284813:ECU02 0920
gene id: 284813:ECU02_0920
uniprot id: Q8SWC6
names: Similarity
messages: Belongs to the MAD1 family.

284813:ECU01 1130
gene id: 284813:ECU01_1130
uniprot id: Q8SQJ3
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Expression is low in meronts, but becomes induced in sporonts and spores.
messages: May be involved in the degradation of proteins for nutrient acquisition or possess a regulatory function by proteolytic activation of proproteins.
messages: extracellular space

284813:ECU11 2110
gene id: 284813:ECU11_2110
uniprot id: Q8STZ0
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU10 1700i
gene id: 284813:ECU10_1700i
uniprot id: Q8SR00
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

284813:ECU06 0100
gene id: 284813:ECU06_0100
uniprot id: Q8SVF2
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU06 1510
gene id: 284813:ECU06_1510
uniprot id: Q8SV69
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

284813:ECU02 1550
gene id: 284813:ECU02_1550
uniprot id: Q8ST67
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU03 0820i
gene id: 284813:ECU03_0820i
uniprot id: Q8SS99
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Expressed in late sporogonial stages.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

284813:ECU09 1330
gene id: 284813:ECU09_1330
uniprot id: Q8SQM0
names: Developmental Stage
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the activator 1 small subunits family.
messages: Component of ATP-dependent clamp loader (RFC and RFC-like) complexes for DNA clamps. During a clamp loading circle, the RFC:clamp complex binds to DNA and the recognition of the double-stranded/single-stranded junction stimulates ATP hydrolysis by RFC. The complex presumably provides bipartite ATP sites in which one subunit supplies a catalytic site for hydrolysis of ATP bound to the neighboring subunit. Dissociation of RFC from the clamp leaves the clamp encircling DNA. Component of the replication factor C (RFC or activator 1) complex which acts during elongation of primed DNA templates by DNA polymerase delta and epsilon. RFC has an essential but redundant activity in sister chromatid cohesion establishment (By similarity).
messages: Component of the replication factor C (RFC) complex.
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: Present with 2760 molecules/cell in log phase SD medium.

284813:ECU07 0010
gene id: 284813:ECU07_0010
uniprot id: P0CT03
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU06 1290
gene id: 284813:ECU06_1290
uniprot id: Q8SV84
names: Subcellular Location Annotation
messages: Membrane

284813:ECU09 0020
gene id: 284813:ECU09_0020
uniprot id: Q8STY8
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU06 0260
gene id: 284813:ECU06_0260
uniprot id: Q8SRS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

284813:ECU11 1400
gene id: 284813:ECU11_1400
uniprot id: Q8SQU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template. Involved in the regulation of transcription elongation (By similarity).
messages: nucleolus

284813:ECU08 0110
gene id: 284813:ECU08_0110
uniprot id: Q8SRG1
names: Subcellular Location Annotation
messages: Membrane

284813:ECU04 0310
gene id: 284813:ECU04_0310
uniprot id: Q8SS65
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a regulatory subunit of the 26S proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH (By similarity).
messages: Belongs to the proteasome subunit S2 family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel (By similarity).

284813:ECU04 1110
gene id: 284813:ECU04_1110
uniprot id: Q8SVS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOP6A family.
messages: Nucleus
messages: Required for meiotic recombination. Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination (By similarity).

284813:ECU01 0120
gene id: 284813:ECU01_0120
uniprot id: Q8STB3
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU03 0090
gene id: 284813:ECU03_0090
uniprot id: Q8SW78
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU08 0800
gene id: 284813:ECU08_0800
uniprot id: Q8SRC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Fungal signal recognition particle consists of a 7S RNA molecule (scR1) and at least six protein subunits: SRP72, SRP68, SRP54, SEC65, SRP21 and SRP14.
messages: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. It must be involved intimately in the translocation of a wide variety of protein substrates (By similarity).

284813:ECU06 0490
gene id: 284813:ECU06_0490
uniprot id: Q8SRR7
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

284813:ECU11 0790
gene id: 284813:ECU11_0790
uniprot id: Q8SQX2
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the COPII coat.
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Expressed in late sporogonial stages.
messages: Golgi apparatus membrane

284813:ECU04 0080
gene id: 284813:ECU04_0080
uniprot id: Q8ST97
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU10 0660
gene id: 284813:ECU10_0660
uniprot id: Q8SR51
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

284813:ECU08 0860
gene id: 284813:ECU08_0860
uniprot id: Q8SRC0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284813:ECU08 1300
gene id: 284813:ECU08_1300
uniprot id: Q8SRA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP transporter involved in the uptake of ATP from the host cell cytoplasm. Provides the microsporidian cell with host ATP in exchange for ADP. This is an obligate exchange system. This energy acquiring activity is an important component of microsporidian parasitism.
messages: Belongs to the ADP/ATP translocase tlc family.
messages: Cell membrane

284813:ECU11 0970
gene id: 284813:ECU11_0970
uniprot id: Q8SU45
names: Similarity
messages: Belongs to the DCP1 family.

284813:ECU01 1350
gene id: 284813:ECU01_1350
uniprot id: Q8SWI1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

284813:ECU04 1630
gene id: 284813:ECU04_1630
uniprot id: Q8SVP6
names: Subcellular Location Annotation
messages: Membrane

284813:ECU02 1270
gene id: 284813:ECU02_1270
uniprot id: Q8SSE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis.
messages: Nucleus

284813:ECU07 0560
gene id: 284813:ECU07_0560
uniprot id: Q8SRK7
names: Subcellular Location Annotation
messages: Membrane

284813:ECU07 1280
gene id: 284813:ECU07_1280
uniprot id: Q8SRI2
names: Developmental Stage
names: Function
messages: Expressed in late sporogonial stages.
messages: Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).

284813:ECU03 0010
gene id: 284813:ECU03_0010
uniprot id: Q8SW85
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU10 1410
gene id: 284813:ECU10_1410
uniprot id: Q8SUB9
names: Subcellular Location Annotation
messages: Membrane

284813:ECU08 1970
gene id: 284813:ECU08_1970
uniprot id: Q8SQI9
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a regulatory subunit of the 26S proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH (By similarity).
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel (By similarity).

284813:ECU09 1970
gene id: 284813:ECU09_1970
uniprot id: Q8SQJ4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

284813:ECU08 1820
gene id: 284813:ECU08_1820
uniprot id: Q8SUJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus

284813:ECU02 1130
gene id: 284813:ECU02_1130
uniprot id: Q8SSE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: Nucleus
messages: Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Recruited to DNA lesions in order to initiate the DNA repair by homologous recombination. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, also involved in the regulation of DNA damage response mechanism. Required for cell growth and meiotic recombination (By similarity).

284813:ECU10 0070
gene id: 284813:ECU10_0070
uniprot id: Q8ST62
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Component of the large ribosomal subunit.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU07 0370
gene id: 284813:ECU07_0370
uniprot id: Q8SV34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Membrane

284813:ECU05 0270
gene id: 284813:ECU05_0270
uniprot id: Q8SS04
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

284813:ECU08 1070
gene id: 284813:ECU08_1070
uniprot id: Q8STD9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

284813:ECU10 1430
gene id: 284813:ECU10_1430
uniprot id: Q8SR12
names: Similarity
messages: Belongs to the acetyltransferase family. GCN5 subfamily.

284813:ECU02 0740i
gene id: 284813:ECU02_0740i
uniprot id: Q8SWD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family.
messages: Cytoplasm
messages: Nucleus
messages: Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, and DNA-damage responses. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).

284813:ECU11 1600
gene id: 284813:ECU11_1600
uniprot id: Q8SU14
names: Similarity
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.

284813:ECU06 0650
gene id: 284813:ECU06_0650
uniprot id: Q8SVC2
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Monomer.

284813:ECU08 0280
gene id: 284813:ECU08_0280
uniprot id: Q8SRF1
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Non-catalytic component of the proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity (By similarity).
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel (By similarity).

284813:ECU08 1500
gene id: 284813:ECU08_1500
uniprot id: Q8SUL8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

284813:ECU07 0540
gene id: 284813:ECU07_0540
uniprot id: Q8SV24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

284813:ECU10 1130
gene id: 284813:ECU10_1130
uniprot id: Q8SR28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

284813:ECU06 1670
gene id: 284813:ECU06_1670
uniprot id: Q8SV58
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU02 0050
gene id: 284813:ECU02_0050
uniprot id: Q8SWH7
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU07 0760
gene id: 284813:ECU07_0760
uniprot id: Q8SRK0
names: Cofactor
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Homodimer.
messages: Probably involved in mitosomal protein import.

284813:ECU03 1620
gene id: 284813:ECU03_1620
uniprot id: Q8SVY8
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU10 0310
gene id: 284813:ECU10_0310
uniprot id: Q8SR70
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

284813:ECU01 1370
gene id: 284813:ECU01_1370
uniprot id: Q8SSI8
names: Developmental Stage
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Component of the septin complex.
messages: Expressed in late sporogonial stages.
messages: Septins are GTPases involved in cytokinesis. The septins localize to the site of cleavage and act as a structural scaffold that recruits different components involved in diverse processes at specific stages during the cell cycle. Septins are also involved in cell morphogenesis, chitin deposition, cell cycle regulation, cell compartmentalization and spore wall formation (By similarity).

284813:ECU09 0330
gene id: 284813:ECU09_0330
uniprot id: Q8SQP9
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel (By similarity).
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity (By similarity).

284813:ECU11 1520
gene id: 284813:ECU11_1520
uniprot id: Q8SU19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with TRM82.
messages: Nucleus

284813:ECU07 1320
gene id: 284813:ECU07_1320
uniprot id: Q8SUX1
names: Similarity
messages: Belongs to the RMD1/sif2 family.

284813:ECU03 1330
gene id: 284813:ECU03_1330
uniprot id: Q8SS82
names: Similarity
messages: Belongs to the AAA ATPase family.

284813:ECU05 1640
gene id: 284813:ECU05_1640
uniprot id: Q8STF1
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU01 1480
gene id: 284813:ECU01_1480
uniprot id: Q8ST53
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU03 1050
gene id: 284813:ECU03_1050
uniprot id: Q8SW25
names: Subcellular Location Annotation
messages: Membrane

284813:ECU01 0740i
gene id: 284813:ECU01_0740i
uniprot id: O96720
names: Similarity
messages: Belongs to the thymidine kinase family.

284813:ECU03 1000
gene id: 284813:ECU03_1000
uniprot id: Q8SW29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

284813:ECU07 1570
gene id: 284813:ECU07_1570
uniprot id: Q8SRH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

284813:ECU02 0450
gene id: 284813:ECU02_0450
uniprot id: Q8SSH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.

284813:ECU01 1500
gene id: 284813:ECU01_1500
uniprot id: Q8STB5
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU01 0080
gene id: 284813:ECU01_0080
uniprot id: Q8STE0
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU06 1360
gene id: 284813:ECU06_1360
uniprot id: Q8SRN6
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

284813:ECU03 1610
gene id: 284813:ECU03_1610
uniprot id: Q8SVY9
names: Developmental Stage
names: Similarity
messages: Belongs to the LEA type 1 family.
messages: Expressed in late sporogonial stages.

284813:ECU11 2030
gene id: 284813:ECU11_2030
uniprot id: Q8SQQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STE12 transcription factor family.
messages: Nucleus

284813:ECU06 1230
gene id: 284813:ECU06_1230
uniprot id: Q8SV88
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

284813:ECU02 0720
gene id: 284813:ECU02_0720
uniprot id: Q8SSG3
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

284813:ECU09 0100
gene id: 284813:ECU09_0100
uniprot id: Q8STY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

284813:ECU09 1310
gene id: 284813:ECU09_1310
uniprot id: Q8SQM1
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

284813:ECU05 1270
gene id: 284813:ECU05_1270
uniprot id: Q8SRV1
names: Similarity
messages: Belongs to the DEAD box helicase family.

284813:ECU09 1000
gene id: 284813:ECU09_1000
uniprot id: Q8SQI3
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU03 1360
gene id: 284813:ECU03_1360
uniprot id: Q8SW07
names: Similarity
messages: Belongs to the MYG1 family.

284813:ECU09 0940
gene id: 284813:ECU09_0940
uniprot id: Q8SQN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.

284813:ECU01 1420
gene id: 284813:ECU01_1420
uniprot id: O62585
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Cytoplasm
messages: Homotetramer.
messages: Interconversion of serine and glycine.

284813:ECU05 1650
gene id: 284813:ECU05_1650
uniprot id: P0CT00
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU03 0840
gene id: 284813:ECU03_0840
uniprot id: Q8SW39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

284813:ECU08 1120
gene id: 284813:ECU08_1120
uniprot id: Q8SRA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
messages: Nucleus

284813:ECU11 1260
gene id: 284813:ECU11_1260
uniprot id: Q8SQV0
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

284813:ECU08 0350i
gene id: 284813:ECU08_0350i
uniprot id: Q8SRE7
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

284813:ECU05 1060
gene id: 284813:ECU05_1060
uniprot id: Q8SRV8
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU01 1470
gene id: 284813:ECU01_1470
uniprot id: Q8SQI6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

284813:ECU02 0460
gene id: 284813:ECU02_0460
uniprot id: Q8SWE7
names: Subcellular Location Annotation
messages: nuclear pore complex

284813:ECU06 0770
gene id: 284813:ECU06_0770
uniprot id: Q8SRQ9
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

284813:ECU04 1020
gene id: 284813:ECU04_1020
uniprot id: Q8SS33
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Component of the T-complex protein 1 (TCP1) complex.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.

284813:ECU08 2080
gene id: 284813:ECU08_2080
uniprot id: Q8SUH8
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU08 2070
gene id: 284813:ECU08_2070
uniprot id: Q8SUH9
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU05 0590
gene id: 284813:ECU05_0590
uniprot id: Q8SVK8
names: Developmental Stage
messages: Expressed in late sporogonial stages.

284813:ECU02 0530
gene id: 284813:ECU02_0530
uniprot id: Q8SWE3
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU03 0470
gene id: 284813:ECU03_0470
uniprot id: Q8SSB5
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

284813:ECU10 0640
gene id: 284813:ECU10_0640
uniprot id: Q8SR52
names: Similarity
messages: Belongs to the dynein heavy chain family.

284813:ECU11 0840
gene id: 284813:ECU11_0840
uniprot id: Q8SQW9
names: Similarity
messages: Belongs to the AAA ATPase family.

284813:ECU07 0880
gene id: 284813:ECU07_0880
uniprot id: Q8SV04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

284813:ECU11 0800
gene id: 284813:ECU11_0800
uniprot id: Q8SQX1
names: Similarity
messages: Belongs to the MCM family.

284813:ECU09 0390
gene id: 284813:ECU09_0390
uniprot id: Q8STV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

284813:ECU01 0920
gene id: 284813:ECU01_0920
uniprot id: Q8SSK9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

284813:ECU05 1130
gene id: 284813:ECU05_1130
uniprot id: Q8SVI2
names: Similarity
messages: Belongs to the Clp1 family. NOL9/GRC3 subfamily.

284813:ECU08 0490
gene id: 284813:ECU08_0490
uniprot id: Q8SRE0
names: Cofactor
names: Developmental Stage
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Expressed in late sporogonial stages.

284813:ECU08 1250
gene id: 284813:ECU08_1250
uniprot id: Q8SRA6
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

284813:ECU06 0320
gene id: 284813:ECU06_0320
uniprot id: Q8SRS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of 14, 12 and 17 subunits, respectively.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, RBP10 is part of the core element with the central large cleft (By similarity).
messages: Nucleus

284813:ECU05 1660
gene id: 284813:ECU05_1660
uniprot id: Q8STG4
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU09 0760
gene id: 284813:ECU09_0760
uniprot id: Q8SQN6
names: Function
messages: Possesses 5'->3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote termination of transcription by RNA polymerase II.

284813:ECU03 0710
gene id: 284813:ECU03_0710
uniprot id: Q8SSA2
names: Developmental Stage
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.
messages: Expressed in late sporogonial stages.

284813:ECU03 0150
gene id: 284813:ECU03_0150
uniprot id: Q8SSD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TPT transporter family. SLC35D subfamily.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homooligomer.
messages: Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
messages: Membrane

284813:ECU04 1250
gene id: 284813:ECU04_1250
uniprot id: Q8SS21
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

284813:ECU05 0990
gene id: 284813:ECU05_0990
uniprot id: Q8SRW2
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

284813:ECU04 1660
gene id: 284813:ECU04_1660
uniprot id: Q8SVP3
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU07 1860
gene id: 284813:ECU07_1860
uniprot id: Q8ST89
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU06 1710
gene id: 284813:ECU06_1710
uniprot id: Q8STE8
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU07 0650
gene id: 284813:ECU07_0650
uniprot id: Q8SV15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284813:ECU05 1430
gene id: 284813:ECU05_1430
uniprot id: Q8SVG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

284813:ECU07 1090
gene id: 284813:ECU07_1090
uniprot id: Q8SUY7
names: Developmental Stage
messages: Expressed in late sporogonial stages.

284813:ECU10 0590
gene id: 284813:ECU10_0590
uniprot id: Q8SR56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PI3/PI4-kinase family.
messages: Component of the autophagy-specific VPS34 PI3-kinase complex I composed; and of the VPS34 PI3-kinase complex II.
messages: Endosome membrane
messages: Phosphatidylinositol 3-kinase required for cytoplasm to vacuole transport (Cvt) and autophagy as a part of the autophagy-specific VPS34 PI3-kinase complex I. Also involved in endosome-to-Golgi retrograde transport as part of the VPS34 PI3-kinase complex II (By similarity).
messages: trans-Golgi network membrane

284813:ECU11 0270
gene id: 284813:ECU11_0270
uniprot id: Q8SU83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

284813:ECU01 1360
gene id: 284813:ECU01_1360
uniprot id: O96722
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA.
messages: nucleolus

284813:ECU03 0390
gene id: 284813:ECU03_0390
uniprot id: Q8SSB8
names: Subcellular Location Annotation
messages: Membrane

284813:ECU11 1390
gene id: 284813:ECU11_1390
uniprot id: Q8SU23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

284813:ECU09 1690
gene id: 284813:ECU09_1690
uniprot id: Q8SQK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NUF2 family.
messages: Component of the NDC80 complex, which consists of at least NDC80 and NUF2.
messages: Nucleus
messages: kinetochore

284813:ECU08 0400
gene id: 284813:ECU08_0400
uniprot id: Q8SRE3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

284813:ECU11 1240
gene id: 284813:ECU11_1240
uniprot id: Q8SU29
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU10 1820
gene id: 284813:ECU10_1820
uniprot id: Q8SU95
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU06 0480
gene id: 284813:ECU06_0480
uniprot id: Q8SVD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

284813:ECU09 0480
gene id: 284813:ECU09_0480
uniprot id: Q8SQP2
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Component of the T-complex protein 1 (TCP1) complex.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.

284813:ECU05 1120i
gene id: 284813:ECU05_1120i
uniprot id: Q8SRV7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

284813:ECU06 0400
gene id: 284813:ECU06_0400
uniprot id: Q8SVD9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Cytoplasm
messages: Nucleus
messages: This protein is considered an atypical serine/threonine kinase, because it lacks the conventional structural elements necessary for the substrate recognition as well as a lysine residue that in all other serine/threonine kinases participates in the catalytic event (By similarity). BUD32 has protein kinase activity in vitro, but in the context of the EKC/KEOPS complex, the catalytic subunit KAE1 switches the activity of BUD32 from kinase into ATPase (By similarity).
messages: telomere

284813:ECU06 1410
gene id: 284813:ECU06_1410
uniprot id: Q8SV74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

284813:ECU06 1445
gene id: 284813:ECU06_1445
uniprot id: Q8SRN2
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS26 family.
messages: Component of the small ribosomal subunit.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU07 0180
gene id: 284813:ECU07_0180
uniprot id: Q8SQJ1
names: Similarity
messages: Belongs to the histidine acid phosphatase family.

284813:ECU08 0320
gene id: 284813:ECU08_0320
uniprot id: Q8SRE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Nucleus

284813:ECU08 1380
gene id: 284813:ECU08_1380
uniprot id: Q8SUM8
names: Caution
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutaredoxin family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity).
messages: May be inactive since it lacks one cysteine involved the redox-active disulfide bond.

284813:ECU07 1760
gene id: 284813:ECU07_1760
uniprot id: Q8SRG4
names: Similarity
messages: Belongs to the acetyltransferase family. GNA1 subfamily.

284813:ECU03 1600
gene id: 284813:ECU03_1600
uniprot id: Q8SVZ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YAF9 family.
messages: Component of the SWR1 chromatin-remodeling complex and of the NuA4 histone acetyltransferase complex.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for an H2A variant leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised.
messages: Cytoplasm
messages: Nucleus
messages: The coiled-coil domain is required for assembly into the NuA4 complex.

284813:ECU10 0040
gene id: 284813:ECU10_0040
uniprot id: Q8ST89
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU01 0600
gene id: 284813:ECU01_0600
uniprot id: Q8SSL9
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

284813:ECU05 0600
gene id: 284813:ECU05_0600
uniprot id: Q8SRY5
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Component of the large ribosomal subunit.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU11 1210
gene id: 284813:ECU11_1210
uniprot id: Q8SU32
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWP7 family.
messages: Expressed in late sporogonial stages.
messages: Spore wall

284813:ECU09 0250
gene id: 284813:ECU09_0250
uniprot id: Q8STX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

284813:ECU11 1990
gene id: 284813:ECU11_1990
uniprot id: Q8SQR1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284813:ECU02 0580
gene id: 284813:ECU02_0580
uniprot id: Q8SSH0
names: Cofactor
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

284813:ECU06 1690
gene id: 284813:ECU06_1690
uniprot id: Q8STJ4
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU09 1380
gene id: 284813:ECU09_1380
uniprot id: Q8SQL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

284813:ECU04 0530
gene id: 284813:ECU04_0530
uniprot id: Q8SVW0
names: Similarity
messages: Belongs to the HSF family.

284813:ECU07 0490
gene id: 284813:ECU07_0490
uniprot id: Q8SRK9
names: Similarity
messages: Belongs to the MCM family.

284813:ECU06 0500
gene id: 284813:ECU06_0500
uniprot id: Q8SVD3
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU08 1870
gene id: 284813:ECU08_1870
uniprot id: Q8SR88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

284813:ECU05 0860
gene id: 284813:ECU05_0860
uniprot id: Q8SRX1
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

284813:ECU04 1140
gene id: 284813:ECU04_1140
uniprot id: Q8SS27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

284813:ECU11 0830
gene id: 284813:ECU11_0830
uniprot id: Q8SU50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Nucleus

284813:ECU06 0270
gene id: 284813:ECU06_0270
uniprot id: Q8SVE4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

284813:ECU06 1490
gene id: 284813:ECU06_1490
uniprot id: Q8SV71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
messages: Cytoplasm
messages: Nucleus

284813:ECU10 1120
gene id: 284813:ECU10_1120
uniprot id: Q8SR29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

284813:ECU11 0850
gene id: 284813:ECU11_0850
uniprot id: Q8SQW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

284813:ECU08 0600i
gene id: 284813:ECU08_0600i
uniprot id: Q8SRD7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

284813:ECU03 0520
gene id: 284813:ECU03_0520
uniprot id: Q8SSB1
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU05 1500
gene id: 284813:ECU05_1500
uniprot id: Q8SVG2
names: Subcellular Location Annotation
messages: nucleolus

284813:ECU11 0180
gene id: 284813:ECU11_0180
uniprot id: Q8SQZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.
messages: Cytoplasm
messages: Negative regulator of the cell cycle acting downstream of the cAMP-dependent protein kinase. Part of a glucose-sensing system involved in growth control in response to glucose availability (By similarity).
messages: Nucleus

284813:ECU03 0610
gene id: 284813:ECU03_0610
uniprot id: Q8SW50
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU11 0280
gene id: 284813:ECU11_0280
uniprot id: Q8SU82
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU11 1170
gene id: 284813:ECU11_1170
uniprot id: Q8SU33
names: Subcellular Location Annotation
messages: nucleolus

284813:ECU09 1860
gene id: 284813:ECU09_1860
uniprot id: Q8STL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

284813:ECU07 0380
gene id: 284813:ECU07_0380
uniprot id: Q8SRL4
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

284813:ECU06 0010
gene id: 284813:ECU06_0010
uniprot id: Q8STE8
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU11 1280i
gene id: 284813:ECU11_1280i
uniprot id: Q8SQU9
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity).
messages: Endomembrane system
messages: Expressed in late sporogonial stages.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1).
messages: Vacuole membrane

284813:ECU06 1620
gene id: 284813:ECU06_1620
uniprot id: Q8SV63
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU04 1190
gene id: 284813:ECU04_1190
uniprot id: Q8SVS6
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

284813:ECU05 1440
gene id: 284813:ECU05_1440
uniprot id: Q8SRU2
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: Plays a role in splicing.

284813:ECU03 0110
gene id: 284813:ECU03_0110
uniprot id: Q8SW76
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU04 1100
gene id: 284813:ECU04_1100
uniprot id: Q8SS29
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Component of the eukaryotic elongation factor 1 complex (eEF1).
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: GTP-binding component of the eukaryotic elongation factor 1 complex (eEF1). In its active GTP-bound form, binds to and delivers aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. In the presence of a correct codon-anticodon match between the aminoacyl-tRNA and the A-site codon of the ribosome-bound mRNA, the ribosome acts as a GTPase activator and the GTP is hydrolyzed. The inactive GDP-bound form leaves the ribosome and must be recycled by its guanine nucleotide exchange factor (GEF) (eEF1B subcomplex) before binding another molecule of aminoacyl-tRNA. Required for nuclear export of aminoacyl-tRNAs. May also be involved in translational quality control by targeting cotranslationally damaged proteins to the proteasome (By similarity).

284813:ECU06 0430
gene id: 284813:ECU06_0430
uniprot id: Q8SRS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dUTPase family.
messages: Homotrimer.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

284813:ECU02 0550
gene id: 284813:ECU02_0550
uniprot id: Q8SSH1
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

284813:ECU01 0140
gene id: 284813:ECU01_0140
uniprot id: Q8SQI6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

284813:ECU05 1530
gene id: 284813:ECU05_1530
uniprot id: Q8SRT8
names: Similarity
messages: Belongs to the activator 1 large subunit family.

284813:ECU05 0080
gene id: 284813:ECU05_0080
uniprot id: Q8SVN7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

284813:ECU07 1790
gene id: 284813:ECU07_1790
uniprot id: Q8SUU4
names: Similarity
messages: Belongs to the MYG1 family.

284813:ECU06 1250
gene id: 284813:ECU06_1250
uniprot id: Q8SRN8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284813:ECU09 0395
gene id: 284813:ECU09_0395
uniprot id: Q8SQP8
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL39 family.
messages: Interacts with YIH1.

284813:ECU09 0010
gene id: 284813:ECU09_0010
uniprot id: Q8STY9
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU03 0300
gene id: 284813:ECU03_0300
uniprot id: Q8SW66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.

284813:ECU07 0740
gene id: 284813:ECU07_0740
uniprot id: Q8SRK2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA). In microsporidia, the second signature motif differs slightly and is Asn-Pro-Gly (NPG).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Water channel required to facilitate the transport of water across membranes. Involved in osmotolerance.

284813:ECU02 1160
gene id: 284813:ECU02_1160
uniprot id: Q8SWB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

284813:ECU01 1080
gene id: 284813:ECU01_1080
uniprot id: Q8SSK0
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284813:ECU04 1700
gene id: 284813:ECU04_1700
uniprot id: Q8ST35
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU04 1240
gene id: 284813:ECU04_1240
uniprot id: Q8SVS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

284813:ECU10 1110
gene id: 284813:ECU10_1110
uniprot id: Q8SR30
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Nucleus

284813:ECU11 1430
gene id: 284813:ECU11_1430
uniprot id: Q8SQT9
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

284813:ECU08 0850
gene id: 284813:ECU08_0850
uniprot id: Q8SUQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

284813:ECU01 0200
gene id: 284813:ECU01_0200
uniprot id: Q8SQI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
messages: Membrane

284813:ECU04 0110
gene id: 284813:ECU04_0110
uniprot id: Q8SVY5
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU06 0090
gene id: 284813:ECU06_0090
uniprot id: Q8SVF3
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU06 0340
gene id: 284813:ECU06_0340
uniprot id: Q8SRS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

284813:ECU05 1510
gene id: 284813:ECU05_1510
uniprot id: Q8SRU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.
messages: Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer composed of two alpha chains, one beta chain and one beta' chain.

284813:ECU11 1970
gene id: 284813:ECU11_1970
uniprot id: Q8STZ5
names: Similarity
messages: Belongs to the WD repeat PRL1/PRL2 family.

284813:ECU02 1250
gene id: 284813:ECU02_1250
uniprot id: Q8SSE1
names: Similarity
messages: Belongs to the TAF11 family.

284813:ECU10 1810
gene id: 284813:ECU10_1810
uniprot id: Q8SU96
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU04 1220
gene id: 284813:ECU04_1220
uniprot id: Q8SS22
names: Similarity
messages: Belongs to the thymidylate kinase family.

284813:ECU09 1190
gene id: 284813:ECU09_1190
uniprot id: Q8SQM6
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

284813:ECU07 0090
gene id: 284813:ECU07_0090
uniprot id: Q8SRM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

284813:ECU07 0190
gene id: 284813:ECU07_0190
uniprot id: Q8SRM0
names: Similarity
messages: Belongs to the AAA ATPase family.

284813:ECU11 0960
gene id: 284813:ECU11_0960
uniprot id: Q8SQW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
messages: Catalytic subunit of the CTDK-I complex, which hyperphosphorylates the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit. Involved in RNA polymerase II transcriptional elongation and pre-mRNA 3'-end processing (By similarity).
messages: Component of the CTDK-I complex.
messages: nucleolus

284813:ECU07 1270
gene id: 284813:ECU07_1270
uniprot id: Q8SRI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
messages: Cytoplasm
messages: May play a role in the initiation and completion of mitosis.
messages: Nucleus

284813:ECU02 0810
gene id: 284813:ECU02_0810
uniprot id: Q8SSF6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

284813:ECU08 1280
gene id: 284813:ECU08_1280
uniprot id: Q8SUN2
names: Developmental Stage
messages: Expressed in late sporogonial stages.

284813:ECU01 0700
gene id: 284813:ECU01_0700
uniprot id: O96719
names: Function
names: Similarity
names: Subunit
messages: As a subunit of eukaryotic initiation factor 2 (eIF-2), involved in the early steps of protein synthesis. In the presence of GTP, eIF-2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex and initiation factors eIF-1, eIF-1A and eIF-3 to form the 43S pre-initiation complex (43S PIC), a step that determines the rate of protein translation. The 43S PIC binds to mRNA and scans downstream to the initiation codon, where it forms a 48S initiation complex by codon-anticodon base pairing. This leads to the displacement of eIF-1 to allow GTPase-activating protein (GAP) eIF-5-mediated hydrolysis of eIF2-bound GTP. Hydrolysis of GTP and release of Pi, which makes GTP hydrolysis irreversible, causes the release of the eIF-2-GDP binary complex from the 40S subunit, an event that is essential for the subsequent joining of the 60S ribosomal subunit to form an elongation-competent 80S ribosome. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must be exchanged with GTP by way of a reaction catalyzed by GDP-GTP exchange factor (GEF) eIF-2B.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Eukaryotic translation initiation factor 2 (eIF-2) is a heterotrimeric G-protein composed of an alpha, a beta and a gamma subunit. The factors eIF-1, eIF-2, eIF-3, TIF5/eIF-5 and methionyl-tRNAi form a multifactor complex (MFC) that may bind to the 40S ribosome.

284813:ECU04 1580
gene id: 284813:ECU04_1580
uniprot id: Q8SVQ1
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU07 1660
gene id: 284813:ECU07_1660
uniprot id: Q8SRG9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

284813:ECU05 1140
gene id: 284813:ECU05_1140
uniprot id: Q8SRV6
names: Similarity
messages: Belongs to the AAA ATPase family.

284813:ECU11 1770
gene id: 284813:ECU11_1770
uniprot id: Q8SQS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters in mitosomes.
messages: Mitosome

284813:ECU08 0550
gene id: 284813:ECU08_0550
uniprot id: Q8SRD8
names: Developmental Stage
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Expressed in late sporogonial stages.
messages: Monomer.

284813:ECU09 0690
gene id: 284813:ECU09_0690
uniprot id: Q8STT8
names: Similarity
messages: Belongs to the DeSI family.

284813:ECU08 2060
gene id: 284813:ECU08_2060
uniprot id: Q8SUI0
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU04 0350
gene id: 284813:ECU04_0350
uniprot id: Q8SS63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.
messages: Homodimer.

284813:ECU05 1320
gene id: 284813:ECU05_1320
uniprot id: Q8SRU8
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

284813:ECU07 0040
gene id: 284813:ECU07_0040
uniprot id: P0CS98
uniprot id: P0CS99
names: Developmental Stage
names: Similarity
messages: Belongs to the UPF0328 family.
messages: Expressed in late sporogonial stages.

284813:ECU06 0530
gene id: 284813:ECU06_0530
uniprot id: Q8SVD1
names: Similarity
messages: Belongs to the TUB family.

284813:ECU04 0170
gene id: 284813:ECU04_0170
uniprot id: Q8SVY0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane
messages: May function both as a monomer and a homodimer.

284813:ECU06 1460
gene id: 284813:ECU06_1460
uniprot id: Q8SRN0
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

284813:ECU11 0890
gene id: 284813:ECU11_0890
uniprot id: Q8SQW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

284813:ECU06 1380
gene id: 284813:ECU06_1380
uniprot id: Q8SRN5
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

284813:ECU04 1160
gene id: 284813:ECU04_1160
uniprot id: Q8SS26
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

284813:ECU07 1010
gene id: 284813:ECU07_1010
uniprot id: Q8SRJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

284813:ECU08 1040
gene id: 284813:ECU08_1040
uniprot id: Q8STD9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

284813:ECU09 1950
gene id: 284813:ECU09_1950
uniprot id: Q8STK5
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Expressed in late sporogonial stages.
messages: Membrane

284813:ECU03 0170
gene id: 284813:ECU03_0170
uniprot id: Q8SW72
names: Subcellular Location Annotation
messages: Membrane

284813:ECU10 0220
gene id: 284813:ECU10_0220
uniprot id: Q8SR77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

284813:ECU05 0310
gene id: 284813:ECU05_0310
uniprot id: Q8SRZ9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

284813:ECU03 1070
gene id: 284813:ECU03_1070
uniprot id: Q8SW23
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIA subunit 1 family.
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.
messages: TFIIA is a heterodimer of the large subunit and the small subunit gamma.

284813:ECU08 1780
gene id: 284813:ECU08_1780
uniprot id: Q8SR91
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

284813:ECU08 0410
gene id: 284813:ECU08_0410
uniprot id: Q8SRE2
names: Caution
names: Developmental Stage
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Expressed in late sporogonial stages.
messages: Monoubiquitinated to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for H3K4me and H3K79me formation (By similarity).
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H2BK123ub1 = monoubiquitinated Lys-122.

284813:ECU11 0870
gene id: 284813:ECU11_0870
uniprot id: Q8SQW6
names: Developmental Stage
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Expressed in late sporogonial stages.

284813:ECU09 1640
gene id: 284813:ECU09_1640
uniprot id: Q8SQK9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity).
messages: Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
messages: P-body
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284813:ECU10 0320
gene id: 284813:ECU10_0320
uniprot id: Q8SUH1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

284813:ECU07 0610i
gene id: 284813:ECU07_0610i
uniprot id: Q8SRK6
names: Cofactor
names: Developmental Stage
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Expressed in late sporogonial stages.
messages: Homodimer. Forms a complex with MRE11.
messages: Involved in DNA double-strand break repair (DSBR). The RAD50/MRE11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific exonuclease activity. RAD50 provides ATP-dependent control of MRE11 by unwinding and/or repositioning DNA ends into the MRE11 active site (By similarity).
messages: The zinc-hook, which separates the large intramolecular coiled coil regions, contains 2 Cys residues that coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another RAD50 molecule, thereby forming a V-shaped homodimer.

284813:ECU10 1200i
gene id: 284813:ECU10_1200i
uniprot id: Q8SR24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

284813:ECU02 1200
gene id: 284813:ECU02_1200
uniprot id: Q8SWA6
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU08 0770
gene id: 284813:ECU08_0770
uniprot id: Q8SRC4
names: Similarity
messages: Belongs to the type-1 OGG1 family.

284813:ECU03 0270
gene id: 284813:ECU03_0270
uniprot id: Q8SSC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

284813:ECU10 0260
gene id: 284813:ECU10_0260
uniprot id: Q8SR74
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.

284813:ECU02 1300
gene id: 284813:ECU02_1300
uniprot id: Q8SSD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

284813:ECU11 1980
gene id: 284813:ECU11_1980
uniprot id: Q8SQR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
messages: Involved in DNA repair. May regulate the activity of protein(s) involved in double strand break repair caused by gamma rays (By similarity).
messages: Nucleus

284813:ECU11 1760
gene id: 284813:ECU11_1760
uniprot id: Q8SQS3
names: Similarity
messages: Belongs to the importin alpha family.

284813:ECU11 0470
gene id: 284813:ECU11_0470
uniprot id: Q8SQY6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

284813:ECU04 0630
gene id: 284813:ECU04_0630
uniprot id: Q8SS54
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284813:ECU09 0740
gene id: 284813:ECU09_0740
uniprot id: Q8STT4
names: Subcellular Location Annotation
messages: Membrane

284813:ECU02 0200
gene id: 284813:ECU02_0200
uniprot id: Q8SWG3
names: Similarity
messages: Belongs to the lipin family.

284813:ECU05 1020
gene id: 284813:ECU05_1020
uniprot id: Q8SRW0
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

284813:ECU03 1220
gene id: 284813:ECU03_1220
uniprot id: Q8SQI3
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU10 0300
gene id: 284813:ECU10_0300
uniprot id: Q8SR71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Sterol O-acyltransferase that catalyzes the formation of stery esters.

284813:ECU10 1040
gene id: 284813:ECU10_1040
uniprot id: Q8SR34
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Expressed in late sporogonial stages.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity).
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1).
messages: Vacuole membrane

284813:ECU05 1310
gene id: 284813:ECU05_1310
uniprot id: Q8SRU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.
messages: Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.
messages: Cytoplasm
messages: P-body

284813:ECU05 0250
gene id: 284813:ECU05_0250
uniprot id: Q8SS05
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).
messages: Cytoplasm

284813:ECU01 0960
gene id: 284813:ECU01_0960
uniprot id: Q8SSK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

284813:ECU09 1240
gene id: 284813:ECU09_1240
uniprot id: Q8STQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm

284813:ECU03 0950
gene id: 284813:ECU03_0950
uniprot id: Q8SS93
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

284813:ECU01 0190
gene id: 284813:ECU01_0190
uniprot id: O62585
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Cytoplasm
messages: Homotetramer.
messages: Interconversion of serine and glycine.

284813:ECU11 1050
gene id: 284813:ECU11_1050
uniprot id: Q8SQV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

284813:ECU11 1540
gene id: 284813:ECU11_1540
uniprot id: Q8SU17
names: Similarity
messages: Belongs to the hexokinase family.

284813:ECU06 0840
gene id: 284813:ECU06_0840
uniprot id: Q8SRQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SSU72 phosphatase family.
messages: Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. SSU72 is required for 3'-end formation of snoRNAs.
messages: Component of the cleavage and polyadenylation factor (CPF) complex.
messages: Nucleus
messages: Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1).

284813:ECU10 1310i
gene id: 284813:ECU10_1310i
uniprot id: Q8SR17
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284813:ECU08 0060
gene id: 284813:ECU08_0060
uniprot id: Q8ST53
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU08 1520
gene id: 284813:ECU08_1520
uniprot id: Q8SR97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

284813:ECU04 0100
gene id: 284813:ECU04_0100
uniprot id: Q8SVY6
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU09 1440
gene id: 284813:ECU09_1440
uniprot id: Q8SQL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

284813:ECU11 0810
gene id: 284813:ECU11_0810
uniprot id: Q8SU51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

284813:ECU04 0950
gene id: 284813:ECU04_0950
uniprot id: Q8SS37
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU05 0920
gene id: 284813:ECU05_0920
uniprot id: Q8SRW6
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: Component of the small ribosomal subunit.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

284813:ECU10 0630
gene id: 284813:ECU10_0630
uniprot id: Q8SR53
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Component of the T-complex protein 1 (TCP1) complex.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.

284813:ECU11 1230
gene id: 284813:ECU11_1230
uniprot id: Q8SU30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

284813:ECU06 1060
gene id: 284813:ECU06_1060
uniprot id: Q8SV98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC24 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284813:ECU02 1360
gene id: 284813:ECU02_1360
uniprot id: Q8SSD7
names: Developmental Stage
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Expressed in late sporogonial stages.

284813:ECU03 0980
gene id: 284813:ECU03_0980
uniprot id: Q8SW31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Serine/threonine protein kinase involved in regulation of exocytosis.

284813:ECU09 2030
gene id: 284813:ECU09_2030
uniprot id: P0CS99
names: Developmental Stage
names: Similarity
messages: Belongs to the UPF0328 family.
messages: Expressed in late sporogonial stages.

284813:ECU07 0460
gene id: 284813:ECU07_0460
uniprot id: Q8SRL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

284813:ECU10 1750
gene id: 284813:ECU10_1750
uniprot id: Q8SU99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

284813:ECU04 0750
gene id: 284813:ECU04_0750
uniprot id: Q8SS48
names: Developmental Stage
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Expressed in late sporogonial stages.
messages: Homodimer. The tRNA molecule probably binds across the dimer (By similarity).

284813:ECU10 1360
gene id: 284813:ECU10_1360
uniprot id: Q8SUC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

284813:ECU01 0480
gene id: 284813:ECU01_0480
uniprot id: Q8SWN7
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

284813:ECU11 1740
gene id: 284813:ECU11_1740
uniprot id: Q8SU06
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

284813:ECU11 1470
gene id: 284813:ECU11_1470
uniprot id: Q8SQT6
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU10 0600
gene id: 284813:ECU10_0600
uniprot id: Q8SR55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: Nucleus

284813:ECU07 0930
gene id: 284813:ECU07_0930
uniprot id: Q8SUZ9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

284813:ECU01 0440
gene id: 284813:ECU01_0440
uniprot id: Q8SWP0
names: Developmental Stage
messages: Expressed in late sporogonial stages.

284813:ECU07 1740
gene id: 284813:ECU07_1740
uniprot id: Q8SUU7
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU10 0760
gene id: 284813:ECU10_0760
uniprot id: Q8SR44
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU03 0650
gene id: 284813:ECU03_0650
uniprot id: Q8SSA6
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Component of the small ribosomal subunit.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU01 1540
gene id: 284813:ECU01_1540
uniprot id: Q8ST97
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU08 0470
gene id: 284813:ECU08_0470
uniprot id: Q8SRE1
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: PPIases accelerate the folding of proteins. They catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

284813:ECU07 0060
gene id: 284813:ECU07_0060
uniprot id: Q8SV55
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU10 0720
gene id: 284813:ECU10_0720
uniprot id: Q8SR46
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

284813:ECU04 1180
gene id: 284813:ECU04_1180
uniprot id: Q8SS24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

284813:ECU03 0930
gene id: 284813:ECU03_0930
uniprot id: Q8SS94
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

284813:ECU11 1180
gene id: 284813:ECU11_1180
uniprot id: Q8SQV3
names: Similarity
messages: Belongs to the phospholipase D family.

284813:ECU06 1100i
gene id: 284813:ECU06_1100i
uniprot id: Q8SRP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with TFIID-IIA (DA complex) to form TFIID-IIA-IIB (DAB-complex) which is then recognized by polymerase II.
messages: Belongs to the TFIIB family.
messages: General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.
messages: Nucleus

284813:ECU06 1110
gene id: 284813:ECU06_1110
uniprot id: Q8SRP2
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.

284813:ECU04 0460
gene id: 284813:ECU04_0460
uniprot id: Q8SS59
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

284813:ECU01 0240
gene id: 284813:ECU01_0240
uniprot id: Q8SSM8
names: Developmental Stage
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.
messages: Expressed in late sporogonial stages.

284813:ECU05 0900
gene id: 284813:ECU05_0900
uniprot id: Q8SRW8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

284813:ECU11 0540
gene id: 284813:ECU11_0540
uniprot id: O96772
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: May act as a chaperone.
messages: Nucleus

284813:ECU02 1540
gene id: 284813:ECU02_1540
uniprot id: Q8SW86
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU10 0560
gene id: 284813:ECU10_0560
uniprot id: Q8SR58
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284813:ECU11 0510
gene id: 284813:ECU11_0510
uniprot id: Q8SU65
names: Caution
names: Developmental Stage
messages: Although it contains a polysaccharide deacetylase domain, the protein does not display any chitin deacetylase activity.
messages: Expressed in late sporogonial stages.

284813:ECU01 1510
gene id: 284813:ECU01_1510
uniprot id: Q8ST94
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU09 0140
gene id: 284813:ECU09_0140
uniprot id: Q8SQQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Cytoplasm
messages: Nucleus

284813:ECU02 0240
gene id: 284813:ECU02_0240
uniprot id: Q8SSI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

284813:ECU07 1260
gene id: 284813:ECU07_1260
uniprot id: Q8SRI4
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

284813:ECU01 0310
gene id: 284813:ECU01_0310
uniprot id: Q8SSM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Cytoplasm

284813:ECU04 0330
gene id: 284813:ECU04_0330
uniprot id: Q8SS64
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL27 family.

284813:ECU03 0200
gene id: 284813:ECU03_0200
uniprot id: Q8SW70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Nucleus
messages: Putative deoxyribonuclease.

284813:ECU07 0130
gene id: 284813:ECU07_0130
uniprot id: Q8SRM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ASF1 family.
messages: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
messages: Interacts with histone H3 and histone H4.
messages: Nucleus

284813:ECU04 0510
gene id: 284813:ECU04_0510
uniprot id: Q8SVW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRR1 family.
messages: nucleolus

284813:ECU08 1910
gene id: 284813:ECU08_1910
uniprot id: Q8SR87
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

284813:ECU05 0290
gene id: 284813:ECU05_0290
uniprot id: Q8SS01
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Non-catalytic component of the proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity (By similarity).
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel (By similarity).

284813:ECU10 1350
gene id: 284813:ECU10_1350
uniprot id: Q8SUC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
messages: Nucleus

284813:ECU03 0420
gene id: 284813:ECU03_0420
uniprot id: Q8SW60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

284813:ECU04 1070
gene id: 284813:ECU04_1070
uniprot id: Q8SS31
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

284813:ECU05 0400
gene id: 284813:ECU05_0400
uniprot id: Q8SRZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus

284813:ECU04 1670
gene id: 284813:ECU04_1670
uniprot id: Q8SVP2
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU08 0670
gene id: 284813:ECU08_0670
uniprot id: Q8SRD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly (By similarity).
messages: spindle pole body

284813:ECU10 0440
gene id: 284813:ECU10_0440
uniprot id: Q8SR63
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent rRNA helicase required for pre-ribosomal RNA processing. Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
messages: Interacts with the SSU processome.
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284813:ECU06 1610
gene id: 284813:ECU06_1610
uniprot id: Q8SV64
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU11 0240
gene id: 284813:ECU11_0240
uniprot id: Q8SU86
names: Similarity
messages: Belongs to the exportin family.

284813:ECU02 1390
gene id: 284813:ECU02_1390
uniprot id: Q8SW97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

284813:ECU04 1380
gene id: 284813:ECU04_1380
uniprot id: Q8SS16
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

284813:ECU06 0720
gene id: 284813:ECU06_0720
uniprot id: Q8SVB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).

284813:ECU05 0110
gene id: 284813:ECU05_0110
uniprot id: Q8SVN5
names: Developmental Stage
messages: Expressed in late sporogonial stages.

284813:ECU03 0080
gene id: 284813:ECU03_0080
uniprot id: Q8SW79
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU03 1410
gene id: 284813:ECU03_1410
uniprot id: Q8SS79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

284813:ECU05 1030
gene id: 284813:ECU05_1030
uniprot id: Q8SRV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

284813:ECU02 0150
gene id: 284813:ECU02_0150
uniprot id: Q8SWG8
names: Developmental Stage
names: Subcellular Location Annotation
messages: Expressed in late sporogonial stages.
messages: Spore wall

284813:ECU09 1650
gene id: 284813:ECU09_1650
uniprot id: Q8STM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

284813:ECU07 0790
gene id: 284813:ECU07_0790
uniprot id: Q8SV08
names: Similarity
messages: Belongs to the SEC3 family.

284813:ECU04 1290
gene id: 284813:ECU04_1290
uniprot id: Q8SS19
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

284813:ECU10 0670
gene id: 284813:ECU10_0670
uniprot id: Q8SUF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

284813:ECU10 1600
gene id: 284813:ECU10_1600
uniprot id: Q8SUA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MND1 family.
messages: Nucleus
messages: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.

284813:ECU02 0090
gene id: 284813:ECU02_0090
uniprot id: Q8SWH3
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU04 1000
gene id: 284813:ECU04_1000
uniprot id: Q8SS35
names: Developmental Stage
names: Function
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping.
messages: Expressed in late sporogonial stages.

284813:ECU04 1560
gene id: 284813:ECU04_1560
uniprot id: Q8SS11
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small GTPase superfamily. Ran family.
messages: Expressed in late sporogonial stages.
messages: Found in a nuclear export complex with RanGTP, exportin and pre-miRNA (By similarity).
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export (By similarity).
messages: Nucleus

284813:ECU08 0260
gene id: 284813:ECU08_0260
uniprot id: Q8SRF2
names: Similarity
messages: Belongs to the cyclin family.

284813:ECU09 1870
gene id: 284813:ECU09_1870
uniprot id: Q8SQJ8
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPP synthase family.
messages: Cis-prenyl transferase that adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP).
messages: Endoplasmic reticulum membrane
messages: Expressed in late sporogonial stages.

284813:ECU09 2010
gene id: 284813:ECU09_2010
uniprot id: Q8STK1
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU10 0820
gene id: 284813:ECU10_0820
uniprot id: Q8SR42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles.
messages: S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (By similarity).
messages: nucleolus

284813:ECU03 0230
gene id: 284813:ECU03_0230
uniprot id: Q8SSC8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

284813:ECU05 1460
gene id: 284813:ECU05_1460
uniprot id: Q8SVG5
names: Subcellular Location Annotation
messages: Membrane

284813:ECU04 0700
gene id: 284813:ECU04_0700
uniprot id: Q8SS50
names: Similarity
messages: Belongs to the PPP phosphatase family.

284813:ECU01 1230
gene id: 284813:ECU01_1230
uniprot id: Q8SSJ5
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Component of the ribosome quality control complex (RQC), composed of the E3 ubiquitin ligase LTN1, RQC1 and RQC2, as well as CDC48 and its ubiquitin-binding cofactors. RQC forms a stable complex with 60S ribosomal subunits.
messages: Endoplasmic reticulum
messages: Expressed in late sporogonial stages.
messages: Involved in spindle disassembly, degradation of ubiquitinated proteins and protein export from the endoplasmic reticulum to the cytoplasm. Acts as a chaperone that collects ubiquitinated substrates. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. CDC48 may provide the mechanical force that dislodges the polyubiquitinated nascent peptides from the exit channel.

284813:ECU05 1400
gene id: 284813:ECU05_1400
uniprot id: Q8SRU3
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel (By similarity).
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity (By similarity).

284813:ECU09 0440
gene id: 284813:ECU09_0440
uniprot id: Q8SQP4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Glutarylation at Lys-94 (H4K91glu) destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

284813:ECU11 1750
gene id: 284813:ECU11_1750
uniprot id: Q8SQS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat TAF5 family.
messages: Component of the TFIID and SAGA complexes. TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs) (By similarity).
messages: Nucleus
messages: TAFs are components of the transcription factor IID (TFIID) complex that are essential for mediating regulation of RNA polymerase transcription. Regulates the genes involved in ubiquitin-dependent proteolysis during the progression of M-phase of mitosis (By similarity).

284813:ECU09 0230
gene id: 284813:ECU09_0230
uniprot id: Q8STX3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

284813:ECU03 1370
gene id: 284813:ECU03_1370
uniprot id: Q8SS80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

284813:ECU05 0300
gene id: 284813:ECU05_0300
uniprot id: Q8SS00
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

284813:ECU07 1780
gene id: 284813:ECU07_1780
uniprot id: Q8SUU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

284813:ECU11 1330
gene id: 284813:ECU11_1330
uniprot id: Q8SQU6
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU05 1280
gene id: 284813:ECU05_1280
uniprot id: Q8SRV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Forms a complex with RAD50.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing (By similarity).
messages: Nucleus

284813:ECU11 1270
gene id: 284813:ECU11_1270
uniprot id: Q8SU27
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Component of the SWR1 chromatin remodeling complex, the INO80 chromatin remodeling complex, and of the R2TP complex.
messages: DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
messages: Expressed in late sporogonial stages.
messages: Nucleus

284813:ECU02 0340
gene id: 284813:ECU02_0340
uniprot id: Q8SSI0
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU02 0520
gene id: 284813:ECU02_0520
uniprot id: Q8SSH3
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Component of the T-complex protein 1 (TCP1) complex.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.

284813:ECU08 1160i
gene id: 284813:ECU08_1160i
uniprot id: Q8SRA7
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

284813:ECU08 1100
gene id: 284813:ECU08_1100
uniprot id: Q8SRB1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

284813:ECU10 0130
gene id: 284813:ECU10_0130
uniprot id: Q8SQI9
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a regulatory subunit of the 26S proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH (By similarity).
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel (By similarity).

284813:ECU09 1260
gene id: 284813:ECU09_1260
uniprot id: Q8STQ0
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

284813:ECU03 0040
gene id: 284813:ECU03_0040
uniprot id: Q8SW83
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU01 1210
gene id: 284813:ECU01_1210
uniprot id: Q8SSJ7
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

284813:ECU11 0130
gene id: 284813:ECU11_0130
uniprot id: Q8STJ2
names: Similarity
messages: To E.cuniculi ECU03_0120.

284813:ECU04 1090
gene id: 284813:ECU04_1090
uniprot id: Q8SS30
names: Similarity
messages: Belongs to the actin family.

284813:ECU11 0560
gene id: 284813:ECU11_0560
uniprot id: Q8SU63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

284813:ECU08 0300
gene id: 284813:ECU08_0300
uniprot id: Q8SUT3
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

284813:ECU09 0130
gene id: 284813:ECU09_0130
uniprot id: Q8SQQ4
names: Similarity
messages: Belongs to the SecY/SEC61-alpha family.

284813:ECU02 0980
gene id: 284813:ECU02_0980
uniprot id: Q8SWC1
names: Similarity
messages: Belongs to the archease family.

284813:ECU01 0070
gene id: 284813:ECU01_0070
uniprot id: Q8ST97
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU06 0870
gene id: 284813:ECU06_0870
uniprot id: Q8SRQ5
names: Subcellular Location Annotation
messages: Membrane

284813:ECU08 0680
gene id: 284813:ECU08_0680
uniprot id: Q8SRD1
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity). The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex (By similarity).

284813:ECU05 1690
gene id: 284813:ECU05_1690
uniprot id: Q8ST65
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU02 1560
gene id: 284813:ECU02_1560
uniprot id: Q8STE0
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU08 0880
gene id: 284813:ECU08_0880
uniprot id: Q8SRB8
names: Cofactor
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Binds 1 [4Fe-4S] cluster. The cluster does not appear to play a role in catalysis, but is probably involved in the proper positioning of the enzyme along the DNA strand.
messages: Expressed in late sporogonial stages.
messages: Mitochondrion
messages: Nucleus

284813:ECU08 0970
gene id: 284813:ECU08_0970
uniprot id: Q8SRB4
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU10 0990
gene id: 284813:ECU10_0990
uniprot id: O62581
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

284813:ECU11 0140
gene id: 284813:ECU11_0140
uniprot id: Q8SQI1
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA glycosylase MPG family.
messages: Expressed in late sporogonial stages.
messages: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
messages: Nucleus

284813:ECU03 0580
gene id: 284813:ECU03_0580
uniprot id: Q8SSA9
names: Similarity
messages: Belongs to the peptidase C19 family.

284813:ECU04 0620
gene id: 284813:ECU04_0620
uniprot id: Q8SVV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

284813:ECU06 1480
gene id: 284813:ECU06_1480
uniprot id: Q8SRM9
names: Subcellular Location Annotation
messages: Membrane

284813:ECU11 1510
gene id: 284813:ECU11_1510
uniprot id: Q8SQT3
names: Subcellular Location Annotation
messages: Membrane

284813:ECU01 1060
gene id: 284813:ECU01_1060
uniprot id: Q8SSK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATPase activity of XPB/SSL2, but not its helicase activity, is required for DNA opening. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. The ATP-dependent helicase activity of XPB/SSL2 is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Belongs to the helicase family. RAD25/XPB subfamily.
messages: Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.
messages: Nucleus

284813:ECU11 2090
gene id: 284813:ECU11_2090
uniprot id: Q8STZ1
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU11 0900
gene id: 284813:ECU11_0900
uniprot id: Q8SU49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

284813:ECU04 0450
gene id: 284813:ECU04_0450
uniprot id: Q8SS60
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with RPS21.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.

284813:ECU11 1880
gene id: 284813:ECU11_1880
uniprot id: Q8SQR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

284813:ECU05 0070
gene id: 284813:ECU05_0070
uniprot id: Q8SVN8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Inhibited by organophosphorus esters.
messages: Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity).

284813:ECU04 0140
gene id: 284813:ECU04_0140
uniprot id: Q8SS72
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: Component of the small ribosomal subunit.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU07 0590
gene id: 284813:ECU07_0590
uniprot id: Q8SV20
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

284813:ECU10 1180
gene id: 284813:ECU10_1180
uniprot id: Q8SR25
names: Similarity
messages: Belongs to the UFD1 family.

284813:ECU02 0070
gene id: 284813:ECU02_0070
uniprot id: Q8SWH5
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU10 1330
gene id: 284813:ECU10_1330
uniprot id: Q8SR16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

284813:ECU02 0610
gene id: 284813:ECU02_0610
uniprot id: Q8SSG9
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Component of the large ribosomal subunit.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Nucleus

284813:ECU08 1830
gene id: 284813:ECU08_1830
uniprot id: Q8SUJ4
names: Similarity
messages: Belongs to the TBCC family.

284813:ECU05 0670
gene id: 284813:ECU05_0670
uniprot id: Q8SRY0
names: PTM
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.
messages: Phosphorylated.

284813:ECU10 0240
gene id: 284813:ECU10_0240
uniprot id: Q8SR76
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Component of the T-complex protein 1 (TCP1) complex.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.

284813:ECU02 1450
gene id: 284813:ECU02_1450
uniprot id: Q8SW92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
messages: Component of the TFIIH holo complex.
messages: Nucleus
messages: Protein kinase component of transcription factor IIH (TFIIH) which phosphorylates the C-terminal domain of RNA polymerase II during transition from transcription to elongation after preinitiation complex (PIC) formation, thereby positively regulating transcription. Essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA (By similarity).

284813:ECU08 1110
gene id: 284813:ECU08_1110
uniprot id: Q8SRB0
names: Developmental Stage
names: Similarity
messages: Belongs to the WD repeat G protein beta family.
messages: Expressed in late sporogonial stages.

284813:ECU08 0890
gene id: 284813:ECU08_0890
uniprot id: Q8SRB7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

284813:ECU08 0440
gene id: 284813:ECU08_0440
uniprot id: Q8SUS7
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU09 1805
gene id: 284813:ECU09_1805
uniprot id: Q8SQK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner. LSM2 binds specifically to the 3'-terminal U-tract of U6 snRNA. Required for processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity).
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

284813:ECU06 1280
gene id: 284813:ECU06_1280
uniprot id: Q8SV85
names: Similarity
messages: Belongs to the SNAP family.

284813:ECU06 1650
gene id: 284813:ECU06_1650
uniprot id: Q8SV60
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU02 0770
gene id: 284813:ECU02_0770
uniprot id: Q8SSF9
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS17 family.
messages: Component of the small ribosomal subunit.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU07 1130
gene id: 284813:ECU07_1130
uniprot id: Q8SRI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

284813:ECU06 1570
gene id: 284813:ECU06_1570
uniprot id: Q8SRM5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

284813:ECU04 0125i
gene id: 284813:ECU04_0125i
uniprot id: Q8SS73
names: Cofactor
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 1 zinc ion per subunit.

284813:ECU09 1840
gene id: 284813:ECU09_1840
uniprot id: Q8SQK0
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a regulatory subunit of the 26S proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH (By similarity).
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel (By similarity).

284813:ECU07 0770
gene id: 284813:ECU07_0770
uniprot id: Q8SRJ9
names: Subcellular Location Annotation
messages: Nucleus membrane
messages: perinuclear region

284813:ECU04 0930
gene id: 284813:ECU04_0930
uniprot id: Q8SS38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Nucleus

284813:ECU10 1790
gene id: 284813:ECU10_1790
uniprot id: Q8SQZ6
names: Developmental Stage
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP). Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. Thereby, may play a special role in Ap4A homeostasis.
messages: Expressed in late sporogonial stages.
messages: Homodimer.

284813:ECU06 1420i
gene id: 284813:ECU06_1420i
uniprot id: Q8SRN4
names: Subcellular Location Annotation
messages: Membrane

284813:ECU09 0850
gene id: 284813:ECU09_0850
uniprot id: Q8STS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

284813:ECU06 0350
gene id: 284813:ECU06_0350
uniprot id: Q8SRS3
names: Function
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

284813:ECU06 0990
gene id: 284813:ECU06_0990
uniprot id: Q8SRP9
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Component of the T-complex protein 1 (TCP1) complex.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.

284813:ECU02 0900
gene id: 284813:ECU02_0900
uniprot id: Q8SSF3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

284813:ECU04 0910
gene id: 284813:ECU04_0910
uniprot id: Q8SS39
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

284813:ECU07 0600
gene id: 284813:ECU07_0600
uniprot id: Q8SV19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adrenodoxin/putidaredoxin family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
messages: Mitosome

284813:ECU11 1670
gene id: 284813:ECU11_1670
uniprot id: Q8SQS5
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel (By similarity).
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity (By similarity).

284813:ECU03 1180
gene id: 284813:ECU03_1180
uniprot id: Q8SS86
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Expression is low in meronts, but becomes induced in sporonts and spores.
messages: May be involved in the degradation of proteins for nutrient acquisition or possess a regulatory function by proteolytic activation of proproteins.
messages: Membrane

284813:ECU08 1440
gene id: 284813:ECU08_1440
uniprot id: Q8SUM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

284813:ECU07 1730
gene id: 284813:ECU07_1730
uniprot id: Q8SUU8
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU02 0490
gene id: 284813:ECU02_0490
uniprot id: Q8SWE5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with TAH18. Interacts with MIA40.
messages: The C-terminal domain binds 1 Fe-S cluster but is otherwise mostly in an intrinsically disordered conformation.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

284813:ECU06 1450
gene id: 284813:ECU06_1450
uniprot id: Q8SRN1
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

284813:ECU08 0080
gene id: 284813:ECU08_0080
uniprot id: O62583
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).

284813:ECU03 1010
gene id: 284813:ECU03_1010
uniprot id: Q8SW28
names: Developmental Stage
names: Similarity
messages: Belongs to the 14-3-3 family.
messages: Expressed in late sporogonial stages.

284813:ECU02 0750i
gene id: 284813:ECU02_0750i
uniprot id: Q8SSG1
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the large ribosomal subunit.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU06 1500
gene id: 284813:ECU06_1500
uniprot id: Q8SV70
names: Subcellular Location Annotation
messages: Membrane

284813:ECU08 0650
gene id: 284813:ECU08_0650
uniprot id: Q8SRD3
names: Similarity
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.

284813:ECU04 1210
gene id: 284813:ECU04_1210
uniprot id: Q8SS23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

284813:ECU06 0200
gene id: 284813:ECU06_0200
uniprot id: Q8SRT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

284813:ECU01 1120
gene id: 284813:ECU01_1120
uniprot id: Q8SWJ2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

284813:ECU05 0870
gene id: 284813:ECU05_0870
uniprot id: Q8SRX0
names: Similarity
messages: Belongs to the HAM1 NTPase family.

284813:ECU07 1050
gene id: 284813:ECU07_1050
uniprot id: Q8SUZ0
names: Similarity
messages: Belongs to the NAD kinase family.

284813:ECU01 0250
gene id: 284813:ECU01_0250
uniprot id: Q8SWQ4
names: Developmental Stage
messages: Expressed in late sporogonial stages.

284813:ECU11 0010
gene id: 284813:ECU11_0010
uniprot id: Q8STE8
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU02 0800
gene id: 284813:ECU02_0800
uniprot id: Q8SSF7
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

284813:ECU09 0960
gene id: 284813:ECU09_0960
uniprot id: Q8STR9
names: Similarity
messages: Belongs to the SPCS3 family.

284813:ECU06 0280
gene id: 284813:ECU06_0280
uniprot id: Q8SRS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

284813:ECU07 1420
gene id: 284813:ECU07_1420
uniprot id: Q8SRH6
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Non-catalytic component of the proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity (By similarity).
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel (By similarity).

284813:ECU04 0640
gene id: 284813:ECU04_0640
uniprot id: Q8SS53
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

284813:ECU11 1920
gene id: 284813:ECU11_1920
uniprot id: Q8SQR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

284813:ECU01 0910
gene id: 284813:ECU01_0910
uniprot id: Q8SWK6
names: Developmental Stage
names: Subcellular Location Annotation
messages: Expressed in late sporogonial stages.
messages: Membrane

284813:ECU03 0910
gene id: 284813:ECU03_0910
uniprot id: Q8SS96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
messages: Involved in DNA repair. May regulate the activity of protein(s) involved in double strand break repair caused by gamma rays (By similarity).
messages: Nucleus

284813:ECU08 1660
gene id: 284813:ECU08_1660
uniprot id: Q8SR92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Nucleus
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.
messages: centromere

284813:ECU04 0790
gene id: 284813:ECU04_0790
uniprot id: Q8SS46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

284813:ECU01 1290
gene id: 284813:ECU01_1290
uniprot id: Q8SSJ2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

284813:ECU03 0440
gene id: 284813:ECU03_0440
uniprot id: Q8SSB7
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

284813:ECU03 0120
gene id: 284813:ECU03_0120
uniprot id: Q8SW75
names: Similarity
messages: To E.cuniculi ECU05_1600/ECU11_0130.

284813:ECU10 1460
gene id: 284813:ECU10_1460
uniprot id: Q8SR10
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284813:ECU08 0330
gene id: 284813:ECU08_0330
uniprot id: Q8SUT1
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MMR1/HSR1 GTP-binding protein family.
messages: Expressed in late sporogonial stages.
messages: Required for normal processing of ribosomal pre-rRNA. Required for cell proliferation. Binds GTP (By similarity).
messages: nucleolus

284813:ECU08 1930
gene id: 284813:ECU08_1930
uniprot id: Q8SQH8
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Expressed in late sporogonial stages.
messages: GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

284813:ECU03 0030
gene id: 284813:ECU03_0030
uniprot id: Q8STE8
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU04 1130
gene id: 284813:ECU04_1130
uniprot id: Q8SS28
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

284813:ECU01 0955
gene id: 284813:ECU01_0955
uniprot id: Q8SWK3
names: Similarity
messages: Belongs to the MBF1 family.

284813:ECU11 0980
gene id: 284813:ECU11_0980
uniprot id: Q8SQW1
names: Similarity
messages: Belongs to the synaptobrevin family.

284813:ECU04 1360
gene id: 284813:ECU04_1360
uniprot id: Q8SVR6
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

284813:ECU10 0530
gene id: 284813:ECU10_0530
uniprot id: Q8SR60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

284813:ECU04 1400
gene id: 284813:ECU04_1400
uniprot id: Q8SS15
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

284813:ECU11 0030
gene id: 284813:ECU11_0030
uniprot id: Q8SU90
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU11 0020
gene id: 284813:ECU11_0020
uniprot id: Q8STJ4
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU10 0870
gene id: 284813:ECU10_0870
uniprot id: Q8SR40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

284813:ECU01 1430
gene id: 284813:ECU01_1430
uniprot id: O62584
names: Similarity
messages: Belongs to the thymidylate synthase family.

284813:ECU02 0760
gene id: 284813:ECU02_0760
uniprot id: Q8SSG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids.
messages: Component of the signal peptidase complex (SPC) composed of a catalytic subunit SEC11 and three accessory subunits SPC1, SPC2 and SPC3 (By similarity). The complex induces a local thinning of the ER membrane which is used to measure the length of the signal peptide (SP) h-region of protein substrates. This ensures the selectivity of the complex towards h-regions shorter than 18-20 amino acids (By similarity). SPC associates with the translocon complex.
messages: Endoplasmic reticulum membrane

284813:ECU03 1170
gene id: 284813:ECU03_1170
uniprot id: Q8SW18
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU04 0580
gene id: 284813:ECU04_0580
uniprot id: Q8SS56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

284813:ECU07 0070
gene id: 284813:ECU07_0070
uniprot id: Q8SV54
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU09 1820
gene id: 284813:ECU09_1820
uniprot id: Q8STL3
names: Developmental Stage
messages: Expressed in late sporogonial stages.

284813:ECU05 0470
gene id: 284813:ECU05_0470
uniprot id: Q8SVL8
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

284813:ECU07 0700
gene id: 284813:ECU07_0700
uniprot id: Q8SRK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284813:ECU05 1230
gene id: 284813:ECU05_1230
uniprot id: Q8SRV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

284813:ECU02 0230
gene id: 284813:ECU02_0230
uniprot id: Q8SSI5
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

284813:ECU01 0650
gene id: 284813:ECU01_0650
uniprot id: Q8SSL7
names: Cofactor
names: Developmental Stage
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.
messages: Expressed in late sporogonial stages.

284813:ECU05 1250
gene id: 284813:ECU05_1250
uniprot id: Q95ZE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

284813:ECU10 1575
gene id: 284813:ECU10_1575
uniprot id: Q8SR05
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS30 family.

284813:ECU05 0780
gene id: 284813:ECU05_0780
uniprot id: Q8SRX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

284813:ECU04 0570
gene id: 284813:ECU04_0570
uniprot id: Q8SVV6
names: Subcellular Location Annotation
messages: Membrane

284813:ECU01 1450
gene id: 284813:ECU01_1450
uniprot id: O62583
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).

284813:ECU05 1520
gene id: 284813:ECU05_1520
uniprot id: Q8SRT9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

284813:ECU09 1005
gene id: 284813:ECU09_1005
uniprot id: Q8STR6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPH3 family.
messages: Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.
messages: Cytoplasm
messages: Nucleus
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising KTI11/DPH3 and a NADH-dependent reductase, predominantly CBR1. Acts as an electron donor to reduce the Fe-S cluster in DPH1-DPH2 keeping the [4Fe-4S] clusters in the active and reduced state. Restores iron to DPH1-DPH2 iron-sulfur clusters which have degraded from [4Fe-4S] to [3Fe-4S] by donating an iron atom to reform [4Fe-4S] clusters, in a manner dependent on the presence of elongation factor 2 and SAM. Associates with the elongator complex and is required for tRNA Wobble base modifications mediated by the elongator complex. The elongator complex is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine).
messages: The DPH-type metal-binding (MB) domain can also bind zinc. However, iron is the physiological binding partner as zinc binding impairs the protein electron donor function.

284813:ECU10 1440
gene id: 284813:ECU10_1440
uniprot id: Q8SUB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

284813:ECU05 1390
gene id: 284813:ECU05_1390
uniprot id: Q8SVH0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

284813:ECU04 1340
gene id: 284813:ECU04_1340
uniprot id: Q8SVR8
names: Similarity
messages: Belongs to the CBF/MAK21 family.

284813:ECU03 1350
gene id: 284813:ECU03_1350
uniprot id: Q8SS81
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

284813:ECU11 2000
gene id: 284813:ECU11_2000
uniprot id: Q8SQR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Nucleus

284813:ECU06 0460
gene id: 284813:ECU06_0460
uniprot id: Q8SRR9
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

284813:ECU09 1500
gene id: 284813:ECU09_1500
uniprot id: Q8STN5
names: Similarity
messages: Belongs to the methyltransferase superfamily.

284813:ECU11 0480
gene id: 284813:ECU11_0480
uniprot id: Q8SQI7
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

284813:ECU11 1780
gene id: 284813:ECU11_1780
uniprot id: Q8SQS1
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDPGP type 1 family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU08 0570
gene id: 284813:ECU08_0570
uniprot id: Q8SUR8
names: Similarity
messages: Belongs to the CWC16 family.

284813:ECU07 0450
gene id: 284813:ECU07_0450
uniprot id: Q8SV30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

284813:ECU10 0420
gene id: 284813:ECU10_0420
uniprot id: Q8SUG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP transporter involved in the uptake of ATP from the host cell cytoplasm. Provides the microsporidian cell with host ATP in exchange for ADP. This is an obligate exchange system. This energy acquiring activity is an important component of microsporidian parasitism.
messages: Belongs to the ADP/ATP translocase tlc family.
messages: Cell membrane

284813:ECU07 1460
gene id: 284813:ECU07_1460
uniprot id: Q8SRH5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.

284813:ECU11 0230
gene id: 284813:ECU11_0230
uniprot id: Q8SQZ1
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.

284813:ECU09 0090
gene id: 284813:ECU09_0090
uniprot id: Q8SQQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

284813:ECU03 0530
gene id: 284813:ECU03_0530
uniprot id: Q8SW56
names: Similarity
messages: Belongs to the synaptobrevin family.

284813:ECU03 0590
gene id: 284813:ECU03_0590
uniprot id: Q8SW52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

284813:ECU05 1600
gene id: 284813:ECU05_1600
uniprot id: Q8STJ2
names: Similarity
messages: To E.cuniculi ECU03_0120.

284813:ECU04 1015
gene id: 284813:ECU04_1015
uniprot id: Q8SS34
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

284813:ECU07 0800
gene id: 284813:ECU07_0800
uniprot id: Q8SRJ8
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

284813:ECU11 1080
gene id: 284813:ECU11_1080
uniprot id: Q8SQV7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

284813:ECU10 0400
gene id: 284813:ECU10_0400
uniprot id: Q8SR65
names: Developmental Stage
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Expressed in late sporogonial stages.

284813:ECU03 0305
gene id: 284813:ECU03_0305
uniprot id: Q8SSC3
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

284813:ECU04 0260
gene id: 284813:ECU04_0260
uniprot id: Q8SVX7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

284813:ECU01 1170
gene id: 284813:ECU01_1170
uniprot id: Q8SWI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

284813:ECU10 1850
gene id: 284813:ECU10_1850
uniprot id: Q8SU92
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU03 0490
gene id: 284813:ECU03_0490
uniprot id: Q8SSB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

284813:ECU07 0890
gene id: 284813:ECU07_0890
uniprot id: Q8SV03
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Monomer.
messages: Nucleus
messages: Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1). This promotes the activity of RNA polymerase II.

284813:ECU05 1680
gene id: 284813:ECU05_1680
uniprot id: Q8STA9
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU10 1590
gene id: 284813:ECU10_1590
uniprot id: Q8SR03
names: Similarity
messages: Belongs to the cytidylyltransferase family.

284813:ECU09 1200
gene id: 284813:ECU09_1200
uniprot id: Q8SQM5
names: Developmental Stage
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: Component of the eIF4F complex, which composition varies with external and internal environmental conditions. It is composed of at least eIF4A, eIF4E and eIF4G (By similarity).
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284813:ECU10 1420
gene id: 284813:ECU10_1420
uniprot id: Q8SR13
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a regulatory subunit of the 26S proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH (By similarity).
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel (By similarity).

284813:ECU04 1060
gene id: 284813:ECU04_1060
uniprot id: Q8SS32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.

284813:ECU05 0320
gene id: 284813:ECU05_0320
uniprot id: Q8SRZ8
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

284813:ECU11 1340
gene id: 284813:ECU11_1340
uniprot id: Q8SQU5
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Expressed in late sporogonial stages.
messages: Membrane

284813:ECU08 0210
gene id: 284813:ECU08_0210
uniprot id: Q8SRF6
names: Function
names: Similarity
messages: Belongs to the WD repeat SEC31 family.
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.

284813:ECU04 0970
gene id: 284813:ECU04_0970
uniprot id: Q8SVT6
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU08 1290
gene id: 284813:ECU08_1290
uniprot id: Q8SRA3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

284813:ECU02 1240
gene id: 284813:ECU02_1240
uniprot id: Q8SSE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus

284813:ECU07 0400
gene id: 284813:ECU07_0400
uniprot id: Q8SV33
names: Developmental Stage
names: Subcellular Location Annotation
messages: Expressed in late sporogonial stages.
messages: Golgi apparatus

284813:ECU07 0530
gene id: 284813:ECU07_0530
uniprot id: Q8SV25
names: Developmental Stage
names: Subcellular Location Annotation
messages: Expressed in late sporogonial stages.
messages: Membrane

284813:ECU05 1240
gene id: 284813:ECU05_1240
uniprot id: Q8SRV2
names: Function
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.

284813:ECU02 0880
gene id: 284813:ECU02_0880
uniprot id: Q8SWC9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

284813:ECU08 1960
gene id: 284813:ECU08_1960
uniprot id: Q8SR85
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC7 subfamily.
messages: Serine/threonine-protein kinase. Needed for the initiation of DNA synthesis during mitosis as well as for synaptonemal complex formation and commitment to recombination during meiosis (By similarity).

284813:ECU08 1550
gene id: 284813:ECU08_1550
uniprot id: Q8SUL4
names: Developmental Stage
names: Subcellular Location Annotation
messages: Expressed in late sporogonial stages.
messages: Membrane

284813:ECU05 0030
gene id: 284813:ECU05_0030
uniprot id: P0CS96
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU09 0860
gene id: 284813:ECU09_0860
uniprot id: Q8STS6
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

284813:ECU06 0120
gene id: 284813:ECU06_0120
uniprot id: Q8SVF0
names: Similarity
messages: Belongs to the transketolase family.

284813:ECU03 1240
gene id: 284813:ECU03_1240
uniprot id: Q8SW15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

284813:ECU08 0340
gene id: 284813:ECU08_0340
uniprot id: Q8SRE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

284813:ECU08 1060
gene id: 284813:ECU08_1060
uniprot id: Q8SRB3
names: Developmental Stage
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Expressed in late sporogonial stages.

284813:ECU10 0090
gene id: 284813:ECU10_0090
uniprot id: Q8SQH8
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Expressed in late sporogonial stages.
messages: GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

284813:ECU08 0830
gene id: 284813:ECU08_0830
uniprot id: Q8SRC2
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

284813:ECU11 1860
gene id: 284813:ECU11_1860
uniprot id: Q8SU01
names: Subcellular Location Annotation
messages: Membrane

284813:ECU10 0340
gene id: 284813:ECU10_0340
uniprot id: Q8SR69
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Involved in osmoadaptation.

284813:ECU06 1520
gene id: 284813:ECU06_1520
uniprot id: Q8SRM8
names: Similarity
messages: Belongs to the DNA polymerase type-B-like family.

284813:ECU06 1550
gene id: 284813:ECU06_1550
uniprot id: Q8SRM6
names: Similarity
messages: Belongs to the WD repeat rae1 family.

284813:ECU01 0820
gene id: 284813:ECU01_0820
uniprot id: Q8SWL3
names: Developmental Stage
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Expressed during merogony and a large part of sporogony.
messages: Heparin-binding motifs (HBMs) are characterized by an XBBXBX or XBBBXXBX sequence, where X is any neutral amino acid and B is a positively charged basic amino acid, and are defined as the consensus sequence necessary for protein-heparin interactions. HBM1 motif is necessary for spore adherence to host cells.
messages: Spore wall
messages: Spore wall protein involved in the adhesion to host cells surface glycoaminoglycans (GAGs). Microsporidian spore adherence is an integral part of activation and host cell invasion which requires the extrusion at the spore apex of a very long and coiled structure, the polar tube, through which the sporoplasm is pushed to enter into the potential host cell.
messages: perispore

284813:ECU08 0700
gene id: 284813:ECU08_0700
uniprot id: Q8SRC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

284813:ECU04 0650
gene id: 284813:ECU04_0650
uniprot id: Q8SVV2
names: Similarity
messages: Belongs to the SWI5/SAE3 family.

284813:ECU11 0880
gene id: 284813:ECU11_0880
uniprot id: Q8SQI7
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

284813:ECU10 0410
gene id: 284813:ECU10_0410
uniprot id: Q8SR64
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

284813:ECU06 0740
gene id: 284813:ECU06_0740
uniprot id: Q8SRR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/KNOX homeobox family.
messages: Nucleus

284813:ECU09 1400
gene id: 284813:ECU09_1400
uniprot id: Q8STP1
names: Developmental Stage
messages: Expressed in late sporogonial stages.

284813:ECU09 1290
gene id: 284813:ECU09_1290
uniprot id: Q8STP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP11 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

284813:ECU04 1550
gene id: 284813:ECU04_1550
uniprot id: Q8SVQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fungal TPase family.
messages: First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.
messages: Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.
messages: Nucleus

284813:ECU06 0510
gene id: 284813:ECU06_0510
uniprot id: Q8SRR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Component of the T-complex protein 1 (TCP1) complex.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.

284813:ECU01 1390
gene id: 284813:ECU01_1390
uniprot id: Q8SSI7
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chitin synthase family. Class IV subfamily.
messages: Cell membrane
messages: Expression is low in meronts, but becomes induced when meronts start to differentiate into sporonts.
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

284813:ECU05 0580
gene id: 284813:ECU05_0580
uniprot id: Q8SRY6
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

284813:ECU02 1480
gene id: 284813:ECU02_1480
uniprot id: Q8SW89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC24 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

284813:ECU11 1320
gene id: 284813:ECU11_1320
uniprot id: Q8SU25
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Expressed in late sporogonial stages.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: cis-Golgi network

284813:ECU11 1440
gene id: 284813:ECU11_1440
uniprot id: Q8MTP3
names: Developmental Stage
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Found in spores. Expression is high during polar tube formation.
messages: Interacts with PTP1 and PTP2.
messages: Involved in the sporoblast-to-spore polar tube biogenesis. Plays a role in the control of the polar tube extrusion as part of a specific response to ionic stimuli.
messages: Spore polar tube

284813:ECU03 1380
gene id: 284813:ECU03_1380
uniprot id: Q8SW06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm

284813:ECU07 0920
gene id: 284813:ECU07_0920
uniprot id: Q8SV00
names: Developmental Stage
names: Subcellular Location Annotation
messages: Expressed in late sporogonial stages.
messages: Secreted

284813:ECU06 0940
gene id: 284813:ECU06_0940
uniprot id: Q8SVA6
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Expressed in late sporogonial stages.
messages: Homodimer.
messages: Peroxisome

284813:ECU02 0780
gene id: 284813:ECU02_0780
uniprot id: Q8SSF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus

284813:ECU10 0210
gene id: 284813:ECU10_0210
uniprot id: Q8SR78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

284813:ECU10 1450
gene id: 284813:ECU10_1450
uniprot id: Q8SR11
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel (By similarity).
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity (By similarity).

284813:ECU11 0750
gene id: 284813:ECU11_0750
uniprot id: Q8SU53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNO1 family.
messages: Component of the small ribosomal subunit, ribosomal RNA processing complex (SSU RRP complex).
messages: Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species.
messages: nucleolus

284813:ECU06 0600
gene id: 284813:ECU06_0600
uniprot id: Q8SRR5
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

284813:ECU01 1330
gene id: 284813:ECU01_1330
uniprot id: Q8SSI9
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TAF9 family.
messages: Component of the DNA-binding general transcription factor complex TFIID. Component of histone acetyl transferase (HAT) complexes such as SAGA (By similarity).
messages: Expressed in late sporogonial stages.
messages: Functions as a component of the DNA-binding general transcription factor complex TFIID. May also function as a component of transcription regulatory histone acetyl transferase (HAT) complexes such as SAGA. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification, facilitation of DNA opening and initiation of transcription (By similarity).
messages: Nucleus

284813:ECU03 0250
gene id: 284813:ECU03_0250
uniprot id: Q8SW68
names: Similarity
messages: Belongs to the CHS7 family.

284813:ECU01 1560
gene id: 284813:ECU01_1560
uniprot id: P0CT02
uniprot id: P0CT03
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU05 0950
gene id: 284813:ECU05_0950
uniprot id: Q8SRW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

284813:ECU04 0710
gene id: 284813:ECU04_0710
uniprot id: Q8SVU9
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

284813:ECU02 0140
gene id: 284813:ECU02_0140
uniprot id: Q8SSI6
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RANBP1 family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Important for the export of protein containing nuclear export signal (NES) out of the nucleus.
messages: Nucleus

284813:ECU10 1280
gene id: 284813:ECU10_1280
uniprot id: Q8SR19
names: Similarity
messages: Belongs to the PPP phosphatase family.

284813:ECU10 0010
gene id: 284813:ECU10_0010
uniprot id: Q8ST30
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU03 1510
gene id: 284813:ECU03_1510
uniprot id: Q8SVZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

284813:ECU05 0760
gene id: 284813:ECU05_0760
uniprot id: Q8SVK1
names: Similarity
messages: Belongs to the peptidase C48 family.

284813:ECU11 1950
gene id: 284813:ECU11_1950
uniprot id: Q8SQR3
names: Developmental Stage
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Component of the septin complex.
messages: Expressed in late sporogonial stages.
messages: Septins are GTPases involved in cytokinesis. The septins localize to the site of cleavage and act as a structural scaffold that recruits different components involved in diverse processes at specific stages during the cell cycle. Septins are also involved in cell morphogenesis, chitin deposition, cell cycle regulation, cell compartmentalization and spore wall formation (By similarity).

284813:ECU08 1570
gene id: 284813:ECU08_1570
uniprot id: Q8SR96
names: Developmental Stage
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S) (By similarity).
messages: Expressed in late sporogonial stages.

284813:ECU10 0250
gene id: 284813:ECU10_0250
uniprot id: Q8SR75
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template (By similarity).
messages: Nucleus
messages: The binding of ribonucleoside triphosphate to the RNA polymerase II transcribing complex probably involves a two-step mechanism. The initial binding seems to occur at the entry (E) site and involves a magnesium ion coordinated by three conserved aspartate residues of the two largest RNA Pol II subunits (By similarity).

284813:ECU09 0310
gene id: 284813:ECU09_0310
uniprot id: Q8SQQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

284813:ECU10 0830
gene id: 284813:ECU10_0830
uniprot id: Q8SR41
names: Similarity
messages: Belongs to the MAK16 family.

284813:ECU10 1020
gene id: 284813:ECU10_1020
uniprot id: Q8SUD7
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU03 0920
gene id: 284813:ECU03_0920
uniprot id: Q8SS95
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.

284813:ECU06 0620
gene id: 284813:ECU06_0620
uniprot id: Q8SRR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

284813:ECU07 0750
gene id: 284813:ECU07_0750
uniprot id: Q8SRK1
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
messages: Component of the HAT-B complex.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: Regulatory subunit of the histone acetylase B (HAT-B) complex. The complex acetylates histone H4 which is required for telomeric silencing (By similarity).

284813:ECU11 1810
gene id: 284813:ECU11_1810
uniprot id: Q8SQS0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

284813:ECU09 0970
gene id: 284813:ECU09_0970
uniprot id: Q8STR8
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU08 0270
gene id: 284813:ECU08_0270
uniprot id: Q8SUT4
names: Developmental Stage
messages: Expressed in late sporogonial stages.

284813:ECU08 1920
gene id: 284813:ECU08_1920
uniprot id: Q8SR86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
messages: Cyclin-dependent kinase that acts as a master regulator of the mitotic and meiotic cell cycles.
messages: Nucleus

284813:ECU11 0070
gene id: 284813:ECU11_0070
uniprot id: Q8STG4
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU02 0930
gene id: 284813:ECU02_0930
uniprot id: Q8SWC5
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU03 0460
gene id: 284813:ECU03_0460
uniprot id: Q8SSB6
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

284813:ECU11 2020
gene id: 284813:ECU11_2020
uniprot id: Q8SQQ9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

284813:ECU11 0400
gene id: 284813:ECU11_0400
uniprot id: Q8SU73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

284813:ECU11 2100
gene id: 284813:ECU11_2100
uniprot id: Q8ST89
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU11 0910
gene id: 284813:ECU11_0910
uniprot id: Q8SU48
names: Subcellular Location Annotation
messages: nucleolus

284813:ECU09 1170
gene id: 284813:ECU09_1170
uniprot id: Q8STQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Membrane

284813:ECU09 1275
gene id: 284813:ECU09_1275
uniprot id: Q8SQM2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

284813:ECU07 0050
gene id: 284813:ECU07_0050
uniprot id: Q8STE6
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU07 1610
gene id: 284813:ECU07_1610
uniprot id: Q8SUV4
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

284813:ECU03 1460
gene id: 284813:ECU03_1460
uniprot id: Q8SS77
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation of histone H3 leads to transcriptional activation.
messages: Belongs to the histone H3 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Mono-, di- and trimethylated to form H3K4me1/2/3. H3K4me activates gene expression by regulating transcription elongation and plays a role in telomere length maintenance. H3K4me enrichment correlates with transcription levels, and occurs in a 5' to 3' gradient with H3K4me3 enrichment at the 5'-end of genes, shifting to H3K4me2 and then H3K4me1. H3K36me represses gene expression (By similarity).
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H3K4me1/2/3 = mono-, di- and trimethylated Lys-5; H3K9ac = acetylated Lys-10; H3K9me1 = monomethylated Lys-10; H3K14ac = acetylated Lys-15; H3K14me2 = dimethylated Lys-15; H3K18ac = acetylated Lys-19; H3K18me1 = monomethylated Lys-19; H3K23ac = acetylated Lys-24; H3K23me1 = monomethylated Lys-24; H3K27ac = acetylated Lys-28; H3K27me1/2/3 = mono-, di- and trimethylated Lys-28; H3K36ac = acetylated Lys-39; H3K36me1/2/3 = mono-, di- and trimethylated Lys-39; H3K56ac = acetylated Lys-58.

284813:ECU10 0750
gene id: 284813:ECU10_0750
uniprot id: Q8SR45
names: Cofactor
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU10 0880
gene id: 284813:ECU10_0880
uniprot id: Q8SUE5
names: Developmental Stage
names: Subcellular Location Annotation
messages: Expressed in late sporogonial stages.
messages: Membrane

284813:ECU09 0430
gene id: 284813:ECU09_0430
uniprot id: Q8SQP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

284813:ECU09 0450
gene id: 284813:ECU09_0450
uniprot id: Q8SQP3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation of histone H3 leads to transcriptional activation.
messages: Belongs to the histone H3 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Mono-, di- and trimethylated to form H3K4me1/2/3. H3K4me activates gene expression by regulating transcription elongation and plays a role in telomere length maintenance. H3K4me enrichment correlates with transcription levels, and occurs in a 5' to 3' gradient with H3K4me3 enrichment at the 5'-end of genes, shifting to H3K4me2 and then H3K4me1 (By similarity).
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H3K4me1/2/3 = mono-, di- and trimethylated Lys-5; H3K9ac = acetylated Lys-10; H3K9me1 = monomethylated Lys-10; H3K14ac = acetylated Lys-15; H3K14me2 = dimethylated Lys-15; H3K18ac = acetylated Lys-19; H3K18me1 = monomethylated Lys-19; H3K23ac = acetylated Lys-24; H3K23me1 = monomethylated Lys-24; H3K56ac = acetylated Lys-56; H3K64ac = acetylated Lys-64.

284813:ECU03 1060
gene id: 284813:ECU03_1060
uniprot id: Q8SW24
names: Subcellular Location Annotation
messages: Membrane

284813:ECU09 0660
gene id: 284813:ECU09_0660
uniprot id: Q8STT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane
messages: Regulates also the sphingolipid metabolism.

284813:ECU02 1400
gene id: 284813:ECU02_1400
uniprot id: Q8SW96
names: Function
messages: Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle.

284813:ECU04 1390
gene id: 284813:ECU04_1390
uniprot id: Q8SVR4
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU01 0970
gene id: 284813:ECU01_0970
uniprot id: Q8SSK6
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldo/keto reductase family.
messages: Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU01 1530
gene id: 284813:ECU01_1530
uniprot id: Q8STE0
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU04 0400
gene id: 284813:ECU04_0400
uniprot id: Q8SS62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HSF family.
messages: DNA-binding transcription factor that specifically binds heat shock promoter elements (HSE) and activates transcription.
messages: Homotrimer (By similarity). Homotrimerization increases the affinity of HSF1 to DNA (By similarity).
messages: Nucleus

284813:ECU02 0670
gene id: 284813:ECU02_0670
uniprot id: Q8SSG7
names: Similarity
messages: Belongs to the DEAD box helicase family.

284813:ECU08 2120
gene id: 284813:ECU08_2120
uniprot id: Q8STG8
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU11 0780
gene id: 284813:ECU11_0780
uniprot id: Q8SQX3
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS7 family.
messages: Component of the small ribosomal subunit.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU04 0060
gene id: 284813:ECU04_0060
uniprot id: Q8STG8
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU09 0710
gene id: 284813:ECU09_0710
uniprot id: Q8STT6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

284813:ECU05 1210
gene id: 284813:ECU05_1210
uniprot id: Q8SRV4
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.

284813:ECU06 0250
gene id: 284813:ECU06_0250
uniprot id: O76942
names: Developmental Stage
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Found in spores. Expression is high during polar tube formation.
messages: Interacts with PTP2 and PTP3.
messages: Involved with PTP2 and PTP3 in the formation of the polar tube through which the infectious agent is passed on to the host cell. Accounts for at least 70 percent of the mass of the polar tube.
messages: Spore polar tube

284813:ECU01 0510
gene id: 284813:ECU01_0510
uniprot id: Q8SSM2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NifU family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the core Fe-S cluster (ISC) assembly machinery.
messages: Mitosome matrix
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitosomes, which is required for maturation of both [2Fe-2S] and [4Fe-4S] proteins (PubMed:18311129). First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster assembly on ISU1 depends on the function of the cysteine desulfurase complex NFS1-ISD11, which serves as the sulfur donor for cluster synthesis, the iron-binding protein frataxin as the putative iron donor, and the electron transfer chain comprised of ferredoxin reductase and ferredoxin, which receive their electrons from NADH (By similarity).

284813:ECU02 1380
gene id: 284813:ECU02_1380
uniprot id: Q8SSD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

284813:ECU01 0050
gene id: 284813:ECU01_0050
uniprot id: P0CT02
uniprot id: P0CT03
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU03 0130
gene id: 284813:ECU03_0130
uniprot id: Q8SW74
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU03 1250
gene id: 284813:ECU03_1250
uniprot id: Q8SW14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

284813:ECU02 1210
gene id: 284813:ECU02_1210
uniprot id: Q8SSE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Cytoplasm

284813:ECU10 1480
gene id: 284813:ECU10_1480
uniprot id: Q8SR09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/KNOX homeobox family.
messages: Nucleus

284813:ECU05 0390
gene id: 284813:ECU05_0390
uniprot id: Q8SRZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

284813:ECU11 0760
gene id: 284813:ECU11_0760
uniprot id: Q8SQX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

284813:ECU07 0840
gene id: 284813:ECU07_0840
uniprot id: Q8SRJ5
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.

284813:ECU06 0730
gene id: 284813:ECU06_0730
uniprot id: Q8SRR2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Heterodimer of a large and a small subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).

284813:ECU05 0690
gene id: 284813:ECU05_0690
uniprot id: Q8SVK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Membrane

284813:ECU09 1360
gene id: 284813:ECU09_1360
uniprot id: Q8SQL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Nucleus

284813:ECU06 0050
gene id: 284813:ECU06_0050
uniprot id: Q8SVF7
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU02 1410
gene id: 284813:ECU02_1410
uniprot id: Q8SSD5
names: Similarity
messages: Belongs to the Rab GDI family.

284813:ECU08 0250
gene id: 284813:ECU08_0250
uniprot id: Q8SRF3
names: Similarity
messages: Belongs to the V-ATPase H subunit family.

284813:ECU10 0030
gene id: 284813:ECU10_0030
uniprot id: Q8STJ1
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU10 0160
gene id: 284813:ECU10_0160
uniprot id: Q8SR87
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

284813:ECU01 0460
gene id: 284813:ECU01_0460
uniprot id: Q8SWN8
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
messages: Belongs to the actin family.
messages: Expressed in late sporogonial stages.
messages: cytoskeleton

284813:ECU03 0220
gene id: 284813:ECU03_0220
uniprot id: Q8SSC9
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Component of the T-complex protein 1 (TCP1) complex.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.

284813:ECU10 1680
gene id: 284813:ECU10_1680
uniprot id: Q8SR01
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase required for ribosome biogenesis. Involved in the release of U14 snoRNA in pre-ribosomal complexes. Required for pre-rRNA cleavage at site A2 (By similarity).
messages: Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily.
messages: Interacts with the U3 and U14 snoRNAs. Associates with pre-ribosomal complexes (By similarity).
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284813:ECU07 1890
gene id: 284813:ECU07_1890
uniprot id: Q8ST30
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU07 1170
gene id: 284813:ECU07_1170
uniprot id: Q8SUY1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

284813:ECU10 1000
gene id: 284813:ECU10_1000
uniprot id: Q8SR35
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

284813:ECU11 0770
gene id: 284813:ECU11_0770
uniprot id: Q8SU52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover (By similarity). Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA (By similarity).
messages: Belongs to the CCR4/nocturin family.
messages: Component of the CCR4-NOT core complex.
messages: Cytoplasm
messages: Nucleus

284813:ECU11 1150
gene id: 284813:ECU11_1150
uniprot id: Q8SU34
names: Subcellular Location Annotation
messages: Membrane

284813:ECU07 1750
gene id: 284813:ECU07_1750
uniprot id: Q8SRG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

284813:ECU04 1610
gene id: 284813:ECU04_1610
uniprot id: Q8SVP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic initiation factor 4G family.
messages: Component of the eIF4F complex, which composition varies with external and internal environmental conditions.
messages: Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.
messages: Cytoplasm

284813:ECU06 1300
gene id: 284813:ECU06_1300
uniprot id: Q8SV83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

284813:ECU10 1240
gene id: 284813:ECU10_1240
uniprot id: Q8SR21
names: Subcellular Location Annotation
messages: Cytoplasm

284813:ECU06 1080i
gene id: 284813:ECU06_1080i
uniprot id: Q8SRP5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL19 family.

284813:ECU09 1250
gene id: 284813:ECU09_1250
uniprot id: Q8SQM3
names: Developmental Stage
names: Similarity
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Expressed in late sporogonial stages.

284813:ECU05 0275
gene id: 284813:ECU05_0275
uniprot id: Q8SS03
names: Similarity
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.

284813:ECU07 0110
gene id: 284813:ECU07_0110
uniprot id: Q8SRM2
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Component of the large ribosomal subunit.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Plays an important role in the elongation step of protein synthesis.

284813:ECU02 1290
gene id: 284813:ECU02_1290
uniprot id: Q8SWA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm

284813:ECU10 1470
gene id: 284813:ECU10_1470
uniprot id: Q8SUB7
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU11 2060
gene id: 284813:ECU11_2060
uniprot id: Q8SQQ7
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Component of the large ribosomal subunit.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU10 1580
gene id: 284813:ECU10_1580
uniprot id: Q8SR04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

284813:ECU11 0040
gene id: 284813:ECU11_0040
uniprot id: Q8ST65
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU09 0520
gene id: 284813:ECU09_0520
uniprot id: Q8STV2
names: Similarity
messages: Belongs to the NOC2 family.

284813:ECU07 1500
gene id: 284813:ECU07_1500
uniprot id: Q8SRH4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

284813:ECU01 0110
gene id: 284813:ECU01_0110
uniprot id: Q8STB5
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU08 0040
gene id: 284813:ECU08_0040
uniprot id: Q8STB5
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU01 0130
gene id: 284813:ECU01_0130
uniprot id: Q8ST53
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU06 0900i
gene id: 284813:ECU06_0900i
uniprot id: Q8SRQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

284813:ECU02 0290
gene id: 284813:ECU02_0290
uniprot id: Q8SSI2
names: Similarity
messages: Belongs to the activator 1 small subunits family.

284813:ECU05 1190
gene id: 284813:ECU05_1190
uniprot id: Q8SRV5
names: Caution
names: Similarity
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
messages: Lacks transmembrane domains and is probably not involved in transport.

284813:ECU10 0050
gene id: 284813:ECU10_0050
uniprot id: Q8ST44
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU08 1450
gene id: 284813:ECU08_1450
uniprot id: Q8SR99
names: Developmental Stage
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
messages: Expressed in late sporogonial stages.

284813:ECU01 1115
gene id: 284813:ECU01_1115
uniprot id: Q8SWJ3
names: Similarity
messages: Belongs to the cytochrome b5 family.

284813:ECU08 1610
gene id: 284813:ECU08_1610
uniprot id: Q8SUL0
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the 60S ribosomal subunit.
messages: Belongs to the SDO1/SBDS family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: May be involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes.

284813:ECU06 1700
gene id: 284813:ECU06_1700
uniprot id: Q8ST81
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU10 1870
gene id: 284813:ECU10_1870
uniprot id: P0CS97
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU01 0870
gene id: 284813:ECU01_0870
uniprot id: Q8SSL0
names: Developmental Stage
names: Similarity
messages: Expressed in late sporogonial stages.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

284813:ECU02 0480
gene id: 284813:ECU02_0480
uniprot id: Q8SSH5
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a regulatory subunit of the 26S proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH (By similarity).
messages: Belongs to the proteasome subunit S1 family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel (By similarity).

284813:ECU11 0620
gene id: 284813:ECU11_0620
uniprot id: Q95ZE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

284813:ECU03 0290
gene id: 284813:ECU03_0290
uniprot id: Q8SSC4
names: Domain
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template. At the start of transcription, a single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol II. A bridging helix emanates from RPB1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol II by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition. During transcription elongation, Pol II moves on the template as the transcript elongates. Elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of Pol II largest subunit (RPB1), which serves as a platform for assembly of factors that regulate transcription initiation, elongation, termination and mRNA processing (By similarity).
messages: Nucleus
messages: The C-terminal domain (CTD) serves as a platform for assembly of factors that regulate transcription initiation, elongation, termination and mRNA processing.
messages: The binding of ribonucleoside triphosphate to the RNA polymerase II transcribing complex probably involves a two-step mechanism. The initial binding seems to occur at the entry (E) site and involves a magnesium ion temporarily coordinated by three conserved aspartate residues of the two largest RNA Pol II subunits. The ribonucleoside triphosphate is transferred by a rotation to the nucleotide addition (A) site for pairing with the template DNA. The catalytic A site involves three conserved aspartate residues of the RNA Pol II largest subunit which permanently coordinate a second magnesium ion.
messages: The tandem 7 residues repeats in the C-terminal domain (CTD) can be highly phosphorylated. The phosphorylation activates Pol II. Phosphorylation occurs mainly at residues 'Ser-2' and 'Ser-5' of the heptapeptide repeat. The phosphorylation state is believed to result from the balanced action of site-specific CTD kinases and phosphatase, and a 'CTD code' that specifies the position of Pol II within the transcription cycle has been proposed (By similarity).

284813:ECU08 0630
gene id: 284813:ECU08_0630
uniprot id: Q8SRD5
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

284813:ECU09 0060
gene id: 284813:ECU09_0060
uniprot id: Q8STY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Membrane

284813:ECU06 0930
gene id: 284813:ECU06_0930
uniprot id: Q8SRQ0
names: Subcellular Location Annotation
messages: Membrane

284813:ECU10 0140
gene id: 284813:ECU10_0140
uniprot id: Q8SR82
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

284813:ECU01 0170
gene id: 284813:ECU01_0170
uniprot id: O62583
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).

284813:ECU07 0820
gene id: 284813:ECU07_0820
uniprot id: Q8SRJ7
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the large ribosomal subunit.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

284813:ECU10 1300
gene id: 284813:ECU10_1300
uniprot id: Q8SR18
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

284813:ECU02 1430
gene id: 284813:ECU02_1430
uniprot id: Q8SW94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

284813:ECU08 1200
gene id: 284813:ECU08_1200
uniprot id: Q8SUN7
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

284813:ECU06 1680
gene id: 284813:ECU06_1680
uniprot id: Q8SV57
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU02 0100
gene id: 284813:ECU02_0100
uniprot id: Q8SWH2
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU03 1540
gene id: 284813:ECU03_1540
uniprot id: Q8SVZ4
names: Subcellular Location Annotation
messages: Membrane

284813:ECU09 1610
gene id: 284813:ECU09_1610
uniprot id: Q8STM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

284813:ECU05 1040
gene id: 284813:ECU05_1040
uniprot id: Q8SVI9
names: Developmental Stage
messages: Expressed in late sporogonial stages.

284813:ECU03 0600
gene id: 284813:ECU03_0600
uniprot id: Q8SW51
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU11 1460
gene id: 284813:ECU11_1460
uniprot id: Q8SQT7
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU05 0040
gene id: 284813:ECU05_0040
uniprot id: Q8STE8
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU08 2100
gene id: 284813:ECU08_2100
uniprot id: Q8ST97
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU11 0820
gene id: 284813:ECU11_0820
uniprot id: Q8SQX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Required both for recombination and for the repair of DNA damage caused by X-rays.

284813:ECU06 0360
gene id: 284813:ECU06_0360
uniprot id: Q8SRS2
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU01 0800
gene id: 284813:ECU01_0800
uniprot id: Q8SSL2
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Component of the trehalose synthase complex.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Synthase catalytic subunit of the trehalose synthase complex that catalyzes the production of trehalose from glucose-6-phosphate and UDP-alpha-D-glucose in a two step process. Can function independently of the complex (By similarity).

284813:ECU08 1430
gene id: 284813:ECU08_1430
uniprot id: Q8SUM3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

284813:ECU03 0500
gene id: 284813:ECU03_0500
uniprot id: Q8SSB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.

284813:ECU01 0430
gene id: 284813:ECU01_0430
uniprot id: Q8SSM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
messages: Nucleus

284813:ECU10 1170
gene id: 284813:ECU10_1170
uniprot id: Q8SR26
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU04 0740
gene id: 284813:ECU04_0740
uniprot id: Q8SS49
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL22 family.
messages: Component of the large ribosomal subunit.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU09 0770
gene id: 284813:ECU09_0770
uniprot id: Q8SQN5
names: Similarity
messages: Belongs to the DNA polymerase delta/II small subunit family.

284813:ECU06 0670
gene id: 284813:ECU06_0670
uniprot id: Q8SVC0
names: Developmental Stage
messages: Expressed in late sporogonial stages.

284813:ECU02 1180
gene id: 284813:ECU02_1180
uniprot id: Q8SWA8
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU06 0030
gene id: 284813:ECU06_0030
uniprot id: Q8STJ4
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU05 1590
gene id: 284813:ECU05_1590
uniprot id: Q8SQI1
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA glycosylase MPG family.
messages: Expressed in late sporogonial stages.
messages: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
messages: Nucleus

284813:ECU05 0885
gene id: 284813:ECU05_0885
uniprot id: Q8SRW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma.
messages: Necessary for protein translocation in the endoplasmic reticulum.

284813:ECU08 1190
gene id: 284813:ECU08_1190
uniprot id: Q8SUN8
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

284813:ECU10 1080
gene id: 284813:ECU10_1080
uniprot id: Q8SR32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

284813:ECU01 1240
gene id: 284813:ECU01_1240
uniprot id: Q8SWI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

284813:ECU11 1830
gene id: 284813:ECU11_1830
uniprot id: Q8SQR8
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Required for normal growth at various temperatures.

284813:ECU04 0890
gene id: 284813:ECU04_0890
uniprot id: Q8SS41
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

284813:ECU02 0310
gene id: 284813:ECU02_0310
uniprot id: Q8SWF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with pre-60S ribosomal particles; released from the pre-60S particle very early in the cytoplasm.
messages: Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Involved in pre-60S ribosomal particles maturation by promoting the nuclear export of the 60S ribosome.
messages: Nucleus

284813:ECU11 2070
gene id: 284813:ECU11_2070
uniprot id: Q8SQH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

284813:ECU08 1850
gene id: 284813:ECU08_1850
uniprot id: Q8SR89
names: Developmental Stage
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis (By similarity).
messages: Expressed in late sporogonial stages.

284813:ECU10 1770i
gene id: 284813:ECU10_1770i
uniprot id: Q8SQZ7
names: Cofactor
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M17 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Homohexamer.
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity).

284813:ECU04 0780
gene id: 284813:ECU04_0780
uniprot id: Q8SS47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: nucleolus

284813:ECU09 0670
gene id: 284813:ECU09_0670
uniprot id: Q8SQN9
names: Similarity
messages: Belongs to the histone deacetylase family. HD type 1 subfamily.

284813:ECU03 0280
gene id: 284813:ECU03_0280
uniprot id: Q8SSC5
names: Developmental Stage
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Expressed in late sporogonial stages.
messages: Homooctamer.
messages: Plays a central role as a glucosyl donor in cellular metabolic pathways.

284813:ECU09 1520
gene id: 284813:ECU09_1520
uniprot id: Q8STN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

284813:ECU01 0360
gene id: 284813:ECU01_0360
uniprot id: Q8SWP6
names: Similarity
messages: Belongs to the BRX1 family.

284813:ECU09 1800
gene id: 284813:ECU09_1800
uniprot id: Q8SQK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Chromosome
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Nucleus

284813:ECU09 0980
gene id: 284813:ECU09_0980
uniprot id: Q8SQM9
names: Similarity
messages: Belongs to the PPP phosphatase family.

284813:ECU06 0440
gene id: 284813:ECU06_0440
uniprot id: Q8SVD6
names: Similarity
messages: Belongs to the RNase Z family.

284813:ECU03 0340
gene id: 284813:ECU03_0340
uniprot id: Q8SW65
names: Similarity
messages: Belongs to the phosphohexose mutase family.

284813:ECU11 0090
gene id: 284813:ECU11_0090
uniprot id: Q8STF1
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU10 1570i
gene id: 284813:ECU10_1570i
uniprot id: Q8SR06
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

284813:ECU10 0540
gene id: 284813:ECU10_0540
uniprot id: Q8SUF9
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP transporter involved in the uptake of ATP from the host cell cytoplasm. Provides the microsporidian cell with host ATP in exchange for ADP. This is an obligate exchange system. This energy acquiring activity is an important component of microsporidian parasitism.
messages: Belongs to the ADP/ATP translocase tlc family.
messages: Cell membrane
messages: Expressed in all stages of development including spores.

284813:ECU07 1630
gene id: 284813:ECU07_1630
uniprot id: Q8SUV3
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

284813:ECU09 2020
gene id: 284813:ECU09_2020
uniprot id: Q8STE6
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU03 1390
gene id: 284813:ECU03_1390
uniprot id: Q8SW05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Cytoplasm

284813:ECU09 0820
gene id: 284813:ECU09_0820
uniprot id: Q8STS8
names: Developmental Stage
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Component of the septin complex.
messages: Expressed in late sporogonial stages.
messages: Septins are GTPases involved in cytokinesis. The septins localize to the site of cleavage and act as a structural scaffold that recruits different components involved in diverse processes at specific stages during the cell cycle. Septins are also involved in cell morphogenesis, chitin deposition, cell cycle regulation, cell compartmentalization and spore wall formation (By similarity).

284813:ECU10 0900
gene id: 284813:ECU10_0900
uniprot id: Q8SUE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

284813:ECU02 1080
gene id: 284813:ECU02_1080
uniprot id: Q8SWB3
names: Similarity
messages: In the N-terminal section; belongs to the ubiquitin family.

284813:ECU05 0260
gene id: 284813:ECU05_0260
uniprot id: Q8SVM5
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

284813:ECU03 0900
gene id: 284813:ECU03_0900
uniprot id: Q8SS97
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Expressed in late sporogonial stages.
messages: Golgi stack membrane
messages: Involved in vesicular transport between the endoplasmic reticulum and the Golgi.

284813:ECU05 0520
gene id: 284813:ECU05_0520
uniprot id: Q8SVL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

284813:ECU07 0100
gene id: 284813:ECU07_0100
uniprot id: Q8SV52
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

284813:ECU09 1030
gene id: 284813:ECU09_1030
uniprot id: Q8STR3
names: Similarity
messages: Belongs to the cyclin family.

284813:ECU05 0360
gene id: 284813:ECU05_0360
uniprot id: Q8SRZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

284813:ECU06 0080
gene id: 284813:ECU06_0080
uniprot id: Q8SVF4
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU08 0870
gene id: 284813:ECU08_0870
uniprot id: Q8SRB9
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS4 family.
messages: Component of the small ribosomal subunit.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU03 1440
gene id: 284813:ECU03_1440
uniprot id: Q8SS78
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

284813:ECU02 1100
gene id: 284813:ECU02_1100
uniprot id: Q8SSE8
names: Developmental Stage
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Homodimer.
messages: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. The nucleotide-free form of the dimer is found in an open conformation in which the N-termini are not dimerized and the complex is ready for client protein binding. Binding of ATP induces large conformational changes, resulting in the formation of a ring-like closed structure in which the N-terminal domains associate intramolecularly with the middle domain and also dimerize with each other, stimulating their intrinsic ATPase activity and acting as a clamp on the substrate. Finally, ATP hydrolysis results in the release of the substrate. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Required for growth at high temperatures (By similarity).
messages: The TPR repeat-binding motif mediates interaction with TPR repeat-containing proteins.

284813:ECU08 2090
gene id: 284813:ECU08_2090
uniprot id: Q8STE0
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU05 0340
gene id: 284813:ECU05_0340
uniprot id: Q8SVM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

284813:ECU03 0800
gene id: 284813:ECU03_0800
uniprot id: Q8SW42
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.
messages: Cytoplasm

284813:ECU06 0210
gene id: 284813:ECU06_0210
uniprot id: Q8SRT3
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

284813:ECU08 0010
gene id: 284813:ECU08_0010
uniprot id: Q8STE0
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU02 1590
gene id: 284813:ECU02_1590
uniprot id: Q8STG8
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU02 1140
gene id: 284813:ECU02_1140
uniprot id: Q8SSE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284813:ECU07 1830
gene id: 284813:ECU07_1830
uniprot id: Q8SQH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

284813:ECU10 1400
gene id: 284813:ECU10_1400
uniprot id: Q8SUC0
names: Similarity
messages: Belongs to the TIP family.

284813:ECU08 0030
gene id: 284813:ECU08_0030
uniprot id: Q8ST94
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU05 0090
gene id: 284813:ECU05_0090
uniprot id: Q8SS09
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small GTPase superfamily. SAR1 family.
messages: COPII is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex and SAR1.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Expressed in late sporogonial stages.
messages: Golgi apparatus membrane
messages: Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SAR1 controls the coat assembly in a stepwise manner. Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex. These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated transport vesicles. Conversion to SAR1-GDP triggers coat release and recycles COPII subunits (By similarity).

284813:ECU06 1120
gene id: 284813:ECU06_1120
uniprot id: Q8SRP1
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL36 family.
messages: Component of the large ribosomal subunit.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU02 1150
gene id: 284813:ECU02_1150
uniprot id: Q8SSE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

284813:ECU02 0020
gene id: 284813:ECU02_0020
uniprot id: Q8ST35
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU01 1010
gene id: 284813:ECU01_1010
uniprot id: Q8SSK3
names: Developmental Stage
names: Function
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.
messages: Catalyzes the covalent attachment of ubiquitin to other proteins so as to signal them for selective protein degradation. Involved in the formation of multiubiquitin chains.
messages: Expressed in late sporogonial stages.

284813:ECU07 1440
gene id: 284813:ECU07_1440
uniprot id: Q8SUW6
names: Similarity
messages: Belongs to the dopey family.

284813:ECU10 0380
gene id: 284813:ECU10_0380
uniprot id: Q8SR66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: Monomer.
messages: Nucleus
messages: mRNA-capping methyltransferase that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC.

284813:ECU07 1700
gene id: 284813:ECU07_1700
uniprot id: Q8SRG6
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

284813:ECU10 0800
gene id: 284813:ECU10_0800
uniprot id: Q8SUF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.
messages: nucleolus

284813:ECU07 1870
gene id: 284813:ECU07_1870
uniprot id: Q8STJ1
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU05 1540
gene id: 284813:ECU05_1540
uniprot id: Q8SRT7
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a regulatory subunit of the 26S proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH (By similarity).
messages: Belongs to the proteasome subunit S3 family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel (By similarity).

284813:ECU01 1270
gene id: 284813:ECU01_1270
uniprot id: Q8SWI4
names: Developmental Stage
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Expressed during all sporogonic stages.
messages: Membrane
messages: Spore wall
messages: Spore wall component.

284813:ECU05 0730
gene id: 284813:ECU05_0730
uniprot id: Q8SRX7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

284813:ECU07 0900
gene id: 284813:ECU07_0900
uniprot id: Q8SV02
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

284813:ECU02 1060
gene id: 284813:ECU02_1060
uniprot id: Q8SSF0
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.

284813:ECU07 0690
gene id: 284813:ECU07_0690
uniprot id: Q8SV13
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

284813:ECU11 1410
gene id: 284813:ECU11_1410
uniprot id: Q8SU22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EST3 family.
messages: Component of the telomerase complex involved in telomere replication. Stimulates RNA/DNA heteroduplex unwinding which favors the telomere replication by the telomerase.
messages: Nucleus
messages: telomere

284813:ECU10 1860
gene id: 284813:ECU10_1860
uniprot id: Q8SU91
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU01 0100
gene id: 284813:ECU01_0100
uniprot id: Q8ST94
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU09 0640
gene id: 284813:ECU09_0640
uniprot id: Q8SQP0
names: Developmental Stage
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Expressed in late sporogonial stages.
messages: Homotetramer.

284813:ECU11 1350
gene id: 284813:ECU11_1350
uniprot id: Q8SQU4
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

284813:ECU06 0040
gene id: 284813:ECU06_0040
uniprot id: Q8SVF8
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU01 0500
gene id: 284813:ECU01_0500
uniprot id: Q8SWN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284813:ECU10 1210
gene id: 284813:ECU10_1210
uniprot id: Q8SR23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Nucleus

284813:ECU09 1590
gene id: 284813:ECU09_1590
uniprot id: Q8STM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

284813:ECU07 0980
gene id: 284813:ECU07_0980
uniprot id: Q8SUZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1.
messages: Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.
messages: Cytoplasm

284813:ECU11 0370
gene id: 284813:ECU11_0370
uniprot id: Q8SQY8
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

284813:ECU09 0910
gene id: 284813:ECU09_0910
uniprot id: Q8SQN2
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.
messages: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.

284813:ECU11 0570
gene id: 284813:ECU11_0570
uniprot id: Q8SQY3
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a regulatory subunit of the 26S proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH (By similarity).
messages: Belongs to the peptidase M67A family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel (By similarity).

284813:ECU05 1370
gene id: 284813:ECU05_1370
uniprot id: Q8SRU4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

284813:ECU02 1370
gene id: 284813:ECU02_1370
uniprot id: Q8SQJ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

284813:ECU05 1070
gene id: 284813:ECU05_1070
uniprot id: Q8SVI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
messages: Cytoplasm
messages: Required for the final endonucleolytic cleavage at site D converting 20S pre-rRNA into the mature 18S rRNA. Required for the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Despite the protein kinase domain is proposed to act predominantly as an ATPase. Has a role in the cell cycle where it is required for entrance into S-phase and in the control of the onset of anaphase. Appears to also be involved in the maintenance of chromosome stability and correct mitotic segregation (By similarity).

284813:ECU10 0580
gene id: 284813:ECU10_0580
uniprot id: Q8SUF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

284813:ECU11 1380i
gene id: 284813:ECU11_1380i
uniprot id: Q8SQU2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

284813:ECU07 0520
gene id: 284813:ECU07_0520
uniprot id: Q8SRK8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

284813:ECU11 0080
gene id: 284813:ECU11_0080
uniprot id: P0CT00
uniprot id: P0CT01
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU10 0520
gene id: 284813:ECU10_0520
uniprot id: Q8SUG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP transporter involved in the uptake of ATP from the parasite cell cytoplasm into the mitosome matrix. Equilibrates nucleotide pools across a concentration gradient between both sides of the mitosome membrane.
messages: Belongs to the ADP/ATP translocase tlc family.
messages: Mitosome membrane

284813:ECU04 0830
gene id: 284813:ECU04_0830
uniprot id: Q8SVU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

284813:ECU11 0450
gene id: 284813:ECU11_0450
uniprot id: Q8SQY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts on phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol 1,4,5,-trisphosphate.
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
messages: Cytoplasm

284813:ECU10 1290
gene id: 284813:ECU10_1290
uniprot id: Q8SUC6
names: Similarity
messages: Belongs to the MIP18 family.

284813:ECU09 1890
gene id: 284813:ECU09_1890
uniprot id: Q8SQJ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

284813:ECU07 1190
gene id: 284813:ECU07_1190
uniprot id: Q8SRI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

284813:ECU10 1660
gene id: 284813:ECU10_1660
uniprot id: Q9XZV1
names: Developmental Stage
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
messages: Preferentially synthesized during differentiation from meronts to sporonts in early sporogony.
messages: SWP1 is a major antigen recognized during host infection and might be a target for microsporidian infection diagnosis in the case of immunocompetent persons.
messages: Spore wall component.
messages: perispore

284813:ECU10 0020
gene id: 284813:ECU10_0020
uniprot id: Q8STD6
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU01 1490
gene id: 284813:ECU01_1490
uniprot id: Q8STB3
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU05 0060
gene id: 284813:ECU05_0060
uniprot id: Q8SS10
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

284813:ECU11 1550i
gene id: 284813:ECU11_1550i
uniprot id: Q8SQT2
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

284813:ECU11 0190
gene id: 284813:ECU11_0190
uniprot id: Q8SQZ3
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU10 1060
gene id: 284813:ECU10_1060
uniprot id: Q8SR33
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

284813:ECU05 0980
gene id: 284813:ECU05_0980
uniprot id: Q8SVJ1
names: Similarity
messages: Belongs to the APC10 family.

284813:ECU02 1220
gene id: 284813:ECU02_1220
uniprot id: Q8SSE3
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

284813:ECU07 1340
gene id: 284813:ECU07_1340
uniprot id: Q8SRI0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

284813:ECU10 1690
gene id: 284813:ECU10_1690
uniprot id: Q8SUA4
names: Similarity
messages: Belongs to the enolase family.

284813:ECU06 1530
gene id: 284813:ECU06_1530
uniprot id: Q8SRM7
names: Developmental Stage
names: Function
names: Similarity
messages: Belongs to the NDK family.
messages: Expressed in late sporogonial stages.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).

284813:ECU08 1350
gene id: 284813:ECU08_1350
uniprot id: Q8SRA0
names: Subcellular Location Annotation
messages: Membrane

284813:ECU10 1720
gene id: 284813:ECU10_1720
uniprot id: Q8SQZ9
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

284813:ECU11 0200
gene id: 284813:ECU11_0200
uniprot id: Q8SU88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAPC3/SRD2 family.
messages: Nucleus

284813:ECU03 0700
gene id: 284813:ECU03_0700
uniprot id: Q8SW47
names: Similarity
messages: Belongs to the RNR ribonuclease family.

284813:ECU10 1710
gene id: 284813:ECU10_1710
uniprot id: Q8SUA2
names: Similarity
messages: Belongs to the HIT family.

284813:ECU02 1050
gene id: 284813:ECU02_1050
uniprot id: Q8SWB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAC-alpha family.
messages: Cytoplasm
messages: May be involved in mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
messages: Nucleus

284813:ECU01 1410
gene id: 284813:ECU01_1410
uniprot id: Q8SQI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
messages: Membrane

284813:ECU06 1390
gene id: 284813:ECU06_1390
uniprot id: Q8SV76
names: Similarity
messages: Belongs to the NEMF family.

284813:ECU04 0090
gene id: 284813:ECU04_0090
uniprot id: Q8STE0
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU08 0540
gene id: 284813:ECU08_0540
uniprot id: Q8SUS0
names: Developmental Stage
names: Subcellular Location Annotation
messages: Expressed in late sporogonial stages.
messages: Membrane

284813:ECU09 1600
gene id: 284813:ECU09_1600
uniprot id: Q8SQL0
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

284813:ECU10 0690
gene id: 284813:ECU10_0690
uniprot id: Q8SR49
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits. Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA. Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5.8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.
messages: Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
messages: Component of pre-60S ribosomal complexes.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284813:ECU05 0050
gene id: 284813:ECU05_0050
uniprot id: Q8SVN9
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU05 0800
gene id: 284813:ECU05_0800
uniprot id: Q8SVJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

284813:ECU11 1870
gene id: 284813:ECU11_1870
uniprot id: Q8SQR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

284813:ECU10 0280
gene id: 284813:ECU10_0280
uniprot id: Q8SUH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with TAN1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

284813:ECU04 0820
gene id: 284813:ECU04_0820
uniprot id: Q8SS43
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

284813:ECU02 0440
gene id: 284813:ECU02_0440
uniprot id: Q8SSH7
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutathione peroxidase family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.

284813:ECU11 1100
gene id: 284813:ECU11_1100
uniprot id: Q8SQV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

284813:ECU07 0360
gene id: 284813:ECU07_0360
uniprot id: Q8SRL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: Nucleus
messages: Required for high-fidelity chromosome segregation during the later part of each cell cycle. Has a role in attaching the kinetochores to the microtubules and ensuring that sister kinetochores connect to opposite poles. The promotion of bi-orientation is achieved by selectively detaching kinetochore-microtubule attachments that are not under tension (By similarity).
messages: kinetochore
messages: spindle

284813:ECU09 1070
gene id: 284813:ECU09_1070
uniprot id: Q8SQM7
names: Function
names: Similarity
messages: Belongs to the peptidase C13 family.
messages: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

284813:ECU11 0360
gene id: 284813:ECU11_0360
uniprot id: Q8SU76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284813:ECU10 0790
gene id: 284813:ECU10_0790
uniprot id: Q8SUF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

284813:ECU08 1260
gene id: 284813:ECU08_1260
uniprot id: Q8SRA5
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU10 0610
gene id: 284813:ECU10_0610
uniprot id: Q8SUF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: Nucleus
messages: Required for pre-mRNA splicing.

284813:ECU01 1520
gene id: 284813:ECU01_1520
uniprot id: Q8ST67
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU02 1570
gene id: 284813:ECU02_1570
uniprot id: Q8ST97
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU02 0260
gene id: 284813:ECU02_0260
uniprot id: Q8SSI3
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU09 0560
gene id: 284813:ECU09_0560
uniprot id: Q8STU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

284813:ECU08 2010
gene id: 284813:ECU08_2010
uniprot id: Q8SR84
names: Developmental Stage
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Expressed in late sporogonial stages.

284813:ECU08 0090
gene id: 284813:ECU08_0090
uniprot id: Q8SRG2
names: Similarity
messages: Belongs to the thymidylate synthase family.

284813:ECU09 0930
gene id: 284813:ECU09_0930
uniprot id: Q8STS1
names: Similarity
messages: Belongs to the RAD52 family.

284813:ECU01 0630
gene id: 284813:ECU01_0630
uniprot id: Q8SWM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
messages: Protein kinase required for the cell cycle where it is involved in mitotic exit. Required to form a bipolar spindle, the actin ring and septum. Functions upstream of the whole septum formation pathway, including actin ring formation (regulated by late septation genes) and septal material deposition (regulated by early septation genes). Behaves as a 'septum-promoting factor', and could also be involved in inducing other late events of cell division (By similarity).
messages: spindle pole body

284813:ECU06 0190
gene id: 284813:ECU06_0190
uniprot id: Q8SRT5
names: Subcellular Location Annotation
messages: Membrane

284813:ECU11 0050
gene id: 284813:ECU11_0050
uniprot id: Q8STA9
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU10 0180
gene id: 284813:ECU10_0180
uniprot id: Q8SR79
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

284813:ECU08 0765
gene id: 284813:ECU08_0765
uniprot id: Q8SRC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

284813:ECU06 0070
gene id: 284813:ECU06_0070
uniprot id: Q8SVF5
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU05 1610
gene id: 284813:ECU05_1610
uniprot id: Q8ST42
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU04 1080
gene id: 284813:ECU04_1080
uniprot id: Q8SVT0
names: Developmental Stage
names: Subcellular Location Annotation
messages: Expressed in late sporogonial stages.
messages: Membrane

284813:ECU02 1090
gene id: 284813:ECU02_1090
uniprot id: Q8SSE9
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU10 0120
gene id: 284813:ECU10_0120
uniprot id: Q8SR83
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC7 subfamily.
messages: Serine/threonine-protein kinase. Needed for the initiation of DNA synthesis during mitosis as well as for synaptonemal complex formation and commitment to recombination during meiosis (By similarity).

284813:ECU05 0140
gene id: 284813:ECU05_0140
uniprot id: Q8SVN2
names: Developmental Stage
names: Subcellular Location Annotation
messages: Expressed in late sporogonial stages.
messages: Membrane

284813:ECU02 1490
gene id: 284813:ECU02_1490
uniprot id: Q8SSD4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Mitochondrion
messages: Monomer.

284813:ECU04 0380
gene id: 284813:ECU04_0380
uniprot id: Q8SVW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

284813:ECU09 0720
gene id: 284813:ECU09_0720
uniprot id: Q8SQN7
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel (By similarity).
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity (By similarity).

284813:ECU08 0050
gene id: 284813:ECU08_0050
uniprot id: Q8STB3
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU04 0850
gene id: 284813:ECU04_0850
uniprot id: Q8SS42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

284813:ECU10 0960
gene id: 284813:ECU10_0960
uniprot id: Q8SUE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

284813:ECU09 1470
gene id: 284813:ECU09_1470
uniprot id: Q8STN7
names: Developmental Stage
messages: Expressed in late sporogonial stages.

284813:ECU08 1090
gene id: 284813:ECU08_1090
uniprot id: Q8SUP3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

284813:ECU10 0510
gene id: 284813:ECU10_0510
uniprot id: Q8SR61
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

284813:ECU08 0070
gene id: 284813:ECU08_0070
uniprot id: Q8SRG3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

284813:ECU04 1650
gene id: 284813:ECU04_1650
uniprot id: Q8SVP4
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU09 1730
gene id: 284813:ECU09_1730
uniprot id: Q8STL7
names: Similarity
messages: Belongs to the CDC73 family.

284813:ECU10 0840
gene id: 284813:ECU10_0840
uniprot id: Q8SUE8
names: Similarity
messages: Belongs to the Luc7 family.

284813:ECU11 0390
gene id: 284813:ECU11_0390
uniprot id: Q8SU74
names: Similarity
messages: Belongs to the SEC6 family.

284813:ECU10 0920
gene id: 284813:ECU10_0920
uniprot id: Q8SR37
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Heterodimer of a large and a small subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
messages: Under complex allosteric control mediated by deoxynucleoside triphosphates and ATP binding to separate specificity and activation sites on the large subunit. The type of nucleotide bound at the specificity site determines substrate preference. It seems probable that ATP makes the enzyme reduce CDP and UDP, dGTP favors ADP reduction and dTTP favors GDP reduction. Stimulated by ATP and inhibited by dATP binding to the activity site (By similarity).

284813:ECU02 0060
gene id: 284813:ECU02_0060
uniprot id: Q8SWH6
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU10 0950
gene id: 284813:ECU10_0950
uniprot id: Q8SUE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

284813:ECU01 0470
gene id: 284813:ECU01_0470
uniprot id: Q8SSM3
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU09 0920
gene id: 284813:ECU09_0920
uniprot id: Q8SQN1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

284813:ECU01 1000
gene id: 284813:ECU01_1000
uniprot id: Q8SSK4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

284813:ECU08 0290
gene id: 284813:ECU08_0290
uniprot id: Q8SRF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

284813:ECU03 0670
gene id: 284813:ECU03_0670
uniprot id: Q8SSA4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

284813:ECU11 1620i
gene id: 284813:ECU11_1620i
uniprot id: Q8SQS8
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: Component of the small ribosomal subunit.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU06 0020
gene id: 284813:ECU06_0020
uniprot id: Q8ST81
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU09 1880
gene id: 284813:ECU09_1880
uniprot id: Q8STL0
names: Developmental Stage
messages: Expressed in late sporogonial stages.

284813:ECU04 1440
gene id: 284813:ECU04_1440
uniprot id: Q8ST28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

284813:ECU03 0360
gene id: 284813:ECU03_0360
uniprot id: Q8SSB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

284813:ECU07 1120
gene id: 284813:ECU07_1120
uniprot id: Q8SUY5
names: Developmental Stage
messages: Expressed in late sporogonial stages.

284813:ECU11 0530
gene id: 284813:ECU11_0530
uniprot id: O96771
names: Developmental Stage
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Expressed in late sporogonial stages.
messages: Homodimer.

284813:ECU01 0330
gene id: 284813:ECU01_0330
uniprot id: Q8SWP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: nucleolus

284813:ECU03 0680
gene id: 284813:ECU03_0680
uniprot id: Q8SSA3
names: Similarity
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.

284813:ECU11 0220
gene id: 284813:ECU11_0220
uniprot id: Q8SQZ2
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU08 0020
gene id: 284813:ECU08_0020
uniprot id: Q8ST67
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU08 1400
gene id: 284813:ECU08_1400
uniprot id: Q8SUM6
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU01 0840
gene id: 284813:ECU01_0840
uniprot id: Q8SWL2
names: Developmental Stage
messages: Expressed in late sporogonial stages.

284813:ECU11 0930i
gene id: 284813:ECU11_0930i
uniprot id: Q8SQW4
names: Similarity
messages: Belongs to the eIF-2-alpha family.

284813:ECU02 1350
gene id: 284813:ECU02_1350
uniprot id: Q8SSD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

284813:ECU01 0400
gene id: 284813:ECU01_0400
uniprot id: Q8SWP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Membrane
messages: Probably involved in transport through the plasma membrane.

284813:ECU01 1310
gene id: 284813:ECU01_1310
uniprot id: Q8SWI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the frataxin family.
messages: Mitosome
messages: Monomer.
messages: Promotes the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways.

284813:ECU09 0630
gene id: 284813:ECU09_0630
uniprot id: Q8STU1
names: Function
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

284813:ECU10 1760
gene id: 284813:ECU10_1760
uniprot id: Q8SQZ8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

284813:ECU03 1190
gene id: 284813:ECU03_1190
uniprot id: Q8SS85
names: Developmental Stage
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Expressed in late sporogonial stages.
messages: Homodimer; disulfide-linked, upon oxidation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this typical 2-Cys peroxiredoxin, C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.

284813:ECU11 1290
gene id: 284813:ECU11_1290
uniprot id: Q8SQU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
messages: May play a role in the control of the eukaryotic cell cycle.
messages: Nucleus

284813:ECU05 0510
gene id: 284813:ECU05_0510
uniprot id: Q8SVL5
names: Developmental Stage
messages: Expressed in late sporogonial stages.

284813:ECU01 0090
gene id: 284813:ECU01_0090
uniprot id: Q8ST67
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU11 1930
gene id: 284813:ECU11_1930
uniprot id: Q8STZ8
names: Function
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.

284813:ECU08 1510
gene id: 284813:ECU08_1510
uniprot id: Q8SUL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

284813:ECU07 0960
gene id: 284813:ECU07_0960
uniprot id: Q8SRJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Nucleus

284813:ECU11 1450
gene id: 284813:ECU11_1450
uniprot id: Q8SQT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: nuclear pore complex

284813:ECU11 1610
gene id: 284813:ECU11_1610
uniprot id: Q8SQS9
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

284813:ECU04 1150
gene id: 284813:ECU04_1150
uniprot id: Q8SVS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

284813:ECU05 1100
gene id: 284813:ECU05_1100
uniprot id: Q8SVI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.

284813:ECU04 0900
gene id: 284813:ECU04_0900
uniprot id: Q8SS40
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

284813:ECU11 1090
gene id: 284813:ECU11_1090
uniprot id: Q8SU38
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERF4 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with ERF2.

284813:ECU04 1310
gene id: 284813:ECU04_1310
uniprot id: Q8SS18
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

284813:ECU07 1380
gene id: 284813:ECU07_1380
uniprot id: Q8SRH8
names: Function
names: Similarity
messages: Component of the 60S subunit of the ribosome.
messages: In the N-terminal section; belongs to the ubiquitin family.

284813:ECU01 0420
gene id: 284813:ECU01_0420
uniprot id: Q8SWP1
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWP12 family.
messages: Expressed in late sporogonial stages.
messages: Spore wall

284813:ECU06 0240
gene id: 284813:ECU06_0240
uniprot id: Q8SRT0
names: Developmental Stage
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Expressed in late sporogonial stages.
messages: Interacts with PTP1 and PTP3.
messages: Involved in formation of a polar tube through which the infectious agent is passed on to the host cell.
messages: Spore polar tube

284813:ECU10 0270
gene id: 284813:ECU10_0270
uniprot id: Q8SR73
names: Similarity
messages: Belongs to the RNase PH family.

284813:ECU09 0490
gene id: 284813:ECU09_0490
uniprot id: Q8STV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: nuclear pore complex

284813:ECU01 0670
gene id: 284813:ECU01_0670
uniprot id: Q8SWM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

284813:ECU05 0160
gene id: 284813:ECU05_0160
uniprot id: Q8SS08
names: Similarity
messages: Belongs to the amino acid/polyamine transporter 2 family.

284813:ECU08 1480
gene id: 284813:ECU08_1480
uniprot id: Q8SR98
names: Similarity
messages: Belongs to the protein kinase superfamily.

284813:ECU04 0980
gene id: 284813:ECU04_0980
uniprot id: Q8SS36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cytoplasm

284813:ECU01 0180
gene id: 284813:ECU01_0180
uniprot id: O62584
names: Similarity
messages: Belongs to the thymidylate synthase family.

284813:ECU07 0860
gene id: 284813:ECU07_0860
uniprot id: Q8SRJ4
names: Similarity
messages: Belongs to the cullin family.

284813:ECU05 0560
gene id: 284813:ECU05_0560
uniprot id: Q8SVL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

284813:ECU03 1270
gene id: 284813:ECU03_1270
uniprot id: Q8SS83
names: Similarity
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.

284813:ECU05 1340
gene id: 284813:ECU05_1340
uniprot id: Q8SRU7
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel (By similarity).
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity (By similarity).

284813:ECU11 0120
gene id: 284813:ECU11_0120
uniprot id: Q8ST42
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU03 1490
gene id: 284813:ECU03_1490
uniprot id: Q8SS76
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

284813:ECU08 1080
gene id: 284813:ECU08_1080
uniprot id: Q8SRB2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing.
messages: Associates with polysomes.
messages: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
messages: Cytoplasm
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284813:ECU01 1320
gene id: 284813:ECU01_1320
uniprot id: Q8SSJ0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

284813:ECU07 1850
gene id: 284813:ECU07_1850
uniprot id: Q8ST44
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU10 1090
gene id: 284813:ECU10_1090
uniprot id: Q8SUD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ING family.
messages: Nucleus

284813:ECU08 0900
gene id: 284813:ECU08_0900
uniprot id: Q8SRB6
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

284813:ECU06 1040
gene id: 284813:ECU06_1040
uniprot id: Q8SRP6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit. Active with Co(2+), Fe(2+), Mn(2+) and Zn(2+).
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

284813:ECU10 1640
gene id: 284813:ECU10_1640
uniprot id: Q8SR02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

284813:ECU02 0430
gene id: 284813:ECU02_0430
uniprot id: Q8SSH8
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

284813:ECU10 0810
gene id: 284813:ECU10_0810
uniprot id: Q8SUE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex, which consists of at least NDC80 and NUF2.
messages: Nucleus
messages: kinetochore

284813:ECU10 1070
gene id: 284813:ECU10_1070
uniprot id: Q8SUD4
names: Developmental Stage
messages: Expressed in late sporogonial stages.

284813:ECU02 0730
gene id: 284813:ECU02_0730
uniprot id: Q8SSG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

284813:ECU09 1680
gene id: 284813:ECU09_1680
uniprot id: Q8SQK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

284813:ECU04 0600
gene id: 284813:ECU04_0600
uniprot id: Q8SS55
names: Similarity
messages: Belongs to the peptidase M24B family.

284813:ECU10 0620
gene id: 284813:ECU10_0620
uniprot id: Q8SR54
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Active in protein import into the nucleus.
messages: Belongs to the importin beta family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Nucleus

284813:ECU07 0320
gene id: 284813:ECU07_0320
uniprot id: Q8SRL8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

284813:ECU08 0230
gene id: 284813:ECU08_0230
uniprot id: Q8SRF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
messages: May play a role in the control of the eukaryotic cell cycle.
messages: Nucleus

284813:ECU09 1790
gene id: 284813:ECU09_1790
uniprot id: Q8SQK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

284813:ECU09 1390
gene id: 284813:ECU09_1390
uniprot id: Q8STP2
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Component of the SWR1 chromatin remodeling complex, the INO80 chromatin remodeling complex, and of the R2TP complex.
messages: DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
messages: Expressed in late sporogonial stages.
messages: Nucleus

284813:ECU07 1350
gene id: 284813:ECU07_1350
uniprot id: Q8SRH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.

284813:ECU11 1030
gene id: 284813:ECU11_1030
uniprot id: Q8SQV9
names: Similarity
messages: Belongs to the AAA ATPase family.

284813:ECU02 1470
gene id: 284813:ECU02_1470
uniprot id: Q8SW90
names: Developmental Stage
names: Subcellular Location Annotation
messages: Expressed in late sporogonial stages.
messages: Membrane

284813:ECU04 1030
gene id: 284813:ECU04_1030
uniprot id: Q8SVT3
names: Subcellular Location Annotation
messages: Nucleus

284813:ECU05 0970
gene id: 284813:ECU05_0970
uniprot id: Q8SVJ2
names: Function
names: Similarity
messages: Belongs to the NARF family.
messages: Component of the cytosolic Fe/S protein assembly machinery. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).

284813:ECU05 0650
gene id: 284813:ECU05_0650
uniprot id: Q8SRY1
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPI family.
messages: Expressed in late sporogonial stages.
messages: Homodimer.
messages: In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.
messages: cytosol

284813:ECU06 0790
gene id: 284813:ECU06_0790
uniprot id: Q8SRQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer.

284813:ECU03 0020
gene id: 284813:ECU03_0020
uniprot id: Q8SW84
names: Similarity
messages: Belongs to the UPF0328 family.

284813:ECU07 1410
gene id: 284813:ECU07_1410
uniprot id: Q8SRH7
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

284813:ECU06 1030
gene id: 284813:ECU06_1030
uniprot id: Q8SRP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: nucleolus

284813:ECU02 0080
gene id: 284813:ECU02_0080
uniprot id: Q8SWH4
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU03 0620
gene id: 284813:ECU03_0620
uniprot id: Q8SSA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.
messages: Nucleus
messages: Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles (By similarity).

284813:ECU07 1880
gene id: 284813:ECU07_1880
uniprot id: Q8STD6
names: Similarity
messages: Belongs to the UPF0329 family.

284813:ECU07 1310
gene id: 284813:ECU07_1310
uniprot id: Q8SUX2
names: Similarity
messages: Belongs to the FAM72 family.

284813:ECU11 0660
gene id: 284813:ECU11_0660
uniprot id: Q8SQX8
names: Similarity
messages: Belongs to the PPP phosphatase family.

284813:ECU01 0610
gene id: 284813:ECU01_0610
uniprot id: Q8SSL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

284813:ECU11 0590
gene id: 284813:ECU11_0590
uniprot id: Q8SQY2
names: Similarity
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.

284813:ECU02 0510
gene id: 284813:ECU02_0510
uniprot id: Q8SSH4
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Involved in the regulation of the onset of mitosis. Involved in a pathway that coordinates cell proliferation and differentiation. Implicated in spindle pole body (SPD) duplication. Dual specificity kinase that can phosphorylate serine, threonine and tyrosine residues (By similarity).

284813:ECU05 0440
gene id: 284813:ECU05_0440
uniprot id: Q8SRZ0
names: Cofactor
names: Developmental Stage
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Expressed in late sporogonial stages.

284813:ECU03 0760
gene id: 284813:ECU03_0760
uniprot id: Q8SW46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NCBP2 family.
messages: Nucleus

284813:ECU08 1790
gene id: 284813:ECU08_1790
uniprot id: Q8SR90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
messages: May play a role in the control of the eukaryotic cell cycle.
messages: Nucleus

284813:ECU09 1350
gene id: 284813:ECU09_1350
uniprot id: Q8SQL9
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

284813:ECU07 1005
gene id: 284813:ECU07_1005
uniprot id: Q8SRJ2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

284813:ECU07 1820
gene id: 284813:ECU07_1820
uniprot id: Q8ST62
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Component of the large ribosomal subunit.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.

284813:ECU07 1640
gene id: 284813:ECU07_1640
uniprot id: Q8SRH0
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a regulatory subunit of the 26S proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH (By similarity).
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Expressed in late sporogonial stages.
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel (By similarity).

284813:ECU03 1080
gene id: 284813:ECU03_1080
uniprot id: Q8SS91
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Mitochondrion
messages: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm