290512:PAES RS11680
gene id: 290512:PAES_RS11680
uniprot id: B4S9L7
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS02165
gene id: 290512:PAES_RS02165
uniprot id: B4S4Y9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

290512:PAES RS08440
gene id: 290512:PAES_RS08440
uniprot id: B4S3G8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

290512:PAES RS04405
gene id: 290512:PAES_RS04405
uniprot id: B4S785
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

290512:PAES RS10900
gene id: 290512:PAES_RS10900
uniprot id: B4S690
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

290512:PAES RS03750
gene id: 290512:PAES_RS03750
uniprot id: B4S6P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

290512:PAES RS04290
gene id: 290512:PAES_RS04290
uniprot id: B4S762
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

290512:PAES RS11305
gene id: 290512:PAES_RS11305
uniprot id: B4S6R8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

290512:PAES RS10480
gene id: 290512:PAES_RS10480
uniprot id: B4S5R5
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

290512:PAES RS00425
gene id: 290512:PAES_RS00425
uniprot id: B4S355
names: Similarity
messages: Belongs to the YjdM family.

290512:PAES RS06925
gene id: 290512:PAES_RS06925
uniprot id: B4S8L6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

290512:PAES RS10560
gene id: 290512:PAES_RS10560
uniprot id: B4S5S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

290512:PAES RS03430
gene id: 290512:PAES_RS03430
uniprot id: B4S6I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

290512:PAES RS08290
gene id: 290512:PAES_RS08290
uniprot id: B4S3D8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

290512:PAES RS07870
gene id: 290512:PAES_RS07870
uniprot id: B4S9C3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS11600
gene id: 290512:PAES_RS11600
uniprot id: B4S6X4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

290512:PAES RS03715
gene id: 290512:PAES_RS03715
uniprot id: B4S6N3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

290512:PAES RS10515
gene id: 290512:PAES_RS10515
uniprot id: B4S5S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

290512:PAES RS11080
gene id: 290512:PAES_RS11080
uniprot id: B4S6C8
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

290512:PAES RS00015
gene id: 290512:PAES_RS00015
uniprot id: B4S937
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

290512:PAES RS01235
gene id: 290512:PAES_RS01235
uniprot id: B4S3V9
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

290512:PAES RS11285
gene id: 290512:PAES_RS11285
uniprot id: B4S6R4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS04015
gene id: 290512:PAES_RS04015
uniprot id: B4S715
names: Similarity
messages: Belongs to the TrpF family.

290512:PAES RS02050
gene id: 290512:PAES_RS02050
uniprot id: B4S4W5
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS06910
gene id: 290512:PAES_RS06910
uniprot id: B4S8L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

290512:PAES RS10645
gene id: 290512:PAES_RS10645
uniprot id: B4S5U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

290512:PAES RS00870
gene id: 290512:PAES_RS00870
uniprot id: B4S3N6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

290512:PAES RS05535
gene id: 290512:PAES_RS05535
uniprot id: B4S7V0
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

290512:PAES RS01430
gene id: 290512:PAES_RS01430
uniprot id: B4S493
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

290512:PAES RS06890
gene id: 290512:PAES_RS06890
uniprot id: B4S8K9
names: Similarity
messages: Belongs to the SAICAR synthetase family.

290512:PAES RS05855
gene id: 290512:PAES_RS05855
uniprot id: B4S811
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

290512:PAES RS08495
gene id: 290512:PAES_RS08495
uniprot id: B4S3H9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

290512:PAES RS07515
gene id: 290512:PAES_RS07515
uniprot id: B4S8Y5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

290512:PAES RS01875
gene id: 290512:PAES_RS01875
uniprot id: B4S4T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

290512:PAES RS10270
gene id: 290512:PAES_RS10270
uniprot id: B4S5C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

290512:PAES RS04685
gene id: 290512:PAES_RS04685
uniprot id: B4S7D5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS10745
gene id: 290512:PAES_RS10745
uniprot id: B4S5W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

290512:PAES RS01320
gene id: 290512:PAES_RS01320
uniprot id: B4S3X8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

290512:PAES RS00550
gene id: 290512:PAES_RS00550
uniprot id: B4S380
names: Similarity
messages: Belongs to the asparagine synthetase family.

290512:PAES RS00875
gene id: 290512:PAES_RS00875
uniprot id: B4S3N7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

290512:PAES RS04590
gene id: 290512:PAES_RS04590
uniprot id: B4S7B7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

290512:PAES RS09115
gene id: 290512:PAES_RS09115
uniprot id: B4S447
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

290512:PAES RS00250
gene id: 290512:PAES_RS00250
uniprot id: B4S984
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

290512:PAES RS10165
gene id: 290512:PAES_RS10165
uniprot id: B4S5A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

290512:PAES RS09800
gene id: 290512:PAES_RS09800
uniprot id: B4S530
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS06455
gene id: 290512:PAES_RS06455
uniprot id: B4S8C6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

290512:PAES RS06730
gene id: 290512:PAES_RS06730
uniprot id: B4S8H9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

290512:PAES RS08305
gene id: 290512:PAES_RS08305
uniprot id: B4S3E1
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

290512:PAES RS07885
gene id: 290512:PAES_RS07885
uniprot id: B4S9C6
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS04615
gene id: 290512:PAES_RS04615
uniprot id: B4S7C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

290512:PAES RS08095
gene id: 290512:PAES_RS08095
uniprot id: B4S9G8
names: Similarity
messages: Belongs to the XFP family.

290512:PAES RS07705
gene id: 290512:PAES_RS07705
uniprot id: B4S924
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

290512:PAES RS08930
gene id: 290512:PAES_RS08930
uniprot id: B4S410
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

290512:PAES RS02500
gene id: 290512:PAES_RS02500
uniprot id: B4S5G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

290512:PAES RS01840
gene id: 290512:PAES_RS01840
uniprot id: B4S4S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

290512:PAES RS11585
gene id: 290512:PAES_RS11585
uniprot id: B4S6X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

290512:PAES RS08785
gene id: 290512:PAES_RS08785
uniprot id: B4S3Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

290512:PAES RS09825
gene id: 290512:PAES_RS09825
uniprot id: B4S535
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

290512:PAES RS05465
gene id: 290512:PAES_RS05465
uniprot id: B4S7T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

290512:PAES RS00835
gene id: 290512:PAES_RS00835
uniprot id: B4S3D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

290512:PAES RS01555
gene id: 290512:PAES_RS01555
uniprot id: B4S4C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

290512:PAES RS04655
gene id: 290512:PAES_RS04655
uniprot id: B4S7C9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

290512:PAES RS07185
gene id: 290512:PAES_RS07185
uniprot id: B4S8S1
names: Function
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.
messages: Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.

290512:PAES RS03585
gene id: 290512:PAES_RS03585
uniprot id: B4S6K8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

290512:PAES RS04105
gene id: 290512:PAES_RS04105
uniprot id: B4S727
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

290512:PAES RS09065
gene id: 290512:PAES_RS09065
uniprot id: B4S436
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

290512:PAES RS09430
gene id: 290512:PAES_RS09430
uniprot id: B4S4K5
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

290512:PAES RS02850
gene id: 290512:PAES_RS02850
uniprot id: B4S5X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

290512:PAES RS03395
gene id: 290512:PAES_RS03395
uniprot id: B4S6H3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

290512:PAES RS03020
gene id: 290512:PAES_RS03020
uniprot id: B4S611
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

290512:PAES RS10830
gene id: 290512:PAES_RS10830
uniprot id: B4S676
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

290512:PAES RS03310
gene id: 290512:PAES_RS03310
uniprot id: B4S6G0
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

290512:PAES RS10370
gene id: 290512:PAES_RS10370
uniprot id: B4S5P3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

290512:PAES RS07300
gene id: 290512:PAES_RS07300
uniprot id: B4S8U5
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

290512:PAES RS11345
gene id: 290512:PAES_RS11345
uniprot id: B4S6S6
names: Similarity
messages: Belongs to the peptidase S8 family.

290512:PAES RS08250
gene id: 290512:PAES_RS08250
uniprot id: B4S9J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

290512:PAES RS06505
gene id: 290512:PAES_RS06505
uniprot id: B4S8D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

290512:PAES RS06720
gene id: 290512:PAES_RS06720
uniprot id: B4S8H7
names: Similarity
messages: Belongs to the P(II) protein family.

290512:PAES RS02945
gene id: 290512:PAES_RS02945
uniprot id: B4S5Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

290512:PAES RS09275
gene id: 290512:PAES_RS09275
uniprot id: B4S4H5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

290512:PAES RS09515
gene id: 290512:PAES_RS09515
uniprot id: B4S4M2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS05185
gene id: 290512:PAES_RS05185
uniprot id: B4S7N3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

290512:PAES RS08725
gene id: 290512:PAES_RS08725
uniprot id: B4S3M5
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

290512:PAES RS00510
gene id: 290512:PAES_RS00510
uniprot id: B4S372
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS02480
gene id: 290512:PAES_RS02480
uniprot id: B4S5F6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

290512:PAES RS01985
gene id: 290512:PAES_RS01985
uniprot id: B4S4V2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

290512:PAES RS02075
gene id: 290512:PAES_RS02075
uniprot id: B4S4X0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

290512:PAES RS10845
gene id: 290512:PAES_RS10845
uniprot id: B4S679
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

290512:PAES RS01160
gene id: 290512:PAES_RS01160
uniprot id: B4S3U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

290512:PAES RS07010
gene id: 290512:PAES_RS07010
uniprot id: B4S8N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

290512:PAES RS10205
gene id: 290512:PAES_RS10205
uniprot id: B4S5B1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

290512:PAES RS07380
gene id: 290512:PAES_RS07380
uniprot id: B4S8V9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

290512:PAES RS02715
gene id: 290512:PAES_RS02715
uniprot id: B4S5K5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

290512:PAES RS07310
gene id: 290512:PAES_RS07310
uniprot id: B4S8U7
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

290512:PAES RS10260
gene id: 290512:PAES_RS10260
uniprot id: B4S5C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

290512:PAES RS07435
gene id: 290512:PAES_RS07435
uniprot id: B4S8X0
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS06055
gene id: 290512:PAES_RS06055
uniprot id: B4S851
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

290512:PAES RS03245
gene id: 290512:PAES_RS03245
uniprot id: B4S652
names: Similarity
messages: Belongs to the peptidase M1 family.

290512:PAES RS09200
gene id: 290512:PAES_RS09200
uniprot id: B4S464
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

290512:PAES RS07710
gene id: 290512:PAES_RS07710
uniprot id: B4S925
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

290512:PAES RS10300
gene id: 290512:PAES_RS10300
uniprot id: B4S5M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

290512:PAES RS02310
gene id: 290512:PAES_RS02310
uniprot id: B4S520
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

290512:PAES RS01480
gene id: 290512:PAES_RS01480
uniprot id: B4S4A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

290512:PAES RS00140
gene id: 290512:PAES_RS00140
uniprot id: B4S962
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

290512:PAES RS09185
gene id: 290512:PAES_RS09185
uniprot id: B4S461
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

290512:PAES RS08515
gene id: 290512:PAES_RS08515
uniprot id: B4S3I3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

290512:PAES RS11645
gene id: 290512:PAES_RS11645
uniprot id: B4S9L0
names: Similarity
messages: Belongs to the GSP E family.

290512:PAES RS05240
gene id: 290512:PAES_RS05240
uniprot id: B4S7P4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

290512:PAES RS08140
gene id: 290512:PAES_RS08140
uniprot id: B4S9H7
names: Similarity
messages: Belongs to the P(II) protein family.

290512:PAES RS05425
gene id: 290512:PAES_RS05425
uniprot id: B4S7S7
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS06705
gene id: 290512:PAES_RS06705
uniprot id: B4S8H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

290512:PAES RS07570
gene id: 290512:PAES_RS07570
uniprot id: B4S8Z6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

290512:PAES RS08735
gene id: 290512:PAES_RS08735
uniprot id: B4S3M7
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS06850
gene id: 290512:PAES_RS06850
uniprot id: B4S8K1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

290512:PAES RS00065
gene id: 290512:PAES_RS00065
uniprot id: B4S947
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

290512:PAES RS10875
gene id: 290512:PAES_RS10875
uniprot id: B4S685
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

290512:PAES RS01950
gene id: 290512:PAES_RS01950
uniprot id: B4S4U7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

290512:PAES RS04760
gene id: 290512:PAES_RS04760
uniprot id: B4S7F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

290512:PAES RS01640
gene id: 290512:PAES_RS01640
uniprot id: B4S4D6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

290512:PAES RS02835
gene id: 290512:PAES_RS02835
uniprot id: B4S5X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

290512:PAES RS01890
gene id: 290512:PAES_RS01890
uniprot id: B4S4T5
names: Subcellular Location Annotation
messages: Cytoplasm

290512:PAES RS02150
gene id: 290512:PAES_RS02150
uniprot id: B4S4Y6
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

290512:PAES RS08955
gene id: 290512:PAES_RS08955
uniprot id: B4S415
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

290512:PAES RS04240
gene id: 290512:PAES_RS04240
uniprot id: B4S752
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

290512:PAES RS05220
gene id: 290512:PAES_RS05220
uniprot id: B4S7P0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS02210
gene id: 290512:PAES_RS02210
uniprot id: B4S4Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

290512:PAES RS10950
gene id: 290512:PAES_RS10950
uniprot id: B4S6A1
names: Similarity
messages: Belongs to the peptidase S24 family.

290512:PAES RS00610
gene id: 290512:PAES_RS00610
uniprot id: B4S391
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

290512:PAES RS09960
gene id: 290512:PAES_RS09960
uniprot id: B4S561
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

290512:PAES RS03710
gene id: 290512:PAES_RS03710
uniprot id: B4S6N2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

290512:PAES RS07535
gene id: 290512:PAES_RS07535
uniprot id: B4S8Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

290512:PAES RS10665
gene id: 290512:PAES_RS10665
uniprot id: B4S5U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

290512:PAES RS07745
gene id: 290512:PAES_RS07745
uniprot id: B4S932
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

290512:PAES RS08965
gene id: 290512:PAES_RS08965
uniprot id: B4S416
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

290512:PAES RS04400
gene id: 290512:PAES_RS04400
uniprot id: B4S784
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

290512:PAES RS00535
gene id: 290512:PAES_RS00535
uniprot id: B4S377
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

290512:PAES RS03595
gene id: 290512:PAES_RS03595
uniprot id: B4S6L0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

290512:PAES RS10965
gene id: 290512:PAES_RS10965
uniprot id: B4S6A4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

290512:PAES RS06750
gene id: 290512:PAES_RS06750
uniprot id: B4S8I3
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS04330
gene id: 290512:PAES_RS04330
uniprot id: B4S770
names: Similarity
messages: Belongs to the thioredoxin family.

290512:PAES RS03030
gene id: 290512:PAES_RS03030
uniprot id: B4S613
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

290512:PAES RS04280
gene id: 290512:PAES_RS04280
uniprot id: B4S760
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

290512:PAES RS01570
gene id: 290512:PAES_RS01570
uniprot id: B4S4C3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

290512:PAES RS09710
gene id: 290512:PAES_RS09710
uniprot id: B4S4R2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

290512:PAES RS11660
gene id: 290512:PAES_RS11660
uniprot id: B4S9L3
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

290512:PAES RS06360
gene id: 290512:PAES_RS06360
uniprot id: B4S8A6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

290512:PAES RS02285
gene id: 290512:PAES_RS02285
uniprot id: B4S515
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

290512:PAES RS11715
gene id: 290512:PAES_RS11715
uniprot id: B4S9M5
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

290512:PAES RS00900
gene id: 290512:PAES_RS00900
uniprot id: B4S3P2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

290512:PAES RS01440
gene id: 290512:PAES_RS01440
uniprot id: B4S495
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

290512:PAES RS00450
gene id: 290512:PAES_RS00450
uniprot id: B4S360
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

290512:PAES RS11265
gene id: 290512:PAES_RS11265
uniprot id: B4S6R0
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS05470
gene id: 290512:PAES_RS05470
uniprot id: B4S7T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

290512:PAES RS08505
gene id: 290512:PAES_RS08505
uniprot id: B4S3I1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS05885
gene id: 290512:PAES_RS05885
uniprot id: B4S817
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

290512:PAES RS01660
gene id: 290512:PAES_RS01660
uniprot id: B4S4E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

290512:PAES RS09415
gene id: 290512:PAES_RS09415
uniprot id: B4S4K2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

290512:PAES RS10625
gene id: 290512:PAES_RS10625
uniprot id: B4S5U0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

290512:PAES RS03995
gene id: 290512:PAES_RS03995
uniprot id: B4S710
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

290512:PAES RS02485
gene id: 290512:PAES_RS02485
uniprot id: B4S5F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

290512:PAES RS05550
gene id: 290512:PAES_RS05550
uniprot id: B4S7V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

290512:PAES RS08395
gene id: 290512:PAES_RS08395
uniprot id: B4S3F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

290512:PAES RS09780
gene id: 290512:PAES_RS09780
uniprot id: P15528
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BChl C/E-binding protein family.
messages: Component of the photosynthetic apparatus. The light harvesting B740 complex binds bacteriochlorophyll c.
messages: chlorosome envelope

290512:PAES RS08830
gene id: 290512:PAES_RS08830
uniprot id: B4S3Z0
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS06585
gene id: 290512:PAES_RS06585
uniprot id: B4S8F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

290512:PAES RS10200
gene id: 290512:PAES_RS10200
uniprot id: B4S5B0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

290512:PAES RS04525
gene id: 290512:PAES_RS04525
uniprot id: B4S7A4
names: Similarity
messages: Belongs to the CFA/CMAS family.

290512:PAES RS10820
gene id: 290512:PAES_RS10820
uniprot id: B4S674
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

290512:PAES RS01250
gene id: 290512:PAES_RS01250
uniprot id: B4S3W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

290512:PAES RS07735
gene id: 290512:PAES_RS07735
uniprot id: B4S930
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

290512:PAES RS03770
gene id: 290512:PAES_RS03770
uniprot id: B4S6P4
names: Similarity
messages: Belongs to the Pal lipoprotein family.

290512:PAES RS08360
gene id: 290512:PAES_RS08360
uniprot id: B4S3F2
names: Similarity
messages: Belongs to the RecJ family.

290512:PAES RS08710
gene id: 290512:PAES_RS08710
uniprot id: B4S3M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

290512:PAES RS05390
gene id: 290512:PAES_RS05390
uniprot id: B4S7S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

290512:PAES RS07345
gene id: 290512:PAES_RS07345
uniprot id: B4S8V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

290512:PAES RS00245
gene id: 290512:PAES_RS00245
uniprot id: B4S983
names: Similarity
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

290512:PAES RS09100
gene id: 290512:PAES_RS09100
uniprot id: B4S444
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

290512:PAES RS04110
gene id: 290512:PAES_RS04110
uniprot id: B4S729
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

290512:PAES RS11300
gene id: 290512:PAES_RS11300
uniprot id: B4S6R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

290512:PAES RS10905
gene id: 290512:PAES_RS10905
uniprot id: B4S691
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

290512:PAES RS06365
gene id: 290512:PAES_RS06365
uniprot id: B4S8A7
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

290512:PAES RS07600
gene id: 290512:PAES_RS07600
uniprot id: B4S903
names: Similarity
messages: Belongs to the UPF0047 family.

290512:PAES RS06700
gene id: 290512:PAES_RS06700
uniprot id: B4S8H3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

290512:PAES RS08005
gene id: 290512:PAES_RS08005
uniprot id: B4S9F0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

290512:PAES RS00305
gene id: 290512:PAES_RS00305
uniprot id: B4S994
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

290512:PAES RS08585
gene id: 290512:PAES_RS08585
uniprot id: B4S3J6
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

290512:PAES RS07580
gene id: 290512:PAES_RS07580
uniprot id: B4S8Z9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

290512:PAES RS08115
gene id: 290512:PAES_RS08115
uniprot id: B4S9H2
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

290512:PAES RS01915
gene id: 290512:PAES_RS01915
uniprot id: B4S4U0
names: Similarity
messages: Belongs to the Skp family.

290512:PAES RS06265
gene id: 290512:PAES_RS06265
uniprot id: B4S889
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS10510
gene id: 290512:PAES_RS10510
uniprot id: B4S5R9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

290512:PAES RS07275
gene id: 290512:PAES_RS07275
uniprot id: B4S8U0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

290512:PAES RS07695
gene id: 290512:PAES_RS07695
uniprot id: B4S922
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

290512:PAES RS06285
gene id: 290512:PAES_RS06285
uniprot id: B4S893
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

290512:PAES RS10620
gene id: 290512:PAES_RS10620
uniprot id: B4S5T9
names: Similarity
messages: Belongs to the universal stress protein A family.

290512:PAES RS02645
gene id: 290512:PAES_RS02645
uniprot id: B4S5J0
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

290512:PAES RS00205
gene id: 290512:PAES_RS00205
uniprot id: B4S975
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

290512:PAES RS09445
gene id: 290512:PAES_RS09445
uniprot id: B4S4K8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS02940
gene id: 290512:PAES_RS02940
uniprot id: B4S5Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

290512:PAES RS11570
gene id: 290512:PAES_RS11570
uniprot id: B4S6W8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

290512:PAES RS05960
gene id: 290512:PAES_RS05960
uniprot id: B4S833
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

290512:PAES RS08265
gene id: 290512:PAES_RS08265
uniprot id: B4S9K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

290512:PAES RS01845
gene id: 290512:PAES_RS01845
uniprot id: B4S4S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

290512:PAES RS02595
gene id: 290512:PAES_RS02595
uniprot id: B4S5H8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

290512:PAES RS06935
gene id: 290512:PAES_RS06935
uniprot id: B4S8L8
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS04765
gene id: 290512:PAES_RS04765
uniprot id: B4S7F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

290512:PAES RS10235
gene id: 290512:PAES_RS10235
uniprot id: B4S5B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

290512:PAES RS07795
gene id: 290512:PAES_RS07795
uniprot id: B4S9A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PucC family.
messages: Membrane

290512:PAES RS02495
gene id: 290512:PAES_RS02495
uniprot id: B4S5F9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

290512:PAES RS00830
gene id: 290512:PAES_RS00830
uniprot id: B4S3D0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

290512:PAES RS03725
gene id: 290512:PAES_RS03725
uniprot id: B4S6N5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

290512:PAES RS10175
gene id: 290512:PAES_RS10175
uniprot id: B4S5A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

290512:PAES RS07400
gene id: 290512:PAES_RS07400
uniprot id: B4S8W3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

290512:PAES RS09990
gene id: 290512:PAES_RS09990
uniprot id: B4S566
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

290512:PAES RS10275
gene id: 290512:PAES_RS10275
uniprot id: B4S5M3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

290512:PAES RS03405
gene id: 290512:PAES_RS03405
uniprot id: B4S6H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

290512:PAES RS11000
gene id: 290512:PAES_RS11000
uniprot id: B4S6B2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

290512:PAES RS03650
gene id: 290512:PAES_RS03650
uniprot id: B4S6M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

290512:PAES RS05890
gene id: 290512:PAES_RS05890
uniprot id: B4S818
names: Similarity
messages: Belongs to the sigma-54 factor family.

290512:PAES RS07820
gene id: 290512:PAES_RS07820
uniprot id: B4S9B3
names: Subcellular Location Annotation
messages: Periplasm

290512:PAES RS10305
gene id: 290512:PAES_RS10305
uniprot id: B4S5M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

290512:PAES RS08030
gene id: 290512:PAES_RS08030
uniprot id: B4S9F5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

290512:PAES RS09285
gene id: 290512:PAES_RS09285
uniprot id: B4S4H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

290512:PAES RS10130
gene id: 290512:PAES_RS10130
uniprot id: B4S595
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

290512:PAES RS01395
gene id: 290512:PAES_RS01395
uniprot id: B4S490
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

290512:PAES RS10320
gene id: 290512:PAES_RS10320
uniprot id: B4S5N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

290512:PAES RS03515
gene id: 290512:PAES_RS03515
uniprot id: B4S6J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

290512:PAES RS10115
gene id: 290512:PAES_RS10115
uniprot id: B4S592
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

290512:PAES RS08945
gene id: 290512:PAES_RS08945
uniprot id: B4S413
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

290512:PAES RS07940
gene id: 290512:PAES_RS07940
uniprot id: B4S9D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

290512:PAES RS08345
gene id: 290512:PAES_RS08345
uniprot id: B4S3E9
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS06470
gene id: 290512:PAES_RS06470
uniprot id: B4S8C9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

290512:PAES RS08255
gene id: 290512:PAES_RS08255
uniprot id: B4S9K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

290512:PAES RS02870
gene id: 290512:PAES_RS02870
uniprot id: B4S5Y1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

290512:PAES RS07075
gene id: 290512:PAES_RS07075
uniprot id: B4S8P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

290512:PAES RS04830
gene id: 290512:PAES_RS04830
uniprot id: B4S7G4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

290512:PAES RS06400
gene id: 290512:PAES_RS06400
uniprot id: B4S8B4
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

290512:PAES RS05060
gene id: 290512:PAES_RS05060
uniprot id: B4S7K9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS02315
gene id: 290512:PAES_RS02315
uniprot id: B4S521
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS10125
gene id: 290512:PAES_RS10125
uniprot id: B4S594
names: Similarity
messages: Belongs to the UPF0045 family.

290512:PAES RS07005
gene id: 290512:PAES_RS07005
uniprot id: B4S8N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

290512:PAES RS09205
gene id: 290512:PAES_RS09205
uniprot id: B4S465
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS08160
gene id: 290512:PAES_RS08160
uniprot id: B4S9I1
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

290512:PAES RS03805
gene id: 290512:PAES_RS03805
uniprot id: B4S6Q1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

290512:PAES RS09175
gene id: 290512:PAES_RS09175
uniprot id: B4S459
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

290512:PAES RS09370
gene id: 290512:PAES_RS09370
uniprot id: B4S4J4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

290512:PAES RS07415
gene id: 290512:PAES_RS07415
uniprot id: B4S8W6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

290512:PAES RS01375
gene id: 290512:PAES_RS01375
uniprot id: B4S486
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

290512:PAES RS03965
gene id: 290512:PAES_RS03965
uniprot id: B4S704
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

290512:PAES RS11275
gene id: 290512:PAES_RS11275
uniprot id: B4S6R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

290512:PAES RS09385
gene id: 290512:PAES_RS09385
uniprot id: B4S4J7
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

290512:PAES RS00130
gene id: 290512:PAES_RS00130
uniprot id: B4S960
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

290512:PAES RS04535
gene id: 290512:PAES_RS04535
uniprot id: B4S7A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

290512:PAES RS06785
gene id: 290512:PAES_RS06785
uniprot id: B4S8J0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS09440
gene id: 290512:PAES_RS09440
uniprot id: B4S4K7
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

290512:PAES RS11195
gene id: 290512:PAES_RS11195
uniprot id: B4S6E9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

290512:PAES RS03455
gene id: 290512:PAES_RS03455
uniprot id: B4S6I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

290512:PAES RS00960
gene id: 290512:PAES_RS00960
uniprot id: B4S3Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

290512:PAES RS00800
gene id: 290512:PAES_RS00800
uniprot id: B4S3C4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS00825
gene id: 290512:PAES_RS00825
uniprot id: B4S3C9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

290512:PAES RS06355
gene id: 290512:PAES_RS06355
uniprot id: B4S8A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

290512:PAES RS10065
gene id: 290512:PAES_RS10065
uniprot id: B4S582
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

290512:PAES RS03560
gene id: 290512:PAES_RS03560
uniprot id: B4S6K3
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

290512:PAES RS10225
gene id: 290512:PAES_RS10225
uniprot id: B4S5B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

290512:PAES RS01860
gene id: 290512:PAES_RS01860
uniprot id: B4S4S9
names: Similarity
messages: Belongs to the ribF family.

290512:PAES RS04300
gene id: 290512:PAES_RS04300
uniprot id: B4S764
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

290512:PAES RS04380
gene id: 290512:PAES_RS04380
uniprot id: B4S780
names: Similarity
messages: Belongs to the band 7/mec-2 family.

290512:PAES RS10255
gene id: 290512:PAES_RS10255
uniprot id: B4S5C0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

290512:PAES RS08910
gene id: 290512:PAES_RS08910
uniprot id: B4S406
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

290512:PAES RS04610
gene id: 290512:PAES_RS04610
uniprot id: B4S7C0
names: Similarity
messages: Belongs to the universal stress protein A family.

290512:PAES RS07850
gene id: 290512:PAES_RS07850
uniprot id: B4S9B9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

290512:PAES RS06770
gene id: 290512:PAES_RS06770
uniprot id: B4S8I7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

290512:PAES RS09045
gene id: 290512:PAES_RS09045
uniprot id: B4S432
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

290512:PAES RS00105
gene id: 290512:PAES_RS00105
uniprot id: B4S955
names: Similarity
messages: Belongs to the peptidase S41A family.

290512:PAES RS01960
gene id: 290512:PAES_RS01960
uniprot id: B4S4U9
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

290512:PAES RS06570
gene id: 290512:PAES_RS06570
uniprot id: B4S8E9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

290512:PAES RS08545
gene id: 290512:PAES_RS08545
uniprot id: B4S3I8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

290512:PAES RS06060
gene id: 290512:PAES_RS06060
uniprot id: B4S852
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS01850
gene id: 290512:PAES_RS01850
uniprot id: B4S4S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

290512:PAES RS11330
gene id: 290512:PAES_RS11330
uniprot id: B4S6S3
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS00460
gene id: 290512:PAES_RS00460
uniprot id: B4S362
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS01225
gene id: 290512:PAES_RS01225
uniprot id: B4S3V7
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

290512:PAES RS10335
gene id: 290512:PAES_RS10335
uniprot id: B4S5N6
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS07495
gene id: 290512:PAES_RS07495
uniprot id: B4S8Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

290512:PAES RS04165
gene id: 290512:PAES_RS04165
uniprot id: B4S739
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

290512:PAES RS02420
gene id: 290512:PAES_RS02420
uniprot id: B4S5E4
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

290512:PAES RS07295
gene id: 290512:PAES_RS07295
uniprot id: B4S8U4
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

290512:PAES RS03540
gene id: 290512:PAES_RS03540
uniprot id: B4S6J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

290512:PAES RS10360
gene id: 290512:PAES_RS10360
uniprot id: B4S5P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

290512:PAES RS10960
gene id: 290512:PAES_RS10960
uniprot id: B4S6A3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

290512:PAES RS01700
gene id: 290512:PAES_RS01700
uniprot id: B4S4E7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

290512:PAES RS05265
gene id: 290512:PAES_RS05265
uniprot id: B4S7P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

290512:PAES RS08740
gene id: 290512:PAES_RS08740
uniprot id: B4S3M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

290512:PAES RS03815
gene id: 290512:PAES_RS03815
uniprot id: B4S6Q3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

290512:PAES RS00600
gene id: 290512:PAES_RS00600
uniprot id: B4S389
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

290512:PAES RS02660
gene id: 290512:PAES_RS02660
uniprot id: B4S5J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

290512:PAES RS05155
gene id: 290512:PAES_RS05155
uniprot id: B4S7M8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

290512:PAES RS03445
gene id: 290512:PAES_RS03445
uniprot id: B4S6I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

290512:PAES RS01155
gene id: 290512:PAES_RS01155
uniprot id: B4S3U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BChl C/E-binding protein family.
messages: Component of the photosynthetic apparatus.
messages: chlorosome envelope

290512:PAES RS08900
gene id: 290512:PAES_RS08900
uniprot id: B4S404
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

290512:PAES RS02680
gene id: 290512:PAES_RS02680
uniprot id: B4S5J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

290512:PAES RS04160
gene id: 290512:PAES_RS04160
uniprot id: B4S738
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS01955
gene id: 290512:PAES_RS01955
uniprot id: B4S4U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

290512:PAES RS05010
gene id: 290512:PAES_RS05010
uniprot id: B4S7J9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

290512:PAES RS11260
gene id: 290512:PAES_RS11260
uniprot id: B4S6Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

290512:PAES RS08635
gene id: 290512:PAES_RS08635
uniprot id: B4S3K6
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

290512:PAES RS11625
gene id: 290512:PAES_RS11625
uniprot id: B4S9K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

290512:PAES RS04245
gene id: 290512:PAES_RS04245
uniprot id: B4S753
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

290512:PAES RS08175
gene id: 290512:PAES_RS08175
uniprot id: B4S9I4
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

290512:PAES RS02620
gene id: 290512:PAES_RS02620
uniprot id: B4S5I3
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

290512:PAES RS07915
gene id: 290512:PAES_RS07915
uniprot id: B4S9D2
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

290512:PAES RS03785
gene id: 290512:PAES_RS03785
uniprot id: B4S6P7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

290512:PAES RS02770
gene id: 290512:PAES_RS02770
uniprot id: B4S5L6
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

290512:PAES RS07680
gene id: 290512:PAES_RS07680
uniprot id: B4S919
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

290512:PAES RS06090
gene id: 290512:PAES_RS06090
uniprot id: B4S858
names: Subcellular Location Annotation
messages: chloroplast

290512:PAES RS05980
gene id: 290512:PAES_RS05980
uniprot id: B4S837
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

290512:PAES RS11805
gene id: 290512:PAES_RS11805
uniprot id: B4S9P2
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

290512:PAES RS09690
gene id: 290512:PAES_RS09690
uniprot id: B4S4Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

290512:PAES RS11235
gene id: 290512:PAES_RS11235
uniprot id: B4S6F7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS04275
gene id: 290512:PAES_RS04275
uniprot id: B4S759
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS00470
gene id: 290512:PAES_RS00470
uniprot id: B4S364
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

290512:PAES RS09505
gene id: 290512:PAES_RS09505
uniprot id: B4S4M0
names: Similarity
messages: Belongs to the transketolase family.

290512:PAES RS01905
gene id: 290512:PAES_RS01905
uniprot id: B4S4T8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

290512:PAES RS06135
gene id: 290512:PAES_RS06135
uniprot id: B4S866
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

290512:PAES RS07845
gene id: 290512:PAES_RS07845
uniprot id: B4S9B8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

290512:PAES RS09315
gene id: 290512:PAES_RS09315
uniprot id: B4S4I3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

290512:PAES RS08450
gene id: 290512:PAES_RS08450
uniprot id: B4S3H0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

290512:PAES RS09630
gene id: 290512:PAES_RS09630
uniprot id: B4S4P5
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

290512:PAES RS09695
gene id: 290512:PAES_RS09695
uniprot id: B4S4Q9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

290512:PAES RS11165
gene id: 290512:PAES_RS11165
uniprot id: B4S6E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains (By similarity).

290512:PAES RS05280
gene id: 290512:PAES_RS05280
uniprot id: B4S7Q2
names: Similarity
messages: Belongs to the universal stress protein A family.

290512:PAES RS09325
gene id: 290512:PAES_RS09325
uniprot id: B4S4I5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

290512:PAES RS08805
gene id: 290512:PAES_RS08805
uniprot id: B4S3Y5
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS04540
gene id: 290512:PAES_RS04540
uniprot id: B4S7A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

290512:PAES RS01345
gene id: 290512:PAES_RS01345
uniprot id: B4S480
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

290512:PAES RS02475
gene id: 290512:PAES_RS02475
uniprot id: B4S5F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

290512:PAES RS08155
gene id: 290512:PAES_RS08155
uniprot id: B4S9I0
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

290512:PAES RS11120
gene id: 290512:PAES_RS11120
uniprot id: B4S6D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

290512:PAES RS09020
gene id: 290512:PAES_RS09020
uniprot id: B4S427
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

290512:PAES RS04490
gene id: 290512:PAES_RS04490
uniprot id: B4S798
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a, b, b' and c.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

290512:PAES RS02100
gene id: 290512:PAES_RS02100
uniprot id: B4S4X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

290512:PAES RS05385
gene id: 290512:PAES_RS05385
uniprot id: B4S7R9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

290512:PAES RS01425
gene id: 290512:PAES_RS01425
uniprot id: B4S492
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

290512:PAES RS04495
gene id: 290512:PAES_RS04495
uniprot id: B4S799
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(1), b'(1) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta, b and b' chains.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

290512:PAES RS10425
gene id: 290512:PAES_RS10425
uniprot id: B4S5Q4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

290512:PAES RS00840
gene id: 290512:PAES_RS00840
uniprot id: B4S3D2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

290512:PAES RS05905
gene id: 290512:PAES_RS05905
uniprot id: B4S821
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

290512:PAES RS02755
gene id: 290512:PAES_RS02755
uniprot id: B4S5L3
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

290512:PAES RS05900
gene id: 290512:PAES_RS05900
uniprot id: B4S820
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

290512:PAES RS08445
gene id: 290512:PAES_RS08445
uniprot id: B4S3G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

290512:PAES RS10585
gene id: 290512:PAES_RS10585
uniprot id: B4S5T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

290512:PAES RS02750
gene id: 290512:PAES_RS02750
uniprot id: B4S5L2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

290512:PAES RS05700
gene id: 290512:PAES_RS05700
uniprot id: B4S7X8
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS10760
gene id: 290512:PAES_RS10760
uniprot id: B4S5W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

290512:PAES RS00165
gene id: 290512:PAES_RS00165
uniprot id: B4S967
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

290512:PAES RS03535
gene id: 290512:PAES_RS03535
uniprot id: B4S6J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

290512:PAES RS10315
gene id: 290512:PAES_RS10315
uniprot id: B4S5N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

290512:PAES RS05235
gene id: 290512:PAES_RS05235
uniprot id: B4S7P3
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

290512:PAES RS01455
gene id: 290512:PAES_RS01455
uniprot id: B4S498
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

290512:PAES RS05545
gene id: 290512:PAES_RS05545
uniprot id: B4S7V2
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS08695
gene id: 290512:PAES_RS08695
uniprot id: B4S3L9
names: Similarity
messages: Belongs to the universal stress protein A family.

290512:PAES RS02350
gene id: 290512:PAES_RS02350
uniprot id: B4S5D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

290512:PAES RS01865
gene id: 290512:PAES_RS01865
uniprot id: B4S4T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

290512:PAES RS07825
gene id: 290512:PAES_RS07825
uniprot id: B4S9B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

290512:PAES RS04235
gene id: 290512:PAES_RS04235
uniprot id: B4S751
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

290512:PAES RS10640
gene id: 290512:PAES_RS10640
uniprot id: B4S5U3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
messages: The residue potentially involved in the covalent binding of FMN is a Ser instead of a Thr.

290512:PAES RS06625
gene id: 290512:PAES_RS06625
uniprot id: B4S8G1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

290512:PAES RS06580
gene id: 290512:PAES_RS06580
uniprot id: B4S8F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

290512:PAES RS02975
gene id: 290512:PAES_RS02975
uniprot id: B4S602
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

290512:PAES RS07840
gene id: 290512:PAES_RS07840
uniprot id: B4S9B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

290512:PAES RS04150
gene id: 290512:PAES_RS04150
uniprot id: B4S736
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

290512:PAES RS09750
gene id: 290512:PAES_RS09750
uniprot id: B4S4S0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

290512:PAES RS10880
gene id: 290512:PAES_RS10880
uniprot id: B4S686
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS02395
gene id: 290512:PAES_RS02395
uniprot id: B4S5D9
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS06405
gene id: 290512:PAES_RS06405
uniprot id: B4S8B5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

290512:PAES RS07905
gene id: 290512:PAES_RS07905
uniprot id: B4S9D0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

290512:PAES RS02845
gene id: 290512:PAES_RS02845
uniprot id: B4S5X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

290512:PAES RS02790
gene id: 290512:PAES_RS02790
uniprot id: B4S5M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

290512:PAES RS04650
gene id: 290512:PAES_RS04650
uniprot id: B4S7C8
names: Similarity
messages: Belongs to the thioredoxin family.

290512:PAES RS07920
gene id: 290512:PAES_RS07920
uniprot id: B4S9D3
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

290512:PAES RS08875
gene id: 290512:PAES_RS08875
uniprot id: B4S400
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS05000
gene id: 290512:PAES_RS05000
uniprot id: B4S7J7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS02935
gene id: 290512:PAES_RS02935
uniprot id: B4S5Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

290512:PAES RS11820
gene id: 290512:PAES_RS11820
uniprot id: B4S9P5
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

290512:PAES RS09865
gene id: 290512:PAES_RS09865
uniprot id: B4S543
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

290512:PAES RS09270
gene id: 290512:PAES_RS09270
uniprot id: B4S4H4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

290512:PAES RS02465
gene id: 290512:PAES_RS02465
uniprot id: B4S5F3
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

290512:PAES RS06590
gene id: 290512:PAES_RS06590
uniprot id: B4S8F3
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS09725
gene id: 290512:PAES_RS09725
uniprot id: B4S4R5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS05840
gene id: 290512:PAES_RS05840
uniprot id: B4S808
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

290512:PAES RS06825
gene id: 290512:PAES_RS06825
uniprot id: B4S8J7
names: Similarity
messages: Belongs to the CFA/CMAS family.

290512:PAES RS08905
gene id: 290512:PAES_RS08905
uniprot id: B4S405
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

290512:PAES RS05770
gene id: 290512:PAES_RS05770
uniprot id: B4S7Z4
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS11595
gene id: 290512:PAES_RS11595
uniprot id: B4S6X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

290512:PAES RS11270
gene id: 290512:PAES_RS11270
uniprot id: B4S6R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

290512:PAES RS00860
gene id: 290512:PAES_RS00860
uniprot id: B4S3N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

290512:PAES RS02840
gene id: 290512:PAES_RS02840
uniprot id: B4S5X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

290512:PAES RS03645
gene id: 290512:PAES_RS03645
uniprot id: B4S6L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

290512:PAES RS02115
gene id: 290512:PAES_RS02115
uniprot id: B4S4X8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

290512:PAES RS00670
gene id: 290512:PAES_RS00670
uniprot id: B4S3A3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

290512:PAES RS05110
gene id: 290512:PAES_RS05110
uniprot id: B4S7L9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

290512:PAES RS09160
gene id: 290512:PAES_RS09160
uniprot id: B4S456
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

290512:PAES RS03675
gene id: 290512:PAES_RS03675
uniprot id: B4S6M5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

290512:PAES RS00775
gene id: 290512:PAES_RS00775
uniprot id: B4S3B9
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

290512:PAES RS00575
gene id: 290512:PAES_RS00575
uniprot id: B4S385
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

290512:PAES RS05925
gene id: 290512:PAES_RS05925
uniprot id: B4S825
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS08330
gene id: 290512:PAES_RS08330
uniprot id: B4S3E6
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

290512:PAES RS00135
gene id: 290512:PAES_RS00135
uniprot id: B4S961
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

290512:PAES RS10135
gene id: 290512:PAES_RS10135
uniprot id: B4S596
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

290512:PAES RS05125
gene id: 290512:PAES_RS05125
uniprot id: B4S7M2
names: Similarity
messages: Belongs to the Nth/MutY family.

290512:PAES RS05005
gene id: 290512:PAES_RS05005
uniprot id: B4S7J8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

290512:PAES RS00975
gene id: 290512:PAES_RS00975
uniprot id: B4S3Q7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

290512:PAES RS02535
gene id: 290512:PAES_RS02535
uniprot id: B4S5G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

290512:PAES RS08090
gene id: 290512:PAES_RS08090
uniprot id: B4S9G7
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS04595
gene id: 290512:PAES_RS04595
uniprot id: B4S7B8
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS08055
gene id: 290512:PAES_RS08055
uniprot id: B4S9G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

290512:PAES RS10040
gene id: 290512:PAES_RS10040
uniprot id: B4S577
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

290512:PAES RS10885
gene id: 290512:PAES_RS10885
uniprot id: B4S687
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

290512:PAES RS07305
gene id: 290512:PAES_RS07305
uniprot id: B4S8U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

290512:PAES RS01355
gene id: 290512:PAES_RS01355
uniprot id: B4S482
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS12170
gene id: 290512:PAES_RS12170
uniprot id: B4S9L9
names: Similarity
messages: Belongs to the TrbI/VirB10 family.

290512:PAES RS07175
gene id: 290512:PAES_RS07175
uniprot id: B4S8R9
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

290512:PAES RS06560
gene id: 290512:PAES_RS06560
uniprot id: B4S8E7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

290512:PAES RS05105
gene id: 290512:PAES_RS05105
uniprot id: B4S7L8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

290512:PAES RS08685
gene id: 290512:PAES_RS08685
uniprot id: B4S3L7
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

290512:PAES RS07365
gene id: 290512:PAES_RS07365
uniprot id: B4S8V6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

290512:PAES RS02700
gene id: 290512:PAES_RS02700
uniprot id: B4S5K2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

290512:PAES RS08535
gene id: 290512:PAES_RS08535
uniprot id: B4S3I6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

290512:PAES RS03025
gene id: 290512:PAES_RS03025
uniprot id: B4S612
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

290512:PAES RS07290
gene id: 290512:PAES_RS07290
uniprot id: B4S8U3
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

290512:PAES RS05725
gene id: 290512:PAES_RS05725
uniprot id: B4S7Y5
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS08215
gene id: 290512:PAES_RS08215
uniprot id: B4S9J2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

290512:PAES RS03605
gene id: 290512:PAES_RS03605
uniprot id: B4S6L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

290512:PAES RS02410
gene id: 290512:PAES_RS02410
uniprot id: B4S5E2
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS08125
gene id: 290512:PAES_RS08125
uniprot id: B4S9H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

290512:PAES RS02570
gene id: 290512:PAES_RS02570
uniprot id: B4S5H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

290512:PAES RS04270
gene id: 290512:PAES_RS04270
uniprot id: B4S758
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

290512:PAES RS08425
gene id: 290512:PAES_RS08425
uniprot id: B4S3G5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

290512:PAES RS01920
gene id: 290512:PAES_RS01920
uniprot id: B4S4U1
names: Similarity
messages: Belongs to the DprA/Smf family.

290512:PAES RS00060
gene id: 290512:PAES_RS00060
uniprot id: B4S946
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

290512:PAES RS05945
gene id: 290512:PAES_RS05945
uniprot id: B4S830
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

290512:PAES RS10110
gene id: 290512:PAES_RS10110
uniprot id: B4S591
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
messages: Homodimer. Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB.

290512:PAES RS10310
gene id: 290512:PAES_RS10310
uniprot id: B4S5N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

290512:PAES RS07150
gene id: 290512:PAES_RS07150
uniprot id: B4S8R6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

290512:PAES RS01820
gene id: 290512:PAES_RS01820
uniprot id: B4S4H1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

290512:PAES RS08150
gene id: 290512:PAES_RS08150
uniprot id: B4S9H9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

290512:PAES RS02730
gene id: 290512:PAES_RS02730
uniprot id: B4S5K8
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

290512:PAES RS08335
gene id: 290512:PAES_RS08335
uniprot id: B4S3E7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

290512:PAES RS10220
gene id: 290512:PAES_RS10220
uniprot id: B4S5B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

290512:PAES RS04325
gene id: 290512:PAES_RS04325
uniprot id: B4S769
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

290512:PAES RS00540
gene id: 290512:PAES_RS00540
uniprot id: B4S378
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

290512:PAES RS00280
gene id: 290512:PAES_RS00280
uniprot id: B4S989
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

290512:PAES RS12040
gene id: 290512:PAES_RS12040
uniprot id: B4S7Z0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

290512:PAES RS00790
gene id: 290512:PAES_RS00790
uniprot id: B4S3C2
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

290512:PAES RS08500
gene id: 290512:PAES_RS08500
uniprot id: B4S3I0
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS07500
gene id: 290512:PAES_RS07500
uniprot id: B4S8Y3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

290512:PAES RS12450
gene id: 290512:PAES_RS12450
uniprot id: B4S5A5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

290512:PAES RS08285
gene id: 290512:PAES_RS08285
uniprot id: B4S3D7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

290512:PAES RS02200
gene id: 290512:PAES_RS02200
uniprot id: B4S4Z6
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

290512:PAES RS00615
gene id: 290512:PAES_RS00615
uniprot id: B4S392
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

290512:PAES RS08180
gene id: 290512:PAES_RS08180
uniprot id: B4S9I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

290512:PAES RS05435
gene id: 290512:PAES_RS05435
uniprot id: B4S7S9
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

290512:PAES RS08130
gene id: 290512:PAES_RS08130
uniprot id: B4S9H5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

290512:PAES RS09585
gene id: 290512:PAES_RS09585
uniprot id: B4S4N6
names: Similarity
messages: Belongs to the peptidase S16 family.

290512:PAES RS11590
gene id: 290512:PAES_RS11590
uniprot id: B4S6X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

290512:PAES RS09770
gene id: 290512:PAES_RS09770
uniprot id: B4S524
names: Similarity
messages: Belongs to the arsA ATPase family.

290512:PAES RS02710
gene id: 290512:PAES_RS02710
uniprot id: B4S5K4
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS09760
gene id: 290512:PAES_RS09760
uniprot id: B4S4S2
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

290512:PAES RS06740
gene id: 290512:PAES_RS06740
uniprot id: B4S8I1
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS11130
gene id: 290512:PAES_RS11130
uniprot id: B4S6D8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

290512:PAES RS10945
gene id: 290512:PAES_RS10945
uniprot id: B4S6A0
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

290512:PAES RS02610
gene id: 290512:PAES_RS02610
uniprot id: B4S5I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

290512:PAES RS00240
gene id: 290512:PAES_RS00240
uniprot id: B4S982
names: Similarity
messages: Belongs to the peptidase S66 family.

290512:PAES RS08950
gene id: 290512:PAES_RS08950
uniprot id: B4S414
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

290512:PAES RS03760
gene id: 290512:PAES_RS03760
uniprot id: B4S6P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TolB family.
messages: Periplasm

290512:PAES RS08220
gene id: 290512:PAES_RS08220
uniprot id: B4S9J3
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

290512:PAES RS02555
gene id: 290512:PAES_RS02555
uniprot id: B4S5H1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

290512:PAES RS11415
gene id: 290512:PAES_RS11415
uniprot id: B4S6T9
names: Similarity
messages: Belongs to the Fur family.

290512:PAES RS07355
gene id: 290512:PAES_RS07355
uniprot id: B4S8V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell inner membrane

290512:PAES RS02655
gene id: 290512:PAES_RS02655
uniprot id: B4S5J3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

290512:PAES RS07015
gene id: 290512:PAES_RS07015
uniprot id: B4S8N4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

290512:PAES RS01470
gene id: 290512:PAES_RS01470
uniprot id: B4S4A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

290512:PAES RS00580
gene id: 290512:PAES_RS00580
uniprot id: B4S386
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

290512:PAES RS01695
gene id: 290512:PAES_RS01695
uniprot id: B4S4E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

290512:PAES RS05410
gene id: 290512:PAES_RS05410
uniprot id: B4S7S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

290512:PAES RS02830
gene id: 290512:PAES_RS02830
uniprot id: B4S5X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

290512:PAES RS07860
gene id: 290512:PAES_RS07860
uniprot id: B4S9C1
names: Similarity
messages: Belongs to the Fur family.

290512:PAES RS08915
gene id: 290512:PAES_RS08915
uniprot id: B4S407
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

290512:PAES RS05970
gene id: 290512:PAES_RS05970
uniprot id: B4S835
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

290512:PAES RS00290
gene id: 290512:PAES_RS00290
uniprot id: B4S991
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

290512:PAES RS11320
gene id: 290512:PAES_RS11320
uniprot id: B4S6S1
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

290512:PAES RS01295
gene id: 290512:PAES_RS01295
uniprot id: B4S3X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a, b, b' and c.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

290512:PAES RS09190
gene id: 290512:PAES_RS09190
uniprot id: B4S462
names: Similarity
messages: Belongs to the BshC family.

290512:PAES RS09305
gene id: 290512:PAES_RS09305
uniprot id: B4S4I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

290512:PAES RS02090
gene id: 290512:PAES_RS02090
uniprot id: B4S4X3
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

290512:PAES RS04265
gene id: 290512:PAES_RS04265
uniprot id: B4S757
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

290512:PAES RS02745
gene id: 290512:PAES_RS02745
uniprot id: B4S5L1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

290512:PAES RS02980
gene id: 290512:PAES_RS02980
uniprot id: B4S603
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

290512:PAES RS00845
gene id: 290512:PAES_RS00845
uniprot id: B4S3D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Chlorophyllide reductase is composed of three subunits; BchX, BchY and BchZ. Forms a heterodimer of one BchY and one BchZ subunit.
messages: Converts chlorophylls (Chl) into bacteriochlorophylls (BChl) by reducing ring B of the tetrapyrrole.

290512:PAES RS07180
gene id: 290512:PAES_RS07180
uniprot id: B4S8S0
names: Function
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.
messages: Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.

290512:PAES RS01635
gene id: 290512:PAES_RS01635
uniprot id: B4S4D5
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

290512:PAES RS08195
gene id: 290512:PAES_RS08195
uniprot id: B4S9I8
names: Similarity
messages: Belongs to the HypE family.

290512:PAES RS09290
gene id: 290512:PAES_RS09290
uniprot id: B4S4H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

290512:PAES RS10185
gene id: 290512:PAES_RS10185
uniprot id: B4S5A7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

290512:PAES RS01300
gene id: 290512:PAES_RS01300
uniprot id: B4S3X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

290512:PAES RS00850
gene id: 290512:PAES_RS00850
uniprot id: B4S3N2
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

290512:PAES RS07605
gene id: 290512:PAES_RS07605
uniprot id: B4S904
names: Similarity
messages: Belongs to the glutamine synthetase family.

290512:PAES RS11170
gene id: 290512:PAES_RS11170
uniprot id: B4S6E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(1), b'(1) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta, b and b' chains.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

290512:PAES RS06295
gene id: 290512:PAES_RS06295
uniprot id: B4S894
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

290512:PAES RS02965
gene id: 290512:PAES_RS02965
uniprot id: B4S600
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

290512:PAES RS07425
gene id: 290512:PAES_RS07425
uniprot id: B4S8W8
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS10035
gene id: 290512:PAES_RS10035
uniprot id: B4S576
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

290512:PAES RS05450
gene id: 290512:PAES_RS05450
uniprot id: B4S7T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

290512:PAES RS04250
gene id: 290512:PAES_RS04250
uniprot id: B4S754
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).

290512:PAES RS00170
gene id: 290512:PAES_RS00170
uniprot id: B4S968
names: Similarity
messages: Belongs to the DsrF/TusC family.

290512:PAES RS07465
gene id: 290512:PAES_RS07465
uniprot id: B4S8X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

290512:PAES RS12095
gene id: 290512:PAES_RS12095
uniprot id: B4S3J0
names: Similarity
messages: Belongs to the TrbI/VirB10 family.

290512:PAES RS02490
gene id: 290512:PAES_RS02490
uniprot id: B4S5F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

290512:PAES RS08390
gene id: 290512:PAES_RS08390
uniprot id: B4S3F8
names: Similarity
messages: Belongs to the arsA ATPase family.

290512:PAES RS10610
gene id: 290512:PAES_RS10610
uniprot id: B4S5T7
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

290512:PAES RS08310
gene id: 290512:PAES_RS08310
uniprot id: B4S3E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

290512:PAES RS04435
gene id: 290512:PAES_RS04435
uniprot id: B4S790
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

290512:PAES RS02260
gene id: 290512:PAES_RS02260
uniprot id: B4S510
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

290512:PAES RS02440
gene id: 290512:PAES_RS02440
uniprot id: B4S5E8
names: Similarity
messages: Belongs to the CarB family.

290512:PAES RS03665
gene id: 290512:PAES_RS03665
uniprot id: B4S6M3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

290512:PAES RS05095
gene id: 290512:PAES_RS05095
uniprot id: B4S7L6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

290512:PAES RS04510
gene id: 290512:PAES_RS04510
uniprot id: B4S7A2
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

290512:PAES RS08405
gene id: 290512:PAES_RS08405
uniprot id: B4S3G1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

290512:PAES RS06610
gene id: 290512:PAES_RS06610
uniprot id: B4S8F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell inner membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

290512:PAES RS10290
gene id: 290512:PAES_RS10290
uniprot id: B4S5M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

290512:PAES RS06520
gene id: 290512:PAES_RS06520
uniprot id: B4S8D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

290512:PAES RS04135
gene id: 290512:PAES_RS04135
uniprot id: B4S733
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS08365
gene id: 290512:PAES_RS08365
uniprot id: B4S3F3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

290512:PAES RS00085
gene id: 290512:PAES_RS00085
uniprot id: B4S951
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

290512:PAES RS04310
gene id: 290512:PAES_RS04310
uniprot id: B4S766
names: Similarity
messages: Belongs to the peptidase A31 family.

290512:PAES RS01350
gene id: 290512:PAES_RS01350
uniprot id: B4S481
names: Similarity
messages: Belongs to the MEMO1 family.

290512:PAES RS03450
gene id: 290512:PAES_RS03450
uniprot id: B4S6I5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

290512:PAES RS03495
gene id: 290512:PAES_RS03495
uniprot id: B4S6J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

290512:PAES RS10245
gene id: 290512:PAES_RS10245
uniprot id: B4S5B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

290512:PAES RS00265
gene id: 290512:PAES_RS00265
uniprot id: B4S986
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

290512:PAES RS10555
gene id: 290512:PAES_RS10555
uniprot id: B4S5S6
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS04155
gene id: 290512:PAES_RS04155
uniprot id: B4S737
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

290512:PAES RS02520
gene id: 290512:PAES_RS02520
uniprot id: B4S5G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

290512:PAES RS10825
gene id: 290512:PAES_RS10825
uniprot id: B4S675
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

290512:PAES RS05610
gene id: 290512:PAES_RS05610
uniprot id: B4S7W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

290512:PAES RS02515
gene id: 290512:PAES_RS02515
uniprot id: B4S5G3
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS02220
gene id: 290512:PAES_RS02220
uniprot id: B4S500
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

290512:PAES RS11325
gene id: 290512:PAES_RS11325
uniprot id: B4S6S2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

290512:PAES RS07055
gene id: 290512:PAES_RS07055
uniprot id: B4S8P2
names: Similarity
messages: Belongs to the ferrochelatase family.

290512:PAES RS00465
gene id: 290512:PAES_RS00465
uniprot id: B4S363
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS03530
gene id: 290512:PAES_RS03530
uniprot id: B4S6J7
names: Cofactor
names: Similarity
messages: Belongs to the PdaD family.
messages: Binds 1 pyruvoyl group covalently per subunit.

290512:PAES RS10020
gene id: 290512:PAES_RS10020
uniprot id: B4S573
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

290512:PAES RS09520
gene id: 290512:PAES_RS09520
uniprot id: B4S4M3
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

290512:PAES RS09500
gene id: 290512:PAES_RS09500
uniprot id: B4S4L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

290512:PAES RS00515
gene id: 290512:PAES_RS00515
uniprot id: B4S373
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS09640
gene id: 290512:PAES_RS09640
uniprot id: B4S4P7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

290512:PAES RS02705
gene id: 290512:PAES_RS02705
uniprot id: B4S5K3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

290512:PAES RS06080
gene id: 290512:PAES_RS06080
uniprot id: B4S856
names: Similarity
messages: Belongs to the DNA photolyase family.

290512:PAES RS04500
gene id: 290512:PAES_RS04500
uniprot id: B4S7A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains (By similarity).

290512:PAES RS04955
gene id: 290512:PAES_RS04955
uniprot id: B4S7I8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane

290512:PAES RS07895
gene id: 290512:PAES_RS07895
uniprot id: B4S9C8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

290512:PAES RS03390
gene id: 290512:PAES_RS03390
uniprot id: B4S6H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

290512:PAES RS10635
gene id: 290512:PAES_RS10635
uniprot id: B4S5U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

290512:PAES RS03955
gene id: 290512:PAES_RS03955
uniprot id: B4S702
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

290512:PAES RS00865
gene id: 290512:PAES_RS00865
uniprot id: B4S3N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

290512:PAES RS00820
gene id: 290512:PAES_RS00820
uniprot id: B4S3C8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

290512:PAES RS11200
gene id: 290512:PAES_RS11200
uniprot id: B4S6F0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

290512:PAES RS01080
gene id: 290512:PAES_RS01080
uniprot id: B4S3S7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

290512:PAES RS09140
gene id: 290512:PAES_RS09140
uniprot id: B4S452
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

290512:PAES RS04120
gene id: 290512:PAES_RS04120
uniprot id: B4S731
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

290512:PAES RS02955
gene id: 290512:PAES_RS02955
uniprot id: B4S5Z8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

290512:PAES RS00630
gene id: 290512:PAES_RS00630
uniprot id: B4S395
names: Similarity
messages: Belongs to the P(II) protein family.

290512:PAES RS00075
gene id: 290512:PAES_RS00075
uniprot id: B4S949
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

290512:PAES RS04635
gene id: 290512:PAES_RS04635
uniprot id: B4S7C5
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

290512:PAES RS08000
gene id: 290512:PAES_RS08000
uniprot id: B4S9E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

290512:PAES RS08375
gene id: 290512:PAES_RS08375
uniprot id: B4S3F5
names: Similarity
messages: Belongs to the pirin family.

290512:PAES RS03790
gene id: 290512:PAES_RS03790
uniprot id: B4S6P8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

290512:PAES RS00185
gene id: 290512:PAES_RS00185
uniprot id: B4S971
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS00680
gene id: 290512:PAES_RS00680
uniprot id: B4S3A5
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

290512:PAES RS00100
gene id: 290512:PAES_RS00100
uniprot id: B4S954
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

290512:PAES RS10365
gene id: 290512:PAES_RS10365
uniprot id: B4S5P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

290512:PAES RS09025
gene id: 290512:PAES_RS09025
uniprot id: B4S428
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS07645
gene id: 290512:PAES_RS07645
uniprot id: B4S912
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

290512:PAES RS08775
gene id: 290512:PAES_RS08775
uniprot id: B4S3Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

290512:PAES RS03655
gene id: 290512:PAES_RS03655
uniprot id: B4S6M1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

290512:PAES RS02030
gene id: 290512:PAES_RS02030
uniprot id: B4S4W1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

290512:PAES RS04420
gene id: 290512:PAES_RS04420
uniprot id: B4S787
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

290512:PAES RS03975
gene id: 290512:PAES_RS03975
uniprot id: B4S706
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

290512:PAES RS07775
gene id: 290512:PAES_RS07775
uniprot id: B4S9A4
names: Similarity
messages: Belongs to the DEAD box helicase family.

290512:PAES RS02390
gene id: 290512:PAES_RS02390
uniprot id: B4S5D8
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

290512:PAES RS01255
gene id: 290512:PAES_RS01255
uniprot id: B4S3W4
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS06975
gene id: 290512:PAES_RS06975
uniprot id: B4S8M6
names: Similarity
messages: Belongs to the LOG family.

290512:PAES RS09745
gene id: 290512:PAES_RS09745
uniprot id: B4S4R9
names: Similarity
messages: Belongs to the peptidase M16 family.

290512:PAES RS09320
gene id: 290512:PAES_RS09320
uniprot id: B4S4I4
names: Similarity
messages: Belongs to the UPF0235 family.

290512:PAES RS00920
gene id: 290512:PAES_RS00920
uniprot id: B4S3P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

290512:PAES RS02170
gene id: 290512:PAES_RS02170
uniprot id: B4S4Z0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

290512:PAES RS08620
gene id: 290512:PAES_RS08620
uniprot id: B4S3K3
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

290512:PAES RS02545
gene id: 290512:PAES_RS02545
uniprot id: B4S5G9
names: Similarity
messages: Belongs to the peptidase S49 family.

290512:PAES RS04390
gene id: 290512:PAES_RS04390
uniprot id: B4S782
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

290512:PAES RS08855
gene id: 290512:PAES_RS08855
uniprot id: B4S3Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

290512:PAES RS11015
gene id: 290512:PAES_RS11015
uniprot id: B4S6B5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

290512:PAES RS05050
gene id: 290512:PAES_RS05050
uniprot id: B4S7K7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

290512:PAES RS07375
gene id: 290512:PAES_RS07375
uniprot id: B4S8V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

290512:PAES RS02785
gene id: 290512:PAES_RS02785
uniprot id: B4S5L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

290512:PAES RS06575
gene id: 290512:PAES_RS06575
uniprot id: B4S8F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

290512:PAES RS06370
gene id: 290512:PAES_RS06370
uniprot id: B4S8A8
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

290512:PAES RS02920
gene id: 290512:PAES_RS02920
uniprot id: B4S5Z1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

290512:PAES RS05930
gene id: 290512:PAES_RS05930
uniprot id: B4S826
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS04175
gene id: 290512:PAES_RS04175
uniprot id: B4S741
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

290512:PAES RS08420
gene id: 290512:PAES_RS08420
uniprot id: B4S3G4
names: Similarity
messages: Belongs to the UPF0047 family.

290512:PAES RS01465
gene id: 290512:PAES_RS01465
uniprot id: B4S4A0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

290512:PAES RS09795
gene id: 290512:PAES_RS09795
uniprot id: B4S529
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

290512:PAES RS01305
gene id: 290512:PAES_RS01305
uniprot id: B4S3X5
names: Similarity
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

290512:PAES RS08625
gene id: 290512:PAES_RS08625
uniprot id: B4S3K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

290512:PAES RS07585
gene id: 290512:PAES_RS07585
uniprot id: B4S900
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS05475
gene id: 290512:PAES_RS05475
uniprot id: B4S7T7
names: Similarity
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

290512:PAES RS08985
gene id: 290512:PAES_RS08985
uniprot id: B4S420
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

290512:PAES RS09070
gene id: 290512:PAES_RS09070
uniprot id: B4S437
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

290512:PAES RS06565
gene id: 290512:PAES_RS06565
uniprot id: B4S8E8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

290512:PAES RS07815
gene id: 290512:PAES_RS07815
uniprot id: B4S9B2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

290512:PAES RS10835
gene id: 290512:PAES_RS10835
uniprot id: B4S677
names: Similarity
messages: Belongs to the aspartokinase family.

290512:PAES RS10140
gene id: 290512:PAES_RS10140
uniprot id: B4S597
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

290512:PAES RS02665
gene id: 290512:PAES_RS02665
uniprot id: B4S5J5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

290512:PAES RS06420
gene id: 290512:PAES_RS06420
uniprot id: B4S8B8
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

290512:PAES RS08185
gene id: 290512:PAES_RS08185
uniprot id: B4S9I6
names: Similarity
messages: Belongs to the ModE family.

290512:PAES RS08820
gene id: 290512:PAES_RS08820
uniprot id: B4S3Y8
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS04285
gene id: 290512:PAES_RS04285
uniprot id: B4S761
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

290512:PAES RS07950
gene id: 290512:PAES_RS07950
uniprot id: B4S9D9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

290512:PAES RS10180
gene id: 290512:PAES_RS10180
uniprot id: B4S5A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

290512:PAES RS05255
gene id: 290512:PAES_RS05255
uniprot id: B4S7P7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

290512:PAES RS07675
gene id: 290512:PAES_RS07675
uniprot id: B4S918
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

290512:PAES RS07565
gene id: 290512:PAES_RS07565
uniprot id: B4S8Z5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS00455
gene id: 290512:PAES_RS00455
uniprot id: B4S361
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

290512:PAES RS05135
gene id: 290512:PAES_RS05135
uniprot id: B4S7M4
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS03570
gene id: 290512:PAES_RS03570
uniprot id: B4S6K5
names: Similarity
messages: Belongs to the GroES chaperonin family.

290512:PAES RS06210
gene id: 290512:PAES_RS06210
uniprot id: B4S878
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

290512:PAES RS02670
gene id: 290512:PAES_RS02670
uniprot id: B4S5J6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

290512:PAES RS10170
gene id: 290512:PAES_RS10170
uniprot id: B4S5A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

290512:PAES RS11090
gene id: 290512:PAES_RS11090
uniprot id: B4S6D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

290512:PAES RS09790
gene id: 290512:PAES_RS09790
uniprot id: B4S528
names: Similarity
messages: Belongs to the arsA ATPase family.

290512:PAES RS03460
gene id: 290512:PAES_RS03460
uniprot id: B4S6I7
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

290512:PAES RS06715
gene id: 290512:PAES_RS06715
uniprot id: B4S8H6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

290512:PAES RS08060
gene id: 290512:PAES_RS08060
uniprot id: B4S9G1
names: Similarity
messages: Belongs to the CIA30 family.

290512:PAES RS04775
gene id: 290512:PAES_RS04775
uniprot id: B4S7F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

290512:PAES RS02450
gene id: 290512:PAES_RS02450
uniprot id: B4S5F0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS08380
gene id: 290512:PAES_RS08380
uniprot id: B4S3F6
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

290512:PAES RS08720
gene id: 290512:PAES_RS08720
uniprot id: B4S3M4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

290512:PAES RS05805
gene id: 290512:PAES_RS05805
uniprot id: B4S801
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

290512:PAES RS00885
gene id: 290512:PAES_RS00885
uniprot id: B4S3N9
names: Similarity
messages: Belongs to the fabD family.

290512:PAES RS03660
gene id: 290512:PAES_RS03660
uniprot id: B4S6M2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

290512:PAES RS02685
gene id: 290512:PAES_RS02685
uniprot id: B4S5J9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

290512:PAES RS07740
gene id: 290512:PAES_RS07740
uniprot id: B4S931
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

290512:PAES RS02530
gene id: 290512:PAES_RS02530
uniprot id: B4S5G6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

290512:PAES RS10195
gene id: 290512:PAES_RS10195
uniprot id: B4S5A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

290512:PAES RS07530
gene id: 290512:PAES_RS07530
uniprot id: B4S8Y8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

290512:PAES RS08990
gene id: 290512:PAES_RS08990
uniprot id: B4S421
names: Similarity
messages: Belongs to the RuBisCO large chain family.

290512:PAES RS06870
gene id: 290512:PAES_RS06870
uniprot id: B4S8K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

290512:PAES RS03705
gene id: 290512:PAES_RS03705
uniprot id: B4S6N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

290512:PAES RS08205
gene id: 290512:PAES_RS08205
uniprot id: B4S9J0
names: Similarity
messages: Belongs to the HupF/HypC family.

290512:PAES RS03525
gene id: 290512:PAES_RS03525
uniprot id: B4S6J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

290512:PAES RS03300
gene id: 290512:PAES_RS03300
uniprot id: B4S662
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

290512:PAES RS07935
gene id: 290512:PAES_RS07935
uniprot id: B4S9D6
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

290512:PAES RS01710
gene id: 290512:PAES_RS01710
uniprot id: B4S4E9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS01925
gene id: 290512:PAES_RS01925
uniprot id: B4S4U2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

290512:PAES RS03145
gene id: 290512:PAES_RS03145
uniprot id: B4S633
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

290512:PAES RS04555
gene id: 290512:PAES_RS04555
uniprot id: B4S7B0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

290512:PAES RS02605
gene id: 290512:PAES_RS02605
uniprot id: B4S5I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

290512:PAES RS05115
gene id: 290512:PAES_RS05115
uniprot id: B4S7M0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

290512:PAES RS06800
gene id: 290512:PAES_RS06800
uniprot id: B4S8J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

290512:PAES RS04580
gene id: 290512:PAES_RS04580
uniprot id: B4S7B5
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

290512:PAES RS05075
gene id: 290512:PAES_RS05075
uniprot id: B4S7L2
names: Similarity
messages: Belongs to the peptidase S41A family.

290512:PAES RS01270
gene id: 290512:PAES_RS01270
uniprot id: B4S3W8
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

290512:PAES RS04140
gene id: 290512:PAES_RS04140
uniprot id: B4S734
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

290512:PAES RS04315
gene id: 290512:PAES_RS04315
uniprot id: B4S767
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

290512:PAES RS08970
gene id: 290512:PAES_RS08970
uniprot id: B4S417
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

290512:PAES RS00025
gene id: 290512:PAES_RS00025
uniprot id: B4S939
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

290512:PAES RS05755
gene id: 290512:PAES_RS05755
uniprot id: B4S7Z1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

290512:PAES RS08080
gene id: 290512:PAES_RS08080
uniprot id: B4S9G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

290512:PAES RS03920
gene id: 290512:PAES_RS03920
uniprot id: B4S6Z5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

290512:PAES RS09055
gene id: 290512:PAES_RS09055
uniprot id: B4S434
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

290512:PAES RS02765
gene id: 290512:PAES_RS02765
uniprot id: B4S5L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

290512:PAES RS02430
gene id: 290512:PAES_RS02430
uniprot id: B4S5E6
names: Similarity
messages: Belongs to the GARS family.

290512:PAES RS10155
gene id: 290512:PAES_RS10155
uniprot id: B4S5A0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

290512:PAES RS08200
gene id: 290512:PAES_RS08200
uniprot id: B4S9I9
names: Similarity
messages: Belongs to the HypD family.

290512:PAES RS00665
gene id: 290512:PAES_RS00665
uniprot id: B4S3A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

290512:PAES RS03385
gene id: 290512:PAES_RS03385
uniprot id: B4S6H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

290512:PAES RS00810
gene id: 290512:PAES_RS00810
uniprot id: B4S3C6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

290512:PAES RS05860
gene id: 290512:PAES_RS05860
uniprot id: B4S812
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS07430
gene id: 290512:PAES_RS07430
uniprot id: B4S8W9
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS00555
gene id: 290512:PAES_RS00555
uniprot id: B4S381
names: Similarity
messages: Belongs to the arsA ATPase family.

290512:PAES RS08455
gene id: 290512:PAES_RS08455
uniprot id: B4S3H1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

290512:PAES RS00595
gene id: 290512:PAES_RS00595
uniprot id: B4S388
names: Similarity
messages: Belongs to the acylphosphatase family.

290512:PAES RS00970
gene id: 290512:PAES_RS00970
uniprot id: B4S3Q6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

290512:PAES RS00745
gene id: 290512:PAES_RS00745
uniprot id: B4S3B3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

290512:PAES RS01515
gene id: 290512:PAES_RS01515
uniprot id: B4S4B1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

290512:PAES RS03720
gene id: 290512:PAES_RS03720
uniprot id: B4S6N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

290512:PAES RS03765
gene id: 290512:PAES_RS03765
uniprot id: B4S6P3
names: Similarity
messages: Belongs to the Pal lipoprotein family.

290512:PAES RS02025
gene id: 290512:PAES_RS02025
uniprot id: B4S4W0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

290512:PAES RS11175
gene id: 290512:PAES_RS11175
uniprot id: B4S6E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a, b, b' and c.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

290512:PAES RS08520
gene id: 290512:PAES_RS08520
uniprot id: B4S3I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

290512:PAES RS10215
gene id: 290512:PAES_RS10215
uniprot id: B4S5B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

290512:PAES RS03910
gene id: 290512:PAES_RS03910
uniprot id: B4S6Z3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

290512:PAES RS06410
gene id: 290512:PAES_RS06410
uniprot id: B4S8B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

290512:PAES RS03745
gene id: 290512:PAES_RS03745
uniprot id: B4S6N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

290512:PAES RS04320
gene id: 290512:PAES_RS04320
uniprot id: B4S768
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

290512:PAES RS08165
gene id: 290512:PAES_RS08165
uniprot id: B4S9I2
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

290512:PAES RS11215
gene id: 290512:PAES_RS11215
uniprot id: B4S6F3
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

290512:PAES RS05640
gene id: 290512:PAES_RS05640
uniprot id: B4S7X0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

290512:PAES RS00750
gene id: 290512:PAES_RS00750
uniprot id: B4S3B4
names: Similarity
messages: Belongs to the Fur family.

290512:PAES RS10160
gene id: 290512:PAES_RS10160
uniprot id: B4S5A1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

290512:PAES RS03970
gene id: 290512:PAES_RS03970
uniprot id: B4S705
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

290512:PAES RS09245
gene id: 290512:PAES_RS09245
uniprot id: B4S473
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

290512:PAES RS04090
gene id: 290512:PAES_RS04090
uniprot id: B4S724
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

290512:PAES RS01835
gene id: 290512:PAES_RS01835
uniprot id: B4S4S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

290512:PAES RS06435
gene id: 290512:PAES_RS06435
uniprot id: B4S8C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

290512:PAES RS09330
gene id: 290512:PAES_RS09330
uniprot id: B4S4I6
names: Similarity
messages: Belongs to the citrate synthase family.

290512:PAES RS05600
gene id: 290512:PAES_RS05600
uniprot id: B4S7W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

290512:PAES RS12065
gene id: 290512:PAES_RS12065
uniprot id: B4S8I9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

290512:PAES RS07350
gene id: 290512:PAES_RS07350
uniprot id: B4S8V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

290512:PAES RS03355
gene id: 290512:PAES_RS03355
uniprot id: B4S6G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

290512:PAES RS10580
gene id: 290512:PAES_RS10580
uniprot id: B4S5T1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

290512:PAES RS09435
gene id: 290512:PAES_RS09435
uniprot id: B4S4K6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

290512:PAES RS08975
gene id: 290512:PAES_RS08975
uniprot id: B4S418
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

290512:PAES RS02160
gene id: 290512:PAES_RS02160
uniprot id: B4S4Y8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

290512:PAES RS09755
gene id: 290512:PAES_RS09755
uniprot id: B4S4S1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

290512:PAES RS08010
gene id: 290512:PAES_RS08010
uniprot id: B4S9F1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

290512:PAES RS07965
gene id: 290512:PAES_RS07965
uniprot id: B4S9E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

290512:PAES RS08690
gene id: 290512:PAES_RS08690
uniprot id: B4S3L8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

290512:PAES RS07490
gene id: 290512:PAES_RS07490
uniprot id: B4S8Y1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

290512:PAES RS10015
gene id: 290512:PAES_RS10015
uniprot id: B4S572
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS05100
gene id: 290512:PAES_RS05100
uniprot id: B4S7L7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

290512:PAES RS05540
gene id: 290512:PAES_RS05540
uniprot id: B4S7V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

290512:PAES RS06465
gene id: 290512:PAES_RS06465
uniprot id: B4S8C8
names: Similarity
messages: Belongs to the CobH/CbiC family.

290512:PAES RS01260
gene id: 290512:PAES_RS01260
uniprot id: B4S3W5
names: Similarity
messages: Belongs to the universal stress protein A family.

290512:PAES RS02990
gene id: 290512:PAES_RS02990
uniprot id: B4S605
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

290512:PAES RS10230
gene id: 290512:PAES_RS10230
uniprot id: B4S5B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

290512:PAES RS04950
gene id: 290512:PAES_RS04950
uniprot id: B4S7I7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS08435
gene id: 290512:PAES_RS08435
uniprot id: B4S3G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

290512:PAES RS04375
gene id: 290512:PAES_RS04375
uniprot id: B4S779
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS02795
gene id: 290512:PAES_RS02795
uniprot id: B4S5M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

290512:PAES RS02000
gene id: 290512:PAES_RS02000
uniprot id: B4S4V5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

290512:PAES RS07360
gene id: 290512:PAES_RS07360
uniprot id: B4S8V5
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS07930
gene id: 290512:PAES_RS07930
uniprot id: B4S9D5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

290512:PAES RS01290
gene id: 290512:PAES_RS01290
uniprot id: B4S3X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

290512:PAES RS10295
gene id: 290512:PAES_RS10295
uniprot id: B4S5M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

290512:PAES RS04755
gene id: 290512:PAES_RS04755
uniprot id: B4S7E9
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

290512:PAES RS07460
gene id: 290512:PAES_RS07460
uniprot id: B4S8X5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

290512:PAES RS05040
gene id: 290512:PAES_RS05040
uniprot id: B4S7K5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

290512:PAES RS01240
gene id: 290512:PAES_RS01240
uniprot id: B4S3W0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

290512:PAES RS01930
gene id: 290512:PAES_RS01930
uniprot id: B4S4U3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS09730
gene id: 290512:PAES_RS09730
uniprot id: B4S4R6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

290512:PAES RS04550
gene id: 290512:PAES_RS04550
uniprot id: B4S7A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

290512:PAES RS08660
gene id: 290512:PAES_RS08660
uniprot id: B4S3L2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

290512:PAES RS10075
gene id: 290512:PAES_RS10075
uniprot id: B4S584
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

290512:PAES RS03685
gene id: 290512:PAES_RS03685
uniprot id: B4S6M7
names: Similarity
messages: Belongs to the UPF0758 family.

290512:PAES RS06775
gene id: 290512:PAES_RS06775
uniprot id: B4S8I8
names: Similarity
messages: Belongs to the arsA ATPase family.

290512:PAES RS01675
gene id: 290512:PAES_RS01675
uniprot id: B4S4E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

290512:PAES RS09420
gene id: 290512:PAES_RS09420
uniprot id: B4S4K3
names: Similarity
messages: Belongs to the ParB family.

290512:PAES RS01055
gene id: 290512:PAES_RS01055
uniprot id: B4S3S2
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

290512:PAES RS09455
gene id: 290512:PAES_RS09455
uniprot id: B4S4L0
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

290512:PAES RS00890
gene id: 290512:PAES_RS00890
uniprot id: B4S3P0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

290512:PAES RS05035
gene id: 290512:PAES_RS05035
uniprot id: B4S7K4
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS00720
gene id: 290512:PAES_RS00720
uniprot id: B4S3A8
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

290512:PAES RS02900
gene id: 290512:PAES_RS02900
uniprot id: B4S5Y7
names: Similarity
messages: Belongs to the CarB family.

290512:PAES RS10120
gene id: 290512:PAES_RS10120
uniprot id: B4S593
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BchN/ChlN family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

290512:PAES RS01280
gene id: 290512:PAES_RS01280
uniprot id: B4S3X0
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

290512:PAES RS10765
gene id: 290512:PAES_RS10765
uniprot id: B4S5W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

290512:PAES RS10285
gene id: 290512:PAES_RS10285
uniprot id: B4S5M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

290512:PAES RS11335
gene id: 290512:PAES_RS11335
uniprot id: B4S6S4
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS09380
gene id: 290512:PAES_RS09380
uniprot id: B4S4J6
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS03575
gene id: 290512:PAES_RS03575
uniprot id: B4S6K6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

290512:PAES RS08210
gene id: 290512:PAES_RS08210
uniprot id: B4S9J1
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

290512:PAES RS02585
gene id: 290512:PAES_RS02585
uniprot id: B4S5H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

290512:PAES RS08615
gene id: 290512:PAES_RS08615
uniprot id: B4S3K2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

290512:PAES RS09570
gene id: 290512:PAES_RS09570
uniprot id: B4S4N3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS06260
gene id: 290512:PAES_RS06260
uniprot id: B4S888
names: Similarity
messages: Belongs to the UPF0251 family.

290512:PAES RS11135
gene id: 290512:PAES_RS11135
uniprot id: B4S6D9
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

290512:PAES RS11005
gene id: 290512:PAES_RS11005
uniprot id: B4S6B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

290512:PAES RS04545
gene id: 290512:PAES_RS04545
uniprot id: B4S7A8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

290512:PAES RS08630
gene id: 290512:PAES_RS08630
uniprot id: B4S3K5
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

290512:PAES RS04295
gene id: 290512:PAES_RS04295
uniprot id: B4S763
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

290512:PAES RS07805
gene id: 290512:PAES_RS07805
uniprot id: B4S9B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

290512:PAES RS07455
gene id: 290512:PAES_RS07455
uniprot id: B4S8X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

290512:PAES RS09510
gene id: 290512:PAES_RS09510
uniprot id: B4S4M1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

290512:PAES RS02330
gene id: 290512:PAES_RS02330
uniprot id: B4S5C5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

290512:PAES RS00965
gene id: 290512:PAES_RS00965
uniprot id: B4S3Q5
names: Similarity
messages: Belongs to the UPF0166 family.

290512:PAES RS07575
gene id: 290512:PAES_RS07575
uniprot id: B4S8Z8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS11160
gene id: 290512:PAES_RS11160
uniprot id: B4S6E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

290512:PAES RS10350
gene id: 290512:PAES_RS10350
uniprot id: B4S5N9
names: Subcellular Location Annotation
messages: Cytoplasm

290512:PAES RS01435
gene id: 290512:PAES_RS01435
uniprot id: B4S494
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

290512:PAES RS02035
gene id: 290512:PAES_RS02035
uniprot id: B4S4W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

290512:PAES RS00925
gene id: 290512:PAES_RS00925
uniprot id: B4S3P7
names: Similarity
messages: Belongs to the Fur family.

290512:PAES RS01285
gene id: 290512:PAES_RS01285
uniprot id: B4S3X1
names: Similarity
messages: Belongs to the threonine synthase family.

290512:PAES RS10630
gene id: 290512:PAES_RS10630
uniprot id: B4S5U1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

290512:PAES RS00940
gene id: 290512:PAES_RS00940
uniprot id: B4S3Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

290512:PAES RS11895
gene id: 290512:PAES_RS11895
uniprot id: B4S9Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

290512:PAES RS09980
gene id: 290512:PAES_RS09980
uniprot id: B4S564
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

290512:PAES RS10520
gene id: 290512:PAES_RS10520
uniprot id: B4S5S1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

290512:PAES RS01380
gene id: 290512:PAES_RS01380
uniprot id: B4S487
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

290512:PAES RS11920
gene id: 290512:PAES_RS11920
uniprot id: B4S9R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TraY family.
messages: Cytoplasm

290512:PAES RS02205
gene id: 290512:PAES_RS02205
uniprot id: B4S4Z7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

290512:PAES RS00120
gene id: 290512:PAES_RS00120
uniprot id: B4S958
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

290512:PAES RS08750
gene id: 290512:PAES_RS08750
uniprot id: B4S3N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

290512:PAES RS09150
gene id: 290512:PAES_RS09150
uniprot id: B4S454
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS03045
gene id: 290512:PAES_RS03045
uniprot id: B4S616
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

290512:PAES RS11255
gene id: 290512:PAES_RS11255
uniprot id: B4S6Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

290512:PAES RS00895
gene id: 290512:PAES_RS00895
uniprot id: B4S3P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

290512:PAES RS00035
gene id: 290512:PAES_RS00035
uniprot id: B4S941
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

290512:PAES RS06275
gene id: 290512:PAES_RS06275
uniprot id: B4S891
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

290512:PAES RS01855
gene id: 290512:PAES_RS01855
uniprot id: B4S4S8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

290512:PAES RS08020
gene id: 290512:PAES_RS08020
uniprot id: B4S9F3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

290512:PAES RS11065
gene id: 290512:PAES_RS11065
uniprot id: B4S6C5
names: Similarity
messages: Belongs to the alkaline phosphatase family.

290512:PAES RS09030
gene id: 290512:PAES_RS09030
uniprot id: B4S429
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

290512:PAES RS02740
gene id: 290512:PAES_RS02740
uniprot id: B4S5L0
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS09590
gene id: 290512:PAES_RS09590
uniprot id: B4S4N7
names: Similarity
messages: Belongs to the universal stress protein A family.

290512:PAES RS07690
gene id: 290512:PAES_RS07690
uniprot id: B4S921
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

290512:PAES RS06540
gene id: 290512:PAES_RS06540
uniprot id: B4S8E3
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS09225
gene id: 290512:PAES_RS09225
uniprot id: B4S469
names: Similarity
messages: Belongs to the LOG family.

290512:PAES RS08300
gene id: 290512:PAES_RS08300
uniprot id: B4S3E0
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

290512:PAES RS11495
gene id: 290512:PAES_RS11495
uniprot id: B4S6V5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

290512:PAES RS01420
gene id: 290512:PAES_RS01420
uniprot id: B4S491
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

290512:PAES RS06005
gene id: 290512:PAES_RS06005
uniprot id: B4S842
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

290512:PAES RS03740
gene id: 290512:PAES_RS03740
uniprot id: B4S6N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

290512:PAES RS08045
gene id: 290512:PAES_RS08045
uniprot id: B4S9F8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

290512:PAES RS08680
gene id: 290512:PAES_RS08680
uniprot id: B4S3L6
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

290512:PAES RS12140
gene id: 290512:PAES_RS12140
uniprot id: B4S6A7
names: Similarity
messages: Belongs to the alkaline phosphatase family.

290512:PAES RS02720
gene id: 290512:PAES_RS02720
uniprot id: B4S5K6
names: Similarity
messages: Belongs to the peptidase M24B family.

290512:PAES RS08355
gene id: 290512:PAES_RS08355
uniprot id: B4S3F1
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS08225
gene id: 290512:PAES_RS08225
uniprot id: B4S9J4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

290512:PAES RS00080
gene id: 290512:PAES_RS00080
uniprot id: B4S950
names: Similarity
messages: Belongs to the UPF0102 family.

290512:PAES RS07910
gene id: 290512:PAES_RS07910
uniprot id: B4S9D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

290512:PAES RS03065
gene id: 290512:PAES_RS03065
uniprot id: B4S620
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

290512:PAES RS10105
gene id: 290512:PAES_RS10105
uniprot id: B4S590
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

290512:PAES RS04385
gene id: 290512:PAES_RS04385
uniprot id: B4S781
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

290512:PAES RS11240
gene id: 290512:PAES_RS11240
uniprot id: B4S6F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

290512:PAES RS07195
gene id: 290512:PAES_RS07195
uniprot id: B4S8S3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

290512:PAES RS01670
gene id: 290512:PAES_RS01670
uniprot id: B4S4E1
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

290512:PAES RS10650
gene id: 290512:PAES_RS10650
uniprot id: B4S5U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

290512:PAES RS03880
gene id: 290512:PAES_RS03880
uniprot id: B4S6Y6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

290512:PAES RS08790
gene id: 290512:PAES_RS08790
uniprot id: B4S3Y3
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

290512:PAES RS05850
gene id: 290512:PAES_RS05850
uniprot id: B4S810
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

290512:PAES RS10265
gene id: 290512:PAES_RS10265
uniprot id: B4S5C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

290512:PAES RS12115
gene id: 290512:PAES_RS12115
uniprot id: B4S4M4
names: Subcellular Location Annotation
messages: Cell inner membrane

290512:PAES RS00005
gene id: 290512:PAES_RS00005
uniprot id: B4S935
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

290512:PAES RS09050
gene id: 290512:PAES_RS09050
uniprot id: B4S433
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

290512:PAES RS09365
gene id: 290512:PAES_RS09365
uniprot id: B4S4J3
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

290512:PAES RS02905
gene id: 290512:PAES_RS02905
uniprot id: B4S5Y8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

290512:PAES RS10920
gene id: 290512:PAES_RS10920
uniprot id: B4S695
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

290512:PAES RS02445
gene id: 290512:PAES_RS02445
uniprot id: B4S5E9
names: Similarity
messages: Belongs to the TrpC family.

290512:PAES RS08145
gene id: 290512:PAES_RS08145
uniprot id: B4S9H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

290512:PAES RS10775
gene id: 290512:PAES_RS10775
uniprot id: B4S665
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

290512:PAES RS02295
gene id: 290512:PAES_RS02295
uniprot id: B4S517
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

290512:PAES RS11930
gene id: 290512:PAES_RS11930
uniprot id: B4S979
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS00475
gene id: 290512:PAES_RS00475
uniprot id: B4S365
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

290512:PAES RS10210
gene id: 290512:PAES_RS10210
uniprot id: B4S5B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

290512:PAES RS11115
gene id: 290512:PAES_RS11115
uniprot id: B4S6D5
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

290512:PAES RS08315
gene id: 290512:PAES_RS08315
uniprot id: B4S3E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

290512:PAES RS04000
gene id: 290512:PAES_RS04000
uniprot id: B4S711
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

290512:PAES RS02175
gene id: 290512:PAES_RS02175
uniprot id: B4S4Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

290512:PAES RS03510
gene id: 290512:PAES_RS03510
uniprot id: B4S6J3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

290512:PAES RS00585
gene id: 290512:PAES_RS00585
uniprot id: B4S387
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

290512:PAES RS00215
gene id: 290512:PAES_RS00215
uniprot id: B4S977
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

290512:PAES RS00435
gene id: 290512:PAES_RS00435
uniprot id: B4S357
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS12050
gene id: 290512:PAES_RS12050
uniprot id: B4S8C4
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

290512:PAES RS10025
gene id: 290512:PAES_RS10025
uniprot id: B4S574
names: Similarity
messages: Belongs to the peptidase S11 family.

290512:PAES RS01935
gene id: 290512:PAES_RS01935
uniprot id: B4S4U4
names: Subcellular Location Annotation
messages: Membrane

290512:PAES RS00030
gene id: 290512:PAES_RS00030
uniprot id: B4S940
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

290512:PAES RS09110
gene id: 290512:PAES_RS09110
uniprot id: B4S446
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

290512:PAES RS09850
gene id: 290512:PAES_RS09850
uniprot id: B4S540
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

290512:PAES RS02305
gene id: 290512:PAES_RS02305
uniprot id: B4S519
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

290512:PAES RS01705
gene id: 290512:PAES_RS01705
uniprot id: B4S4E8
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

290512:PAES RS10190
gene id: 290512:PAES_RS10190
uniprot id: B4S5A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

290512:PAES RS01445
gene id: 290512:PAES_RS01445
uniprot id: B4S496
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

290512:PAES RS01110
gene id: 290512:PAES_RS01110
uniprot id: B4S3T3
names: Similarity
messages: Belongs to the arsA ATPase family.

290512:PAES RS00115
gene id: 290512:PAES_RS00115
uniprot id: B4S957
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. ChlP subfamily.