288004:AL038 RS09990
gene id: 288004:AL038_RS09990
uniprot id: A0A2N9YGY1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

288004:AL038 RS05820
gene id: 288004:AL038_RS05820
uniprot id: A0A2N9Y9X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

288004:AL038 RS07365
gene id: 288004:AL038_RS07365
uniprot id: A0A2N9YI89
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

288004:AL038 RS05225
gene id: 288004:AL038_RS05225
uniprot id: A0A2N9YA89
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

288004:AL038 RS10715
gene id: 288004:AL038_RS10715
uniprot id: A0A2N9YGH8
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

288004:AL038 RS01235
gene id: 288004:AL038_RS01235
uniprot id: A0A2N9YCD6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

288004:AL038 RS10955
gene id: 288004:AL038_RS10955
uniprot id: A0A2N9YGI0
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS01550
gene id: 288004:AL038_RS01550
uniprot id: A0A2N9YC54
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

288004:AL038 RS07890
gene id: 288004:AL038_RS07890
uniprot id: A0A2N9YI01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

288004:AL038 RS03150
gene id: 288004:AL038_RS03150
uniprot id: A0A2N9YBE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

288004:AL038 RS13910
gene id: 288004:AL038_RS13910
uniprot id: A0A2N9YF18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

288004:AL038 RS06300
gene id: 288004:AL038_RS06300
uniprot id: A0A2N9YIV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

288004:AL038 RS11815
gene id: 288004:AL038_RS11815
uniprot id: A0A2N9YFY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS14390
gene id: 288004:AL038_RS14390
uniprot id: A0A2N9YES2
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS00925
gene id: 288004:AL038_RS00925
uniprot id: A0A2N9YCE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

288004:AL038 RS07160
gene id: 288004:AL038_RS07160
uniprot id: A0A2N9YIE0
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

288004:AL038 RS15310
gene id: 288004:AL038_RS15310
uniprot id: A0A2N9YEC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

288004:AL038 RS00525
gene id: 288004:AL038_RS00525
uniprot id: A0A2N9YCL2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

288004:AL038 RS07115
gene id: 288004:AL038_RS07115
uniprot id: A0A2N9YIN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

288004:AL038 RS13960
gene id: 288004:AL038_RS13960
uniprot id: A0A2N9YF04
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

288004:AL038 RS15440
gene id: 288004:AL038_RS15440
uniprot id: A0A2N9YE84
names: Similarity
messages: Belongs to the thioredoxin family.

288004:AL038 RS02260
gene id: 288004:AL038_RS02260
uniprot id: A0A2N9YBN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

288004:AL038 RS06950
gene id: 288004:AL038_RS06950
uniprot id: A0A2N9YIG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

288004:AL038 RS06215
gene id: 288004:AL038_RS06215
uniprot id: A0A2N9YJI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

288004:AL038 RS15140
gene id: 288004:AL038_RS15140
uniprot id: A0A2N9YEI6
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

288004:AL038 RS14225
gene id: 288004:AL038_RS14225
uniprot id: A0A2N9YEU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

288004:AL038 RS04465
gene id: 288004:AL038_RS04465
uniprot id: A0A2N9YAL3
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

288004:AL038 RS12785
gene id: 288004:AL038_RS12785
uniprot id: A0A2N9YFJ6
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

288004:AL038 RS01130
gene id: 288004:AL038_RS01130
uniprot id: A0A2N9YCC2
names: Similarity
messages: Belongs to the WrbA family.

288004:AL038 RS12920
gene id: 288004:AL038_RS12920
uniprot id: A0A2N9YFD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

288004:AL038 RS17055
gene id: 288004:AL038_RS17055
uniprot id: A0A2N9YDE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

288004:AL038 RS15795
gene id: 288004:AL038_RS15795
uniprot id: A0A2N9YE33
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS06465
gene id: 288004:AL038_RS06465
uniprot id: A0A2N9YIM6
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

288004:AL038 RS14840
gene id: 288004:AL038_RS14840
uniprot id: A0A2N9YEN7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

288004:AL038 RS15965
gene id: 288004:AL038_RS15965
uniprot id: A0A2N9YDZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

288004:AL038 RS02825
gene id: 288004:AL038_RS02825
uniprot id: A0A2N9YBK6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS13230
gene id: 288004:AL038_RS13230
uniprot id: A0A2N9YFB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

288004:AL038 RS08110
gene id: 288004:AL038_RS08110
uniprot id: A0A2N9YHT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS13745
gene id: 288004:AL038_RS13745
uniprot id: A0A2N9YF45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

288004:AL038 RS15700
gene id: 288004:AL038_RS15700
uniprot id: A0A2N9YE38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

288004:AL038 RS01455
gene id: 288004:AL038_RS01455
uniprot id: A0A2N9YC78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

288004:AL038 RS06290
gene id: 288004:AL038_RS06290
uniprot id: A0A2N9YIT5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

288004:AL038 RS05670
gene id: 288004:AL038_RS05670
uniprot id: A0A2N9YA06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

288004:AL038 RS09900
gene id: 288004:AL038_RS09900
uniprot id: A0A2N9YGX0
names: Similarity
messages: Belongs to the intimin/invasin family.

288004:AL038 RS08600
gene id: 288004:AL038_RS08600
uniprot id: A0A2N9YHM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

288004:AL038 RS08170
gene id: 288004:AL038_RS08170
uniprot id: A0A2N9YHQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

288004:AL038 RS05200
gene id: 288004:AL038_RS05200
uniprot id: A0A2N9YAB0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS08800
gene id: 288004:AL038_RS08800
uniprot id: A0A2N9YHK3
names: Similarity
messages: Belongs to the band 7/mec-2 family.

288004:AL038 RS04745
gene id: 288004:AL038_RS04745
uniprot id: A0A2N9YAH0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

288004:AL038 RS09220
gene id: 288004:AL038_RS09220
uniprot id: A0A2N9YH95
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

288004:AL038 RS07510
gene id: 288004:AL038_RS07510
uniprot id: A0A2N9YI28
names: Similarity
messages: Belongs to the DsrF/TusC family.

288004:AL038 RS15255
gene id: 288004:AL038_RS15255
uniprot id: A0A2N9YEG5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

288004:AL038 RS06775
gene id: 288004:AL038_RS06775
uniprot id: A0A2N9YIT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

288004:AL038 RS03655
gene id: 288004:AL038_RS03655
uniprot id: A0A2N9YB22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

288004:AL038 RS09605
gene id: 288004:AL038_RS09605
uniprot id: A0A2N9YH70
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

288004:AL038 RS03810
gene id: 288004:AL038_RS03810
uniprot id: A0A2N9YAY1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

288004:AL038 RS12370
gene id: 288004:AL038_RS12370
uniprot id: A0A2N9YJH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

288004:AL038 RS00905
gene id: 288004:AL038_RS00905
uniprot id: A0A2N9YCF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

288004:AL038 RS16910
gene id: 288004:AL038_RS16910
uniprot id: A0A2N9YDJ2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

288004:AL038 RS08080
gene id: 288004:AL038_RS08080
uniprot id: A0A2N9YHT7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

288004:AL038 RS02470
gene id: 288004:AL038_RS02470
uniprot id: A0A2N9YBQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

288004:AL038 RS15275
gene id: 288004:AL038_RS15275
uniprot id: A0A2N9YEB1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

288004:AL038 RS06680
gene id: 288004:AL038_RS06680
uniprot id: A0A2N9YJ25
names: Function
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.
messages: Involved in the high-affinity zinc uptake transport system.

288004:AL038 RS15330
gene id: 288004:AL038_RS15330
uniprot id: A0A2N9YEA3
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

288004:AL038 RS09660
gene id: 288004:AL038_RS09660
uniprot id: A0A2N9YGX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

288004:AL038 RS13935
gene id: 288004:AL038_RS13935
uniprot id: A0A2N9YF88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

288004:AL038 RS02800
gene id: 288004:AL038_RS02800
uniprot id: A0A2N9YBL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

288004:AL038 RS04645
gene id: 288004:AL038_RS04645
uniprot id: A0A2N9YAI7
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS03075
gene id: 288004:AL038_RS03075
uniprot id: A0A2N9YBA7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

288004:AL038 RS11450
gene id: 288004:AL038_RS11450
uniprot id: A0A2N9YG85
names: Similarity
messages: Belongs to the pirin family.

288004:AL038 RS08805
gene id: 288004:AL038_RS08805
uniprot id: A0A2N9YIC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

288004:AL038 RS00560
gene id: 288004:AL038_RS00560
uniprot id: A0A2N9YCL8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

288004:AL038 RS01160
gene id: 288004:AL038_RS01160
uniprot id: A0A2N9YC81
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

288004:AL038 RS06220
gene id: 288004:AL038_RS06220
uniprot id: A0A2N9YJ98
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-67 and Arg-70) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

288004:AL038 RS13830
gene id: 288004:AL038_RS13830
uniprot id: A0A2N9YFB1
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

288004:AL038 RS17865
gene id: 288004:AL038_RS17865
uniprot id: A0A2N9YD30
names: Cofactor
messages: Can also use Mn(2+) ion.

288004:AL038 RS10145
gene id: 288004:AL038_RS10145
uniprot id: A0A2N9YGV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

288004:AL038 RS17870
gene id: 288004:AL038_RS17870
uniprot id: A0A2N9YDD1
names: Similarity
messages: Belongs to the malate synthase family.

288004:AL038 RS17370
gene id: 288004:AL038_RS17370
uniprot id: A0A2N9YD89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

288004:AL038 RS04730
gene id: 288004:AL038_RS04730
uniprot id: A0A2N9YAJ2
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

288004:AL038 RS00485
gene id: 288004:AL038_RS00485
uniprot id: A0A2N9YCM8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS16605
gene id: 288004:AL038_RS16605
uniprot id: A0A2N9YDN2
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

288004:AL038 RS02105
gene id: 288004:AL038_RS02105
uniprot id: A0A2N9YC06
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS04050
gene id: 288004:AL038_RS04050
uniprot id: A0A2N9YAV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

288004:AL038 RS07280
gene id: 288004:AL038_RS07280
uniprot id: A0A2N9YI67
names: Similarity
messages: Belongs to the TPP enzyme family.

288004:AL038 RS09080
gene id: 288004:AL038_RS09080
uniprot id: A0A2N9YHG2
names: Similarity
messages: Belongs to the asparagine synthetase family.

288004:AL038 RS03865
gene id: 288004:AL038_RS03865
uniprot id: A0A2N9YAZ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

288004:AL038 RS07860
gene id: 288004:AL038_RS07860
uniprot id: A0A2N9YIV1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

288004:AL038 RS17290
gene id: 288004:AL038_RS17290
uniprot id: A0A2N9YD90
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

288004:AL038 RS06250
gene id: 288004:AL038_RS06250
uniprot id: A0A2N9YIU1
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

288004:AL038 RS05480
gene id: 288004:AL038_RS05480
uniprot id: A0A2N9YA50
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS02580
gene id: 288004:AL038_RS02580
uniprot id: A0A2N9YBJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

288004:AL038 RS14355
gene id: 288004:AL038_RS14355
uniprot id: A0A2N9YF52
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

288004:AL038 RS12700
gene id: 288004:AL038_RS12700
uniprot id: A0A2N9YFX3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

288004:AL038 RS08265
gene id: 288004:AL038_RS08265
uniprot id: A0A2N9YIM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

288004:AL038 RS14885
gene id: 288004:AL038_RS14885
uniprot id: A0A2N9YEH6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

288004:AL038 RS17380
gene id: 288004:AL038_RS17380
uniprot id: A0A2N9YDA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

288004:AL038 RS14000
gene id: 288004:AL038_RS14000
uniprot id: A0A2N9YF00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

288004:AL038 RS07305
gene id: 288004:AL038_RS07305
uniprot id: A0A2N9YI79
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

288004:AL038 RS08620
gene id: 288004:AL038_RS08620
uniprot id: A0A2N9YIF2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS17755
gene id: 288004:AL038_RS17755
uniprot id: A0A2N9YD17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS12965
gene id: 288004:AL038_RS12965
uniprot id: A0A2N9YFH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

288004:AL038 RS17115
gene id: 288004:AL038_RS17115
uniprot id: A0A2N9YDC8
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

288004:AL038 RS06955
gene id: 288004:AL038_RS06955
uniprot id: A0A2N9YJP7
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

288004:AL038 RS07055
gene id: 288004:AL038_RS07055
uniprot id: A0A2N9YIP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

288004:AL038 RS09810
gene id: 288004:AL038_RS09810
uniprot id: A0A2N9YH09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

288004:AL038 RS15260
gene id: 288004:AL038_RS15260
uniprot id: A0A2N9YEL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

288004:AL038 RS11240
gene id: 288004:AL038_RS11240
uniprot id: A0A2N9YGA8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS15125
gene id: 288004:AL038_RS15125
uniprot id: A0A2N9YET4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

288004:AL038 RS15485
gene id: 288004:AL038_RS15485
uniprot id: A0A2N9YEA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

288004:AL038 RS08035
gene id: 288004:AL038_RS08035
uniprot id: A0A2N9YIA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

288004:AL038 RS03765
gene id: 288004:AL038_RS03765
uniprot id: A0A2N9YB03
names: Similarity
messages: Belongs to the NifX/NifY family.

288004:AL038 RS11810
gene id: 288004:AL038_RS11810
uniprot id: A0A2N9YGB2
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

288004:AL038 RS03175
gene id: 288004:AL038_RS03175
uniprot id: A0A2N9YB86
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

288004:AL038 RS05540
gene id: 288004:AL038_RS05540
uniprot id: A0A2N9YA29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

288004:AL038 RS08380
gene id: 288004:AL038_RS08380
uniprot id: A0A2N9YHR9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS15745
gene id: 288004:AL038_RS15745
uniprot id: A0A2N9YE41
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

288004:AL038 RS07650
gene id: 288004:AL038_RS07650
uniprot id: A0A2N9YIY6
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

288004:AL038 RS14795
gene id: 288004:AL038_RS14795
uniprot id: A0A2N9YES1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

288004:AL038 RS08930
gene id: 288004:AL038_RS08930
uniprot id: A0A2N9YHL1
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

288004:AL038 RS10040
gene id: 288004:AL038_RS10040
uniprot id: A0A2N9YGX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS10030
gene id: 288004:AL038_RS10030
uniprot id: A0A2N9YH69
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

288004:AL038 RS15150
gene id: 288004:AL038_RS15150
uniprot id: A0A2N9YEG8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

288004:AL038 RS04440
gene id: 288004:AL038_RS04440
uniprot id: A0A2N9YAN5
names: Similarity
messages: Belongs to the peptidase U62 family.

288004:AL038 RS00720
gene id: 288004:AL038_RS00720
uniprot id: A0A2N9YCM6
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

288004:AL038 RS00895
gene id: 288004:AL038_RS00895
uniprot id: A0A2N9YCG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

288004:AL038 RS04860
gene id: 288004:AL038_RS04860
uniprot id: A0A2N9YAE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

288004:AL038 RS16245
gene id: 288004:AL038_RS16245
uniprot id: A0A0N9M4S5
names: Subcellular Location Annotation
messages: Cytoplasm

288004:AL038 RS07090
gene id: 288004:AL038_RS07090
uniprot id: A0A2N9YIE8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

288004:AL038 RS17570
gene id: 288004:AL038_RS17570
uniprot id: A0A2N9YD57
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

288004:AL038 RS10260
gene id: 288004:AL038_RS10260
uniprot id: A0A2N9YH42
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

288004:AL038 RS18010
gene id: 288004:AL038_RS18010
uniprot id: A0A2N9YD19
names: Similarity
messages: Belongs to the PrpF family.

288004:AL038 RS04015
gene id: 288004:AL038_RS04015
uniprot id: A0A2N9YAT0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

288004:AL038 RS09305
gene id: 288004:AL038_RS09305
uniprot id: A0A2N9YH44
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS04505
gene id: 288004:AL038_RS04505
uniprot id: A0A2N9YAM2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

288004:AL038 RS13950
gene id: 288004:AL038_RS13950
uniprot id: A0A2N9YF07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

288004:AL038 RS01830
gene id: 288004:AL038_RS01830
uniprot id: A0A2N9YC03
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS13650
gene id: 288004:AL038_RS13650
uniprot id: A0A2N9YF73
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

288004:AL038 RS05440
gene id: 288004:AL038_RS05440
uniprot id: A0A2N9YA52
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

288004:AL038 RS00305
gene id: 288004:AL038_RS00305
uniprot id: A0A2N9YCR8
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

288004:AL038 RS14110
gene id: 288004:AL038_RS14110
uniprot id: A0A2N9YEX2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

288004:AL038 RS07615
gene id: 288004:AL038_RS07615
uniprot id: A0A2N9YI96
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

288004:AL038 RS13035
gene id: 288004:AL038_RS13035
uniprot id: A0A2N9YG95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

288004:AL038 RS02080
gene id: 288004:AL038_RS02080
uniprot id: A0A2N9YJ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS14290
gene id: 288004:AL038_RS14290
uniprot id: A0A2N9YEU2
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

288004:AL038 RS11245
gene id: 288004:AL038_RS11245
uniprot id: A0A2N9YGC8
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS11375
gene id: 288004:AL038_RS11375
uniprot id: A0A2N9YG56
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

288004:AL038 RS06410
gene id: 288004:AL038_RS06410
uniprot id: A0A2N9YIN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

288004:AL038 RS13580
gene id: 288004:AL038_RS13580
uniprot id: A0A650GDY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

288004:AL038 RS10660
gene id: 288004:AL038_RS10660
uniprot id: A0A2N9YGI8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

288004:AL038 RS02740
gene id: 288004:AL038_RS02740
uniprot id: A0A2N9YBH8
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

288004:AL038 RS15695
gene id: 288004:AL038_RS15695
uniprot id: A0A2N9YEI3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

288004:AL038 RS03370
gene id: 288004:AL038_RS03370
uniprot id: A0A2N9YB64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

288004:AL038 RS07145
gene id: 288004:AL038_RS07145
uniprot id: A0A2N9YIF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

288004:AL038 RS10875
gene id: 288004:AL038_RS10875
uniprot id: A0A2N9YGH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

288004:AL038 RS11380
gene id: 288004:AL038_RS11380
uniprot id: A0A2N9YG92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

288004:AL038 RS12505
gene id: 288004:AL038_RS12505
uniprot id: A0A2N9YFN0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

288004:AL038 RS15780
gene id: 288004:AL038_RS15780
uniprot id: A0A2N9YE25
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS05445
gene id: 288004:AL038_RS05445
uniprot id: A0A2N9YA70
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

288004:AL038 RS00400
gene id: 288004:AL038_RS00400
uniprot id: A0A2N9YCQ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

288004:AL038 RS07760
gene id: 288004:AL038_RS07760
uniprot id: A0A2N9YIX0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

288004:AL038 RS13855
gene id: 288004:AL038_RS13855
uniprot id: A0A2N9YF12
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

288004:AL038 RS10695
gene id: 288004:AL038_RS10695
uniprot id: A0A2N9YGI4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

288004:AL038 RS00520
gene id: 288004:AL038_RS00520
uniprot id: A0A2N9YCM4
names: Similarity
messages: Belongs to the transglycosylase Slt family.

288004:AL038 RS01320
gene id: 288004:AL038_RS01320
uniprot id: A0A2N9YC86
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

288004:AL038 RS03805
gene id: 288004:AL038_RS03805
uniprot id: A0A2N9YB05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

288004:AL038 RS13645
gene id: 288004:AL038_RS13645
uniprot id: A0A2N9YF56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

288004:AL038 RS14335
gene id: 288004:AL038_RS14335
uniprot id: A0A2N9YET2
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS09175
gene id: 288004:AL038_RS09175
uniprot id: A0A2N9YI61
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS16875
gene id: 288004:AL038_RS16875
uniprot id: A0A2N9YDI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

288004:AL038 RS01605
gene id: 288004:AL038_RS01605
uniprot id: A0A2N9YC22
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

288004:AL038 RS06590
gene id: 288004:AL038_RS06590
uniprot id: A0A2N9YIN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

288004:AL038 RS03750
gene id: 288004:AL038_RS03750
uniprot id: A0A2N9YB20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

288004:AL038 RS12270
gene id: 288004:AL038_RS12270
uniprot id: A0A2N9YJB4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

288004:AL038 RS15045
gene id: 288004:AL038_RS15045
uniprot id: A0A2N9YEI8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS11930
gene id: 288004:AL038_RS11930
uniprot id: A0A2N9YJC6
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

288004:AL038 RS13345
gene id: 288004:AL038_RS13345
uniprot id: A0A2N9YF99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

288004:AL038 RS13225
gene id: 288004:AL038_RS13225
uniprot id: A0A2N9YFQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

288004:AL038 RS15095
gene id: 288004:AL038_RS15095
uniprot id: A0A2N9YEH5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

288004:AL038 RS09055
gene id: 288004:AL038_RS09055
uniprot id: A0A2N9YHQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

288004:AL038 RS05835
gene id: 288004:AL038_RS05835
uniprot id: A0A2N9Y9Y0
names: Similarity
messages: Belongs to the peptidase S41A family.

288004:AL038 RS12605
gene id: 288004:AL038_RS12605
uniprot id: A0A2N9YFP8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

288004:AL038 RS08840
gene id: 288004:AL038_RS08840
uniprot id: A0A2N9YHU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

288004:AL038 RS05420
gene id: 288004:AL038_RS05420
uniprot id: A0A2N9YA58
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

288004:AL038 RS10220
gene id: 288004:AL038_RS10220
uniprot id: A0A2N9YGW7
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS15615
gene id: 288004:AL038_RS15615
uniprot id: A0A2N9YE83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

288004:AL038 RS02795
gene id: 288004:AL038_RS02795
uniprot id: A0A2N9YBF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

288004:AL038 RS04005
gene id: 288004:AL038_RS04005
uniprot id: A0A2N9YJ18
names: Similarity
messages: Belongs to the band 7/mec-2 family.

288004:AL038 RS06175
gene id: 288004:AL038_RS06175
uniprot id: A0A2N9YIV5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS02725
gene id: 288004:AL038_RS02725
uniprot id: A0A2N9YBG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

288004:AL038 RS14540
gene id: 288004:AL038_RS14540
uniprot id: A0A2N9YEV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

288004:AL038 RS12145
gene id: 288004:AL038_RS12145
uniprot id: A0A2N9YFV2
names: Similarity
messages: Belongs to the peptidase S13 family.

288004:AL038 RS16065
gene id: 288004:AL038_RS16065
uniprot id: A0A2N9YE16
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

288004:AL038 RS17665
gene id: 288004:AL038_RS17665
uniprot id: A0A2N9YD77
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

288004:AL038 RS14280
gene id: 288004:AL038_RS14280
uniprot id: A0A2N9YEU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS07610
gene id: 288004:AL038_RS07610
uniprot id: A0A2N9YI71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

288004:AL038 RS09130
gene id: 288004:AL038_RS09130
uniprot id: A0A2N9YHF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

288004:AL038 RS15465
gene id: 288004:AL038_RS15465
uniprot id: A0A2N9YE80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

288004:AL038 RS01750
gene id: 288004:AL038_RS01750
uniprot id: A0A2N9YBY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

288004:AL038 RS11120
gene id: 288004:AL038_RS11120
uniprot id: A0A2N9YGP2
names: Similarity
messages: Belongs to the SCO1/2 family.

288004:AL038 RS13975
gene id: 288004:AL038_RS13975
uniprot id: A0A2N9YEZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

288004:AL038 RS06025
gene id: 288004:AL038_RS06025
uniprot id: A0A2N9YJ07
names: Similarity
messages: Belongs to the RutC family.

288004:AL038 RS11440
gene id: 288004:AL038_RS11440
uniprot id: A0A2N9YGI3
names: Similarity
messages: Belongs to the RecJ family.

288004:AL038 RS05930
gene id: 288004:AL038_RS05930
uniprot id: A0A2N9Y9W1
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS06205
gene id: 288004:AL038_RS06205
uniprot id: A0A2N9YIS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

288004:AL038 RS13865
gene id: 288004:AL038_RS13865
uniprot id: A0A2N9YFD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

288004:AL038 RS14400
gene id: 288004:AL038_RS14400
uniprot id: A0A2N9YES8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS07250
gene id: 288004:AL038_RS07250
uniprot id: A0A2N9YJ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

288004:AL038 RS00110
gene id: 288004:AL038_RS00110
uniprot id: A0A2N9YCT4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

288004:AL038 RS13740
gene id: 288004:AL038_RS13740
uniprot id: A0A2N9YF33
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

288004:AL038 RS07740
gene id: 288004:AL038_RS07740
uniprot id: A0A2N9YI43
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

288004:AL038 RS15525
gene id: 288004:AL038_RS15525
uniprot id: A0A2N9YEB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

288004:AL038 RS07795
gene id: 288004:AL038_RS07795
uniprot id: A0A2N9YIC1
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

288004:AL038 RS17230
gene id: 288004:AL038_RS17230
uniprot id: A0A2N9YDP0
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS08320
gene id: 288004:AL038_RS08320
uniprot id: A0A2N9YHS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

288004:AL038 RS10350
gene id: 288004:AL038_RS10350
uniprot id: A0A2N9YGQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

288004:AL038 RS10900
gene id: 288004:AL038_RS10900
uniprot id: A0A2N9YGI9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

288004:AL038 RS02275
gene id: 288004:AL038_RS02275
uniprot id: A0A2N9YBQ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

288004:AL038 RS04055
gene id: 288004:AL038_RS04055
uniprot id: A0A2N9YJ36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

288004:AL038 RS12530
gene id: 288004:AL038_RS12530
uniprot id: A0A2N9YFN6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

288004:AL038 RS03170
gene id: 288004:AL038_RS03170
uniprot id: A0A2N9YB92
names: Similarity
messages: Belongs to the LOG family.

288004:AL038 RS04515
gene id: 288004:AL038_RS04515
uniprot id: A0A2N9YAM9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS17725
gene id: 288004:AL038_RS17725
uniprot id: A0A2N9YD66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

288004:AL038 RS09155
gene id: 288004:AL038_RS09155
uniprot id: A0A2N9YHD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

288004:AL038 RS08305
gene id: 288004:AL038_RS08305
uniprot id: A0A2N9YI31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

288004:AL038 RS13400
gene id: 288004:AL038_RS13400
uniprot id: A0A2N9YFM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

288004:AL038 RS17785
gene id: 288004:AL038_RS17785
uniprot id: A0A2N9YD21
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

288004:AL038 RS09180
gene id: 288004:AL038_RS09180
uniprot id: A0A2N9YHP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

288004:AL038 RS15635
gene id: 288004:AL038_RS15635
uniprot id: A0A2N9YE64
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

288004:AL038 RS16745
gene id: 288004:AL038_RS16745
uniprot id: A0A2N9YDW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

288004:AL038 RS03860
gene id: 288004:AL038_RS03860
uniprot id: A0A2N9YAW6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

288004:AL038 RS16975
gene id: 288004:AL038_RS16975
uniprot id: A0A2N9YDF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

288004:AL038 RS14870
gene id: 288004:AL038_RS14870
uniprot id: A0A2N9YEK1
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

288004:AL038 RS13170
gene id: 288004:AL038_RS13170
uniprot id: A0A2N9YFQ8
names: Similarity
messages: Belongs to the peptidase U62 family.

288004:AL038 RS03925
gene id: 288004:AL038_RS03925
uniprot id: A0A2N9YAW3
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

288004:AL038 RS01010
gene id: 288004:AL038_RS01010
uniprot id: A0A2N9YCD1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

288004:AL038 RS12375
gene id: 288004:AL038_RS12375
uniprot id: A0A650GDX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

288004:AL038 RS13990
gene id: 288004:AL038_RS13990
uniprot id: A0A2N9YF82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

288004:AL038 RS02705
gene id: 288004:AL038_RS02705
uniprot id: A0A2N9YBN9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS13470
gene id: 288004:AL038_RS13470
uniprot id: A0A2N9YFI9
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

288004:AL038 RS05430
gene id: 288004:AL038_RS05430
uniprot id: A0A2N9YA49
names: Subcellular Location Annotation
messages: Cell inner membrane

288004:AL038 RS14025
gene id: 288004:AL038_RS14025
uniprot id: A0A2N9YFA4
names: Similarity
messages: Belongs to the peptidase M16 family.

288004:AL038 RS14235
gene id: 288004:AL038_RS14235
uniprot id: A0A2N9YEV9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

288004:AL038 RS05330
gene id: 288004:AL038_RS05330
uniprot id: A0A2N9YA66
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

288004:AL038 RS14285
gene id: 288004:AL038_RS14285
uniprot id: A0A2N9YET7
names: Similarity
messages: Belongs to the BolA/IbaG family.

288004:AL038 RS01530
gene id: 288004:AL038_RS01530
uniprot id: A0A2N9YC31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

288004:AL038 RS02040
gene id: 288004:AL038_RS02040
uniprot id: A0A2N9YBU6
names: Similarity
messages: Belongs to the histone deacetylase family.

288004:AL038 RS15575
gene id: 288004:AL038_RS15575
uniprot id: A0A2N9YE73
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS02310
gene id: 288004:AL038_RS02310
uniprot id: A0A2N9YBM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

288004:AL038 RS05590
gene id: 288004:AL038_RS05590
uniprot id: A0A2N9YA17
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

288004:AL038 RS11465
gene id: 288004:AL038_RS11465
uniprot id: A0A2N9YG62
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

288004:AL038 RS08775
gene id: 288004:AL038_RS08775
uniprot id: A0A2N9YHE7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

288004:AL038 RS12060
gene id: 288004:AL038_RS12060
uniprot id: A0A2N9YFV9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

288004:AL038 RS06660
gene id: 288004:AL038_RS06660
uniprot id: A0A2N9YIJ7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

288004:AL038 RS16440
gene id: 288004:AL038_RS16440
uniprot id: A0A2N9YDP9
names: Similarity
messages: Belongs to the ArsC family.

288004:AL038 RS02430
gene id: 288004:AL038_RS02430
uniprot id: A0A2N9YBM7
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

288004:AL038 RS09770
gene id: 288004:AL038_RS09770
uniprot id: A0A2N9YH36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

288004:AL038 RS08675
gene id: 288004:AL038_RS08675
uniprot id: A0A2N9YHM3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

288004:AL038 RS11170
gene id: 288004:AL038_RS11170
uniprot id: A0A2N9YH52
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS16825
gene id: 288004:AL038_RS16825
uniprot id: A0A2N9YDJ4
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

288004:AL038 RS05105
gene id: 288004:AL038_RS05105
uniprot id: A0A2N9YAD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

288004:AL038 RS10820
gene id: 288004:AL038_RS10820
uniprot id: A0A2N9YGT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

288004:AL038 RS12110
gene id: 288004:AL038_RS12110
uniprot id: A0A2N9YGP1
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS02930
gene id: 288004:AL038_RS02930
uniprot id: A0A2N9YBE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

288004:AL038 RS11760
gene id: 288004:AL038_RS11760
uniprot id: A0A2N9YGC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

288004:AL038 RS11260
gene id: 288004:AL038_RS11260
uniprot id: A0A2N9YG98
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS12255
gene id: 288004:AL038_RS12255
uniprot id: A0A2N9YFT5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

288004:AL038 RS07690
gene id: 288004:AL038_RS07690
uniprot id: A0A2N9YI09
names: Similarity
messages: Belongs to the ClpA/ClpB family.

288004:AL038 RS14115
gene id: 288004:AL038_RS14115
uniprot id: A0A2N9YEX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

288004:AL038 RS17575
gene id: 288004:AL038_RS17575
uniprot id: A0A2N9YD78
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

288004:AL038 RS10205
gene id: 288004:AL038_RS10205
uniprot id: A0A2N9YHL9
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

288004:AL038 RS10050
gene id: 288004:AL038_RS10050
uniprot id: A0A2N9YH76
names: Similarity
messages: Belongs to the thioredoxin family.

288004:AL038 RS04965
gene id: 288004:AL038_RS04965
uniprot id: A0A2N9YAB8
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

288004:AL038 RS14360
gene id: 288004:AL038_RS14360
uniprot id: A0A2N9YES3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

288004:AL038 RS16575
gene id: 288004:AL038_RS16575
uniprot id: A0A2N9YDR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

288004:AL038 RS17945
gene id: 288004:AL038_RS17945
uniprot id: A0A2N9YD32
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

288004:AL038 RS05690
gene id: 288004:AL038_RS05690
uniprot id: A0A2N9YA14
names: Similarity
messages: Belongs to the MipA/OmpV family.

288004:AL038 RS03595
gene id: 288004:AL038_RS03595
uniprot id: A0A2N9YJ03
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

288004:AL038 RS13955
gene id: 288004:AL038_RS13955
uniprot id: A0A2N9YEZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

288004:AL038 RS06550
gene id: 288004:AL038_RS06550
uniprot id: A0A2N9YIL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

288004:AL038 RS11215
gene id: 288004:AL038_RS11215
uniprot id: A0A2N9YG86
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

288004:AL038 RS00935
gene id: 288004:AL038_RS00935
uniprot id: A0A2N9YCI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

288004:AL038 RS01640
gene id: 288004:AL038_RS01640
uniprot id: A0A2N9YC73
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS01295
gene id: 288004:AL038_RS01295
uniprot id: A0A2N9YC52
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

288004:AL038 RS13880
gene id: 288004:AL038_RS13880
uniprot id: A0A2N9YF62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

288004:AL038 RS10710
gene id: 288004:AL038_RS10710
uniprot id: A0A2N9YGV4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS04885
gene id: 288004:AL038_RS04885
uniprot id: A0A2N9YAF6
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS01575
gene id: 288004:AL038_RS01575
uniprot id: A0A2N9YC08
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS09685
gene id: 288004:AL038_RS09685
uniprot id: A0A2N9YHW5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS03160
gene id: 288004:AL038_RS03160
uniprot id: A0A2N9YB84
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

288004:AL038 RS10730
gene id: 288004:AL038_RS10730
uniprot id: A0A2N9YGW1
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS01795
gene id: 288004:AL038_RS01795
uniprot id: A0A2N9YBY6
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS06305
gene id: 288004:AL038_RS06305
uniprot id: A0A2N9YIQ8
names: Similarity
messages: Belongs to the agmatine deiminase family.

288004:AL038 RS17515
gene id: 288004:AL038_RS17515
uniprot id: A0A2N9YD92
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

288004:AL038 RS02225
gene id: 288004:AL038_RS02225
uniprot id: A0A2N9YBR0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

288004:AL038 RS04430
gene id: 288004:AL038_RS04430
uniprot id: A0A2N9YAP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

288004:AL038 RS18060
gene id: 288004:AL038_RS18060
uniprot id: A0A2N9YCY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

288004:AL038 RS09965
gene id: 288004:AL038_RS09965
uniprot id: A0A2N9YGX7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

288004:AL038 RS02660
gene id: 288004:AL038_RS02660
uniprot id: A0A2N9YBJ2
names: Similarity
messages: Belongs to the aspartokinase family.

288004:AL038 RS16740
gene id: 288004:AL038_RS16740
uniprot id: A0A2N9YDN5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS03900
gene id: 288004:AL038_RS03900
uniprot id: A0A2N9YAW2
names: Similarity
messages: Belongs to the peptidase U62 family.

288004:AL038 RS10240
gene id: 288004:AL038_RS10240
uniprot id: A0A2N9YH31
names: Similarity
messages: Belongs to the hemerythrin family.

288004:AL038 RS09680
gene id: 288004:AL038_RS09680
uniprot id: A0A2N9YH29
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

288004:AL038 RS14550
gene id: 288004:AL038_RS14550
uniprot id: A0A2N9YER1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

288004:AL038 RS06930
gene id: 288004:AL038_RS06930
uniprot id: A0A2N9YIB4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

288004:AL038 RS06540
gene id: 288004:AL038_RS06540
uniprot id: A0A2N9YIP8
names: Similarity
messages: Belongs to the hemerythrin family.

288004:AL038 RS01515
gene id: 288004:AL038_RS01515
uniprot id: A0A2N9YC67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

288004:AL038 RS10370
gene id: 288004:AL038_RS10370
uniprot id: A0A2N9YHJ0
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

288004:AL038 RS05375
gene id: 288004:AL038_RS05375
uniprot id: A0A2N9YA67
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

288004:AL038 RS13835
gene id: 288004:AL038_RS13835
uniprot id: A0A2N9YF40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

288004:AL038 RS17925
gene id: 288004:AL038_RS17925
uniprot id: A0A2N9YD06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

288004:AL038 RS07045
gene id: 288004:AL038_RS07045
uniprot id: A0A2N9YI99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

288004:AL038 RS03080
gene id: 288004:AL038_RS03080
uniprot id: A0A2N9YBB4
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

288004:AL038 RS00275
gene id: 288004:AL038_RS00275
uniprot id: A0A2N9YCQ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

288004:AL038 RS11460
gene id: 288004:AL038_RS11460
uniprot id: A0A2N9YFZ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

288004:AL038 RS05525
gene id: 288004:AL038_RS05525
uniprot id: A0A2N9YA41
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

288004:AL038 RS07310
gene id: 288004:AL038_RS07310
uniprot id: A0A2N9YI98
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

288004:AL038 RS03495
gene id: 288004:AL038_RS03495
uniprot id: A0A2N9YB29
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS12980
gene id: 288004:AL038_RS12980
uniprot id: A0A2N9YJH3
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

288004:AL038 RS10520
gene id: 288004:AL038_RS10520
uniprot id: A0A2N9YGL1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

288004:AL038 RS09240
gene id: 288004:AL038_RS09240
uniprot id: A0A2N9YHD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

288004:AL038 RS05790
gene id: 288004:AL038_RS05790
uniprot id: A0A2N9Y9Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

288004:AL038 RS03350
gene id: 288004:AL038_RS03350
uniprot id: A0A2N9YB83
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

288004:AL038 RS03720
gene id: 288004:AL038_RS03720
uniprot id: A0A2N9YJ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

288004:AL038 RS17920
gene id: 288004:AL038_RS17920
uniprot id: A0A2N9YD15
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS07990
gene id: 288004:AL038_RS07990
uniprot id: A0A2N9YI17
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

288004:AL038 RS13065
gene id: 288004:AL038_RS13065
uniprot id: A0A2N9YFG9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

288004:AL038 RS13980
gene id: 288004:AL038_RS13980
uniprot id: A0A2N9YEZ3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

288004:AL038 RS13845
gene id: 288004:AL038_RS13845
uniprot id: A0A2N9YF29
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS10420
gene id: 288004:AL038_RS10420
uniprot id: A0A2N9YH02
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

288004:AL038 RS17895
gene id: 288004:AL038_RS17895
uniprot id: A0A2N9YD25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

288004:AL038 RS13925
gene id: 288004:AL038_RS13925
uniprot id: A0A2N9YF02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

288004:AL038 RS08445
gene id: 288004:AL038_RS08445
uniprot id: A0A2N9YI14
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS04865
gene id: 288004:AL038_RS04865
uniprot id: A0A2N9YAF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

288004:AL038 RS00750
gene id: 288004:AL038_RS00750
uniprot id: A0A2N9YCI2
names: Similarity
messages: Belongs to the MEMO1 family.

288004:AL038 RS16165
gene id: 288004:AL038_RS16165
uniprot id: A0A2N9YDW4
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS15820
gene id: 288004:AL038_RS15820
uniprot id: A0A2N9YEB5
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS07790
gene id: 288004:AL038_RS07790
uniprot id: A0A2N9YI32
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

288004:AL038 RS01415
gene id: 288004:AL038_RS01415
uniprot id: A0A2N9YC59
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

288004:AL038 RS13030
gene id: 288004:AL038_RS13030
uniprot id: A0A2N9YFI1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

288004:AL038 RS04135
gene id: 288004:AL038_RS04135
uniprot id: A0A2N9YAS3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

288004:AL038 RS15085
gene id: 288004:AL038_RS15085
uniprot id: A0A2N9YEJ3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

288004:AL038 RS14140
gene id: 288004:AL038_RS14140
uniprot id: A0A2N9YEW6
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

288004:AL038 RS15265
gene id: 288004:AL038_RS15265
uniprot id: A0A2N9YEE6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS16680
gene id: 288004:AL038_RS16680
uniprot id: A0A2N9YE01
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS07895
gene id: 288004:AL038_RS07895
uniprot id: A0A2N9YI94
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

288004:AL038 RS09060
gene id: 288004:AL038_RS09060
uniprot id: A0A2N9YHB8
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

288004:AL038 RS02365
gene id: 288004:AL038_RS02365
uniprot id: A0A2N9YBT4
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

288004:AL038 RS09260
gene id: 288004:AL038_RS09260
uniprot id: A0A2N9YHB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

288004:AL038 RS14860
gene id: 288004:AL038_RS14860
uniprot id: A0A2N9YEL2
names: Similarity
messages: Belongs to the YciI family.

288004:AL038 RS08755
gene id: 288004:AL038_RS08755
uniprot id: A0A2N9YHM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

288004:AL038 RS10925
gene id: 288004:AL038_RS10925
uniprot id: A0A2N9YGG8
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS03095
gene id: 288004:AL038_RS03095
uniprot id: A0A2N9YBB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

288004:AL038 RS11680
gene id: 288004:AL038_RS11680
uniprot id: A0A2N9YFW3
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

288004:AL038 RS08195
gene id: 288004:AL038_RS08195
uniprot id: A0A2N9YHU7
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

288004:AL038 RS17590
gene id: 288004:AL038_RS17590
uniprot id: A0A2N9YD44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

288004:AL038 RS07015
gene id: 288004:AL038_RS07015
uniprot id: A0A2N9YIF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

288004:AL038 RS06805
gene id: 288004:AL038_RS06805
uniprot id: A0A2N9YIL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

288004:AL038 RS10115
gene id: 288004:AL038_RS10115
uniprot id: A0A2N9YGS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

288004:AL038 RS12915
gene id: 288004:AL038_RS12915
uniprot id: A0A2N9YFI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

288004:AL038 RS11195
gene id: 288004:AL038_RS11195
uniprot id: A0A2N9YG41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

288004:AL038 RS03085
gene id: 288004:AL038_RS03085
uniprot id: A0A2N9YBB5
names: Similarity
messages: Belongs to the phosphoribulokinase family.

288004:AL038 RS05580
gene id: 288004:AL038_RS05580
uniprot id: A0A2N9YA30
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS07750
gene id: 288004:AL038_RS07750
uniprot id: A0A2N9YI02
names: Similarity
messages: Belongs to the AlaDH/PNT family.

288004:AL038 RS14380
gene id: 288004:AL038_RS14380
uniprot id: A0A2N9YET5
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS04850
gene id: 288004:AL038_RS04850
uniprot id: A0A2N9YAE8
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

288004:AL038 RS11365
gene id: 288004:AL038_RS11365
uniprot id: A0A2N9YG81
names: Similarity
messages: Belongs to the CutA family.

288004:AL038 RS17095
gene id: 288004:AL038_RS17095
uniprot id: A0A2N9YDD7
names: Similarity
messages: Belongs to the PhoH family.

288004:AL038 RS13140
gene id: 288004:AL038_RS13140
uniprot id: A0A2N9YG73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

288004:AL038 RS10485
gene id: 288004:AL038_RS10485
uniprot id: A0A2N9YGZ2
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS06860
gene id: 288004:AL038_RS06860
uniprot id: A0A2N9YIF4
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

288004:AL038 RS06555
gene id: 288004:AL038_RS06555
uniprot id: A0A2N9YIN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

288004:AL038 RS03225
gene id: 288004:AL038_RS03225
uniprot id: A0A2N9YB71
names: Subcellular Location Annotation
messages: Cell inner membrane

288004:AL038 RS14220
gene id: 288004:AL038_RS14220
uniprot id: A0A2N9YEV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

288004:AL038 RS03835
gene id: 288004:AL038_RS03835
uniprot id: A0A2N9YAW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

288004:AL038 RS08830
gene id: 288004:AL038_RS08830
uniprot id: A0A2N9YHD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS14210
gene id: 288004:AL038_RS14210
uniprot id: A0A2N9YEX0
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS15305
gene id: 288004:AL038_RS15305
uniprot id: A0A2N9YEA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

288004:AL038 RS02590
gene id: 288004:AL038_RS02590
uniprot id: A0A2N9YBK8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

288004:AL038 RS08700
gene id: 288004:AL038_RS08700
uniprot id: A0A2N9YHQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

288004:AL038 RS14205
gene id: 288004:AL038_RS14205
uniprot id: A0A2N9YF25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

288004:AL038 RS18100
gene id: 288004:AL038_RS18100
uniprot id: A0A2N9YCX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

288004:AL038 RS08680
gene id: 288004:AL038_RS08680
uniprot id: A0A2N9YIE3
names: Subcellular Location Annotation
messages: Cytoplasm

288004:AL038 RS04820
gene id: 288004:AL038_RS04820
uniprot id: A0A2N9YAE3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

288004:AL038 RS14215
gene id: 288004:AL038_RS14215
uniprot id: A0A2N9YEU9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

288004:AL038 RS10035
gene id: 288004:AL038_RS10035
uniprot id: A0A2N9YGU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

288004:AL038 RS15810
gene id: 288004:AL038_RS15810
uniprot id: A0A2N9YE21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SDHAF4 family.
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

288004:AL038 RS08140
gene id: 288004:AL038_RS08140
uniprot id: A0A2N9YHV7
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

288004:AL038 RS04305
gene id: 288004:AL038_RS04305
uniprot id: A0A2N9YAP1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

288004:AL038 RS00570
gene id: 288004:AL038_RS00570
uniprot id: A0A2N9YCL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS03840
gene id: 288004:AL038_RS03840
uniprot id: A0A2N9YAX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

288004:AL038 RS11090
gene id: 288004:AL038_RS11090
uniprot id: A0A2N9YGA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

288004:AL038 RS16535
gene id: 288004:AL038_RS16535
uniprot id: A0A2N9YDP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

288004:AL038 RS03525
gene id: 288004:AL038_RS03525
uniprot id: A0A2N9YB51
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

288004:AL038 RS15075
gene id: 288004:AL038_RS15075
uniprot id: A0A2N9YEE2
names: Similarity
messages: Belongs to the fabD family.

288004:AL038 RS14640
gene id: 288004:AL038_RS14640
uniprot id: A0A2N9YEL4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

288004:AL038 RS05360
gene id: 288004:AL038_RS05360
uniprot id: A0A2N9YA61
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS11355
gene id: 288004:AL038_RS11355
uniprot id: A0A2N9YG71
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

288004:AL038 RS08895
gene id: 288004:AL038_RS08895
uniprot id: A0A2N9YHH9
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

288004:AL038 RS09050
gene id: 288004:AL038_RS09050
uniprot id: A0A2N9YHF0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

288004:AL038 RS06060
gene id: 288004:AL038_RS06060
uniprot id: A0A2N9YJL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

288004:AL038 RS14080
gene id: 288004:AL038_RS14080
uniprot id: A0A2N9YEX9
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

288004:AL038 RS04670
gene id: 288004:AL038_RS04670
uniprot id: A0A2N9YAI6
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

288004:AL038 RS12475
gene id: 288004:AL038_RS12475
uniprot id: A0A2N9YG05
names: Similarity
messages: Belongs to the PspA/IM30 family.

288004:AL038 RS05705
gene id: 288004:AL038_RS05705
uniprot id: A0A2N9YA00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

288004:AL038 RS13415
gene id: 288004:AL038_RS13415
uniprot id: A0A2N9YFF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

288004:AL038 RS00960
gene id: 288004:AL038_RS00960
uniprot id: A0A2N9YJ55
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

288004:AL038 RS11530
gene id: 288004:AL038_RS11530
uniprot id: A0A2N9YGF7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

288004:AL038 RS10085
gene id: 288004:AL038_RS10085
uniprot id: A0A2N9YH60
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

288004:AL038 RS07330
gene id: 288004:AL038_RS07330
uniprot id: A0A2N9YID5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

288004:AL038 RS02915
gene id: 288004:AL038_RS02915
uniprot id: A0A2N9YBF1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

288004:AL038 RS04480
gene id: 288004:AL038_RS04480
uniprot id: A0A2N9YAM0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

288004:AL038 RS04320
gene id: 288004:AL038_RS04320
uniprot id: A0A2N9YAQ2
names: Similarity
messages: Belongs to the fructosamine kinase family.

288004:AL038 RS13725
gene id: 288004:AL038_RS13725
uniprot id: A0A2N9YF50
names: Similarity
messages: Belongs to the phosphohexose mutase family.

288004:AL038 RS03640
gene id: 288004:AL038_RS03640
uniprot id: A0A2N9YB35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

288004:AL038 RS01345
gene id: 288004:AL038_RS01345
uniprot id: A0A2N9YCA5
names: Similarity
messages: Belongs to the TmoD/XamoD family.

288004:AL038 RS15625
gene id: 288004:AL038_RS15625
uniprot id: A0A2N9YE59
names: Similarity
messages: Belongs to the HypE family.

288004:AL038 RS02960
gene id: 288004:AL038_RS02960
uniprot id: A0A2N9YBC8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

288004:AL038 RS02045
gene id: 288004:AL038_RS02045
uniprot id: A0A2N9YBX2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

288004:AL038 RS09935
gene id: 288004:AL038_RS09935
uniprot id: A0A2N9YH99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

288004:AL038 RS16015
gene id: 288004:AL038_RS16015
uniprot id: A0A2N9YDY9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

288004:AL038 RS03330
gene id: 288004:AL038_RS03330
uniprot id: A0A2N9YB49
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

288004:AL038 RS10075
gene id: 288004:AL038_RS10075
uniprot id: A0A2N9YGQ0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

288004:AL038 RS01165
gene id: 288004:AL038_RS01165
uniprot id: A0A2N9YCE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

288004:AL038 RS07185
gene id: 288004:AL038_RS07185
uniprot id: A0A2N9YJ67
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

288004:AL038 RS01695
gene id: 288004:AL038_RS01695
uniprot id: A0A2N9YC34
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

288004:AL038 RS07130
gene id: 288004:AL038_RS07130
uniprot id: A0A2N9YJ78
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

288004:AL038 RS08565
gene id: 288004:AL038_RS08565
uniprot id: A0A2N9YIG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

288004:AL038 RS10635
gene id: 288004:AL038_RS10635
uniprot id: A0A2N9YGE5
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

288004:AL038 RS05665
gene id: 288004:AL038_RS05665
uniprot id: A0A2N9YA04
names: Similarity
messages: Belongs to the FeoA family.

288004:AL038 RS13515
gene id: 288004:AL038_RS13515
uniprot id: A0A2N9YF94
names: Similarity
messages: Belongs to the XseB family.

288004:AL038 RS14100
gene id: 288004:AL038_RS14100
uniprot id: A0A2N9YF58
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

288004:AL038 RS04510
gene id: 288004:AL038_RS04510
uniprot id: A0A2N9YAL7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

288004:AL038 RS13970
gene id: 288004:AL038_RS13970
uniprot id: A0A2N9YFB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

288004:AL038 RS08940
gene id: 288004:AL038_RS08940
uniprot id: A0A2N9YHB5
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

288004:AL038 RS17615
gene id: 288004:AL038_RS17615
uniprot id: A0A2N9YD82
names: Subcellular Location Annotation
messages: Mitochondrion

288004:AL038 RS17685
gene id: 288004:AL038_RS17685
uniprot id: A0A2N9YD37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

288004:AL038 RS16005
gene id: 288004:AL038_RS16005
uniprot id: A0A2N9YEC3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

288004:AL038 RS11030
gene id: 288004:AL038_RS11030
uniprot id: A0A650GDW7
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS13475
gene id: 288004:AL038_RS13475
uniprot id: A0A2N9YJG5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

288004:AL038 RS06380
gene id: 288004:AL038_RS06380
uniprot id: A0A2N9YIP7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

288004:AL038 RS02165
gene id: 288004:AL038_RS02165
uniprot id: A0A2N9YBZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

288004:AL038 RS00785
gene id: 288004:AL038_RS00785
uniprot id: A0A2N9YCL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

288004:AL038 RS11785
gene id: 288004:AL038_RS11785
uniprot id: A0A2N9YG08
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

288004:AL038 RS10265
gene id: 288004:AL038_RS10265
uniprot id: A0A2N9YGT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

288004:AL038 RS10555
gene id: 288004:AL038_RS10555
uniprot id: A0A2N9YGZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-2 integral membrane protein family. Lipooligosaccharide exporter (TC 3.A.1.102) subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit encodes the transporter.
messages: The complex is composed of two ATP-binding proteins (NodI) and two transmembrane proteins (NodJ).

288004:AL038 RS01065
gene id: 288004:AL038_RS01065
uniprot id: A0A2N9YCC3
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

288004:AL038 RS07565
gene id: 288004:AL038_RS07565
uniprot id: A0A2N9YI18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

288004:AL038 RS04490
gene id: 288004:AL038_RS04490
uniprot id: A0A2N9YAK2
names: Similarity
messages: Belongs to the UPF0250 family.

288004:AL038 RS09195
gene id: 288004:AL038_RS09195
uniprot id: A0A2N9YH96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

288004:AL038 RS02000
gene id: 288004:AL038_RS02000
uniprot id: A0A2N9YBT9
names: Similarity
messages: Belongs to the peptidase S8 family.

288004:AL038 RS00940
gene id: 288004:AL038_RS00940
uniprot id: A0A2N9YCE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

288004:AL038 RS08915
gene id: 288004:AL038_RS08915
uniprot id: A0A2N9YIB8
names: Similarity
messages: Belongs to the peptidase M4 family.

288004:AL038 RS03650
gene id: 288004:AL038_RS03650
uniprot id: A0A2N9YB44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

288004:AL038 RS14105
gene id: 288004:AL038_RS14105
uniprot id: A0A2N9YEZ2
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

288004:AL038 RS11040
gene id: 288004:AL038_RS11040
uniprot id: A0A2N9YGB8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

288004:AL038 RS15040
gene id: 288004:AL038_RS15040
uniprot id: A0A2N9YEP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

288004:AL038 RS16235
gene id: 288004:AL038_RS16235
uniprot id: A0A2N9YDV1
names: Subcellular Location Annotation
messages: Cytoplasm

288004:AL038 RS11425
gene id: 288004:AL038_RS11425
uniprot id: A0A2N9YG48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

288004:AL038 RS09230
gene id: 288004:AL038_RS09230
uniprot id: A0A2N9YI48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

288004:AL038 RS03685
gene id: 288004:AL038_RS03685
uniprot id: A0A2N9YAZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

288004:AL038 RS06440
gene id: 288004:AL038_RS06440
uniprot id: A0A2N9YIQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

288004:AL038 RS08630
gene id: 288004:AL038_RS08630
uniprot id: A0A2N9YHP4
names: Similarity
messages: Belongs to the universal stress protein A family.

288004:AL038 RS08230
gene id: 288004:AL038_RS08230
uniprot id: A0A2N9YHT9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

288004:AL038 RS13820
gene id: 288004:AL038_RS13820
uniprot id: A0A2N9YF69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

288004:AL038 RS00395
gene id: 288004:AL038_RS00395
uniprot id: A0A2N9YCS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

288004:AL038 RS15080
gene id: 288004:AL038_RS15080
uniprot id: A0A2N9YEF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

288004:AL038 RS08245
gene id: 288004:AL038_RS08245
uniprot id: A0A2N9YHQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

288004:AL038 RS15605
gene id: 288004:AL038_RS15605
uniprot id: A0A2N9YEA9
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

288004:AL038 RS17470
gene id: 288004:AL038_RS17470
uniprot id: A0A2N9YD61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

288004:AL038 RS16885
gene id: 288004:AL038_RS16885
uniprot id: A0A2N9YDW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS18395
gene id: 288004:AL038_RS18395
uniprot id: A0A2N9YC47
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

288004:AL038 RS15290
gene id: 288004:AL038_RS15290
uniprot id: A0A2N9YEC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

288004:AL038 RS16070
gene id: 288004:AL038_RS16070
uniprot id: A0A2N9YE72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

288004:AL038 RS06180
gene id: 288004:AL038_RS06180
uniprot id: A0A2N9YIY0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS15975
gene id: 288004:AL038_RS15975
uniprot id: A0A2N9YE91
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

288004:AL038 RS11150
gene id: 288004:AL038_RS11150
uniprot id: A0A2N9YGM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

288004:AL038 RS07775
gene id: 288004:AL038_RS07775
uniprot id: A0A2N9YI69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

288004:AL038 RS01680
gene id: 288004:AL038_RS01680
uniprot id: A0A2N9YC44
names: Subcellular Location Annotation
messages: Cytoplasm

288004:AL038 RS03440
gene id: 288004:AL038_RS03440
uniprot id: A0A2N9YBA8
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

288004:AL038 RS07700
gene id: 288004:AL038_RS07700
uniprot id: A0A2N9YIX7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

288004:AL038 RS13850
gene id: 288004:AL038_RS13850
uniprot id: A0A2N9YF31
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

288004:AL038 RS14940
gene id: 288004:AL038_RS14940
uniprot id: A0A2N9YEW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

288004:AL038 RS15210
gene id: 288004:AL038_RS15210
uniprot id: A0A2N9YEF9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

288004:AL038 RS10945
gene id: 288004:AL038_RS10945
uniprot id: A0A2N9YGS4
names: Similarity
messages: Belongs to the UPF0758 family.

288004:AL038 RS10985
gene id: 288004:AL038_RS10985
uniprot id: A0A2N9YGQ4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

288004:AL038 RS09065
gene id: 288004:AL038_RS09065
uniprot id: A0A2N9YHF2
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

288004:AL038 RS04815
gene id: 288004:AL038_RS04815
uniprot id: A0A2N9YAH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

288004:AL038 RS15415
gene id: 288004:AL038_RS15415
uniprot id: A0A2N9YE88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

288004:AL038 RS14890
gene id: 288004:AL038_RS14890
uniprot id: A0A2N9YEM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

288004:AL038 RS09140
gene id: 288004:AL038_RS09140
uniprot id: A0A2N9YHH0
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

288004:AL038 RS09120
gene id: 288004:AL038_RS09120
uniprot id: A0A2N9YI76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

288004:AL038 RS15620
gene id: 288004:AL038_RS15620
uniprot id: A0A2N9YE57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

288004:AL038 RS08885
gene id: 288004:AL038_RS08885
uniprot id: A0A2N9YHF6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

288004:AL038 RS00890
gene id: 288004:AL038_RS00890
uniprot id: A0A2N9YCK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

288004:AL038 RS11305
gene id: 288004:AL038_RS11305
uniprot id: A0A2N9YG23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS09865
gene id: 288004:AL038_RS09865
uniprot id: A0A2N9YGX8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

288004:AL038 RS09255
gene id: 288004:AL038_RS09255
uniprot id: A0A2N9YH54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

288004:AL038 RS01025
gene id: 288004:AL038_RS01025
uniprot id: A0A2N9YCD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

288004:AL038 RS03910
gene id: 288004:AL038_RS03910
uniprot id: A0A2N9YAY2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

288004:AL038 RS09320
gene id: 288004:AL038_RS09320
uniprot id: A0A2N9YI30
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

288004:AL038 RS17400
gene id: 288004:AL038_RS17400
uniprot id: A0A2N9YD93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

288004:AL038 RS06690
gene id: 288004:AL038_RS06690
uniprot id: A0A2N9YIN8
names: Similarity
messages: Belongs to the peptidase A31 family.

288004:AL038 RS17250
gene id: 288004:AL038_RS17250
uniprot id: A0A2N9YDN3
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

288004:AL038 RS17730
gene id: 288004:AL038_RS17730
uniprot id: A0A2N9YD24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

288004:AL038 RS11100
gene id: 288004:AL038_RS11100
uniprot id: A0A2N9YJS1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

288004:AL038 RS14185
gene id: 288004:AL038_RS14185
uniprot id: A0A2N9YF81
names: Similarity
messages: Belongs to the SCO1/2 family.

288004:AL038 RS08180
gene id: 288004:AL038_RS08180
uniprot id: A0A2N9YI47
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

288004:AL038 RS09250
gene id: 288004:AL038_RS09250
uniprot id: A0A2N9YH87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

288004:AL038 RS01180
gene id: 288004:AL038_RS01180
uniprot id: A0A2N9YCA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

288004:AL038 RS16705
gene id: 288004:AL038_RS16705
uniprot id: A0A2N9YDK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

288004:AL038 RS00740
gene id: 288004:AL038_RS00740
uniprot id: A0A2N9YCJ7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

288004:AL038 RS01975
gene id: 288004:AL038_RS01975
uniprot id: A0A2N9YBU9
names: Similarity
messages: Belongs to the selenium-binding protein family.

288004:AL038 RS08025
gene id: 288004:AL038_RS08025
uniprot id: A0A2N9YHX5
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS15320
gene id: 288004:AL038_RS15320
uniprot id: A0A2N9YEK2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

288004:AL038 RS17680
gene id: 288004:AL038_RS17680
uniprot id: A0A2N9YD33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

288004:AL038 RS01135
gene id: 288004:AL038_RS01135
uniprot id: A0A2N9YC97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

288004:AL038 RS08740
gene id: 288004:AL038_RS08740
uniprot id: A0A2N9YID4
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS08340
gene id: 288004:AL038_RS08340
uniprot id: A0A2N9YHU5
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

288004:AL038 RS16045
gene id: 288004:AL038_RS16045
uniprot id: A0A2N9YDY3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS03375
gene id: 288004:AL038_RS03375
uniprot id: A0A2N9YBB7
names: Similarity
messages: Belongs to the intimin/invasin family.

288004:AL038 RS05100
gene id: 288004:AL038_RS05100
uniprot id: A0A2N9YAB5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

288004:AL038 RS04225
gene id: 288004:AL038_RS04225
uniprot id: A0A2N9YAQ3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

288004:AL038 RS15295
gene id: 288004:AL038_RS15295
uniprot id: A0A2N9YEQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

288004:AL038 RS10355
gene id: 288004:AL038_RS10355
uniprot id: A0A2N9YH11
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

288004:AL038 RS06770
gene id: 288004:AL038_RS06770
uniprot id: A0A2N9YIL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

288004:AL038 RS12535
gene id: 288004:AL038_RS12535
uniprot id: A0A2N9YFQ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

288004:AL038 RS17375
gene id: 288004:AL038_RS17375
uniprot id: A0A2N9YDA4
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

288004:AL038 RS04675
gene id: 288004:AL038_RS04675
uniprot id: A0A2N9YAI8
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

288004:AL038 RS01715
gene id: 288004:AL038_RS01715
uniprot id: A0A2N9YBZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

288004:AL038 RS08390
gene id: 288004:AL038_RS08390
uniprot id: A0A2N9YI24
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

288004:AL038 RS13965
gene id: 288004:AL038_RS13965
uniprot id: A0A650GD91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

288004:AL038 RS13120
gene id: 288004:AL038_RS13120
uniprot id: A0A2N9YFG0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

288004:AL038 RS02805
gene id: 288004:AL038_RS02805
uniprot id: A0A2N9YBF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

288004:AL038 RS17135
gene id: 288004:AL038_RS17135
uniprot id: A0A2N9YDB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

288004:AL038 RS06575
gene id: 288004:AL038_RS06575
uniprot id: A0A2N9YIQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

288004:AL038 RS04470
gene id: 288004:AL038_RS04470
uniprot id: A0A2N9YAL2
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

288004:AL038 RS01170
gene id: 288004:AL038_RS01170
uniprot id: A0A2N9YCA1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

288004:AL038 RS17835
gene id: 288004:AL038_RS17835
uniprot id: A0A2N9YDC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

288004:AL038 RS01050
gene id: 288004:AL038_RS01050
uniprot id: A0A2N9YCF2
names: Similarity
messages: Belongs to the YkuD family.

288004:AL038 RS02735
gene id: 288004:AL038_RS02735
uniprot id: A0A2N9YBG2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS05620
gene id: 288004:AL038_RS05620
uniprot id: A0A2N9YA16
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

288004:AL038 RS11140
gene id: 288004:AL038_RS11140
uniprot id: A0A2N9YG49
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

288004:AL038 RS04895
gene id: 288004:AL038_RS04895
uniprot id: A0A2N9YAF4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

288004:AL038 RS07745
gene id: 288004:AL038_RS07745
uniprot id: A0A2N9YID1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

288004:AL038 RS14315
gene id: 288004:AL038_RS14315
uniprot id: A0A2N9YEY9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

288004:AL038 RS00695
gene id: 288004:AL038_RS00695
uniprot id: A0A2N9YCI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

288004:AL038 RS01850
gene id: 288004:AL038_RS01850
uniprot id: A0A2N9YC24
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

288004:AL038 RS00295
gene id: 288004:AL038_RS00295
uniprot id: A0A2N9YCS6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

288004:AL038 RS07695
gene id: 288004:AL038_RS07695
uniprot id: A0A2N9YI33
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

288004:AL038 RS03140
gene id: 288004:AL038_RS03140
uniprot id: A0A2N9YBA6
names: Similarity
messages: Belongs to the UPF0102 family.

288004:AL038 RS13520
gene id: 288004:AL038_RS13520
uniprot id: A0A2N9YFD2
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS00880
gene id: 288004:AL038_RS00880
uniprot id: A0A2N9YCJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

288004:AL038 RS06520
gene id: 288004:AL038_RS06520
uniprot id: A0A2N9YIP5
names: Similarity
messages: Belongs to the HesB/IscA family.

288004:AL038 RS06365
gene id: 288004:AL038_RS06365
uniprot id: A0A2N9YIN3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

288004:AL038 RS02895
gene id: 288004:AL038_RS02895
uniprot id: A0A2N9YBD6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

288004:AL038 RS15550
gene id: 288004:AL038_RS15550
uniprot id: A0A2N9YE58
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

288004:AL038 RS12745
gene id: 288004:AL038_RS12745
uniprot id: A0A2N9YFL2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

288004:AL038 RS08855
gene id: 288004:AL038_RS08855
uniprot id: A0A2N9YIC3
names: Similarity
messages: Belongs to the peptidase C40 family.

288004:AL038 RS10980
gene id: 288004:AL038_RS10980
uniprot id: A0A2N9YGF2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

288004:AL038 RS01520
gene id: 288004:AL038_RS01520
uniprot id: A0A2N9YC18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

288004:AL038 RS08210
gene id: 288004:AL038_RS08210
uniprot id: A0A2N9YHW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

288004:AL038 RS03730
gene id: 288004:AL038_RS03730
uniprot id: A0A2N9YAY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

288004:AL038 RS04090
gene id: 288004:AL038_RS04090
uniprot id: A0A2N9YAS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

288004:AL038 RS14515
gene id: 288004:AL038_RS14515
uniprot id: A0A2N9YF23
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

288004:AL038 RS05240
gene id: 288004:AL038_RS05240
uniprot id: A0A2N9YA85
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

288004:AL038 RS10750
gene id: 288004:AL038_RS10750
uniprot id: A0A2N9YGC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FTR family.
messages: Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT).
messages: Cytoplasm
messages: Homotetramer.

288004:AL038 RS12685
gene id: 288004:AL038_RS12685
uniprot id: A0A2N9YFL3
names: Similarity
messages: Belongs to the peptidase M16 family.

288004:AL038 RS17750
gene id: 288004:AL038_RS17750
uniprot id: A0A2N9YDE8
names: Similarity
messages: Belongs to the TrpC family.

288004:AL038 RS12425
gene id: 288004:AL038_RS12425
uniprot id: A0A2N9YFQ4
names: Similarity
messages: Belongs to the NifZ family.

288004:AL038 RS10655
gene id: 288004:AL038_RS10655
uniprot id: A0A2N9YGW4
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

288004:AL038 RS15835
gene id: 288004:AL038_RS15835
uniprot id: A0A2N9YE17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

288004:AL038 RS01440
gene id: 288004:AL038_RS01440
uniprot id: A0A2N9YC74
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

288004:AL038 RS07515
gene id: 288004:AL038_RS07515
uniprot id: A0A2N9YI72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

288004:AL038 RS11860
gene id: 288004:AL038_RS11860
uniprot id: A0A2N9YFZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

288004:AL038 RS11560
gene id: 288004:AL038_RS11560
uniprot id: A0A2N9YG42
names: Similarity
messages: Belongs to the UDPGP type 2 family.

288004:AL038 RS02235
gene id: 288004:AL038_RS02235
uniprot id: A0A2N9YBR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

288004:AL038 RS05685
gene id: 288004:AL038_RS05685
uniprot id: A0A2N9YA12
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

288004:AL038 RS08440
gene id: 288004:AL038_RS08440
uniprot id: A0A2N9YII8
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS03310
gene id: 288004:AL038_RS03310
uniprot id: A0A2N9YJ00
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

288004:AL038 RS09750
gene id: 288004:AL038_RS09750
uniprot id: A0A2N9YGZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS13765
gene id: 288004:AL038_RS13765
uniprot id: A0A2N9YF46
names: Similarity
messages: Belongs to the GSP E family.

288004:AL038 RS11920
gene id: 288004:AL038_RS11920
uniprot id: A0A2N9YFY8
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

288004:AL038 RS10060
gene id: 288004:AL038_RS10060
uniprot id: A0A2N9YGZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

288004:AL038 RS01155
gene id: 288004:AL038_RS01155
uniprot id: A0A2N9YCC6
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

288004:AL038 RS00540
gene id: 288004:AL038_RS00540
uniprot id: A0A2N9YCL1
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS03540
gene id: 288004:AL038_RS03540
uniprot id: A0A2N9YB42
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

288004:AL038 RS12800
gene id: 288004:AL038_RS12800
uniprot id: A0A2N9YFV7
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

288004:AL038 RS00425
gene id: 288004:AL038_RS00425
uniprot id: A0A2N9YCM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

288004:AL038 RS12265
gene id: 288004:AL038_RS12265
uniprot id: A0A2N9YFR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

288004:AL038 RS07785
gene id: 288004:AL038_RS07785
uniprot id: A0A2N9YHX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

288004:AL038 RS13860
gene id: 288004:AL038_RS13860
uniprot id: A0A2N9YF27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

288004:AL038 RS10970
gene id: 288004:AL038_RS10970
uniprot id: A0A2N9YG79
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

288004:AL038 RS13075
gene id: 288004:AL038_RS13075
uniprot id: A0A2N9YFE3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

288004:AL038 RS08625
gene id: 288004:AL038_RS08625
uniprot id: A0A2N9YHY6
names: Similarity
messages: Belongs to the universal stress protein A family.

288004:AL038 RS14470
gene id: 288004:AL038_RS14470
uniprot id: A0A2N9YF32
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

288004:AL038 RS04665
gene id: 288004:AL038_RS04665
uniprot id: A0A2N9YAJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

288004:AL038 RS01800
gene id: 288004:AL038_RS01800
uniprot id: A0A2N9YBX0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

288004:AL038 RS15455
gene id: 288004:AL038_RS15455
uniprot id: A0A2N9YE92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

288004:AL038 RS14845
gene id: 288004:AL038_RS14845
uniprot id: A0A2N9YER8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

288004:AL038 RS03325
gene id: 288004:AL038_RS03325
uniprot id: A0A2N9YBC7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

288004:AL038 RS13350
gene id: 288004:AL038_RS13350
uniprot id: A0A2N9YFB9
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

288004:AL038 RS17660
gene id: 288004:AL038_RS17660
uniprot id: A0A2N9YD54
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

288004:AL038 RS02445
gene id: 288004:AL038_RS02445
uniprot id: A0A2N9YBV2
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

288004:AL038 RS14485
gene id: 288004:AL038_RS14485
uniprot id: A0A2N9YEW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

288004:AL038 RS00345
gene id: 288004:AL038_RS00345
uniprot id: A0A2N9YCS5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

288004:AL038 RS17695
gene id: 288004:AL038_RS17695
uniprot id: A0A2N9YD53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

288004:AL038 RS13525
gene id: 288004:AL038_RS13525
uniprot id: A0A2N9YFH8
names: Similarity
messages: Belongs to the bacterial secretin family.

288004:AL038 RS09745
gene id: 288004:AL038_RS09745
uniprot id: A0A2N9YHC1
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

288004:AL038 RS07840
gene id: 288004:AL038_RS07840
uniprot id: A0A2N9YJH7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

288004:AL038 RS12575
gene id: 288004:AL038_RS12575
uniprot id: A0A2N9YGF6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS07640
gene id: 288004:AL038_RS07640
uniprot id: A0A2N9YI20
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

288004:AL038 RS03340
gene id: 288004:AL038_RS03340
uniprot id: A0A2N9YB59
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

288004:AL038 RS01105
gene id: 288004:AL038_RS01105
uniprot id: A0A2N9YC96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

288004:AL038 RS13040
gene id: 288004:AL038_RS13040
uniprot id: A0A2N9YFR7
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

288004:AL038 RS02755
gene id: 288004:AL038_RS02755
uniprot id: A0A2N9YBH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

288004:AL038 RS03675
gene id: 288004:AL038_RS03675
uniprot id: A0A2N9YAZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

288004:AL038 RS07430
gene id: 288004:AL038_RS07430
uniprot id: A0A2N9YIN0
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

288004:AL038 RS07065
gene id: 288004:AL038_RS07065
uniprot id: A0A2N9YIC7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

288004:AL038 RS02130
gene id: 288004:AL038_RS02130
uniprot id: A0A2N9YBR6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

288004:AL038 RS13985
gene id: 288004:AL038_RS13985
uniprot id: A0A2N9YF43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

288004:AL038 RS14195
gene id: 288004:AL038_RS14195
uniprot id: A0A2N9YEV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

288004:AL038 RS08060
gene id: 288004:AL038_RS08060
uniprot id: A0A2N9YHS0
names: Similarity
messages: Belongs to the MlaA family.

288004:AL038 RS16805
gene id: 288004:AL038_RS16805
uniprot id: A0A2N9YDJ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

288004:AL038 RS14345
gene id: 288004:AL038_RS14345
uniprot id: A0A2N9YES6
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS12125
gene id: 288004:AL038_RS12125
uniprot id: A0A2N9YFW5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

288004:AL038 RS11130
gene id: 288004:AL038_RS11130
uniprot id: A0A2N9YGE7
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

288004:AL038 RS14950
gene id: 288004:AL038_RS14950
uniprot id: A0A2N9YEG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

288004:AL038 RS04775
gene id: 288004:AL038_RS04775
uniprot id: A0A2N9YAH3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

288004:AL038 RS08070
gene id: 288004:AL038_RS08070
uniprot id: A0A2N9YI65
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

288004:AL038 RS15940
gene id: 288004:AL038_RS15940
uniprot id: A0A2N9YDZ3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

288004:AL038 RS14415
gene id: 288004:AL038_RS14415
uniprot id: A0A2N9YER5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

288004:AL038 RS13175
gene id: 288004:AL038_RS13175
uniprot id: A0A2N9YFC4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

288004:AL038 RS07770
gene id: 288004:AL038_RS07770
uniprot id: A0A2N9YI52
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

288004:AL038 RS00780
gene id: 288004:AL038_RS00780
uniprot id: A0A2N9YCH5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

288004:AL038 RS09265
gene id: 288004:AL038_RS09265
uniprot id: A0A2N9YHL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

288004:AL038 RS12280
gene id: 288004:AL038_RS12280
uniprot id: A0A2N9YGK7
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

288004:AL038 RS05795
gene id: 288004:AL038_RS05795
uniprot id: A0A2N9Y9X7
names: Similarity
messages: Belongs to the oxoprolinase family.

288004:AL038 RS17205
gene id: 288004:AL038_RS17205
uniprot id: A0A2N9YDE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

288004:AL038 RS01940
gene id: 288004:AL038_RS01940
uniprot id: A0A2N9YBY4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

288004:AL038 RS06765
gene id: 288004:AL038_RS06765
uniprot id: A0A2N9YIE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

288004:AL038 RS09285
gene id: 288004:AL038_RS09285
uniprot id: A0A2N9YHM7
names: Similarity
messages: Belongs to the UPF0225 family.

288004:AL038 RS01760
gene id: 288004:AL038_RS01760
uniprot id: A0A2N9YBX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

288004:AL038 RS01700
gene id: 288004:AL038_RS01700
uniprot id: A0A2N9YBZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

288004:AL038 RS02315
gene id: 288004:AL038_RS02315
uniprot id: A0A2N9YBP1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

288004:AL038 RS01535
gene id: 288004:AL038_RS01535
uniprot id: A0A2N9YC69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

288004:AL038 RS04910
gene id: 288004:AL038_RS04910
uniprot id: A0A2N9YAD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

288004:AL038 RS17235
gene id: 288004:AL038_RS17235
uniprot id: A0A2N9YDA5
names: Similarity
messages: Belongs to the peptidase M17 family.

288004:AL038 RS16900
gene id: 288004:AL038_RS16900
uniprot id: A0A2N9YDK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

288004:AL038 RS12510
gene id: 288004:AL038_RS12510
uniprot id: A0A2N9YFQ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS08190
gene id: 288004:AL038_RS08190
uniprot id: A0A2N9YHR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

288004:AL038 RS12360
gene id: 288004:AL038_RS12360
uniprot id: A0A2N9YFR3
names: Similarity
messages: Belongs to the UPF0166 family.

288004:AL038 RS15925
gene id: 288004:AL038_RS15925
uniprot id: A0A2N9YE23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

288004:AL038 RS12760
gene id: 288004:AL038_RS12760
uniprot id: A0A2N9YFM0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

288004:AL038 RS12365
gene id: 288004:AL038_RS12365
uniprot id: A0A2N9YFT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

288004:AL038 RS02945
gene id: 288004:AL038_RS02945
uniprot id: A0A2N9YBD0
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

288004:AL038 RS10335
gene id: 288004:AL038_RS10335
uniprot id: A0A2N9YGP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

288004:AL038 RS10340
gene id: 288004:AL038_RS10340
uniprot id: A0A650GCW7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

288004:AL038 RS15805
gene id: 288004:AL038_RS15805
uniprot id: A0A2N9YE24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

288004:AL038 RS14455
gene id: 288004:AL038_RS14455
uniprot id: A0A2N9YJ85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

288004:AL038 RS17240
gene id: 288004:AL038_RS17240
uniprot id: A0A2N9YDB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS06415
gene id: 288004:AL038_RS06415
uniprot id: A0A2N9YIM4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

288004:AL038 RS17890
gene id: 288004:AL038_RS17890
uniprot id: A0A2N9YD39
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

288004:AL038 RS15120
gene id: 288004:AL038_RS15120
uniprot id: A0A2N9YEF7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

288004:AL038 RS06210
gene id: 288004:AL038_RS06210
uniprot id: A0A2N9YIU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

288004:AL038 RS13405
gene id: 288004:AL038_RS13405
uniprot id: A0A2N9YF89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

288004:AL038 RS15250
gene id: 288004:AL038_RS15250
uniprot id: A0A2N9YEC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

288004:AL038 RS10550
gene id: 288004:AL038_RS10550
uniprot id: A0A2N9YHG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

288004:AL038 RS05635
gene id: 288004:AL038_RS05635
uniprot id: A0A2N9YA27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

288004:AL038 RS00410
gene id: 288004:AL038_RS00410
uniprot id: A0A2N9YCP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

288004:AL038 RS14605
gene id: 288004:AL038_RS14605
uniprot id: A0A2N9YEM6
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

288004:AL038 RS04795
gene id: 288004:AL038_RS04795
uniprot id: A0A2N9YAF9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

288004:AL038 RS04765
gene id: 288004:AL038_RS04765
uniprot id: A0A2N9YAF1
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

288004:AL038 RS15100
gene id: 288004:AL038_RS15100
uniprot id: A0A2N9YEE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

288004:AL038 RS06525
gene id: 288004:AL038_RS06525
uniprot id: A0A2N9YIR2
names: Similarity
messages: Belongs to the NifZ family.

288004:AL038 RS13630
gene id: 288004:AL038_RS13630
uniprot id: A0A2N9YF68
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

288004:AL038 RS12190
gene id: 288004:AL038_RS12190
uniprot id: A0A2N9YFV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

288004:AL038 RS15545
gene id: 288004:AL038_RS15545
uniprot id: A0A2N9YE74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

288004:AL038 RS03265
gene id: 288004:AL038_RS03265
uniprot id: A0A2N9YJ90
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

288004:AL038 RS04800
gene id: 288004:AL038_RS04800
uniprot id: A0A2N9YAF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

288004:AL038 RS08920
gene id: 288004:AL038_RS08920
uniprot id: A0A2N9YHU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

288004:AL038 RS11580
gene id: 288004:AL038_RS11580
uniprot id: A0A2N9YG44
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

288004:AL038 RS10865
gene id: 288004:AL038_RS10865
uniprot id: A0A2N9YGS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS10110
gene id: 288004:AL038_RS10110
uniprot id: A0A2N9YGY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

288004:AL038 RS11925
gene id: 288004:AL038_RS11925
uniprot id: A0A2N9YG93
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

288004:AL038 RS01570
gene id: 288004:AL038_RS01570
uniprot id: A0A2N9YC57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

288004:AL038 RS07910
gene id: 288004:AL038_RS07910
uniprot id: A0A2N9YIT4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

288004:AL038 RS03570
gene id: 288004:AL038_RS03570
uniprot id: A0A2N9YB14
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

288004:AL038 RS16525
gene id: 288004:AL038_RS16525
uniprot id: A0A2N9YJL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

288004:AL038 RS00635
gene id: 288004:AL038_RS00635
uniprot id: A0A2N9YCK5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

288004:AL038 RS01825
gene id: 288004:AL038_RS01825
uniprot id: A0A2N9YC16
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS08735
gene id: 288004:AL038_RS08735
uniprot id: A0A2N9YHL3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

288004:AL038 RS03890
gene id: 288004:AL038_RS03890
uniprot id: A0A2N9YAX0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

288004:AL038 RS10345
gene id: 288004:AL038_RS10345
uniprot id: A0A2N9YGJ4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

288004:AL038 RS17280
gene id: 288004:AL038_RS17280
uniprot id: A0A2N9YJ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

288004:AL038 RS08385
gene id: 288004:AL038_RS08385
uniprot id: A0A2N9YIK0
names: Similarity
messages: Belongs to the thioredoxin family.

288004:AL038 RS04025
gene id: 288004:AL038_RS04025
uniprot id: A0A2N9YAT8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

288004:AL038 RS09980
gene id: 288004:AL038_RS09980
uniprot id: A0A2N9YH83
names: Similarity
messages: Belongs to the phosphohexose mutase family.

288004:AL038 RS03475
gene id: 288004:AL038_RS03475
uniprot id: A0A2N9YB65
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

288004:AL038 RS07810
gene id: 288004:AL038_RS07810
uniprot id: A0A2N9YIW3
names: Similarity
messages: Belongs to the HPrK/P family.

288004:AL038 RS07470
gene id: 288004:AL038_RS07470
uniprot id: A0A2N9YI64
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

288004:AL038 RS14065
gene id: 288004:AL038_RS14065
uniprot id: A0A2N9YEX4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

288004:AL038 RS10285
gene id: 288004:AL038_RS10285
uniprot id: A0A2N9YGK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

288004:AL038 RS01730
gene id: 288004:AL038_RS01730
uniprot id: A0A2N9YC05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

288004:AL038 RS14350
gene id: 288004:AL038_RS14350
uniprot id: A0A2N9YET8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

288004:AL038 RS11165
gene id: 288004:AL038_RS11165
uniprot id: A0A2N9YGC7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS11895
gene id: 288004:AL038_RS11895
uniprot id: A0A2N9YFY6
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS16555
gene id: 288004:AL038_RS16555
uniprot id: A0A2N9YDN7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

288004:AL038 RS06390
gene id: 288004:AL038_RS06390
uniprot id: A0A2N9YJI5
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

288004:AL038 RS07080
gene id: 288004:AL038_RS07080
uniprot id: A0A2N9YIU7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

288004:AL038 RS16255
gene id: 288004:AL038_RS16255
uniprot id: A0A2N9YDU8
names: Subcellular Location Annotation
messages: Cytoplasm

288004:AL038 RS16530
gene id: 288004:AL038_RS16530
uniprot id: A0A2N9YDQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

288004:AL038 RS01460
gene id: 288004:AL038_RS01460
uniprot id: A0A2N9YC32
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

288004:AL038 RS09245
gene id: 288004:AL038_RS09245
uniprot id: A0A2N9YHF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

288004:AL038 RS16750
gene id: 288004:AL038_RS16750
uniprot id: A0A2N9YDM6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

288004:AL038 RS02465
gene id: 288004:AL038_RS02465
uniprot id: A0A2N9YBK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

288004:AL038 RS16345
gene id: 288004:AL038_RS16345
uniprot id: A0A2N9YDV8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

288004:AL038 RS10920
gene id: 288004:AL038_RS10920
uniprot id: A0A2N9YGD6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

288004:AL038 RS03125
gene id: 288004:AL038_RS03125
uniprot id: A0A2N9YB95
names: Similarity
messages: Belongs to the bacterial glucokinase family.

288004:AL038 RS08545
gene id: 288004:AL038_RS08545
uniprot id: A0A2N9YHK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

288004:AL038 RS13790
gene id: 288004:AL038_RS13790
uniprot id: A0A2N9YFE4
names: Similarity
messages: Belongs to the citrate synthase family.

288004:AL038 RS03625
gene id: 288004:AL038_RS03625
uniprot id: A0A2N9YB10
names: Function
names: Subunit
messages: Interacts with sigma-54.
messages: Required for activation of most nif operons, which are directly involved in nitrogen fixation.

288004:AL038 RS03745
gene id: 288004:AL038_RS03745
uniprot id: A0A2N9YAZ2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-101 inactivates the nitrogenase reductase and regulates nitrogenase activity.

288004:AL038 RS16725
gene id: 288004:AL038_RS16725
uniprot id: A0A2N9YDZ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

288004:AL038 RS06585
gene id: 288004:AL038_RS06585
uniprot id: A0A2N9YII3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

288004:AL038 RS03690
gene id: 288004:AL038_RS03690
uniprot id: A0A2N9YB30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS07680
gene id: 288004:AL038_RS07680
uniprot id: A0A2N9YI51
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS11880
gene id: 288004:AL038_RS11880
uniprot id: A0A2N9YG03
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

288004:AL038 RS10230
gene id: 288004:AL038_RS10230
uniprot id: A0A2N9YGL5
names: Similarity
messages: Belongs to the CapA family.

288004:AL038 RS15050
gene id: 288004:AL038_RS15050
uniprot id: A0A2N9YEF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

288004:AL038 RS05495
gene id: 288004:AL038_RS05495
uniprot id: A0A2N9YA38
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

288004:AL038 RS13870
gene id: 288004:AL038_RS13870
uniprot id: A0A2N9YF13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

288004:AL038 RS14020
gene id: 288004:AL038_RS14020
uniprot id: A0A2N9YEZ4
names: Similarity
messages: Belongs to the peptidase M16 family.

288004:AL038 RS01985
gene id: 288004:AL038_RS01985
uniprot id: A0A2N9YBV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

288004:AL038 RS00115
gene id: 288004:AL038_RS00115
uniprot id: A0A2N9YCV5
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

288004:AL038 RS10650
gene id: 288004:AL038_RS10650
uniprot id: A0A650GDU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

288004:AL038 RS17955
gene id: 288004:AL038_RS17955
uniprot id: A0A2N9YD38
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons.

288004:AL038 RS00860
gene id: 288004:AL038_RS00860
uniprot id: A0A2N9YCF5
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS12260
gene id: 288004:AL038_RS12260
uniprot id: A0A2N9YG40
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

288004:AL038 RS03100
gene id: 288004:AL038_RS03100
uniprot id: A0A2N9YBD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS00415
gene id: 288004:AL038_RS00415
uniprot id: A0A2N9YCN6
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

288004:AL038 RS05490
gene id: 288004:AL038_RS05490
uniprot id: A0A2N9YA35
names: Subcellular Location Annotation
messages: extracellular matrix

288004:AL038 RS00845
gene id: 288004:AL038_RS00845
uniprot id: A0A2N9YCG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

288004:AL038 RS08415
gene id: 288004:AL038_RS08415
uniprot id: A0A2N9YHQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

288004:AL038 RS14575
gene id: 288004:AL038_RS14575
uniprot id: A0A2N9YEP9
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

288004:AL038 RS06185
gene id: 288004:AL038_RS06185
uniprot id: A0A2N9YIS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

288004:AL038 RS13815
gene id: 288004:AL038_RS13815
uniprot id: A0A2N9YJQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

288004:AL038 RS16610
gene id: 288004:AL038_RS16610
uniprot id: A0A2N9YE14
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

288004:AL038 RS05465
gene id: 288004:AL038_RS05465
uniprot id: A0A2N9YA48
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

288004:AL038 RS05090
gene id: 288004:AL038_RS05090
uniprot id: A0A2N9YIZ3
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

288004:AL038 RS06420
gene id: 288004:AL038_RS06420
uniprot id: A0A2N9YIR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

288004:AL038 RS13920
gene id: 288004:AL038_RS13920
uniprot id: A0A2N9YF05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

288004:AL038 RS03380
gene id: 288004:AL038_RS03380
uniprot id: A0A2N9YB40
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

288004:AL038 RS03635
gene id: 288004:AL038_RS03635
uniprot id: A0A2N9YB09
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

288004:AL038 RS11685
gene id: 288004:AL038_RS11685
uniprot id: A0A2N9YG24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

288004:AL038 RS03535
gene id: 288004:AL038_RS03535
uniprot id: A0A2N9YB54
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

288004:AL038 RS11065
gene id: 288004:AL038_RS11065
uniprot id: A0A2N9YGG1
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

288004:AL038 RS05285
gene id: 288004:AL038_RS05285
uniprot id: A0A2N9YA65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

288004:AL038 RS10025
gene id: 288004:AL038_RS10025
uniprot id: A0A2N9YGW6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS04805
gene id: 288004:AL038_RS04805
uniprot id: A0A2N9YAF5
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

288004:AL038 RS10745
gene id: 288004:AL038_RS10745
uniprot id: A0A2N9YGH4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

288004:AL038 RS09620
gene id: 288004:AL038_RS09620
uniprot id: A0A2N9YHE1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

288004:AL038 RS07595
gene id: 288004:AL038_RS07595
uniprot id: A0A2N9YI50
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

288004:AL038 RS09015
gene id: 288004:AL038_RS09015
uniprot id: A0A2N9YHG3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

288004:AL038 RS06000
gene id: 288004:AL038_RS06000
uniprot id: A0A2N9YJM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

288004:AL038 RS16380
gene id: 288004:AL038_RS16380
uniprot id: A0A2N9YE52
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

288004:AL038 RS02655
gene id: 288004:AL038_RS02655
uniprot id: A0A2N9YBQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

288004:AL038 RS07905
gene id: 288004:AL038_RS07905
uniprot id: A0A2N9YHY7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

288004:AL038 RS06655
gene id: 288004:AL038_RS06655
uniprot id: A0A2N9YIU6
names: Similarity
messages: Belongs to the GppA/Ppx family.

288004:AL038 RS15735
gene id: 288004:AL038_RS15735
uniprot id: A0A2N9YE46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

288004:AL038 RS09870
gene id: 288004:AL038_RS09870
uniprot id: A0A2N9YH01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

288004:AL038 RS07500
gene id: 288004:AL038_RS07500
uniprot id: A0A2N9YIA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

288004:AL038 RS12945
gene id: 288004:AL038_RS12945
uniprot id: A0A2N9YFJ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

288004:AL038 RS02855
gene id: 288004:AL038_RS02855
uniprot id: A0A2N9YBE6
names: Similarity
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.

288004:AL038 RS00390
gene id: 288004:AL038_RS00390
uniprot id: A0A2N9YCP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

288004:AL038 RS03645
gene id: 288004:AL038_RS03645
uniprot id: A0A2N9YB08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

288004:AL038 RS08485
gene id: 288004:AL038_RS08485
uniprot id: A0A2N9YHP9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

288004:AL038 RS15280
gene id: 288004:AL038_RS15280
uniprot id: A0A2N9YEC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

288004:AL038 RS06405
gene id: 288004:AL038_RS06405
uniprot id: A0A2N9YIT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

288004:AL038 RS11870
gene id: 288004:AL038_RS11870
uniprot id: A0A2N9YFX7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

288004:AL038 RS16370
gene id: 288004:AL038_RS16370
uniprot id: A0A2N9YDR7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

288004:AL038 RS08135
gene id: 288004:AL038_RS08135
uniprot id: A0A2N9YHS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

288004:AL038 RS09840
gene id: 288004:AL038_RS09840
uniprot id: A0A2N9YH38
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS15395
gene id: 288004:AL038_RS15395
uniprot id: A0A2N9YE90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

288004:AL038 RS10330
gene id: 288004:AL038_RS10330
uniprot id: A0A2N9YGU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.

288004:AL038 RS16650
gene id: 288004:AL038_RS16650
uniprot id: A0A2N9YDN6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

288004:AL038 RS00430
gene id: 288004:AL038_RS00430
uniprot id: A0A2N9YCN8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

288004:AL038 RS07825
gene id: 288004:AL038_RS07825
uniprot id: A0A2N9YHY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

288004:AL038 RS13255
gene id: 288004:AL038_RS13255
uniprot id: A0A2N9YFD0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

288004:AL038 RS00640
gene id: 288004:AL038_RS00640
uniprot id: A0A2N9YCJ3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS10840
gene id: 288004:AL038_RS10840
uniprot id: A0A2N9YGI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

288004:AL038 RS10170
gene id: 288004:AL038_RS10170
uniprot id: A0A2N9YGX5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

288004:AL038 RS16540
gene id: 288004:AL038_RS16540
uniprot id: A0A2N9YDN8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

288004:AL038 RS09170
gene id: 288004:AL038_RS09170
uniprot id: A0A2N9YHD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

288004:AL038 RS02205
gene id: 288004:AL038_RS02205
uniprot id: A0A2N9YBQ0
names: Function
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

288004:AL038 RS01240
gene id: 288004:AL038_RS01240
uniprot id: A0A2N9YC90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

288004:AL038 RS06545
gene id: 288004:AL038_RS06545
uniprot id: A0A2N9YIW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

288004:AL038 RS04960
gene id: 288004:AL038_RS04960
uniprot id: A0A2N9YAC7
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS13310
gene id: 288004:AL038_RS13310
uniprot id: A0A2N9YFC3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

288004:AL038 RS01925
gene id: 288004:AL038_RS01925
uniprot id: A0A2N9YC27
names: Similarity
messages: Belongs to the NodU/CmcH family.

288004:AL038 RS08720
gene id: 288004:AL038_RS08720
uniprot id: A0A2N9YHK5
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

288004:AL038 RS15285
gene id: 288004:AL038_RS15285
uniprot id: A0A2N9YEB6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS16855
gene id: 288004:AL038_RS16855
uniprot id: A0A2N9YDK3
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

288004:AL038 RS17700
gene id: 288004:AL038_RS17700
uniprot id: A0A2N9YDF6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

288004:AL038 RS13995
gene id: 288004:AL038_RS13995
uniprot id: A0A2N9YF10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

288004:AL038 RS04370
gene id: 288004:AL038_RS04370
uniprot id: A0A2N9YAP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

288004:AL038 RS11325
gene id: 288004:AL038_RS11325
uniprot id: A0A2N9YG66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

288004:AL038 RS11990
gene id: 288004:AL038_RS11990
uniprot id: A0A2N9YFW0
names: Similarity
messages: Belongs to the group II decarboxylase family.

288004:AL038 RS06730
gene id: 288004:AL038_RS06730
uniprot id: A0A2N9YJD4
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

288004:AL038 RS06450
gene id: 288004:AL038_RS06450
uniprot id: A0A2N9YJ49
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

288004:AL038 RS00465
gene id: 288004:AL038_RS00465
uniprot id: A0A2N9YCM1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Membrane

288004:AL038 RS12195
gene id: 288004:AL038_RS12195
uniprot id: A0A2N9YFT8
names: Caution
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS08030
gene id: 288004:AL038_RS08030
uniprot id: A0A2N9YIR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

288004:AL038 RS09665
gene id: 288004:AL038_RS09665
uniprot id: A0A2N9YH26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

288004:AL038 RS12600
gene id: 288004:AL038_RS12600
uniprot id: A0A2N9YJR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

288004:AL038 RS13465
gene id: 288004:AL038_RS13465
uniprot id: A0A2N9YFE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

288004:AL038 RS04560
gene id: 288004:AL038_RS04560
uniprot id: A0A2N9YAK5
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

288004:AL038 RS07580
gene id: 288004:AL038_RS07580
uniprot id: A0A2N9YI66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

288004:AL038 RS11805
gene id: 288004:AL038_RS11805
uniprot id: A0A2N9YG04
names: Subcellular Location Annotation
messages: Cytoplasm

288004:AL038 RS02745
gene id: 288004:AL038_RS02745
uniprot id: A0A2N9YJH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

288004:AL038 RS04990
gene id: 288004:AL038_RS04990
uniprot id: A0A2N9YAC1
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS08270
gene id: 288004:AL038_RS08270
uniprot id: A0A2N9YI49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

288004:AL038 RS01720
gene id: 288004:AL038_RS01720
uniprot id: A0A2N9YC39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

288004:AL038 RS13505
gene id: 288004:AL038_RS13505
uniprot id: A0A2N9YFK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

288004:AL038 RS01410
gene id: 288004:AL038_RS01410
uniprot id: A0A2N9YCA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS00900
gene id: 288004:AL038_RS00900
uniprot id: A0A2N9YCG7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

288004:AL038 RS08480
gene id: 288004:AL038_RS08480
uniprot id: A0A2N9YHL8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

288004:AL038 RS09145
gene id: 288004:AL038_RS09145
uniprot id: A0A2N9YHA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

288004:AL038 RS12680
gene id: 288004:AL038_RS12680
uniprot id: A0A2N9YFN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

288004:AL038 RS00805
gene id: 288004:AL038_RS00805
uniprot id: A0A2N9YCG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

288004:AL038 RS05015
gene id: 288004:AL038_RS05015
uniprot id: A0A2N9YAC2
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

288004:AL038 RS16250
gene id: 288004:AL038_RS16250
uniprot id: A0A0N9M4S5
names: Subcellular Location Annotation
messages: Cytoplasm

288004:AL038 RS02700
gene id: 288004:AL038_RS02700
uniprot id: A0A2N9YBH9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

288004:AL038 RS08290
gene id: 288004:AL038_RS08290
uniprot id: A0A2N9YHN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

288004:AL038 RS01805
gene id: 288004:AL038_RS01805
uniprot id: A0A2N9YC10
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

288004:AL038 RS08610
gene id: 288004:AL038_RS08610
uniprot id: A0A2N9YHJ7
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS13685
gene id: 288004:AL038_RS13685
uniprot id: A0A2N9YF42
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

288004:AL038 RS05535
gene id: 288004:AL038_RS05535
uniprot id: A0A2N9YA43
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

288004:AL038 RS16275
gene id: 288004:AL038_RS16275
uniprot id: A0A2N9YDW9
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

288004:AL038 RS10135
gene id: 288004:AL038_RS10135
uniprot id: A0A2N9YH48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

288004:AL038 RS08295
gene id: 288004:AL038_RS08295
uniprot id: A0A2N9YHS8
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

288004:AL038 RS16870
gene id: 288004:AL038_RS16870
uniprot id: A0A2N9YDH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

288004:AL038 RS07375
gene id: 288004:AL038_RS07375
uniprot id: A0A2N9YIP0
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

288004:AL038 RS09675
gene id: 288004:AL038_RS09675
uniprot id: A0A2N9YH10
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

288004:AL038 RS00180
gene id: 288004:AL038_RS00180
uniprot id: A0A2N9YCT6
names: Similarity
messages: Belongs to the plasmid replication initiation factor family.

288004:AL038 RS10605
gene id: 288004:AL038_RS10605
uniprot id: A0A2N9YJE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

288004:AL038 RS16945
gene id: 288004:AL038_RS16945
uniprot id: A0A2N9YDG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

288004:AL038 RS13265
gene id: 288004:AL038_RS13265
uniprot id: A0A2N9YFC5
names: Similarity
messages: Belongs to the asparagine synthetase family.

288004:AL038 RS16280
gene id: 288004:AL038_RS16280
uniprot id: A0A2N9YE37
names: Similarity
messages: Belongs to the AlaDH/PNT family.

288004:AL038 RS10810
gene id: 288004:AL038_RS10810
uniprot id: A0A2N9YJI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

288004:AL038 RS02135
gene id: 288004:AL038_RS02135
uniprot id: A0A2N9YBX1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

288004:AL038 RS03035
gene id: 288004:AL038_RS03035
uniprot id: A0A2N9YBC3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS13050
gene id: 288004:AL038_RS13050
uniprot id: A0A2N9YFI3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

288004:AL038 RS00650
gene id: 288004:AL038_RS00650
uniprot id: A0A2N9YCJ4
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

288004:AL038 RS06510
gene id: 288004:AL038_RS06510
uniprot id: A0A2N9YJI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.
messages: Homodimer.

288004:AL038 RS13905
gene id: 288004:AL038_RS13905
uniprot id: A0A2N9YF01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

288004:AL038 RS13755
gene id: 288004:AL038_RS13755
uniprot id: A0A2N9YF79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

288004:AL038 RS00775
gene id: 288004:AL038_RS00775
uniprot id: A0A2N9YCK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

288004:AL038 RS10400
gene id: 288004:AL038_RS10400
uniprot id: A0A2N9YGI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

288004:AL038 RS01745
gene id: 288004:AL038_RS01745
uniprot id: A0A2N9YC02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

288004:AL038 RS07885
gene id: 288004:AL038_RS07885
uniprot id: A0A2N9YHU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

288004:AL038 RS14500
gene id: 288004:AL038_RS14500
uniprot id: A0A2N9YEQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

288004:AL038 RS13395
gene id: 288004:AL038_RS13395
uniprot id: A0A2N9YFB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

288004:AL038 RS07215
gene id: 288004:AL038_RS07215
uniprot id: A0A2N9YI77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS12835
gene id: 288004:AL038_RS12835
uniprot id: A0A2N9YFJ2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

288004:AL038 RS00590
gene id: 288004:AL038_RS00590
uniprot id: A0A2N9YCK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS07135
gene id: 288004:AL038_RS07135
uniprot id: A0A2N9YIT8
names: Similarity
messages: Belongs to the disproportionating enzyme family.

288004:AL038 RS08555
gene id: 288004:AL038_RS08555
uniprot id: A0A2N9YHP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS04495
gene id: 288004:AL038_RS04495
uniprot id: A0A2N9YJP5
names: Function
names: Similarity
names: Subunit
messages: Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

288004:AL038 RS15500
gene id: 288004:AL038_RS15500
uniprot id: A0A2N9YE67
names: Function
names: Similarity
messages: Belongs to the CowN family.
messages: Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO.

288004:AL038 RS02630
gene id: 288004:AL038_RS02630
uniprot id: A0A2N9YBI0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS07710
gene id: 288004:AL038_RS07710
uniprot id: A0A650GDS6
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS18090
gene id: 288004:AL038_RS18090
uniprot id: A0A2N9YD18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

288004:AL038 RS08580
gene id: 288004:AL038_RS08580
uniprot id: A0A2N9YHS2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

288004:AL038 RS08860
gene id: 288004:AL038_RS08860
uniprot id: A0A2N9YHV2
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

288004:AL038 RS15650
gene id: 288004:AL038_RS15650
uniprot id: A0A2N9YE48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

288004:AL038 RS07445
gene id: 288004:AL038_RS07445
uniprot id: A0A2N9YI58
names: Similarity
messages: Belongs to the HSP15 family.

288004:AL038 RS11335
gene id: 288004:AL038_RS11335
uniprot id: A0A2N9YH23
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

288004:AL038 RS07425
gene id: 288004:AL038_RS07425
uniprot id: A0A2N9YJ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

288004:AL038 RS10590
gene id: 288004:AL038_RS10590
uniprot id: A0A2N9YGX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

288004:AL038 RS14875
gene id: 288004:AL038_RS14875
uniprot id: A0A2N9YEX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

288004:AL038 RS07630
gene id: 288004:AL038_RS07630
uniprot id: A0A2N9YI57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

288004:AL038 RS12055
gene id: 288004:AL038_RS12055
uniprot id: A0A2N9YG70
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

288004:AL038 RS11445
gene id: 288004:AL038_RS11445
uniprot id: A0A2N9YG68
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

288004:AL038 RS12710
gene id: 288004:AL038_RS12710
uniprot id: A0A2N9YFM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

288004:AL038 RS13760
gene id: 288004:AL038_RS13760
uniprot id: A0A2N9YFC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

288004:AL038 RS06070
gene id: 288004:AL038_RS06070
uniprot id: A0A2N9YIY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

288004:AL038 RS12825
gene id: 288004:AL038_RS12825
uniprot id: A0A2N9YFU8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

288004:AL038 RS00840
gene id: 288004:AL038_RS00840
uniprot id: A0A2N9YCK7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

288004:AL038 RS04565
gene id: 288004:AL038_RS04565
uniprot id: A0A2N9YAL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

288004:AL038 RS17650
gene id: 288004:AL038_RS17650
uniprot id: A0A2N9YDG5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

288004:AL038 RS17065
gene id: 288004:AL038_RS17065
uniprot id: A0A2N9YDR1
names: Similarity
messages: Belongs to the UPF0235 family.

288004:AL038 RS00580
gene id: 288004:AL038_RS00580
uniprot id: A0A2N9YCJ8
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

288004:AL038 RS10700
gene id: 288004:AL038_RS10700
uniprot id: A0A2N9YGD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

288004:AL038 RS14480
gene id: 288004:AL038_RS14480
uniprot id: A0A2N9YEQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

288004:AL038 RS10305
gene id: 288004:AL038_RS10305
uniprot id: A0A2N9YGP7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

288004:AL038 RS00350
gene id: 288004:AL038_RS00350
uniprot id: A0A2N9YCR1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

288004:AL038 RS04180
gene id: 288004:AL038_RS04180
uniprot id: A0A2N9YAR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

288004:AL038 RS06045
gene id: 288004:AL038_RS06045
uniprot id: A0A2N9YJ42
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

288004:AL038 RS01030
gene id: 288004:AL038_RS01030
uniprot id: A0A2N9YCB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

288004:AL038 RS08155
gene id: 288004:AL038_RS08155
uniprot id: A0A2N9YHX2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

288004:AL038 RS10125
gene id: 288004:AL038_RS10125
uniprot id: A0A2N9YGN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

288004:AL038 RS09110
gene id: 288004:AL038_RS09110
uniprot id: A0A2N9YHB3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

288004:AL038 RS13895
gene id: 288004:AL038_RS13895
uniprot id: A0A2N9YF20
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

288004:AL038 RS14715
gene id: 288004:AL038_RS14715
uniprot id: A0A2N9YES5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

288004:AL038 RS05295
gene id: 288004:AL038_RS05295
uniprot id: A0A2N9YA60
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

288004:AL038 RS09655
gene id: 288004:AL038_RS09655
uniprot id: A0A2N9YH06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

288004:AL038 RS14490
gene id: 288004:AL038_RS14490
uniprot id: A0A2N9YER9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

288004:AL038 RS13020
gene id: 288004:AL038_RS13020
uniprot id: A0A2N9YFF5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

288004:AL038 RS09125
gene id: 288004:AL038_RS09125
uniprot id: A0A2N9YHQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

288004:AL038 RS08325
gene id: 288004:AL038_RS08325
uniprot id: A0A2N9YIK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

288004:AL038 RS02935
gene id: 288004:AL038_RS02935
uniprot id: A0A2N9YBH7
names: Similarity
messages: Belongs to the glutamate synthase family.

288004:AL038 RS10870
gene id: 288004:AL038_RS10870
uniprot id: A0A2N9YGF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

288004:AL038 RS03180
gene id: 288004:AL038_RS03180
uniprot id: A0A2N9YBB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

288004:AL038 RS13295
gene id: 288004:AL038_RS13295
uniprot id: A0A650GDW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

288004:AL038 RS06940
gene id: 288004:AL038_RS06940
uniprot id: A0A2N9YIQ9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

288004:AL038 RS05030
gene id: 288004:AL038_RS05030
uniprot id: A0A2N9YAA9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS07370
gene id: 288004:AL038_RS07370
uniprot id: A0A2N9YJ33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

288004:AL038 RS10880
gene id: 288004:AL038_RS10880
uniprot id: A0A2N9YH98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

288004:AL038 RS06155
gene id: 288004:AL038_RS06155
uniprot id: A0A2N9YIS9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

288004:AL038 RS01400
gene id: 288004:AL038_RS01400
uniprot id: A0A2N9YC89
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS17100
gene id: 288004:AL038_RS17100
uniprot id: A0A2N9YDQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

288004:AL038 RS13185
gene id: 288004:AL038_RS13185
uniprot id: A0A2N9YFF0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

288004:AL038 RS11310
gene id: 288004:AL038_RS11310
uniprot id: A0A2N9YG91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

288004:AL038 RS18005
gene id: 288004:AL038_RS18005
uniprot id: A0A2N9YD11
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

288004:AL038 RS10835
gene id: 288004:AL038_RS10835
uniprot id: A0A2N9YGU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

288004:AL038 RS13780
gene id: 288004:AL038_RS13780
uniprot id: A0A2N9YF17
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

288004:AL038 RS13785
gene id: 288004:AL038_RS13785
uniprot id: A0A2N9YF41
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

288004:AL038 RS03335
gene id: 288004:AL038_RS03335
uniprot id: A0A2N9YB50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

288004:AL038 RS03660
gene id: 288004:AL038_RS03660
uniprot id: A0A2N9YB21
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

288004:AL038 RS09720
gene id: 288004:AL038_RS09720
uniprot id: A0A2N9YH59
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

288004:AL038 RS13915
gene id: 288004:AL038_RS13915
uniprot id: A0A2N9YFC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

288004:AL038 RS09200
gene id: 288004:AL038_RS09200
uniprot id: A0A2N9YH64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

288004:AL038 RS04550
gene id: 288004:AL038_RS04550
uniprot id: A0A2N9YAI4
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS15145
gene id: 288004:AL038_RS15145
uniprot id: A0A2N9YEM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

288004:AL038 RS04485
gene id: 288004:AL038_RS04485
uniprot id: A0A2N9YAN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

288004:AL038 RS01480
gene id: 288004:AL038_RS01480
uniprot id: A0A2N9YC58
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

288004:AL038 RS10130
gene id: 288004:AL038_RS10130
uniprot id: A0A2N9YGU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS11655
gene id: 288004:AL038_RS11655
uniprot id: A0A2N9YGW9
names: Similarity
messages: Belongs to the Gram-positive plasmids replication protein type 1 family.

288004:AL038 RS15750
gene id: 288004:AL038_RS15750
uniprot id: A0A2N9YEH3
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

288004:AL038 RS06030
gene id: 288004:AL038_RS06030
uniprot id: A0A2N9YIV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

288004:AL038 RS16665
gene id: 288004:AL038_RS16665
uniprot id: A0A2N9YDL5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

288004:AL038 RS10270
gene id: 288004:AL038_RS10270
uniprot id: A0A2N9YGV7
names: Similarity
messages: Belongs to the HypD family.

288004:AL038 RS06910
gene id: 288004:AL038_RS06910
uniprot id: A0A2N9YIH8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

288004:AL038 RS11915
gene id: 288004:AL038_RS11915
uniprot id: A0A2N9YFS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

288004:AL038 RS17880
gene id: 288004:AL038_RS17880
uniprot id: A0A2N9YD28
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

288004:AL038 RS15670
gene id: 288004:AL038_RS15670
uniprot id: A0A2N9YE45
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

288004:AL038 RS17030
gene id: 288004:AL038_RS17030
uniprot id: A0A2N9YDD8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

288004:AL038 RS06425
gene id: 288004:AL038_RS06425
uniprot id: A0A2N9YIY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

288004:AL038 RS02020
gene id: 288004:AL038_RS02020
uniprot id: A0A2N9YBX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

288004:AL038 RS03430
gene id: 288004:AL038_RS03430
uniprot id: A0A2N9YB57
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

288004:AL038 RS16645
gene id: 288004:AL038_RS16645
uniprot id: A0A2N9YDY4
names: Similarity
messages: Belongs to the UPF0234 family.

288004:AL038 RS10640
gene id: 288004:AL038_RS10640
uniprot id: A0A2N9YJE2
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

288004:AL038 RS15270
gene id: 288004:AL038_RS15270
uniprot id: A0A2N9YJ94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

288004:AL038 RS09290
gene id: 288004:AL038_RS09290
uniprot id: A0A2N9YHC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

288004:AL038 RS06485
gene id: 288004:AL038_RS06485
uniprot id: A0A2N9YIM5
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

288004:AL038 RS15215
gene id: 288004:AL038_RS15215
uniprot id: A0A2N9YEC2
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

288004:AL038 RS05920
gene id: 288004:AL038_RS05920
uniprot id: A0A2N9Y9V4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

288004:AL038 RS17480
gene id: 288004:AL038_RS17480
uniprot id: A0A2N9YD95
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS15055
gene id: 288004:AL038_RS15055
uniprot id: A0A2N9YEG7
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

288004:AL038 RS08490
gene id: 288004:AL038_RS08490
uniprot id: A0A2N9YIH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

288004:AL038 RS17140
gene id: 288004:AL038_RS17140
uniprot id: A0A2N9YJ69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

288004:AL038 RS02150
gene id: 288004:AL038_RS02150
uniprot id: A0A2N9YBU8
names: Similarity
messages: Belongs to the transketolase family.

288004:AL038 RS07415
gene id: 288004:AL038_RS07415
uniprot id: A0A2N9YI62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

288004:AL038 RS08115
gene id: 288004:AL038_RS08115
uniprot id: A0A2N9YHR2
names: Similarity
messages: Belongs to the bacterial glucokinase family.

288004:AL038 RS01475
gene id: 288004:AL038_RS01475
uniprot id: A0A2N9YC82
names: Similarity
messages: Belongs to the pyruvate kinase family.

288004:AL038 RS07095
gene id: 288004:AL038_RS07095
uniprot id: A0A2N9YIG7
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

288004:AL038 RS12420
gene id: 288004:AL038_RS12420
uniprot id: A0A2N9YG13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifW family.
messages: Homotrimer; associates with NifD.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.

288004:AL038 RS03555
gene id: 288004:AL038_RS03555
uniprot id: A0A2N9YB15
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

288004:AL038 RS10070
gene id: 288004:AL038_RS10070
uniprot id: A0A2N9YJF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

288004:AL038 RS06965
gene id: 288004:AL038_RS06965
uniprot id: A0A2N9YJ96
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

288004:AL038 RS02010
gene id: 288004:AL038_RS02010
uniprot id: A0A2N9YBU4
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

288004:AL038 RS11940
gene id: 288004:AL038_RS11940
uniprot id: A0A2N9YFZ4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

288004:AL038 RS15030
gene id: 288004:AL038_RS15030
uniprot id: A0A2N9YEG0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

288004:AL038 RS14120
gene id: 288004:AL038_RS14120
uniprot id: A0A2N9YEW5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS05065
gene id: 288004:AL038_RS05065
uniprot id: A0A2N9YAB2
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

288004:AL038 RS00725
gene id: 288004:AL038_RS00725
uniprot id: A0A2N9YCI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

288004:AL038 RS17845
gene id: 288004:AL038_RS17845
uniprot id: A0A2N9YD12
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

288004:AL038 RS07535
gene id: 288004:AL038_RS07535
uniprot id: A0A2N9YJ15
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

288004:AL038 RS16600
gene id: 288004:AL038_RS16600
uniprot id: A0A2N9YDM9
names: Similarity
messages: Belongs to the MoaD family.

288004:AL038 RS00175
gene id: 288004:AL038_RS00175
uniprot id: A0A2N9YCW5
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS13680
gene id: 288004:AL038_RS13680
uniprot id: A0A2N9YFG4
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

288004:AL038 RS08280
gene id: 288004:AL038_RS08280
uniprot id: A0A2N9YHX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

288004:AL038 RS16830
gene id: 288004:AL038_RS16830
uniprot id: A0A2N9YDX0
names: Similarity
messages: Belongs to the UPF0434 family.

288004:AL038 RS06835
gene id: 288004:AL038_RS06835
uniprot id: A0A2N9YII0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS16950
gene id: 288004:AL038_RS16950
uniprot id: A0A2N9YDG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

288004:AL038 RS11020
gene id: 288004:AL038_RS11020
uniprot id: A0A2N9YGC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

288004:AL038 RS03300
gene id: 288004:AL038_RS03300
uniprot id: A0A2N9YB91
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

288004:AL038 RS16340
gene id: 288004:AL038_RS16340
uniprot id: A0A2N9YDT7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS14570
gene id: 288004:AL038_RS14570
uniprot id: A0A2N9YJN6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

288004:AL038 RS15630
gene id: 288004:AL038_RS15630
uniprot id: A0A2N9YE49
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

288004:AL038 RS01430
gene id: 288004:AL038_RS01430
uniprot id: A0A2N9YC51
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

288004:AL038 RS01990
gene id: 288004:AL038_RS01990
uniprot id: A0A2N9YBY0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

288004:AL038 RS00470
gene id: 288004:AL038_RS00470
uniprot id: A0A2N9YCN1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS11175
gene id: 288004:AL038_RS11175
uniprot id: A0A2N9YGN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

288004:AL038 RS01555
gene id: 288004:AL038_RS01555
uniprot id: A0A2N9YC33
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

288004:AL038 RS02295
gene id: 288004:AL038_RS02295
uniprot id: A0A2N9YBS1
names: Similarity
messages: Belongs to the UPF0751 family.

288004:AL038 RS17090
gene id: 288004:AL038_RS17090
uniprot id: A0A2N9YJ60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

288004:AL038 RS17295
gene id: 288004:AL038_RS17295
uniprot id: A0A2N9YDA8
names: Similarity
messages: Belongs to the peptidase M1 family.

288004:AL038 RS13480
gene id: 288004:AL038_RS13480
uniprot id: A0A2N9YF91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

288004:AL038 RS03315
gene id: 288004:AL038_RS03315
uniprot id: A0A2N9YB93
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

288004:AL038 RS00800
gene id: 288004:AL038_RS00800
uniprot id: A0A2N9YCG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

288004:AL038 RS06760
gene id: 288004:AL038_RS06760
uniprot id: A0A2N9YIH3
names: Similarity
messages: Belongs to the PhoH family.

288004:AL038 RS02480
gene id: 288004:AL038_RS02480
uniprot id: A0A2N9YBN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

288004:AL038 RS14505
gene id: 288004:AL038_RS14505
uniprot id: A0A2N9YEP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

288004:AL038 RS03490
gene id: 288004:AL038_RS03490
uniprot id: A0A2N9YB99
names: Similarity
messages: Belongs to the GSP E family.

288004:AL038 RS13885
gene id: 288004:AL038_RS13885
uniprot id: A0A2N9YF96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

288004:AL038 RS09115
gene id: 288004:AL038_RS09115
uniprot id: A0A2N9YHE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

288004:AL038 RS12325
gene id: 288004:AL038_RS12325
uniprot id: A0A2N9YG31
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

288004:AL038 RS13045
gene id: 288004:AL038_RS13045
uniprot id: A0A2N9YFG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

288004:AL038 RS01525
gene id: 288004:AL038_RS01525
uniprot id: A0A2N9YC91
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

288004:AL038 RS05915
gene id: 288004:AL038_RS05915
uniprot id: A0A2N9Y9V6
names: Similarity
messages: Belongs to the GARS family.

288004:AL038 RS05615
gene id: 288004:AL038_RS05615
uniprot id: A0A2N9YA18
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

288004:AL038 RS05335
gene id: 288004:AL038_RS05335
uniprot id: A0A2N9YA64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS14495
gene id: 288004:AL038_RS14495
uniprot id: A0A2N9YEP5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

288004:AL038 RS08160
gene id: 288004:AL038_RS08160
uniprot id: A0A2N9YHZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

288004:AL038 RS05575
gene id: 288004:AL038_RS05575
uniprot id: A0A2N9YA33
names: Similarity
messages: Belongs to the GSP E family.

288004:AL038 RS10720
gene id: 288004:AL038_RS10720
uniprot id: A0A2N9YGK9
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

288004:AL038 RS14160
gene id: 288004:AL038_RS14160
uniprot id: A0A2N9YEW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

288004:AL038 RS09600
gene id: 288004:AL038_RS09600
uniprot id: A0A2N9YHG6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

288004:AL038 RS03515
gene id: 288004:AL038_RS03515
uniprot id: A0A2N9YB23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

288004:AL038 RS10610
gene id: 288004:AL038_RS10610
uniprot id: A0A2N9YHE9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

288004:AL038 RS13900
gene id: 288004:AL038_RS13900
uniprot id: A0A2N9YF21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

288004:AL038 RS04075
gene id: 288004:AL038_RS04075
uniprot id: A0A2N9YAT3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS14610
gene id: 288004:AL038_RS14610
uniprot id: A0A2N9YEP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

288004:AL038 RS03320
gene id: 288004:AL038_RS03320
uniprot id: A0A2N9YB70
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

288004:AL038 RS05850
gene id: 288004:AL038_RS05850
uniprot id: A0A2N9Y9X2
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

288004:AL038 RS03665
gene id: 288004:AL038_RS03665
uniprot id: A0A2N9YB72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

288004:AL038 RS09960
gene id: 288004:AL038_RS09960
uniprot id: A0A2N9YGS0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

288004:AL038 RS05230
gene id: 288004:AL038_RS05230
uniprot id: A0A2N9YA77
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS00730
gene id: 288004:AL038_RS00730
uniprot id: A0A650GDY2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

288004:AL038 RS01285
gene id: 288004:AL038_RS01285
uniprot id: A0A2N9YC83
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

288004:AL038 RS10505
gene id: 288004:AL038_RS10505
uniprot id: A0A2N9YH03
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

288004:AL038 RS17900
gene id: 288004:AL038_RS17900
uniprot id: A0A2N9YD45
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

288004:AL038 RS17965
gene id: 288004:AL038_RS17965
uniprot id: A0A2N9YCY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

288004:AL038 RS03775
gene id: 288004:AL038_RS03775
uniprot id: A0A2N9YB28
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

288004:AL038 RS02770
gene id: 288004:AL038_RS02770
uniprot id: A0A2N9YBN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

288004:AL038 RS03120
gene id: 288004:AL038_RS03120
uniprot id: A0A2N9YB90
names: Similarity
messages: Belongs to the bacterial glucokinase family.

288004:AL038 RS16365
gene id: 288004:AL038_RS16365
uniprot id: A0A2N9YDS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

288004:AL038 RS15445
gene id: 288004:AL038_RS15445
uniprot id: A0A2N9YE94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS08515
gene id: 288004:AL038_RS08515
uniprot id: A0A2N9YHI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

288004:AL038 RS12715
gene id: 288004:AL038_RS12715
uniprot id: A0A2N9YGD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Involved in the heme biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
messages: Monomer.

288004:AL038 RS01620
gene id: 288004:AL038_RS01620
uniprot id: A0A2N9YBZ9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

288004:AL038 RS06515
gene id: 288004:AL038_RS06515
uniprot id: A0A2N9YJ44
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

288004:AL038 RS04240
gene id: 288004:AL038_RS04240
uniprot id: A0A2N9YAR2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS17580
gene id: 288004:AL038_RS17580
uniprot id: A0A2N9YD69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

288004:AL038 RS00515
gene id: 288004:AL038_RS00515
uniprot id: A0A2N9YCM5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

288004:AL038 RS02025
gene id: 288004:AL038_RS02025
uniprot id: A0A2N9YBU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

288004:AL038 RS02810
gene id: 288004:AL038_RS02810
uniprot id: A0A2N9YBE9
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

288004:AL038 RS06080
gene id: 288004:AL038_RS06080
uniprot id: A0A2N9YIV2
names: Similarity
messages: Belongs to the YkuD family.

288004:AL038 RS11295
gene id: 288004:AL038_RS11295
uniprot id: A0A2N9YGC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

288004:AL038 RS02190
gene id: 288004:AL038_RS02190
uniprot id: A0A2N9YBR2
names: Similarity
messages: Belongs to the ModE family.

288004:AL038 RS11960
gene id: 288004:AL038_RS11960
uniprot id: A0A2N9YFX5
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS14805
gene id: 288004:AL038_RS14805
uniprot id: A0A2N9YEM1
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

288004:AL038 RS17025
gene id: 288004:AL038_RS17025
uniprot id: A0A2N9YDD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

288004:AL038 RS08225
gene id: 288004:AL038_RS08225
uniprot id: A0A2N9YHP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

288004:AL038 RS05530
gene id: 288004:AL038_RS05530
uniprot id: A0A2N9YA40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS13500
gene id: 288004:AL038_RS13500
uniprot id: A0A2N9YFA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

288004:AL038 RS02900
gene id: 288004:AL038_RS02900
uniprot id: A0A2N9YBJ6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

288004:AL038 RS04350
gene id: 288004:AL038_RS04350
uniprot id: A0A2N9YAQ6
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

288004:AL038 RS17405
gene id: 288004:AL038_RS17405
uniprot id: A0A2N9YDB2
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

288004:AL038 RS01780
gene id: 288004:AL038_RS01780
uniprot id: A0A2N9YC11
names: Similarity
messages: Belongs to the HupH/HyaF family.

288004:AL038 RS06190
gene id: 288004:AL038_RS06190
uniprot id: A0A2N9YIR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

288004:AL038 RS15060
gene id: 288004:AL038_RS15060
uniprot id: A0A2N9YEF0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

288004:AL038 RS00505
gene id: 288004:AL038_RS00505
uniprot id: A0A2N9YCR2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

288004:AL038 RS08090
gene id: 288004:AL038_RS08090
uniprot id: A0A2N9YIP9
names: Similarity
messages: Belongs to the P(II) protein family.

288004:AL038 RS07995
gene id: 288004:AL038_RS07995
uniprot id: A0A650GCR1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

288004:AL038 RS06750
gene id: 288004:AL038_RS06750
uniprot id: A0A2N9YIK6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

288004:AL038 RS10425
gene id: 288004:AL038_RS10425
uniprot id: A0A2N9YGM7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

288004:AL038 RS02515
gene id: 288004:AL038_RS02515
uniprot id: A0A2N9YBP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

288004:AL038 RS11180
gene id: 288004:AL038_RS11180
uniprot id: A0A2N9YGB9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

288004:AL038 RS00045
gene id: 288004:AL038_RS00045
uniprot id: A0A2N9YCW2
names: Similarity
messages: Belongs to the Gram-positive plasmids replication protein type 1 family.

288004:AL038 RS14820
gene id: 288004:AL038_RS14820
uniprot id: A0A2N9YEK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

288004:AL038 RS09695
gene id: 288004:AL038_RS09695
uniprot id: A0A2N9YHE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

288004:AL038 RS00315
gene id: 288004:AL038_RS00315
uniprot id: A0A2N9YCU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

288004:AL038 RS11575
gene id: 288004:AL038_RS11575
uniprot id: A0A2N9YG21
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

288004:AL038 RS08705
gene id: 288004:AL038_RS08705
uniprot id: A0A2N9YHI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS09670
gene id: 288004:AL038_RS09670
uniprot id: A0A2N9YHC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

288004:AL038 RS14200
gene id: 288004:AL038_RS14200
uniprot id: A0A2N9YF11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

288004:AL038 RS04065
gene id: 288004:AL038_RS04065
uniprot id: A0A2N9YAT6
names: Similarity
messages: Belongs to the PspA/IM30 family.

288004:AL038 RS08055
gene id: 288004:AL038_RS08055
uniprot id: A0A2N9YHU1
names: Similarity
messages: Belongs to the Gfa family.

288004:AL038 RS01465
gene id: 288004:AL038_RS01465
uniprot id: A0A2N9YCA4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

288004:AL038 RS07685
gene id: 288004:AL038_RS07685
uniprot id: A0A2N9YIE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

288004:AL038 RS09225
gene id: 288004:AL038_RS09225
uniprot id: A0A2N9YHC4
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS10020
gene id: 288004:AL038_RS10020
uniprot id: A0A2N9YGR0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

288004:AL038 RS16260
gene id: 288004:AL038_RS16260
uniprot id: A0A2N9YE69
names: Subcellular Location Annotation
messages: Cytoplasm

288004:AL038 RS10755
gene id: 288004:AL038_RS10755
uniprot id: A0A2N9YGI7
names: Similarity
messages: Belongs to the FwdC/FmdC family.

288004:AL038 RS08335
gene id: 288004:AL038_RS08335
uniprot id: A0A2N9YI39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

288004:AL038 RS05860
gene id: 288004:AL038_RS05860
uniprot id: A0A2N9Y9X1
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

288004:AL038 RS06975
gene id: 288004:AL038_RS06975
uniprot id: A0A2N9YIG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

288004:AL038 RS17950
gene id: 288004:AL038_RS17950
uniprot id: A0A2N9YD23
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS10300
gene id: 288004:AL038_RS10300
uniprot id: A0A2N9YH20
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

288004:AL038 RS01020
gene id: 288004:AL038_RS01020
uniprot id: A0A2N9YCC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

288004:AL038 RS11025
gene id: 288004:AL038_RS11025
uniprot id: A0A2N9YG67
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

288004:AL038 RS03285
gene id: 288004:AL038_RS03285
uniprot id: A0A2N9YB63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

288004:AL038 RS17535
gene id: 288004:AL038_RS17535
uniprot id: A0A2N9YD81
names: Function
messages: Binds zinc. Could be an important component of the zinc-balancing mechanism.

288004:AL038 RS16660
gene id: 288004:AL038_RS16660
uniprot id: A0A2N9YDL9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

288004:AL038 RS01185
gene id: 288004:AL038_RS01185
uniprot id: A0A650GCB6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

288004:AL038 RS14825
gene id: 288004:AL038_RS14825
uniprot id: A0A2N9YEY1
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS08100
gene id: 288004:AL038_RS08100
uniprot id: A0A2N9YHY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

288004:AL038 RS04045
gene id: 288004:AL038_RS04045
uniprot id: A0A2N9YAV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

288004:AL038 RS09165
gene id: 288004:AL038_RS09165
uniprot id: A0A2N9YHA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

288004:AL038 RS08000
gene id: 288004:AL038_RS08000
uniprot id: A0A2N9YHV1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

288004:AL038 RS13930
gene id: 288004:AL038_RS13930
uniprot id: A0A2N9YF47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

288004:AL038 RS02710
gene id: 288004:AL038_RS02710
uniprot id: A0A2N9YBH5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

288004:AL038 RS16375
gene id: 288004:AL038_RS16375
uniprot id: A0A2N9YDS6
names: Similarity
messages: Belongs to the P(II) protein family.

288004:AL038 RS17060
gene id: 288004:AL038_RS17060
uniprot id: A0A2N9YDH4
names: Similarity
messages: Belongs to the YggT family.

288004:AL038 RS00705
gene id: 288004:AL038_RS00705
uniprot id: A0A2N9YCI7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

288004:AL038 RS16285
gene id: 288004:AL038_RS16285
uniprot id: A0A2N9YDU3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

288004:AL038 RS11155
gene id: 288004:AL038_RS11155
uniprot id: A0A2N9YG94
names: Similarity
messages: Belongs to the ABC transporter superfamily.

288004:AL038 RS17440
gene id: 288004:AL038_RS17440
uniprot id: A0A2N9YDK1
names: Similarity
messages: Belongs to the asparagine synthetase family.

288004:AL038 RS14005
gene id: 288004:AL038_RS14005
uniprot id: A0A2N9YEZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

288004:AL038 RS12495
gene id: 288004:AL038_RS12495
uniprot id: A0A2N9YFK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

288004:AL038 RS06265
gene id: 288004:AL038_RS06265
uniprot id: A0A2N9YIR3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

288004:AL038 RS04030
gene id: 288004:AL038_RS04030
uniprot id: A0A2N9YAW7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

288004:AL038 RS16240
gene id: 288004:AL038_RS16240
uniprot id: A0A0N9M4S5
names: Subcellular Location Annotation
messages: Cytoplasm

288004:AL038 RS16060
gene id: 288004:AL038_RS16060
uniprot id: A0A2N9YDY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

288004:AL038 RS01300
gene id: 288004:AL038_RS01300
uniprot id: A0A2N9YCD0
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

288004:AL038 RS16925
gene id: 288004:AL038_RS16925
uniprot id: A0A2N9YDF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

288004:AL038 RS13940
gene id: 288004:AL038_RS13940
uniprot id: A0A2N9YF16
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

288004:AL038 RS04345
gene id: 288004:AL038_RS04345
uniprot id: A0A2N9YAN9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

288004:AL038 RS13640
gene id: 288004:AL038_RS13640
uniprot id: A0A2N9YFE6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

288004:AL038 RS13635
gene id: 288004:AL038_RS13635
uniprot id: A0A2N9YF97
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

288004:AL038 RS07195
gene id: 288004:AL038_RS07195
uniprot id: A0A2N9YIT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

288004:AL038 RS02690
gene id: 288004:AL038_RS02690
uniprot id: A0A2N9YBI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

288004:AL038 RS13335
gene id: 288004:AL038_RS13335
uniprot id: A0A2N9YFC6
names: Similarity
messages: Belongs to the leucine-binding protein family.

288004:AL038 RS15565
gene id: 288004:AL038_RS15565
uniprot id: A0A2N9YEK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

288004:AL038 RS01600
gene id: 288004:AL038_RS01600
uniprot id: A0A2N9YC37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

288004:AL038 RS18570
gene id: 288004:AL038_RS18570
uniprot id: A0A2N9YG09
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

288004:AL038 RS00545
gene id: 288004:AL038_RS00545
uniprot id: A0A2N9YJB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

288004:AL038 RS13945
gene id: 288004:AL038_RS13945
uniprot id: A0A2N9YF08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

288004:AL038 RS17345
gene id: 288004:AL038_RS17345
uniprot id: A0A2N9YD98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

288004:AL038 RS15350
gene id: 288004:AL038_RS15350
uniprot id: A0A2N9YEB3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

288004:AL038 RS06705
gene id: 288004:AL038_RS06705
uniprot id: A0A2N9YIL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

288004:AL038 RS13210
gene id: 288004:AL038_RS13210
uniprot id: A0A2N9YFD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

288004:AL038 RS03365
gene id: 288004:AL038_RS03365
uniprot id: A0A2N9YB67
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

288004:AL038 RS00535
gene id: 288004:AL038_RS00535
uniprot id: A0A2N9YCL0
names: Similarity
messages: Belongs to the SCO1/2 family.

288004:AL038 RS04450
gene id: 288004:AL038_RS04450
uniprot id: A0A2N9YAN2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

288004:AL038 RS11795
gene id: 288004:AL038_RS11795
uniprot id: A0A2N9YG00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

288004:AL038 RS16050
gene id: 288004:AL038_RS16050
uniprot id: A0A2N9YEB2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

288004:AL038 RS01995
gene id: 288004:AL038_RS01995
uniprot id: A0A2N9YBX6
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

288004:AL038 RS15535
gene id: 288004:AL038_RS15535
uniprot id: A0A2N9YE93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

288004:AL038 RS12705
gene id: 288004:AL038_RS12705
uniprot id: A0A2N9YFK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

288004:AL038 RS08240
gene id: 288004:AL038_RS08240
uniprot id: A0A2N9YI38
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

288004:AL038 RS08345
gene id: 288004:AL038_RS08345
uniprot id: A0A2N9YHW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

288004:AL038 RS02030
gene id: 288004:AL038_RS02030
uniprot id: A0A2N9YJ23
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

288004:AL038 RS13125
gene id: 288004:AL038_RS13125
uniprot id: A0A2N9YFR8
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

288004:AL038 RS14060
gene id: 288004:AL038_RS14060
uniprot id: A0A2N9YEY3
names: Subcellular Location Annotation
messages: Membrane

288004:AL038 RS00885
gene id: 288004:AL038_RS00885
uniprot id: A0A2N9YCF9
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

288004:AL038 RS00300
gene id: 288004:AL038_RS00300
uniprot id: A0A2N9YCU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS03800
gene id: 288004:AL038_RS03800
uniprot id: A0A2N9YJ10
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-II family.

288004:AL038 RS02910
gene id: 288004:AL038_RS02910
uniprot id: A0A2N9YBD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

288004:AL038 RS00620
gene id: 288004:AL038_RS00620
uniprot id: A0A2N9YCK1
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

288004:AL038 RS18055
gene id: 288004:AL038_RS18055
uniprot id: A0A2N9YCZ5
names: Similarity
messages: Belongs to the citrate synthase family.

288004:AL038 RS14945
gene id: 288004:AL038_RS14945
uniprot id: A0A2N9YJ76
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS07235
gene id: 288004:AL038_RS07235
uniprot id: A0A2N9YI88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS06945
gene id: 288004:AL038_RS06945
uniprot id: A0A2N9YIF3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

288004:AL038 RS03305
gene id: 288004:AL038_RS03305
uniprot id: A0A2N9YB66
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

288004:AL038 RS12795
gene id: 288004:AL038_RS12795
uniprot id: A0A2N9YFK3
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

288004:AL038 RS01725
gene id: 288004:AL038_RS01725
uniprot id: A0A2N9YC21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

288004:AL038 RS06165
gene id: 288004:AL038_RS06165
uniprot id: A0A2N9YJJ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS18095
gene id: 288004:AL038_RS18095
uniprot id: A0A2N9YCY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

288004:AL038 RS14330
gene id: 288004:AL038_RS14330
uniprot id: A0A2N9YEU6
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

288004:AL038 RS08715
gene id: 288004:AL038_RS08715
uniprot id: A0A2N9YHF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

288004:AL038 RS00385
gene id: 288004:AL038_RS00385
uniprot id: A0A2N9YCR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

288004:AL038 RS14785
gene id: 288004:AL038_RS14785
uniprot id: A0A2N9YEJ5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS07625
gene id: 288004:AL038_RS07625
uniprot id: A0A2N9YI11
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

288004:AL038 RS17385
gene id: 288004:AL038_RS17385
uniprot id: A0A2N9YDL1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

288004:AL038 RS01885
gene id: 288004:AL038_RS01885
uniprot id: A0A2N9YBZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

288004:AL038 RS11220
gene id: 288004:AL038_RS11220
uniprot id: A0A2N9YGB6
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

288004:AL038 RS13890
gene id: 288004:AL038_RS13890
uniprot id: A0A2N9YF26
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

288004:AL038 RS04825
gene id: 288004:AL038_RS04825
uniprot id: A0A2N9YAG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

288004:AL038 RS14170
gene id: 288004:AL038_RS14170
uniprot id: A0A2N9YJ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

288004:AL038 RS16905
gene id: 288004:AL038_RS16905
uniprot id: A0A2N9YDU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

288004:AL038 RS17520
gene id: 288004:AL038_RS17520
uniprot id: A0A2N9YD56
names: Similarity
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.

288004:AL038 RS06815
gene id: 288004:AL038_RS06815
uniprot id: A0A2N9YID7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

288004:AL038 RS09995
gene id: 288004:AL038_RS09995
uniprot id: A0A2N9YHR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

288004:AL038 RS06810
gene id: 288004:AL038_RS06810
uniprot id: A0A2N9YIG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

288004:AL038 RS09585
gene id: 288004:AL038_RS09585
uniprot id: A0A2N9YH32
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

288004:AL038 RS08540
gene id: 288004:AL038_RS08540
uniprot id: A0A2N9YHZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

288004:AL038 RS09020
gene id: 288004:AL038_RS09020
uniprot id: A0A2N9YI93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

288004:AL038 RS04300
gene id: 288004:AL038_RS04300
uniprot id: A0A2N9YAR5
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

288004:AL038 RS06335
gene id: 288004:AL038_RS06335
uniprot id: A0A2N9YIS5
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

288004:AL038 RS07930
gene id: 288004:AL038_RS07930
uniprot id: A0A2N9YI29
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

288004:AL038 RS04855
gene id: 288004:AL038_RS04855
uniprot id: A0A2N9YAE4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

288004:AL038 RS15655
gene id: 288004:AL038_RS15655
uniprot id: A0A2N9YE96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

288004:AL038 RS08590
gene id: 288004:AL038_RS08590
uniprot id: A0A2N9YHH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

288004:AL038 RS03045
gene id: 288004:AL038_RS03045
uniprot id: A0A2N9YBC6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.