:CD28
uniprot id: A0A2Y9I528
names: Subcellular Location Annotation
messages: Membrane

29088:GADD45GIP1
gene id: 29088:GADD45GIP1
uniprot id: A0A2Y9IF47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
messages: Belongs to the mitochondrion-specific ribosomal protein mL64 family.
messages: Mitochondrion
messages: Nucleus

29088:DOLK
gene id: 29088:DOLK
uniprot id: A0A2Y9HCD7
names: Similarity
messages: Belongs to the polyprenol kinase family.

29088:GLS2
gene id: 29088:GLS2
uniprot id: A0A2Y9GYQ4
names: Similarity
messages: Belongs to the glutaminase family.

29088:MOXD1
gene id: 29088:MOXD1
uniprot id: A0A2Y9HH42
uniprot id: A0A2Y9HHR9
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

29088:F2
gene id: 29088:F2
uniprot id: A0A2Y9GMM8
names: Caution
names: Function
names: Similarity
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

29088:LOC110572098
gene id: 29088:LOC110572098
uniprot id: A0A8M1M7Y2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

29088:TMPRSS2
gene id: 29088:TMPRSS2
uniprot id: A0A2Y9G764
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:THRA
gene id: 29088:THRA
uniprot id: A0A8M1MZB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

29088:UROS
gene id: 29088:UROS
uniprot id: A0A2Y9I660
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

29088:RTN1
gene id: 29088:RTN1
uniprot id: A0A2Y9HZP8
uniprot id: A0A2Y9I638
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:MS4A3
gene id: 29088:MS4A3
uniprot id: A0A2Y9GNR6
names: Similarity
messages: Belongs to the MS4A family.

29088:SEC24B
gene id: 29088:SEC24B
uniprot id: A0A2Y9GM58
uniprot id: A0A8M1M4Y9
uniprot id: A0A8M1M8K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

29088:HNF1A
gene id: 29088:HNF1A
uniprot id: A0A2Y9I5E7
uniprot id: A0A2Y9I668
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

29088:KRT13
gene id: 29088:KRT13
uniprot id: A0A2Y9GJ32
names: Similarity
messages: Belongs to the intermediate filament family.

29088:LOC110588961
gene id: 29088:LOC110588961
uniprot id: A0A2Y9HTE3
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

29088:LOC110588803
gene id: 29088:LOC110588803
uniprot id: A0A2Y9HTF5
uniprot id: A0A8M1MPX5
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:SLC12A3
gene id: 29088:SLC12A3
uniprot id: A0A2Y9I872
uniprot id: A0A2Y9ICV0
uniprot id: A0A2Y9ICW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

29088:FRAS1
gene id: 29088:FRAS1
uniprot id: A0A8M1M8N4
names: Similarity
messages: Belongs to the FRAS1 family.

29088:LOC110570026
gene id: 29088:LOC110570026
uniprot id: A0A2Y9G3S9
names: Similarity
messages: Belongs to the histone H2B family.

29088:KCNK9
gene id: 29088:KCNK9
uniprot id: A0A2Y9GYK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane
messages: pH-dependent, voltage-insensitive, background potassium channel protein.

29088:SLC17A5
gene id: 29088:SLC17A5
uniprot id: A0A2Y9HGU3
uniprot id: A0A8M1MH92
uniprot id: A0A8M1MH96
uniprot id: A0A8M1MJC0
uniprot id: A0A8M1MJC6
uniprot id: A0A8M1MKN3
uniprot id: A0A8M1MR59
uniprot id: A0A8M1MR65
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110574955
gene id: 29088:LOC110574955
uniprot id: A0A2Y9GQ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVBP family.
messages: Secreted
messages: cytoskeleton

29088:SLC25A43
gene id: 29088:SLC25A43
uniprot id: A0A2Y9GRK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:TRIM3
gene id: 29088:TRIM3
uniprot id: A0A2Y9GVV0
uniprot id: A0A8M1MPG2
uniprot id: A0A8M1MPH3
uniprot id: A0A8M1MRC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

29088:KCNK7
gene id: 29088:KCNK7
uniprot id: A0A2Y9GTZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

29088:KDM3A
gene id: 29088:KDM3A
uniprot id: A0A2Y9HNW7
uniprot id: A0A2Y9HPB8
names: Subcellular Location Annotation
messages: Nucleus

29088:SF3A3
gene id: 29088:SF3A3
uniprot id: A0A2Y9GJP8
uniprot id: A0A8M1MBJ8
names: Similarity
messages: Belongs to the SF3A3 family.

29088:SLC25A10
gene id: 29088:SLC25A10
uniprot id: A0A2Y9GBN7
uniprot id: A0A8M1MWF5
uniprot id: A0A8M1MZ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

29088:LOC123325489
gene id: 29088:LOC123325489
uniprot id: A0A8M1MJ88
names: Subcellular Location Annotation
messages: Nucleus

29088:JUN
gene id: 29088:JUN
uniprot id: A0A2Y9GKE7
uniprot id: A0A2Y9GKL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

29088:MAT2A
gene id: 29088:MAT2A
uniprot id: A0A2Y9HP18
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

29088:UBL3
gene id: 29088:UBL3
uniprot id: A0A2Y9G567
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

29088:ENY2
gene id: 29088:ENY2
uniprot id: A0A2Y9GXJ1
uniprot id: A0A2Y9GXT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3. TREX-2 contains 2 ENY2 chains. The TREX-2 complex interacts with the nucleoporin NUP153. Component of some SAGA transcription coactivator-HAT complexes, at least composed of ATXN7, ATXN7L3, ENY2, GCN5L2, SUPT3H, TAF10, TRRAP and USP22. Within the SAGA complex, ENY2, ATXN7, ATXN7L3, and USP22 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with ATXN7L3, GANP and with the RNA polymerase II. Interacts strongly with ATXN7L3 and ATXN7L3B.
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

29088:PPP1R1C
gene id: 29088:PPP1R1C
uniprot id: A0A8M1MEY3
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

29088:DZIP1
gene id: 29088:DZIP1
uniprot id: A0A2Y9HJ20
uniprot id: A0A8M1M7T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DZIP C2H2-type zinc-finger protein family.
messages: centriole
messages: cilium basal body

29088:LOC110586608
gene id: 29088:LOC110586608
uniprot id: A0A2Y9HRX8
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

29088:DNAJA4
gene id: 29088:DNAJA4
uniprot id: A0A2Y9GBL0
names: Subcellular Location Annotation
messages: Membrane

29088:GTF2B
gene id: 29088:GTF2B
uniprot id: A0A2Y9H267
uniprot id: A0A2Y9H2A8
names: Similarity
messages: Belongs to the TFIIB family.

29088:GABARAPL2
gene id: 29088:GABARAPL2
uniprot id: A0A2Y9ICE5
names: Similarity
messages: Belongs to the ATG8 family.

29088:LOC110570538
gene id: 29088:LOC110570538
uniprot id: A0A2Y9G7W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:PSMF1
gene id: 29088:PSMF1
uniprot id: A0A2Y9GZ95
uniprot id: A0A8M1ML11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome inhibitor PI31 family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.

29088:GDPD2
gene id: 29088:GDPD2
uniprot id: A0A2Y9GAK9
uniprot id: A0A2Y9GAL4
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

29088:LOC110573235
gene id: 29088:LOC110573235
uniprot id: A0A2Y9GE66
uniprot id: A0A2Y9GE90
uniprot id: A0A2Y9GHA3
uniprot id: A0A2Y9GIS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synuclein family.
messages: Membrane
messages: Nucleus
messages: Secreted
messages: Synapse
messages: axon

29088:ACTC1
gene id: 29088:ACTC1
uniprot id: A0A2Y9HN35
uniprot id: A0A2Y9HNF0
names: Similarity
messages: Belongs to the actin family.

29088:MPV17
gene id: 29088:MPV17
uniprot id: A0A2Y9HNE4
uniprot id: A0A8M1MLF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

29088:LOC110581327
gene id: 29088:LOC110581327
uniprot id: A0A8M1MVL3
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

29088:RNF157
gene id: 29088:RNF157
uniprot id: A0A8M1MWZ0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

29088:NPY5R
gene id: 29088:NPY5R
uniprot id: A0A2Y9HSS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane
messages: Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.

29088:AHSA1
gene id: 29088:AHSA1
uniprot id: A0A2Y9GAZ1
names: Similarity
messages: Belongs to the AHA1 family.

29088:LOC110592612
gene id: 29088:LOC110592612
uniprot id: A0A2Y9IAP2
uniprot id: A0A8M1MSF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

29088:TMC6
gene id: 29088:TMC6
uniprot id: A0A2Y9GC99
uniprot id: A0A2Y9GCA4
uniprot id: A0A2Y9GCC0
uniprot id: A0A2Y9GF27
uniprot id: A0A8M1MVK1
uniprot id: A0A8M1MXU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

29088:PEA15
gene id: 29088:PEA15
uniprot id: A0A2Y9GEQ2
names: Subcellular Location Annotation
messages: Cytoplasm

29088:CHST4
gene id: 29088:CHST4
uniprot id: A0A2Y9IB35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

29088:LOC110584533
gene id: 29088:LOC110584533
uniprot id: A0A2Y9HEX7
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

29088:DRD1
gene id: 29088:DRD1
uniprot id: A0A2Y9HQY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
messages: Membrane
messages: dendritic spine

29088:LOC110576179
gene id: 29088:LOC110576179
uniprot id: A0A2Y9GNZ6
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110587623
gene id: 29088:LOC110587623
uniprot id: A0A8M1M5R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

29088:ADIPOR1
gene id: 29088:ADIPOR1
uniprot id: A0A8M1MEM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

29088:CRHR2
gene id: 29088:CRHR2
uniprot id: A0A2Y9H1C6
uniprot id: A0A2Y9H658
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

29088:LOC110575893
gene id: 29088:LOC110575893
uniprot id: A0A2Y9GN81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Midbody
messages: Nucleus
messages: kinetochore
messages: spindle

29088:HSPA4
gene id: 29088:HSPA4
uniprot id: A0A2Y9I1I1
uniprot id: A0A8M1MGU8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Interacts with TJP1/ZO-1.

29088:ZC3HC1
gene id: 29088:ZC3HC1
uniprot id: A0A2Y9HTU7
uniprot id: A0A8M1MTA3
names: Subcellular Location Annotation
messages: Nucleus

29088:TRAPPC2
gene id: 29088:TRAPPC2
uniprot id: A0A8M1M9L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

29088:EIF4G1
gene id: 29088:EIF4G1
uniprot id: A0A2Y9H947
uniprot id: A0A2Y9H982
uniprot id: A0A2Y9H9D2
uniprot id: A0A2Y9HEZ8
uniprot id: A0A8M1MQ31
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

29088:UGT3A2
gene id: 29088:UGT3A2
uniprot id: A0A8M1MGD1
uniprot id: A0A8M1MGD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

29088:EPHB1
gene id: 29088:EPHB1
uniprot id: A0A8M1MFW8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: dendrite

29088:ART5
gene id: 29088:ART5
uniprot id: A0A2Y9I9F0
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

29088:ARX
gene id: 29088:ARX
uniprot id: A0A8M1M8U5
names: Subcellular Location Annotation
messages: Nucleus

29088:TTC4
gene id: 29088:TTC4
uniprot id: A0A2Y9GLB3
uniprot id: A0A2Y9GLL8
names: Similarity
messages: Belongs to the TTC4 family.

29088:LOC110576401
gene id: 29088:LOC110576401
uniprot id: A0A2Y9GPR4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

29088:LOC110577120
gene id: 29088:LOC110577120
uniprot id: A0A2Y9GW25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

29088:TNP2
gene id: 29088:TNP2
uniprot id: A0A2Y9HQ28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear transition protein 2 family.
messages: Nucleus
messages: Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.

29088:SPIN4
gene id: 29088:SPIN4
uniprot id: A0A2Y9G5J3
names: Similarity
messages: Belongs to the SPIN/STSY family.

29088:LOC110585985
gene id: 29088:LOC110585985
uniprot id: A0A2Y9HJ49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxin-19 family.
messages: Interacts with a broad range of peroxisomal membrane proteins, including PEX3, PEX10, PEX11A, PEX11B, PEX12, PEX13, PEX14 and PEX16, PXMP2/PMP22, PXMP4/PMP24, SLC25A17/PMP34, ABCD1/ALDP, ABCD2/ALDRP, and ABCD3/PMP70. Also interacts with the tumor suppressor CDKN2A/p19ARF.
messages: Membrane
messages: Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.
messages: Peroxisome membrane

29088:KRT32
gene id: 29088:KRT32
uniprot id: A0A2Y9GEH5
names: Similarity
messages: Belongs to the intermediate filament family.

29088:GINS4
gene id: 29088:GINS4
uniprot id: A0A2Y9GGU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Chromosome
messages: Nucleus
messages: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

29088:PPP3CC
gene id: 29088:PPP3CC
uniprot id: A0A2Y9HSH1
uniprot id: A0A2Y9HXV8
uniprot id: A0A2Y9HZE9
uniprot id: A0A8M1M6Y4
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

29088:LOC110581711
gene id: 29088:LOC110581711
uniprot id: A0A2Y9H6P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:E2F3
gene id: 29088:E2F3
uniprot id: A0A2Y9HS45
uniprot id: A0A2Y9HTA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

29088:ETV3
gene id: 29088:ETV3
uniprot id: A0A2Y9GF19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus
messages: Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity.

29088:SUSD5
gene id: 29088:SUSD5
uniprot id: A0A2Y9G2G7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ELP6
gene id: 29088:ELP6
uniprot id: A0A2Y9GTY0
names: Similarity
messages: Belongs to the ELP6 family.

29088:CD48
gene id: 29088:CD48
uniprot id: A0A2Y9GEP2
uniprot id: A0A2Y9GET4
uniprot id: A0A2Y9GET6
names: Subcellular Location Annotation
messages: Membrane

29088:ATP5F1E
gene id: 29088:ATP5F1E
uniprot id: A0A2Y9G6S8
names: Function
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

29088:PIP4P1
gene id: 29088:PIP4P1
uniprot id: A0A2Y9HI72
uniprot id: A0A2Y9HPG2
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: phagosome membrane

29088:SNTG1
gene id: 29088:SNTG1
uniprot id: A0A2Y9H257
uniprot id: A0A2Y9H4A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

29088:LOC110593607
gene id: 29088:LOC110593607
uniprot id: A0A2Y9IDV3
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion membrane

29088:GALNT13
gene id: 29088:GALNT13
uniprot id: A0A2Y9I3X3
uniprot id: A0A2Y9I8I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

29088:LOC123324838
gene id: 29088:LOC123324838
uniprot id: A0A8M1MDZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMCO1 family.
messages: Calcium-selective channel required to prevent calcium stores from overfilling.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer and homotetramer. Homodimer under resting conditions; forms homotetramers following and ER calcium overload.
messages: Membrane

29088:EWSR1
gene id: 29088:EWSR1
uniprot id: A0A2Y9ICS5
uniprot id: A0A8M1MWE9
uniprot id: A0A8M1MYW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

29088:DNASE1L2
gene id: 29088:DNASE1L2
uniprot id: A0A2Y9HWX9
names: Similarity
messages: Belongs to the DNase I family.

29088:MFSD3
gene id: 29088:MFSD3
uniprot id: A0A2Y9H4N0
names: Subcellular Location Annotation
messages: Membrane

29088:LOC110578007
gene id: 29088:LOC110578007
uniprot id: A0A8M1M9Y0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

29088:MRPL20
gene id: 29088:MRPL20
uniprot id: A0A2Y9GIM2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

29088:PDE11A
gene id: 29088:PDE11A
uniprot id: A0A2Y9I425
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

29088:MCUR1
gene id: 29088:MCUR1
uniprot id: A0A2Y9HLD9
uniprot id: A0A2Y9HSZ4
names: Similarity
messages: Belongs to the CCDC90 family.

29088:GABRG2
gene id: 29088:GABRG2
uniprot id: A0A2Y9HQ43
uniprot id: A0A2Y9HWH3
uniprot id: A0A8M1MI67
uniprot id: A0A8M1MJI1
uniprot id: A0A8M1MPX0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

29088:FAM91A1
gene id: 29088:FAM91A1
uniprot id: A0A2Y9H3A2
names: Similarity
messages: Belongs to the FAM91 family.

29088:PIGN
gene id: 29088:PIGN
uniprot id: A0A2Y9GS10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
messages: Membrane

29088:LOC110593359
gene id: 29088:LOC110593359
uniprot id: A0A2Y9IFX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

29088:MMP27
gene id: 29088:MMP27
uniprot id: A0A2Y9HK80
names: Similarity
messages: Belongs to the peptidase M10A family.

29088:BBS5
gene id: 29088:BBS5
uniprot id: A0A8M1ME21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BBS5 family.
messages: Membrane
messages: Part of BBSome complex, that contains BBS1, BBS2, BBS4, BBS5, BBS7, BBS8/TTC8, BBS9 and BBIP10.
messages: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for BBSome complex ciliary localization but not for the proper complex assembly.
messages: centriolar satellite
messages: cilium membrane

29088:OLFML2B
gene id: 29088:OLFML2B
uniprot id: A0A2Y9HQR8
uniprot id: A0A2Y9HR40
uniprot id: A0A2Y9HR63
uniprot id: A0A2Y9HW07
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

29088:ABI3
gene id: 29088:ABI3
uniprot id: A0A2Y9IC12
uniprot id: A0A2Y9IER1
names: Similarity
messages: Belongs to the ABI family.

29088:TOMM40
gene id: 29088:TOMM40
uniprot id: A0A2Y9GD92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

29088:MMP20
gene id: 29088:MMP20
uniprot id: A0A2Y9HR19
names: Similarity
messages: Belongs to the peptidase M10A family.

29088:CRHR1
gene id: 29088:CRHR1
uniprot id: A0A2Y9G595
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
messages: Membrane

29088:GAS8
gene id: 29088:GAS8
uniprot id: A0A2Y9IFU9
uniprot id: A0A2Y9IIX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: flagellum axoneme

29088:CNN3
gene id: 29088:CNN3
uniprot id: A0A2Y9H320
uniprot id: A0A8M1M818
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

29088:GCG
gene id: 29088:GCG
uniprot id: A0A2Y9I4H7
uniprot id: A0A2Y9I553
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

29088:TMCO3
gene id: 29088:TMCO3
uniprot id: A0A2Y9HIP4
uniprot id: A0A2Y9HPQ9
names: Subcellular Location Annotation
messages: Membrane

29088:LSM6
gene id: 29088:LSM6
uniprot id: A0A2Y9GA24
uniprot id: A0A2Y9GB27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

29088:LOC110589350
gene id: 29088:LOC110589350
uniprot id: A0A2Y9HVJ6
names: Similarity
messages: Belongs to the cytochrome P450 family.

29088:AMPD2
gene id: 29088:AMPD2
uniprot id: A0A2Y9H2T5
uniprot id: A0A2Y9H2V1
uniprot id: A0A2Y9H2W7
uniprot id: A0A2Y9H7V2
uniprot id: A0A8M1MBW1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

29088:SF3B1
gene id: 29088:SF3B1
uniprot id: A0A2Y9I5C6
uniprot id: A0A2Y9IBZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

29088:YIPF4
gene id: 29088:YIPF4
uniprot id: A0A2Y9HMX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

29088:LOC110591054
gene id: 29088:LOC110591054
uniprot id: A0A2Y9I1F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

29088:ALKBH8
gene id: 29088:ALKBH8
uniprot id: A0A8M1MNH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkB family.
messages: Cytoplasm

29088:TCTN1
gene id: 29088:TCTN1
uniprot id: A0A2Y9HRJ0
uniprot id: A0A2Y9HRY9
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

29088:ARL8B
gene id: 29088:ARL8B
uniprot id: A0A2Y9HFN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Synapse
messages: spindle

29088:LOC110580592
gene id: 29088:LOC110580592
uniprot id: A0A2Y9H7W2
names: Subcellular Location Annotation
messages: Nucleus

29088:LOC110585538
gene id: 29088:LOC110585538
uniprot id: A0A8M1MNG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

29088:ELMO2
gene id: 29088:ELMO2
uniprot id: A0A8M1MM64
uniprot id: A0A8M1MM66
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

29088:DDB2
gene id: 29088:DDB2
uniprot id: A0A8M1MNG0
uniprot id: A0A8M1MRQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Nucleus