284592:DEHA2F09306g
gene id: 284592:DEHA2F09306g
uniprot id: Q6BM06
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

284592:DEHA2G09614g
gene id: 284592:DEHA2G09614g
uniprot id: Q6BIK7
names: Similarity
messages: Belongs to the SIN1 family.

284592:DEHA2C17446g
gene id: 284592:DEHA2C17446g
uniprot id: Q6BTL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

284592:DEHA2F14740g
gene id: 284592:DEHA2F14740g
uniprot id: Q6BLB9
names: Similarity
messages: Belongs to the AAA ATPase family.

284592:DEHA2F09152g
gene id: 284592:DEHA2F09152g
uniprot id: Q6BM12
names: Similarity
messages: Belongs to the glycosyltransferase 34 family.

284592:DEHA2D08976g
gene id: 284592:DEHA2D08976g
uniprot id: Q6BSG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDE2 family.
messages: Nucleus

284592:DEHA2D15114g
gene id: 284592:DEHA2D15114g
uniprot id: Q6BRN1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

284592:DEHA2G01496g
gene id: 284592:DEHA2G01496g
uniprot id: B5RV15
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

284592:DEHA2D10384g
gene id: 284592:DEHA2D10384g
uniprot id: Q6BSA3
names: Similarity
messages: Belongs to the Tango6 family.

284592:DEHA2A14696g
gene id: 284592:DEHA2A14696g
uniprot id: Q6BXV6
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2A04642g
gene id: 284592:DEHA2A04642g
uniprot id: Q6BZ46
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G10516g
gene id: 284592:DEHA2G10516g
uniprot id: B5RUP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2D08030g
gene id: 284592:DEHA2D08030g
uniprot id: Q6BSL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VTS1 family.
messages: Monomer. Binds to RNA.
messages: P-body
messages: RNA-binding protein involved in post-transcriptional regulation through transcript degradation.
messages: cytosol

284592:DEHA2F16984g
gene id: 284592:DEHA2F16984g
uniprot id: Q6BL22
names: Similarity
messages: Belongs to the WrbA family.

284592:DEHA2D17886g
gene id: 284592:DEHA2D17886g
uniprot id: Q6BRA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG11 family.
messages: Homodimer.
messages: Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion (By similarity).
messages: Preautophagosomal structure membrane
messages: Vacuole membrane

284592:DEHA2E17600g
gene id: 284592:DEHA2E17600g
uniprot id: Q6BP05
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

284592:DEHA2F10494g
gene id: 284592:DEHA2F10494g
uniprot id: Q6BLV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAC-beta family.
messages: Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD1 may act as a transcription factor that exert a negative effect on the expression of several genes that are transcribed by RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Part of the nascent polypeptide-associated complex (NAC), consisting of EGD2 and EGD1. NAC associates with ribosomes via EGD1 (By similarity).

284592:DEHA2G05962g
gene id: 284592:DEHA2G05962g
uniprot id: Q6BJ15
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

284592:DEHA2F23188g
gene id: 284592:DEHA2F23188g
uniprot id: Q6BKC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.
messages: Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.
messages: Component of the SWR1 chromatin-remodeling complex.
messages: Nucleus

284592:DEHA2B05060g
gene id: 284592:DEHA2B05060g
uniprot id: Q6BX87
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284592:DEHA2F23540g
gene id: 284592:DEHA2F23540g
uniprot id: Q6BKA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

284592:DEHA2C07722g
gene id: 284592:DEHA2C07722g
uniprot id: Q6BUV3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284592:DEHA2E08932g
gene id: 284592:DEHA2E08932g
uniprot id: Q6BQ24
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

284592:DEHA2C02266g
gene id: 284592:DEHA2C02266g
uniprot id: Q6BVJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

284592:DEHA2G20526g
gene id: 284592:DEHA2G20526g
uniprot id: Q6BH86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: Membrane

284592:DEHA2F08448g
gene id: 284592:DEHA2F08448g
uniprot id: B5RUC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2E06952g
gene id: 284592:DEHA2E06952g
uniprot id: Q6BQA8
names: Similarity
messages: Belongs to the pirin family.

284592:DEHA2F11924g
gene id: 284592:DEHA2F11924g
uniprot id: Q6BLN9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.
messages: cytosol

284592:DEHA2F09020g
gene id: 284592:DEHA2F09020g
uniprot id: Q6BM17
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

284592:DEHA2B04180g
gene id: 284592:DEHA2B04180g
uniprot id: Q6BXC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

284592:DEHA2B04400g
gene id: 284592:DEHA2B04400g
uniprot id: Q6BXB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC24 family.
messages: Component of the NDC80 complex, which consists of NDC80, NUF2, SPC24 and SPC25.
messages: Nucleus
messages: kinetochore

284592:DEHA2G24662g
gene id: 284592:DEHA2G24662g
uniprot id: Q6BGQ7
names: Similarity
messages: Belongs to the TIP41 family.

284592:DEHA2F16566g
gene id: 284592:DEHA2F16566g
uniprot id: Q6BL42
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

284592:DEHA2F10362g
gene id: 284592:DEHA2F10362g
uniprot id: Q6BLV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
messages: Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro. Required for respiration and the maintenance of the mitochondrial compartment.
messages: Homodimer.
messages: Mitochondrion matrix

284592:DEHA2F26312g
gene id: 284592:DEHA2F26312g
uniprot id: Q6BJY7
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2A09350g
gene id: 284592:DEHA2A09350g
uniprot id: Q6BYI3
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

284592:DEHA2G12474g
gene id: 284592:DEHA2G12474g
uniprot id: Q6BI95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and regulates mRNA decay through translation termination-coupled poly(A) shortening, probably mediated by PAN (By similarity).
messages: Cytoplasm
messages: Nucleus

284592:DEHA2B14454g
gene id: 284592:DEHA2B14454g
uniprot id: Q6BW45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

284592:DEHA2A09878g
gene id: 284592:DEHA2A09878g
uniprot id: Q6BYF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Component of the SRB8-11 complex, a regulatory module of the Mediator complex.
messages: Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity).
messages: Nucleus

284592:DEHA2C00792g
gene id: 284592:DEHA2C00792g
uniprot id: Q6BVQ4
names: Similarity
messages: Belongs to the arginase family.

284592:DEHA2F00924g
gene id: 284592:DEHA2F00924g
uniprot id: Q6BN19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM18/AIM46 family.
messages: Mitochondrion

284592:DEHA2B14432g
gene id: 284592:DEHA2B14432g
uniprot id: Q6BW46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTC6 family.
messages: May be involved in telomere capping.
messages: Membrane

284592:DEHA2D06204g
gene id: 284592:DEHA2D06204g
uniprot id: Q6BSU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm.
messages: nucleolus

284592:DEHA2G04884g
gene id: 284592:DEHA2G04884g
uniprot id: Q6BJ63
names: Similarity
messages: Belongs to the MIX23 family.

284592:DEHA2B13706g
gene id: 284592:DEHA2B13706g
uniprot id: Q6BW77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCC1 family.
messages: Membrane

284592:DEHA2A12386g
gene id: 284592:DEHA2A12386g
uniprot id: Q6BY50
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284592:DEHA2F19448g
gene id: 284592:DEHA2F19448g
uniprot id: B5RUJ4
names: Similarity
messages: Belongs to the IWR1/SLC7A6OS family.

284592:DEHA2C02904g
gene id: 284592:DEHA2C02904g
uniprot id: Q6BVG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

284592:DEHA2C04048g
gene id: 284592:DEHA2C04048g
uniprot id: Q6BVA9
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

284592:DEHA2C02530g
gene id: 284592:DEHA2C02530g
uniprot id: B5RT63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2E05808g
gene id: 284592:DEHA2E05808g
uniprot id: Q6BQE5
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

284592:DEHA2A08734g
gene id: 284592:DEHA2A08734g
uniprot id: Q6BYL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

284592:DEHA2B14520g
gene id: 284592:DEHA2B14520g
uniprot id: Q6BW42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Endoplasmic reticulum membrane

284592:DEHA2F21692g
gene id: 284592:DEHA2F21692g
uniprot id: W0TYU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC3 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).

284592:DEHA2E16808g
gene id: 284592:DEHA2E16808g
uniprot id: Q6BP36
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G19998g
gene id: 284592:DEHA2G19998g
uniprot id: Q6BHA8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Cytoplasm
messages: Nucleus
messages: This protein is considered an atypical serine/threonine kinase, because it lacks the conventional structural elements necessary for the substrate recognition as well as a lysine residue that in all other serine/threonine kinases participates in the catalytic event (By similarity). BUD32 has protein kinase activity in vitro, but in the context of the EKC/KEOPS complex, the catalytic subunit KAE1 switches the activity of BUD32 from kinase into ATPase (By similarity).
messages: telomere

284592:DEHA2A08866g
gene id: 284592:DEHA2A08866g
uniprot id: Q6BYK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

284592:DEHA2B13354g
gene id: 284592:DEHA2B13354g
uniprot id: Q6BW93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRC22 family.
messages: Endoplasmic reticulum membrane
messages: Is probably involved in a pathway contributing to genomic integrity.

284592:DEHA2C05214g
gene id: 284592:DEHA2C05214g
uniprot id: Q6BV56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2C16786g
gene id: 284592:DEHA2C16786g
uniprot id: Q6BTQ1
names: Subcellular Location Annotation
messages: nucleolus

284592:DEHA2E18480g
gene id: 284592:DEHA2E18480g
uniprot id: Q6BNW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

284592:DEHA2E21098g
gene id: 284592:DEHA2E21098g
uniprot id: Q6BNJ9
names: Similarity
messages: Belongs to the RCAN family.

284592:DEHA2B06182g
gene id: 284592:DEHA2B06182g
uniprot id: Q6BX40
names: Similarity
messages: Belongs to the Tom22 family.

284592:DEHA2A00792g
gene id: 284592:DEHA2A00792g
uniprot id: Q6BZJ7
names: Similarity
messages: Belongs to the BMT family.

284592:DEHA2G15158g
gene id: 284592:DEHA2G15158g
uniprot id: Q6BHX1
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2A04488g
gene id: 284592:DEHA2A04488g
uniprot id: Q6BZ52
names: Function
names: Similarity
messages: Belongs to the HisA/HisF family.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain.
messages: In the C-terminal section; belongs to the HisA/HisF family.

284592:DEHA2E14080g
gene id: 284592:DEHA2E14080g
uniprot id: Q6BPF2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

284592:DEHA2F23606g
gene id: 284592:DEHA2F23606g
uniprot id: Q6BKA2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

284592:DEHA2D11374g
gene id: 284592:DEHA2D11374g
uniprot id: Q6BS60
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity).
messages: Forms a stable heterodimer with SPT16. The SPT16-POB3 dimer weakly associates with multiple molecules of NHP6 to form the FACT complex (By similarity).
messages: In contrast to the orthologous protein in animals and plants, this protein does not contain a HMG box DNA-binding domain. This function may instead be provided by the HMG box of the associated NHP6 protein in the FACT complex of fungi.
messages: Nucleus

284592:DEHA2D09526g
gene id: 284592:DEHA2D09526g
uniprot id: Q6BSE1
names: Similarity
messages: Belongs to the TSR2 family.

284592:DEHA2G17204g
gene id: 284592:DEHA2G17204g
uniprot id: B5RUU6
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

284592:DEHA2E01738g
gene id: 284592:DEHA2E01738g
uniprot id: Q6BQW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.
messages: Homodimer.

284592:DEHA2G16126g
gene id: 284592:DEHA2G16126g
uniprot id: Q6BHS5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cation homeostasis and in the regulation of the cation stress signaling cascades.
messages: Nucleus

284592:DEHA2G05214g
gene id: 284592:DEHA2G05214g
uniprot id: Q6BJ48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI) (By similarity).
messages: Interacts with EME1.
messages: Nucleus

284592:DEHA2G14916g
gene id: 284592:DEHA2G14916g
uniprot id: Q6BHY3
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F19162g
gene id: 284592:DEHA2F19162g
uniprot id: Q6BKU3
names: Similarity
messages: Belongs to the SNAP-25 family.

284592:DEHA2D13904g
gene id: 284592:DEHA2D13904g
uniprot id: Q6BRT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

284592:DEHA2D04290g
gene id: 284592:DEHA2D04290g
uniprot id: Q6BT17
names: Similarity
messages: Belongs to the BMT family.

284592:DEHA2D11902g
gene id: 284592:DEHA2D11902g
uniprot id: B5RTH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

284592:DEHA2E01606g
gene id: 284592:DEHA2E01606g
uniprot id: Q6BQX1
names: Similarity
messages: Belongs to the CCDC25 family.

284592:DEHA2G08096g
gene id: 284592:DEHA2G08096g
uniprot id: Q6BIS1
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: The active site is a redox-active disulfide bond.

284592:DEHA2F12188g
gene id: 284592:DEHA2F12188g
uniprot id: Q6BLM7
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F16588g
gene id: 284592:DEHA2F16588g
uniprot id: Q6BL40
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G06446g
gene id: 284592:DEHA2G06446g
uniprot id: Q6BIZ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

284592:DEHA2G18942g
gene id: 284592:DEHA2G18942g
uniprot id: Q6BHF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG23 family.
messages: Cytoplasm
messages: Membrane
messages: Required for cytoplasm to vacuole transport (Cvt) vesicle formation and efficient autophagy. Plays a role in ATG protein retrieval from the pre-autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9. Also plays a role in regulation of filamentous growth (By similarity).

284592:DEHA2D14476g
gene id: 284592:DEHA2D14476g
uniprot id: Q6BRR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat SEC31 family.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
messages: Endoplasmic reticulum membrane
messages: The COPII coat is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex, and the protein SAR1. SEC13 and SEC31 make a 2:2 tetramer that forms the edge element of the COPII outer coat. The tetramer self-assembles in multiple copies to form the complete polyhedral cage. Interacts (via WD 8) with SEC13 (By similarity).

284592:DEHA2D04026g
gene id: 284592:DEHA2D04026g
uniprot id: B5RTR0
names: Subcellular Location Annotation
messages: Cytoplasm

284592:DEHA2G23650g
gene id: 284592:DEHA2G23650g
uniprot id: Q6BGV3
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

284592:DEHA2G00682g
gene id: 284592:DEHA2G00682g
uniprot id: Q6BJQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family. UbiD-like/FDC subfamily.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites.
messages: Cytoplasm
messages: Homodimer. May form higher order oligomers.

284592:DEHA2E12826g
gene id: 284592:DEHA2E12826g
uniprot id: Q6BPK6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

284592:DEHA2E08888g
gene id: 284592:DEHA2E08888g
uniprot id: B5RTX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

284592:DEHA2A00704g
gene id: 284592:DEHA2A00704g
uniprot id: Q6BZK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

284592:DEHA2F04048g
gene id: 284592:DEHA2F04048g
uniprot id: Q6BMM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 15 family.
messages: Nucleus

284592:DEHA2B02178g
gene id: 284592:DEHA2B02178g
uniprot id: Q6BXK7
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

284592:DEHA2G13200g
gene id: 284592:DEHA2G13200g
uniprot id: Q6BI60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
messages: May form heterododecamers with RVB2. Component of the SWR1 chromatin remodeling complex, the INO80 chromatin remodeling complex, and of the R2TP complex (By similarity).
messages: Nucleus

284592:DEHA2G04356g
gene id: 284592:DEHA2G04356g
uniprot id: Q6BJ86
names: Similarity
messages: Belongs to the SGT family.

284592:DEHA2A01034g
gene id: 284592:DEHA2A01034g
uniprot id: Q6BZI5
names: Similarity
messages: Belongs to the RRN3 family.

284592:DEHA2D04620g
gene id: 284592:DEHA2D04620g
uniprot id: Q6BT03
names: Similarity
messages: Belongs to the patched family.

284592:DEHA2A04796g
gene id: 284592:DEHA2A04796g
uniprot id: Q6BZ39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Involved in vacuolar transport and vacuole pH homeostasis. Also required for cytokinesis (By similarity).
messages: Vacuole membrane

284592:DEHA2G22572g
gene id: 284592:DEHA2G22572g
uniprot id: Q6BGZ3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

284592:DEHA2E05742g
gene id: 284592:DEHA2E05742g
uniprot id: Q6BQE8
names: Similarity
messages: Belongs to the NPR2 family.

284592:DEHA2D02816g
gene id: 284592:DEHA2D02816g
uniprot id: Q6BT81
names: Similarity
messages: Belongs to the peptidase S8 family.

284592:DEHA2D07062g
gene id: 284592:DEHA2D07062g
uniprot id: Q6BSQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic component of the histone acetylase B (HAT-B) complex. Acetylates 'Lys-12' of histone H4 which is required for telomeric silencing. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.
messages: Component of the HAT-B complex composed of at least HAT1 and HAT2. The HAT-B complex binds to histone H4 tail.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2E16082g
gene id: 284592:DEHA2E16082g
uniprot id: Q6BP68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

284592:DEHA2G11858g
gene id: 284592:DEHA2G11858g
uniprot id: Q6BIC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CGR1 family.
messages: Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.
messages: nucleolus

284592:DEHA2G03894g
gene id: 284592:DEHA2G03894g
uniprot id: Q6BJA6
names: Similarity
messages: Belongs to the RRP7 family.

284592:DEHA2F06666g
gene id: 284592:DEHA2F06666g
uniprot id: Q6BMC2
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

284592:DEHA2A12870g
gene id: 284592:DEHA2A12870g
uniprot id: Q6BY31
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.

284592:DEHA2C08206g
gene id: 284592:DEHA2C08206g
uniprot id: Q6BUT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NST1 family.
messages: Cytoplasm
messages: May act as a negative regulator of salt tolerance.

284592:DEHA2D04114g
gene id: 284592:DEHA2D04114g
uniprot id: Q6BT24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family.
messages: May be involved in vacuolar sorting and osmoregulation.
messages: Membrane
messages: Vacuole membrane

284592:DEHA2G19228g
gene id: 284592:DEHA2G19228g
uniprot id: Q6BHE6
names: Similarity
messages: Belongs to the SAPS family.

284592:DEHA2C00264g
gene id: 284592:DEHA2C00264g
uniprot id: Q6BVS5
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2B05412g
gene id: 284592:DEHA2B05412g
uniprot id: Q6BX73
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

284592:DEHA2B16698g
gene id: 284592:DEHA2B16698g
uniprot id: Q6BVU2
names: Subcellular Location Annotation
messages: telomere

284592:DEHA2E17644g
gene id: 284592:DEHA2E17644g
uniprot id: Q6BP03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat TRM82 family.
messages: Forms a heterodimer with the catalytic subunit TRM8.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

284592:DEHA2E12078g
gene id: 284592:DEHA2E12078g
uniprot id: Q6BPN8
names: Function
names: Similarity
messages: Belongs to the CCM1 family.
messages: RNA-binding protein involved in the specific removal of group I introns in mitochondrial encoded transcripts. Maintains the stability of the small subunit mitochondrial 15S rRNA and thus the expression of the mitochondrial genome.

284592:DEHA2F21868g
gene id: 284592:DEHA2F21868g
uniprot id: Q6BKH9
names: Function
names: Similarity
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.

284592:DEHA2E18634g
gene id: 284592:DEHA2E18634g
uniprot id: Q6BNV8
names: Similarity
messages: Belongs to the cytochrome P450 family.

284592:DEHA2G12606g
gene id: 284592:DEHA2G12606g
uniprot id: B5RUR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

284592:DEHA2F16632g
gene id: 284592:DEHA2F16632g
uniprot id: Q6BL38
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284592:DEHA2G23782g
gene id: 284592:DEHA2G23782g
uniprot id: Q6BGU8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity).
messages: Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284592:DEHA2E18062g
gene id: 284592:DEHA2E18062g
uniprot id: Q6BNY2
names: Similarity
messages: Belongs to the cyclin family.

284592:DEHA2F20702g
gene id: 284592:DEHA2F20702g
uniprot id: Q6BKM3
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E18986g
gene id: 284592:DEHA2E18986g
uniprot id: Q6BNU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

284592:DEHA2A13530g
gene id: 284592:DEHA2A13530g
uniprot id: B5RSV7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

284592:DEHA2B00814g
gene id: 284592:DEHA2B00814g
uniprot id: Q6BXR6
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2A14124g
gene id: 284592:DEHA2A14124g
uniprot id: Q6BXX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat RTC1 family.
messages: May be involved in a process influencing telomere capping.
messages: Vacuole

284592:DEHA2C13068g
gene id: 284592:DEHA2C13068g
uniprot id: Q6BU75
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

284592:DEHA2E20130g
gene id: 284592:DEHA2E20130g
uniprot id: Q6BNP0
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.
messages: Responsible for the reduction of the keto group on the C-3 of sterols.

284592:DEHA2G14146g
gene id: 284592:DEHA2G14146g
uniprot id: Q6BI16
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2F06490g
gene id: 284592:DEHA2F06490g
uniprot id: Q6BMD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLT11 family.
messages: Involved in pre-mRNA splicing. Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome. Binds to RNA (By similarity).
messages: Nucleus

284592:DEHA2B10582g
gene id: 284592:DEHA2B10582g
uniprot id: Q6BWK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DASH complex DAM1 family.
messages: Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
messages: Nucleus
messages: The DASH complex oligomerizes to form rings that encircle the microtubules.
messages: kinetochore
messages: spindle

284592:DEHA2A08822g
gene id: 284592:DEHA2A08822g
uniprot id: B5RST2
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G09636g
gene id: 284592:DEHA2G09636g
uniprot id: Q6BIK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REXO4 family.
messages: Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs (By similarity).
messages: Nucleus

284592:DEHA2F23452g
gene id: 284592:DEHA2F23452g
uniprot id: B5RUM4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

284592:DEHA2F15290g
gene id: 284592:DEHA2F15290g
uniprot id: Q6BL96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.

284592:DEHA2G15620g
gene id: 284592:DEHA2G15620g
uniprot id: Q6BHU9
names: Similarity
messages: Belongs to the RNase PH family.

284592:DEHA2D13178g
gene id: 284592:DEHA2D13178g
uniprot id: Q6BRX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase inhibitor family.
messages: Forms a one-to-one complex with ATPase to inhibit the enzyme activity completely.
messages: Mitochondrion

284592:DEHA2D18062g
gene id: 284592:DEHA2D18062g
uniprot id: Q6BR98
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

284592:DEHA2D13156g
gene id: 284592:DEHA2D13156g
uniprot id: Q6BRX4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS18 family.

284592:DEHA2G05060g
gene id: 284592:DEHA2G05060g
uniprot id: Q6BJ55
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

284592:DEHA2G02618g
gene id: 284592:DEHA2G02618g
uniprot id: Q6BJG4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Cytoplasm

284592:DEHA2D04136g
gene id: 284592:DEHA2D04136g
uniprot id: Q6BT23
names: Subcellular Location Annotation
messages: Mitochondrion

284592:DEHA2F18700g
gene id: 284592:DEHA2F18700g
uniprot id: Q6BKW3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: cytoskeleton

284592:DEHA2A02200g
gene id: 284592:DEHA2A02200g
uniprot id: Q6BZD5
names: Similarity
messages: Belongs to the DNA polymerase type-B-like family.

284592:DEHA2G09856g
gene id: 284592:DEHA2G09856g
uniprot id: Q6BIJ6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.

284592:DEHA2C06182g
gene id: 284592:DEHA2C06182g
uniprot id: Q6BV12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

284592:DEHA2B00484g
gene id: 284592:DEHA2B00484g
uniprot id: Q6BXT1
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

284592:DEHA2C10516g
gene id: 284592:DEHA2C10516g
uniprot id: Q6BUH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

284592:DEHA2C09988g
gene id: 284592:DEHA2C09988g
uniprot id: Q6BUK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cell membrane
messages: coated pit

284592:DEHA2C14564g
gene id: 284592:DEHA2C14564g
uniprot id: Q6BU03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.
messages: Nucleus

284592:DEHA2D01452g
gene id: 284592:DEHA2D01452g
uniprot id: Q6BTD9
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G07282g
gene id: 284592:DEHA2G07282g
uniprot id: B5RV49
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

284592:DEHA2C03806g
gene id: 284592:DEHA2C03806g
uniprot id: Q6BVC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHO1 family.
messages: Cell membrane
messages: Forms homooligomers.
messages: Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.

284592:DEHA2C05544g
gene id: 284592:DEHA2C05544g
uniprot id: Q6BV41
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D05082g
gene id: 284592:DEHA2D05082g
uniprot id: Q6BSY3
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2A13244g
gene id: 284592:DEHA2A13244g
uniprot id: Q6BY14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

284592:DEHA2F26290g
gene id: 284592:DEHA2F26290g
uniprot id: Q6BJY8
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

284592:DEHA2A03652g
gene id: 284592:DEHA2A03652g
uniprot id: Q6BZ68
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Mitochondrion
messages: Monomer.

284592:DEHA2G21340g
gene id: 284592:DEHA2G21340g
uniprot id: Q6BH51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

284592:DEHA2F20526g
gene id: 284592:DEHA2F20526g
uniprot id: Q6BKN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX23 family.
messages: Mitochondrion intermembrane space
messages: Required for the assembly of cytochrome c oxidase.

284592:DEHA2E02464g
gene id: 284592:DEHA2E02464g
uniprot id: Q6BQT1
names: Similarity
messages: Belongs to the peptidase M16 family.

284592:DEHA2C16148g
gene id: 284592:DEHA2C16148g
uniprot id: Q6BTT0
names: Similarity
messages: Belongs to the COG4 family.

284592:DEHA2C04664g
gene id: 284592:DEHA2C04664g
uniprot id: Q6BV80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

284592:DEHA2F22990g
gene id: 284592:DEHA2F22990g
uniprot id: Q6BKC9
names: Similarity
messages: Belongs to the RMD1/sif2 family.

284592:DEHA2C04290g
gene id: 284592:DEHA2C04290g
uniprot id: Q6BV98
names: Similarity
messages: Belongs to the protein kinase superfamily.

284592:DEHA2E19096g
gene id: 284592:DEHA2E19096g
uniprot id: Q6BNT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MATALPHA1 family.
messages: Nucleus

284592:DEHA2F21934g
gene id: 284592:DEHA2F21934g
uniprot id: Q6BKH5
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

284592:DEHA2C02134g
gene id: 284592:DEHA2C02134g
uniprot id: Q6BVJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

284592:DEHA2G03542g
gene id: 284592:DEHA2G03542g
uniprot id: B5RV27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

284592:DEHA2D03674g
gene id: 284592:DEHA2D03674g
uniprot id: Q6BT43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.
messages: nucleolus

284592:DEHA2E06160g
gene id: 284592:DEHA2E06160g
uniprot id: Q6BQC9
names: Similarity
messages: Belongs to the TAF11 family.

284592:DEHA2G20262g
gene id: 284592:DEHA2G20262g
uniprot id: B5RUW5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284592:DEHA2F13948g
gene id: 284592:DEHA2F13948g
uniprot id: Q6BLF1
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.

284592:DEHA2A02508g
gene id: 284592:DEHA2A02508g
uniprot id: Q6BZC1
names: Subcellular Location Annotation
messages: Cytoplasm

284592:DEHA2F01210g
gene id: 284592:DEHA2F01210g
uniprot id: Q6BN05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGM101 family.
messages: Performs an essential function in the repair of oxidatively damaged mtDNA that is required for the maintenance of the mitochondrial genome. Binds to DNA (By similarity).
messages: mitochondrion nucleoid

284592:DEHA2E04774g
gene id: 284592:DEHA2E04774g
uniprot id: Q6BQJ3
names: Similarity
messages: Belongs to the lysophospholipase family.

284592:DEHA2D10912g
gene id: 284592:DEHA2D10912g
uniprot id: Q6BS82
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

284592:DEHA2G15840g
gene id: 284592:DEHA2G15840g
uniprot id: Q6BHU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DASH complex SPC19 family.
messages: Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
messages: Nucleus
messages: The DASH complex oligomerizes to form rings that encircle the microtubules.
messages: kinetochore
messages: spindle

284592:DEHA2C01012g
gene id: 284592:DEHA2C01012g
uniprot id: Q6BVP6
names: Similarity
messages: Belongs to the SurE nucleotidase family.

284592:DEHA2E18568g
gene id: 284592:DEHA2E18568g
uniprot id: Q6BNW1
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

284592:DEHA2F02530g
gene id: 284592:DEHA2F02530g
uniprot id: Q6BMU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2), composed of at least SUS1, SAC3, THP1, SEM1, and CDC31. TREX-2 contains 2 SUS1 chains. The TREX-2 complex interacts with the nucleoporin NUP1. Component of the 1.8 MDa SAGA transcription coactivator-HAT complex. SAGA is built of 5 distinct domains with specialized functions. Within the SAGA complex, SUS1, SGF11, SGF73 and UBP8 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with THP1, SAC3, SGF11, and with the RNA polymerase II.
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies (By similarity).
messages: P-body
messages: nucleoplasm

284592:DEHA2E10516g
gene id: 284592:DEHA2E10516g
uniprot id: Q6BPV6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

284592:DEHA2D03982g
gene id: 284592:DEHA2D03982g
uniprot id: Q6BT30
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

284592:DEHA2B14344g
gene id: 284592:DEHA2B14344g
uniprot id: Q6BW51
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

284592:DEHA2C09130g
gene id: 284592:DEHA2C09130g
uniprot id: B5RT93
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2B05544g
gene id: 284592:DEHA2B05544g
uniprot id: Q6BX68
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

284592:DEHA2F20064g
gene id: 284592:DEHA2F20064g
uniprot id: Q6BKQ3
names: Similarity
messages: Belongs to the CWC22 family.

284592:DEHA2A07678g
gene id: 284592:DEHA2A07678g
uniprot id: Q6BYQ8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

284592:DEHA2F08756g
gene id: 284592:DEHA2F08756g
uniprot id: Q6BM28
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

284592:DEHA2E23848g
gene id: 284592:DEHA2E23848g
uniprot id: Q6BN83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

284592:DEHA2F21824g
gene id: 284592:DEHA2F21824g
uniprot id: Q6BKI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284592:DEHA2A11242g
gene id: 284592:DEHA2A11242g
uniprot id: Q6BY98
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

284592:DEHA2E23342g
gene id: 284592:DEHA2E23342g
uniprot id: Q6BNA7
names: Similarity
messages: Belongs to the amidase family.

284592:DEHA2F07722g
gene id: 284592:DEHA2F07722g
uniprot id: Q6BM75
names: Similarity
messages: Belongs to the histidine acid phosphatase family.

284592:DEHA2B07194g
gene id: 284592:DEHA2B07194g
uniprot id: Q6BWZ8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

284592:DEHA2D14872g
gene id: 284592:DEHA2D14872g
uniprot id: Q6BRP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 22 family.
messages: Nucleus

284592:DEHA2C07942g
gene id: 284592:DEHA2C07942g
uniprot id: Q6BUU4
names: Similarity
messages: Belongs to the CBF/MAK21 family.

284592:DEHA2E03652g
gene id: 284592:DEHA2E03652g
uniprot id: Q6BQN7
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

284592:DEHA2G24178g
gene id: 284592:DEHA2G24178g
uniprot id: Q6BGT0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

284592:DEHA2F22594g
gene id: 284592:DEHA2F22594g
uniprot id: Q6BKE6
names: Similarity
messages: Belongs to the oligoribonuclease family.

284592:DEHA2B15862g
gene id: 284592:DEHA2B15862g
uniprot id: Q6BVX8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

284592:DEHA2F22198g
gene id: 284592:DEHA2F22198g
uniprot id: Q6BKG3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

284592:DEHA2B05742g
gene id: 284592:DEHA2B05742g
uniprot id: Q6BX59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2F22088g
gene id: 284592:DEHA2F22088g
uniprot id: Q6BKG8
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

284592:DEHA2G20152g
gene id: 284592:DEHA2G20152g
uniprot id: Q6BHA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

284592:DEHA2B01012g
gene id: 284592:DEHA2B01012g
uniprot id: Q6BXQ8
names: Function
names: Similarity
messages: Belongs to the MBF1 family.
messages: Transcriptional coactivator that stimulates transcriptional activity by bridging regulatory proteins and TBP, thereby recruiting TBP to promoters occupied by DNA-binding regulators.

284592:DEHA2F15422g
gene id: 284592:DEHA2F15422g
uniprot id: Q6BL90
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

284592:DEHA2C00858g
gene id: 284592:DEHA2C00858g
uniprot id: Q6BVQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

284592:DEHA2F26202g
gene id: 284592:DEHA2F26202g
uniprot id: Q6BJZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C1D family.
messages: Nucleus
messages: Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites.

284592:DEHA2F20020g
gene id: 284592:DEHA2F20020g
uniprot id: B5RUJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Nucleus

284592:DEHA2D05192g
gene id: 284592:DEHA2D05192g
uniprot id: Q6BSX8
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E24024g
gene id: 284592:DEHA2E24024g
uniprot id: B5RU67
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284592:DEHA2F24486g
gene id: 284592:DEHA2F24486g
uniprot id: Q6BK66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCS1 family.
messages: Binds 2 copper ions per subunit.
messages: Copper chaperone for superoxide dismutase 1 (SOD1). Binds copper ions and delivers them specifically to SOD1 (By similarity).
messages: Cytoplasm

284592:DEHA2C15708g
gene id: 284592:DEHA2C15708g
uniprot id: Q6BTV3
names: Similarity
messages: Belongs to the OPI10 family.

284592:DEHA2C08976g
gene id: 284592:DEHA2C08976g
uniprot id: Q6BUQ2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Phosphorylation of the TEDS site (Ser-364) is required for the polarization of the actin cytoskeleton. Phosphorylation probably activates the myosin-I ATPase activity (By similarity).
messages: The myosin motor domain displays actin-stimulated ATPase activity and generates a mechanochemical force.
messages: The tail domain participates in molecular interactions that specify the role of the motor domain (By similarity). It is composed of several tail homology (TH) domains, namely a putative phospholipid-binding myosin tail domain (also named TH1), an Ala- and Pro-rich domain (TH2), followed by an SH3 domain and a C-terminal acidic domain (TH3).
messages: Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex (By similarity).
messages: actin patch

284592:DEHA2E00902g
gene id: 284592:DEHA2E00902g
uniprot id: Q6BR02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2B16236g
gene id: 284592:DEHA2B16236g
uniprot id: B5RSX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284592:DEHA2E00814g
gene id: 284592:DEHA2E00814g
uniprot id: Q6BR06
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284592:DEHA2E13948g
gene id: 284592:DEHA2E13948g
uniprot id: Q6BPF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRM1 family.
messages: Cell membrane
messages: Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.

284592:DEHA2E06864g
gene id: 284592:DEHA2E06864g
uniprot id: Q6BQB3
names: Similarity
messages: Belongs to the peptidase M20A family.

284592:DEHA2B05280g
gene id: 284592:DEHA2B05280g
uniprot id: Q6BX77
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

284592:DEHA2G19382g
gene id: 284592:DEHA2G19382g
uniprot id: Q6BHD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

284592:DEHA2E24376g
gene id: 284592:DEHA2E24376g
uniprot id: B5RU70
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

284592:DEHA2E18590g
gene id: 284592:DEHA2E18590g
uniprot id: Q6BNW0
names: Similarity
messages: Belongs to the cytochrome P450 family.

284592:DEHA2E05940g
gene id: 284592:DEHA2E05940g
uniprot id: Q6BQD9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

284592:DEHA2G24310g
gene id: 284592:DEHA2G24310g
uniprot id: Q6BGS5
names: Similarity
messages: Belongs to the FGGY kinase family.

284592:DEHA2G01606g
gene id: 284592:DEHA2G01606g
uniprot id: Q6BJL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Nucleus

284592:DEHA2A12738g
gene id: 284592:DEHA2A12738g
uniprot id: Q6BY37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERT1/acuK family.
messages: Nucleus
messages: Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes (By similarity).

284592:DEHA2G14696g
gene id: 284592:DEHA2G14696g
uniprot id: Q6BHZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

284592:DEHA2C15950g
gene id: 284592:DEHA2C15950g
uniprot id: Q6BTT9
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G16148g
gene id: 284592:DEHA2G16148g
uniprot id: Q6BHS4
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

284592:DEHA2B01496g
gene id: 284592:DEHA2B01496g
uniprot id: Q6BXN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP25 family.
messages: Mitochondrion inner membrane
messages: Probable mitochondrial mRNA stabilization factor.

284592:DEHA2B06138g
gene id: 284592:DEHA2B06138g
uniprot id: Q6BX41
names: Similarity
messages: Belongs to the LSM12 family.

284592:DEHA2E04246g
gene id: 284592:DEHA2E04246g
uniprot id: Q6BQL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MND1 family.
messages: Nucleus
messages: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.

284592:DEHA2B06908g
gene id: 284592:DEHA2B06908g
uniprot id: Q6BX10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

284592:DEHA2G18854g
gene id: 284592:DEHA2G18854g
uniprot id: B5RUV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

284592:DEHA2D06292g
gene id: 284592:DEHA2D06292g
uniprot id: Q6BST9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

284592:DEHA2B00594g
gene id: 284592:DEHA2B00594g
uniprot id: Q6BXS6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

284592:DEHA2F10934g
gene id: 284592:DEHA2F10934g
uniprot id: Q6BLT1
names: Function
names: Similarity
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.

284592:DEHA2A03542g
gene id: 284592:DEHA2A03542g
uniprot id: B5RSQ4
names: Function
names: Similarity
messages: Belongs to the dihydroxyacetone kinase (DAK) family.
messages: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.

284592:DEHA2D09262g
gene id: 284592:DEHA2D09262g
uniprot id: Q6BSF3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

284592:DEHA2F21846g
gene id: 284592:DEHA2F21846g
uniprot id: Q6BKI0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

284592:DEHA2E01166g
gene id: 284592:DEHA2E01166g
uniprot id: Q6BQZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2F06182g
gene id: 284592:DEHA2F06182g
uniprot id: Q6BME2
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

284592:DEHA2C16654g
gene id: 284592:DEHA2C16654g
uniprot id: Q6BTQ7
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

284592:DEHA2F16170g
gene id: 284592:DEHA2F16170g
uniprot id: Q6BL59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

284592:DEHA2F18150g
gene id: 284592:DEHA2F18150g
uniprot id: Q6BKX4
names: Similarity
messages: Belongs to the RMD1/sif2 family.

284592:DEHA2D01672g
gene id: 284592:DEHA2D01672g
uniprot id: Q6BTC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

284592:DEHA2D08800g
gene id: 284592:DEHA2D08800g
uniprot id: Q6BSH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

284592:DEHA2D10450g
gene id: 284592:DEHA2D10450g
uniprot id: Q6BSA0
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G15796g
gene id: 284592:DEHA2G15796g
uniprot id: Q6BHU2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

284592:DEHA2F11242g
gene id: 284592:DEHA2F11242g
uniprot id: Q6BLR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

284592:DEHA2C04092g
gene id: 284592:DEHA2C04092g
uniprot id: Q6BVA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small GTPase superfamily. SAR1 family.
messages: COPII is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex and SAR1.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SAR1 controls the coat assembly in a stepwise manner. Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex. These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated transport vesicles. Conversion to SAR1-GDP triggers coat release and recycles COPII subunits (By similarity).

284592:DEHA2C08734g
gene id: 284592:DEHA2C08734g
uniprot id: Q6BUR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2E06666g
gene id: 284592:DEHA2E06666g
uniprot id: Q6BQC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

284592:DEHA2A05588g
gene id: 284592:DEHA2A05588g
uniprot id: Q6BZ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom7 family.
messages: Membrane
messages: Mitochondrion outer membrane

284592:DEHA2C15532g
gene id: 284592:DEHA2C15532g
uniprot id: Q6BTV9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

284592:DEHA2E04532g
gene id: 284592:DEHA2E04532g
uniprot id: Q6BQK3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Component of the mitochondrial large ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S) (By similarity).
messages: Mitochondrion

284592:DEHA2G20108g
gene id: 284592:DEHA2G20108g
uniprot id: Q6BHA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Nucleus

284592:DEHA2D04554g
gene id: 284592:DEHA2D04554g
uniprot id: Q6BT06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

284592:DEHA2A13684g
gene id: 284592:DEHA2A13684g
uniprot id: Q6BXZ5
names: Similarity
messages: Belongs to the LTV1 family.

284592:DEHA2F07700g
gene id: 284592:DEHA2F07700g
uniprot id: B5RUB7
names: Similarity
messages: Belongs to the histidine acid phosphatase family.

284592:DEHA2E18700g
gene id: 284592:DEHA2E18700g
uniprot id: Q6BNV6
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E22704g
gene id: 284592:DEHA2E22704g
uniprot id: Q6BND3
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

284592:DEHA2E01870g
gene id: 284592:DEHA2E01870g
uniprot id: Q6BQV8
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

284592:DEHA2G17886g
gene id: 284592:DEHA2G17886g
uniprot id: Q6BHK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts in the GPI biosynthetic pathway between GlcNAc-PI synthesis and GPI transfer to protein.
messages: Belongs to the PIGF family.
messages: Endoplasmic reticulum membrane

284592:DEHA2C12408g
gene id: 284592:DEHA2C12408g
uniprot id: Q6BUA5
names: Similarity
messages: Belongs to the IST1 family.

284592:DEHA2A04928g
gene id: 284592:DEHA2A04928g
uniprot id: Q6BZ34
names: Subcellular Location Annotation
messages: nuclear pore complex

284592:DEHA2B02838g
gene id: 284592:DEHA2B02838g
uniprot id: Q6BXI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy (By similarity).

284592:DEHA2G02948g
gene id: 284592:DEHA2G02948g
uniprot id: Q6BJF0
names: Similarity
messages: Belongs to the BLM10 family.

284592:DEHA2C07832g
gene id: 284592:DEHA2C07832g
uniprot id: Q6BUU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

284592:DEHA2C12848g
gene id: 284592:DEHA2C12848g
uniprot id: P00043
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme c group covalently per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

284592:DEHA2D04048g
gene id: 284592:DEHA2D04048g
uniprot id: Q6BT27
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity).
messages: Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284592:DEHA2F08558g
gene id: 284592:DEHA2F08558g
uniprot id: Q6BM37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion matrix

284592:DEHA2C03102g
gene id: 284592:DEHA2C03102g
uniprot id: B5RT66
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E23738g
gene id: 284592:DEHA2E23738g
uniprot id: Q6BN88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Cytoplasm
messages: Membrane
messages: Probable sterol 3-beta-glucosyltransferase that is not involved in cytoplasm to vacuole transport (Cvt), pexophagy or nonselective autophagy (By similarity).

284592:DEHA2G17402g
gene id: 284592:DEHA2G17402g
uniprot id: B5RUU7
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G12034g
gene id: 284592:DEHA2G12034g
uniprot id: Q6BIB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: cytoskeleton

284592:DEHA2F21516g
gene id: 284592:DEHA2F21516g
uniprot id: B5RUL3
names: Similarity
messages: Belongs to the PPP phosphatase family.

284592:DEHA2C05126g
gene id: 284592:DEHA2C05126g
uniprot id: Q6BV60
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

284592:DEHA2D16896g
gene id: 284592:DEHA2D16896g
uniprot id: Q6BRF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
messages: Interacts with the MHF histone-fold complex to form the FANCM-MHF complex.
messages: Nucleus

284592:DEHA2G18612g
gene id: 284592:DEHA2G18612g
uniprot id: Q6BHH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2C17490g
gene id: 284592:DEHA2C17490g
uniprot id: Q6BTL7
names: Function
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.
messages: Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP.

284592:DEHA2C16170g
gene id: 284592:DEHA2C16170g
uniprot id: Q6BTS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM RBM34 family.
messages: Involved in pre-25S rRNA processing.
messages: nucleolus

284592:DEHA2G11539g
gene id: 284592:DEHA2G11539g
uniprot id: B5RUQ8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

284592:DEHA2F02684g
gene id: 284592:DEHA2F02684g
uniprot id: Q6BMT7
names: Function
names: Similarity
messages: Belongs to the Rab GDI family.
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

284592:DEHA2F02354g
gene id: 284592:DEHA2F02354g
uniprot id: Q6BMV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER (By similarity). The SRP complex targets the ribosome-nascent chain complex to the SRP receptor (SR), which is anchored in the ER, where SR compaction and GTPase rearrangement drive cotranslational protein translocation into the ER (By similarity). Binds the 7SL RNA, srp72 binds to this complex subsequently (By similarity). The SRP complex possibly participates in the elongation arrest function (By similarity).
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Heterodimer with SRP72 (By similarity). SRP68-SRP72 heterodimer formation is stabilized by the presence of 7SL RNA (By similarity). Component of a fungal signal recognition particle (SRP) complex that consists of a 7SL RNA molecule (scR1) and at least six protein subunits: SRP72, SRP68, SRP54, SEC65, SRP21 and SRP14 (By similarity).
messages: nucleolus

284592:DEHA2F12474g
gene id: 284592:DEHA2F12474g
uniprot id: W0TYT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

284592:DEHA2G12232g
gene id: 284592:DEHA2G12232g
uniprot id: Q6BIA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Delta(4)-fatty-acid desaturase which introduces a double bond at the 4-position in the long-chain base (LCB) of ceramides.
messages: Membrane

284592:DEHA2E07106g
gene id: 284592:DEHA2E07106g
uniprot id: B5RTW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETT1 family.
messages: Nucleus
messages: Required for correct translation termination and probably involved in regulation of hypoxic gene expression.

284592:DEHA2G18150g
gene id: 284592:DEHA2G18150g
uniprot id: Q6BHJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

284592:DEHA2F25278g
gene id: 284592:DEHA2F25278g
uniprot id: Q6BK32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

284592:DEHA2D16434g
gene id: 284592:DEHA2D16434g
uniprot id: B5RTJ3
names: Similarity
messages: Belongs to the cyclin family.

284592:DEHA2B03102g
gene id: 284592:DEHA2B03102g
uniprot id: Q6BXH0
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2F24244g
gene id: 284592:DEHA2F24244g
uniprot id: B5RUM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Sterol O-acyltransferase that catalyzes the formation of stery esters.

284592:DEHA2B14124g
gene id: 284592:DEHA2B14124g
uniprot id: Q6BW60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKN1/KRE6 family.
messages: Membrane

284592:DEHA2E04906g
gene id: 284592:DEHA2E04906g
uniprot id: B5RTV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

284592:DEHA2F08052g
gene id: 284592:DEHA2F08052g
uniprot id: Q6BM61
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F19690g
gene id: 284592:DEHA2F19690g
uniprot id: Q6BKR8
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

284592:DEHA2E10076g
gene id: 284592:DEHA2E10076g
uniprot id: Q6BPX6
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G06820g
gene id: 284592:DEHA2G06820g
uniprot id: B5RV45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Chromosome
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Nucleus

284592:DEHA2B10098g
gene id: 284592:DEHA2B10098g
uniprot id: Q6BWM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.

284592:DEHA2D05346g
gene id: 284592:DEHA2D05346g
uniprot id: Q6BSX1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

284592:DEHA2C17116g
gene id: 284592:DEHA2C17116g
uniprot id: Q6BTN6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

284592:DEHA2F11286g
gene id: 284592:DEHA2F11286g
uniprot id: Q6BLR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

284592:DEHA2B11660g
gene id: 284592:DEHA2B11660g
uniprot id: Q6BWF9
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D13596g
gene id: 284592:DEHA2D13596g
uniprot id: Q6BRV2
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F00726g
gene id: 284592:DEHA2F00726g
uniprot id: Q6BN29
names: Similarity
messages: Belongs to the peptidase M20A family.

284592:DEHA2F07546g
gene id: 284592:DEHA2F07546g
uniprot id: Q6BM85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Mitochondrion inner membrane

284592:DEHA2B11000g
gene id: 284592:DEHA2B11000g
uniprot id: Q6BWI7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

284592:DEHA2E22418g
gene id: 284592:DEHA2E22418g
uniprot id: Q6BNE5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

284592:DEHA2A02310g
gene id: 284592:DEHA2A02310g
uniprot id: Q6BZD0
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

284592:DEHA2E08492g
gene id: 284592:DEHA2E08492g
uniprot id: Q6BQ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

284592:DEHA2C16280g
gene id: 284592:DEHA2C16280g
uniprot id: Q6BTS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0495 family.
messages: Membrane

284592:DEHA2D08954g
gene id: 284592:DEHA2D08954g
uniprot id: Q6BSG7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

284592:DEHA2G03410g
gene id: 284592:DEHA2G03410g
uniprot id: Q6BJC7
names: Subcellular Location Annotation
messages: nucleolus

284592:DEHA2F08844g
gene id: 284592:DEHA2F08844g
uniprot id: Q6BM25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
messages: Component of the SRB8-11 complex, a regulatory module of the Mediator complex.
messages: Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity).
messages: Nucleus

284592:DEHA2F12320g
gene id: 284592:DEHA2F12320g
uniprot id: Q6BLM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC12 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Guanine nucleotide-exchange factor (GEF) required for the formation or budding of transport vesicles from the ER.

284592:DEHA2B11968g
gene id: 284592:DEHA2B11968g
uniprot id: Q6BWE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFH5 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Microsome membrane
messages: Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane. Heme-binding protein that may play a role in organic oxidant-induced stress responses.

284592:DEHA2A01408g
gene id: 284592:DEHA2A01408g
uniprot id: Q6BZG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284592:DEHA2C11770g
gene id: 284592:DEHA2C11770g
uniprot id: Q6BUD3
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2A13266g
gene id: 284592:DEHA2A13266g
uniprot id: Q6BY13
names: Similarity
messages: Belongs to the TrpF family.

284592:DEHA2G24552g
gene id: 284592:DEHA2G24552g
uniprot id: Q6BGR2
names: Similarity
messages: Belongs to the VPS25 family.

284592:DEHA2F03388g
gene id: 284592:DEHA2F03388g
uniprot id: Q6BMQ8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

284592:DEHA2C12210g
gene id: 284592:DEHA2C12210g
uniprot id: Q6BUB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

284592:DEHA2D18700g
gene id: 284592:DEHA2D18700g
uniprot id: B5RTM6
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

284592:DEHA2C15312g
gene id: 284592:DEHA2C15312g
uniprot id: B5RTC3
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

284592:DEHA2F25520g
gene id: 284592:DEHA2F25520g
uniprot id: Q6BK22
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G13134g
gene id: 284592:DEHA2G13134g
uniprot id: Q6BI63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

284592:DEHA2E15224g
gene id: 284592:DEHA2E15224g
uniprot id: Q6BPA3
names: Subcellular Location Annotation
messages: Peroxisome membrane

284592:DEHA2B06798g
gene id: 284592:DEHA2B06798g
uniprot id: Q6BX15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

284592:DEHA2F27104g
gene id: 284592:DEHA2F27104g
uniprot id: Q6BJV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

284592:DEHA2B05500g
gene id: 284592:DEHA2B05500g
uniprot id: Q6BX70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

284592:DEHA2F18634g
gene id: 284592:DEHA2F18634g
uniprot id: Q6BKW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Mitochondrion membrane

284592:DEHA2B10846g
gene id: 284592:DEHA2B10846g
uniprot id: Q6BWJ4
names: Similarity
messages: Belongs to the OSBP family.

284592:DEHA2E04928g
gene id: 284592:DEHA2E04928g
uniprot id: Q6BQI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

284592:DEHA2E03146g
gene id: 284592:DEHA2E03146g
uniprot id: Q6BQQ7
names: Similarity
messages: Belongs to the calreticulin family.

284592:DEHA2F11330g
gene id: 284592:DEHA2F11330g
uniprot id: Q6BLR4
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.

284592:DEHA2A14344g
gene id: 284592:DEHA2A14344g
uniprot id: Q6BXW6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284592:DEHA2F08272g
gene id: 284592:DEHA2F08272g
uniprot id: Q6BM51
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

284592:DEHA2D04664g
gene id: 284592:DEHA2D04664g
uniprot id: Q6BT01
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

284592:DEHA2F12034g
gene id: 284592:DEHA2F12034g
uniprot id: Q6BLN3
names: Similarity
messages: Belongs to the FPG family.

284592:DEHA2D03322g
gene id: 284592:DEHA2D03322g
uniprot id: Q6BT58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic GTase family.
messages: Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.
messages: Nucleus
messages: Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate.

284592:DEHA2F18854g
gene id: 284592:DEHA2F18854g
uniprot id: B5RUJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

284592:DEHA2E17204g
gene id: 284592:DEHA2E17204g
uniprot id: Q6BP20
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

284592:DEHA2E02354g
gene id: 284592:DEHA2E02354g
uniprot id: B5RTT2
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

284592:DEHA2E06732g
gene id: 284592:DEHA2E06732g
uniprot id: Q6BQB9
names: Similarity
messages: Belongs to the ketopantoate reductase family.

284592:DEHA2E20152g
gene id: 284592:DEHA2E20152g
uniprot id: Q6BNN9
names: Function
names: Subcellular Location Annotation
messages: May be involved in a process influencing telomere capping.
messages: Vacuole

284592:DEHA2G08756g
gene id: 284592:DEHA2G08756g
uniprot id: Q6BIP4
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: As accessory component of the DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication.
messages: Heterotetramer. Consists of four subunits: POL2, DPB2, DPB3 and DPB4 (By similarity).
messages: In eukaryotes there are five DNA polymerases: alpha, beta, gamma, delta, and epsilon which are responsible for different reactions of DNA synthesis.
messages: Nucleus

284592:DEHA2C07568g
gene id: 284592:DEHA2C07568g
uniprot id: Q6BUV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

284592:DEHA2G06490g
gene id: 284592:DEHA2G06490g
uniprot id: Q6BIZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2E00792g
gene id: 284592:DEHA2E00792g
uniprot id: Q6BR07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2E12518g
gene id: 284592:DEHA2E12518g
uniprot id: B5RTZ9
names: Similarity
messages: Belongs to the CCZ1 family.

284592:DEHA2E19184g
gene id: 284592:DEHA2E19184g
uniprot id: B5RU44
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

284592:DEHA2E22462g
gene id: 284592:DEHA2E22462g
uniprot id: Q6BNE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

284592:DEHA2D08844g
gene id: 284592:DEHA2D08844g
uniprot id: Q6BSH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A component of the endosomal sorting required for transport complex III (ESCRT-III).
messages: Belongs to the SNF7 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB). Also required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH (By similarity).

284592:DEHA2G05016g
gene id: 284592:DEHA2G05016g
uniprot id: Q6BJ57
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

284592:DEHA2D12628g
gene id: 284592:DEHA2D12628g
uniprot id: Q6BRZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly (By similarity).

284592:DEHA2G15136g
gene id: 284592:DEHA2G15136g
uniprot id: Q6BHX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.

284592:DEHA2G10956g
gene id: 284592:DEHA2G10956g
uniprot id: Q6BIF2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

284592:DEHA2A07150g
gene id: 284592:DEHA2A07150g
uniprot id: Q6BYT3
names: Similarity
messages: Belongs to the PRP18 family.

284592:DEHA2E14740g
gene id: 284592:DEHA2E14740g
uniprot id: Q6BPC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Mitochondrion inner membrane

284592:DEHA2C14652g
gene id: 284592:DEHA2C14652g
uniprot id: Q6BTZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

284592:DEHA2C06622g
gene id: 284592:DEHA2C06622g
uniprot id: Q6BUZ6
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

284592:DEHA2F22748g
gene id: 284592:DEHA2F22748g
uniprot id: Q6BKD9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

284592:DEHA2B15048g
gene id: 284592:DEHA2B15048g
uniprot id: Q6BW17
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2F04268g
gene id: 284592:DEHA2F04268g
uniprot id: Q6BML9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP6 subfamily.
messages: Component of the SWR1 chromatin remodeling complex.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability (By similarity).
messages: Cytoplasm
messages: Nucleus
messages: cytoskeleton

284592:DEHA2E22968g
gene id: 284592:DEHA2E22968g
uniprot id: Q6BNC2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

284592:DEHA2C02618g
gene id: 284592:DEHA2C02618g
uniprot id: Q6BVH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

284592:DEHA2F19932g
gene id: 284592:DEHA2F19932g
uniprot id: Q6BKQ9
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

284592:DEHA2E16566g
gene id: 284592:DEHA2E16566g
uniprot id: Q6BP48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC15 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284592:DEHA2F24266g
gene id: 284592:DEHA2F24266g
uniprot id: Q6BK75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2E22484g
gene id: 284592:DEHA2E22484g
uniprot id: Q6BNE2
names: Similarity
messages: Belongs to the SUI1 family.

284592:DEHA2F25740g
gene id: 284592:DEHA2F25740g
uniprot id: B5RUN9
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F05368g
gene id: 284592:DEHA2F05368g
uniprot id: Q6BMH6
names: Similarity
messages: Belongs to the SPT2 family.

284592:DEHA2B16082g
gene id: 284592:DEHA2B16082g
uniprot id: Q6BVW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2E03410g
gene id: 284592:DEHA2E03410g
uniprot id: B5RTT7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

284592:DEHA2B00616g
gene id: 284592:DEHA2B00616g
uniprot id: Q6BXS5
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

284592:DEHA2A05940g
gene id: 284592:DEHA2A05940g
uniprot id: Q6BYY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG3 family.
messages: Endoplasmic reticulum membrane

284592:DEHA2B10164g
gene id: 284592:DEHA2B10164g
uniprot id: Q6BWM5
names: Similarity
messages: Belongs to the IMPACT family.

284592:DEHA2C03080g
gene id: 284592:DEHA2C03080g
uniprot id: Q6BVF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

284592:DEHA2F22374g
gene id: 284592:DEHA2F22374g
uniprot id: Q6BKF6
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

284592:DEHA2G20988g
gene id: 284592:DEHA2G20988g
uniprot id: Q6BH66
names: Function
names: Similarity
messages: Belongs to the peptidase C2 family. PalB/RIM13 subfamily.
messages: Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.

284592:DEHA2F09900g
gene id: 284592:DEHA2F09900g
uniprot id: Q6BLX7
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2F21890g
gene id: 284592:DEHA2F21890g
uniprot id: Q6BKH8
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

284592:DEHA2F20086g
gene id: 284592:DEHA2F20086g
uniprot id: Q6BKQ2
names: Similarity
messages: Belongs to the AAA ATPase family.

284592:DEHA2G14366g
gene id: 284592:DEHA2G14366g
uniprot id: Q6BI08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

284592:DEHA2E23320g
gene id: 284592:DEHA2E23320g
uniprot id: Q6BNA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

284592:DEHA2F13904g
gene id: 284592:DEHA2F13904g
uniprot id: Q6BLF3
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

284592:DEHA2B12870g
gene id: 284592:DEHA2B12870g
uniprot id: B5RSZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. RKM1 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase.

284592:DEHA2F06556g
gene id: 284592:DEHA2F06556g
uniprot id: Q6BMC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

284592:DEHA2E16104g
gene id: 284592:DEHA2E16104g
uniprot id: Q6BP67
names: Similarity
messages: Belongs to the FGGY kinase family.

284592:DEHA2G01452g
gene id: 284592:DEHA2G01452g
uniprot id: B5RV14
names: Similarity
messages: Belongs to the polyprenol kinase family.

284592:DEHA2F00550g
gene id: 284592:DEHA2F00550g
uniprot id: Q6BN37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

284592:DEHA2B01364g
gene id: 284592:DEHA2B01364g
uniprot id: Q6BXP3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM16/PAM16 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity).
messages: Heterodimer with PAM18. Component of the PAM complex, at least composed of mtHsp70, MGE1, TIM44, PAM16, PAM17 and PAM18 (By similarity).
messages: Mitochondrion inner membrane
messages: The J-like region, although related to the J domain does not stimulate ATPase activity of mtHSP70. It nevertheless mediates the heterodimerization with the J domain of PAM18 and is therefore essential for PAM complex function (By similarity).

284592:DEHA2F00990g
gene id: 284592:DEHA2F00990g
uniprot id: Q6BN16
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284592:DEHA2F23408g
gene id: 284592:DEHA2F23408g
uniprot id: Q6BKB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TAF4 family.
messages: Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription (By similarity).
messages: Nucleus
messages: The 1.2 MDa TFIID complex is composed of TATA binding protein (TBP) and the 14 TBP-associated factors.

284592:DEHA2A07172g
gene id: 284592:DEHA2A07172g
uniprot id: Q6BYT2
names: Subcellular Location Annotation
messages: Peroxisome membrane

284592:DEHA2E05236g
gene id: 284592:DEHA2E05236g
uniprot id: Q6BQH3
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

284592:DEHA2D14278g
gene id: 284592:DEHA2D14278g
uniprot id: Q6BRS1
names: Similarity
messages: Belongs to the MAPRE family.

284592:DEHA2F22902g
gene id: 284592:DEHA2F22902g
uniprot id: Q6BKD3
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

284592:DEHA2E16676g
gene id: 284592:DEHA2E16676g
uniprot id: Q6BP43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

284592:DEHA2F20262g
gene id: 284592:DEHA2F20262g
uniprot id: B5RUJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2C09482g
gene id: 284592:DEHA2C09482g
uniprot id: Q6BUM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRG9 family.
messages: Mitochondrion
messages: Required for respiratory activity and maintenance and expression of the mitochondrial genome.

284592:DEHA2F26400g
gene id: 284592:DEHA2F26400g
uniprot id: W0TYU2
names: Similarity
messages: Belongs to the APC10 family.

284592:DEHA2D01408g
gene id: 284592:DEHA2D01408g
uniprot id: Q6BTE1
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C05654g
gene id: 284592:DEHA2C05654g
uniprot id: Q6BV37
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

284592:DEHA2F09086g
gene id: 284592:DEHA2F09086g
uniprot id: Q6BM15
names: Similarity
messages: In the C-terminal section; belongs to the histidinol dehydrogenase family.

284592:DEHA2C05456g
gene id: 284592:DEHA2C05456g
uniprot id: B5RT79
names: Subcellular Location Annotation
messages: Cytoplasm

284592:DEHA2C06270g
gene id: 284592:DEHA2C06270g
uniprot id: Q6BV09
names: Similarity
messages: Belongs to the sulfiredoxin family.

284592:DEHA2G24904g
gene id: 284592:DEHA2G24904g
uniprot id: Q6BGP6
names: Similarity
messages: Belongs to the PhyH family.

284592:DEHA2D01474g
gene id: 284592:DEHA2D01474g
uniprot id: Q6BTD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2F09768g
gene id: 284592:DEHA2F09768g
uniprot id: Q6BLY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

284592:DEHA2G07040g
gene id: 284592:DEHA2G07040g
uniprot id: Q6BIW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

284592:DEHA2C15290g
gene id: 284592:DEHA2C15290g
uniprot id: Q6BTW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

284592:DEHA2B06116g
gene id: 284592:DEHA2B06116g
uniprot id: Q6BX42
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

284592:DEHA2B03388g
gene id: 284592:DEHA2B03388g
uniprot id: Q6BXF7
names: Similarity
messages: Belongs to the cyclin family.

284592:DEHA2F02574g
gene id: 284592:DEHA2F02574g
uniprot id: Q6BMU4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation of histone H3 leads to transcriptional activation. H3K14ac formation by GCN5 is promoted by H3S10ph. H3K14ac can also be formed by ESA1. H3K56ac formation occurs predominantly in newly synthesized H3 molecules during G1, S and G2/M of the cell cycle and may be involved in DNA repair (By similarity).
messages: Belongs to the histone H3 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Mono-, di- and trimethylated by the COMPASS complex to form H3K4me1/2/3. H3K4me activates gene expression by regulating transcription elongation and plays a role in telomere length maintenance. H3K4me enrichment correlates with transcription levels, and occurs in a 5' to 3' gradient with H3K4me3 enrichment at the 5'-end of genes, shifting to H3K4me2 and then H3K4me1. Methylated by SET2 to form H3K36me. H3K36me represses gene expression. Methylated by DOT1 to form H3K79me. H3K79me is required for association of SIR proteins with telomeric regions and for telomeric silencing. The COMPASS-mediated formation of H3K4me2/3 and the DOT1-mediated formation of H3K79me require H2BK123ub1 (By similarity).
messages: Nucleus
messages: Phosphorylated by IPL1 to form H3S10ph. H3S10ph promotes subsequent H3K14ac formation by GCN5 and is required for transcriptional activation through TBP recruitment to the promoters (By similarity).
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H3K4me1/2/3 = mono-, di- and trimethylated Lys-5; H3K9ac = acetylated Lys-10; H3K9me1 = monomethylated Lys-10; H3S10ph = phosphorylated Ser-11; H3K14ac = acetylated Lys-15; H3K14me2 = dimethylated Lys-15; H3K18ac = acetylated Lys-19; H3K18me1 = monomethylated Lys-19; H3K23ac = acetylated Lys-24; H3K23me1 = monomethylated Lys-24; H3K27ac = acetylated Lys-28; H3K27me1/2/3 = mono-, di- and trimethylated Lys-28; H3K36ac = acetylated Lys-37; H3K36me1/2/3 = mono-, di- and trimethylated Lys-37; H3K56ac = acetylated Lys-57; H3K64ac = acetylated Lys-65; H3K79me1/2/3 = mono-, di- and trimethylated Lys-80.

284592:DEHA2C01430g
gene id: 284592:DEHA2C01430g
uniprot id: Q6BVM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

284592:DEHA2A05500g
gene id: 284592:DEHA2A05500g
uniprot id: Q6BZ08
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

284592:DEHA2E16258g
gene id: 284592:DEHA2E16258g
uniprot id: Q6BP62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

284592:DEHA2C08470g
gene id: 284592:DEHA2C08470g
uniprot id: Q6BUS3
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

284592:DEHA2B13178g
gene id: 284592:DEHA2B13178g
uniprot id: Q6BWA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

284592:DEHA2E14762g
gene id: 284592:DEHA2E14762g
uniprot id: Q6BPC4
names: Similarity
messages: Belongs to the TFIIB family.

284592:DEHA2B03344g
gene id: 284592:DEHA2B03344g
uniprot id: Q6BXF9
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2A02838g
gene id: 284592:DEHA2A02838g
uniprot id: Q6BZA3
names: Similarity
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.

284592:DEHA2F11440g
gene id: 284592:DEHA2F11440g
uniprot id: Q6BLQ9
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

284592:DEHA2B00528g
gene id: 284592:DEHA2B00528g
uniprot id: Q6BXS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2F16808g
gene id: 284592:DEHA2F16808g
uniprot id: B5RUI3
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

284592:DEHA2E02640g
gene id: 284592:DEHA2E02640g
uniprot id: Q6BQS6
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

284592:DEHA2D18920g
gene id: 284592:DEHA2D18920g
uniprot id: Q6BR62
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F08470g
gene id: 284592:DEHA2F08470g
uniprot id: B5RUC6
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2C01408g
gene id: 284592:DEHA2C01408g
uniprot id: Q6BVM6
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2B16104g
gene id: 284592:DEHA2B16104g
uniprot id: Q6BVW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2B05390g
gene id: 284592:DEHA2B05390g
uniprot id: Q6BX74
names: Similarity
messages: Belongs to the radical SAM superfamily. Biotin synthase family.

284592:DEHA2G17094g
gene id: 284592:DEHA2G17094g
uniprot id: Q6BHN9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Endomembrane system
messages: Endosome membrane
messages: May be required for cytoplasm to vacuole transport (Cvt) and pexophagy.
messages: The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization to the perivacuolar punctate structures.

284592:DEHA2F05676g
gene id: 284592:DEHA2F05676g
uniprot id: Q6BMG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

284592:DEHA2A04730g
gene id: 284592:DEHA2A04730g
uniprot id: Q6BZ42
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D00990g
gene id: 284592:DEHA2D00990g
uniprot id: Q6BTF7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

284592:DEHA2A12782g
gene id: 284592:DEHA2A12782g
uniprot id: Q6BY35
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

284592:DEHA2E08866g
gene id: 284592:DEHA2E08866g
uniprot id: Q6BQ28
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284592:DEHA2E22000g
gene id: 284592:DEHA2E22000g
uniprot id: Q6BNG2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-B family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Heterotetramer. Consists of 4 subunits: POL2, DPB2, DPB3 and DPB4 (By similarity).
messages: Nucleus
messages: The CysA-type zinc finger is required for PCNA-binding.
messages: The CysB motif binds 1 4Fe-4S cluster and is required for the formation of polymerase complexes.

284592:DEHA2G12694g
gene id: 284592:DEHA2G12694g
uniprot id: Q6BI84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DLT1 family.
messages: Membrane
messages: Required for growth under high-pressure and low-temperature conditions.

284592:DEHA2F00198g
gene id: 284592:DEHA2F00198g
uniprot id: B5RU74
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G06600g
gene id: 284592:DEHA2G06600g
uniprot id: Q6BIY7
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

284592:DEHA2D18018g
gene id: 284592:DEHA2D18018g
uniprot id: Q6BRA0
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

284592:DEHA2C07766g
gene id: 284592:DEHA2C07766g
uniprot id: Q6BUV1
names: Similarity
messages: Belongs to the RNase PH family.

284592:DEHA2F16764g
gene id: 284592:DEHA2F16764g
uniprot id: Q6BL32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNN1/MNT family.
messages: Golgi apparatus membrane
messages: Membrane

284592:DEHA2F27192g
gene id: 284592:DEHA2F27192g
uniprot id: Q6BJV1
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

284592:DEHA2G23958g
gene id: 284592:DEHA2G23958g
uniprot id: Q6BGU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NifU family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the core Fe-S cluster (ISC) assembly machinery.
messages: Mitochondrion matrix
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster assembly on ISU1 depends on the function of the cysteine desulfurase complex NFS1-ISD11, which serves as the sulfur donor for cluster synthesis, the iron-binding protein frataxin as the putative iron donor, and the electron transfer chain comprised of ferredoxin reductase and ferredoxin, which receive their electrons from NADH.

284592:DEHA2F02200g
gene id: 284592:DEHA2F02200g
uniprot id: Q6BMW0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

284592:DEHA2E10582g
gene id: 284592:DEHA2E10582g
uniprot id: Q6BPV3
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

284592:DEHA2G11770g
gene id: 284592:DEHA2G11770g
uniprot id: Q6BID2
names: Similarity
messages: Belongs to the SCC4/mau-2 family.

284592:DEHA2E15158g
gene id: 284592:DEHA2E15158g
uniprot id: Q6BPA6
names: Function
names: Similarity
messages: Belongs to the SNU71 family.
messages: Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway.

284592:DEHA2C12386g
gene id: 284592:DEHA2C12386g
uniprot id: Q6BUA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
messages: Self-associates. Interacts with NDL1 and dynein.
messages: cytoskeleton
messages: spindle pole

284592:DEHA2G09570g
gene id: 284592:DEHA2G09570g
uniprot id: Q6BIK9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL27 family.

284592:DEHA2E21252g
gene id: 284592:DEHA2E21252g
uniprot id: Q6BNJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the palI/RIM9 family.
messages: Cell membrane
messages: Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.

284592:DEHA2F17116g
gene id: 284592:DEHA2F17116g
uniprot id: B5RUI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

284592:DEHA2A09636g
gene id: 284592:DEHA2A09636g
uniprot id: Q6BYG9
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

284592:DEHA2D17732g
gene id: 284592:DEHA2D17732g
uniprot id: Q6BRB3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEF1 family.
messages: Cytoplasm
messages: Homodimer; may form higher order oligomers. Interacts with the large RNA polymerase II subunit RPO21; the interaction is direct and serves to bridge RPO21 to the Elongin complex in a manner dependent on transcription stress. Interacts with RAD26.
messages: Nucleus
messages: Proteolytically cleaved by the proteasome in response to transcription stress; the resulting N-terminal form constitutes the activated nuclear form and the C-terminal portion is degraded.
messages: Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled repair (TCR) factor RAD26 fails to efficiently displace stalled RNA polymerase II. Also involved in telomere length regulation. Binds DNA.
messages: Ubiquitinated.
messages: telomere

284592:DEHA2F24442g
gene id: 284592:DEHA2F24442g
uniprot id: Q6BK68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

284592:DEHA2D16764g
gene id: 284592:DEHA2D16764g
uniprot id: Q6BRF5
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

284592:DEHA2D04180g
gene id: 284592:DEHA2D04180g
uniprot id: Q6BT21
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

284592:DEHA2C10186g
gene id: 284592:DEHA2C10186g
uniprot id: Q6BUJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSA1 family.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

284592:DEHA2C12012g
gene id: 284592:DEHA2C12012g
uniprot id: Q6BUC1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

284592:DEHA2F01782g
gene id: 284592:DEHA2F01782g
uniprot id: B5RU79
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

284592:DEHA2G08118g
gene id: 284592:DEHA2G08118g
uniprot id: Q6BIS0
names: Similarity
messages: Belongs to the syntaxin family.

284592:DEHA2E21274g
gene id: 284592:DEHA2E21274g
uniprot id: Q6BNJ1
names: Function
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.
messages: Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP.

284592:DEHA2E16632g
gene id: 284592:DEHA2E16632g
uniprot id: Q6BP45
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
messages: Interacts with the U3 snoRNA and is associated with the 90S and 40S pre-ribosomes.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284592:DEHA2F01892g
gene id: 284592:DEHA2F01892g
uniprot id: Q6BMX4
names: Similarity
messages: Belongs to the 4HPPD family.

284592:DEHA2E14212g
gene id: 284592:DEHA2E14212g
uniprot id: Q6BPE7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

284592:DEHA2B09350g
gene id: 284592:DEHA2B09350g
uniprot id: Q6BWR2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

284592:DEHA2D13134g
gene id: 284592:DEHA2D13134g
uniprot id: Q6BRX5
names: Similarity
messages: Belongs to the PPP phosphatase family.

284592:DEHA2C04334g
gene id: 284592:DEHA2C04334g
uniprot id: Q6BV96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

284592:DEHA2E19668g
gene id: 284592:DEHA2E19668g
uniprot id: Q6BNQ9
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G18568g
gene id: 284592:DEHA2G18568g
uniprot id: Q6BHH4
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

284592:DEHA2D06402g
gene id: 284592:DEHA2D06402g
uniprot id: Q6BST4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

284592:DEHA2E09856g
gene id: 284592:DEHA2E09856g
uniprot id: Q6BPY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2D07502g
gene id: 284592:DEHA2D07502g
uniprot id: Q6BSN3
names: Similarity
messages: Belongs to the VPS37 family.

284592:DEHA2D07942g
gene id: 284592:DEHA2D07942g
uniprot id: B5RTF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

284592:DEHA2F01760g
gene id: 284592:DEHA2F01760g
uniprot id: Q6BMY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: May be involved in cellular response to stress. Required to maintain mitochondrial DNA (mtDNA) integrity and stability (By similarity).
messages: Mitochondrion inner membrane

284592:DEHA2G10252g
gene id: 284592:DEHA2G10252g
uniprot id: B5RUP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

284592:DEHA2F20042g
gene id: 284592:DEHA2F20042g
uniprot id: B5RUJ7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

284592:DEHA2A14168g
gene id: 284592:DEHA2A14168g
uniprot id: Q6BXX3
names: Function
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.
messages: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

284592:DEHA2C11506g
gene id: 284592:DEHA2C11506g
uniprot id: Q6BUE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PINX1 family.
messages: Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.
messages: nucleolus

284592:DEHA2E14586g
gene id: 284592:DEHA2E14586g
uniprot id: B5RU14
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E07612g
gene id: 284592:DEHA2E07612g
uniprot id: Q6BQ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

284592:DEHA2C17358g
gene id: 284592:DEHA2C17358g
uniprot id: Q6BTM3
names: Similarity
messages: Belongs to the SAPS family.

284592:DEHA2F03036g
gene id: 284592:DEHA2F03036g
uniprot id: Q6BMS3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

284592:DEHA2A08536g
gene id: 284592:DEHA2A08536g
uniprot id: Q6BYM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Nucleus

284592:DEHA2A11506g
gene id: 284592:DEHA2A11506g
uniprot id: Q6BY86
names: Cofactor
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 1 zinc ion per subunit.

284592:DEHA2C06314g
gene id: 284592:DEHA2C06314g
uniprot id: B5RT84
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2B08184g
gene id: 284592:DEHA2B08184g
uniprot id: Q6BWV7
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

284592:DEHA2G02134g
gene id: 284592:DEHA2G02134g
uniprot id: Q6BJI8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

284592:DEHA2C12694g
gene id: 284592:DEHA2C12694g
uniprot id: B5RTA7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284592:DEHA2C16236g
gene id: 284592:DEHA2C16236g
uniprot id: Q6BTS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1).
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.
messages: Vacuole membrane

284592:DEHA2G24596g
gene id: 284592:DEHA2G24596g
uniprot id: Q6BGR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

284592:DEHA2B10802g
gene id: 284592:DEHA2B10802g
uniprot id: Q6BWJ6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

284592:DEHA2D17688g
gene id: 284592:DEHA2D17688g
uniprot id: Q6BRB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAK10 family.
messages: Cytoplasm

284592:DEHA2D09130g
gene id: 284592:DEHA2D09130g
uniprot id: Q6BSF9
names: Function
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.

284592:DEHA2G04290g
gene id: 284592:DEHA2G04290g
uniprot id: Q6BJ88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2G11198g
gene id: 284592:DEHA2G11198g
uniprot id: B5RUQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

284592:DEHA2E14432g
gene id: 284592:DEHA2E14432g
uniprot id: Q6BPD7
names: Function
names: Similarity
messages: Belongs to the CCM1 family.
messages: RNA-binding protein involved in the specific removal of group I introns in mitochondrial encoded transcripts. Maintains the stability of the small subunit mitochondrial 15S rRNA and thus the expression of the mitochondrial genome.

284592:DEHA2A05786g
gene id: 284592:DEHA2A05786g
uniprot id: Q6BYZ5
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

284592:DEHA2E01386g
gene id: 284592:DEHA2E01386g
uniprot id: Q6BQY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2B13772g
gene id: 284592:DEHA2B13772g
uniprot id: B5RT02
names: Similarity
messages: Belongs to the peptidase C48 family.

284592:DEHA2D13838g
gene id: 284592:DEHA2D13838g
uniprot id: Q6BRU1
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

284592:DEHA2F14630g
gene id: 284592:DEHA2F14630g
uniprot id: Q6BLC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Mitochondrion
messages: Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria (By similarity).

284592:DEHA2G21318g
gene id: 284592:DEHA2G21318g
uniprot id: Q6BH52
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

284592:DEHA2D06138g
gene id: 284592:DEHA2D06138g
uniprot id: Q6BSU5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfate adenylyltransferase family.
messages: Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
messages: Cytoplasm
messages: Homohexamer. Dimer of trimers.
messages: The oligomerization domain is distantly related to APS kinases, but it is not functional and does not bind APS. It is required for oligomerization of the enzyme, although the oligomerization state has no effect on the catalytic activity of the enzyme.

284592:DEHA2E07986g
gene id: 284592:DEHA2E07986g
uniprot id: B5RTX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

284592:DEHA2F05896g
gene id: 284592:DEHA2F05896g
uniprot id: B5RUA5
names: Subcellular Location Annotation
messages: Cytoplasm

284592:DEHA2C13816g
gene id: 284592:DEHA2C13816g
uniprot id: Q6BU40
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C15686g
gene id: 284592:DEHA2C15686g
uniprot id: Q6BTV4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

284592:DEHA2F03542g
gene id: 284592:DEHA2F03542g
uniprot id: Q6BMQ1
names: Similarity
messages: Belongs to the yippee family.

284592:DEHA2D02508g
gene id: 284592:DEHA2D02508g
uniprot id: Q6BT93
names: Similarity
messages: Belongs to the PAF1 family.

284592:DEHA2A11198g
gene id: 284592:DEHA2A11198g
uniprot id: Q6BYA0
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

284592:DEHA2C05962g
gene id: 284592:DEHA2C05962g
uniprot id: Q6BV22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

284592:DEHA2F10318g
gene id: 284592:DEHA2F10318g
uniprot id: B5RUD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

284592:DEHA2G21560g
gene id: 284592:DEHA2G21560g
uniprot id: Q6BH41
names: Similarity
messages: Belongs to the cytidylyltransferase family.

284592:DEHA2G04664g
gene id: 284592:DEHA2G04664g
uniprot id: Q6BJ73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SPP2 family.
messages: Involved in spliceosome maturation and the first step of pre-mRNA splicing.
messages: Nucleus

284592:DEHA2E18898g
gene id: 284592:DEHA2E18898g
uniprot id: Q6BNU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Nucleus
messages: Possesses 5'->3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote termination of transcription by RNA polymerase II (By similarity).

284592:DEHA2F01540g
gene id: 284592:DEHA2F01540g
uniprot id: Q6BMZ0
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2B14168g
gene id: 284592:DEHA2B14168g
uniprot id: Q6BW58
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG9 family.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Forms a homotrimer with a solvated central pore, which is connected laterally to the cytosol through the cavity within each protomer. Acts as a lipid scramblase that uses its central pore to function: the central pore opens laterally to accommodate lipid headgroups, thereby enabling lipid flipping and redistribution of lipids added to the outer leaflet of ATG9-containing vesicles, thereby enabling growth into autophagosomes.
messages: Golgi apparatus membrane
messages: Homotrimer; forms a homotrimer with a central pore that forms a path between the two membrane leaflets.
messages: Phospholipid scramblase involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion. Required for mitophagy. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.
messages: Phosphorylated by ATG1. ATG1 phosphorylation is required for preautophagosome elongation.
messages: Preautophagosomal structure membrane

284592:DEHA2D06710g
gene id: 284592:DEHA2D06710g
uniprot id: Q6BSS0
names: Similarity
messages: Belongs to the peptidase A1 family.

284592:DEHA2D00352g
gene id: 284592:DEHA2D00352g
uniprot id: Q6BTI4
names: Subcellular Location Annotation
messages: telomere

284592:DEHA2B09548g
gene id: 284592:DEHA2B09548g
uniprot id: Q6BWQ3
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

284592:DEHA2E07458g
gene id: 284592:DEHA2E07458g
uniprot id: Q6BQ85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

284592:DEHA2B12078g
gene id: 284592:DEHA2B12078g
uniprot id: Q6BWE0
names: Subcellular Location Annotation
messages: Cytoplasm

284592:DEHA2G03784g
gene id: 284592:DEHA2G03784g
uniprot id: Q6BJB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-Q/OKP1 family.
messages: Nucleus

284592:DEHA2G10274g
gene id: 284592:DEHA2G10274g
uniprot id: Q6BIH9
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

284592:DEHA2G10406g
gene id: 284592:DEHA2G10406g
uniprot id: Q6BIH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus
messages: Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex.

284592:DEHA2E10780g
gene id: 284592:DEHA2E10780g
uniprot id: Q6BPU4
names: Similarity
messages: Belongs to the SHQ1 family.

284592:DEHA2A07612g
gene id: 284592:DEHA2A07612g
uniprot id: Q6BYR1
names: Similarity
messages: Belongs to the PP2C family.

284592:DEHA2G16060g
gene id: 284592:DEHA2G16060g
uniprot id: Q6BHS9
names: Function
names: Similarity
messages: Belongs to the SEC10 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

284592:DEHA2F24596g
gene id: 284592:DEHA2F24596g
uniprot id: Q6BK61
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.

284592:DEHA2A06952g
gene id: 284592:DEHA2A06952g
uniprot id: Q6BYU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

284592:DEHA2A01496g
gene id: 284592:DEHA2A01496g
uniprot id: Q6BZG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2B13750g
gene id: 284592:DEHA2B13750g
uniprot id: Q6BW75
names: Similarity
messages: Belongs to the peptidase M24B family.

284592:DEHA2G03586g
gene id: 284592:DEHA2G03586g
uniprot id: Q6BJC0
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

284592:DEHA2A03586g
gene id: 284592:DEHA2A03586g
uniprot id: Q6BZ71
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2A00638g
gene id: 284592:DEHA2A00638g
uniprot id: Q6BZK5
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D05676g
gene id: 284592:DEHA2D05676g
uniprot id: Q6BSV7
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E18348g
gene id: 284592:DEHA2E18348g
uniprot id: Q6BNX2
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

284592:DEHA2E21032g
gene id: 284592:DEHA2E21032g
uniprot id: Q6BNK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin NSP1/NUP62 family.
messages: Nucleus membrane

284592:DEHA2B11726g
gene id: 284592:DEHA2B11726g
uniprot id: Q6BWF6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SGF11 family.
messages: Component of the 1.8 MDa SAGA transcription coactivator-HAT complex. SAGA is built of 5 distinct domains with specialized functions. Within the SAGA complex, SUS1, SGF11, SGF73 and UBP8 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with SGF73, SUS1 and UBP8.
messages: Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). Involved in transcriptional regulation of a subset of SAGA-regulated genes. Within the SAGA complex, participates in a subcomplex, that specifically deubiquitinates histones H2B.
messages: Nucleus
messages: The C-terminal SGF11-type zinc-finger domain together with the C-terminal catalytic domain of UBP8 forms the 'catalytic lobe' of the SAGA deubiquitination module.
messages: The long N-terminal helix forms part of the 'assembly lobe' of the SAGA deubiquitination module.

284592:DEHA2A09922g
gene id: 284592:DEHA2A09922g
uniprot id: Q6BYF6
names: Similarity
messages: Belongs to the PPC synthetase family.

284592:DEHA2E12958g
gene id: 284592:DEHA2E12958g
uniprot id: Q6BPK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284592:DEHA2F22308g
gene id: 284592:DEHA2F22308g
uniprot id: Q6BKF8
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

284592:DEHA2D09218g
gene id: 284592:DEHA2D09218g
uniprot id: Q6BSF5
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

284592:DEHA2G20064g
gene id: 284592:DEHA2G20064g
uniprot id: B5RUW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

284592:DEHA2G13728g
gene id: 284592:DEHA2G13728g
uniprot id: B5RUS3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL19 family.

284592:DEHA2G11836g
gene id: 284592:DEHA2G11836g
uniprot id: B5RUR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

284592:DEHA2D08272g
gene id: 284592:DEHA2D08272g
uniprot id: Q6BSK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM31/MDM32 family.
messages: Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.
messages: Mitochondrion inner membrane

284592:DEHA2A09460g
gene id: 284592:DEHA2A09460g
uniprot id: Q6BYH8
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

284592:DEHA2B12562g
gene id: 284592:DEHA2B12562g
uniprot id: Q6BWB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the NTC complex (or PRP19-associated complex). The NTC complex associates with the spliceosome after the release of the U1 and U4 snRNAs and forms the CWC spliceosome subcomplex reminiscent of a late-stage spliceosome.
messages: Belongs to the CWC21 family.
messages: Cytoplasm
messages: Involved in pre-mRNA splicing. May function at or prior to the first catalytic step of splicing at the catalytic center of the spliceosome. May do so by stabilizing the catalytic center or the position of the RNA substrate (By similarity).
messages: Nucleus

284592:DEHA2D16720g
gene id: 284592:DEHA2D16720g
uniprot id: B5RTJ4
names: Similarity
messages: Belongs to the SEC3 family.

284592:DEHA2D00704g
gene id: 284592:DEHA2D00704g
uniprot id: Q6BTH0
names: Subcellular Location Annotation
messages: telomere

284592:DEHA2E02860g
gene id: 284592:DEHA2E02860g
uniprot id: Q6BQR7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

284592:DEHA2G01122g
gene id: 284592:DEHA2G01122g
uniprot id: Q6BJN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2B05830g
gene id: 284592:DEHA2B05830g
uniprot id: Q6BX55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

284592:DEHA2E09636g
gene id: 284592:DEHA2E09636g
uniprot id: Q6BPZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

284592:DEHA2F00528g
gene id: 284592:DEHA2F00528g
uniprot id: Q6BN38
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E00154g
gene id: 284592:DEHA2E00154g
uniprot id: B5RTS1
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2G10714g
gene id: 284592:DEHA2G10714g
uniprot id: Q6BIG3
names: Similarity
messages: Belongs to the protein kinase superfamily.

284592:DEHA2G16764g
gene id: 284592:DEHA2G16764g
uniprot id: Q6BHQ1
names: Subunit
messages: Homodimer.

284592:DEHA2D13288g
gene id: 284592:DEHA2D13288g
uniprot id: Q6BRW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

284592:DEHA2C03696g
gene id: 284592:DEHA2C03696g
uniprot id: Q6BVC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNN1/MNT family.
messages: Golgi apparatus membrane
messages: Membrane

284592:DEHA2G13552g
gene id: 284592:DEHA2G13552g
uniprot id: Q6BI44
names: Similarity
messages: Belongs to the AIM6 family.

284592:DEHA2F05434g
gene id: 284592:DEHA2F05434g
uniprot id: Q6BMH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: Nucleus
messages: Responsible for methylating the 5'-cap structure of mRNAs.

284592:DEHA2C13354g
gene id: 284592:DEHA2C13354g
uniprot id: Q6BU60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

284592:DEHA2C04972g
gene id: 284592:DEHA2C04972g
uniprot id: Q6BV66
names: Similarity
messages: Belongs to the AAA ATPase family.

284592:DEHA2B15774g
gene id: 284592:DEHA2B15774g
uniprot id: B5RSW7
names: Similarity
messages: Belongs to the PAPS reductase family. CysH subfamily.

284592:DEHA2G13332g
gene id: 284592:DEHA2G13332g
uniprot id: Q6BI54
names: Similarity
messages: Belongs to the ketopantoate reductase family.

284592:DEHA2F20658g
gene id: 284592:DEHA2F20658g
uniprot id: Q6BKM5
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

284592:DEHA2B14366g
gene id: 284592:DEHA2B14366g
uniprot id: Q6BW50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

284592:DEHA2G18304g
gene id: 284592:DEHA2G18304g
uniprot id: Q6BHI5
names: Similarity
messages: Belongs to the HGH1 family.

284592:DEHA2C14674g
gene id: 284592:DEHA2C14674g
uniprot id: B5RTB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

284592:DEHA2E02992g
gene id: 284592:DEHA2E02992g
uniprot id: Q6BQR1
names: Similarity
messages: Belongs to the complex I LYR family.

284592:DEHA2D04444g
gene id: 284592:DEHA2D04444g
uniprot id: Q6BT10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.

284592:DEHA2B04686g
gene id: 284592:DEHA2B04686g
uniprot id: Q6BXA3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

284592:DEHA2D07766g
gene id: 284592:DEHA2D07766g
uniprot id: Q6BSM2
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
messages: Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

284592:DEHA2E19448g
gene id: 284592:DEHA2E19448g
uniprot id: Q6BNR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

284592:DEHA2D05038g
gene id: 284592:DEHA2D05038g
uniprot id: Q6BSY5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

284592:DEHA2E08536g
gene id: 284592:DEHA2E08536g
uniprot id: Q6BQ42
names: Similarity
messages: Belongs to the IFRD family.

284592:DEHA2A07656g
gene id: 284592:DEHA2A07656g
uniprot id: Q6BYQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

284592:DEHA2G22990g
gene id: 284592:DEHA2G22990g
uniprot id: B5RUZ2
names: Function
names: Similarity
messages: Belongs to the UDPGP type 1 family.
messages: Plays a central role as a glucosyl donor in cellular metabolic pathways.

284592:DEHA2A08646g
gene id: 284592:DEHA2A08646g
uniprot id: Q6BYL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Peroxisome

284592:DEHA2D10648g
gene id: 284592:DEHA2D10648g
uniprot id: Q6BS92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

284592:DEHA2G22550g
gene id: 284592:DEHA2G22550g
uniprot id: B5RUY0
names: Similarity
messages: Belongs to the threonine aldolase family.

284592:DEHA2G16654g
gene id: 284592:DEHA2G16654g
uniprot id: Q6BHQ6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

284592:DEHA2E11968g
gene id: 284592:DEHA2E11968g
uniprot id: Q6BPP2
names: Similarity
messages: Belongs to the cyclin family.

284592:DEHA2D12408g
gene id: 284592:DEHA2D12408g
uniprot id: Q6BS10
names: Similarity
messages: Belongs to the Fmt family.

284592:DEHA2D09636g
gene id: 284592:DEHA2D09636g
uniprot id: Q6BSD6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS27 family.
messages: Both IUM domains are necessary for efficient binding to ubiquitin.
messages: Component of the ESCRT-0 complex composed of HSE1 and VPS27.
messages: Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
messages: Endosome membrane
messages: The FYVE domain is involved in the binding to phosphatidylinositol 3-phosphate (PtdIns(3)P) which is required for the association to endosomal membranes.

284592:DEHA2E09130g
gene id: 284592:DEHA2E09130g
uniprot id: Q6BQ15
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

284592:DEHA2F01914g
gene id: 284592:DEHA2F01914g
uniprot id: Q6BMX3
names: Similarity
messages: Belongs to the EFG1/PHD1/stuA family.

284592:DEHA2B13090g
gene id: 284592:DEHA2B13090g
uniprot id: Q6BWA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase family.
messages: Cytoplasm

284592:DEHA2D14410g
gene id: 284592:DEHA2D14410g
uniprot id: Q6BRR6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

284592:DEHA2A12364g
gene id: 284592:DEHA2A12364g
uniprot id: Q6BY51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2A10604g
gene id: 284592:DEHA2A10604g
uniprot id: Q6BYC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

284592:DEHA2C00990g
gene id: 284592:DEHA2C00990g
uniprot id: Q6BVP7
names: Similarity
messages: Belongs to the FAH family.

284592:DEHA2G21538g
gene id: 284592:DEHA2G21538g
uniprot id: Q6BH42
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MMM1 family.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
messages: Endoplasmic reticulum membrane
messages: Homodimer. Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.
messages: The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.

284592:DEHA2G18040g
gene id: 284592:DEHA2G18040g
uniprot id: Q6BHJ7
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

284592:DEHA2D01936g
gene id: 284592:DEHA2D01936g
uniprot id: Q6BTB8
names: Similarity
messages: Belongs to the MUB1/samB family.

284592:DEHA2G15048g
gene id: 284592:DEHA2G15048g
uniprot id: Q6BHX6
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

284592:DEHA2F20900g
gene id: 284592:DEHA2F20900g
uniprot id: Q6BKL4
names: Similarity
messages: Belongs to the SUN family.

284592:DEHA2B03872g
gene id: 284592:DEHA2B03872g
uniprot id: Q6BXD8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

284592:DEHA2F05280g
gene id: 284592:DEHA2F05280g
uniprot id: Q6BMI1
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F11198g
gene id: 284592:DEHA2F11198g
uniprot id: Q6BLR9
names: Subcellular Location Annotation
messages: nuclear pore complex

284592:DEHA2D15576g
gene id: 284592:DEHA2D15576g
uniprot id: B5RTI9
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

284592:DEHA2D17710g
gene id: 284592:DEHA2D17710g
uniprot id: Q6BRB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NHP6 family.
messages: Chromosome
messages: DNA-binding protein that induces severe bending of DNA. Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex (By similarity).
messages: Nucleus
messages: Weakly associates with the stable SPT16-POB3 heterodimer to form the FACT complex.

284592:DEHA2C10164g
gene id: 284592:DEHA2C10164g
uniprot id: Q6BUJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Membrane
messages: nuclear pore complex

284592:DEHA2B08096g
gene id: 284592:DEHA2B08096g
uniprot id: Q6BWW1
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

284592:DEHA2F01034g
gene id: 284592:DEHA2F01034g
uniprot id: Q6BN14
names: Function
names: Similarity
messages: Belongs to the dihydroxyacetone kinase (DAK) family.
messages: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.

284592:DEHA2C12452g
gene id: 284592:DEHA2C12452g
uniprot id: B5RTA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

284592:DEHA2G23738g
gene id: 284592:DEHA2G23738g
uniprot id: Q6BGV0
names: Similarity
messages: Belongs to the TFIIB family.

284592:DEHA2G16918g
gene id: 284592:DEHA2G16918g
uniprot id: Q6BHP7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
messages: Heterodimer of an alpha and a beta subunit.

284592:DEHA2E18392g
gene id: 284592:DEHA2E18392g
uniprot id: Q6BNX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enhancer of polycomb family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M (By similarity).
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus

284592:DEHA2E08228g
gene id: 284592:DEHA2E08228g
uniprot id: Q6BQ54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: May mediate the reduction of outer membrane cytochrome b5.
messages: Mitochondrion outer membrane

284592:DEHA2A14014g
gene id: 284592:DEHA2A14014g
uniprot id: Q6BXY0
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

284592:DEHA2G09504g
gene id: 284592:DEHA2G09504g
uniprot id: Q6BIL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

284592:DEHA2E05368g
gene id: 284592:DEHA2E05368g
uniprot id: Q6BQG8
names: Function
names: Subcellular Location Annotation
messages: May act as a zinc-influx transporter.
messages: Membrane

284592:DEHA2D07700g
gene id: 284592:DEHA2D07700g
uniprot id: Q6BSM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

284592:DEHA2F22330g
gene id: 284592:DEHA2F22330g
uniprot id: Q6BKF7
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

284592:DEHA2A01342g
gene id: 284592:DEHA2A01342g
uniprot id: Q6BZH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.
messages: Belongs to the CNOT2/3/5 family.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2G16038g
gene id: 284592:DEHA2G16038g
uniprot id: Q6BHT0
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G20350g
gene id: 284592:DEHA2G20350g
uniprot id: Q6BH94
names: Similarity
messages: Belongs to the DNA polymerase delta/II small subunit family.

284592:DEHA2E04268g
gene id: 284592:DEHA2E04268g
uniprot id: Q6BQL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GMC oxidoreductase family.
messages: Long-chain fatty alcohol oxidase involved in the omega-oxidation pathway of lipid degradation.
messages: Peroxisome matrix

284592:DEHA2G18766g
gene id: 284592:DEHA2G18766g
uniprot id: Q6BHG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

284592:DEHA2D10736g
gene id: 284592:DEHA2D10736g
uniprot id: Q6BS89
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

284592:DEHA2D10032g
gene id: 284592:DEHA2D10032g
uniprot id: Q6BSB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity).
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1) (By similarity). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c'' (By similarity).
messages: Vacuole membrane

284592:DEHA2F11220g
gene id: 284592:DEHA2F11220g
uniprot id: Q6BLR8
names: Similarity
messages: Belongs to the PPase family.

284592:DEHA2B03168g
gene id: 284592:DEHA2B03168g
uniprot id: Q6BXG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

284592:DEHA2F12012g
gene id: 284592:DEHA2F12012g
uniprot id: Q6BLN4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

284592:DEHA2F01936g
gene id: 284592:DEHA2F01936g
uniprot id: Q6BMX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

284592:DEHA2D11462g
gene id: 284592:DEHA2D11462g
uniprot id: Q6BS55
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

284592:DEHA2G18524g
gene id: 284592:DEHA2G18524g
uniprot id: W0TYU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2G09482g
gene id: 284592:DEHA2G09482g
uniprot id: Q6BIL3
names: Similarity
messages: Belongs to the RNR ribonuclease family.

284592:DEHA2G05896g
gene id: 284592:DEHA2G05896g
uniprot id: Q6BJ18
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.

284592:DEHA2F26708g
gene id: 284592:DEHA2F26708g
uniprot id: Q6BJX1
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

284592:DEHA2E09328g
gene id: 284592:DEHA2E09328g
uniprot id: Q6BQ06
names: Subcellular Location Annotation
messages: Nucleus membrane

284592:DEHA2C00440g
gene id: 284592:DEHA2C00440g
uniprot id: Q6BVR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

284592:DEHA2F03674g
gene id: 284592:DEHA2F03674g
uniprot id: Q6BMP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.
messages: Nucleus

284592:DEHA2C17534g
gene id: 284592:DEHA2C17534g
uniprot id: Q6BTL5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in ribosome assembly.
messages: Associates with pre-ribosomal particles.
messages: Belongs to the DEAD box helicase family. DDX27/DRS1 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284592:DEHA2D02970g
gene id: 284592:DEHA2D02970g
uniprot id: Q6BT74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2C06710g
gene id: 284592:DEHA2C06710g
uniprot id: Q6BUZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GNT1 family.
messages: Golgi apparatus membrane
messages: N-acetylglucosaminyltransferase involved in the Golgi-specific modification of N-linked glycans.
messages: Vacuole membrane

284592:DEHA2E09020g
gene id: 284592:DEHA2E09020g
uniprot id: Q6BQ20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activates the ATG1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy. Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation. Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy. Finally, ATG13 is also required for glycogen storage during stationary phase (By similarity).
messages: Belongs to the ATG13 family. Fungi subfamily.
messages: Cytoplasm
messages: Interacts with ATG1 to form the ATG1-ATG13 kinase complex.
messages: Preautophagosomal structure

284592:DEHA2F20372g
gene id: 284592:DEHA2F20372g
uniprot id: Q6BKN9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284592:DEHA2E14388g
gene id: 284592:DEHA2E14388g
uniprot id: Q6BPD9
names: Similarity
messages: Belongs to the DDB1 family.

284592:DEHA2F10846g
gene id: 284592:DEHA2F10846g
uniprot id: Q6BLT6
names: Similarity
messages: Belongs to the TMA16 family.

284592:DEHA2D09768g
gene id: 284592:DEHA2D09768g
uniprot id: Q6BSD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

284592:DEHA2F10384g
gene id: 284592:DEHA2F10384g
uniprot id: B5RUD6
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2G22770g
gene id: 284592:DEHA2G22770g
uniprot id: Q6BGY4
names: Similarity
messages: Belongs to the universal ribosomal protein uS3 family.

284592:DEHA2G10978g
gene id: 284592:DEHA2G10978g
uniprot id: Q6B458
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

284592:DEHA2G19030g
gene id: 284592:DEHA2G19030g
uniprot id: Q6BHF4
names: Similarity
messages: Belongs to the peptidase M20A family.

284592:DEHA2A08800g
gene id: 284592:DEHA2A08800g
uniprot id: Q6BYK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
messages: Cell membrane
messages: The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.

284592:DEHA2B06512g
gene id: 284592:DEHA2B06512g
uniprot id: Q6BX27
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284592:DEHA2C17886g
gene id: 284592:DEHA2C17886g
uniprot id: B5RTD7
names: Similarity
messages: Belongs to the peptidase A1 family.

284592:DEHA2E06622g
gene id: 284592:DEHA2E06622g
uniprot id: Q6BQC5
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F08162g
gene id: 284592:DEHA2F08162g
uniprot id: Q6BM56
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

284592:DEHA2A11858g
gene id: 284592:DEHA2A11858g
uniprot id: Q6BY74
names: Similarity
messages: Belongs to the peptidase A1 family.

284592:DEHA2C17006g
gene id: 284592:DEHA2C17006g
uniprot id: Q6BTP1
names: Similarity
messages: Belongs to the PIGH family.

284592:DEHA2F08976g
gene id: 284592:DEHA2F08976g
uniprot id: Q6BM19
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

284592:DEHA2F19624g
gene id: 284592:DEHA2F19624g
uniprot id: Q6BKS1
names: Similarity
messages: Belongs to the peptidase S33 family.

284592:DEHA2E21560g
gene id: 284592:DEHA2E21560g
uniprot id: B5RU51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284592:DEHA2G04928g
gene id: 284592:DEHA2G04928g
uniprot id: Q6BJ61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.
messages: Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity).
messages: Mitochondrion matrix

284592:DEHA2A07370g
gene id: 284592:DEHA2A07370g
uniprot id: Q6BYS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

284592:DEHA2G07414g
gene id: 284592:DEHA2G07414g
uniprot id: Q6BIV1
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by ATP (By similarity). ATP binding is a prerequisite to magnesium and substrate binding. ATP binds to 2 of the subunits in the homotetramer inducing a closure of these 2 subunits and the release of the C-terminal loop, thereby activating the enzyme (By similarity).
messages: Belongs to the ISN1 family.
messages: Homotetramer.
messages: IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation.

284592:DEHA2G17600g
gene id: 284592:DEHA2G17600g
uniprot id: Q6BHL8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPK1 type 1 family.
messages: Has kinase activity and phosphorylates inositol-1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) to produce 1,2,3,4,5,6-hexakisphosphate (InsP6), also known as phytate.
messages: Nucleus
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

284592:DEHA2B12188g
gene id: 284592:DEHA2B12188g
uniprot id: Q6BWD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2A11528g
gene id: 284592:DEHA2A11528g
uniprot id: Q6BY85
names: Subcellular Location Annotation
messages: nucleolus

284592:DEHA2F21604g
gene id: 284592:DEHA2F21604g
uniprot id: Q6BKI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.

284592:DEHA2E16456g
gene id: 284592:DEHA2E16456g
uniprot id: Q6BP53
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

284592:DEHA2F11110g
gene id: 284592:DEHA2F11110g
uniprot id: Q6BLS3
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.

284592:DEHA2E20372g
gene id: 284592:DEHA2E20372g
uniprot id: Q6BNN2
names: Function
names: Similarity
messages: Belongs to the LCL2 family.
messages: Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.

284592:DEHA2E09988g
gene id: 284592:DEHA2E09988g
uniprot id: Q6BPX9
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F15268g
gene id: 284592:DEHA2F15268g
uniprot id: Q6BL97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

284592:DEHA2C05720g
gene id: 284592:DEHA2C05720g
uniprot id: Q6BV34
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

284592:DEHA2F10912g
gene id: 284592:DEHA2F10912g
uniprot id: Q6BLT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the palA/RIM20 family.
messages: Interacts with RIM101 by binding to its two YPX[LI] motifs.
messages: Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH. May act as a scaffold protein that recruits the calpain-like protease RIM13 via VPS32 to its substrate RIM101 (By similarity).

284592:DEHA2A05368g
gene id: 284592:DEHA2A05368g
uniprot id: Q6BZ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

284592:DEHA2A07744g
gene id: 284592:DEHA2A07744g
uniprot id: Q6BYQ4
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F14146g
gene id: 284592:DEHA2F14146g
uniprot id: Q6BLE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2C02090g
gene id: 284592:DEHA2C02090g
uniprot id: Q6BVJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GON7 family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 likely plays a supporting role to the catalytic subunit KAE1 in the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators (By similarity).
messages: Nucleus
messages: telomere

284592:DEHA2A11968g
gene id: 284592:DEHA2A11968g
uniprot id: Q6BY69
names: Similarity
messages: Belongs to the OMP decarboxylase family.

284592:DEHA2C02640g
gene id: 284592:DEHA2C02640g
uniprot id: Q6BVH5
names: Similarity
messages: Belongs to the COG3 family.

284592:DEHA2C03828g
gene id: 284592:DEHA2C03828g
uniprot id: Q6BVC1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the alternative oxidase family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.

284592:DEHA2G22308g
gene id: 284592:DEHA2G22308g
uniprot id: B5RUX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

284592:DEHA2B07942g
gene id: 284592:DEHA2B07942g
uniprot id: B5RT11
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

284592:DEHA2F00682g
gene id: 284592:DEHA2F00682g
uniprot id: Q6BN30
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

284592:DEHA2E05720g
gene id: 284592:DEHA2E05720g
uniprot id: Q6BQE9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated once deposited into chromatin.
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. H2A or its variant H2A.Z forms a heterodimer with H2B. H2A.Z associates with the VPS72/SWC2 subunit of the SWR1 chromatin remodeling complex. Interacts also with RBP1/DNA-directed RNA polymerase II largest subunit (By similarity).
messages: Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received. Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins. Required for the RNA polymerase II and SPT15/TBP recruitment to the target genes. Involved in chromosome stability (By similarity).

284592:DEHA2F11374g
gene id: 284592:DEHA2F11374g
uniprot id: Q6BLR2
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F22726g
gene id: 284592:DEHA2F22726g
uniprot id: Q6BKE0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

284592:DEHA2B01540g
gene id: 284592:DEHA2B01540g
uniprot id: Q6BXN6
names: Similarity
messages: Belongs to the KTI12 family.

284592:DEHA2B14410g
gene id: 284592:DEHA2B14410g
uniprot id: Q6BW47
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

284592:DEHA2E04510g
gene id: 284592:DEHA2E04510g
uniprot id: Q6BQK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

284592:DEHA2C02376g
gene id: 284592:DEHA2C02376g
uniprot id: Q6BVI6
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

284592:DEHA2D14212g
gene id: 284592:DEHA2D14212g
uniprot id: Q6BRS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

284592:DEHA2G19008g
gene id: 284592:DEHA2G19008g
uniprot id: Q6BHF5
names: Similarity
messages: Belongs to the peptidase M20A family.

284592:DEHA2C14762g
gene id: 284592:DEHA2C14762g
uniprot id: Q6BTZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.
messages: Vacuole membrane

284592:DEHA2F00968g
gene id: 284592:DEHA2F00968g
uniprot id: Q6BN17
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

284592:DEHA2B00286g
gene id: 284592:DEHA2B00286g
uniprot id: Q6BXU0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

284592:DEHA2G10054g
gene id: 284592:DEHA2G10054g
uniprot id: Q6BII7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

284592:DEHA2G23562g
gene id: 284592:DEHA2G23562g
uniprot id: Q6BGV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

284592:DEHA2F09702g
gene id: 284592:DEHA2F09702g
uniprot id: Q6BLY8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.
messages: The DHHC domain is required for palmitoyltransferase activity.

284592:DEHA2G06204g
gene id: 284592:DEHA2G06204g
uniprot id: B5RV41
names: Similarity
messages: Belongs to the MGMT family.

284592:DEHA2F17556g
gene id: 284592:DEHA2F17556g
uniprot id: Q6BKZ6
names: Similarity
messages: Belongs to the MOG1 family.

284592:DEHA2A03476g
gene id: 284592:DEHA2A03476g
uniprot id: B5RSQ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane
messages: May function both as a monomer and a homodimer.

284592:DEHA2A10758g
gene id: 284592:DEHA2A10758g
uniprot id: Q6BYB9
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

284592:DEHA2G16324g
gene id: 284592:DEHA2G16324g
uniprot id: Q6BHR6
names: Similarity
messages: Belongs to the type-1 OGG1 family.

284592:DEHA2C10450g
gene id: 284592:DEHA2C10450g
uniprot id: B5RT95
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C08954g
gene id: 284592:DEHA2C08954g
uniprot id: Q6BUQ3
names: Subcellular Location Annotation
messages: nucleolus

284592:DEHA2F05346g
gene id: 284592:DEHA2F05346g
uniprot id: Q6BMH8
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.

284592:DEHA2F13882g
gene id: 284592:DEHA2F13882g
uniprot id: Q6BLF4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Mitochondrion
messages: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

284592:DEHA2D01034g
gene id: 284592:DEHA2D01034g
uniprot id: W0TYR3
names: Similarity
messages: Belongs to the FMO family.

284592:DEHA2E09724g
gene id: 284592:DEHA2E09724g
uniprot id: Q6BPZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

284592:DEHA2B12914g
gene id: 284592:DEHA2B12914g
uniprot id: Q6BWB3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

284592:DEHA2E01056g
gene id: 284592:DEHA2E01056g
uniprot id: Q6BQZ9
names: Similarity
messages: Belongs to the DapA family.

284592:DEHA2C01892g
gene id: 284592:DEHA2C01892g
uniprot id: Q6BVK6
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E05104g
gene id: 284592:DEHA2E05104g
uniprot id: Q6BQH8
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

284592:DEHA2B07876g
gene id: 284592:DEHA2B07876g
uniprot id: Q6BWX0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

284592:DEHA2D16258g
gene id: 284592:DEHA2D16258g
uniprot id: Q6BRH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm.
messages: nucleolus

284592:DEHA2F04180g
gene id: 284592:DEHA2F04180g
uniprot id: Q6BMM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Nucleus

284592:DEHA2G16236g
gene id: 284592:DEHA2G16236g
uniprot id: B5RUU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

284592:DEHA2F16522g
gene id: 284592:DEHA2F16522g
uniprot id: Q6BL44
names: Subunit
messages: Consists of at least two heavy chains and a number of intermediate and light chains.

284592:DEHA2G12188g
gene id: 284592:DEHA2G12188g
uniprot id: Q6BIB0
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

284592:DEHA2F12826g
gene id: 284592:DEHA2F12826g
uniprot id: Q6BLK0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

284592:DEHA2C04004g
gene id: 284592:DEHA2C04004g
uniprot id: Q6BVB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

284592:DEHA2G02728g
gene id: 284592:DEHA2G02728g
uniprot id: B5RV24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

284592:DEHA2E06842g
gene id: 284592:DEHA2E06842g
uniprot id: Q6BQB4
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G00858g
gene id: 284592:DEHA2G00858g
uniprot id: Q6BJQ0
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2B02728g
gene id: 284592:DEHA2B02728g
uniprot id: Q6BXI4
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

284592:DEHA2B05522g
gene id: 284592:DEHA2B05522g
uniprot id: Q6BX69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284592:DEHA2A02860g
gene id: 284592:DEHA2A02860g
uniprot id: Q6BZA2
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

284592:DEHA2G09438g
gene id: 284592:DEHA2G09438g
uniprot id: Q6BIL4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PROPPIN family.
messages: Component of the PI(3,5)P2 regulatory complex.
messages: Endosome membrane
messages: Preautophagosomal structure membrane
messages: The L/FRRG motif is essential for the cytoplasm to vacuole transport (Cvt) pathway, for the recruitment of ATG8 and ATG16 to the PAS in nutrient-rich medium, and for its recruitment to and dissociation from the PAS under starvation conditions.
messages: The N-terminus might form a beta-propeller domain involved in specific binding to phosphatidylinositol 3,5-bisphosphate (PIP2), leading to the association of the protein to the membrane.
messages: The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct ATG9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity).
messages: Vacuole membrane

284592:DEHA2D04598g
gene id: 284592:DEHA2D04598g
uniprot id: Q6BT04
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

284592:DEHA2C05896g
gene id: 284592:DEHA2C05896g
uniprot id: B5RT81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2F19492g
gene id: 284592:DEHA2F19492g
uniprot id: Q6BKS7
names: Similarity
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.

284592:DEHA2B10890g
gene id: 284592:DEHA2B10890g
uniprot id: Q6BWJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

284592:DEHA2E08008g
gene id: 284592:DEHA2E08008g
uniprot id: Q6BQ63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284592:DEHA2C17688g
gene id: 284592:DEHA2C17688g
uniprot id: Q6BTK6
names: Similarity
messages: Belongs to the DapA family.

284592:DEHA2B12496g
gene id: 284592:DEHA2B12496g
uniprot id: Q6BWC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

284592:DEHA2G09834g
gene id: 284592:DEHA2G09834g
uniprot id: Q6BIJ7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2D09966g
gene id: 284592:DEHA2D09966g
uniprot id: Q6BSC1
names: Similarity
messages: Belongs to the WD repeat coronin family.

284592:DEHA2G15708g
gene id: 284592:DEHA2G15708g
uniprot id: Q6BHU6
names: Subcellular Location Annotation
messages: Vacuole

284592:DEHA2C07920g
gene id: 284592:DEHA2C07920g
uniprot id: Q6BUU5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

284592:DEHA2F12430g
gene id: 284592:DEHA2F12430g
uniprot id: Q6BLL7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

284592:DEHA2C15862g
gene id: 284592:DEHA2C15862g
uniprot id: Q6BTU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: May play a role in ribosome biogenesis.
messages: nucleolus
messages: nucleoplasm

284592:DEHA2G18502g
gene id: 284592:DEHA2G18502g
uniprot id: Q6BHH6
names: Similarity
messages: Belongs to the SDO1/SBDS family.

284592:DEHA2C15158g
gene id: 284592:DEHA2C15158g
uniprot id: Q6BTX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

284592:DEHA2C06798g
gene id: 284592:DEHA2C06798g
uniprot id: B5RT85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC2 family.
messages: Nucleus

284592:DEHA2E08316g
gene id: 284592:DEHA2E08316g
uniprot id: Q6BQ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284592:DEHA2F01144g
gene id: 284592:DEHA2F01144g
uniprot id: Q6BN08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins and is essential for cell growth. It interacts with other membrane proteins required for protein translocation. Upon binding to SEC62/63 complex, secretory precursor polypeptides may engage SEC61 to begin membrane penetration event. A cycle of assembly and disassembly of SEC62/63 from SEC61 may govern the activity of the translocase (By similarity).
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma.

284592:DEHA2A07854g
gene id: 284592:DEHA2A07854g
uniprot id: Q6BYP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SSU72 phosphatase family.
messages: Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. SSU72 is required for 3'-end formation of snoRNAs (By similarity).
messages: Component of the cleavage and polyadenylation factor (CPF) complex.
messages: Nucleus
messages: Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1).

284592:DEHA2D00132g
gene id: 284592:DEHA2D00132g
uniprot id: B5RTP6
names: Subcellular Location Annotation
messages: cell wall

284592:DEHA2D03366g
gene id: 284592:DEHA2D03366g
uniprot id: Q6BT56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

284592:DEHA2D09240g
gene id: 284592:DEHA2D09240g
uniprot id: Q6BSF4
names: Subcellular Location Annotation
messages: telomere

284592:DEHA2F10450g
gene id: 284592:DEHA2F10450g
uniprot id: B5RUD7
names: Similarity
messages: Belongs to the group II decarboxylase family.

284592:DEHA2G09724g
gene id: 284592:DEHA2G09724g
uniprot id: Q6BIK2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

284592:DEHA2B07326g
gene id: 284592:DEHA2B07326g
uniprot id: B5RSX8
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F04026g
gene id: 284592:DEHA2F04026g
uniprot id: B5RU72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

284592:DEHA2G17116g
gene id: 284592:DEHA2G17116g
uniprot id: Q6BHN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

284592:DEHA2B12430g
gene id: 284592:DEHA2B12430g
uniprot id: Q6BWC4
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

284592:DEHA2G10296g
gene id: 284592:DEHA2G10296g
uniprot id: Q6BIH8
names: Function
messages: Cleaves A-5'-PPP-5'A to yield AMP and ADP. Can cleave all dinucleoside polyphosphates, provided the phosphate chain contains at least 3 phosphates and that 1 of the 2 bases composing the nucleotide is a purine. Is most effective on dinucleoside triphosphates. Negatively regulates intracellular dinucleoside polyphosphate levels, which elevate following heat shock.

284592:DEHA2A07480g
gene id: 284592:DEHA2A07480g
uniprot id: Q6BYR7
names: Similarity
messages: Belongs to the anthranilate synthase component I family.

284592:DEHA2A11220g
gene id: 284592:DEHA2A11220g
uniprot id: Q6BY99
names: Similarity
messages: Belongs to the PP2C family.

284592:DEHA2E01276g
gene id: 284592:DEHA2E01276g
uniprot id: Q6BQY8
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C17556g
gene id: 284592:DEHA2C17556g
uniprot id: Q6BTL4
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D05764g
gene id: 284592:DEHA2D05764g
uniprot id: Q6BSV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET5 subfamily.
messages: Cytoplasm
messages: It is uncertain whether Met-1 or Met-2 is the initiator.
messages: Nucleus
messages: Putative protein lysine methyltransferase.

284592:DEHA2F09416g
gene id: 284592:DEHA2F09416g
uniprot id: Q6BM01
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

284592:DEHA2D01892g
gene id: 284592:DEHA2D01892g
uniprot id: Q6BTC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family. PreP subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Degrades mitochondrial transit peptides after their cleavage in the intermembrane space or in the matrix, and presequence peptides; clearance of these peptides is required to keep the presequence processing machinery running (By similarity). Preferentially cleaves the N-terminal side of paired basic amino acid residues (By similarity). Also degrades other unstructured peptides (By similarity). May function as an ATP-dependent peptidase as opposed to a metalloendopeptidase (By similarity).
messages: Mitochondrion intermembrane space
messages: Mitochondrion matrix
messages: Monomer and homodimer; homodimerization is induced by binding of the substrate.

284592:DEHA2B09636g
gene id: 284592:DEHA2B09636g
uniprot id: Q6BWP7
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

284592:DEHA2B07216g
gene id: 284592:DEHA2B07216g
uniprot id: Q6BWZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWC5 family.
messages: Component of the SWR1 chromatin remodeling complex.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability (By similarity).
messages: Nucleus

284592:DEHA2C02002g
gene id: 284592:DEHA2C02002g
uniprot id: Q6BVK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to keep the TOM and the TIM23 complexes in close contact. At some point, it is released from the TOM23 complex to allow protein translocation into the mitochondrial matrix (By similarity).
messages: Mitochondrion inner membrane

284592:DEHA2D05566g
gene id: 284592:DEHA2D05566g
uniprot id: Q6BSW1
names: Similarity
messages: Belongs to the BolA/IbaG family.

284592:DEHA2F26840g
gene id: 284592:DEHA2F26840g
uniprot id: Q6BJW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Secreted

284592:DEHA2E07524g
gene id: 284592:DEHA2E07524g
uniprot id: Q6BQ82
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F11154g
gene id: 284592:DEHA2F11154g
uniprot id: Q6BLS1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

284592:DEHA2E09812g
gene id: 284592:DEHA2E09812g
uniprot id: Q6BPY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Nucleus

284592:DEHA2D12584g
gene id: 284592:DEHA2D12584g
uniprot id: Q6BS01
names: Similarity
messages: Belongs to the heat shock protein 70 family.

284592:DEHA2F25256g
gene id: 284592:DEHA2F25256g
uniprot id: Q6BK33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

284592:DEHA2G22330g
gene id: 284592:DEHA2G22330g
uniprot id: Q6BH08
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G16984g
gene id: 284592:DEHA2G16984g
uniprot id: Q6BHP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUR1 family.
messages: Member of a perinuclear network that controls recombination at multiple loci to maintain genome stability. Required for rDNA repeat stability.
messages: Membrane
messages: Nucleus membrane

284592:DEHA2D00308g
gene id: 284592:DEHA2D00308g
uniprot id: Q6BTI6
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C05764g
gene id: 284592:DEHA2C05764g
uniprot id: Q6BV32
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

284592:DEHA2C12056g
gene id: 284592:DEHA2C12056g
uniprot id: Q6BUB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

284592:DEHA2E18920g
gene id: 284592:DEHA2E18920g
uniprot id: Q6BNU6
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E16698g
gene id: 284592:DEHA2E16698g
uniprot id: Q6BP42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2E03608g
gene id: 284592:DEHA2E03608g
uniprot id: Q6BQN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

284592:DEHA2F08404g
gene id: 284592:DEHA2F08404g
uniprot id: Q6BM45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284592:DEHA2E12320g
gene id: 284592:DEHA2E12320g
uniprot id: Q6BPM8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284592:DEHA2F17710g
gene id: 284592:DEHA2F17710g
uniprot id: Q6BKZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PAM17 family.
messages: Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Component of the PAM complex, at least composed of mtHsp70 (SSC1), MGE1, TIM44, PAM16, PAM17 and PAM18.
messages: Mitochondrion inner membrane

284592:DEHA2C13178g
gene id: 284592:DEHA2C13178g
uniprot id: Q6BU68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome subunit S5B/HSM3 family.
messages: Cytoplasm
messages: Involved in DNA mismatch repair in slow-growing cells. Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the 19S regulatory complex (RC) (By similarity).

284592:DEHA2F07656g
gene id: 284592:DEHA2F07656g
uniprot id: Q6BM81
names: Cofactor
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.

284592:DEHA2F26356g
gene id: 284592:DEHA2F26356g
uniprot id: Q6BJY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ECO subfamily.
messages: Nucleus
messages: Probable acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by acetylating the cohesin complex component SMC3 (By similarity).

284592:DEHA2B08800g
gene id: 284592:DEHA2B08800g
uniprot id: Q6BWT1
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2F06798g
gene id: 284592:DEHA2F06798g
uniprot id: Q6BMB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

284592:DEHA2G03102g
gene id: 284592:DEHA2G03102g
uniprot id: Q6BJE1
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2C02420g
gene id: 284592:DEHA2C02420g
uniprot id: Q6BVI4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

284592:DEHA2A02442g
gene id: 284592:DEHA2A02442g
uniprot id: B5RSP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCO1/2 family.
messages: Mitochondrion inner membrane

284592:DEHA2G09922g
gene id: 284592:DEHA2G09922g
uniprot id: Q6BIJ3
names: Similarity
messages: Belongs to the CDC6/cdc18 family.

284592:DEHA2E19558g
gene id: 284592:DEHA2E19558g
uniprot id: Q6BNR4
names: Similarity
messages: Belongs to the CENP-C/MIF2 family.

284592:DEHA2F06754g
gene id: 284592:DEHA2F06754g
uniprot id: Q6BMB8
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.

284592:DEHA2F17512g
gene id: 284592:DEHA2F17512g
uniprot id: Q6BKZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14 (By similarity).

284592:DEHA2E19866g
gene id: 284592:DEHA2E19866g
uniprot id: Q6BNQ1
names: Similarity
messages: Belongs to the p23/wos2 family.

284592:DEHA2C14190g
gene id: 284592:DEHA2C14190g
uniprot id: Q6BU21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2E03520g
gene id: 284592:DEHA2E03520g
uniprot id: Q6BQP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NOP10 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA.
messages: nucleolus

284592:DEHA2F08250g
gene id: 284592:DEHA2F08250g
uniprot id: Q6BM52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with cytochrome c oxidase (complex IV, CIV).
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2G08580g
gene id: 284592:DEHA2G08580g
uniprot id: Q6BIQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

284592:DEHA2E10648g
gene id: 284592:DEHA2E10648g
uniprot id: Q6BPV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2F02882g
gene id: 284592:DEHA2F02882g
uniprot id: Q6BMT0
names: Similarity
messages: Belongs to the EIS1 family.

284592:DEHA2E01573g
gene id: 284592:DEHA2E01573g
uniprot id: Q6BQX3
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2C05984g
gene id: 284592:DEHA2C05984g
uniprot id: Q6BV21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
messages: Mitochondrion outer membrane

284592:DEHA2D17358g
gene id: 284592:DEHA2D17358g
uniprot id: B5RTK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM MRD1 family.
messages: Nucleus

284592:DEHA2F04642g
gene id: 284592:DEHA2F04642g
uniprot id: B5RU95
names: Similarity
messages: Belongs to the cullin family.

284592:DEHA2F16412g
gene id: 284592:DEHA2F16412g
uniprot id: B5RUH9
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

284592:DEHA2G22176g
gene id: 284592:DEHA2G22176g
uniprot id: Q6BH13
names: Function
names: Similarity
messages: Belongs to the peptidase C14B family.
messages: Involved in cell death (apoptosis).

284592:DEHA2B08338g
gene id: 284592:DEHA2B08338g
uniprot id: B5RT13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GEP5 family.
messages: Essential for respiratory growth and required for maintenance of mtDNA. Required for cell survival in the absence of prohibitins.
messages: Mitochondrion

284592:DEHA2A09328g
gene id: 284592:DEHA2A09328g
uniprot id: Q6BYI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Cytoplasm

284592:DEHA2G03762g
gene id: 284592:DEHA2G03762g
uniprot id: Q6BJB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: nucleolus

284592:DEHA2A11110g
gene id: 284592:DEHA2A11110g
uniprot id: Q6BYA3
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

284592:DEHA2G13178g
gene id: 284592:DEHA2G13178g
uniprot id: B5RUR9
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

284592:DEHA2C17072g
gene id: 284592:DEHA2C17072g
uniprot id: B5RTD1
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F09812g
gene id: 284592:DEHA2F09812g
uniprot id: B5RUD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
messages: Mitochondrion outer membrane

284592:DEHA2C12650g
gene id: 284592:DEHA2C12650g
uniprot id: Q6BU94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the WD repeat PRL1/PRL2 family.
messages: Cytoplasm
messages: Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.
messages: Nucleus

284592:DEHA2B01672g
gene id: 284592:DEHA2B01672g
uniprot id: Q6BXN1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

284592:DEHA2C12034g
gene id: 284592:DEHA2C12034g
uniprot id: Q6BUC0
names: Subunit
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

284592:DEHA2F16610g
gene id: 284592:DEHA2F16610g
uniprot id: Q6BL39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

284592:DEHA2A05038g
gene id: 284592:DEHA2A05038g
uniprot id: Q6BZ29
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284592:DEHA2F17402g
gene id: 284592:DEHA2F17402g
uniprot id: Q6BL03
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284592:DEHA2G06270g
gene id: 284592:DEHA2G06270g
uniprot id: Q6BJ01
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284592:DEHA2D00374g
gene id: 284592:DEHA2D00374g
uniprot id: Q6BTI3
names: Similarity
messages: Belongs to the FAH family.

284592:DEHA2D10890g
gene id: 284592:DEHA2D10890g
uniprot id: Q6BS83
names: Similarity
messages: Belongs to the DOCK family.

284592:DEHA2D14322g
gene id: 284592:DEHA2D14322g
uniprot id: Q6BRR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

284592:DEHA2D07304g
gene id: 284592:DEHA2D07304g
uniprot id: B5RTE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

284592:DEHA2G06996g
gene id: 284592:DEHA2G06996g
uniprot id: Q6BIW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLASP family.
messages: Belongs to the TOG/XMAP215 family.
messages: spindle

284592:DEHA2G21890g
gene id: 284592:DEHA2G21890g
uniprot id: Q6BH26
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

284592:DEHA2A08602g
gene id: 284592:DEHA2A08602g
uniprot id: Q6BYL7
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

284592:DEHA2G14300g
gene id: 284592:DEHA2G14300g
uniprot id: Q6BI11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

284592:DEHA2E06050g
gene id: 284592:DEHA2E06050g
uniprot id: Q6BQD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-Z subfamily.
messages: Cytoplasm

284592:DEHA2D05588g
gene id: 284592:DEHA2D05588g
uniprot id: Q6BSW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2D14894g
gene id: 284592:DEHA2D14894g
uniprot id: B5RTI5
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

284592:DEHA2B10406g
gene id: 284592:DEHA2B10406g
uniprot id: Q6BWL4
names: Similarity
messages: Belongs to the arginase family.

284592:DEHA2F08998g
gene id: 284592:DEHA2F08998g
uniprot id: Q6BM18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG27 family.
messages: Cytoplasmic vesicle membrane
messages: Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre-autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity).
messages: Golgi apparatus membrane
messages: Mitochondrion membrane
messages: Preautophagosomal structure membrane

284592:DEHA2B02134g
gene id: 284592:DEHA2B02134g
uniprot id: B5RT27
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C06138g
gene id: 284592:DEHA2C06138g
uniprot id: Q6BV14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DASH complex DAD2 family.
messages: Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
messages: Nucleus
messages: The DASH complex oligomerizes to form rings that encircle the microtubules.
messages: kinetochore
messages: spindle

284592:DEHA2E24112g
gene id: 284592:DEHA2E24112g
uniprot id: Q6BN72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

284592:DEHA2C10846g
gene id: 284592:DEHA2C10846g
uniprot id: Q6BUG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).

284592:DEHA2D13882g
gene id: 284592:DEHA2D13882g
uniprot id: Q6BRT9
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2D09394g
gene id: 284592:DEHA2D09394g
uniprot id: Q6BSE7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.
messages: Inhibited by both FK506 and rapamycin.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
messages: nucleolus

284592:DEHA2G14256g
gene id: 284592:DEHA2G14256g
uniprot id: B5RUS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Vacuole membrane

284592:DEHA2B04378g
gene id: 284592:DEHA2B04378g
uniprot id: Q6BXB7
names: Subcellular Location Annotation
names: Subunit
messages: Component of the mitochondrial large ribosomal subunit.
messages: Mitochondrion

284592:DEHA2G11000g
gene id: 284592:DEHA2G11000g
uniprot id: Q6BIF0
names: Function
names: Similarity
messages: Belongs to the BUD3 family.
messages: Co-assembles with BUD4 at bud sites. BUD4 and BUD3 may cooperate to recognize a spatial landmark (the neck filaments) during mitosis and they subsequently become a landmark for establishing the axial budding pattern in G1 (By similarity).

284592:DEHA2G00924g
gene id: 284592:DEHA2G00924g
uniprot id: Q6BJP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

284592:DEHA2F13332g
gene id: 284592:DEHA2F13332g
uniprot id: B5RUG1
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

284592:DEHA2E17688g
gene id: 284592:DEHA2E17688g
uniprot id: Q6BP01
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

284592:DEHA2G12672g
gene id: 284592:DEHA2G12672g
uniprot id: Q6BI85
names: Similarity
messages: Belongs to the SEN15 family.

284592:DEHA2D05368g
gene id: 284592:DEHA2D05368g
uniprot id: Q6BSX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

284592:DEHA2G07546g
gene id: 284592:DEHA2G07546g
uniprot id: Q6BIU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

284592:DEHA2E20834g
gene id: 284592:DEHA2E20834g
uniprot id: Q6BNL2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

284592:DEHA2G15092g
gene id: 284592:DEHA2G15092g
uniprot id: Q6BHX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTC5 family.
messages: Cytoplasm
messages: May be involved in a process influencing telomere capping.

284592:DEHA2E10406g
gene id: 284592:DEHA2E10406g
uniprot id: Q6BPW2
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

284592:DEHA2F02838g
gene id: 284592:DEHA2F02838g
uniprot id: Q6BMT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OCA5 family.
messages: Cytoplasm

284592:DEHA2G02420g
gene id: 284592:DEHA2G02420g
uniprot id: Q6BJH3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

284592:DEHA2F07480g
gene id: 284592:DEHA2F07480g
uniprot id: Q6BM88
names: Similarity
messages: Belongs to the sorting nexin family.

284592:DEHA2C15884g
gene id: 284592:DEHA2C15884g
uniprot id: Q6BTU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Mitochondrion inner membrane

284592:DEHA2D12540g
gene id: 284592:DEHA2D12540g
uniprot id: Q6BS03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

284592:DEHA2B09922g
gene id: 284592:DEHA2B09922g
uniprot id: Q6BWN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Nucleus

284592:DEHA2F17798g
gene id: 284592:DEHA2F17798g
uniprot id: Q6BKY7
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

284592:DEHA2E04576g
gene id: 284592:DEHA2E04576g
uniprot id: Q6BQK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
messages: Endoplasmic reticulum membrane

284592:DEHA2A05654g
gene id: 284592:DEHA2A05654g
uniprot id: Q6BZ01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

284592:DEHA2F13838g
gene id: 284592:DEHA2F13838g
uniprot id: Q6BLF6
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

284592:DEHA2G13046g
gene id: 284592:DEHA2G13046g
uniprot id: B5RUR8
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

284592:DEHA2F23738g
gene id: 284592:DEHA2F23738g
uniprot id: Q6BK96
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

284592:DEHA2E02002g
gene id: 284592:DEHA2E02002g
uniprot id: Q6BQV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

284592:DEHA2E16390g
gene id: 284592:DEHA2E16390g
uniprot id: Q6BP56
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S2 family.

284592:DEHA2E04708g
gene id: 284592:DEHA2E04708g
uniprot id: Q6BQJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasm
messages: Serine hydrolase involved in the detoxification of formaldehyde.

284592:DEHA2A08998g
gene id: 284592:DEHA2A08998g
uniprot id: Q6BYJ8
names: Similarity
messages: Belongs to the PET191 family.

284592:DEHA2C15268g
gene id: 284592:DEHA2C15268g
uniprot id: Q6BTX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid transfer protein required for autophagosome completion and peroxisome degradation. Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion. ATG2 binds to the ER exit site (ERES), which is the membrane source for autophagosome formation, using basic residues in its N-terminal region (NR) and to the expanding edge of the IM through its C-terminal region. The latter binding is assisted by an ATG18-PtdIns3P interaction. ATG2 then extracts phospholipids from the membrane source using its NR and transfers them to ATG9 to the IM through its predicted beta-sheet-rich structure for membrane expansion.
messages: Preautophagosomal structure membrane

284592:DEHA2D15554g
gene id: 284592:DEHA2D15554g
uniprot id: B5RTI8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

284592:DEHA2G01870g
gene id: 284592:DEHA2G01870g
uniprot id: Q6BJJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

284592:DEHA2A06182g
gene id: 284592:DEHA2A06182g
uniprot id: B5RSR0
names: Function
names: Similarity
messages: Belongs to the LplA family.
messages: Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.

284592:DEHA2G12056g
gene id: 284592:DEHA2G12056g
uniprot id: Q6BIB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

284592:DEHA2A00440g
gene id: 284592:DEHA2A00440g
uniprot id: Q6BZL6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

284592:DEHA2F09482g
gene id: 284592:DEHA2F09482g
uniprot id: Q6BLZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family.
messages: Cytoplasm
messages: Putative tyrosine-protein phosphatase required for protection against superoxide stress.

284592:DEHA2A14586g
gene id: 284592:DEHA2A14586g
uniprot id: Q6BXV9
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2A13200g
gene id: 284592:DEHA2A13200g
uniprot id: Q6BY16
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

284592:DEHA2A11792g
gene id: 284592:DEHA2A11792g
uniprot id: Q6BY77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the END3 family.
messages: Cell membrane
messages: Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
messages: Component of the PAN1 actin cytoskeleton-regulatory complex.
messages: Endosome membrane
messages: actin patch

284592:DEHA2F21802g
gene id: 284592:DEHA2F21802g
uniprot id: Q6BKI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

284592:DEHA2D10802g
gene id: 284592:DEHA2D10802g
uniprot id: Q6BS85
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284592:DEHA2G18128g
gene id: 284592:DEHA2G18128g
uniprot id: Q6BHJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2C11440g
gene id: 284592:DEHA2C11440g
uniprot id: Q6BUE7
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

284592:DEHA2C00682g
gene id: 284592:DEHA2C00682g
uniprot id: Q6BVQ9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284592:DEHA2G23386g
gene id: 284592:DEHA2G23386g
uniprot id: Q6BGW4
names: Function
messages: Required for stress adaptation, morphogenesis and virulence.

284592:DEHA2F03300g
gene id: 284592:DEHA2F03300g
uniprot id: Q6BMR2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

284592:DEHA2B02288g
gene id: 284592:DEHA2B02288g
uniprot id: Q6BXK3
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

284592:DEHA2G16786g
gene id: 284592:DEHA2G16786g
uniprot id: B5RUU2
names: Subcellular Location Annotation
messages: Mitochondrion outer membrane

284592:DEHA2B01650g
gene id: 284592:DEHA2B01650g
uniprot id: Q6BXN2
names: Similarity
messages: Belongs to the synembryn family.

284592:DEHA2E14608g
gene id: 284592:DEHA2E14608g
uniprot id: Q6BPC9
names: Similarity
messages: Belongs to the MON2 family.

284592:DEHA2B10934g
gene id: 284592:DEHA2B10934g
uniprot id: Q6BWJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSA1 family.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

284592:DEHA2D15092g
gene id: 284592:DEHA2D15092g
uniprot id: Q6BRN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the small ribosomal subunit.
messages: Cytoplasm
messages: Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability.

284592:DEHA2E01518g
gene id: 284592:DEHA2E01518g
uniprot id: Q6BQX6
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

284592:DEHA2F02442g
gene id: 284592:DEHA2F02442g
uniprot id: Q6BMV0
names: Similarity
messages: Belongs to the NAD kinase family.

284592:DEHA2E22858g
gene id: 284592:DEHA2E22858g
uniprot id: Q6BNC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2F19096g
gene id: 284592:DEHA2F19096g
uniprot id: Q6BKU6
names: Similarity
messages: Belongs to the peptidase M18 family.

284592:DEHA2D11418g
gene id: 284592:DEHA2D11418g
uniprot id: B5RTH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAC3 family.
messages: Nucleus envelope

284592:DEHA2D07106g
gene id: 284592:DEHA2D07106g
uniprot id: B5RTE3
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2G22682g
gene id: 284592:DEHA2G22682g
uniprot id: Q6BGY8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

284592:DEHA2F00770g
gene id: 284592:DEHA2F00770g
uniprot id: Q6BN27
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2A00506g
gene id: 284592:DEHA2A00506g
uniprot id: Q6BZL1
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F16654g
gene id: 284592:DEHA2F16654g
uniprot id: Q6BL37
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THI4 family.
messages: Binds 1 Fe cation per subunit.
messages: Cytoplasm
messages: During the catalytic reaction, a sulfide is transferred from Cys-211 to a reaction intermediate, generating a dehydroalanine residue.
messages: Homooctamer.
messages: Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
messages: Nucleus

284592:DEHA2G19932g
gene id: 284592:DEHA2G19932g
uniprot id: Q6BHB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Cytoplasm
messages: Rnase which modulates cell survival under stress conditions. Released from the vacuole to the cytoplasm during stress to promote tRNA and rRNA cleavage and to activate separately a downstream pathway that promotes cell death. Involved in cell size, vacuolar morphology and growth at high temperatures and high salt concentration (By similarity).
messages: Vacuole lumen

284592:DEHA2G16720g
gene id: 284592:DEHA2G16720g
uniprot id: Q6BHQ3
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

284592:DEHA2A02926g
gene id: 284592:DEHA2A02926g
uniprot id: Q6BZ99
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

284592:DEHA2E21318g
gene id: 284592:DEHA2E21318g
uniprot id: B5RU48
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284592:DEHA2E12892g
gene id: 284592:DEHA2E12892g
uniprot id: Q6BPK4
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.
messages: Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P).

284592:DEHA2B00418g
gene id: 284592:DEHA2B00418g
uniprot id: Q6BXT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

284592:DEHA2D03564g
gene id: 284592:DEHA2D03564g
uniprot id: Q6BT47
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

284592:DEHA2A03696g
gene id: 284592:DEHA2A03696g
uniprot id: Q6BZ66
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2A01474g
gene id: 284592:DEHA2A01474g
uniprot id: Q6BZG7
names: Similarity
names: Subunit
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer (By similarity).

284592:DEHA2C10604g
gene id: 284592:DEHA2C10604g
uniprot id: Q6BUH5
names: Similarity
messages: Belongs to the frataxin family.

284592:DEHA2B13200g
gene id: 284592:DEHA2B13200g
uniprot id: B5RSZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

284592:DEHA2E17996g
gene id: 284592:DEHA2E17996g
uniprot id: Q6BNY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BYE1 family.
messages: Negative regulator of transcription elongation.
messages: Nucleus

284592:DEHA2C10142g
gene id: 284592:DEHA2C10142g
uniprot id: Q6BUJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2F25762g
gene id: 284592:DEHA2F25762g
uniprot id: Q6BK12
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

284592:DEHA2G07150g
gene id: 284592:DEHA2G07150g
uniprot id: Q6BIW2
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

284592:DEHA2G22022g
gene id: 284592:DEHA2G22022g
uniprot id: Q6BH20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

284592:DEHA2A06974g
gene id: 284592:DEHA2A06974g
uniprot id: Q6BYU1
names: Similarity
messages: Belongs to the HscB family.

284592:DEHA2G18832g
gene id: 284592:DEHA2G18832g
uniprot id: Q6BHG3
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

284592:DEHA2D06468g
gene id: 284592:DEHA2D06468g
uniprot id: Q6BST1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 28 family.
messages: Endoplasmic reticulum
messages: Heterodimer with ALG14 to form a functional enzyme.
messages: Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway (By similarity).

284592:DEHA2B02618g
gene id: 284592:DEHA2B02618g
uniprot id: Q6BXI7
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

284592:DEHA2E07414g
gene id: 284592:DEHA2E07414g
uniprot id: Q6BQ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

284592:DEHA2G10824g
gene id: 284592:DEHA2G10824g
uniprot id: Q6BIF8
names: Similarity
messages: Belongs to the WD repeat LST8 family.

284592:DEHA2E01298g
gene id: 284592:DEHA2E01298g
uniprot id: Q6BQY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2B12012g
gene id: 284592:DEHA2B12012g
uniprot id: Q6BWE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity).

284592:DEHA2G05918g
gene id: 284592:DEHA2G05918g
uniprot id: Q6BJ17
names: Similarity
messages: Belongs to the asparaginase 1 family.

284592:DEHA2F01012g
gene id: 284592:DEHA2F01012g
uniprot id: Q6BN15
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284592:DEHA2F05258g
gene id: 284592:DEHA2F05258g
uniprot id: Q6BMI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIR3 family.
messages: Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation.
messages: Nucleus

284592:DEHA2D04686g
gene id: 284592:DEHA2D04686g
uniprot id: Q6BT00
names: Function
names: Similarity
messages: Belongs to the CCM1 family.
messages: RNA-binding protein involved in the specific removal of group I introns in mitochondrial encoded transcripts. Maintains the stability of the small subunit mitochondrial 15S rRNA and thus the expression of the mitochondrial genome.

284592:DEHA2D05456g
gene id: 284592:DEHA2D05456g
uniprot id: B5RTR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

284592:DEHA2G24794g
gene id: 284592:DEHA2G24794g
uniprot id: Q6BGQ2
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C07964g
gene id: 284592:DEHA2C07964g
uniprot id: Q6BUU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

284592:DEHA2A00572g
gene id: 284592:DEHA2A00572g
uniprot id: Q6BZK8
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G24882g
gene id: 284592:DEHA2G24882g
uniprot id: Q6BGP7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284592:DEHA2F12342g
gene id: 284592:DEHA2F12342g
uniprot id: B5RUF0
names: Similarity
messages: Belongs to the pyridoxine kinase family.

284592:DEHA2C04070g
gene id: 284592:DEHA2C04070g
uniprot id: Q6BVA8
names: Function
names: Subcellular Location Annotation
messages: May be involved in the mitochondrial lipid metabolism.
messages: Mitochondrion

284592:DEHA2A10362g
gene id: 284592:DEHA2A10362g
uniprot id: Q6BYD7
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2B02816g
gene id: 284592:DEHA2B02816g
uniprot id: B5RT32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2E13530g
gene id: 284592:DEHA2E13530g
uniprot id: B5RU08
names: Similarity
messages: Belongs to the malate synthase family.

284592:DEHA2F17006g
gene id: 284592:DEHA2F17006g
uniprot id: Q6BL21
names: Similarity
messages: Belongs to the WrbA family.

284592:DEHA2G17622g
gene id: 284592:DEHA2G17622g
uniprot id: Q6BHL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM24 family.
messages: Mitochondrion

284592:DEHA2E20460g
gene id: 284592:DEHA2E20460g
uniprot id: Q6BNM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2D18832g
gene id: 284592:DEHA2D18832g
uniprot id: Q6BR66
names: Similarity
messages: Belongs to the PhyH family.

284592:DEHA2C07986g
gene id: 284592:DEHA2C07986g
uniprot id: Q6BUU2
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

284592:DEHA2F00396g
gene id: 284592:DEHA2F00396g
uniprot id: Q6BN42
names: Similarity
messages: Belongs to the MSOX/MTOX family.

284592:DEHA2E16126g
gene id: 284592:DEHA2E16126g
uniprot id: Q6BP66
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2F04246g
gene id: 284592:DEHA2F04246g
uniprot id: Q6BMM0
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

284592:DEHA2C05808g
gene id: 284592:DEHA2C05808g
uniprot id: Q6BV30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
messages: Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro. Required for respiration and the maintenance of the mitochondrial compartment.
messages: Homodimer.
messages: Mitochondrion matrix

284592:DEHA2B05896g
gene id: 284592:DEHA2B05896g
uniprot id: Q6BX52
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

284592:DEHA2F19470g
gene id: 284592:DEHA2F19470g
uniprot id: Q6BKS8
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

284592:DEHA2A10098g
gene id: 284592:DEHA2A10098g
uniprot id: Q6BYE9
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

284592:DEHA2F05566g
gene id: 284592:DEHA2F05566g
uniprot id: Q6BMG8
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F12540g
gene id: 284592:DEHA2F12540g
uniprot id: Q6BLL4
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

284592:DEHA2A07810g
gene id: 284592:DEHA2A07810g
uniprot id: Q6BYP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SQS1 family.
messages: Cytoplasm
messages: May be involved in splicing.
messages: Nucleus

284592:DEHA2D10780g
gene id: 284592:DEHA2D10780g
uniprot id: Q6BS86
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.

284592:DEHA2E16742g
gene id: 284592:DEHA2E16742g
uniprot id: Q6BP40
names: Similarity
messages: Belongs to the RecA family. DMC1 subfamily.

284592:DEHA2A08712g
gene id: 284592:DEHA2A08712g
uniprot id: Q6BYL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

284592:DEHA2G12650g
gene id: 284592:DEHA2G12650g
uniprot id: Q6BI86
names: Similarity
messages: Belongs to the SUN family.

284592:DEHA2B02596g
gene id: 284592:DEHA2B02596g
uniprot id: Q6BXI8
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

284592:DEHA2E01408g
gene id: 284592:DEHA2E01408g
uniprot id: Q6BQY2
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F24816g
gene id: 284592:DEHA2F24816g
uniprot id: Q6BK53
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

284592:DEHA2C02662g
gene id: 284592:DEHA2C02662g
uniprot id: Q6BVH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

284592:DEHA2G10384g
gene id: 284592:DEHA2G10384g
uniprot id: Q6BIH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

284592:DEHA2D04268g
gene id: 284592:DEHA2D04268g
uniprot id: Q6BT18
names: Similarity
messages: Belongs to the lipin family.

284592:DEHA2E20658g
gene id: 284592:DEHA2E20658g
uniprot id: Q6BNM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

284592:DEHA2G09592g
gene id: 284592:DEHA2G09592g
uniprot id: Q6BIK8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

284592:DEHA2D08536g
gene id: 284592:DEHA2D08536g
uniprot id: Q6BSI8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

284592:DEHA2E11000g
gene id: 284592:DEHA2E11000g
uniprot id: Q6BPT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

284592:DEHA2G22352g
gene id: 284592:DEHA2G22352g
uniprot id: Q6BH05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 5 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284592:DEHA2F11572g
gene id: 284592:DEHA2F11572g
uniprot id: Q6BLQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

284592:DEHA2A05170g
gene id: 284592:DEHA2A05170g
uniprot id: Q6BZ23
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

284592:DEHA2B03366g
gene id: 284592:DEHA2B03366g
uniprot id: Q6BXF8
names: Similarity
messages: Belongs to the SAS10 family.

284592:DEHA2C08668g
gene id: 284592:DEHA2C08668g
uniprot id: Q6BUR4
names: Similarity
messages: Belongs to the APC5 family.

284592:DEHA2A05808g
gene id: 284592:DEHA2A05808g
uniprot id: Q6BYZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

284592:DEHA2C13508g
gene id: 284592:DEHA2C13508g
uniprot id: B5RTB1
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

284592:DEHA2C08074g
gene id: 284592:DEHA2C08074g
uniprot id: Q6BUT8
names: Similarity
messages: Belongs to the peptidase A1 family.

284592:DEHA2B15070g
gene id: 284592:DEHA2B15070g
uniprot id: Q6BW16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Membrane
messages: Mitochondrion outer membrane

284592:DEHA2G13772g
gene id: 284592:DEHA2G13772g
uniprot id: Q6BI33
names: Similarity
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.

284592:DEHA2F02552g
gene id: 284592:DEHA2F02552g
uniprot id: Q6BMU5
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

284592:DEHA2D05742g
gene id: 284592:DEHA2D05742g
uniprot id: Q6BSV4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

284592:DEHA2F16786g
gene id: 284592:DEHA2F16786g
uniprot id: B5RUI2
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

284592:DEHA2B15488g
gene id: 284592:DEHA2B15488g
uniprot id: Q6BVZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

284592:DEHA2F10560g
gene id: 284592:DEHA2F10560g
uniprot id: Q6BLU8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the RRM CWC2 family.
messages: Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle (By similarity).
messages: Nucleus
messages: The C-terminal RRM domain and the zinc finger motif are necessary for RNA-binding.

284592:DEHA2G18326g
gene id: 284592:DEHA2G18326g
uniprot id: Q6BHI4
names: Similarity
messages: Belongs to the peptidase M20A family.

284592:DEHA2D01628g
gene id: 284592:DEHA2D01628g
uniprot id: Q6BTD1
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D17160g
gene id: 284592:DEHA2D17160g
uniprot id: Q6BRD9
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

284592:DEHA2E16302g
gene id: 284592:DEHA2E16302g
uniprot id: Q6BP60
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2A05610g
gene id: 284592:DEHA2A05610g
uniprot id: Q6BZ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284592:DEHA2C16258g
gene id: 284592:DEHA2C16258g
uniprot id: Q6BTS5
names: Similarity
messages: Belongs to the TACO1 family.

284592:DEHA2F19052g
gene id: 284592:DEHA2F19052g
uniprot id: Q6BKU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CUE1 family.
messages: Component of the endoplasmic reticulum-associated protein degradation (ERAD) pathway. Recruits the soluble ubiquitin-conjugating enzyme UBC7 to the cytoplasmic face of the endoplasmic reticulum membrane where it functions in degradation of misfolded or regulated proteins localized in the endoplasmic reticulum (ER) lumen or membrane via the ubiquitin-proteasome system. Targets the E2 conjugating enzyme UBC7 to the DOA10 ubiquitin ligase complex, which is part of the ERAD-C pathway responsible for the rapid degradation of membrane proteins with misfolded cytoplasmic domains, and to the HRD1 ubiquitin ligase complex, which is part of the ERAD-L and ERAD-M pathways responsible for the rapid degradation of soluble lumenal and membrane proteins with misfolded lumenal domains (ERAD-L), or ER-membrane proteins with misfolded transmembrane domains (ERAD-M) (By similarity).
messages: Endoplasmic reticulum membrane
messages: Forms a heterodimer with UBC7.

284592:DEHA2G05126g
gene id: 284592:DEHA2G05126g
uniprot id: Q6BJ52
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

284592:DEHA2D05610g
gene id: 284592:DEHA2D05610g
uniprot id: Q6BSV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

284592:DEHA2G07898g
gene id: 284592:DEHA2G07898g
uniprot id: Q6BIT0
names: Similarity
messages: Belongs to the guanylate kinase family.

284592:DEHA2B02464g
gene id: 284592:DEHA2B02464g
uniprot id: Q6BXJ4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM1 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code.
messages: Nucleus
messages: The JmjC domain mediates the demethylation activity.

284592:DEHA2D12078g
gene id: 284592:DEHA2D12078g
uniprot id: Q6BS26
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E05478g
gene id: 284592:DEHA2E05478g
uniprot id: Q6BQG3
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

284592:DEHA2A12672g
gene id: 284592:DEHA2A12672g
uniprot id: Q6BY39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.

284592:DEHA2C13002g
gene id: 284592:DEHA2C13002g
uniprot id: Q6BU78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Involved in the regulation of telomere length, clustering and has a specific role in telomere position effect (TPE).
messages: Nucleus
messages: telomere

284592:DEHA2B00396g
gene id: 284592:DEHA2B00396g
uniprot id: Q6BXT5
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G11748g
gene id: 284592:DEHA2G11748g
uniprot id: Q6BID3
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

284592:DEHA2D16038g
gene id: 284592:DEHA2D16038g
uniprot id: Q6BRI8
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284592:DEHA2E12650g
gene id: 284592:DEHA2E12650g
uniprot id: B5RU00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

284592:DEHA2D11924g
gene id: 284592:DEHA2D11924g
uniprot id: B5RTH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2C03388g
gene id: 284592:DEHA2C03388g
uniprot id: Q6BVD9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

284592:DEHA2A10538g
gene id: 284592:DEHA2A10538g
uniprot id: Q6BRZ5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation of histone H3 leads to transcriptional activation. H3K14ac formation by GCN5 is promoted by H3S10ph. H3K14ac can also be formed by ESA1. H3K56ac formation occurs predominantly in newly synthesized H3 molecules during G1, S and G2/M of the cell cycle and may be involved in DNA repair (By similarity).
messages: Belongs to the histone H3 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).
messages: Mono-, di- and trimethylated by the COMPASS complex to form H3K4me1/2/3. H3K4me activates gene expression by regulating transcription elongation and plays a role in telomere length maintenance. H3K4me enrichment correlates with transcription levels, and occurs in a 5' to 3' gradient with H3K4me3 enrichment at the 5'-end of genes, shifting to H3K4me2 and then H3K4me1. Methylated by SET2 to form H3K36me. H3K36me represses gene expression. Methylated by DOT1 to form H3K79me. H3K79me is required for association of SIR proteins with telomeric regions and for telomeric silencing. The COMPASS-mediated formation of H3K4me2/3 and the DOT1-mediated formation of H3K79me require H2BK123ub1 (By similarity).
messages: Nucleus
messages: Phosphorylated by IPL1 to form H3S10ph. H3S10ph promotes subsequent H3K14ac formation by GCN5 and is required for transcriptional activation through TBP recruitment to the promoters (By similarity).
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA (By similarity).
messages: To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H3K4me1/2/3 = mono-, di- and trimethylated Lys-5; H3K9ac = acetylated Lys-10; H3K9me1 = monomethylated Lys-10; H3S10ph = phosphorylated Ser-11; H3K14ac = acetylated Lys-15; H3K14me2 = dimethylated Lys-15; H3K18ac = acetylated Lys-19; H3K18me1 = monomethylated Lys-19; H3K23ac = acetylated Lys-24; H3K23me1 = monomethylated Lys-24; H3K27ac = acetylated Lys-28; H3K27me1/2/3 = mono-, di- and trimethylated Lys-28; H3K36ac = acetylated Lys-37; H3K36me1/2/3 = mono-, di- and trimethylated Lys-37; H3K56ac = acetylated Lys-57; H3K64ac = acetylated Lys-65; H3K79me1/2/3 = mono-, di- and trimethylated Lys-80.

284592:DEHA2F17204g
gene id: 284592:DEHA2F17204g
uniprot id: Q6BL12
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

284592:DEHA2G04202g
gene id: 284592:DEHA2G04202g
uniprot id: Q6BJ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2F24574g
gene id: 284592:DEHA2F24574g
uniprot id: Q6BK62
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

284592:DEHA2C12254g
gene id: 284592:DEHA2C12254g
uniprot id: B5RTA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.
messages: Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5.
messages: Nucleus

284592:DEHA2C03476g
gene id: 284592:DEHA2C03476g
uniprot id: Q6BVD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNN1/MNT family.
messages: Golgi apparatus membrane
messages: Membrane

284592:DEHA2G16214g
gene id: 284592:DEHA2G16214g
uniprot id: Q6BHS1
names: Similarity
messages: Belongs to the peptidase M16 family.

284592:DEHA2D14806g
gene id: 284592:DEHA2D14806g
uniprot id: Q6BRP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM9 family.
messages: Mitochondrion

284592:DEHA2G20306g
gene id: 284592:DEHA2G20306g
uniprot id: Q6BH96
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

284592:DEHA2F01364g
gene id: 284592:DEHA2F01364g
uniprot id: Q6BMZ8
names: Similarity
messages: Belongs to the PdxS/SNZ family.

284592:DEHA2E16170g
gene id: 284592:DEHA2E16170g
uniprot id: Q6BP65
names: Function
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.

284592:DEHA2F04664g
gene id: 284592:DEHA2F04664g
uniprot id: B5RU96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

284592:DEHA2A12804g
gene id: 284592:DEHA2A12804g
uniprot id: Q6BY34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

284592:DEHA2A12936g
gene id: 284592:DEHA2A12936g
uniprot id: Q6BY28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
messages: Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
messages: Endoplasmic reticulum membrane

284592:DEHA2C16830g
gene id: 284592:DEHA2C16830g
uniprot id: Q6BTP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Component of the PAM complex, at least composed of mtHsp70, MGE1, TIM44, PAM16, PAM17 and PAM18.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of SSC1 to substrate proteins (By similarity).
messages: Mitochondrion matrix

284592:DEHA2C13156g
gene id: 284592:DEHA2C13156g
uniprot id: B5RTA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 16 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

284592:DEHA2A04532g
gene id: 284592:DEHA2A04532g
uniprot id: Q6BZ50
names: Similarity
messages: Belongs to the bystin family.

284592:DEHA2F25388g
gene id: 284592:DEHA2F25388g
uniprot id: Q6BK27
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

284592:DEHA2F02134g
gene id: 284592:DEHA2F02134g
uniprot id: Q6BMW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
messages: Nucleus

284592:DEHA2G09262g
gene id: 284592:DEHA2G09262g
uniprot id: Q6BIM1
names: Similarity
messages: Belongs to the MGR2 family.

284592:DEHA2A07106g
gene id: 284592:DEHA2A07106g
uniprot id: Q6BYT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus

284592:DEHA2C16764g
gene id: 284592:DEHA2C16764g
uniprot id: Q6BTQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

284592:DEHA2F23782g
gene id: 284592:DEHA2F23782g
uniprot id: Q6BK94
names: Similarity
messages: Belongs to the protein kinase superfamily.

284592:DEHA2F05126g
gene id: 284592:DEHA2F05126g
uniprot id: Q6BMI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

284592:DEHA2F22242g
gene id: 284592:DEHA2F22242g
uniprot id: Q6BKG1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uL10 forms part of the P stalk that participates in recruiting G proteins to the ribosome.

284592:DEHA2E12804g
gene id: 284592:DEHA2E12804g
uniprot id: Q6BPK7
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

284592:DEHA2C02882g
gene id: 284592:DEHA2C02882g
uniprot id: Q6BVG4
names: Similarity
messages: Belongs to the AB hydrolase superfamily. MetX family.

284592:DEHA2F18832g
gene id: 284592:DEHA2F18832g
uniprot id: Q6BKV7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

284592:DEHA2D17028g
gene id: 284592:DEHA2D17028g
uniprot id: Q6BRE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol (By similarity).
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane

284592:DEHA2G04620g
gene id: 284592:DEHA2G04620g
uniprot id: Q6BJ75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNO1 family.
messages: Component of the small ribosomal subunit, ribosomal RNA processing complex (SSU RRP complex).
messages: Cytoplasm
messages: Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species (By similarity).
messages: nucleolus

284592:DEHA2G12210g
gene id: 284592:DEHA2G12210g
uniprot id: Q6BIA9
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

284592:DEHA2A04576g
gene id: 284592:DEHA2A04576g
uniprot id: Q6BZ48
names: Similarity
messages: Belongs to the CNOT9 family.

284592:DEHA2G21604g
gene id: 284592:DEHA2G21604g
uniprot id: Q6BH39
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

284592:DEHA2F07678g
gene id: 284592:DEHA2F07678g
uniprot id: B5RUB6
names: Similarity
messages: Belongs to the NEMF family.

284592:DEHA2D11022g
gene id: 284592:DEHA2D11022g
uniprot id: Q6BS76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

284592:DEHA2F24464g
gene id: 284592:DEHA2F24464g
uniprot id: Q6BK67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284592:DEHA2G04136g
gene id: 284592:DEHA2G04136g
uniprot id: Q6BJ95
names: Similarity
messages: Belongs to the AAA ATPase family.

284592:DEHA2A05434g
gene id: 284592:DEHA2A05434g
uniprot id: Q6BZ11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

284592:DEHA2G10912g
gene id: 284592:DEHA2G10912g
uniprot id: Q6BIF4
names: Similarity
messages: Belongs to the DCC1 family.

284592:DEHA2B14740g
gene id: 284592:DEHA2B14740g
uniprot id: Q6BW31
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E18216g
gene id: 284592:DEHA2E18216g
uniprot id: Q6BNX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pseudouridine synthase RluA family.
messages: Mitochondrion
messages: Pseudouridylate synthase responsible for the pseudouridine-2819 formation in mitochondrial 21S rRNA. May modulate the efficiency or the fidelity of the mitochondrial translation machinery.

284592:DEHA2D11594g
gene id: 284592:DEHA2D11594g
uniprot id: Q6BS49
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2F10252g
gene id: 284592:DEHA2F10252g
uniprot id: Q6BLW1
names: Similarity
messages: Belongs to the thymidylate kinase family.

284592:DEHA2D12298g
gene id: 284592:DEHA2D12298g
uniprot id: Q6BS15
names: Function
names: Similarity
messages: Belongs to the MOZART1 family.
messages: Required for gamma-tubulin complex recruitment to the microtubule organizing center (MTOC).

284592:DEHA2D01386g
gene id: 284592:DEHA2D01386g
uniprot id: Q6BTE2
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

284592:DEHA2D03872g
gene id: 284592:DEHA2D03872g
uniprot id: Q6BT35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex, whose core is composed of TIM22 and TIM54, associated with the 70 kDa heterohexamer composed of TIM9 and TIM10 (or TIM8 and TIM13).
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
messages: Mitochondrion inner membrane

284592:DEHA2F15818g
gene id: 284592:DEHA2F15818g
uniprot id: Q6BL74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

284592:DEHA2G16830g
gene id: 284592:DEHA2G16830g
uniprot id: Q6BHP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of a fungal signal recognition particle (SRP) complex that consists of a 7SL RNA molecule (scR1) and at least six protein subunits: SRP72, SRP68, SRP54, SEC65, SRP21 and SRP14.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

284592:DEHA2G22792g
gene id: 284592:DEHA2G22792g
uniprot id: B5RUY4
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

284592:DEHA2C12738g
gene id: 284592:DEHA2C12738g
uniprot id: Q6BU90
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

284592:DEHA2C16874g
gene id: 284592:DEHA2C16874g
uniprot id: Q6BTP7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

284592:DEHA2G08646g
gene id: 284592:DEHA2G08646g
uniprot id: Q6BIP8
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

284592:DEHA2G04114g
gene id: 284592:DEHA2G04114g
uniprot id: Q6BJ96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Alpha-1,2-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers a fourth mannose to trimannosyl-GPIs during GPI precursor assembly. The presence of a fourth mannose in GPI is essential in fungi (By similarity).
messages: Belongs to the glycosyltransferase 22 family. PIGZ subfamily.
messages: Endoplasmic reticulum membrane

284592:DEHA2D01342g
gene id: 284592:DEHA2D01342g
uniprot id: Q6BTE4
names: Similarity
messages: Belongs to the FMO family.

284592:DEHA2G21428g
gene id: 284592:DEHA2G21428g
uniprot id: Q6BH47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP5 family.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2F17996g
gene id: 284592:DEHA2F17996g
uniprot id: Q6BKY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

284592:DEHA2C08228g
gene id: 284592:DEHA2C08228g
uniprot id: B5RT90
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F17886g
gene id: 284592:DEHA2F17886g
uniprot id: Q6BKY3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284592:DEHA2G11176g
gene id: 284592:DEHA2G11176g
uniprot id: Q6BIE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL27 family.
messages: Component of the large subunit of mitochondrial ribosome.
messages: Mitochondrion

284592:DEHA2G06248g
gene id: 284592:DEHA2G06248g
uniprot id: Q6BJ02
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2D08514g
gene id: 284592:DEHA2D08514g
uniprot id: Q6BSI9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

284592:DEHA2C14234g
gene id: 284592:DEHA2C14234g
uniprot id: Q6BU19
names: Subcellular Location Annotation
messages: Nucleus membrane

284592:DEHA2F19998g
gene id: 284592:DEHA2F19998g
uniprot id: Q6BKQ6
names: Similarity
messages: Belongs to the peptidase M24B family.

284592:DEHA2F05302g
gene id: 284592:DEHA2F05302g
uniprot id: B5RUA2
names: Similarity
messages: Belongs to the XPC family.

284592:DEHA2D18766g
gene id: 284592:DEHA2D18766g
uniprot id: B5RTM8
names: Similarity
messages: Belongs to the peptidase C19 family.

284592:DEHA2G05852g
gene id: 284592:DEHA2G05852g
uniprot id: Q6BJ20
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

284592:DEHA2E02200g
gene id: 284592:DEHA2E02200g
uniprot id: Q6BQU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2E22748g
gene id: 284592:DEHA2E22748g
uniprot id: Q6BND1
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

284592:DEHA2A10340g
gene id: 284592:DEHA2A10340g
uniprot id: Q6BYD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Membrane

284592:DEHA2E10956g
gene id: 284592:DEHA2E10956g
uniprot id: Q6BPT6
names: Similarity
messages: Belongs to the AIM32 family.

284592:DEHA2B10318g
gene id: 284592:DEHA2B10318g
uniprot id: Q6BWL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRE9/KNH1 family.
messages: Involved in cell wall beta(1->6) glucan synthesis.
messages: cell wall

284592:DEHA2G23254g
gene id: 284592:DEHA2G23254g
uniprot id: Q6BGW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB2 family.
messages: Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

284592:DEHA2E24332g
gene id: 284592:DEHA2E24332g
uniprot id: Q6BN61
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

284592:DEHA2F10538g
gene id: 284592:DEHA2F10538g
uniprot id: Q6BLU9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).
messages: Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.
messages: Component of the U5 snRNP complex.
messages: Cytoplasm
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284592:DEHA2C01584g
gene id: 284592:DEHA2C01584g
uniprot id: Q6BVL8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

284592:DEHA2B03124g
gene id: 284592:DEHA2B03124g
uniprot id: Q6BXG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM3 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.

284592:DEHA2F20812g
gene id: 284592:DEHA2F20812g
uniprot id: Q6BKL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mitochondrion inner membrane

284592:DEHA2D02376g
gene id: 284592:DEHA2D02376g
uniprot id: Q6BMN8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

284592:DEHA2A02332g
gene id: 284592:DEHA2A02332g
uniprot id: Q6BZC9
names: Similarity
messages: Belongs to the DCP1 family.

284592:DEHA2D17072g
gene id: 284592:DEHA2D17072g
uniprot id: Q6BRE4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. May also be involved in early transcription (By similarity).
messages: Associates with the nuclear pore complex.
messages: Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
messages: Cytoplasm
messages: Nucleus membrane
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nuclear pore complex

284592:DEHA2D16522g
gene id: 284592:DEHA2D16522g
uniprot id: Q6BRG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. The complex is held together by ERB1, which interacts with NOP7 via its N-terminal domain and with YTM1 via a high-affinity interaction between the seven-bladed beta-propeller domains of the 2 proteins. The NOP7 complex associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

284592:DEHA2F25806g
gene id: 284592:DEHA2F25806g
uniprot id: Q6BK10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

284592:DEHA2D08558g
gene id: 284592:DEHA2D08558g
uniprot id: Q6BSI7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

284592:DEHA2A09988g
gene id: 284592:DEHA2A09988g
uniprot id: Q6BYF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.

284592:DEHA2C07634g
gene id: 284592:DEHA2C07634g
uniprot id: Q6BUV6
names: Similarity
messages: Belongs to the AAA ATPase family.

284592:DEHA2C10340g
gene id: 284592:DEHA2C10340g
uniprot id: Q6BUI7
names: Subcellular Location Annotation
messages: telomere

284592:DEHA2B12386g
gene id: 284592:DEHA2B12386g
uniprot id: Q6BWC6
names: Similarity
messages: Belongs to the protein kinase superfamily.

284592:DEHA2E15026g
gene id: 284592:DEHA2E15026g
uniprot id: Q6BPB2
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C03850g
gene id: 284592:DEHA2C03850g
uniprot id: Q6BVC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

284592:DEHA2G05786g
gene id: 284592:DEHA2G05786g
uniprot id: Q6BJ24
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

284592:DEHA2A00836g
gene id: 284592:DEHA2A00836g
uniprot id: Q6BZJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride exporter Fluc/FEX family.
messages: Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
messages: Membrane

284592:DEHA2G00748g
gene id: 284592:DEHA2G00748g
uniprot id: Q6BJQ5
names: Similarity
messages: Belongs to the arginase family.

284592:DEHA2G24376g
gene id: 284592:DEHA2G24376g
uniprot id: Q6BGS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPS2 family.
messages: Cell membrane
messages: Membrane

284592:DEHA2G08206g
gene id: 284592:DEHA2G08206g
uniprot id: Q6BIR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

284592:DEHA2F16148g
gene id: 284592:DEHA2F16148g
uniprot id: Q6BL60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Mitochondrion inner membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

284592:DEHA2D16324g
gene id: 284592:DEHA2D16324g
uniprot id: Q6BRH5
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

284592:DEHA2A08492g
gene id: 284592:DEHA2A08492g
uniprot id: Q6BYM2
names: Similarity
messages: Belongs to the EIS1 family.

284592:DEHA2D14080g
gene id: 284592:DEHA2D14080g
uniprot id: Q6BRT0
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

284592:DEHA2E01232g
gene id: 284592:DEHA2E01232g
uniprot id: Q6BQZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homotetramer.
messages: Mitochondrion matrix

284592:DEHA2C03322g
gene id: 284592:DEHA2C03322g
uniprot id: Q6BVE2
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

284592:DEHA2F06644g
gene id: 284592:DEHA2F06644g
uniprot id: Q6BMC3
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C11462g
gene id: 284592:DEHA2C11462g
uniprot id: Q6BUE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that trimethylates elongation factor 1-alpha at 'Lys-79'.

284592:DEHA2F15136g
gene id: 284592:DEHA2F15136g
uniprot id: Q6BLA3
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

284592:DEHA2G15004g
gene id: 284592:DEHA2G15004g
uniprot id: Q6BHX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.

284592:DEHA2F14960g
gene id: 284592:DEHA2F14960g
uniprot id: Q6BLB1
names: Similarity
messages: Belongs to the PurH family.

284592:DEHA2E20174g
gene id: 284592:DEHA2E20174g
uniprot id: Q6BNN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation), facilitation of DNA opening and initiation of transcription. SAGA is required for recruitment of the basal transcription machinery. SLIK is proposed to have partly overlapping functions with SAGA.
messages: Nucleus

284592:DEHA2A04422g
gene id: 284592:DEHA2A04422g
uniprot id: Q6BZ55
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D07238g
gene id: 284592:DEHA2D07238g
uniprot id: Q6BSP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns (By similarity).
messages: Nucleus

284592:DEHA2G08822g
gene id: 284592:DEHA2G08822g
uniprot id: Q6BIP1
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

284592:DEHA2G18920g
gene id: 284592:DEHA2G18920g
uniprot id: Q6BHF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

284592:DEHA2C00770g
gene id: 284592:DEHA2C00770g
uniprot id: Q6BVQ5
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E12848g
gene id: 284592:DEHA2E12848g
uniprot id: Q6BPK5
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2A03608g
gene id: 284592:DEHA2A03608g
uniprot id: Q6BZ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

284592:DEHA2B00946g
gene id: 284592:DEHA2B00946g
uniprot id: Q6BXR0
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.

284592:DEHA2F18810g
gene id: 284592:DEHA2F18810g
uniprot id: Q6BKV8
names: Subcellular Location Annotation
messages: nuclear pore complex

284592:DEHA2G03080g
gene id: 284592:DEHA2G03080g
uniprot id: Q6BJE2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in nonsense-mediated decay of mRNAs containing premature stop codons.

284592:DEHA2D07458g
gene id: 284592:DEHA2D07458g
uniprot id: B5RTF0
names: Similarity
messages: Belongs to the BMT family.

284592:DEHA2F27016g
gene id: 284592:DEHA2F27016g
uniprot id: Q6BJV8
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G12320g
gene id: 284592:DEHA2G12320g
uniprot id: Q6BIA3
names: Similarity
messages: Belongs to the actin family.

284592:DEHA2F06446g
gene id: 284592:DEHA2F06446g
uniprot id: B5RUA6
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2F05808g
gene id: 284592:DEHA2F05808g
uniprot id: Q6BMF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM3 family.
messages: Membrane raft

284592:DEHA2G08140g
gene id: 284592:DEHA2G08140g
uniprot id: Q6BIR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Cytoplasm
messages: Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.
messages: Interacts with NAR1.
messages: Nucleus

284592:DEHA2A08844g
gene id: 284592:DEHA2A08844g
uniprot id: B5RST3
names: Similarity
messages: Belongs to the VPS8 family.

284592:DEHA2G20966g
gene id: 284592:DEHA2G20966g
uniprot id: Q6BH67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2B02068g
gene id: 284592:DEHA2B02068g
uniprot id: Q6BXL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

284592:DEHA2D15444g
gene id: 284592:DEHA2D15444g
uniprot id: Q6BRL6
names: Similarity
messages: Belongs to the cullin family.

284592:DEHA2A03212g
gene id: 284592:DEHA2A03212g
uniprot id: Q6BZ86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.

284592:DEHA2G13090g
gene id: 284592:DEHA2G13090g
uniprot id: Q6BI64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

284592:DEHA2A13288g
gene id: 284592:DEHA2A13288g
uniprot id: Q6BY12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

284592:DEHA2B06380g
gene id: 284592:DEHA2B06380g
uniprot id: Q6BX32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Heterotetramer; composed of two copies of TRM6 and two copies of TRM61.
messages: Nucleus

284592:DEHA2C02574g
gene id: 284592:DEHA2C02574g
uniprot id: Q6BVH8
names: Similarity
messages: Belongs to the MYG1 family.

284592:DEHA2F12298g
gene id: 284592:DEHA2F12298g
uniprot id: Q6BLM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAD18 family.
messages: E3 RING-finger protein, member of the UBC2/RAD6 epistasis group. Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA.
messages: Interacts with E2 UBC2, forming a complex with ubiquitin ligase activity.
messages: Nucleus

284592:DEHA2F01606g
gene id: 284592:DEHA2F01606g
uniprot id: Q6BMY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

284592:DEHA2E13838g
gene id: 284592:DEHA2E13838g
uniprot id: Q6BPG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

284592:DEHA2F24640g
gene id: 284592:DEHA2F24640g
uniprot id: Q6BK59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
messages: Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization.
messages: Endoplasmic reticulum membrane

284592:DEHA2A08756g
gene id: 284592:DEHA2A08756g
uniprot id: Q6BYL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

284592:DEHA2E22352g
gene id: 284592:DEHA2E22352g
uniprot id: B5RU57
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E24310g
gene id: 284592:DEHA2E24310g
uniprot id: Q6BN62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2B15246g
gene id: 284592:DEHA2B15246g
uniprot id: Q6BW07
names: Function
names: Similarity
messages: Belongs to the RRT5 family.
messages: May be involved in the modulation of rDNA transcription.

284592:DEHA2G01254g
gene id: 284592:DEHA2G01254g
uniprot id: B5RV11
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

284592:DEHA2A07260g
gene id: 284592:DEHA2A07260g
uniprot id: Q6BYS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2E14718g
gene id: 284592:DEHA2E14718g
uniprot id: Q6BPC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.

284592:DEHA2D17820g
gene id: 284592:DEHA2D17820g
uniprot id: B5RTK5
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

284592:DEHA2E13442g
gene id: 284592:DEHA2E13442g
uniprot id: Q6BPI1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.
messages: The active site is a redox-active disulfide bond.

284592:DEHA2E20526g
gene id: 284592:DEHA2E20526g
uniprot id: Q6BNM6
names: Similarity
messages: Belongs to the PP2C family.

284592:DEHA2A04774g
gene id: 284592:DEHA2A04774g
uniprot id: Q6BZ40
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

284592:DEHA2F00594g
gene id: 284592:DEHA2F00594g
uniprot id: B5RU76
names: Similarity
messages: Belongs to the peptidase M20A family.

284592:DEHA2G17644g
gene id: 284592:DEHA2G17644g
uniprot id: Q6BHL6
names: Similarity
messages: Belongs to the XPG/RAD2 endonuclease family.

284592:DEHA2A12144g
gene id: 284592:DEHA2A12144g
uniprot id: Q6BY61
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284592:DEHA2G07942g
gene id: 284592:DEHA2G07942g
uniprot id: Q6BIS8
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOS6 family.
messages: Membrane
messages: The GPI-anchor is attached to the protein in the endoplasmic reticulum and serves to target the protein to the cell surface. There, the glucosamine-inositol phospholipid moiety is cleaved off and the GPI-modified mannoprotein is covalently attached via its lipidless GPI glycan remnant to the 1,6-beta-glucan of the outer cell wall layer (By similarity).
messages: cell wall

284592:DEHA2E07502g
gene id: 284592:DEHA2E07502g
uniprot id: Q6BQ83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL67 family.
messages: Mitochondrion
messages: Nucleus
messages: Transcription factor involved in regulation of RNA polymerase II-dependent transcription. Also involved in regulation of mitochondrial DNA recombination, maintenance and repair, and generation of homoplasmic cells (By similarity).

284592:DEHA2F01870g
gene id: 284592:DEHA2F01870g
uniprot id: Q6BMX5
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

284592:DEHA2F04356g
gene id: 284592:DEHA2F04356g
uniprot id: Q6BML6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

284592:DEHA2E15378g
gene id: 284592:DEHA2E15378g
uniprot id: Q6BP96
names: Function
names: Subcellular Location Annotation
messages: Acts as component of the general transcription and DNA repair factor IIH (TFIIH or factor B), which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. TFIIH as CTD kinase activity and DNA-dependent ATPase activity, and is essential for polymerase II transcription (By similarity).
messages: Nucleus

284592:DEHA2B16610g
gene id: 284592:DEHA2B16610g
uniprot id: B5RSX2
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G02222g
gene id: 284592:DEHA2G02222g
uniprot id: Q6BJI2
names: Function
messages: Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).

284592:DEHA2D04312g
gene id: 284592:DEHA2D04312g
uniprot id: Q6BT15
names: Similarity
messages: Belongs to the BMT family.

284592:DEHA2F13464g
gene id: 284592:DEHA2F13464g
uniprot id: Q6BLH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

284592:DEHA2G09548g
gene id: 284592:DEHA2G09548g
uniprot id: Q6BIL0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284592:DEHA2D12452g
gene id: 284592:DEHA2D12452g
uniprot id: Q6BS08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a ternary complex with ATG13 and ATG17.
messages: Preautophagosomal structure membrane
messages: Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates. Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9. Catalyzes phosphorylation of ATG4, decreasing the interaction between ATG4 and ATG8 and impairing deconjugation of PE-conjugated forms of ATG8.

284592:DEHA2G23870g
gene id: 284592:DEHA2G23870g
uniprot id: Q6BGU4
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

284592:DEHA2B14718g
gene id: 284592:DEHA2B14718g
uniprot id: Q6BW32
names: Similarity
messages: Belongs to the alkaline phosphatase family.

284592:DEHA2F23474g
gene id: 284592:DEHA2F23474g
uniprot id: Q6BKA8
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

284592:DEHA2F09284g
gene id: 284592:DEHA2F09284g
uniprot id: Q6BM07
names: Similarity
messages: Belongs to the protein kinase superfamily.

284592:DEHA2B15554g
gene id: 284592:DEHA2B15554g
uniprot id: Q6BVZ3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle (By similarity).

284592:DEHA2G07876g
gene id: 284592:DEHA2G07876g
uniprot id: Q6BIT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the respiratory chain complex III/complex IV supercomplex.
messages: Belongs to the RCF1 family.
messages: Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
messages: Mitochondrion membrane

284592:DEHA2F09570g
gene id: 284592:DEHA2F09570g
uniprot id: Q6BLZ4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Mitochondrion

284592:DEHA2F07172g
gene id: 284592:DEHA2F07172g
uniprot id: B5RUB1
names: Similarity
messages: Belongs to the CAND family.

284592:DEHA2B05874g
gene id: 284592:DEHA2B05874g
uniprot id: Q6BX53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

284592:DEHA2G22110g
gene id: 284592:DEHA2G22110g
uniprot id: Q6BH16
names: Similarity
messages: Belongs to the ELP6 family.

284592:DEHA2C02222g
gene id: 284592:DEHA2C02222g
uniprot id: Q6BVJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

284592:DEHA2C09724g
gene id: 284592:DEHA2C09724g
uniprot id: Q6BUL2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

284592:DEHA2A02904g
gene id: 284592:DEHA2A02904g
uniprot id: Q6BZA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
messages: Mitochondrion membrane

284592:DEHA2D18084g
gene id: 284592:DEHA2D18084g
uniprot id: B5RTL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex ASK1 family.
messages: Nucleus
messages: kinetochore
messages: spindle

284592:DEHA2E18326g
gene id: 284592:DEHA2E18326g
uniprot id: Q6BNX3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

284592:DEHA2C12122g
gene id: 284592:DEHA2C12122g
uniprot id: Q6BUB6
names: Similarity
messages: Belongs to the diacylglycerol acyltransferase family.

284592:DEHA2B14916g
gene id: 284592:DEHA2B14916g
uniprot id: Q6BW23
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

284592:DEHA2G00616g
gene id: 284592:DEHA2G00616g
uniprot id: Q6BJR1
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G07568g
gene id: 284592:DEHA2G07568g
uniprot id: Q6BIU5
names: Similarity
messages: Belongs to the PIAS family.

284592:DEHA2A13904g
gene id: 284592:DEHA2A13904g
uniprot id: Q6BXY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

284592:DEHA2D02464g
gene id: 284592:DEHA2D02464g
uniprot id: Q6BT95
names: Similarity
messages: Belongs to the WrbA family.

284592:DEHA2G22066g
gene id: 284592:DEHA2G22066g
uniprot id: Q6BH18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homodimer.
messages: Mitochondrion
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

284592:DEHA2D02838g
gene id: 284592:DEHA2D02838g
uniprot id: Q6BT80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: The COPII coat is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex, and the protein SAR1. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.

284592:DEHA2E23958g
gene id: 284592:DEHA2E23958g
uniprot id: Q6BN78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

284592:DEHA2G18282g
gene id: 284592:DEHA2G18282g
uniprot id: Q6BHI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

284592:DEHA2D08096g
gene id: 284592:DEHA2D08096g
uniprot id: Q6BSK8
names: Cofactor
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cu(2+) or Zn(2+).
messages: Mitochondrion inner membrane
messages: Monomer.
messages: Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Forms a redox cycle with ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS (By similarity).
messages: The CHCH domain contains a conserved twin Cys-X(9)-Cys motif which is required for import and stability of MIA40 in mitochondria.

284592:DEHA2F01980g
gene id: 284592:DEHA2F01980g
uniprot id: Q6BMX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

284592:DEHA2F22572g
gene id: 284592:DEHA2F22572g
uniprot id: Q6BKE7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284592:DEHA2G06886g
gene id: 284592:DEHA2G06886g
uniprot id: Q6BIX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

284592:DEHA2A06930g
gene id: 284592:DEHA2A06930g
uniprot id: Q6BYU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WRB/GET1 family.
messages: Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.

284592:DEHA2F11638g
gene id: 284592:DEHA2F11638g
uniprot id: Q6BLQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

284592:DEHA2C01100g
gene id: 284592:DEHA2C01100g
uniprot id: Q6BVP2
names: Similarity
messages: Belongs to the cytochrome P450 family.

284592:DEHA2B14300g
gene id: 284592:DEHA2B14300g
uniprot id: Q6BW53
names: Similarity
messages: Belongs to the UPP synthase family.

284592:DEHA2E19085g
gene id: 284592:DEHA2E19085g
uniprot id: Q6BNT8
names: Similarity
messages: Belongs to the pirin family.

284592:DEHA2F17094g
gene id: 284592:DEHA2F17094g
uniprot id: B5RUI4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

284592:DEHA2G01078g
gene id: 284592:DEHA2G01078g
uniprot id: Q6BJP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG10 family.
messages: E2-like enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy and nucleophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for proper localization of ATG8 to the preautophagosomal structure (PAS). Likely serves as an ATG5-recognition molecule (By similarity).
messages: Forms homooligomers.
messages: Preautophagosomal structure membrane

284592:DEHA2B05016g
gene id: 284592:DEHA2B05016g
uniprot id: Q6BX89
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

284592:DEHA2E12232g
gene id: 284592:DEHA2E12232g
uniprot id: Q6BPN2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

284592:DEHA2G10780g
gene id: 284592:DEHA2G10780g
uniprot id: Q6BIG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.
messages: Endoplasmic reticulum membrane

284592:DEHA2B04158g
gene id: 284592:DEHA2B04158g
uniprot id: Q6BXC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

284592:DEHA2G02992g
gene id: 284592:DEHA2G02992g
uniprot id: Q6BJE8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

284592:DEHA2C16126g
gene id: 284592:DEHA2C16126g
uniprot id: Q6BTT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
messages: Nucleus

284592:DEHA2E03476g
gene id: 284592:DEHA2E03476g
uniprot id: Q6BQP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

284592:DEHA2C08316g
gene id: 284592:DEHA2C08316g
uniprot id: Q6BUT0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

284592:DEHA2F21054g
gene id: 284592:DEHA2F21054g
uniprot id: Q6BKK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: nucleolus

284592:DEHA2F11880g
gene id: 284592:DEHA2F11880g
uniprot id: Q6BLP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284592:DEHA2G06006g
gene id: 284592:DEHA2G06006g
uniprot id: Q6BJ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRG7 family.
messages: Mitochondrion

284592:DEHA2B12474g
gene id: 284592:DEHA2B12474g
uniprot id: Q6BWC2
names: Function
messages: F-box protein probably involved in ubiquitin conjugation pathway.

284592:DEHA2E03960g
gene id: 284592:DEHA2E03960g
uniprot id: Q6BQM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

284592:DEHA2A09394g
gene id: 284592:DEHA2A09394g
uniprot id: Q6BYI1
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

284592:DEHA2A02750g
gene id: 284592:DEHA2A02750g
uniprot id: Q6BZB0
names: Similarity
messages: Belongs to the MSOX/MTOX family.

284592:DEHA2F26488g
gene id: 284592:DEHA2F26488g
uniprot id: Q6BJY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

284592:DEHA2F22352g
gene id: 284592:DEHA2F22352g
uniprot id: B5RUL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S10 family.
messages: Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).
messages: trans-Golgi network membrane

284592:DEHA2G20130g
gene id: 284592:DEHA2G20130g
uniprot id: Q6BHA3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284592:DEHA2B12892g
gene id: 284592:DEHA2B12892g
uniprot id: Q6BWB4
names: Function
names: Similarity
messages: Belongs to the dihydroxyacetone kinase (DAK) family.
messages: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.

284592:DEHA2E14784g
gene id: 284592:DEHA2E14784g
uniprot id: Q6BPC3
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

284592:DEHA2F22286g
gene id: 284592:DEHA2F22286g
uniprot id: Q6BKF9
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2A13156g
gene id: 284592:DEHA2A13156g
uniprot id: Q6BY18
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.

284592:DEHA2C05742g
gene id: 284592:DEHA2C05742g
uniprot id: B5RT80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: nucleolus

284592:DEHA2C04752g
gene id: 284592:DEHA2C04752g
uniprot id: Q6BV76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with DNA double-strand breaks.
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: Nucleus
messages: Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability (By similarity).
messages: telomere

284592:DEHA2B11924g
gene id: 284592:DEHA2B11924g
uniprot id: Q6BWE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP18 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking.

284592:DEHA2E20042g
gene id: 284592:DEHA2E20042g
uniprot id: Q6BNP3
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.

284592:DEHA2B13882g
gene id: 284592:DEHA2B13882g
uniprot id: Q6BW69
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D09790g
gene id: 284592:DEHA2D09790g
uniprot id: Q6BSC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG2 family.
messages: Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.
messages: Endoplasmic reticulum membrane

284592:DEHA2D11506g
gene id: 284592:DEHA2D11506g
uniprot id: Q6BS53
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

284592:DEHA2G15752g
gene id: 284592:DEHA2G15752g
uniprot id: Q6BHU4
names: Function
names: Similarity
messages: Belongs to the BLOC1S4 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex that is involved in endosomal cargo sorting.

284592:DEHA2G24420g
gene id: 284592:DEHA2G24420g
uniprot id: Q6BGR8
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

284592:DEHA2E14828g
gene id: 284592:DEHA2E14828g
uniprot id: Q6BPC1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DPH4 family.
messages: Cytoplasm
messages: Nucleus
messages: Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2 (By similarity).
messages: The DPH-type metal-binding (MB) domain can bind either zinc or iron ions.

284592:DEHA2E05390g
gene id: 284592:DEHA2E05390g
uniprot id: Q6BQG7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284592:DEHA2B11286g
gene id: 284592:DEHA2B11286g
uniprot id: Q6BWH7
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

284592:DEHA2G04048g
gene id: 284592:DEHA2G04048g
uniprot id: Q6BJ99
names: Similarity
messages: Belongs to the YOS1 family.

284592:DEHA2D01848g
gene id: 284592:DEHA2D01848g
uniprot id: Q6BTC1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

284592:DEHA2D16170g
gene id: 284592:DEHA2D16170g
uniprot id: Q6BRI2
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F10890g
gene id: 284592:DEHA2F10890g
uniprot id: Q6BLT4
names: Similarity
messages: Belongs to the EFR3 family.

284592:DEHA2F18920g
gene id: 284592:DEHA2F18920g
uniprot id: B5RUJ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

284592:DEHA2F08294g
gene id: 284592:DEHA2F08294g
uniprot id: Q6BM50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: nucleolus

284592:DEHA2D06996g
gene id: 284592:DEHA2D06996g
uniprot id: Q6BSQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

284592:DEHA2C11374g
gene id: 284592:DEHA2C11374g
uniprot id: Q6BUF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2D06952g
gene id: 284592:DEHA2D06952g
uniprot id: Q6BSQ6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

284592:DEHA2A04554g
gene id: 284592:DEHA2A04554g
uniprot id: Q6BZ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

284592:DEHA2F16456g
gene id: 284592:DEHA2F16456g
uniprot id: Q6BL47
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

284592:DEHA2E12694g
gene id: 284592:DEHA2E12694g
uniprot id: Q6BPL2
names: Similarity
messages: Belongs to the nudE family.

284592:DEHA2G19954g
gene id: 284592:DEHA2G19954g
uniprot id: Q6BHB0
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2B14322g
gene id: 284592:DEHA2B14322g
uniprot id: Q6BW52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

284592:DEHA2G20768g
gene id: 284592:DEHA2G20768g
uniprot id: Q6BH76
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Heterooctamer of 4 alpha and 4 beta chains.

284592:DEHA2G07172g
gene id: 284592:DEHA2G07172g
uniprot id: Q6BIW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

284592:DEHA2F17380g
gene id: 284592:DEHA2F17380g
uniprot id: Q6BL04
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F01386g
gene id: 284592:DEHA2F01386g
uniprot id: Q6BMZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-22 family.
messages: Involved in peroxisome biogenesis.
messages: Peroxisome membrane

284592:DEHA2E08954g
gene id: 284592:DEHA2E08954g
uniprot id: Q6BQ23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the crooked-neck family.
messages: Involved in pre-mRNA splicing and cell cycle progression.
messages: Nucleus

284592:DEHA2D09064g
gene id: 284592:DEHA2D09064g
uniprot id: Q6BSG2
names: Similarity
messages: Belongs to the TTC4 family.

284592:DEHA2A05566g
gene id: 284592:DEHA2A05566g
uniprot id: B5RSQ8
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

284592:DEHA2F00638g
gene id: 284592:DEHA2F00638g
uniprot id: Q6BN33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2C06380g
gene id: 284592:DEHA2C06380g
uniprot id: Q6BV05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2F11352g
gene id: 284592:DEHA2F11352g
uniprot id: Q6BLR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2F08888g
gene id: 284592:DEHA2F08888g
uniprot id: Q6BM23
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethan group.

284592:DEHA2A10076g
gene id: 284592:DEHA2A10076g
uniprot id: Q6BYF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FYV10 family.
messages: Cytoplasm
messages: Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.
messages: Nucleus

284592:DEHA2G16500g
gene id: 284592:DEHA2G16500g
uniprot id: Q6BHR3
names: Similarity
messages: Belongs to the UPF0047 family.

284592:DEHA2E05214g
gene id: 284592:DEHA2E05214g
uniprot id: Q6BQH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane. Modulates the mitochondrial matrix zinc pool (By similarity).
messages: Belongs to the complex I LYR family. MZM1 subfamily.
messages: Interacts with RIP1.
messages: Mitochondrion matrix

284592:DEHA2F02992g
gene id: 284592:DEHA2F02992g
uniprot id: Q6BMS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

284592:DEHA2G03322g
gene id: 284592:DEHA2G03322g
uniprot id: Q6BJD1
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284592:DEHA2D18612g
gene id: 284592:DEHA2D18612g
uniprot id: B5RTM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

284592:DEHA2A01892g
gene id: 284592:DEHA2A01892g
uniprot id: Q6BZE9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Endosome membrane
messages: Preautophagosomal structure membrane
messages: Sorting nexin, involved in the separation or division of vacuoles throughout the entire life cycle of the cells. Involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network, for cytoplasm to vacuole transport (Cvt), autophagy, mitophagy, and pexophagy.
messages: The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization to the perivacuolar punctate structures.
messages: cytosol

284592:DEHA2A02420g
gene id: 284592:DEHA2A02420g
uniprot id: Q6BZC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NMT1/THI5 family.
messages: Homodimer.
messages: Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway. Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP). The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.

284592:DEHA2F15884g
gene id: 284592:DEHA2F15884g
uniprot id: Q6BL71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

284592:DEHA2F17534g
gene id: 284592:DEHA2F17534g
uniprot id: Q6BKZ7
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

284592:DEHA2B05236g
gene id: 284592:DEHA2B05236g
uniprot id: Q6BX79
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2E23056g
gene id: 284592:DEHA2E23056g
uniprot id: Q6BNB9
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G07260g
gene id: 284592:DEHA2G07260g
uniprot id: B5RV48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2D02156g
gene id: 284592:DEHA2D02156g
uniprot id: Q6BTA9
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

284592:DEHA2F26180g
gene id: 284592:DEHA2F26180g
uniprot id: Q6BJZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

284592:DEHA2F26026g
gene id: 284592:DEHA2F26026g
uniprot id: Q6BK00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-3 family.
messages: Involved in peroxisome biosynthesis.
messages: Peroxisome membrane

284592:DEHA2E14894g
gene id: 284592:DEHA2E14894g
uniprot id: Q6BPB8
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

284592:DEHA2E03630g
gene id: 284592:DEHA2E03630g
uniprot id: Q6BQN8
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

284592:DEHA2C11946g
gene id: 284592:DEHA2C11946g
uniprot id: Q6BUC4
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

284592:DEHA2F25036g
gene id: 284592:DEHA2F25036g
uniprot id: Q6BK43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

284592:DEHA2C13970g
gene id: 284592:DEHA2C13970g
uniprot id: Q6BU33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

284592:DEHA2C09284g
gene id: 284592:DEHA2C09284g
uniprot id: Q6BUN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DUO1 family.
messages: Nucleus
messages: kinetochore

284592:DEHA2E02838g
gene id: 284592:DEHA2E02838g
uniprot id: Q6BQR8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As accessory component of the DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication.
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Heterotetramer. Consists of four subunits: POL2, DPB2, DPB3 and DPB4 (By similarity).
messages: In eukaryotes there are five DNA polymerases: alpha, beta, gamma, delta, and epsilon which are responsible for different reactions of DNA synthesis.
messages: Nucleus

284592:DEHA2G09988g
gene id: 284592:DEHA2G09988g
uniprot id: Q6BIJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 14, 12 and 17 subunits, respectively.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process (By similarity).
messages: Nucleus

284592:DEHA2C02354g
gene id: 284592:DEHA2C02354g
uniprot id: Q6BVI7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

284592:DEHA2C05148g
gene id: 284592:DEHA2C05148g
uniprot id: Q6BV59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

284592:DEHA2C10758g
gene id: 284592:DEHA2C10758g
uniprot id: Q6BUG8
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

284592:DEHA2B13002g
gene id: 284592:DEHA2B13002g
uniprot id: Q6BWA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

284592:DEHA2F26994g
gene id: 284592:DEHA2F26994g
uniprot id: Q6BJV9
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

284592:DEHA2F20724g
gene id: 284592:DEHA2F20724g
uniprot id: Q6BKM2
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2C15642g
gene id: 284592:DEHA2C15642g
uniprot id: Q6BTV6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

284592:DEHA2G00726g
gene id: 284592:DEHA2G00726g
uniprot id: Q6BJQ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

284592:DEHA2E09262g
gene id: 284592:DEHA2E09262g
uniprot id: Q6BQ09
names: Similarity
messages: Belongs to the pantothenate synthetase family.

284592:DEHA2C00297g
gene id: 284592:DEHA2C00297g
uniprot id: W0TYR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2A06798g
gene id: 284592:DEHA2A06798g
uniprot id: Q6BYU9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

284592:DEHA2C02706g
gene id: 284592:DEHA2C02706g
uniprot id: Q6BVH2
names: Similarity
messages: Belongs to the BMT family.

284592:DEHA2A03674g
gene id: 284592:DEHA2A03674g
uniprot id: B5RSQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-Z subfamily.
messages: Cytoplasm

284592:DEHA2C01826g
gene id: 284592:DEHA2C01826g
uniprot id: Q6BVK9
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

284592:DEHA2E19954g
gene id: 284592:DEHA2E19954g
uniprot id: Q6BNP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

284592:DEHA2E22946g
gene id: 284592:DEHA2E22946g
uniprot id: Q6BNC3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

284592:DEHA2F04444g
gene id: 284592:DEHA2F04444g
uniprot id: Q6BML2
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E02332g
gene id: 284592:DEHA2E02332g
uniprot id: Q6BQT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: The COPII coat is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex, and the protein SAR1.

284592:DEHA2G08074g
gene id: 284592:DEHA2G08074g
uniprot id: Q6BIS2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YPT35 family.
messages: Endosome membrane
messages: Recruits the lipid transfer protein VPS13 to endosomal and vacuolar membranes.
messages: The PX domain binds phosphatidylinositol 3-phosphate (PtdIns(3)P) which is necessary for peripheral membrane localization.
messages: Vacuole membrane

284592:DEHA2G06754g
gene id: 284592:DEHA2G06754g
uniprot id: Q6BIY0
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2B03740g
gene id: 284592:DEHA2B03740g
uniprot id: Q6BXE4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

284592:DEHA2E06072g
gene id: 284592:DEHA2E06072g
uniprot id: Q6BQD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

284592:DEHA2F08316g
gene id: 284592:DEHA2F08316g
uniprot id: Q6BM49
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

284592:DEHA2D02112g
gene id: 284592:DEHA2D02112g
uniprot id: Q6BTB1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+) is required for catalysis and for stabilizing the dimer.

284592:DEHA2D08426g
gene id: 284592:DEHA2D08426g
uniprot id: Q6BSJ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

284592:DEHA2F10230g
gene id: 284592:DEHA2F10230g
uniprot id: Q6BLW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: coated pit

284592:DEHA2C12826g
gene id: 284592:DEHA2C12826g
uniprot id: Q6BU86
names: Similarity
messages: Belongs to the phosducin family.

284592:DEHA2D04950g
gene id: 284592:DEHA2D04950g
uniprot id: Q6BSY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LCL3 family.
messages: Membrane
messages: Mitochondrion

284592:DEHA2F01518g
gene id: 284592:DEHA2F01518g
uniprot id: Q6BMZ1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.

284592:DEHA2E15620g
gene id: 284592:DEHA2E15620g
uniprot id: B5RU18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the midasin family.
messages: Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits.
messages: nucleolus
messages: nucleoplasm

284592:DEHA2C13244g
gene id: 284592:DEHA2C13244g
uniprot id: Q6BU65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion inner membrane
messages: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.

284592:DEHA2B00968g
gene id: 284592:DEHA2B00968g
uniprot id: Q6BXQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

284592:DEHA2G17798g
gene id: 284592:DEHA2G17798g
uniprot id: Q6BHK8
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

284592:DEHA2E21164g
gene id: 284592:DEHA2E21164g
uniprot id: Q6BNJ6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds to both phosphatidylinositol (PI) and phosphatidylinositol 3,5-bisphosphate (PIP2).
messages: Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by ATG15 is critical to life span extension.
messages: Prevacuolar compartment membrane
messages: multivesicular body membrane

284592:DEHA2C08800g
gene id: 284592:DEHA2C08800g
uniprot id: B5RT91
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

284592:DEHA2E17622g
gene id: 284592:DEHA2E17622g
uniprot id: Q6BP04
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F26422g
gene id: 284592:DEHA2F26422g
uniprot id: Q6BJY4
names: Similarity
messages: Belongs to the KNR4/SMI1 family.

284592:DEHA2B02090g
gene id: 284592:DEHA2B02090g
uniprot id: Q6BXL1
names: Similarity
messages: Belongs to the RRP15 family.

284592:DEHA2F04092g
gene id: 284592:DEHA2F04092g
uniprot id: Q6BMM7
names: Similarity
messages: Belongs to the lysophospholipase family.

284592:DEHA2A09306g
gene id: 284592:DEHA2A09306g
uniprot id: Q6BYI5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS7 family.

284592:DEHA2G01386g
gene id: 284592:DEHA2G01386g
uniprot id: Q6BJM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2G06930g
gene id: 284592:DEHA2G06930g
uniprot id: Q6BIX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

284592:DEHA2C13552g
gene id: 284592:DEHA2C13552g
uniprot id: Q6BU52
names: Similarity
messages: Belongs to the isochorismatase family.

284592:DEHA2C01958g
gene id: 284592:DEHA2C01958g
uniprot id: Q6BVK3
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

284592:DEHA2G07106g
gene id: 284592:DEHA2G07106g
uniprot id: Q6BIW4
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

284592:DEHA2E01892g
gene id: 284592:DEHA2E01892g
uniprot id: Q6BQV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Clp1 family. NOL9/GRC3 subfamily.
messages: Polynucleotide 5'-kinase involved in rRNA processing.
messages: nucleolus

284592:DEHA2F17622g
gene id: 284592:DEHA2F17622g
uniprot id: Q6BKZ5
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

284592:DEHA2G12958g
gene id: 284592:DEHA2G12958g
uniprot id: Q6BI70
names: Similarity
messages: Belongs to the APC13 family.

284592:DEHA2F20174g
gene id: 284592:DEHA2F20174g
uniprot id: Q6BKP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

284592:DEHA2G13376g
gene id: 284592:DEHA2G13376g
uniprot id: B5RUS0
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

284592:DEHA2G04224g
gene id: 284592:DEHA2G04224g
uniprot id: Q6BJ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

284592:DEHA2G10560g
gene id: 284592:DEHA2G10560g
uniprot id: Q6BIG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

284592:DEHA2D13860g
gene id: 284592:DEHA2D13860g
uniprot id: Q6BRU0
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

284592:DEHA2F06006g
gene id: 284592:DEHA2F06006g
uniprot id: Q6BMF0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

284592:DEHA2F06138g
gene id: 284592:DEHA2F06138g
uniprot id: Q6BME5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 also plays a role in pre-mRNA splicing and spliceosome assembly. May be involved in rDNA and telomeric silencing, and maintenance of genome integrity (By similarity).
messages: Belongs to the DEAD box helicase family. DECD subfamily.
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284592:DEHA2C16698g
gene id: 284592:DEHA2C16698g
uniprot id: Q6BTQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Required both for recombination and for the repair of DNA damage caused by X-rays.

284592:DEHA2C11660g
gene id: 284592:DEHA2C11660g
uniprot id: Q6BUD7
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

284592:DEHA2D17402g
gene id: 284592:DEHA2D17402g
uniprot id: Q6BRC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LOC1 family.
messages: Component of the 66S pre-ribosomal particle.
messages: Required for efficient assembly and nuclear export of the 60S ribosomal subunit.
messages: nucleolus

284592:DEHA2C07546g
gene id: 284592:DEHA2C07546g
uniprot id: Q6BUW0
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

284592:DEHA2B07084g
gene id: 284592:DEHA2B07084g
uniprot id: Q6BX03
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D10120g
gene id: 284592:DEHA2D10120g
uniprot id: Q6BSB5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

284592:DEHA2G09702g
gene id: 284592:DEHA2G09702g
uniprot id: Q6BIK3
names: Similarity
messages: Belongs to the BRX1 family.

284592:DEHA2A08976g
gene id: 284592:DEHA2A08976g
uniprot id: Q6BYJ9
names: Similarity
messages: Belongs to the group II decarboxylase family.

284592:DEHA2F01452g
gene id: 284592:DEHA2F01452g
uniprot id: Q6BMZ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

284592:DEHA2D06182g
gene id: 284592:DEHA2D06182g
uniprot id: Q6BSU3
names: Similarity
messages: Belongs to the cytochrome P450 family.

284592:DEHA2E20790g
gene id: 284592:DEHA2E20790g
uniprot id: Q6BNL4
names: Subcellular Location Annotation
messages: Cytoplasm

284592:DEHA2G21098g
gene id: 284592:DEHA2G21098g
uniprot id: Q6BH61
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2D15488g
gene id: 284592:DEHA2D15488g
uniprot id: Q6BRL4
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2D15730g
gene id: 284592:DEHA2D15730g
uniprot id: Q6BRK2
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

284592:DEHA2D17798g
gene id: 284592:DEHA2D17798g
uniprot id: Q6BRB0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

284592:DEHA2E10362g
gene id: 284592:DEHA2E10362g
uniprot id: B5RTZ1
names: Similarity
messages: Belongs to the Cdt1 family.

284592:DEHA2D12716g
gene id: 284592:DEHA2D12716g
uniprot id: Q6BRZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

284592:DEHA2G14718g
gene id: 284592:DEHA2G14718g
uniprot id: B5RUT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

284592:DEHA2E02596g
gene id: 284592:DEHA2E02596g
uniprot id: B5RTT3
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D06820g
gene id: 284592:DEHA2D06820g
uniprot id: Q6BSR4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

284592:DEHA2D16236g
gene id: 284592:DEHA2D16236g
uniprot id: Q6BRH9
names: Function
names: Similarity
messages: Belongs to the IRS4 family.
messages: Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity).

284592:DEHA2C12298g
gene id: 284592:DEHA2C12298g
uniprot id: Q6BUB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

284592:DEHA2E22726g
gene id: 284592:DEHA2E22726g
uniprot id: Q6BND2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fungal TPase family.
messages: First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.
messages: Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.
messages: Nucleus

284592:DEHA2F04466g
gene id: 284592:DEHA2F04466g
uniprot id: Q6BML1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
messages: Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284592:DEHA2B02772g
gene id: 284592:DEHA2B02772g
uniprot id: B5RT30
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G17446g
gene id: 284592:DEHA2G17446g
uniprot id: Q6BHM3
names: Similarity
messages: Belongs to the OSBP family.

284592:DEHA2F16720g
gene id: 284592:DEHA2F16720g
uniprot id: Q6BL34
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284592:DEHA2B11880g
gene id: 284592:DEHA2B11880g
uniprot id: Q6BWE9
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C16038g
gene id: 284592:DEHA2C16038g
uniprot id: Q6BTT5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

284592:DEHA2E15092g
gene id: 284592:DEHA2E15092g
uniprot id: Q6BPA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NUF2 family.
messages: Component of the NDC80 complex, which consists of NDC80, NUF2, SPC24 and SPC25.
messages: Nucleus
messages: kinetochore

284592:DEHA2F14938g
gene id: 284592:DEHA2F14938g
uniprot id: Q6BLB2
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G13508g
gene id: 284592:DEHA2G13508g
uniprot id: Q6BI46
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

284592:DEHA2F26950g
gene id: 284592:DEHA2F26950g
uniprot id: W0TYU4
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

284592:DEHA2E19756g
gene id: 284592:DEHA2E19756g
uniprot id: Q6BNQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with cytochrome c oxidase (complex IV, CIV).
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Mitochondrion inner membrane

284592:DEHA2B03256g
gene id: 284592:DEHA2B03256g
uniprot id: Q6BXG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

284592:DEHA2C03564g
gene id: 284592:DEHA2C03564g
uniprot id: Q6BVD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

284592:DEHA2C12804g
gene id: 284592:DEHA2C12804g
uniprot id: Q6BU87
names: Similarity
messages: Belongs to the peptidase C19 family.

284592:DEHA2B05258g
gene id: 284592:DEHA2B05258g
uniprot id: Q6BX78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with TRM82.
messages: Nucleus

284592:DEHA2D07370g
gene id: 284592:DEHA2D07370g
uniprot id: Q6BSN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
messages: Cytoplasm
messages: Nucleus
messages: Part of the nascent polypeptide-associated complex (NAC), consisting of EGD2 and EGD1. NAC associates with ribosomes via EGD1 (By similarity).

284592:DEHA2B13618g
gene id: 284592:DEHA2B13618g
uniprot id: Q6BW81
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

284592:DEHA2C07260g
gene id: 284592:DEHA2C07260g
uniprot id: Q6BUX1
names: Similarity
messages: Belongs to the TPA1 family.

284592:DEHA2D09416g
gene id: 284592:DEHA2D09416g
uniprot id: Q6BSE6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

284592:DEHA2A05632g
gene id: 284592:DEHA2A05632g
uniprot id: Q6BZ02
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

284592:DEHA2G12980g
gene id: 284592:DEHA2G12980g
uniprot id: Q6BI69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Forms the polymerase active center together with the second largest subunit. A single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III. A bridging helix emanates from RPC1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol III by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition (By similarity).
messages: Nucleus

284592:DEHA2G12496g
gene id: 284592:DEHA2G12496g
uniprot id: Q6BI94
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2G23606g
gene id: 284592:DEHA2G23606g
uniprot id: Q6BGV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
messages: nucleolus

284592:DEHA2C11000g
gene id: 284592:DEHA2C11000g
uniprot id: Q6BUF8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

284592:DEHA2D03916g
gene id: 284592:DEHA2D03916g
uniprot id: Q6BT33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chitin synthase family.
messages: Cell membrane
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

284592:DEHA2G13222g
gene id: 284592:DEHA2G13222g
uniprot id: Q6BI59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Heterodimers with GPN1 or GPN2. Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

284592:DEHA2E02266g
gene id: 284592:DEHA2E02266g
uniprot id: Q6BQT9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

284592:DEHA2G17732g
gene id: 284592:DEHA2G17732g
uniprot id: O42724
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homodimer.

284592:DEHA2G05830g
gene id: 284592:DEHA2G05830g
uniprot id: Q6BJ21
names: Similarity
messages: Belongs to the AHA1 family.

284592:DEHA2C00330g
gene id: 284592:DEHA2C00330g
uniprot id: Q6BVS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNN1/MNT family.
messages: Golgi apparatus membrane
messages: Membrane

284592:DEHA2F20988g
gene id: 284592:DEHA2F20988g
uniprot id: Q6BKK9
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

284592:DEHA2E15070g
gene id: 284592:DEHA2E15070g
uniprot id: Q6BPB0
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G21142g
gene id: 284592:DEHA2G21142g
uniprot id: B5RUW9
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.

284592:DEHA2G13838g
gene id: 284592:DEHA2G13838g
uniprot id: B5RUS5
names: Similarity
messages: Belongs to the protein kinase superfamily.

284592:DEHA2E13420g
gene id: 284592:DEHA2E13420g
uniprot id: Q6BPI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

284592:DEHA2B10186g
gene id: 284592:DEHA2B10186g
uniprot id: Q6BWM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

284592:DEHA2B07040g
gene id: 284592:DEHA2B07040g
uniprot id: B5RSX6
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

284592:DEHA2E13772g
gene id: 284592:DEHA2E13772g
uniprot id: B5RU12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

284592:DEHA2C09702g
gene id: 284592:DEHA2C09702g
uniprot id: Q6BUL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28A subfamily.
messages: May be involved in vacuolar sorting and osmoregulation.
messages: Membrane
messages: Vacuole membrane

284592:DEHA2F10516g
gene id: 284592:DEHA2F10516g
uniprot id: Q6BLV0
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F24706g
gene id: 284592:DEHA2F24706g
uniprot id: B5RUN5
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E20746g
gene id: 284592:DEHA2E20746g
uniprot id: Q6BNL6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in cell cycle progression and meiosis (By similarity).
messages: Interacts with H3K4me3 and to a lesser extent with H3K4me2. Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

284592:DEHA2G16676g
gene id: 284592:DEHA2G16676g
uniprot id: Q6BHQ5
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

284592:DEHA2F21032g
gene id: 284592:DEHA2F21032g
uniprot id: Q6BKK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer; composed of two copies of TRM6 and two copies of TRM61.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

284592:DEHA2C04444g
gene id: 284592:DEHA2C04444g
uniprot id: Q6BV91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SNW family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284592:DEHA2C12562g
gene id: 284592:DEHA2C12562g
uniprot id: Q6BU98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of a pre-mRNA cleavage factor complex. Interacts directly with PCF11.
messages: May lack the polyribonucleotide 5'-hydroxyl-kinase and polynucleotide 5'-hydroxyl-kinase activities that are characteristic of the human ortholog.
messages: Nucleus
messages: Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.

284592:DEHA2E20020g
gene id: 284592:DEHA2E20020g
uniprot id: Q6BNP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

284592:DEHA2C04246g
gene id: 284592:DEHA2C04246g
uniprot id: Q6BVA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: Nucleus
messages: Required for high-fidelity chromosome segregation during the later part of each cell cycle. Acts in opposition to the phosphatase PP1. Has a role in attaching the kinetochores to the microtubules and ensuring that sister kinetochores connect to opposite poles. The promotion of bi-orientation is achieved by selectively detaching kinetochore-microtubule attachments that are not under tension. Phosphorylates histone H3 to form H3S10ph during mitosis and meiosis (By similarity).
messages: kinetochore
messages: spindle

284592:DEHA2B15818g
gene id: 284592:DEHA2B15818g
uniprot id: B5RSW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

284592:DEHA2F16544g
gene id: 284592:DEHA2F16544g
uniprot id: Q6BL43
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

284592:DEHA2C07810g
gene id: 284592:DEHA2C07810g
uniprot id: Q6BUV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

284592:DEHA2C08888g
gene id: 284592:DEHA2C08888g
uniprot id: Q6BUQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

284592:DEHA2C17864g
gene id: 284592:DEHA2C17864g
uniprot id: Q6BTJ8
names: Similarity
messages: Belongs to the peptidase A1 family.

284592:DEHA2F07612g
gene id: 284592:DEHA2F07612g
uniprot id: B5RUB4
names: Similarity
messages: Belongs to the TMCO4 family.

284592:DEHA2A06292g
gene id: 284592:DEHA2A06292g
uniprot id: Q6BYX2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

284592:DEHA2A10384g
gene id: 284592:DEHA2A10384g
uniprot id: Q6BYD4
names: Similarity
messages: In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.

284592:DEHA2A12320g
gene id: 284592:DEHA2A12320g
uniprot id: Q6BY53
names: Similarity
messages: Belongs to the LacAB/RpiB family.

284592:DEHA2F09328g
gene id: 284592:DEHA2F09328g
uniprot id: Q6BM05
names: Similarity
messages: Belongs to the LST4 family.

284592:DEHA2E19910g
gene id: 284592:DEHA2E19910g
uniprot id: Q6BNP9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

284592:DEHA2B07458g
gene id: 284592:DEHA2B07458g
uniprot id: Q6BWY6
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

284592:DEHA2C05324g
gene id: 284592:DEHA2C05324g
uniprot id: Q6BV50
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

284592:DEHA2D17204g
gene id: 284592:DEHA2D17204g
uniprot id: Q6BRD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

284592:DEHA2G11880g
gene id: 284592:DEHA2G11880g
uniprot id: Q6BIC3
names: Subcellular Location Annotation
messages: Peroxisome membrane

284592:DEHA2G07480g
gene id: 284592:DEHA2G07480g
uniprot id: Q6BIU8
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

284592:DEHA2D03762g
gene id: 284592:DEHA2D03762g
uniprot id: B5RTQ9
names: Similarity
messages: Belongs to the protein kinase superfamily.

284592:DEHA2E09548g
gene id: 284592:DEHA2E09548g
uniprot id: Q6BPZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex, which consists of NDC80, NUF2, SPC24 and SPC25.
messages: Nucleus
messages: kinetochore

284592:DEHA2A12122g
gene id: 284592:DEHA2A12122g
uniprot id: Q6BY62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Component of the GSE complex.
messages: GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.

284592:DEHA2B10824g
gene id: 284592:DEHA2B10824g
uniprot id: Q6BWJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR55 family.
messages: nucleolus

284592:DEHA2F03058g
gene id: 284592:DEHA2F03058g
uniprot id: Q6BMS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Nucleus
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.

284592:DEHA2F21142g
gene id: 284592:DEHA2F21142g
uniprot id: Q6BKK3
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2A13662g
gene id: 284592:DEHA2A13662g
uniprot id: Q6BXZ6
names: Similarity
messages: Belongs to the protein kinase superfamily.

284592:DEHA2G01232g
gene id: 284592:DEHA2G01232g
uniprot id: Q6BJN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

284592:DEHA2B08426g
gene id: 284592:DEHA2B08426g
uniprot id: Q6BWU6
names: Similarity
messages: Belongs to the uridine kinase family.

284592:DEHA2D18480g
gene id: 284592:DEHA2D18480g
uniprot id: Q6BR82
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

284592:DEHA2B16500g
gene id: 284592:DEHA2B16500g
uniprot id: Q6BVV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2B03212g
gene id: 284592:DEHA2B03212g
uniprot id: Q6BXG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDA11 family.
messages: Cytoplasm

284592:DEHA2E10186g
gene id: 284592:DEHA2E10186g
uniprot id: Q6BPX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Nucleus

284592:DEHA2B13970g
gene id: 284592:DEHA2B13970g
uniprot id: B5RT03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKN1/KRE6 family.
messages: Membrane

284592:DEHA2F25146g
gene id: 284592:DEHA2F25146g
uniprot id: Q6BK38
names: Similarity
messages: Belongs to the peptidase M67A family.

284592:DEHA2D10428g
gene id: 284592:DEHA2D10428g
uniprot id: Q6BSA1
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2F03432g
gene id: 284592:DEHA2F03432g
uniprot id: Q6BMQ6
names: Similarity
messages: Belongs to the GCN1 family.

284592:DEHA2E15796g
gene id: 284592:DEHA2E15796g
uniprot id: Q6BP80
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Early endosome membrane
messages: Golgi apparatus membrane
messages: Palmitoyltransferase specific for casein kinase 1.
messages: The DHHC domain is required for palmitoyltransferase activity.

284592:DEHA2G19910g
gene id: 284592:DEHA2G19910g
uniprot id: Q6BHB2
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

284592:DEHA2G17578g
gene id: 284592:DEHA2G17578g
uniprot id: Q6BHL9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion outer membrane
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis.

284592:DEHA2G24838g
gene id: 284592:DEHA2G24838g
uniprot id: Q6BGP9
names: Similarity
messages: Belongs to the BMT family.

284592:DEHA2C01804g
gene id: 284592:DEHA2C01804g
uniprot id: Q6BVL0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.

284592:DEHA2G23166g
gene id: 284592:DEHA2G23166g
uniprot id: Q6BGX2
names: Similarity
messages: Belongs to the NOC2 family.

284592:DEHA2D09042g
gene id: 284592:DEHA2D09042g
uniprot id: Q6BSG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Nucleus
messages: spindle

284592:DEHA2B07172g
gene id: 284592:DEHA2B07172g
uniprot id: Q6BWZ9
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D13332g
gene id: 284592:DEHA2D13332g
uniprot id: Q6BRW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

284592:DEHA2D08184g
gene id: 284592:DEHA2D08184g
uniprot id: Q6BSK4
names: Similarity
messages: Belongs to the CDC73 family.

284592:DEHA2F07128g
gene id: 284592:DEHA2F07128g
uniprot id: Q6BMA2
names: Similarity
messages: Belongs to the peptidase M20A family.

284592:DEHA2E10692g
gene id: 284592:DEHA2E10692g
uniprot id: Q6BPU8
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

284592:DEHA2G06534g
gene id: 284592:DEHA2G06534g
uniprot id: Q6BIZ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

284592:DEHA2E12628g
gene id: 284592:DEHA2E12628g
uniprot id: Q6BPL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

284592:DEHA2D07216g
gene id: 284592:DEHA2D07216g
uniprot id: Q6BSP5
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

284592:DEHA2B13244g
gene id: 284592:DEHA2B13244g
uniprot id: Q6BW98
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284592:DEHA2C03278g
gene id: 284592:DEHA2C03278g
uniprot id: Q6BVE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

284592:DEHA2F02398g
gene id: 284592:DEHA2F02398g
uniprot id: Q6BMV2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Autopalmitoylated.
messages: Belongs to the DHHC palmitoyltransferase family. PFA3 subfamily.
messages: Palmitoyltransferase specific for VAC8. Palmitoylates VAC8 at one or more of its N-terminal cysteine residues, which is required for its proper membrane localization (By similarity).
messages: The DHHC domain is required for palmitoyltransferase activity.
messages: Vacuole membrane

284592:DEHA2F14564g
gene id: 284592:DEHA2F14564g
uniprot id: Q6BLC6
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E17138g
gene id: 284592:DEHA2E17138g
uniprot id: Q6BP23
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. SWF1 subfamily.
messages: Endoplasmic reticulum membrane
messages: Palmitoyltransferase that targets several endosomal SNAREs. Palmitoylates the SNAREs at cysteine residues close to the cytoplasmic end of their transmembrane domain. May have a role in the cellular quality control of transmembrane domain-containing proteins (By similarity).
messages: The DHHC domain is required for palmitoyltransferase activity.

284592:DEHA2D11550g
gene id: 284592:DEHA2D11550g
uniprot id: Q6BS51
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

284592:DEHA2E04026g
gene id: 284592:DEHA2E04026g
uniprot id: Q6BQM2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

284592:DEHA2B15444g
gene id: 284592:DEHA2B15444g
uniprot id: Q6BVZ8
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

284592:DEHA2E10890g
gene id: 284592:DEHA2E10890g
uniprot id: Q6BPT9
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

284592:DEHA2C14784g
gene id: 284592:DEHA2C14784g
uniprot id: Q6BTZ3
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

284592:DEHA2G22088g
gene id: 284592:DEHA2G22088g
uniprot id: Q6BH17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2D14014g
gene id: 284592:DEHA2D14014g
uniprot id: Q6BRT3
names: Similarity
messages: Belongs to the PPP4R2 family.

284592:DEHA2G18546g
gene id: 284592:DEHA2G18546g
uniprot id: Q6BHH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

284592:DEHA2C10010g
gene id: 284592:DEHA2C10010g
uniprot id: Q6BUK0
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

284592:DEHA2B15092g
gene id: 284592:DEHA2B15092g
uniprot id: Q6BW15
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2B02882g
gene id: 284592:DEHA2B02882g
uniprot id: Q6BXH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MEF2 family.
messages: Nucleus

284592:DEHA2D17314g
gene id: 284592:DEHA2D17314g
uniprot id: B5RTJ9
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

284592:DEHA2F09944g
gene id: 284592:DEHA2F09944g
uniprot id: Q6BLX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Nucleus

284592:DEHA2G01320g
gene id: 284592:DEHA2G01320g
uniprot id: Q6BJM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXR1 family.
messages: May be involved in protection from oxidative damage.
messages: Mitochondrion

284592:DEHA2D10296g
gene id: 284592:DEHA2D10296g
uniprot id: Q6BSA7
names: Similarity
messages: Belongs to the protein kinase superfamily.

284592:DEHA2F21076g
gene id: 284592:DEHA2F21076g
uniprot id: Q6BKK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus

284592:DEHA2G02156g
gene id: 284592:DEHA2G02156g
uniprot id: Q6BJI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

284592:DEHA2F26444g
gene id: 284592:DEHA2F26444g
uniprot id: Q6BJY3
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

284592:DEHA2G20636g
gene id: 284592:DEHA2G20636g
uniprot id: Q6BH82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

284592:DEHA2C16192g
gene id: 284592:DEHA2C16192g
uniprot id: Q6BTS8
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2G07810g
gene id: 284592:DEHA2G07810g
uniprot id: Q6BIT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

284592:DEHA2E11022g
gene id: 284592:DEHA2E11022g
uniprot id: Q6BPT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

284592:DEHA2G14322g
gene id: 284592:DEHA2G14322g
uniprot id: Q6BI10
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

284592:DEHA2E09108g
gene id: 284592:DEHA2E09108g
uniprot id: Q6BQ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284592:DEHA2G24948g
gene id: 284592:DEHA2G24948g
uniprot id: Q6BGP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2G01188g
gene id: 284592:DEHA2G01188g
uniprot id: Q6BJN2
names: Function
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

284592:DEHA2C15400g
gene id: 284592:DEHA2C15400g
uniprot id: Q6BTW5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPH3 family.
messages: Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.
messages: Cytoplasm
messages: Nucleus
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising KTI11/DPH3 and a NADH-dependent reductase, predominantly CBR1. Acts as an electron donor to reduce the Fe-S cluster in DPH1-DPH2 keeping the [4Fe-4S] clusters in the active and reduced state. Restores iron to DPH1-DPH2 iron-sulfur clusters which have degraded from [4Fe-4S] to [3Fe-4S] by donating an iron atom to reform [4Fe-4S] clusters, in a manner dependent on the presence of elongation factor 2 and SAM. Associates with the elongator complex and is required for tRNA Wobble base modifications mediated by the elongator complex. The elongator complex is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine).
messages: The DPH-type metal-binding (MB) domain can also bind zinc. However, iron is the physiological binding partner as zinc binding impairs the protein electron donor function.

284592:DEHA2F20944g
gene id: 284592:DEHA2F20944g
uniprot id: Q6BKL1
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G10010g
gene id: 284592:DEHA2G10010g
uniprot id: Q6BII9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.
messages: Homodimer.

284592:DEHA2G21516g
gene id: 284592:DEHA2G21516g
uniprot id: B5RUX2
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

284592:DEHA2C01518g
gene id: 284592:DEHA2C01518g
uniprot id: Q6BVM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

284592:DEHA2E03256g
gene id: 284592:DEHA2E03256g
uniprot id: Q6BQQ2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

284592:DEHA2G16258g
gene id: 284592:DEHA2G16258g
uniprot id: Q6BHR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS35 family.
messages: Involved in mitochondrial genome encoded proteins translation.
messages: Mitochondrion

284592:DEHA2F15246g
gene id: 284592:DEHA2F15246g
uniprot id: Q6BL98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

284592:DEHA2G13794g
gene id: 284592:DEHA2G13794g
uniprot id: Q6BI32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TEC1 family.
messages: Nucleus

284592:DEHA2G08052g
gene id: 284592:DEHA2G08052g
uniprot id: Q6BIS3
names: Similarity
messages: Belongs to the complex I NDUFA12 subunit family.

284592:DEHA2E06094g
gene id: 284592:DEHA2E06094g
uniprot id: Q6BQD2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.

284592:DEHA2D05126g
gene id: 284592:DEHA2D05126g
uniprot id: Q6BSY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAD1 family.
messages: Central component of the spindle assembly checkpoint.
messages: Nucleus

284592:DEHA2F01562g
gene id: 284592:DEHA2F01562g
uniprot id: Q6BMY9
names: Similarity
messages: Belongs to the PHF5 family.

284592:DEHA2E15576g
gene id: 284592:DEHA2E15576g
uniprot id: Q6BP89
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

284592:DEHA2A02530g
gene id: 284592:DEHA2A02530g
uniprot id: Q6BZC0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284592:DEHA2A06864g
gene id: 284592:DEHA2A06864g
uniprot id: Q6BYU6
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

284592:DEHA2G08008g
gene id: 284592:DEHA2G08008g
uniprot id: Q6BIS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

284592:DEHA2F03652g
gene id: 284592:DEHA2F03652g
uniprot id: Q6BMP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNUT3 family.
messages: May play a role in mRNA splicing.
messages: Nucleus
messages: Part of a tri-snRNP complex.

284592:DEHA2G00880g
gene id: 284592:DEHA2G00880g
uniprot id: Q6BJP9
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F13266g
gene id: 284592:DEHA2F13266g
uniprot id: Q6BLI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: actin patch

284592:DEHA2G23474g
gene id: 284592:DEHA2G23474g
uniprot id: Q6BGW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Histone acetyltransferase that acetylates histone H2B to form H2BK11ac and H2BK16ac, histone H3 to form H3K14ac, with a lower preference histone H4 to form H4K8ac and H4K16ac, and contributes to H2A.Z acetylation. Acetylation of histones gives a specific tag for epigenetic transcription activation. In addition to histone acetyltransferase, can use different acyl-CoA substrates, such as (2E)-butenoyl-CoA (crotonyl-CoA) and is able to mediate histone crotonylation.
messages: Nucleus

284592:DEHA2G07986g
gene id: 284592:DEHA2G07986g
uniprot id: Q6BIS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane

284592:DEHA2F06248g
gene id: 284592:DEHA2F06248g
uniprot id: Q6BMD9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

284592:DEHA2A02046g
gene id: 284592:DEHA2A02046g
uniprot id: Q6BZE1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Endosome membrane
messages: Preautophagosomal structure membrane
messages: Required for cytoplasm to vacuole transport (Cvt), pexophagy and mitophagy. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Functions in protein retrieval from the endocytic pathway (By similarity).
messages: The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization to the perivacuolar punctate structures.

284592:DEHA2E16654g
gene id: 284592:DEHA2E16654g
uniprot id: Q6BP44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane

284592:DEHA2D01232g
gene id: 284592:DEHA2D01232g
uniprot id: Q6BTE8
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2A04862g
gene id: 284592:DEHA2A04862g
uniprot id: Q6BZ36
names: Similarity
messages: Belongs to the SDHAF4 family.

284592:DEHA2F04686g
gene id: 284592:DEHA2F04686g
uniprot id: B5RU97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284592:DEHA2A13574g
gene id: 284592:DEHA2A13574g
uniprot id: Q6BY00
names: Similarity
messages: Belongs to the activator 1 small subunits family.

284592:DEHA2B03300g
gene id: 284592:DEHA2B03300g
uniprot id: Q6BXG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284592:DEHA2E07832g
gene id: 284592:DEHA2E07832g
uniprot id: Q6BQ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284592:DEHA2E00550g
gene id: 284592:DEHA2E00550g
uniprot id: Q6BR19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2F06820g
gene id: 284592:DEHA2F06820g
uniprot id: Q6BMB5
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

284592:DEHA2E18656g
gene id: 284592:DEHA2E18656g
uniprot id: Q6BNV7
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

284592:DEHA2A02398g
gene id: 284592:DEHA2A02398g
uniprot id: Q6BZC6
names: Similarity
messages: Belongs to the PhyH family.

284592:DEHA2D16632g
gene id: 284592:DEHA2D16632g
uniprot id: Q6BRG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.

284592:DEHA2A10868g
gene id: 284592:DEHA2A10868g
uniprot id: B5RSU6
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

284592:DEHA2D17644g
gene id: 284592:DEHA2D17644g
uniprot id: B5RTK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

284592:DEHA2G22396g
gene id: 284592:DEHA2G22396g
uniprot id: Q6BH03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the peroxisomal translocation machinery.
messages: Peroxisome membrane

284592:DEHA2C03454g
gene id: 284592:DEHA2C03454g
uniprot id: Q6BVD6
names: Similarity
messages: Belongs to the amidase family.

284592:DEHA2F26554g
gene id: 284592:DEHA2F26554g
uniprot id: Q6BJX8
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

284592:DEHA2A09856g
gene id: 284592:DEHA2A09856g
uniprot id: Q6BYF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

284592:DEHA2C14036g
gene id: 284592:DEHA2C14036g
uniprot id: Q6BU30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG12 family.
messages: Forms a conjugate with ATG5.
messages: Preautophagosomal structure membrane
messages: Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate functions as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).

284592:DEHA2F06380g
gene id: 284592:DEHA2F06380g
uniprot id: Q6BMD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: May be involved in vacuolar sorting and osmoregulation.
messages: Vacuole membrane

284592:DEHA2G23144g
gene id: 284592:DEHA2G23144g
uniprot id: Q6BGX3
names: Similarity
messages: Belongs to the peptidase S9B family.

284592:DEHA2B14080g
gene id: 284592:DEHA2B14080g
uniprot id: B5RSV9
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2B06424g
gene id: 284592:DEHA2B06424g
uniprot id: Q6BX30
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

284592:DEHA2E14454g
gene id: 284592:DEHA2E14454g
uniprot id: Q6BPD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SPCS3 family.
messages: Component of the signal peptidase complex (SPC) composed of a catalytic subunit SEC11 and three accessory subunits SPC1, SPC2 and SPC3 (By similarity). The complex induces a local thinning of the ER membrane which is used to measure the length of the signal peptide (SP) h-region of protein substrates. This ensures the selectivity of the complex towards h-regions shorter than 18-20 amino acids (By similarity). SPC associates with the translocon complex (By similarity).
messages: Endoplasmic reticulum membrane
messages: Essential component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Essential for the SPC catalytic activity, possibly by stabilizing and positioning the active center of the complex close to the lumenal surface. Essential for viability.

284592:DEHA2G08228g
gene id: 284592:DEHA2G08228g
uniprot id: Q6BIR5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284592:DEHA2G20372g
gene id: 284592:DEHA2G20372g
uniprot id: Q6BH93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
messages: Associates in the nucleolus with the 60S and pre-60S ribosomal subunits.
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284592:DEHA2B05126g
gene id: 284592:DEHA2B05126g
uniprot id: Q6BX84
names: Similarity
messages: Belongs to the acetyltransferase family. GNA1 subfamily.

284592:DEHA2B00308g
gene id: 284592:DEHA2B00308g
uniprot id: Q6BXT9
names: Similarity
messages: Belongs to the asparaginase 1 family.

284592:DEHA2F15796g
gene id: 284592:DEHA2F15796g
uniprot id: Q6BL75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP11 family.
messages: Mitochondrion

284592:DEHA2B06006g
gene id: 284592:DEHA2B06006g
uniprot id: Q6BX47
names: Similarity
messages: Belongs to the MIP18 family.

284592:DEHA2A01298g
gene id: 284592:DEHA2A01298g
uniprot id: Q6BZH4
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

284592:DEHA2B13838g
gene id: 284592:DEHA2B13838g
uniprot id: Q6BW71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

284592:DEHA2F00462g
gene id: 284592:DEHA2F00462g
uniprot id: Q6BN39
names: Similarity
messages: Belongs to the alkaline phosphatase family.

284592:DEHA2F13992g
gene id: 284592:DEHA2F13992g
uniprot id: Q6BLE9
names: Similarity
messages: Belongs to the hexokinase family.

284592:DEHA2F06842g
gene id: 284592:DEHA2F06842g
uniprot id: Q6BMB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

284592:DEHA2B09570g
gene id: 284592:DEHA2B09570g
uniprot id: Q6BWQ2
names: Similarity
messages: Belongs to the syntaxin family.

284592:DEHA2F00572g
gene id: 284592:DEHA2F00572g
uniprot id: Q6BN36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2C05522g
gene id: 284592:DEHA2C05522g
uniprot id: Q6BV42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NPC2 family.
messages: Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
messages: Monomer.

284592:DEHA2B01782g
gene id: 284592:DEHA2B01782g
uniprot id: Q6BXM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ING family.
messages: Nucleus

284592:DEHA2F24222g
gene id: 284592:DEHA2F24222g
uniprot id: B5RUM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Sterol O-acyltransferase that catalyzes the formation of stery esters.

284592:DEHA2F25872g
gene id: 284592:DEHA2F25872g
uniprot id: Q6BK07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CLASP family.
messages: Interacts with microtubules.
messages: Microtubule binding protein that promotes the stabilization of dynamic microtubules. Required for mitotic spindle formation (By similarity).
messages: Nucleus
messages: cytoskeleton
messages: spindle

284592:DEHA2A02794g
gene id: 284592:DEHA2A02794g
uniprot id: Q6BZA7
names: Similarity
messages: Belongs to the MSOX/MTOX family.

284592:DEHA2F13156g
gene id: 284592:DEHA2F13156g
uniprot id: Q6BLI5
names: Function
names: Similarity
messages: Belongs to the GPI family.
messages: In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.

284592:DEHA2F08492g
gene id: 284592:DEHA2F08492g
uniprot id: Q6BM40
names: Similarity
messages: Belongs to the CCDC124 family.

284592:DEHA2E15510g
gene id: 284592:DEHA2E15510g
uniprot id: B5RU21
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: GTPase-activating protein for the ADP ribosylation factor family.

284592:DEHA2C04708g
gene id: 284592:DEHA2C04708g
uniprot id: Q6BV78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

284592:DEHA2C07084g
gene id: 284592:DEHA2C07084g
uniprot id: Q6BUX9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PROPPIN family.
messages: Cytoplasmic vesicle membrane
messages: Involved in mitochondrial or peroxisomal functions and amino acid signaling pathways.
messages: May contain a beta-propeller domain involved in specific binding to phosphatidylinositol 3,5-bisphosphate (PIP2), leading to the association of the protein to the membrane.
messages: Vacuole membrane

284592:DEHA2A02662g
gene id: 284592:DEHA2A02662g
uniprot id: Q6BZB4
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F10406g
gene id: 284592:DEHA2F10406g
uniprot id: Q6BLV4
names: Similarity
messages: Belongs to the SF3B5 family.

284592:DEHA2G23540g
gene id: 284592:DEHA2G23540g
uniprot id: Q6BGV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

284592:DEHA2F20768g
gene id: 284592:DEHA2F20768g
uniprot id: Q6BKM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Nuclear serine protease which mediates apoptosis.
messages: Nucleus

284592:DEHA2G04444g
gene id: 284592:DEHA2G04444g
uniprot id: Q6BJ82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

284592:DEHA2C14586g
gene id: 284592:DEHA2C14586g
uniprot id: Q6BU02
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

284592:DEHA2B08382g
gene id: 284592:DEHA2B08382g
uniprot id: Q6BWU8
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

284592:DEHA2D11968g
gene id: 284592:DEHA2D11968g
uniprot id: Q6BS31
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

284592:DEHA2E10318g
gene id: 284592:DEHA2E10318g
uniprot id: Q6BPW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GcvT family. CAF17 subfamily.
messages: Mitochondrion

284592:DEHA2B10560g
gene id: 284592:DEHA2B10560g
uniprot id: Q6BWK7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2G16082g
gene id: 284592:DEHA2G16082g
uniprot id: Q6BHS8
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

284592:DEHA2D17842g
gene id: 284592:DEHA2D17842g
uniprot id: Q6BRA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

284592:DEHA2B04642g
gene id: 284592:DEHA2B04642g
uniprot id: Q6BXA5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

284592:DEHA2C17226g
gene id: 284592:DEHA2C17226g
uniprot id: Q6BTN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM54 family.
messages: Component of the TIM22 complex, whose core is composed of TIM22 and TIM54, associated with the 70 kDa heterohexamer composed of TIM9 and TIM10 (or TIM8 and TIM13).
messages: Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
messages: Mitochondrion inner membrane

284592:DEHA2B08118g
gene id: 284592:DEHA2B08118g
uniprot id: Q6BWV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytoskeleton

284592:DEHA2E09064g
gene id: 284592:DEHA2E09064g
uniprot id: Q6BQ18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity).
messages: Nucleus

284592:DEHA2G08668g
gene id: 284592:DEHA2G08668g
uniprot id: Q6BIP7
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

284592:DEHA2A06424g
gene id: 284592:DEHA2A06424g
uniprot id: B5RSR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

284592:DEHA2E07920g
gene id: 284592:DEHA2E07920g
uniprot id: Q6BQ66
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

284592:DEHA2E04444g
gene id: 284592:DEHA2E04444g
uniprot id: Q6BQK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Involved in the maintenance of ribosomal (rDNA). Required for efficient fork arrest at the replicaion fork barrier within rDNA. Involved in the maintenance of mitochondrial (mtDNA). Required to maintain mtDNA under conditions that introduce dsDNA breaks in mtDNA, either preventing or repairing dsDNA breaks. May inhibit replication progression to allow time for repair. May have a general role in chromosomal replication by affecting Okazaki fragment maturation. May have a role in conjunction with DNA2 helicase/nuclease in 5'-flap extension during Okazaki fragment processing.
messages: Mitochondrion
messages: Monomer. Interacts with telomerase.
messages: Nucleus

284592:DEHA2E03322g
gene id: 284592:DEHA2E03322g
uniprot id: B5RTT5
names: Similarity
messages: Belongs to the peptidase C19 family.

284592:DEHA2E01210g
gene id: 284592:DEHA2E01210g
uniprot id: Q6BQZ2
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E05434g
gene id: 284592:DEHA2E05434g
uniprot id: Q6BQG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EST3 family.
messages: Component of the telomerase complex involved in telomere replication. Stimulates RNA/DNA heteroduplex unwinding which favors the telomere replication by the telomerase (By similarity).
messages: Component of the telomerase complex.
messages: Nucleus
messages: telomere

284592:DEHA2B06050g
gene id: 284592:DEHA2B06050g
uniprot id: Q6BX45
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. FKBP1 subfamily.
messages: Cytoplasm
messages: Inhibited by both FK506 and rapamycin.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

284592:DEHA2D16940g
gene id: 284592:DEHA2D16940g
uniprot id: B5RTJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

284592:DEHA2C02486g
gene id: 284592:DEHA2C02486g
uniprot id: Q6BVI1
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

284592:DEHA2G13486g
gene id: 284592:DEHA2G13486g
uniprot id: Q6BI47
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

284592:DEHA2E15994g
gene id: 284592:DEHA2E15994g
uniprot id: Q6BP72
names: Similarity
messages: Belongs to the JHDM3 histone demethylase family.

284592:DEHA2D12496g
gene id: 284592:DEHA2D12496g
uniprot id: Q6BS05
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

284592:DEHA2B12787g
gene id: 284592:DEHA2B12787g
uniprot id: B5RSZ5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

284592:DEHA2C02816g
gene id: 284592:DEHA2C02816g
uniprot id: Q6BVG7
names: Similarity
messages: Belongs to the PP2C family.

284592:DEHA2D01914g
gene id: 284592:DEHA2D01914g
uniprot id: Q6BTB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284592:DEHA2E21604g
gene id: 284592:DEHA2E21604g
uniprot id: Q6BNH8
names: Similarity
messages: Belongs to the acetolactate synthase small subunit family.

284592:DEHA2G24002g
gene id: 284592:DEHA2G24002g
uniprot id: Q6BGT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
messages: Membrane

284592:DEHA2G19866g
gene id: 284592:DEHA2G19866g
uniprot id: Q6BHB4
names: Function
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.
messages: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

284592:DEHA2C05368g
gene id: 284592:DEHA2C05368g
uniprot id: Q6BV48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

284592:DEHA2G09768g
gene id: 284592:DEHA2G09768g
uniprot id: Q6BIK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

284592:DEHA2B06556g
gene id: 284592:DEHA2B06556g
uniprot id: Q6BX25
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

284592:DEHA2G03520g
gene id: 284592:DEHA2G03520g
uniprot id: B5RV26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

284592:DEHA2C17182g
gene id: 284592:DEHA2C17182g
uniprot id: Q6BTN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

284592:DEHA2G18414g
gene id: 284592:DEHA2G18414g
uniprot id: Q6BHI0
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

284592:DEHA2F14608g
gene id: 284592:DEHA2F14608g
uniprot id: Q6BLC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPI1/TEX10 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.
messages: Nucleus

284592:DEHA2G00946g
gene id: 284592:DEHA2G00946g
uniprot id: Q6BJP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

284592:DEHA2B10384g
gene id: 284592:DEHA2B10384g
uniprot id: Q6BWL5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

284592:DEHA2C12936g
gene id: 284592:DEHA2C12936g
uniprot id: Q6BU81
names: Similarity
messages: Belongs to the peptidase C19 family.

284592:DEHA2A10450g
gene id: 284592:DEHA2A10450g
uniprot id: Q6BYD2
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2F23166g
gene id: 284592:DEHA2F23166g
uniprot id: Q6BKC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

284592:DEHA2B03718g
gene id: 284592:DEHA2B03718g
uniprot id: Q6BXE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Although related to the peptidase M24 family, this protein lacks conserved active site residues suggesting that it may lack peptidase activity.
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity).
messages: Forms a stable heterodimer with POB3. The SPT16-POB3 dimer weakly associates with multiple molecules of NHP6 to form the FACT complex (By similarity).
messages: Nucleus

284592:DEHA2B10626g
gene id: 284592:DEHA2B10626g
uniprot id: Q6BWK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GET2 family.
messages: Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.

284592:DEHA2E11198g
gene id: 284592:DEHA2E11198g
uniprot id: Q6BPS5
names: Function
names: Similarity
messages: Belongs to the cyclin family.
messages: G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition.

284592:DEHA2E09372g
gene id: 284592:DEHA2E09372g
uniprot id: Q6BQ04
names: Similarity
messages: Belongs to the COG2 family.

284592:DEHA2D07722g
gene id: 284592:DEHA2D07722g
uniprot id: Q6BSM4
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

284592:DEHA2E08712g
gene id: 284592:DEHA2E08712g
uniprot id: Q6BQ34
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: By homology to other fibrillarins, some or all of the N-terminal domain arginines are modified to asymmetric dimethylarginine (DMA).
messages: Component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles that contain SNU13, NOP1, SIK1/NOP56 and NOP58, plus a guide RNA.
messages: S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (By similarity).
messages: nucleolus

284592:DEHA2D11396g
gene id: 284592:DEHA2D11396g
uniprot id: Q6BS59
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

284592:DEHA2F12276g
gene id: 284592:DEHA2F12276g
uniprot id: Q6BLM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

284592:DEHA2G03146g
gene id: 284592:DEHA2G03146g
uniprot id: Q6BJD9
names: Function
messages: Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.

284592:DEHA2C06952g
gene id: 284592:DEHA2C06952g
uniprot id: Q6BUY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2D07964g
gene id: 284592:DEHA2D07964g
uniprot id: B5RTF4
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the activation of alpha-aminoadipate by ATP-dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH. The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate.

284592:DEHA2C17820g
gene id: 284592:DEHA2C17820g
uniprot id: Q6BTK1
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E12584g
gene id: 284592:DEHA2E12584g
uniprot id: Q6BPL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHE3 family.
messages: Endoplasmic reticulum membrane
messages: RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Required for the delivery of cortical endoplasmic reticulum into the emerging bud.

284592:DEHA2A01232g
gene id: 284592:DEHA2A01232g
uniprot id: Q6BZH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

284592:DEHA2F10736g
gene id: 284592:DEHA2F10736g
uniprot id: Q6BLU1
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the NAGSA dehydrogenase family.
messages: In the N-terminal section; belongs to the acetylglutamate kinase family.
messages: Mitochondrion

284592:DEHA2F03938g
gene id: 284592:DEHA2F03938g
uniprot id: Q6BMN4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

284592:DEHA2G11022g
gene id: 284592:DEHA2G11022g
uniprot id: Q6BIE9
names: Similarity
messages: Belongs to the UPF0357 family.

284592:DEHA2D10472g
gene id: 284592:DEHA2D10472g
uniprot id: Q6BS99
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

284592:DEHA2G13904g
gene id: 284592:DEHA2G13904g
uniprot id: Q6BI27
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

284592:DEHA2D06930g
gene id: 284592:DEHA2D06930g
uniprot id: B5RTE1
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

284592:DEHA2D03828g
gene id: 284592:DEHA2D03828g
uniprot id: Q6BT37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RGI1 family.
messages: Cell membrane
messages: Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions.

284592:DEHA2A12606g
gene id: 284592:DEHA2A12606g
uniprot id: B5RSV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Nucleus

284592:DEHA2C07898g
gene id: 284592:DEHA2C07898g
uniprot id: Q6BUU6
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2B15994g
gene id: 284592:DEHA2B15994g
uniprot id: Q6BVX3
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C05346g
gene id: 284592:DEHA2C05346g
uniprot id: Q6BV49
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

284592:DEHA2C08712g
gene id: 284592:DEHA2C08712g
uniprot id: Q6BUR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

284592:DEHA2B03410g
gene id: 284592:DEHA2B03410g
uniprot id: Q6BXF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).

284592:DEHA2G18062g
gene id: 284592:DEHA2G18062g
uniprot id: Q6BHJ6
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

284592:DEHA2E21978g
gene id: 284592:DEHA2E21978g
uniprot id: Q6BNG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

284592:DEHA2F13068g
gene id: 284592:DEHA2F13068g
uniprot id: Q6BLI9
names: Similarity
messages: Belongs to the aldo/keto reductase family.

284592:DEHA2F01848g
gene id: 284592:DEHA2F01848g
uniprot id: Q6BMX6
names: Similarity
messages: Belongs to the MAK16 family.

284592:DEHA2E19294g
gene id: 284592:DEHA2E19294g
uniprot id: Q6BNS6
names: Similarity
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.

284592:DEHA2D10516g
gene id: 284592:DEHA2D10516g
uniprot id: Q6BS98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Endoplasmic reticulum membrane
messages: Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER (By similarity).

284592:DEHA2E14036g
gene id: 284592:DEHA2E14036g
uniprot id: Q6BPF4
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

284592:DEHA2F08712g
gene id: 284592:DEHA2F08712g
uniprot id: Q6BM30
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

284592:DEHA2D03850g
gene id: 284592:DEHA2D03850g
uniprot id: Q6BT36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: nucleolus

284592:DEHA2C13794g
gene id: 284592:DEHA2C13794g
uniprot id: Q6BU41
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2G03234g
gene id: 284592:DEHA2G03234g
uniprot id: Q6BJD5
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E05038g
gene id: 284592:DEHA2E05038g
uniprot id: Q6BQI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

284592:DEHA2D18216g
gene id: 284592:DEHA2D18216g
uniprot id: B5RTL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion

284592:DEHA2G05280g
gene id: 284592:DEHA2G05280g
uniprot id: F2Z5X8
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

284592:DEHA2F08360g
gene id: 284592:DEHA2F08360g
uniprot id: Q6BM47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

284592:DEHA2C01298g
gene id: 284592:DEHA2C01298g
uniprot id: Q6BVN2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

284592:DEHA2A03520g
gene id: 284592:DEHA2A03520g
uniprot id: Q6BZ74
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2D10340g
gene id: 284592:DEHA2D10340g
uniprot id: Q6BSA5
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

284592:DEHA2F06424g
gene id: 284592:DEHA2F06424g
uniprot id: Q6BMD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

284592:DEHA2F17952g
gene id: 284592:DEHA2F17952g
uniprot id: Q6BKY1
names: Similarity
messages: Belongs to the glutaredoxin family.

284592:DEHA2G05368g
gene id: 284592:DEHA2G05368g
uniprot id: Q6BJ42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2D02618g
gene id: 284592:DEHA2D02618g
uniprot id: Q6BT88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NCBP2 family.
messages: Nucleus

284592:DEHA2G06842g
gene id: 284592:DEHA2G06842g
uniprot id: Q6BIX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: Required for pre-18S rRNA processing. May bind microtubules (By similarity).
messages: nucleolus

284592:DEHA2C11616g
gene id: 284592:DEHA2C11616g
uniprot id: W0TYR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWC4 family.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

284592:DEHA2E11792g
gene id: 284592:DEHA2E11792g
uniprot id: Q6BPP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

284592:DEHA2A13640g
gene id: 284592:DEHA2A13640g
uniprot id: Q6BXZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

284592:DEHA2B04928g
gene id: 284592:DEHA2B04928g
uniprot id: Q6BUU5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

284592:DEHA2G13596g
gene id: 284592:DEHA2G13596g
uniprot id: Q6BI42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284592:DEHA2F24882g
gene id: 284592:DEHA2F24882g
uniprot id: Q6BK50
names: Similarity
messages: Belongs to the peptidase C19 family.

284592:DEHA2D16830g
gene id: 284592:DEHA2D16830g
uniprot id: Q6BRF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMA20 family.
messages: Cytoplasm
messages: Involved in translation.

284592:DEHA2G05698g
gene id: 284592:DEHA2G05698g
uniprot id: Q6BJ27
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

284592:DEHA2A01870g
gene id: 284592:DEHA2A01870g
uniprot id: Q6BZF0
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

284592:DEHA2D05500g
gene id: 284592:DEHA2D05500g
uniprot id: Q6BSW3
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2E21956g
gene id: 284592:DEHA2E21956g
uniprot id: Q6BNG4
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

284592:DEHA2F23320g
gene id: 284592:DEHA2F23320g
uniprot id: Q6BKB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284592:DEHA2E21054g
gene id: 284592:DEHA2E21054g
uniprot id: Q6BNK1
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

284592:DEHA2G12386g
gene id: 284592:DEHA2G12386g
uniprot id: Q6BI99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Part of a complex that contains SEC61, SEC62, SEC63, SEC66 and SEC72.
messages: Required for preprotein translocation.

284592:DEHA2C17248g
gene id: 284592:DEHA2C17248g
uniprot id: Q6BTN0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

284592:DEHA2F09240g
gene id: 284592:DEHA2F09240g
uniprot id: Q6BM09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferric reductase (FRE) family. AIM14 subfamily.
messages: Membrane
messages: Probable cell surface metalloreductase. May be involved in iron or copper homeostasis (By similarity).

284592:DEHA2G18260g
gene id: 284592:DEHA2G18260g
uniprot id: Q6BHI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284592:DEHA2F03102g
gene id: 284592:DEHA2F03102g
uniprot id: Q6BMS0
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

284592:DEHA2E15356g
gene id: 284592:DEHA2E15356g
uniprot id: Q6BP97
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. PFA5 subfamily.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

284592:DEHA2F20240g
gene id: 284592:DEHA2F20240g
uniprot id: Q6BKP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EXO5 family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Mitochondrion
messages: Monomer.
messages: Single strand DNA specific 5' exonuclease involved in mitochondrial DNA replication and recombination. Releases dinucleotides as main products of catalysis. Has the capacity to slide across 5'double-stranded DNA or 5'RNA sequences and resumes cutting two nucleotides downstream of the double-stranded-to-single-stranded junction or RNA-to-DNA junction, respectively (By similarity).

284592:DEHA2G00792g
gene id: 284592:DEHA2G00792g
uniprot id: Q6BJQ3
names: Similarity
messages: Belongs to the importin alpha family.

284592:DEHA2B05478g
gene id: 284592:DEHA2B05478g
uniprot id: Q6BX71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.
messages: Homodimer.
messages: Mitochondrion matrix

284592:DEHA2G06622g
gene id: 284592:DEHA2G06622g
uniprot id: Q6BIY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

284592:DEHA2F16918g
gene id: 284592:DEHA2F16918g
uniprot id: Q6BL25
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

284592:DEHA2G01628g
gene id: 284592:DEHA2G01628g
uniprot id: Q6BJL0
names: Function
messages: Delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides. Required for the formation of the di-unsaturated sphingoid base (E,E)-sphinga-4,8-dienine during glucosylceramide (GluCer) biosynthesis.

284592:DEHA2G23276g
gene id: 284592:DEHA2G23276g
uniprot id: Q6BGW7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

284592:DEHA2G18106g
gene id: 284592:DEHA2G18106g
uniprot id: Q6BHJ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer; composed of 3 copies of TIM9 and 3 copies of TIM10, named soluble 70 kDa complex. Associates directly with the TIM22 complex, whose core is composed of TIM22 and TIM54. Interacts with the transmembrane regions of multi-pass transmembrane proteins in transit (By similarity).
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. However, during the transit of TIM10 from cytoplasm into mitochondrion, the Cys residues probably coordinate zinc, thereby preventing folding and allowing its transfer across mitochondrial outer membrane (By similarity).

284592:DEHA2B10736g
gene id: 284592:DEHA2B10736g
uniprot id: Q6BWJ9
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G22044g
gene id: 284592:DEHA2G22044g
uniprot id: Q6BH19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus

284592:DEHA2D03520g
gene id: 284592:DEHA2D03520g
uniprot id: Q6BT49
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

284592:DEHA2G14894g
gene id: 284592:DEHA2G14894g
uniprot id: Q6BHY4
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G03740g
gene id: 284592:DEHA2G03740g
uniprot id: Q6BJB3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

284592:DEHA2C13222g
gene id: 284592:DEHA2C13222g
uniprot id: Q6BU66
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2E11044g
gene id: 284592:DEHA2E11044g
uniprot id: Q6BPT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: Nucleus

284592:DEHA2G08338g
gene id: 284592:DEHA2G08338g
uniprot id: Q6BIR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat SEC13 family.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
messages: Endoplasmic reticulum membrane
messages: The COPII coat is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex, and the protein SAR1. Component of the nuclear pore complex (NPC). NPC constitutes the exclusive means of nucleocytoplasmic transport. NPCs allow the passive diffusion of ions and small molecules and the active, nuclear transport receptor-mediated bidirectional transport of macromolecules such as proteins, RNAs, ribonucleoparticles (RNPs), and ribosomal subunits across the nuclear envelope. Due to its 8-fold rotational symmetry, all subunits are present with 8 copies or multiples thereof.
messages: nuclear pore complex

284592:DEHA2F03960g
gene id: 284592:DEHA2F03960g
uniprot id: Q6BMN3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

284592:DEHA2C17666g
gene id: 284592:DEHA2C17666g
uniprot id: Q6BTK7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

284592:DEHA2G19492g
gene id: 284592:DEHA2G19492g
uniprot id: Q6BHD1
names: Similarity
messages: Belongs to the DSD1 family.

284592:DEHA2E06930g
gene id: 284592:DEHA2E06930g
uniprot id: Q6BQA9
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2E21626g
gene id: 284592:DEHA2E21626g
uniprot id: Q6BNH7
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.

284592:DEHA2C09306g
gene id: 284592:DEHA2C09306g
uniprot id: Q6BUN7
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
messages: Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

284592:DEHA2F02618g
gene id: 284592:DEHA2F02618g
uniprot id: Q6BMU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

284592:DEHA2C02684g
gene id: 284592:DEHA2C02684g
uniprot id: Q6BVH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Required for vacuolar assembly and vacuolar traffic.
messages: Vacuole

284592:DEHA2B06490g
gene id: 284592:DEHA2B06490g
uniprot id: Q6BX28
names: Similarity
messages: Belongs to the Rho GDI family.

284592:DEHA2A01760g
gene id: 284592:DEHA2A01760g
uniprot id: Q6BZF4
names: Similarity
messages: Belongs to the cyclin family.

284592:DEHA2G12584g
gene id: 284592:DEHA2G12584g
uniprot id: Q6BI89
names: Similarity
messages: Belongs to the 14-3-3 family.

284592:DEHA2G20724g
gene id: 284592:DEHA2G20724g
uniprot id: Q6BH78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus

284592:DEHA2D14564g
gene id: 284592:DEHA2D14564g
uniprot id: Q6BRQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

284592:DEHA2D05720g
gene id: 284592:DEHA2D05720g
uniprot id: Q6BSV5
names: Similarity
messages: Belongs to the cytochrome b5 family.

284592:DEHA2D12606g
gene id: 284592:DEHA2D12606g
uniprot id: Q6BS00
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

284592:DEHA2F07018g
gene id: 284592:DEHA2F07018g
uniprot id: Q6BMA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. GEP3 subfamily.
messages: May be involved in the mitochondrial lipid metabolism.
messages: Mitochondrion

284592:DEHA2E17864g
gene id: 284592:DEHA2E17864g
uniprot id: Q6BNZ1
names: Subcellular Location Annotation
messages: nucleolus

284592:DEHA2E10428g
gene id: 284592:DEHA2E10428g
uniprot id: Q6BPW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

284592:DEHA2G14476g
gene id: 284592:DEHA2G14476g
uniprot id: Q6BI01
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

284592:DEHA2D02552g
gene id: 284592:DEHA2D02552g
uniprot id: Q6BT91
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

284592:DEHA2D15950g
gene id: 284592:DEHA2D15950g
uniprot id: Q6BRJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

284592:DEHA2E18854g
gene id: 284592:DEHA2E18854g
uniprot id: Q6BNV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2D06226g
gene id: 284592:DEHA2D06226g
uniprot id: Q6BSU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSH4 family.
messages: Components of the endosome-vacuole trafficking pathway that regulates nutrient transport. May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane (By similarity).
messages: Endosome membrane
messages: Vacuole membrane

284592:DEHA2G08998g
gene id: 284592:DEHA2G08998g
uniprot id: Q6BIN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMN1 family.
messages: Cytoplasm
messages: Negative regulator of the mitotic exit network (MEN), required for multiple cell cycle checkpoints. Required for daughter cell separation and chromosome stability. Involved in copper sensitivity.
messages: Nucleus

284592:DEHA2F16874g
gene id: 284592:DEHA2F16874g
uniprot id: Q6BL27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DASH complex DAD1 family.
messages: Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
messages: Nucleus
messages: The DASH complex oligomerizes to form rings that encircle the microtubules.
messages: kinetochore
messages: spindle

284592:DEHA2A01540g
gene id: 284592:DEHA2A01540g
uniprot id: Q6BZG4
names: Similarity
messages: In the C-terminal section; belongs to the NAD synthetase family.

284592:DEHA2G10076g
gene id: 284592:DEHA2G10076g
uniprot id: Q6BII6
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

284592:DEHA2B03938g
gene id: 284592:DEHA2B03938g
uniprot id: Q6BXD5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

284592:DEHA2E04224g
gene id: 284592:DEHA2E04224g
uniprot id: Q6BQL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2B09438g
gene id: 284592:DEHA2B09438g
uniprot id: Q6BWQ8
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2B01210g
gene id: 284592:DEHA2B01210g
uniprot id: Q6BXQ0
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

284592:DEHA2G07502g
gene id: 284592:DEHA2G07502g
uniprot id: B5RV50
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

284592:DEHA2D04004g
gene id: 284592:DEHA2D04004g
uniprot id: Q6BT29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 4 family.
messages: Membrane

284592:DEHA2E23628g
gene id: 284592:DEHA2E23628g
uniprot id: Q6BN93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

284592:DEHA2F23628g
gene id: 284592:DEHA2F23628g
uniprot id: Q6BKA1
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

284592:DEHA2B15466g
gene id: 284592:DEHA2B15466g
uniprot id: Q6BVZ7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.
messages: Cytoplasm

284592:DEHA2B02156g
gene id: 284592:DEHA2B02156g
uniprot id: Q6BXK8
names: Similarity
messages: Belongs to the SGT1 family.

284592:DEHA2B02332g
gene id: 284592:DEHA2B02332g
uniprot id: B5RT29
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G20900g
gene id: 284592:DEHA2G20900g
uniprot id: Q6BH70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

284592:DEHA2D16984g
gene id: 284592:DEHA2D16984g
uniprot id: B5RTJ8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

284592:DEHA2E15664g
gene id: 284592:DEHA2E15664g
uniprot id: Q6BP86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPS2 family.
messages: Cell membrane
messages: Membrane

284592:DEHA2C07612g
gene id: 284592:DEHA2C07612g
uniprot id: Q6BUV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

284592:DEHA2A02244g
gene id: 284592:DEHA2A02244g
uniprot id: B5RSP3
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

284592:DEHA2B02926g
gene id: 284592:DEHA2B02926g
uniprot id: Q6BXH7
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2F21758g
gene id: 284592:DEHA2F21758g
uniprot id: Q6BKI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

284592:DEHA2D02244g
gene id: 284592:DEHA2D02244g
uniprot id: Q6BTA5
names: Similarity
messages: Belongs to the peptidase S10 family.

284592:DEHA2D18546g
gene id: 284592:DEHA2D18546g
uniprot id: B5RTL9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.

284592:DEHA2G11572g
gene id: 284592:DEHA2G11572g
uniprot id: B5RUQ9
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D01210g
gene id: 284592:DEHA2D01210g
uniprot id: Q6BTE9
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E13090g
gene id: 284592:DEHA2E13090g
uniprot id: Q6BPJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates 60S ribosomal protein L42.

284592:DEHA2A13794g
gene id: 284592:DEHA2A13794g
uniprot id: Q6BXZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

284592:DEHA2E04554g
gene id: 284592:DEHA2E04554g
uniprot id: Q6BQK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic12 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

284592:DEHA2A06204g
gene id: 284592:DEHA2A06204g
uniprot id: B5RSR1
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

284592:DEHA2D09592g
gene id: 284592:DEHA2D09592g
uniprot id: Q6BSD8
names: Similarity
names: Subunit
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.
messages: Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.

284592:DEHA2A05478g
gene id: 284592:DEHA2A05478g
uniprot id: B5RSQ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YAF9 family.
messages: Component of the SWR1 chromatin-remodeling complex and of the NuA4 histone acetyltransferase complex.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for an H2A variant leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised.
messages: Cytoplasm
messages: Nucleus
messages: The coiled-coil domain is required for assembly into the NuA4 complex.

284592:DEHA2D03696g
gene id: 284592:DEHA2D03696g
uniprot id: Q6BT42
names: Function
names: Similarity
messages: Belongs to the WD repeat DSE1 family.
messages: Involved in cell wall metabolism and required for the separation of the mother and daughter cells.

284592:DEHA2C10494g
gene id: 284592:DEHA2C10494g
uniprot id: Q6BUI0
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2A11814g
gene id: 284592:DEHA2A11814g
uniprot id: Q6BY76
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.

284592:DEHA2G19668g
gene id: 284592:DEHA2G19668g
uniprot id: Q6BHC3
names: Similarity
messages: Belongs to the phospholipid scramblase family.

284592:DEHA2G19184g
gene id: 284592:DEHA2G19184g
uniprot id: Q6BHE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

284592:DEHA2E00594g
gene id: 284592:DEHA2E00594g
uniprot id: Q6BR16
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2A02024g
gene id: 284592:DEHA2A02024g
uniprot id: Q6BZE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNN1/MNT family.
messages: Golgi apparatus membrane
messages: Membrane

284592:DEHA2C02244g
gene id: 284592:DEHA2C02244g
uniprot id: Q6BVJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

284592:DEHA2B02112g
gene id: 284592:DEHA2B02112g
uniprot id: Q6BXL0
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G04642g
gene id: 284592:DEHA2G04642g
uniprot id: Q6BJ74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM31/MDM32 family.
messages: Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.
messages: Mitochondrion inner membrane

284592:DEHA2E05896g
gene id: 284592:DEHA2E05896g
uniprot id: Q6BQE1
names: Similarity
messages: Belongs to the PDCD5 family.

284592:DEHA2B16258g
gene id: 284592:DEHA2B16258g
uniprot id: Q6BVW1
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

284592:DEHA2B15796g
gene id: 284592:DEHA2B15796g
uniprot id: Q6BVY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Membrane

284592:DEHA2E21428g
gene id: 284592:DEHA2E21428g
uniprot id: B5RU50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2B08580g
gene id: 284592:DEHA2B08580g
uniprot id: Q6BWU0
names: Similarity
messages: Belongs to the ATG101 family.

284592:DEHA2C16302g
gene id: 284592:DEHA2C16302g
uniprot id: Q6BTS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2A00814g
gene id: 284592:DEHA2A00814g
uniprot id: Q6BZJ6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

284592:DEHA2E10560g
gene id: 284592:DEHA2E10560g
uniprot id: Q6BPV4
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

284592:DEHA2E19624g
gene id: 284592:DEHA2E19624g
uniprot id: Q6BNR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I LYR family.
messages: Mitochondrion inner membrane

284592:DEHA2D03256g
gene id: 284592:DEHA2D03256g
uniprot id: Q6BT61
names: Similarity
messages: Belongs to the PHAF1 family.

284592:DEHA2G18436g
gene id: 284592:DEHA2G18436g
uniprot id: Q6BHH9
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

284592:DEHA2D17380g
gene id: 284592:DEHA2D17380g
uniprot id: Q6BRC7
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F18678g
gene id: 284592:DEHA2F18678g
uniprot id: Q6BKW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

284592:DEHA2G24728g
gene id: 284592:DEHA2G24728g
uniprot id: B5RV03
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G14168g
gene id: 284592:DEHA2G14168g
uniprot id: Q6BI15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

284592:DEHA2D17248g
gene id: 284592:DEHA2D17248g
uniprot id: Q6BRD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

284592:DEHA2C11110g
gene id: 284592:DEHA2C11110g
uniprot id: B5RT97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus

284592:DEHA2F09372g
gene id: 284592:DEHA2F09372g
uniprot id: Q6BM03
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

284592:DEHA2B14102g
gene id: 284592:DEHA2B14102g
uniprot id: Q6BW61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKN1/KRE6 family.
messages: Membrane

284592:DEHA2E12760g
gene id: 284592:DEHA2E12760g
uniprot id: Q6BPK9
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

284592:DEHA2D11682g
gene id: 284592:DEHA2D11682g
uniprot id: Q6BS45
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

284592:DEHA2E03982g
gene id: 284592:DEHA2E03982g
uniprot id: B5RTU5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

284592:DEHA2F22880g
gene id: 284592:DEHA2F22880g
uniprot id: Q6BKD4
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

284592:DEHA2D17622g
gene id: 284592:DEHA2D17622g
uniprot id: Q6BRB7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
messages: Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.

284592:DEHA2E23716g
gene id: 284592:DEHA2E23716g
uniprot id: Q6BN89
names: Similarity
messages: Belongs to the AB hydrolase superfamily. MetX family.

284592:DEHA2G17028g
gene id: 284592:DEHA2G17028g
uniprot id: Q6BHP2
names: Similarity
messages: Belongs to the RNase PH family.

284592:DEHA2G10890g
gene id: 284592:DEHA2G10890g
uniprot id: Q6BIF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May act as a specificity factor that binds precursor rRNAs and tethers the enzymes that carry out the early 5' to 3' exonucleolytic reactions that generate the mature rRNAs (By similarity).
messages: nucleolus

284592:DEHA2C14916g
gene id: 284592:DEHA2C14916g
uniprot id: Q6BTY7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

284592:DEHA2F09108g
gene id: 284592:DEHA2F09108g
uniprot id: Q6BM14
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Interacts (via WxxxF/Y and LVxEF motifs) with PEX14; promoting translocation through the PEX13-PEX14 docking complex.
messages: Monoubiquitinated at Cys-10 by PEX2 during PEX5 passage through the retrotranslocation channel: monoubiquitination acts as a signal for PEX5 extraction and is required for proper export from peroxisomes and recycling. When PEX5 recycling is compromised, polyubiquitinated at Lys-22 by PEX10 during its passage through the retrotranslocation channel, leading to its degradation.
messages: Peroxisome matrix
messages: Receptor that mediates peroxisomal import of proteins containing a C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type). Binds to cargo proteins containing a PTS1 peroxisomal targeting signal in the cytosol, and translocates them into the peroxisome matrix by passing through the PEX13-PEX14 docking complex along with cargo proteins. PEX5 receptor is then retrotranslocated into the cytosol, leading to release of bound cargo in the peroxisome matrix, and reset for a subsequent peroxisome import cycle.
messages: The TPR repeats mediate interaction with proteins containing a C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type).
messages: The WxxxF/Y motifs mediate interaction with PEX14, promoting association with the PEX13-PEX14 docking complex.
messages: The amphipathic helix 1 and 2 (AH1 and AH2, respectively) are required for PEX5 retrotranslocation and recycling. AH2 mediates interaction with lumenal side of the PEX2-PEX10-PEX12 ligase complex, while AH1 is required for extraction from peroxisomal membrane by the PEX1-PEX6 AAA ATPase complex.
messages: cytosol

284592:DEHA2F07260g
gene id: 284592:DEHA2F07260g
uniprot id: Q6BM97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2G23232g
gene id: 284592:DEHA2G23232g
uniprot id: B5RUZ7
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

284592:DEHA2C02112g
gene id: 284592:DEHA2C02112g
uniprot id: Q6BVJ7
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

284592:DEHA2C07744g
gene id: 284592:DEHA2C07744g
uniprot id: Q6BUV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Nucleus

284592:DEHA2C03718g
gene id: 284592:DEHA2C03718g
uniprot id: Q6BVC6
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C01936g
gene id: 284592:DEHA2C01936g
uniprot id: Q6BVK4
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2C15048g
gene id: 284592:DEHA2C15048g
uniprot id: Q6BTY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWC3 family.
messages: Nucleus

284592:DEHA2F15356g
gene id: 284592:DEHA2F15356g
uniprot id: Q6BL93
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

284592:DEHA2G24970g
gene id: 284592:DEHA2G24970g
uniprot id: Q6BGP1
names: Subcellular Location Annotation
messages: cell wall

284592:DEHA2D10230g
gene id: 284592:DEHA2D10230g
uniprot id: Q6BSB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INP1 family.
messages: Membrane
messages: Peroxisome membrane
messages: Required for peroxisome inheritance.

284592:DEHA2G15686g
gene id: 284592:DEHA2G15686g
uniprot id: Q6BHU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPS2 family.
messages: Cell membrane
messages: Membrane

284592:DEHA2C13486g
gene id: 284592:DEHA2C13486g
uniprot id: Q6BU54
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in translation initiation. Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes (By similarity).
messages: Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
messages: Cytoplasm
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284592:DEHA2G18194g
gene id: 284592:DEHA2G18194g
uniprot id: Q6BHJ0
names: Similarity
messages: Belongs to the RNase PH family.

284592:DEHA2A03256g
gene id: 284592:DEHA2A03256g
uniprot id: Q6BZ84
names: Similarity
messages: Belongs to the peptidase A1 family.

284592:DEHA2C17424g
gene id: 284592:DEHA2C17424g
uniprot id: Q6BTM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2G02398g
gene id: 284592:DEHA2G02398g
uniprot id: Q6BJH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Mitochondrion inner membrane

284592:DEHA2G23100g
gene id: 284592:DEHA2G23100g
uniprot id: B5RUZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2F14850g
gene id: 284592:DEHA2F14850g
uniprot id: Q6BLB5
names: Similarity
messages: Belongs to the NXF family.

284592:DEHA2A02464g
gene id: 284592:DEHA2A02464g
uniprot id: Q6BZC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. RKM1 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase.

284592:DEHA2G13244g
gene id: 284592:DEHA2G13244g
uniprot id: Q6BI58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Endoplasmic reticulum membrane
messages: Functions as a zinc transporter.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

284592:DEHA2F13552g
gene id: 284592:DEHA2F13552g
uniprot id: Q6BLG8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIS1 family.
messages: Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation (By similarity).
messages: Mitochondrion outer membrane
messages: The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.

284592:DEHA2A12342g
gene id: 284592:DEHA2A12342g
uniprot id: Q6BY52
names: Function
names: Similarity
messages: Belongs to the dihydroxyacetone kinase (DAK) family.
messages: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.

284592:DEHA2C09020g
gene id: 284592:DEHA2C09020g
uniprot id: Q6BUQ0
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E08250g
gene id: 284592:DEHA2E08250g
uniprot id: Q6BQ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

284592:DEHA2D01188g
gene id: 284592:DEHA2D01188g
uniprot id: Q6BTF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

284592:DEHA2F06512g
gene id: 284592:DEHA2F06512g
uniprot id: Q6BMD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ALG14 family.
messages: Endoplasmic reticulum membrane
messages: Heterodimer with ALG13 to form a functional enzyme.
messages: Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit ALG13 to the ER (By similarity).
messages: Nucleus membrane

284592:DEHA2C11528g
gene id: 284592:DEHA2C11528g
uniprot id: Q6BUE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

284592:DEHA2B11572g
gene id: 284592:DEHA2B11572g
uniprot id: Q6BWG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in cytoplasmic tRNA.

284592:DEHA2B03542g
gene id: 284592:DEHA2B03542g
uniprot id: Q6BXF1
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G15972g
gene id: 284592:DEHA2G15972g
uniprot id: Q6BHT4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autopalmitoylated.
messages: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
messages: Endoplasmic reticulum membrane
messages: Interacts with ERF4.
messages: The DHHC domain is required for palmitoyltransferase activity.
messages: The ERF2-ERF4 complex is a palmitoyltransferase specific for Ras proteins.

284592:DEHA2F05874g
gene id: 284592:DEHA2F05874g
uniprot id: B5RUA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2C08580g
gene id: 284592:DEHA2C08580g
uniprot id: Q6BUR8
names: Similarity
messages: Belongs to the histidine acid phosphatase family.

284592:DEHA2G19140g
gene id: 284592:DEHA2G19140g
uniprot id: Q6B4U7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Homooctamer.

284592:DEHA2E10626g
gene id: 284592:DEHA2E10626g
uniprot id: Q6BPV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fungal cytochrome c oxidase subunit 7a family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

284592:DEHA2G06116g
gene id: 284592:DEHA2G06116g
uniprot id: Q6BJ08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with missfolded ER lumenal proteins.
messages: Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation (By similarity).

284592:DEHA2B13948g
gene id: 284592:DEHA2B13948g
uniprot id: Q6BW66
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

284592:DEHA2F08140g
gene id: 284592:DEHA2F08140g
uniprot id: Q6BM57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

284592:DEHA2C16918g
gene id: 284592:DEHA2C16918g
uniprot id: Q6BTP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

284592:DEHA2A06644g
gene id: 284592:DEHA2A06644g
uniprot id: Q6BYV7
names: Function
names: Similarity
messages: Belongs to the IRC19 family.
messages: Involved in sporulation and maintenance of the mitochondrial DNA. Is probably involved in a pathway contributing to genomic integrity.

284592:DEHA2C04356g
gene id: 284592:DEHA2C04356g
uniprot id: Q6BV95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

284592:DEHA2F18986g
gene id: 284592:DEHA2F18986g
uniprot id: Q6BKV1
names: Similarity
messages: Belongs to the threonine synthase family.

284592:DEHA2D12936g
gene id: 284592:DEHA2D12936g
uniprot id: Q6BRY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
messages: Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2-methylisocitrate.
messages: Glyoxysome
messages: Homotetramer.

284592:DEHA2E22220g
gene id: 284592:DEHA2E22220g
uniprot id: Q6BNF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Cytoplasm
messages: MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle. Phosphorylates histone H2B to form H2BS10ph (By similarity).
messages: Nucleus

284592:DEHA2D13530g
gene id: 284592:DEHA2D13530g
uniprot id: Q6BRV5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Cytoplasm
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PAB1 (via PABC domain), conferring substrate specificity of the enzyme complex.
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

284592:DEHA2F06578g
gene id: 284592:DEHA2F06578g
uniprot id: Q6BMC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC2 family.
messages: Nucleus

284592:DEHA2F01804g
gene id: 284592:DEHA2F01804g
uniprot id: Q6BMX8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

284592:DEHA2D06908g
gene id: 284592:DEHA2D06908g
uniprot id: Q6BSQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2C05632g
gene id: 284592:DEHA2C05632g
uniprot id: Q6BV38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

284592:DEHA2E01628g
gene id: 284592:DEHA2E01628g
uniprot id: Q6BQX0
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

284592:DEHA2D12980g
gene id: 284592:DEHA2D12980g
uniprot id: Q6BRY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
messages: Interacts with a number of cyclins.
messages: When phosphate concentrations are high it phosphorylates the PHO4 transcription factor thus establishing repression.

284592:DEHA2G02002g
gene id: 284592:DEHA2G02002g
uniprot id: Q6BJJ3
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

284592:DEHA2F04422g
gene id: 284592:DEHA2F04422g
uniprot id: Q6BML3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RMD9 family.
messages: Binds the 3'-UTR of mitochondrial mRNAs. Involved in the processing or stability of mitochondrial mRNAs.
messages: Mitochondrion inner membrane
messages: Monomer.
messages: Phosphorylated. Phosphorylation promotes binding to RNA.

284592:DEHA2D01650g
gene id: 284592:DEHA2D01650g
uniprot id: Q6BTD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

284592:DEHA2B03322g
gene id: 284592:DEHA2B03322g
uniprot id: Q6BXG0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase required for ribosome biogenesis. Involved in the release of U14 snoRNA in pre-ribosomal complexes. Required for pre-rRNA cleavage at site A2 (By similarity).
messages: Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily.
messages: Interacts with the U3 and U14 snoRNAs. Associates with pre-ribosomal complexes (By similarity).
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284592:DEHA2F18304g
gene id: 284592:DEHA2F18304g
uniprot id: Q6BKW7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated by GCN5 to form H2BK11ac and H2BK16ac. H2BK16ac can also be formed by ESA1. Acetylation of N-terminal lysines and particularly formation of H2BK11acK16ac has a positive effect on transcription (By similarity).
messages: Belongs to the histone H2B family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Monoubiquitinated by the UBC2-BRE1 complex to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for H3K4me and H3K79me formation. H2BK123ub1 also modulates the formation of double-strand breaks during meiosis and is a prerequisite for DNA-damage checkpoint activation (By similarity).
messages: Nucleus
messages: Phosphorylated by STE20 to form H2BS10ph during progression through meiotic prophase. May be correlated with chromosome condensation (By similarity).
messages: Sumoylation to form H2BK6su or H2BK7su, and probably also H2BK16su or H2BK17su, occurs preferentially near the telomeres and represses gene transcription.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H2BK6ac = acetylated Lys-7; H2BK6su = sumoylated Lys-7; H2BK7ac = acetylated Lys-8; H2BK7su = sumoylated Lys-8; H2BS10ph = phosphorylated Ser-11; H2BK11ac = acetylated Lys-12; H2BK16ac = acetylated Lys-17; H2BK16su = sumoylated Lys-17; H2BK17su = sumoylated Lys-18; H2BK123ub1 = monoubiquitinated Lys-123.

284592:DEHA2F17864g
gene id: 284592:DEHA2F17864g
uniprot id: Q6BKY4
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

284592:DEHA2D07480g
gene id: 284592:DEHA2D07480g
uniprot id: B5RTF1
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D11572g
gene id: 284592:DEHA2D11572g
uniprot id: Q6BS50
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F05038g
gene id: 284592:DEHA2F05038g
uniprot id: B5RU99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSM3 family.
messages: Component of the fork protection complex (FPC) consisting of TOF1 and CSM3.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

284592:DEHA2A04378g
gene id: 284592:DEHA2A04378g
uniprot id: Q6BZ57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose (By similarity).

284592:DEHA2E14630g
gene id: 284592:DEHA2E14630g
uniprot id: B5RU15
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G05412g
gene id: 284592:DEHA2G05412g
uniprot id: Q6BJ40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

284592:DEHA2B12936g
gene id: 284592:DEHA2B12936g
uniprot id: Q6BWB2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

284592:DEHA2D13046g
gene id: 284592:DEHA2D13046g
uniprot id: Q6BRX9
names: Similarity
messages: Belongs to the SKP1 family.

284592:DEHA2F15928g
gene id: 284592:DEHA2F15928g
uniprot id: Q6BL69
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

284592:DEHA2A13728g
gene id: 284592:DEHA2A13728g
uniprot id: Q6BXZ3
names: Similarity
messages: Belongs to the PIH1 family.

284592:DEHA2F20152g
gene id: 284592:DEHA2F20152g
uniprot id: Q6BKP9
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

284592:DEHA2F10582g
gene id: 284592:DEHA2F10582g
uniprot id: Q6BLU7
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

284592:DEHA2G03058g
gene id: 284592:DEHA2G03058g
uniprot id: Q6BJE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

284592:DEHA2G07370g
gene id: 284592:DEHA2G07370g
uniprot id: Q6BIV3
names: Similarity
messages: Belongs to the CIA30 family.

284592:DEHA2C08998g
gene id: 284592:DEHA2C08998g
uniprot id: Q6BUQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 12 family.
messages: Component of the SRB8-11 complex, which itself associates with the Mediator complex.
messages: Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
messages: Nucleus

284592:DEHA2E20966g
gene id: 284592:DEHA2E20966g
uniprot id: Q6BNK6
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

284592:DEHA2F03872g
gene id: 284592:DEHA2F03872g
uniprot id: Q6BMN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Expected to bind 2 Fe(2+) ions per subunit.
messages: Membrane
messages: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.

284592:DEHA2E08338g
gene id: 284592:DEHA2E08338g
uniprot id: Q6BQ50
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

284592:DEHA2F23760g
gene id: 284592:DEHA2F23760g
uniprot id: Q6BK95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

284592:DEHA2D05808g
gene id: 284592:DEHA2D05808g
uniprot id: Q6BSV1
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F05962g
gene id: 284592:DEHA2F05962g
uniprot id: Q6BMF2
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

284592:DEHA2B01276g
gene id: 284592:DEHA2B01276g
uniprot id: Q6BXP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane

284592:DEHA2E11396g
gene id: 284592:DEHA2E11396g
uniprot id: Q6BPR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the palH/RIM21 family.
messages: Cell membrane
messages: Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.

284592:DEHA2A06908g
gene id: 284592:DEHA2A06908g
uniprot id: Q6BYU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

284592:DEHA2F09680g
gene id: 284592:DEHA2F09680g
uniprot id: Q6BLY9
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

284592:DEHA2D16412g
gene id: 284592:DEHA2D16412g
uniprot id: Q6BRH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAD2 family.
messages: Nucleus

284592:DEHA2C03652g
gene id: 284592:DEHA2C03652g
uniprot id: Q6BVC9
names: Similarity
messages: Belongs to the SELO family.

284592:DEHA2G04334g
gene id: 284592:DEHA2G04334g
uniprot id: Q6BJ87
names: Similarity
messages: Belongs to the UPF0507 family.

284592:DEHA2D17996g
gene id: 284592:DEHA2D17996g
uniprot id: B5RTK8
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

284592:DEHA2D07172g
gene id: 284592:DEHA2D07172g
uniprot id: Q6BSP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the crooked-neck family.
messages: Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication (By similarity).
messages: Nucleus

284592:DEHA2F26774g
gene id: 284592:DEHA2F26774g
uniprot id: Q6BJW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERT1/acuK family.
messages: Nucleus
messages: Transcription factor which regulates nonfermentable carbon utilization.

284592:DEHA2G11088g
gene id: 284592:DEHA2G11088g
uniprot id: Q6BIE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

284592:DEHA2D04972g
gene id: 284592:DEHA2D04972g
uniprot id: Q6BSY8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.

284592:DEHA2B15532g
gene id: 284592:DEHA2B15532g
uniprot id: Q6BVZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2F00154g
gene id: 284592:DEHA2F00154g
uniprot id: Q6BN52
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D18876g
gene id: 284592:DEHA2D18876g
uniprot id: B5RTM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2A12276g
gene id: 284592:DEHA2A12276g
uniprot id: Q6BY55
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2E12254g
gene id: 284592:DEHA2E12254g
uniprot id: Q6BPN1
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.

284592:DEHA2E18282g
gene id: 284592:DEHA2E18282g
uniprot id: Q6BNX5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

284592:DEHA2F09636g
gene id: 284592:DEHA2F09636g
uniprot id: Q6BLZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YSP2 family.
messages: Membrane

284592:DEHA2E16060g
gene id: 284592:DEHA2E16060g
uniprot id: Q6BP69
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2G08866g
gene id: 284592:DEHA2G08866g
uniprot id: Q6BIN9
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

284592:DEHA2G18722g
gene id: 284592:DEHA2G18722g
uniprot id: Q6BHG7
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2G15862g
gene id: 284592:DEHA2G15862g
uniprot id: Q6BHT9
names: Function
names: Similarity
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.

284592:DEHA2F09460g
gene id: 284592:DEHA2F09460g
uniprot id: Q6BLZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

284592:DEHA2G01826g
gene id: 284592:DEHA2G01826g
uniprot id: Q6BJK1
names: Subcellular Location Annotation
messages: nucleolus

284592:DEHA2E15202g
gene id: 284592:DEHA2E15202g
uniprot id: Q6BPA4
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

284592:DEHA2F18106g
gene id: 284592:DEHA2F18106g
uniprot id: Q6BKX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM24 family.
messages: Mitochondrion

284592:DEHA2G15444g
gene id: 284592:DEHA2G15444g
uniprot id: Q6BHV7
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

284592:DEHA2G17270g
gene id: 284592:DEHA2G17270g
uniprot id: Q6BHN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

284592:DEHA2F23892g
gene id: 284592:DEHA2F23892g
uniprot id: Q6BK90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 2 family.
messages: Nucleus

284592:DEHA2F18744g
gene id: 284592:DEHA2F18744g
uniprot id: Q6BKW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Cytoplasm
messages: Presumably involved in regulating the intracellular acetyl-CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.

284592:DEHA2F25168g
gene id: 284592:DEHA2F25168g
uniprot id: Q6BK37
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2F22616g
gene id: 284592:DEHA2F22616g
uniprot id: Q6BKE5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2F00374g
gene id: 284592:DEHA2F00374g
uniprot id: Q6BN43
names: Similarity
messages: Belongs to the MSOX/MTOX family.

284592:DEHA2C02596g
gene id: 284592:DEHA2C02596g
uniprot id: Q6BVH7
names: Similarity
messages: Belongs to the cytochrome P450 family.

284592:DEHA2C07326g
gene id: 284592:DEHA2C07326g
uniprot id: Q6BUW8
names: Function
names: Similarity
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.

284592:DEHA2A08580g
gene id: 284592:DEHA2A08580g
uniprot id: Q6BYL8
names: Similarity
messages: Belongs to the actin family.

284592:DEHA2D09372g
gene id: 284592:DEHA2D09372g
uniprot id: Q6BSE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2F21318g
gene id: 284592:DEHA2F21318g
uniprot id: B5RUK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: Endoplasmic reticulum membrane
messages: May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.
messages: Membrane

284592:DEHA2A05060g
gene id: 284592:DEHA2A05060g
uniprot id: Q6BZ28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCM1 family.
messages: Mitochondrion
messages: RNA-binding protein involved in the specific removal of group I introns in mitochondrial encoded transcripts. Maintains the stability of the small subunit mitochondrial 15S rRNA and thus the expression of the mitochondrial genome (By similarity).

284592:DEHA2B02574g
gene id: 284592:DEHA2B02574g
uniprot id: Q6BXI9
names: Similarity
messages: Belongs to the exportin family.

284592:DEHA2E12144g
gene id: 284592:DEHA2E12144g
uniprot id: Q6BPN6
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

284592:DEHA2E13486g
gene id: 284592:DEHA2E13486g
uniprot id: Q6BPH9
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

284592:DEHA2A02156g
gene id: 284592:DEHA2A02156g
uniprot id: Q6BZD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: nuclear pore complex

284592:DEHA2D15510g
gene id: 284592:DEHA2D15510g
uniprot id: Q6BRL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRO1 family.
messages: Cytoplasm
messages: Endosome
messages: Involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles.

284592:DEHA2G21978g
gene id: 284592:DEHA2G21978g
uniprot id: Q6BH22
names: Domain
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DENR family.
messages: Cytoplasm
messages: Interacts with the 40S ribosomal subunit.
messages: The SUI1 domain may be involved in RNA binding.

284592:DEHA2F10010g
gene id: 284592:DEHA2F10010g
uniprot id: Q6BLX1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.

284592:DEHA2E15598g
gene id: 284592:DEHA2E15598g
uniprot id: Q6BP87
names: Similarity
messages: Belongs to the PP2C family.

284592:DEHA2B15686g
gene id: 284592:DEHA2B15686g
uniprot id: B5RSW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

284592:DEHA2F04554g
gene id: 284592:DEHA2F04554g
uniprot id: Q6BMK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284592:DEHA2E23914g
gene id: 284592:DEHA2E23914g
uniprot id: Q6BN80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diphthine synthase family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

284592:DEHA2G03278g
gene id: 284592:DEHA2G03278g
uniprot id: Q6BJD3
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E10912g
gene id: 284592:DEHA2E10912g
uniprot id: Q6BPT8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Associated with pre-ribosomal particles.
messages: Belongs to the DEAD box helicase family. DDX51/DBP6 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284592:DEHA2B01804g
gene id: 284592:DEHA2B01804g
uniprot id: Q6BXM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Cytoplasm

284592:DEHA2B08646g
gene id: 284592:DEHA2B08646g
uniprot id: Q6BWT7
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F23012g
gene id: 284592:DEHA2F23012g
uniprot id: Q6BKC8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.

284592:DEHA2D11044g
gene id: 284592:DEHA2D11044g
uniprot id: Q6BS75
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

284592:DEHA2F23584g
gene id: 284592:DEHA2F23584g
uniprot id: Q6BKA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Homododecamer. Adopts a ring-like structure, composed of an arrangement of two hexameric rings stacked on top of one another.
messages: Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway.

284592:DEHA2F14828g
gene id: 284592:DEHA2F14828g
uniprot id: Q6BLB6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family.
messages: Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

284592:DEHA2E06776g
gene id: 284592:DEHA2E06776g
uniprot id: Q6BQB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family.
messages: Cell membrane
messages: Vacuole membrane

284592:DEHA2D15818g
gene id: 284592:DEHA2D15818g
uniprot id: Q6BRJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPL4 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity).
messages: Nucleus membrane
messages: perinuclear region

284592:DEHA2A06820g
gene id: 284592:DEHA2A06820g
uniprot id: Q6BYU8
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

284592:DEHA2A00264g
gene id: 284592:DEHA2A00264g
uniprot id: Q6BZM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

284592:DEHA2F04136g
gene id: 284592:DEHA2F04136g
uniprot id: Q6BMM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover (By similarity). Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA (By similarity).
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2G19844g
gene id: 284592:DEHA2G19844g
uniprot id: Q6BHB5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

284592:DEHA2F05610g
gene id: 284592:DEHA2F05610g
uniprot id: Q6BMG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Component of the checkpoint clamp complex involved in the surveillance mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes.
messages: Nucleus

284592:DEHA2A07084g
gene id: 284592:DEHA2A07084g
uniprot id: Q6BYT6
names: Similarity
messages: Belongs to the R-transferase family.

284592:DEHA2B10978g
gene id: 284592:DEHA2B10978g
uniprot id: Q6BWI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

284592:DEHA2G05390g
gene id: 284592:DEHA2G05390g
uniprot id: Q6BJ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2E12430g
gene id: 284592:DEHA2E12430g
uniprot id: B5RTZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

284592:DEHA2A13618g
gene id: 284592:DEHA2A13618g
uniprot id: B5RSM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

284592:DEHA2B01452g
gene id: 284592:DEHA2B01452g
uniprot id: B5RT21
names: Subcellular Location Annotation
messages: cell wall

284592:DEHA2B01936g
gene id: 284592:DEHA2B01936g
uniprot id: Q6BXL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for proper protein synthesis within the mitochondrion.
messages: Belongs to the GatF family.
messages: Mitochondrion inner membrane
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.

284592:DEHA2E07590g
gene id: 284592:DEHA2E07590g
uniprot id: Q6BQ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

284592:DEHA2E07634g
gene id: 284592:DEHA2E07634g
uniprot id: Q6BQ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

284592:DEHA2D10714g
gene id: 284592:DEHA2D10714g
uniprot id: Q6BS91
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2B07392g
gene id: 284592:DEHA2B07392g
uniprot id: Q6BWY9
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

284592:DEHA2B10494g
gene id: 284592:DEHA2B10494g
uniprot id: Q6BWL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cut8/STS1 family.
messages: Binds the proteasome.
messages: Cytoplasm
messages: Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
messages: Nucleus

284592:DEHA2E05412g
gene id: 284592:DEHA2E05412g
uniprot id: Q6BQG6
names: Similarity
messages: Belongs to the RNase Z family.

284592:DEHA2C13684g
gene id: 284592:DEHA2C13684g
uniprot id: Q6BU46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

284592:DEHA2G05808g
gene id: 284592:DEHA2G05808g
uniprot id: Q6BJ23
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

284592:DEHA2D07128g
gene id: 284592:DEHA2D07128g
uniprot id: B5RTE4
names: Similarity
messages: Belongs to the peptidase M28 family.

284592:DEHA2C17204g
gene id: 284592:DEHA2C17204g
uniprot id: Q6BTN2
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

284592:DEHA2F18964g
gene id: 284592:DEHA2F18964g
uniprot id: Q6BKV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTR86 family.
messages: Cytoplasm
messages: Essential protein which may be involved in threonine biosynthesis.

284592:DEHA2F01738g
gene id: 284592:DEHA2F01738g
uniprot id: Q6BMY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

284592:DEHA2B03014g
gene id: 284592:DEHA2B03014g
uniprot id: Q6BXH3
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

284592:DEHA2F17358g
gene id: 284592:DEHA2F17358g
uniprot id: Q6BL05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

284592:DEHA2B00506g
gene id: 284592:DEHA2B00506g
uniprot id: Q6BXT0
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C04488g
gene id: 284592:DEHA2C04488g
uniprot id: Q6BV89
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

284592:DEHA2F02112g
gene id: 284592:DEHA2F02112g
uniprot id: Q6BMW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

284592:DEHA2B15268g
gene id: 284592:DEHA2B15268g
uniprot id: Q6BS28
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

284592:DEHA2F14542g
gene id: 284592:DEHA2F14542g
uniprot id: B5RUG8
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2B06732g
gene id: 284592:DEHA2B06732g
uniprot id: Q6BX18
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

284592:DEHA2G09328g
gene id: 284592:DEHA2G09328g
uniprot id: B5RV58
names: Similarity
messages: Belongs to the peptidase C19 family.

284592:DEHA2G10604g
gene id: 284592:DEHA2G10604g
uniprot id: Q6BIG7
names: Similarity
messages: Belongs to the TCP11 family.

284592:DEHA2G19294g
gene id: 284592:DEHA2G19294g
uniprot id: Q6BHE3
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G11726g
gene id: 284592:DEHA2G11726g
uniprot id: B5RUR2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

284592:DEHA2A08140g
gene id: 284592:DEHA2A08140g
uniprot id: Q6BYN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2A03322g
gene id: 284592:DEHA2A03322g
uniprot id: Q6BZ81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

284592:DEHA2D09504g
gene id: 284592:DEHA2D09504g
uniprot id: Q6BSE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication in an ATP-dependent manner (By similarity).
messages: Nucleus
messages: ORC is composed of six subunits.

284592:DEHA2G00704g
gene id: 284592:DEHA2G00704g
uniprot id: Q6BJQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for the ferulic acid decarboxylase FDC1. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Mitochondrion
messages: Oligomer.

284592:DEHA2A12760g
gene id: 284592:DEHA2A12760g
uniprot id: Q6BY36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2G13948g
gene id: 284592:DEHA2G13948g
uniprot id: B5RUS7
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

284592:DEHA2F25586g
gene id: 284592:DEHA2F25586g
uniprot id: Q6BK19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.
messages: coated pit

284592:DEHA2G14410g
gene id: 284592:DEHA2G14410g
uniprot id: Q6BI07
names: Similarity
messages: Belongs to the UTP6 family.

284592:DEHA2D06556g
gene id: 284592:DEHA2D06556g
uniprot id: Q6BSS7
names: Similarity
messages: Belongs to the dopey family.

284592:DEHA2F16742g
gene id: 284592:DEHA2F16742g
uniprot id: Q6BL33
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

284592:DEHA2E20504g
gene id: 284592:DEHA2E20504g
uniprot id: Q6BNM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

284592:DEHA2A12980g
gene id: 284592:DEHA2A12980g
uniprot id: Q6BY26
names: Similarity
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.

284592:DEHA2A12518g
gene id: 284592:DEHA2A12518g
uniprot id: Q6BY45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

284592:DEHA2C12584g
gene id: 284592:DEHA2C12584g
uniprot id: Q6BU97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).

284592:DEHA2F23518g
gene id: 284592:DEHA2F23518g
uniprot id: Q6BKA6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2C07282g
gene id: 284592:DEHA2C07282g
uniprot id: Q6BUX0
names: Similarity
messages: Belongs to the aspartokinase family.

284592:DEHA2A04994g
gene id: 284592:DEHA2A04994g
uniprot id: Q6BZ31
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284592:DEHA2F19426g
gene id: 284592:DEHA2F19426g
uniprot id: Q6BKT2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284592:DEHA2C08338g
gene id: 284592:DEHA2C08338g
uniprot id: Q6BUS9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM34 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
messages: Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.
messages: Mitochondrion outer membrane
messages: The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.

284592:DEHA2E03674g
gene id: 284592:DEHA2E03674g
uniprot id: Q6BQN6
names: Similarity
messages: Belongs to the PPP phosphatase family.

284592:DEHA2G21010g
gene id: 284592:DEHA2G21010g
uniprot id: Q6BH65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family. PIGB subfamily.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly (By similarity).

284592:DEHA2D12870g
gene id: 284592:DEHA2D12870g
uniprot id: Q6BRY7
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G15928g
gene id: 284592:DEHA2G15928g
uniprot id: Q6BHT6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CybS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2C06292g
gene id: 284592:DEHA2C06292g
uniprot id: Q6BV08
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D14036g
gene id: 284592:DEHA2D14036g
uniprot id: Q6BRT2
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

284592:DEHA2G10428g
gene id: 284592:DEHA2G10428g
uniprot id: Q6BIH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVF1 family.
messages: Cytoplasm
messages: May be involved in the response to oxidative stress.
messages: Nucleus

284592:DEHA2B00792g
gene id: 284592:DEHA2B00792g
uniprot id: Q6BXR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

284592:DEHA2A02706g
gene id: 284592:DEHA2A02706g
uniprot id: Q6BZB2
names: Similarity
messages: Belongs to the oxoprolinase family.

284592:DEHA2F04840g
gene id: 284592:DEHA2F04840g
uniprot id: Q6BMJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

284592:DEHA2A14806g
gene id: 284592:DEHA2A14806g
uniprot id: Q6BXU9
names: Similarity
messages: Belongs to the tannase family.

284592:DEHA2C06864g
gene id: 284592:DEHA2C06864g
uniprot id: Q6BUY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

284592:DEHA2F08382g
gene id: 284592:DEHA2F08382g
uniprot id: Q6BM46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

284592:DEHA2G12276g
gene id: 284592:DEHA2G12276g
uniprot id: Q6BIA5
names: Similarity
messages: Belongs to the DeSI family.

284592:DEHA2C00506g
gene id: 284592:DEHA2C00506g
uniprot id: Q6BVR7
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G03674g
gene id: 284592:DEHA2G03674g
uniprot id: Q6BJB6
names: Similarity
messages: Belongs to the SEC6 family.

284592:DEHA2B08052g
gene id: 284592:DEHA2B08052g
uniprot id: Q6BWW3
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2C17930g
gene id: 284592:DEHA2C17930g
uniprot id: B5RTD9
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E15840g
gene id: 284592:DEHA2E15840g
uniprot id: B5RU22
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

284592:DEHA2A14058g
gene id: 284592:DEHA2A14058g
uniprot id: Q6BXX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

284592:DEHA2G14586g
gene id: 284592:DEHA2G14586g
uniprot id: B5RUS9
names: Similarity
messages: Belongs to the peptidase M18 family.

284592:DEHA2C08294g
gene id: 284592:DEHA2C08294g
uniprot id: W0TYR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

284592:DEHA2E05060g
gene id: 284592:DEHA2E05060g
uniprot id: Q6BQI0
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

284592:DEHA2C10274g
gene id: 284592:DEHA2C10274g
uniprot id: Q6BUJ0
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.

284592:DEHA2A02882g
gene id: 284592:DEHA2A02882g
uniprot id: B5RSP7
names: Subcellular Location Annotation
messages: nucleolus

284592:DEHA2F01254g
gene id: 284592:DEHA2F01254g
uniprot id: Q6BN03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

284592:DEHA2B06886g
gene id: 284592:DEHA2B06886g
uniprot id: Q6BX11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Mitochondrion inner membrane

284592:DEHA2E01826g
gene id: 284592:DEHA2E01826g
uniprot id: Q6BQW0
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2G07216g
gene id: 284592:DEHA2G07216g
uniprot id: Q6BIV9
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2A07414g
gene id: 284592:DEHA2A07414g
uniprot id: Q6BYS1
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

284592:DEHA2B10296g
gene id: 284592:DEHA2B10296g
uniprot id: Q6BWL9
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

284592:DEHA2F00418g
gene id: 284592:DEHA2F00418g
uniprot id: Q6BN41
names: Subcellular Location Annotation
messages: cell wall

284592:DEHA2G14102g
gene id: 284592:DEHA2G14102g
uniprot id: Q6BI18
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

284592:DEHA2E11264g
gene id: 284592:DEHA2E11264g
uniprot id: Q6BPS2
names: Similarity
messages: Belongs to the OSBP family.

284592:DEHA2G13926g
gene id: 284592:DEHA2G13926g
uniprot id: Q6BI26
names: Similarity
messages: Belongs to the WD repeat mio family.

284592:DEHA2G04730g
gene id: 284592:DEHA2G04730g
uniprot id: Q6BJ70
names: Similarity
messages: Belongs to the syntaxin family.

284592:DEHA2G19272g
gene id: 284592:DEHA2G19272g
uniprot id: Q6BHE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2F23496g
gene id: 284592:DEHA2F23496g
uniprot id: B5RUM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

284592:DEHA2D10208g
gene id: 284592:DEHA2D10208g
uniprot id: Q6BSB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

284592:DEHA2F10208g
gene id: 284592:DEHA2F10208g
uniprot id: Q6BLW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku70 family.
messages: Nucleus
messages: telomere

284592:DEHA2B01254g
gene id: 284592:DEHA2B01254g
uniprot id: Q6BXP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IML2 family.
messages: Cytoplasm
messages: Inclusion body (IB) resident protein that interacts strongly with lipid droplet (LD) proteins. Involved in LD-mediated IB clearing after protein folding stress, probably by enabling access to the IBs of an LD-stored soluble sterol derivative that acts as chaperone in inclusion clearing.
messages: Interacts with lipid droplet proteins.
messages: Nucleus

284592:DEHA2B01892g
gene id: 284592:DEHA2B01892g
uniprot id: Q6BXM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

284592:DEHA2C00220g
gene id: 284592:DEHA2C00220g
uniprot id: B5RT51
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E12738g
gene id: 284592:DEHA2E12738g
uniprot id: Q6BPL0
names: Similarity
messages: Belongs to the multicopper oxidase family.

284592:DEHA2D13464g
gene id: 284592:DEHA2D13464g
uniprot id: Q6BRV8
names: Function
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

284592:DEHA2G22704g
gene id: 284592:DEHA2G22704g
uniprot id: Q6BGY7
names: Similarity
messages: Belongs to the TMEM14 family.

284592:DEHA2G10318g
gene id: 284592:DEHA2G10318g
uniprot id: Q6BIH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284592:DEHA2F01100g
gene id: 284592:DEHA2F01100g
uniprot id: Q6BN10
names: Similarity
messages: Belongs to the FBPase class 1 family.

284592:DEHA2B10692g
gene id: 284592:DEHA2B10692g
uniprot id: Q6BWK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284592:DEHA2C16478g
gene id: 284592:DEHA2C16478g
uniprot id: Q6BTR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

284592:DEHA2E21010g
gene id: 284592:DEHA2E21010g
uniprot id: Q6BNK3
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2B06358g
gene id: 284592:DEHA2B06358g
uniprot id: B5RSY7
names: Similarity
messages: Belongs to the actin family.

284592:DEHA2F08932g
gene id: 284592:DEHA2F08932g
uniprot id: Q6BM21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

284592:DEHA2D10054g
gene id: 284592:DEHA2D10054g
uniprot id: Q6BSB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
messages: May form heterododecamers with RVB1. Component of the SWR1 chromatin remodeling complex, the INO80 chromatin remodeling complex, and of the R2TP complex (By similarity).
messages: Nucleus

284592:DEHA2G24574g
gene id: 284592:DEHA2G24574g
uniprot id: Q6BGR1
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

284592:DEHA2E22506g
gene id: 284592:DEHA2E22506g
uniprot id: Q6BNE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC25 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284592:DEHA2F11396g
gene id: 284592:DEHA2F11396g
uniprot id: Q6BLR1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284592:DEHA2E04202g
gene id: 284592:DEHA2E04202g
uniprot id: Q6BQL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2E18964g
gene id: 284592:DEHA2E18964g
uniprot id: Q6BNU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTAG/PCC1 family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. PCC1 functions as a dimerization module for the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators (By similarity).
messages: Nucleus
messages: telomere

284592:DEHA2F12980g
gene id: 284592:DEHA2F12980g
uniprot id: Q6BLJ3
names: Similarity
messages: Belongs to the NDK family.

284592:DEHA2B03058g
gene id: 284592:DEHA2B03058g
uniprot id: Q6BXH1
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

284592:DEHA2C01320g
gene id: 284592:DEHA2C01320g
uniprot id: Q6BVN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0057 (PMP3) family.
messages: Cell membrane
messages: Plays a role in the regulation of membrane potential. Could mediate a proton leak (By similarity).

284592:DEHA2D13728g
gene id: 284592:DEHA2D13728g
uniprot id: Q6BRU6
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

284592:DEHA2G03498g
gene id: 284592:DEHA2G03498g
uniprot id: Q6BJC3
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

284592:DEHA2C11704g
gene id: 284592:DEHA2C11704g
uniprot id: Q6BUD5
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

284592:DEHA2E03586g
gene id: 284592:DEHA2E03586g
uniprot id: Q6BQP0
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

284592:DEHA2D02178g
gene id: 284592:DEHA2D02178g
uniprot id: Q6BTA8
names: Similarity
messages: Belongs to the rtf2 family.

284592:DEHA2B08228g
gene id: 284592:DEHA2B08228g
uniprot id: Q6BWV5
names: Similarity
messages: Belongs to the eIF2D family.

284592:DEHA2B06820g
gene id: 284592:DEHA2B06820g
uniprot id: Q6BX14
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: As accessory component of the DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication.
messages: Heterotetramer. Consists of four subunits: POL2, DPB2, DPB3 and DPB4 (By similarity).
messages: In eukaryotes there are five DNA polymerases: alpha, beta, gamma, delta, and epsilon which are responsible for different reactions of DNA synthesis.
messages: Nucleus

284592:DEHA2F05984g
gene id: 284592:DEHA2F05984g
uniprot id: Q6BMF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal Na(+)/H(+) exchanger family.
messages: Membrane

284592:DEHA2C13662g
gene id: 284592:DEHA2C13662g
uniprot id: Q6BU47
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

284592:DEHA2G17292g
gene id: 284592:DEHA2G17292g
uniprot id: Q6BHN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

284592:DEHA2G21296g
gene id: 284592:DEHA2G21296g
uniprot id: Q6BH53
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

284592:DEHA2E19228g
gene id: 284592:DEHA2E19228g
uniprot id: Q6BNS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.

284592:DEHA2G03256g
gene id: 284592:DEHA2G03256g
uniprot id: Q6BJD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC family.
messages: Cytoplasm
messages: mRNA-binding protein which stimulates mRNA decapping.

284592:DEHA2F13684g
gene id: 284592:DEHA2F13684g
uniprot id: Q6BLG3
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

284592:DEHA2E14520g
gene id: 284592:DEHA2E14520g
uniprot id: Q6BPD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrion

284592:DEHA2F02046g
gene id: 284592:DEHA2F02046g
uniprot id: Q6BMW7
names: Similarity
messages: Belongs to the ADIP family.

284592:DEHA2F20834g
gene id: 284592:DEHA2F20834g
uniprot id: Q6BKL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
messages: Chromosome
messages: Component of the COMPASS (Set1C) complex.
messages: Nucleus

284592:DEHA2D12320g
gene id: 284592:DEHA2D12320g
uniprot id: Q6BS14
names: Similarity
messages: In the C-terminal section; belongs to the TrpB family.
messages: In the N-terminal section; belongs to the TrpA family.

284592:DEHA2C13046g
gene id: 284592:DEHA2C13046g
uniprot id: Q6BU76
names: Function
messages: Most effectively accelerate the intrinsic GTPase activity of YPT7. It is also active, but to a lesser extent, on YPT31, YPT32 and YPT1. YPT6 and SEC4 (By similarity).

284592:DEHA2C12100g
gene id: 284592:DEHA2C12100g
uniprot id: Q6BUB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC3 family.
messages: Nucleus

284592:DEHA2D10186g
gene id: 284592:DEHA2D10186g
uniprot id: Q6BSB2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Heterooctamer of 4 alpha and 4 beta chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284592:DEHA2A00594g
gene id: 284592:DEHA2A00594g
uniprot id: Q6BZK7
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

284592:DEHA2C08492g
gene id: 284592:DEHA2C08492g
uniprot id: Q6BUS2
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

284592:DEHA2E23760g
gene id: 284592:DEHA2E23760g
uniprot id: Q6BN87
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F10120g
gene id: 284592:DEHA2F10120g
uniprot id: Q6BLW6
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

284592:DEHA2E15466g
gene id: 284592:DEHA2E15466g
uniprot id: B5RU19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TEC1 family.
messages: Nucleus

284592:DEHA2E08998g
gene id: 284592:DEHA2E08998g
uniprot id: Q6BQ21
names: Similarity
messages: Belongs to the AFG1 ATPase family.

284592:DEHA2G16588g
gene id: 284592:DEHA2G16588g
uniprot id: Q6BHQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2B14784g
gene id: 284592:DEHA2B14784g
uniprot id: Q6BW29
names: Similarity
messages: Belongs to the threonine aldolase family.

284592:DEHA2D12034g
gene id: 284592:DEHA2D12034g
uniprot id: Q6BS28
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

284592:DEHA2C07238g
gene id: 284592:DEHA2C07238g
uniprot id: Q6BUX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Mitochondrion outer membrane
messages: Monomer. Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.
messages: NADH-dependent reductase for DPH3 and cytochrome b5. Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1. By reducing DPH3, also involved in the formation of the tRNA wobble base modification mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), mediated by the elongator complex. The cytochrome b5/NADH cytochrome b5 reductase electron transfer system supports the catalytic activity of several sterol biosynthetic enzymes.

284592:DEHA2B01474g
gene id: 284592:DEHA2B01474g
uniprot id: Q6BXN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLD2 family.
messages: Cytoplasm
messages: Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity).
messages: Nucleus

284592:DEHA2F14036g
gene id: 284592:DEHA2F14036g
uniprot id: Q6BLE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

284592:DEHA2G07656g
gene id: 284592:DEHA2G07656g
uniprot id: Q6BIU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

284592:DEHA2D00726g
gene id: 284592:DEHA2D00726g
uniprot id: Q6BTG9
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F05830g
gene id: 284592:DEHA2F05830g
uniprot id: Q6BMF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster facilitates the reduction of the catalytic iron-sulfur cluster in the DPH1 subunit.
messages: Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.
messages: Cytoplasm
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1 (By similarity). Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit (By similarity).

284592:DEHA2D01056g
gene id: 284592:DEHA2D01056g
uniprot id: Q6BTF5
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C13860g
gene id: 284592:DEHA2C13860g
uniprot id: Q6BU38
names: Similarity
messages: Belongs to the UFD1 family.

284592:DEHA2D18128g
gene id: 284592:DEHA2D18128g
uniprot id: Q6BR96
names: Similarity
messages: Belongs to the complex I LYR family. SDHAF1 subfamily.

284592:DEHA2G15312g
gene id: 284592:DEHA2G15312g
uniprot id: Q6BHW4
names: Similarity
messages: Belongs to the peptidase C12 family.

284592:DEHA2D15532g
gene id: 284592:DEHA2D15532g
uniprot id: Q6BRL2
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

284592:DEHA2F24112g
gene id: 284592:DEHA2F24112g
uniprot id: Q6BK81
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.

284592:DEHA2G04906g
gene id: 284592:DEHA2G04906g
uniprot id: Q6BJ62
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

284592:DEHA2A10780g
gene id: 284592:DEHA2A10780g
uniprot id: Q6BYB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

284592:DEHA2E16214g
gene id: 284592:DEHA2E16214g
uniprot id: Q6BP64
names: Similarity
messages: Belongs to the beclin family.

284592:DEHA2E24222g
gene id: 284592:DEHA2E24222g
uniprot id: B5RU69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

284592:DEHA2B13288g
gene id: 284592:DEHA2B13288g
uniprot id: Q6BW96
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.

284592:DEHA2D16610g
gene id: 284592:DEHA2D16610g
uniprot id: Q6BRG2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated by GCN5 to form H2BK11ac and H2BK16ac. H2BK16ac can also be formed by ESA1. Acetylation of N-terminal lysines and particularly formation of H2BK11acK16ac has a positive effect on transcription (By similarity).
messages: Belongs to the histone H2B family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Monoubiquitinated by the UBC2-BRE1 complex to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for H3K4me and H3K79me formation. H2BK123ub1 also modulates the formation of double-strand breaks during meiosis and is a prerequisite for DNA-damage checkpoint activation (By similarity).
messages: Nucleus
messages: Phosphorylated by STE20 to form H2BS10ph during progression through meiotic prophase. May be correlated with chromosome condensation (By similarity).
messages: Sumoylation to form H2BK6su or H2BK7su, and probably also H2BK16su or H2BK17su, occurs preferentially near the telomeres and represses gene transcription.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H2BK6ac = acetylated Lys-7; H2BK6su = sumoylated Lys-7; H2BK7ac = acetylated Lys-8; H2BK7su = sumoylated Lys-8; H2BS10ph = phosphorylated Ser-11; H2BK11ac = acetylated Lys-12; H2BK16ac = acetylated Lys-17; H2BK16su = sumoylated Lys-17; H2BK17su = sumoylated Lys-18; H2BK123ub1 = monoubiquitinated Lys-124.

284592:DEHA2F09526g
gene id: 284592:DEHA2F09526g
uniprot id: Q6BLZ6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

284592:DEHA2B06402g
gene id: 284592:DEHA2B06402g
uniprot id: Q6BX31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.
messages: Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.
messages: Cytoplasm
messages: P-body

284592:DEHA2D01584g
gene id: 284592:DEHA2D01584g
uniprot id: Q6BTD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

284592:DEHA2E10296g
gene id: 284592:DEHA2E10296g
uniprot id: Q6BPW8
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

284592:DEHA2E07128g
gene id: 284592:DEHA2E07128g
uniprot id: B5RTW6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

284592:DEHA2F26510g
gene id: 284592:DEHA2F26510g
uniprot id: Q6BJX9
names: Similarity
messages: Belongs to the XPO2/CSE1 family.

284592:DEHA2D08822g
gene id: 284592:DEHA2D08822g
uniprot id: Q6BSH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

284592:DEHA2E08206g
gene id: 284592:DEHA2E08206g
uniprot id: Q6BQ55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Cytoplasm

284592:DEHA2D18744g
gene id: 284592:DEHA2D18744g
uniprot id: Q6BR70
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

284592:DEHA2B14388g
gene id: 284592:DEHA2B14388g
uniprot id: Q6BW48
names: Similarity
messages: Belongs to the Rho GDI family.

284592:DEHA2E19272g
gene id: 284592:DEHA2E19272g
uniprot id: Q6BNS7
names: Similarity
messages: Belongs to the cytochrome P450 family.

284592:DEHA2C11638g
gene id: 284592:DEHA2C11638g
uniprot id: B5RTA0
names: Similarity
messages: Belongs to the cullin family.

284592:DEHA2A12232g
gene id: 284592:DEHA2A12232g
uniprot id: Q6BY57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Membrane

284592:DEHA2F25124g
gene id: 284592:DEHA2F25124g
uniprot id: Q6BK39
names: Similarity
messages: Belongs to the peptidase M24B family.

284592:DEHA2G21934g
gene id: 284592:DEHA2G21934g
uniprot id: Q6BH24
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2A06248g
gene id: 284592:DEHA2A06248g
uniprot id: Q6BYX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

284592:DEHA2F14652g
gene id: 284592:DEHA2F14652g
uniprot id: B5RUG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MON1/SAND family.
messages: Prevacuolar compartment membrane
messages: Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.
messages: Vacuole membrane
messages: multivesicular body membrane

284592:DEHA2D11330g
gene id: 284592:DEHA2D11330g
uniprot id: Q6BS62
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G24860g
gene id: 284592:DEHA2G24860g
uniprot id: Q6BGP8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

284592:DEHA2B04620g
gene id: 284592:DEHA2B04620g
uniprot id: Q6BXA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLA1 family.
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

284592:DEHA2G16566g
gene id: 284592:DEHA2G16566g
uniprot id: Q6BHR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

284592:DEHA2G10208g
gene id: 284592:DEHA2G10208g
uniprot id: Q6BII1
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

284592:DEHA2G01892g
gene id: 284592:DEHA2G01892g
uniprot id: Q6BJJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
messages: Belongs to the peptidase S16 family.
messages: Peroxisome matrix

284592:DEHA2A07986g
gene id: 284592:DEHA2A07986g
uniprot id: Q6BYP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RTT106 family.
messages: Chromosome
messages: Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity).
messages: Interacts with histones H3 and H4.
messages: Nucleus

284592:DEHA2E14806g
gene id: 284592:DEHA2E14806g
uniprot id: Q6BPC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

284592:DEHA2F07370g
gene id: 284592:DEHA2F07370g
uniprot id: Q6BM93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Fungal signal recognition particle consists of a 7S RNA molecule (scR1) and at least six protein subunits: SRP72, SRP68, SRP54, SEC65, SRP21 andSRP14.
messages: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. It must be involved intimately in the translocation of a wide variety of protein substrates (By similarity).

284592:DEHA2E12188g
gene id: 284592:DEHA2E12188g
uniprot id: Q6BPN4
names: Function
names: Similarity
messages: Belongs to the POA1 family.
messages: Highly specific phosphatase involved in the metabolism of ADP-ribose 1''-phosphate (Appr1p) which is produced as a consequence of tRNA splicing.

284592:DEHA2C10406g
gene id: 284592:DEHA2C10406g
uniprot id: Q6BUI4
names: Function
names: Similarity
messages: Belongs to the NARF family.
messages: Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).

284592:DEHA2G08954g
gene id: 284592:DEHA2G08954g
uniprot id: Q6BIN5
names: Similarity
messages: Belongs to the syntaxin family.

284592:DEHA2G23518g
gene id: 284592:DEHA2G23518g
uniprot id: Q6BGV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG7 family.
messages: Cytoplasm
messages: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Plays a role in the regulation of filamentous growth and chronological longevity (By similarity).
messages: Homodimer.
messages: Preautophagosomal structure
messages: The GxGxxG motif is important for the function, possibly through binding with ATP.

284592:DEHA2G24530g
gene id: 284592:DEHA2G24530g
uniprot id: Q6BGR3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

284592:DEHA2C04180g
gene id: 284592:DEHA2C04180g
uniprot id: Q6BVA3
names: Similarity
messages: Belongs to the TYW1 family.

284592:DEHA2F24904g
gene id: 284592:DEHA2F24904g
uniprot id: Q6BK49
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

284592:DEHA2F23122g
gene id: 284592:DEHA2F23122g
uniprot id: Q6BKC5
names: Similarity
messages: Belongs to the TCF25 family.

284592:DEHA2G17908g
gene id: 284592:DEHA2G17908g
uniprot id: Q6BHK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFT1 family.
messages: Nucleus
messages: RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Involved in poly(A) site recognition. May be involved in coupling transcription termination and mRNA 3'-end formation (By similarity).

284592:DEHA2C04312g
gene id: 284592:DEHA2C04312g
uniprot id: W0TYR2
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

284592:DEHA2F02156g
gene id: 284592:DEHA2F02156g
uniprot id: Q6BMW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

284592:DEHA2C12628g
gene id: 284592:DEHA2C12628g
uniprot id: Q6BU95
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autoacetylation at Lys-292 is required for proper function.
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z (By similarity). Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, and histone H2A to form H2AK4ac and H2AK7ac (By similarity). The NuA4 complex is involved in the DNA damage response and is required for chromosome segregation. The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) through homologous recombination (By similarity). Recruitment to promoters depends on H3K4me. Also acetylates non-histone proteins (By similarity). In addition to protein acetyltransferase, can use different acyl-CoA substrates, such as 2-hydroxyisobutanoyl-CoA (2-hydroxyisobutyryl-CoA) or (2E)-butenoyl-CoA (crotonyl-CoA), and is able to mediate protein 2-hydroxyisobutyrylation and crotonylation, respectively (By similarity).
messages: Chromosome
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus
messages: The ESA1-RPD3 motif is common to ESA1 and RPD3 and is required for ESA1 histone acetyl-transferase (HAT) activity and RPD3 histone deacetylase (HDAC) activity.

284592:DEHA2F01276g
gene id: 284592:DEHA2F01276g
uniprot id: Q6BN02
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

284592:DEHA2G24442g
gene id: 284592:DEHA2G24442g
uniprot id: Q6BGR7
names: Similarity
messages: Belongs to the CSN12 family.

284592:DEHA2G04268g
gene id: 284592:DEHA2G04268g
uniprot id: Q6BJ89
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

284592:DEHA2C14322g
gene id: 284592:DEHA2C14322g
uniprot id: Q6BU14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle. Interacts with NOP7 and RRP1. Interacts with RSA4 (via WD repeats).
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity).
messages: nucleolus

284592:DEHA2B16214g
gene id: 284592:DEHA2B16214g
uniprot id: Q6BVW3
names: Similarity
messages: Belongs to the catalase family.

284592:DEHA2F17160g
gene id: 284592:DEHA2F17160g
uniprot id: Q6BL14
names: Similarity
messages: Belongs to the UPF0045 family.

284592:DEHA2G21032g
gene id: 284592:DEHA2G21032g
uniprot id: Q6BH64
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

284592:DEHA2G15422g
gene id: 284592:DEHA2G15422g
uniprot id: Q6BHV8
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL39 family.
messages: Interacts with YIH1.

284592:DEHA2C13728g
gene id: 284592:DEHA2C13728g
uniprot id: B5RTB4
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

284592:DEHA2G18788g
gene id: 284592:DEHA2G18788g
uniprot id: Q6BHG5
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily.

284592:DEHA2C17270g
gene id: 284592:DEHA2C17270g
uniprot id: B5RTD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation.
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2G06468g
gene id: 284592:DEHA2G06468g
uniprot id: Q6BIZ3
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284592:DEHA2A03080g
gene id: 284592:DEHA2A03080g
uniprot id: Q6BZ92
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2B07986g
gene id: 284592:DEHA2B07986g
uniprot id: Q6BWW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.
messages: Nucleus

284592:DEHA2G19360g
gene id: 284592:DEHA2G19360g
uniprot id: Q6BHE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284592:DEHA2F12210g
gene id: 284592:DEHA2F12210g
uniprot id: Q6BLM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

284592:DEHA2A03234g
gene id: 284592:DEHA2A03234g
uniprot id: Q6BZ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL54 family.
messages: Mitochondrion

284592:DEHA2G20218g
gene id: 284592:DEHA2G20218g
uniprot id: Q6BHA0
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit. Interacts with pstB2. This interaction may be a means to structurally tether the donor membrane (ER) harboring PstB2 to acceptor membranes (Golgi/endosomes) harboring PSD2 during PtdSer transport to the site of PtdEtn synthesis.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: The C2 domains have an essential, but non-catalytic function. They may facilitate interaction with PstB2 and are required for lipid transport function.

284592:DEHA2C14938g
gene id: 284592:DEHA2C14938g
uniprot id: Q6BTY6
names: Similarity
messages: Belongs to the SH3YL1 family.

284592:DEHA2E20856g
gene id: 284592:DEHA2E20856g
uniprot id: Q6BNL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PAN1 family.
messages: Cell membrane
messages: Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
messages: Component of the PAN1 actin cytoskeleton-regulatory complex.
messages: Endosome membrane
messages: actin patch

284592:DEHA2B09900g
gene id: 284592:DEHA2B09900g
uniprot id: Q6BWN7
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

284592:DEHA2A02728g
gene id: 284592:DEHA2A02728g
uniprot id: Q6BZB1
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2B08932g
gene id: 284592:DEHA2B08932g
uniprot id: Q6BWS5
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2B06226g
gene id: 284592:DEHA2B06226g
uniprot id: Q6BX38
names: Similarity
messages: Belongs to the band 7/mec-2 family.

284592:DEHA2F24288g
gene id: 284592:DEHA2F24288g
uniprot id: B5RUN0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

284592:DEHA2A00748g
gene id: 284592:DEHA2A00748g
uniprot id: B5RSN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

284592:DEHA2A11594g
gene id: 284592:DEHA2A11594g
uniprot id: Q6BY82
names: Similarity
messages: Belongs to the VAC14 family.

284592:DEHA2E02244g
gene id: 284592:DEHA2E02244g
uniprot id: B5RTT1
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F09350g
gene id: 284592:DEHA2F09350g
uniprot id: Q6BM04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
messages: Chromosome
messages: Histone methyltransferase that trimethylates histone H3 'Lys-36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression.
messages: Nucleus
messages: The AWS and SET domains are necessary for transcription repression.

284592:DEHA2B04598g
gene id: 284592:DEHA2B04598g
uniprot id: Q6BXA7
names: Similarity
messages: Belongs to the MT-A70-like family.

284592:DEHA2F16390g
gene id: 284592:DEHA2F16390g
uniprot id: Q6BL50
names: Similarity
messages: Belongs to the KRI1 family.

284592:DEHA2A06996g
gene id: 284592:DEHA2A06996g
uniprot id: Q6BYU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC24 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284592:DEHA2B07612g
gene id: 284592:DEHA2B07612g
uniprot id: Q6BWX9
names: Similarity
messages: Belongs to the allantoicase family.

284592:DEHA2F11726g
gene id: 284592:DEHA2F11726g
uniprot id: Q6BLP8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

284592:DEHA2C14718g
gene id: 284592:DEHA2C14718g
uniprot id: Q6BTZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NBP35 and two labile, bridging clusters between subunits of the NBP35-CFD1 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export.
messages: Cytoplasm
messages: Heterotetramer of 2 NBP35 and 2 CFD1 chains.
messages: Nucleus

284592:DEHA2A06490g
gene id: 284592:DEHA2A06490g
uniprot id: Q6BYW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

284592:DEHA2E20812g
gene id: 284592:DEHA2E20812g
uniprot id: Q6BNL3
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G15554g
gene id: 284592:DEHA2G15554g
uniprot id: Q6BHV2
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G24134g
gene id: 284592:DEHA2G24134g
uniprot id: Q6BGT2
names: Similarity
messages: Belongs to the cyclin family.

284592:DEHA2F10626g
gene id: 284592:DEHA2F10626g
uniprot id: Q6BLU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA (By similarity). The NAD-cap is present at the 5'-end of some RNAs and snoRNAs. In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay (By similarity). Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs (By similarity). Has decapping activity toward incomplete 5'-end m7G cap mRNAs such as unmethylated 5'-end-capped RNA (cap0), while it has no activity toward 2'-O-ribose methylated m7G cap (cap1) (By similarity).
messages: Divalent metal cation.
messages: Nucleus

284592:DEHA2E12606g
gene id: 284592:DEHA2E12606g
uniprot id: Q6BPL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat ASA1 family.
messages: Component of the ASTRA chromatin remodeling machinery complex.
messages: Component of the ASTRA complex involved in chromatin remodeling.
messages: Nucleus

284592:DEHA2C04510g
gene id: 284592:DEHA2C04510g
uniprot id: Q6BV88
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

284592:DEHA2G05302g
gene id: 284592:DEHA2G05302g
uniprot id: B5RV37
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C09152g
gene id: 284592:DEHA2C09152g
uniprot id: Q6BUP4
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

284592:DEHA2E11352g
gene id: 284592:DEHA2E11352g
uniprot id: Q6BPR8
names: Similarity
messages: Belongs to the SF3A3 family.

284592:DEHA2E24244g
gene id: 284592:DEHA2E24244g
uniprot id: Q6BN65
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284592:DEHA2D12122g
gene id: 284592:DEHA2D12122g
uniprot id: Q6BS23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

284592:DEHA2F00352g
gene id: 284592:DEHA2F00352g
uniprot id: Q6BN44
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G04488g
gene id: 284592:DEHA2G04488g
uniprot id: Q6BJ80
names: Similarity
messages: Belongs to the thioredoxin family.

284592:DEHA2C10670g
gene id: 284592:DEHA2C10670g
uniprot id: B5RT96
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

284592:DEHA2F08580g
gene id: 284592:DEHA2F08580g
uniprot id: Q6BM36
names: Similarity
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.

284592:DEHA2A01562g
gene id: 284592:DEHA2A01562g
uniprot id: Q6BZG3
names: Function
names: Similarity
messages: Belongs to the AB hydrolase superfamily.
messages: Demethylates proteins that have been reversibly carboxymethylated. Demethylates the phosphatase PP2A catalytic subunit (By similarity).

284592:DEHA2F21494g
gene id: 284592:DEHA2F21494g
uniprot id: Q6BKJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

284592:DEHA2B04554g
gene id: 284592:DEHA2B04554g
uniprot id: Q6BXA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

284592:DEHA2A14102g
gene id: 284592:DEHA2A14102g
uniprot id: Q6BXX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS4/SLD5 family.
messages: Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation (By similarity).

284592:DEHA2C01914g
gene id: 284592:DEHA2C01914g
uniprot id: Q6BVK5
names: Similarity
messages: Belongs to the glycosyltransferase 34 family.

284592:DEHA2G12782g
gene id: 284592:DEHA2G12782g
uniprot id: B5RUR7
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E06754g
gene id: 284592:DEHA2E06754g
uniprot id: Q6BQB8
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

284592:DEHA2E18612g
gene id: 284592:DEHA2E18612g
uniprot id: Q6BNV9
names: Similarity
messages: Belongs to the cytochrome P450 family.

284592:DEHA2D08866g
gene id: 284592:DEHA2D08866g
uniprot id: B5RTF6
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

284592:DEHA2A08910g
gene id: 284592:DEHA2A08910g
uniprot id: Q6BYK2
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2D13222g
gene id: 284592:DEHA2D13222g
uniprot id: Q6BRX1
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
messages: Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.

284592:DEHA2F01430g
gene id: 284592:DEHA2F01430g
uniprot id: Q6BMZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX9 family.
messages: Interacts with the 35S, 23S and 20S pre-rRNAs and with the U3 snoRNA.
messages: Involved in ribosome biogenesis. Required for normal pre-rRNA processing in internal transcribed spacer 1 (ITS1). May be involved in the movements of the replication forks (By similarity).
messages: nucleolus

284592:DEHA2E05654g
gene id: 284592:DEHA2E05654g
uniprot id: Q6BQF3
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

284592:DEHA2F10296g
gene id: 284592:DEHA2F10296g
uniprot id: Q6BLV9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

284592:DEHA2B00220g
gene id: 284592:DEHA2B00220g
uniprot id: Q6BXU2
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D01078g
gene id: 284592:DEHA2D01078g
uniprot id: Q6BTF4
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2A06050g
gene id: 284592:DEHA2A06050g
uniprot id: Q6BYY3
names: Similarity
messages: Belongs to the AAR2 family.

284592:DEHA2E04972g
gene id: 284592:DEHA2E04972g
uniprot id: B5RTV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

284592:DEHA2D17226g
gene id: 284592:DEHA2D17226g
uniprot id: Q6BRD7
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2A13552g
gene id: 284592:DEHA2A13552g
uniprot id: Q6BY01
names: Similarity
messages: Belongs to the VPS52 family.

284592:DEHA2E22924g
gene id: 284592:DEHA2E22924g
uniprot id: Q6BNC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex SPC34 family.
messages: Nucleus
messages: kinetochore
messages: spindle

284592:DEHA2B02684g
gene id: 284592:DEHA2B02684g
uniprot id: W0TYQ7
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

284592:DEHA2F22264g
gene id: 284592:DEHA2F22264g
uniprot id: Q6BKG0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endopolyphosphatase PPN1 family.
messages: Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.
messages: Processing by proteases in the vacuole may be required for activation.
messages: Vacuole membrane

284592:DEHA2B06864g
gene id: 284592:DEHA2B06864g
uniprot id: Q6BX12
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

284592:DEHA2C08426g
gene id: 284592:DEHA2C08426g
uniprot id: Q6BUS5
names: Similarity
messages: Belongs to the cullin family.

284592:DEHA2B02024g
gene id: 284592:DEHA2B02024g
uniprot id: Q6BXL4
names: Similarity
messages: Belongs to the taffazin family.

284592:DEHA2D08008g
gene id: 284592:DEHA2D08008g
uniprot id: Q6BSL2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

284592:DEHA2C17050g
gene id: 284592:DEHA2C17050g
uniprot id: Q6BTN9
names: Similarity
messages: Belongs to the BolA/IbaG family.

284592:DEHA2F01298g
gene id: 284592:DEHA2F01298g
uniprot id: Q6BN01
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

284592:DEHA2D08052g
gene id: 284592:DEHA2D08052g
uniprot id: Q6BSL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cell membrane

284592:DEHA2D13266g
gene id: 284592:DEHA2D13266g
uniprot id: Q6BRW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

284592:DEHA2E04004g
gene id: 284592:DEHA2E04004g
uniprot id: Q6BQM3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: Phosphorylation at Ser-174 and Ser-175 promotes nuclear export.
messages: nucleolus

284592:DEHA2F09724g
gene id: 284592:DEHA2F09724g
uniprot id: Q6BLY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

284592:DEHA2E04598g
gene id: 284592:DEHA2E04598g
uniprot id: Q6BQK0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

284592:DEHA2G05038g
gene id: 284592:DEHA2G05038g
uniprot id: Q6BJ56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

284592:DEHA2C04158g
gene id: 284592:DEHA2C04158g
uniprot id: Q6BVA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Endoplasmic reticulum membrane
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.

284592:DEHA2C12078g
gene id: 284592:DEHA2C12078g
uniprot id: B5RTA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNN1/MNT family.
messages: Golgi apparatus membrane
messages: Membrane

284592:DEHA2B09284g
gene id: 284592:DEHA2B09284g
uniprot id: Q6BWR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2E13156g
gene id: 284592:DEHA2E13156g
uniprot id: Q6BPJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrion-specific ribosomal protein mS37 family.
messages: Component of the mitochondrial small ribosomal subunit.
messages: Involved in mitochondrial genome encoded proteins translation.
messages: Mitochondrion

284592:DEHA2A04708g
gene id: 284592:DEHA2A04708g
uniprot id: Q6BZ43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family.
messages: Mitochondrion
messages: N-acetylglutamate synthase involved in arginine biosynthesis.

284592:DEHA2A12254g
gene id: 284592:DEHA2A12254g
uniprot id: B5RSV0
names: Similarity
messages: Belongs to the glycosyl hydrolase 15 family.

284592:DEHA2G23826g
gene id: 284592:DEHA2G23826g
uniprot id: Q6BGU6
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

284592:DEHA2F14322g
gene id: 284592:DEHA2F14322g
uniprot id: Q6BLD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

284592:DEHA2A13750g
gene id: 284592:DEHA2A13750g
uniprot id: Q6BXZ2
names: Similarity
messages: Belongs to the biotin--protein ligase family.

284592:DEHA2E00726g
gene id: 284592:DEHA2E00726g
uniprot id: Q6BR10
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284592:DEHA2E04730g
gene id: 284592:DEHA2E04730g
uniprot id: Q6BQJ5
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284592:DEHA2B07722g
gene id: 284592:DEHA2B07722g
uniprot id: Q6BWX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family.
messages: Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. Binding to F-actin is regulated by tropomyosin. It is the major component of intranuclear and cytoplasmic actin rods. Required for accumulation of actin at the cell division site via depolymerizing actin at the cell ends. In association with myosin II has a role in the assembly of the contractile ring via severing actin filaments. Involved in the maintenance of the contractile ring once formed. In association with profilin and capping protein, has a role in the mitotic reorganization of the actin cytoskeleton (By similarity).
messages: Cytoplasm
messages: Nucleus matrix
messages: cytoskeleton

284592:DEHA2E08624g
gene id: 284592:DEHA2E08624g
uniprot id: Q6BQ38
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

284592:DEHA2B16280g
gene id: 284592:DEHA2B16280g
uniprot id: Q6BVW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2G13068g
gene id: 284592:DEHA2G13068g
uniprot id: Q6BI65
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

284592:DEHA2B11220g
gene id: 284592:DEHA2B11220g
uniprot id: Q6BWI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.

284592:DEHA2B10648g
gene id: 284592:DEHA2B10648g
uniprot id: Q6BWK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Mitochondrion inner membrane
messages: Probably involved in the biogenesis of the COX complex.

284592:DEHA2C16324g
gene id: 284592:DEHA2C16324g
uniprot id: Q6BTS2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

284592:DEHA2D07744g
gene id: 284592:DEHA2D07744g
uniprot id: Q6BSM3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits. Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA. Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5.8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.
messages: Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
messages: Component of pre-60S ribosomal complexes.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284592:DEHA2G09878g
gene id: 284592:DEHA2G09878g
uniprot id: Q6BIJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS9 family.
messages: Mitochondrion

284592:DEHA2E10098g
gene id: 284592:DEHA2E10098g
uniprot id: Q6BPX5
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D01694g
gene id: 284592:DEHA2D01694g
uniprot id: Q6BTC8
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
messages: Nucleus
messages: Ubiquitination of histone H2B to form H2BK123ub1 is required for efficient DOT1 methyltransferase activity on histone H3.

284592:DEHA2F24750g
gene id: 284592:DEHA2F24750g
uniprot id: Q6BK56
names: Similarity
messages: Belongs to the eIF-2-alpha family.

284592:DEHA2F25696g
gene id: 284592:DEHA2F25696g
uniprot id: Q6BK15
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2F20878g
gene id: 284592:DEHA2F20878g
uniprot id: Q6BKL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

284592:DEHA2F00748g
gene id: 284592:DEHA2F00748g
uniprot id: Q6BN28
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D04796g
gene id: 284592:DEHA2D04796g
uniprot id: Q6BSZ4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by C-terminal proteolytic cleavage by signaling protease (probably palB/RIM13) at neutral to alkaline ambient pH.
messages: Belongs to the pacC/RIM101 family.
messages: Binds to DNA. Interacts with RIM20, which binds to the two YPX[LI] motifs and is required for proteolytic processing (By similarity).
messages: Cytoplasm
messages: Nucleus
messages: Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including RIM101 itself) and represses transcription of acid-expressed genes (By similarity).

284592:DEHA2C06160g
gene id: 284592:DEHA2C06160g
uniprot id: Q6BV13
names: Similarity
messages: Belongs to the nucleoporin Nup133 family.

284592:DEHA2G21054g
gene id: 284592:DEHA2G21054g
uniprot id: Q6BH63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG16 family.
messages: Homodimer (By similarity). Part of the ATG5-ATG12/ATG16 complex. Several units of each may be present in this complex (By similarity).
messages: Preautophagosomal structure membrane
messages: Stabilizes the ATG5-ATG12 conjugate which is necessary for autophagy. The ATG5-ATG12/ATG16 complex is required for efficient promotion of ATG8-conjugation to phosphatidylethanolamine and ATG8 localization to the pre-autophagosomal structure (PAS). Recruits also ATG3 to the PAS. Involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress (By similarity).

284592:DEHA2C01760g
gene id: 284592:DEHA2C01760g
uniprot id: Q6BVL2
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

284592:DEHA2C03894g
gene id: 284592:DEHA2C03894g
uniprot id: Q6BVB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm

284592:DEHA2B02640g
gene id: 284592:DEHA2B02640g
uniprot id: Q6BXI6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

284592:DEHA2G00132g
gene id: 284592:DEHA2G00132g
uniprot id: Q6BJT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2E05500g
gene id: 284592:DEHA2E05500g
uniprot id: Q6BQG2
names: Similarity
messages: Belongs to the ATPase delta chain family.

284592:DEHA2G07744g
gene id: 284592:DEHA2G07744g
uniprot id: Q6BIT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

284592:DEHA2F22946g
gene id: 284592:DEHA2F22946g
uniprot id: Q6BKD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XLF subfamily.
messages: Nucleus

284592:DEHA2G18392g
gene id: 284592:DEHA2G18392g
uniprot id: Q6BHI1
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

284592:DEHA2E22286g
gene id: 284592:DEHA2E22286g
uniprot id: B5RU55
names: Similarity
messages: Belongs to the activator 1 small subunits family.

284592:DEHA2F15950g
gene id: 284592:DEHA2F15950g
uniprot id: W0TYU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane
messages: Required for vacuolar protein sorting.

284592:DEHA2G18216g
gene id: 284592:DEHA2G18216g
uniprot id: Q6BHI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity (By similarity).

284592:DEHA2F15378g
gene id: 284592:DEHA2F15378g
uniprot id: Q6BL92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2A11066g
gene id: 284592:DEHA2A11066g
uniprot id: Q6BYA5
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

284592:DEHA2B05588g
gene id: 284592:DEHA2B05588g
uniprot id: Q6BX66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: nucleolus

284592:DEHA2C12980g
gene id: 284592:DEHA2C12980g
uniprot id: Q6BU79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

284592:DEHA2B13574g
gene id: 284592:DEHA2B13574g
uniprot id: Q6BW83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.
messages: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate-binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions (By similarity).
messages: Heterodimer consisting of MSH2-MSH3 (MutS beta). Forms a ternary complex with MutL alpha (MLH1-PMS1) (By similarity).
messages: Nucleus

284592:DEHA2A06776g
gene id: 284592:DEHA2A06776g
uniprot id: Q6BYV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: Nucleus

284592:DEHA2E11726g
gene id: 284592:DEHA2E11726g
uniprot id: Q6BPQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTC4 family.
messages: May be involved in a process influencing telomere capping.
messages: Nucleus

284592:DEHA2E20416g
gene id: 284592:DEHA2E20416g
uniprot id: B5RU47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

284592:DEHA2B01122g
gene id: 284592:DEHA2B01122g
uniprot id: Q6BXQ5
names: Similarity
messages: Belongs to the GroES chaperonin family.

284592:DEHA2C00286g
gene id: 284592:DEHA2C00286g
uniprot id: Q6BVS4
names: Similarity
messages: Belongs to the FMO family.

284592:DEHA2B12056g
gene id: 284592:DEHA2B12056g
uniprot id: Q6BWE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

284592:DEHA2E11858g
gene id: 284592:DEHA2E11858g
uniprot id: Q6BPP6
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

284592:DEHA2G11682g
gene id: 284592:DEHA2G11682g
uniprot id: B5RUR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane

284592:DEHA2G15114g
gene id: 284592:DEHA2G15114g
uniprot id: Q6BHX3
names: Similarity
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer.

284592:DEHA2B04730g
gene id: 284592:DEHA2B04730g
uniprot id: Q6BXA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2F07898g
gene id: 284592:DEHA2F07898g
uniprot id: Q6BM68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport.

284592:DEHA2F19382g
gene id: 284592:DEHA2F19382g
uniprot id: Q6BKT4
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
messages: Heterodimer of an alpha and a beta chain.
messages: Mitochondrion matrix
messages: The alpha and beta chains are autoproteolytically processed from a single precursor protein within the mitochondrion.
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

284592:DEHA2D04576g
gene id: 284592:DEHA2D04576g
uniprot id: Q6BT05
names: Similarity
messages: Belongs to the FAH family.

284592:DEHA2C04466g
gene id: 284592:DEHA2C04466g
uniprot id: Q6BV90
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2G23584g
gene id: 284592:DEHA2G23584g
uniprot id: Q6BGV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

284592:DEHA2B11308g
gene id: 284592:DEHA2B11308g
uniprot id: Q6BWH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the cyclophilin-type PPIase family. CWC27 subfamily.
messages: Cytoplasm
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in pre-mRNA splicing (By similarity).

284592:DEHA2E20944g
gene id: 284592:DEHA2E20944g
uniprot id: Q9UV50
names: Activity Regulation
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Activated by tyrosine and threonine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.
messages: Cytoplasm
messages: Dually phosphorylated on Thr-174 and Tyr-176, which activates the enzyme (By similarity). Phosphorylated in response of osmotic stress, oxidative stress and UV stress, but not heat stress.
messages: Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes.
messages: Nucleus
messages: The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.

284592:DEHA2E10978g
gene id: 284592:DEHA2E10978g
uniprot id: Q6BPT5
names: Similarity
messages: Belongs to the EFG1/PHD1/stuA family.

284592:DEHA2E07018g
gene id: 284592:DEHA2E07018g
uniprot id: Q6BQA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: cis-Golgi network

284592:DEHA2E11484g
gene id: 284592:DEHA2E11484g
uniprot id: Q6BPR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.

284592:DEHA2D14432g
gene id: 284592:DEHA2D14432g
uniprot id: B5RTI1
names: Similarity
messages: Belongs to the RutC family.

284592:DEHA2F21450g
gene id: 284592:DEHA2F21450g
uniprot id: Q6BKJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer or homoheptamer. Organized in a ring with a central cavity.
messages: Mitochondrion matrix

284592:DEHA2C10296g
gene id: 284592:DEHA2C10296g
uniprot id: Q6BUI9
names: Similarity
messages: Belongs to the peptidase S8 family. Furin subfamily.

284592:DEHA2G24816g
gene id: 284592:DEHA2G24816g
uniprot id: Q6BGQ1
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284592:DEHA2E09482g
gene id: 284592:DEHA2E09482g
uniprot id: Q6BQ02
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with TAH18. Interacts with MIA40.
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

284592:DEHA2D02134g
gene id: 284592:DEHA2D02134g
uniprot id: Q6BTB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

284592:DEHA2F19008g
gene id: 284592:DEHA2F19008g
uniprot id: Q6BKV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Mitochondrion inner membrane

284592:DEHA2D06974g
gene id: 284592:DEHA2D06974g
uniprot id: Q6BSQ5
names: Similarity
messages: Belongs to the Mo25 family.

284592:DEHA2G01518g
gene id: 284592:DEHA2G01518g
uniprot id: B5RV16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 3 (AP-3) is a heterotetramer.
messages: Belongs to the adaptor complexes large subunit family.
messages: Golgi apparatus
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.

284592:DEHA2A13112g
gene id: 284592:DEHA2A13112g
uniprot id: Q6BY20
names: Function
names: Similarity
messages: Belongs to the arrestin family. PalF/RIM8 subfamily.
messages: Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.

284592:DEHA2G02684g
gene id: 284592:DEHA2G02684g
uniprot id: Q6BJG1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284592:DEHA2D18194g
gene id: 284592:DEHA2D18194g
uniprot id: B5RTL4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds to both phosphatidylinositol (PI) and phosphatidylinositol 3,5-bisphosphate (PIP2).
messages: Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by ATG15 is critical to life span extension.
messages: Prevacuolar compartment membrane
messages: multivesicular body membrane

284592:DEHA2D14124g
gene id: 284592:DEHA2D14124g
uniprot id: Q6BRS8
names: Similarity
messages: Belongs to the IlvD/Edd family.

284592:DEHA2E10736g
gene id: 284592:DEHA2E10736g
uniprot id: Q6BPU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events (By similarity).
messages: Belongs to the COG6 family.
messages: Golgi apparatus membrane

284592:DEHA2C08822g
gene id: 284592:DEHA2C08822g
uniprot id: Q6BUQ8
names: Similarity
messages: Belongs to the PAT1 family.

284592:DEHA2B12540g
gene id: 284592:DEHA2B12540g
uniprot id: Q6BWB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM21 family.
messages: Involved in mitochondrial migration along actin filaments.
messages: actin patch

284592:DEHA2E03894g
gene id: 284592:DEHA2E03894g
uniprot id: Q6BQM7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

284592:DEHA2B08778g
gene id: 284592:DEHA2B08778g
uniprot id: Q6BWT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

284592:DEHA2F11418g
gene id: 284592:DEHA2F11418g
uniprot id: Q6BLR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus

284592:DEHA2G02816g
gene id: 284592:DEHA2G02816g
uniprot id: Q6BJF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.
messages: Cytoplasm
messages: Monomer.

284592:DEHA2B04708g
gene id: 284592:DEHA2B04708g
uniprot id: Q6BXA2
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

284592:DEHA2C01870g
gene id: 284592:DEHA2C01870g
uniprot id: Q6BVK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

284592:DEHA2F15224g
gene id: 284592:DEHA2F15224g
uniprot id: Q6BL99
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

284592:DEHA2E21384g
gene id: 284592:DEHA2E21384g
uniprot id: Q6BNI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglutaminase-like superfamily. PNGase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins (By similarity).

284592:DEHA2D11088g
gene id: 284592:DEHA2D11088g
uniprot id: Q6BS73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling. Specifically recognizes PEX5 monoubiquitinated at 'Cys-6', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel. Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5.
messages: Interacts with PEX1; forming the PEX1-PEX6 AAA ATPase complex, which is composed of a heterohexamer formed by a trimer of PEX1-PEX6 dimers.
messages: Peroxisome membrane
messages: cytosol

284592:DEHA2A00220g
gene id: 284592:DEHA2A00220g
uniprot id: Q6BZN0
names: Subcellular Location Annotation
messages: telomere

284592:DEHA2A12430g
gene id: 284592:DEHA2A12430g
uniprot id: Q6BY49
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

284592:DEHA2D17512g
gene id: 284592:DEHA2D17512g
uniprot id: Q6BRC2
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

284592:DEHA2E07722g
gene id: 284592:DEHA2E07722g
uniprot id: Q6BQ74
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

284592:DEHA2G16742g
gene id: 284592:DEHA2G16742g
uniprot id: Q6BHQ2
names: Function
names: Similarity
messages: Belongs to the IRC6 family.
messages: Involved in gross chromosomal rearrangements (GCRs) and telomere healing.

284592:DEHA2A06028g
gene id: 284592:DEHA2A06028g
uniprot id: Q6BYY4
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C07018g
gene id: 284592:DEHA2C07018g
uniprot id: Q6BUY2
names: Similarity
names: Subunit
messages: Belongs to the AlaDH/PNT family.
messages: Monomer.

284592:DEHA2E09922g
gene id: 284592:DEHA2E09922g
uniprot id: Q6BPY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Membrane

284592:DEHA2B04246g
gene id: 284592:DEHA2B04246g
uniprot id: Q6BXC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNU71 family.
messages: Component of the U1 snRNP particle, a subcomplex of the spliceosome.
messages: Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway (By similarity).
messages: Cytoplasm
messages: Nucleus

284592:DEHA2B12144g
gene id: 284592:DEHA2B12144g
uniprot id: Q6BWD7
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2A08514g
gene id: 284592:DEHA2A08514g
uniprot id: Q6BYM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM11 family.
messages: Membrane

284592:DEHA2F02244g
gene id: 284592:DEHA2F02244g
uniprot id: Q6BMV7
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

284592:DEHA2G13288g
gene id: 284592:DEHA2G13288g
uniprot id: Q6BI56
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

284592:DEHA2D11770g
gene id: 284592:DEHA2D11770g
uniprot id: Q6BS40
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2F26598g
gene id: 284592:DEHA2F26598g
uniprot id: Q6BJX6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity).
messages: Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
messages: P-body
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284592:DEHA2D16192g
gene id: 284592:DEHA2D16192g
uniprot id: Q6BRI1
names: Similarity
messages: Belongs to the group II decarboxylase family.

284592:DEHA2B08294g
gene id: 284592:DEHA2B08294g
uniprot id: Q6BWV2
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

284592:DEHA2A10494g
gene id: 284592:DEHA2A10494g
uniprot id: Q6BYD0
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

284592:DEHA2B09394g
gene id: 284592:DEHA2B09394g
uniprot id: Q6BWR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NOP16 family.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

284592:DEHA2E15444g
gene id: 284592:DEHA2E15444g
uniprot id: Q6BP93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

284592:DEHA2E05676g
gene id: 284592:DEHA2E05676g
uniprot id: Q6BQF2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

284592:DEHA2E18458g
gene id: 284592:DEHA2E18458g
uniprot id: Q6BNW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5' to 3' DNA replicative helicase recruited to paused replisomes to promote fork progression throughout nonhistone protein-DNA complexes, naturally occurring impediments that are encountered in each S phase where replication forks pauses. Required for timely replication of the telomere and subtelomeric DNA and for wild-type levels of telomeric silencing. Involved in DNA repair during stalled replication fork, regulation of fragile sites expression and essential for genome stability. Plays also a role in mtDNA replication. Has G-quadruplex (G4) unwinding activity and can suppress G4-induced genome instability when PIF1 levels are low.
messages: Belongs to the helicase family. PIF1 subfamily.
messages: Nucleus
messages: telomere

284592:DEHA2F15510g
gene id: 284592:DEHA2F15510g
uniprot id: Q6BL86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

284592:DEHA2E22770g
gene id: 284592:DEHA2E22770g
uniprot id: Q6BND0
names: Similarity
messages: Belongs to the MT-A70-like family.

284592:DEHA2B08954g
gene id: 284592:DEHA2B08954g
uniprot id: Q6BWS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with nucleolar pre-ribosomal particles.
messages: Belongs to the RSA3 family.
messages: Required for efficient biogenesis of the 60S ribosomal subunit.
messages: nucleolus

284592:DEHA2E08910g
gene id: 284592:DEHA2E08910g
uniprot id: Q6BQ25
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284592:DEHA2G04378g
gene id: 284592:DEHA2G04378g
uniprot id: Q6BJ85
names: Similarity
messages: Belongs to the CENP-X/MHF2 family.

284592:DEHA2A06380g
gene id: 284592:DEHA2A06380g
uniprot id: Q6BYW8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284592:DEHA2A10626g
gene id: 284592:DEHA2A10626g
uniprot id: Q6BYC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP25 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.
messages: DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
messages: nucleolus

284592:DEHA2E13310g
gene id: 284592:DEHA2E13310g
uniprot id: Q6BPI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

284592:DEHA2E14146g
gene id: 284592:DEHA2E14146g
uniprot id: Q6BPF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.
messages: nucleolus

284592:DEHA2A02552g
gene id: 284592:DEHA2A02552g
uniprot id: Q6BZB9
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

284592:DEHA2B07964g
gene id: 284592:DEHA2B07964g
uniprot id: Q6BWW7
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2D01826g
gene id: 284592:DEHA2D01826g
uniprot id: Q6BTC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi. Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (By similarity).
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

284592:DEHA2E24288g
gene id: 284592:DEHA2E24288g
uniprot id: Q6BN63
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284592:DEHA2D13948g
gene id: 284592:DEHA2D13948g
uniprot id: Q6BRT6
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

284592:DEHA2F03828g
gene id: 284592:DEHA2F03828g
uniprot id: Q6BMN8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

284592:DEHA2E07876g
gene id: 284592:DEHA2E07876g
uniprot id: Q6BQ68
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

284592:DEHA2D00440g
gene id: 284592:DEHA2D00440g
uniprot id: B5RTP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2F17446g
gene id: 284592:DEHA2F17446g
uniprot id: Q6BL01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the misato family.
messages: Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.
messages: Mitochondrion

284592:DEHA2C11968g
gene id: 284592:DEHA2C11968g
uniprot id: Q6BUC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

284592:DEHA2G19338g
gene id: 284592:DEHA2G19338g
uniprot id: Q6BHE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

284592:DEHA2B16456g
gene id: 284592:DEHA2B16456g
uniprot id: Q6BVV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284592:DEHA2F22836g
gene id: 284592:DEHA2F22836g
uniprot id: Q6BKD6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284592:DEHA2C14058g
gene id: 284592:DEHA2C14058g
uniprot id: Q6BU29
names: Similarity
messages: Belongs to the SUN family.

284592:DEHA2F01078g
gene id: 284592:DEHA2F01078g
uniprot id: Q6BN11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Probable transporter.
messages: Vacuole membrane

284592:DEHA2F13244g
gene id: 284592:DEHA2F13244g
uniprot id: B5RUG0
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G12452g
gene id: 284592:DEHA2G12452g
uniprot id: Q6BI96
names: Similarity
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

284592:DEHA2B02244g
gene id: 284592:DEHA2B02244g
uniprot id: B5RT28
names: Subcellular Location Annotation
messages: Cell surface

284592:DEHA2A05742g
gene id: 284592:DEHA2A05742g
uniprot id: Q6BYZ7
names: Similarity
messages: Belongs to the cytochrome b5 family.

284592:DEHA2B15180g
gene id: 284592:DEHA2B15180g
uniprot id: Q6BW10
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

284592:DEHA2E06600g
gene id: 284592:DEHA2E06600g
uniprot id: Q6BQC6
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

284592:DEHA2G02354g
gene id: 284592:DEHA2G02354g
uniprot id: Q6BJH6
names: Similarity
messages: Belongs to the peptidase M18 family.

284592:DEHA2G02662g
gene id: 284592:DEHA2G02662g
uniprot id: Q6BJG2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

284592:DEHA2C02046g
gene id: 284592:DEHA2C02046g
uniprot id: Q6BVK0
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

284592:DEHA2G16280g
gene id: 284592:DEHA2G16280g
uniprot id: Q6BHR8
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

284592:DEHA2E19778g
gene id: 284592:DEHA2E19778g
uniprot id: Q6BNQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284592:DEHA2C15180g
gene id: 284592:DEHA2C15180g
uniprot id: B5RTC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

284592:DEHA2E13750g
gene id: 284592:DEHA2E13750g
uniprot id: Q6BPG7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with the flavoprotein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

284592:DEHA2C05830g
gene id: 284592:DEHA2C05830g
uniprot id: Q6BV29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

284592:DEHA2G10340g
gene id: 284592:DEHA2G10340g
uniprot id: Q6BIH6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

284592:DEHA2E17446g
gene id: 284592:DEHA2E17446g
uniprot id: Q6BP10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase TRM13 family.
messages: Cytoplasm
messages: nucleolus
messages: tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

284592:DEHA2E19580g
gene id: 284592:DEHA2E19580g
uniprot id: Q6BNR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

284592:DEHA2G08492g
gene id: 284592:DEHA2G08492g
uniprot id: Q6BIQ5
names: Similarity
messages: Belongs to the NifU family.

284592:DEHA2B01584g
gene id: 284592:DEHA2B01584g
uniprot id: Q6BXN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku80 family.
messages: Nucleus
messages: telomere

284592:DEHA2D09614g
gene id: 284592:DEHA2D09614g
uniprot id: Q6BSD7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

284592:DEHA2B14212g
gene id: 284592:DEHA2B14212g
uniprot id: Q6BW56
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F07590g
gene id: 284592:DEHA2F07590g
uniprot id: Q6BM83
names: Similarity
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Tetramer of two alpha and two beta subunits.

284592:DEHA2F07238g
gene id: 284592:DEHA2F07238g
uniprot id: Q6BM98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
messages: Mitochondrion

284592:DEHA2B04422g
gene id: 284592:DEHA2B04422g
uniprot id: Q6BXB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion inner membrane
messages: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.

284592:DEHA2G16302g
gene id: 284592:DEHA2G16302g
uniprot id: Q6BHR7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

284592:DEHA2G22242g
gene id: 284592:DEHA2G22242g
uniprot id: Q6BH11
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G07084g
gene id: 284592:DEHA2G07084g
uniprot id: Q6BIW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

284592:DEHA2E02046g
gene id: 284592:DEHA2E02046g
uniprot id: Q6BQU8
names: Function
names: Similarity
messages: Belongs to the NPR3 family.
messages: Mediates inactivation of the TORC1 complex in response to amino acid starvation. Required for meiotic nuclear division (By similarity).

284592:DEHA2D16390g
gene id: 284592:DEHA2D16390g
uniprot id: Q6BRH2
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.

284592:DEHA2C14696g
gene id: 284592:DEHA2C14696g
uniprot id: Q6BTZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

284592:DEHA2F15642g
gene id: 284592:DEHA2F15642g
uniprot id: Q6BL81
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2A07194g
gene id: 284592:DEHA2A07194g
uniprot id: Q6BYT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

284592:DEHA2F20966g
gene id: 284592:DEHA2F20966g
uniprot id: Q6BKL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF7 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus

284592:DEHA2B08140g
gene id: 284592:DEHA2B08140g
uniprot id: Q6BWV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the fungal fatty acid synthetase subunit beta family.
messages: Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl-[acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase.
messages: [Alpha(6)beta(6)] hexamers of two multifunctional subunits (alpha and beta).

284592:DEHA2E17468g
gene id: 284592:DEHA2E17468g
uniprot id: Q6BP09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTP family.
messages: Involved in protein synthesis. Involved in microtubule stabilization (By similarity).
messages: cytoskeleton

284592:DEHA2E20262g
gene id: 284592:DEHA2E20262g
uniprot id: Q6BNN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex, which consists of NDC80, NUF2, SPC24 and SPC25.
messages: Nucleus
messages: kinetochore

284592:DEHA2G06292g
gene id: 284592:DEHA2G06292g
uniprot id: Q6BJ00
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2G16522g
gene id: 284592:DEHA2G16522g
uniprot id: Q6BHR2
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2G09372g
gene id: 284592:DEHA2G09372g
uniprot id: Q6BIL7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

284592:DEHA2E00242g
gene id: 284592:DEHA2E00242g
uniprot id: Q6BR33
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds to both phosphatidylinositol (PI) and phosphatidylinositol 3,5-bisphosphate (PIP2).
messages: Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by ATG15 is critical to life span extension.
messages: Prevacuolar compartment membrane
messages: multivesicular body membrane

284592:DEHA2G03718g
gene id: 284592:DEHA2G03718g
uniprot id: Q6BJB4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

284592:DEHA2F21252g
gene id: 284592:DEHA2F21252g
uniprot id: Q6BKJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

284592:DEHA2F16192g
gene id: 284592:DEHA2F16192g
uniprot id: Q6BL58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease (By similarity).

284592:DEHA2E03718g
gene id: 284592:DEHA2E03718g
uniprot id: Q6BQN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2D08778g
gene id: 284592:DEHA2D08778g
uniprot id: Q6BSH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I LYR family.
messages: Mitochondrion inner membrane

284592:DEHA2E21824g
gene id: 284592:DEHA2E21824g
uniprot id: Q6BNH0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

284592:DEHA2B14564g
gene id: 284592:DEHA2B14564g
uniprot id: Q6BW39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with RPS21.
messages: Cytoplasm
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.

284592:DEHA2E18546g
gene id: 284592:DEHA2E18546g
uniprot id: Q6BNW2
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

284592:DEHA2D15290g
gene id: 284592:DEHA2D15290g
uniprot id: Q6BRM3
names: Similarity
messages: Belongs to the PPP phosphatase family.

284592:DEHA2G13442g
gene id: 284592:DEHA2G13442g
uniprot id: Q6BI49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

284592:DEHA2D07018g
gene id: 284592:DEHA2D07018g
uniprot id: Q6BSQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

284592:DEHA2E04400g
gene id: 284592:DEHA2E04400g
uniprot id: Q6BQK9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Inhibited by organophosphorus esters.
messages: Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity).

284592:DEHA2G06974g
gene id: 284592:DEHA2G06974g
uniprot id: Q6BIX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Binds 1 AMP per subunit.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

284592:DEHA2D13398g
gene id: 284592:DEHA2D13398g
uniprot id: Q6BRW3
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

284592:DEHA2F17644g
gene id: 284592:DEHA2F17644g
uniprot id: Q6BKZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284592:DEHA2D16346g
gene id: 284592:DEHA2D16346g
uniprot id: Q6BRH4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

284592:DEHA2G13530g
gene id: 284592:DEHA2G13530g
uniprot id: Q6BI45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284592:DEHA2G01056g
gene id: 284592:DEHA2G01056g
uniprot id: Q6BJP1
names: Function
names: Similarity
messages: Belongs to the endosulfine family.
messages: Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.

284592:DEHA2G09174g
gene id: 284592:DEHA2G09174g
uniprot id: Q6BIM5
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

284592:DEHA2E11770g
gene id: 284592:DEHA2E11770g
uniprot id: Q6BPQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

284592:DEHA2C01078g
gene id: 284592:DEHA2C01078g
uniprot id: Q6BVP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

284592:DEHA2G22902g
gene id: 284592:DEHA2G22902g
uniprot id: B5RUY9
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

284592:DEHA2G09064g
gene id: 284592:DEHA2G09064g
uniprot id: Q6BIN0
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

284592:DEHA2F11022g
gene id: 284592:DEHA2F11022g
uniprot id: Q6BLS7
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

284592:DEHA2F20130g
gene id: 284592:DEHA2F20130g
uniprot id: Q6BKQ0
names: Similarity
messages: Belongs to the peptidase C48 family.

284592:DEHA2G05742g
gene id: 284592:DEHA2G05742g
uniprot id: Q6BJ25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
messages: Cytoplasm

284592:DEHA2F08646g
gene id: 284592:DEHA2F08646g
uniprot id: Q6BM33
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

284592:DEHA2E17314g
gene id: 284592:DEHA2E17314g
uniprot id: Q6BP15
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
messages: Component of the signal peptidase complex (SPC) composed of a catalytic subunit SEC11 and three accessory subunits SPC1, SPC2 and SPC3 (By similarity). The complex induces a local thinning of the ER membrane which is used to measure the length of the signal peptide (SP) h-region of protein substrates. This ensures the selectivity of the complex towards h-regions shorter than 18-20 amino acids (By similarity). SPC associates with the translocon complex (By similarity).
messages: Endoplasmic reticulum membrane
messages: The C-terminal short (CTS) helix is essential for catalytic activity. It may be accommodated as a transmembrane helix in the thinned membrane environment of the complex, similarly to the signal peptide in the complex substrates.

284592:DEHA2C08910g
gene id: 284592:DEHA2C08910g
uniprot id: Q6BUQ5
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

284592:DEHA2B01430g
gene id: 284592:DEHA2B01430g
uniprot id: Q6BXP1
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2A07040g
gene id: 284592:DEHA2A07040g
uniprot id: Q6BYT8
names: Similarity
messages: Belongs to the cytidylyltransferase family.

284592:DEHA2F00836g
gene id: 284592:DEHA2F00836g
uniprot id: Q6BN23
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer; composed of 3 copies of TIM8 and 3 copies of TIM13, named soluble 70 kDa complex. Associates with the TIM22 complex, whose core is composed of TIM22 and TIM54. Interacts with the transmembrane regions of multi-pass transmembrane proteins in transit (By similarity).
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8-TIM13 complex is non essential and only mediates the import of few proteins, while the predominant TIM9-TIM10 70 kDa complex is crucial and mediates the import of much more proteins (By similarity).
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. However, during the transit of TIM8 from cytoplasm into mitochondrion, the Cys residues probably coordinate zinc, thereby preventing folding and allowing its transfer across mitochondrial outer membrane (By similarity).

284592:DEHA2E12056g
gene id: 284592:DEHA2E12056g
uniprot id: Q6BPN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2E18832g
gene id: 284592:DEHA2E18832g
uniprot id: Q6BNV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2E05082g
gene id: 284592:DEHA2E05082g
uniprot id: Q6BQH9
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

284592:DEHA2F20108g
gene id: 284592:DEHA2F20108g
uniprot id: Q6BKQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YME2 family.
messages: Mitochondrion inner membrane
messages: Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape. Involved in the regulation of mtDNA nucleotide structure and number. May have a dispensable role in early maturation of pre-rRNA (By similarity).

284592:DEHA2F14674g
gene id: 284592:DEHA2F14674g
uniprot id: Q6BLC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2G10362g
gene id: 284592:DEHA2G10362g
uniprot id: Q6BIH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS41 family.
messages: Involved in telomere length regulation.
messages: Mitochondrion

284592:DEHA2B05566g
gene id: 284592:DEHA2B05566g
uniprot id: Q6BX67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: High-conductance magnesium-selective channel that mediates the influx of magnesium into the mitochondrial matrix. Essential for the splicing of mRNA group II introns in mitochondria by affecting mitochondrial magnesium concentrations, which are critical for group II intron splicing. It also suppresses a variety of mitochondrial intron mutations and its absence may disturb the assembly of mitochondrial membrane complexes.
messages: Homopentamer. Forms homooligomers. Interacts with MFM1.
messages: Mitochondrion inner membrane

284592:DEHA2D13508g
gene id: 284592:DEHA2D13508g
uniprot id: Q6BRV6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284592:DEHA2D04246g
gene id: 284592:DEHA2D04246g
uniprot id: Q6BT19
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2B07150g
gene id: 284592:DEHA2B07150g
uniprot id: Q6BX00
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.

284592:DEHA2C05434g
gene id: 284592:DEHA2C05434g
uniprot id: B5RT78
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C10538g
gene id: 284592:DEHA2C10538g
uniprot id: Q6BUH8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrion-specific ribosomal protein mS23 family.
messages: Component of the mitochondrial small ribosomal subunit.
messages: Mitochondrion

284592:DEHA2F15202g
gene id: 284592:DEHA2F15202g
uniprot id: Q6BLA0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

284592:DEHA2A06732g
gene id: 284592:DEHA2A06732g
uniprot id: B5RSR8
names: Similarity
messages: Belongs to the peptidase M24B family.

284592:DEHA2E20900g
gene id: 284592:DEHA2E20900g
uniprot id: Q6BNK9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

284592:DEHA2G06864g
gene id: 284592:DEHA2G06864g
uniprot id: Q6BIX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
messages: Cytoplasm

284592:DEHA2E13354g
gene id: 284592:DEHA2E13354g
uniprot id: Q6BPI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FYV7 family.
messages: Involved in the processing of the 20S pre-rRNA.
messages: nucleolus

284592:DEHA2F14058g
gene id: 284592:DEHA2F14058g
uniprot id: Q6BLE6
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

284592:DEHA2B03784g
gene id: 284592:DEHA2B03784g
uniprot id: Q6BXE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

284592:DEHA2F06226g
gene id: 284592:DEHA2F06226g
uniprot id: Q6BME0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

284592:DEHA2E20680g
gene id: 284592:DEHA2E20680g
uniprot id: Q6BNL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MGR1 family.
messages: Component of the mitochondrial inner membrane i-AAA protease complex required for mitochondrial inner membrane protein turnover.
messages: Component of the mitochondrial inner membrane i-AAA protease complex.
messages: Mitochondrion inner membrane

284592:DEHA2G18590g
gene id: 284592:DEHA2G18590g
uniprot id: Q6BHH3
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

284592:DEHA2A09372g
gene id: 284592:DEHA2A09372g
uniprot id: Q6BYI2
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

284592:DEHA2B11462g
gene id: 284592:DEHA2B11462g
uniprot id: Q6BWG8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

284592:DEHA2D04818g
gene id: 284592:DEHA2D04818g
uniprot id: Q6BSZ3
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

284592:DEHA2G14542g
gene id: 284592:DEHA2G14542g
uniprot id: Q6BHZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BIG1 family.
messages: Endoplasmic reticulum membrane
messages: Required for normal beta-1,6-glucan synthesis.

284592:DEHA2G13860g
gene id: 284592:DEHA2G13860g
uniprot id: B5RUS6
names: Similarity
messages: Belongs to the CBF/MAK21 family.

284592:DEHA2A09680g
gene id: 284592:DEHA2A09680g
uniprot id: Q6BYG7
names: Similarity
messages: Belongs to the protein kinase superfamily.

284592:DEHA2A13398g
gene id: 284592:DEHA2A13398g
uniprot id: Q6BY07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Diphosphomevalonate decarboxylase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway (By similarity). The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins (By similarity). Activity by the mevalonate kinase ERG12 first converts mevalonate into 5-phosphomevalonate. 5-phosphomevalonate is then further converted to 5-diphosphomevalonate by the phosphomevalonate kinase ERG8 (By similarity). The diphosphomevalonate decarboxylase MVD1/ERG19 then produces isopentenyl diphosphate (By similarity). The isopentenyl-diphosphate delta-isomerase IDI1 then catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity). Finally the farnesyl diphosphate synthase ERG20 catalyzes the sequential condensation of isopentenyl pyrophosphate with dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (By similarity).
messages: Homodimer.

284592:DEHA2C05236g
gene id: 284592:DEHA2C05236g
uniprot id: Q6BV55
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

284592:DEHA2B11176g
gene id: 284592:DEHA2B11176g
uniprot id: Q6BWI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN2 family.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2G11297g
gene id: 284592:DEHA2G11297g
uniprot id: B5RUQ6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

284592:DEHA2F05852g
gene id: 284592:DEHA2F05852g
uniprot id: Q6BMF5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284592:DEHA2C08690g
gene id: 284592:DEHA2C08690g
uniprot id: Q6BUR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RIX1/PELP1 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA and the nucleoplasmic transit of the pre-60S ribosomal subunits. Regulates pre-60S association of the critical remodeling factor MDN1.
messages: Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.
messages: Nucleus

284592:DEHA2D18568g
gene id: 284592:DEHA2D18568g
uniprot id: B5RTM3
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2F11616g
gene id: 284592:DEHA2F11616g
uniprot id: Q6BLQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity).
messages: Component of the U3 snoRNP particle. Binds to the C'/D and B/C motifs in U3 snoRNA. Component of the 25S U4/U6.U5 tri-snRNP particle, a subcomplex of the spliceosome. Binds to the 5' stem-loop of U4 snRNA (By similarity).
messages: nucleolus

284592:DEHA2F26224g
gene id: 284592:DEHA2F26224g
uniprot id: Q6BJZ1
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2B12584g
gene id: 284592:DEHA2B12584g
uniprot id: B5RSZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNN1/MNT family.
messages: Golgi apparatus membrane
messages: Membrane

284592:DEHA2G08184g
gene id: 284592:DEHA2G08184g
uniprot id: Q6BIR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

284592:DEHA2D15048g
gene id: 284592:DEHA2D15048g
uniprot id: Q6BRN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: Component of the eIF4F complex, which composition varies with external and internal environmental conditions. It is composed of at least eIF4A, eIF4E and eIF4G (By similarity).
messages: Cytoplasm
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284592:DEHA2C06336g
gene id: 284592:DEHA2C06336g
uniprot id: Q6BV07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

284592:DEHA2G04994g
gene id: 284592:DEHA2G04994g
uniprot id: Q6BJ58
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C04378g
gene id: 284592:DEHA2C04378g
uniprot id: Q6BV94
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in mitochondrial RNA metabolism. Required for maintenance of mitochondrial DNA (By similarity).
messages: Belongs to the DEAD box helicase family. MRH4 subfamily.
messages: Mitochondrion
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284592:DEHA2F01650g
gene id: 284592:DEHA2F01650g
uniprot id: Q6BMY5
names: Function
names: Subcellular Location Annotation
messages: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Membrane
messages: Mitochondrion inner membrane
messages: Nucleus

284592:DEHA2E23980g
gene id: 284592:DEHA2E23980g
uniprot id: Q6BN77
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

284592:DEHA2F26752g
gene id: 284592:DEHA2F26752g
uniprot id: Q6BJW9
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2G08316g
gene id: 284592:DEHA2G08316g
uniprot id: Q6BIR2
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

284592:DEHA2B11484g
gene id: 284592:DEHA2B11484g
uniprot id: Q6BWG7
names: Function
names: Subcellular Location Annotation
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus

284592:DEHA2F24794g
gene id: 284592:DEHA2F24794g
uniprot id: Q6BK54
names: Similarity
messages: Belongs to the MEMO1 family.

284592:DEHA2F26818g
gene id: 284592:DEHA2F26818g
uniprot id: Q6BJW6
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

284592:DEHA2D05544g
gene id: 284592:DEHA2D05544g
uniprot id: Q6BSW2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

284592:DEHA2G23716g
gene id: 284592:DEHA2G23716g
uniprot id: B5RV00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

284592:DEHA2F13618g
gene id: 284592:DEHA2F13618g
uniprot id: Q6BLG5
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

284592:DEHA2C08646g
gene id: 284592:DEHA2C08646g
uniprot id: Q6BUR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

284592:DEHA2A07326g
gene id: 284592:DEHA2A07326g
uniprot id: Q6BYS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

284592:DEHA2E21076g
gene id: 284592:DEHA2E21076g
uniprot id: Q6BNK0
names: Similarity
messages: Belongs to the PITHD1 family.

284592:DEHA2G14124g
gene id: 284592:DEHA2G14124g
uniprot id: Q6BI17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBP4 family.
messages: Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b (By similarity).
messages: Mitochondrion inner membrane

284592:DEHA2F21978g
gene id: 284592:DEHA2F21978g
uniprot id: Q6BKH3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily.
messages: Present with 1460 molecules/cell in log phase SD medium.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284592:DEHA2E03498g
gene id: 284592:DEHA2E03498g
uniprot id: B5RTT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD4 family.
messages: Nucleus
messages: kinetochore
messages: spindle

284592:DEHA2A01628g
gene id: 284592:DEHA2A01628g
uniprot id: Q6BZG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SPT5 family.
messages: Component of the SPT4-SPT5 complex. Interacts with RNA polymerase II (By similarity).
messages: Nucleus
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).

284592:DEHA2B06204g
gene id: 284592:DEHA2B06204g
uniprot id: Q6BX39
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

284592:DEHA2D13486g
gene id: 284592:DEHA2D13486g
uniprot id: Q6BRV7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

284592:DEHA2G06314g
gene id: 284592:DEHA2G06314g
uniprot id: Q6BIZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

284592:DEHA2F24002g
gene id: 284592:DEHA2F24002g
uniprot id: Q6BK86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Expected to bind 2 Fe(2+) ions per subunit.
messages: Membrane
messages: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.

284592:DEHA2D06776g
gene id: 284592:DEHA2D06776g
uniprot id: B5RTE0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC4 family.
messages: Mitochondrion intermembrane space
messages: The twin Cx9C motifs are involved in the recognition by the mitochondrial disulfide relay system.

284592:DEHA2F02772g
gene id: 284592:DEHA2F02772g
uniprot id: Q6BMT5
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

284592:DEHA2B16170g
gene id: 284592:DEHA2B16170g
uniprot id: Q6BVW5
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G17468g
gene id: 284592:DEHA2G17468g
uniprot id: Q6BHM2
names: Subcellular Location Annotation
messages: Cytoplasm

284592:DEHA2G05610g
gene id: 284592:DEHA2G05610g
uniprot id: Q6BJ31
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

284592:DEHA2C16082g
gene id: 284592:DEHA2C16082g
uniprot id: Q6BTT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

284592:DEHA2E15334g
gene id: 284592:DEHA2E15334g
uniprot id: Q6BP98
names: Similarity
messages: Belongs to the RPAP1 family.

284592:DEHA2D10252g
gene id: 284592:DEHA2D10252g
uniprot id: Q6BSA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Golgi apparatus membrane
messages: Probable serine protease.
messages: cis-Golgi network membrane

284592:DEHA2B03278g
gene id: 284592:DEHA2B03278g
uniprot id: Q6BXG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2E10472g
gene id: 284592:DEHA2E10472g
uniprot id: Q6BPV8
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

284592:DEHA2E11704g
gene id: 284592:DEHA2E11704g
uniprot id: Q6BPQ3
names: Function
names: Similarity
messages: Catalyzes three sequential steps of tetrahydrofolate biosynthesis.
messages: In the C-terminal section; belongs to the DHPS family.
messages: In the N-terminal section; belongs to the DHNA family.
messages: In the central section; belongs to the HPPK family.

284592:DEHA2F04620g
gene id: 284592:DEHA2F04620g
uniprot id: B5RU94
names: Function
messages: Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

284592:DEHA2B09526g
gene id: 284592:DEHA2B09526g
uniprot id: Q9HGI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. ERF3 subfamily.
messages: Cytoplasm
messages: Involved in translation termination. Stimulates the activity of ERF1. Binds guanine nucleotides.

284592:DEHA2F26136g
gene id: 284592:DEHA2F26136g
uniprot id: Q6BJZ5
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F12628g
gene id: 284592:DEHA2F12628g
uniprot id: Q6BLL0
names: Subcellular Location Annotation
messages: Mitochondrion

284592:DEHA2D02574g
gene id: 284592:DEHA2D02574g
uniprot id: Q6BT90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Component of the GSE complex.
messages: GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.

284592:DEHA2G14212g
gene id: 284592:DEHA2G14212g
uniprot id: Q6BI13
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

284592:DEHA2A09812g
gene id: 284592:DEHA2A09812g
uniprot id: B5RSU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

284592:DEHA2C03344g
gene id: 284592:DEHA2C03344g
uniprot id: Q6BVE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity).

284592:DEHA2A14300g
gene id: 284592:DEHA2A14300g
uniprot id: B5RSN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2B13112g
gene id: 284592:DEHA2B13112g
uniprot id: Q6BWA4
names: Similarity
messages: Belongs to the TOP6A family.

284592:DEHA2F12848g
gene id: 284592:DEHA2F12848g
uniprot id: Q6BLJ9
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. COT1 subfamily.
messages: Protein kinase that seems to play a role in the regulation of cell morphogenesis and proliferation.

284592:DEHA2E01364g
gene id: 284592:DEHA2E01364g
uniprot id: Q6BQY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2F26070g
gene id: 284592:DEHA2F26070g
uniprot id: Q6BJZ8
names: Function
names: Similarity
messages: Catalyzes the second and fifth step in the 'de novo' purine biosynthesis pathway; contains phosphoribosylamine--glycine ligase (GARS) and phosphoribosylformylglycinamidine cyclo-ligase (AIRS) activities.
messages: In the C-terminal section; belongs to the AIR synthase family.
messages: In the N-terminal section; belongs to the GARS family.

284592:DEHA2C00814g
gene id: 284592:DEHA2C00814g
uniprot id: Q6BVQ3
names: Similarity
messages: Belongs to the cytochrome P450 family.

284592:DEHA2E22814g
gene id: 284592:DEHA2E22814g
uniprot id: Q6BNC8
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C13464g
gene id: 284592:DEHA2C13464g
uniprot id: Q6BU55
names: Similarity
messages: Belongs to the NAD kinase family.

284592:DEHA2C13574g
gene id: 284592:DEHA2C13574g
uniprot id: Q6BU51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the ISY1 family.
messages: Cytoplasm
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284592:DEHA2G10472g
gene id: 284592:DEHA2G10472g
uniprot id: B5RUP8
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C09746g
gene id: 284592:DEHA2C09746g
uniprot id: Q6BUL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2G08426g
gene id: 284592:DEHA2G08426g
uniprot id: Q6BIQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

284592:DEHA2B11352g
gene id: 284592:DEHA2B11352g
uniprot id: Q6BWH4
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

284592:DEHA2B07524g
gene id: 284592:DEHA2B07524g
uniprot id: Q6BWY3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

284592:DEHA2G20482g
gene id: 284592:DEHA2G20482g
uniprot id: Q6BH88
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

284592:DEHA2B07018g
gene id: 284592:DEHA2B07018g
uniprot id: B5RSX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

284592:DEHA2G23452g
gene id: 284592:DEHA2G23452g
uniprot id: Q6BGW2
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

284592:DEHA2F12144g
gene id: 284592:DEHA2F12144g
uniprot id: Q6BLM9
names: Similarity
messages: Belongs to the AHA1 family.

284592:DEHA2F18656g
gene id: 284592:DEHA2F18656g
uniprot id: Q6BKW5
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the peptidase M67A family.

284592:DEHA2B11792g
gene id: 284592:DEHA2B11792g
uniprot id: Q6BWF3
names: Similarity
messages: Belongs to the RENT3 family.

284592:DEHA2G04796g
gene id: 284592:DEHA2G04796g
uniprot id: Q6BJ67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the VPS17 family.
messages: Component of the retromer complex.
messages: Plays a role in vesicular protein sorting.

284592:DEHA2E20064g
gene id: 284592:DEHA2E20064g
uniprot id: Q6BNP2
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G13002g
gene id: 284592:DEHA2G13002g
uniprot id: Q6BI68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DSS1/SEM1 family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Nucleus

284592:DEHA2F23430g
gene id: 284592:DEHA2F23430g
uniprot id: Q6BKB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: nucleolus

284592:DEHA2D13772g
gene id: 284592:DEHA2D13772g
uniprot id: Q6BRU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of the enzymatic activity (By similarity).
messages: Cytoplasm

284592:DEHA2G02464g
gene id: 284592:DEHA2G02464g
uniprot id: Q6BJH0
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

284592:DEHA2F17226g
gene id: 284592:DEHA2F17226g
uniprot id: Q6BL11
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2A09174g
gene id: 284592:DEHA2A09174g
uniprot id: Q6BYJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRT14 family.
messages: Involved in ribosome biogenesis, probably through modulation of rDNA transcription.
messages: nucleolus

284592:DEHA2D11286g
gene id: 284592:DEHA2D11286g
uniprot id: Q6BS64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Dus family. Dus3 subfamily.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs (By similarity). Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity).
messages: Cytoplasm
messages: Nucleus

284592:DEHA2A00726g
gene id: 284592:DEHA2A00726g
uniprot id: Q6BZK1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

284592:DEHA2D12562g
gene id: 284592:DEHA2D12562g
uniprot id: Q6BS02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

284592:DEHA2F15180g
gene id: 284592:DEHA2F15180g
uniprot id: Q6BLA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FES1 family.
messages: Cytoplasm
messages: Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins (By similarity).

284592:DEHA2B05786g
gene id: 284592:DEHA2B05786g
uniprot id: Q6BX57
names: Similarity
messages: Belongs to the peptidase S8 family.

284592:DEHA2G03168g
gene id: 284592:DEHA2G03168g
uniprot id: Q6BJD8
names: Function
names: Subcellular Location Annotation
messages: Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2G14784g
gene id: 284592:DEHA2G14784g
uniprot id: Q6BHY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
messages: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.

284592:DEHA2C13288g
gene id: 284592:DEHA2C13288g
uniprot id: Q6BU63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP46 family.
messages: Mitochondrion
messages: Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules.

284592:DEHA2C08030g
gene id: 284592:DEHA2C08030g
uniprot id: Q6BUU0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

284592:DEHA2A03190g
gene id: 284592:DEHA2A03190g
uniprot id: Q6BZ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNN1/MNT family.
messages: Golgi apparatus membrane
messages: Membrane

284592:DEHA2G09812g
gene id: 284592:DEHA2G09812g
uniprot id: Q6BIJ8
names: Similarity
messages: Belongs to the UPP synthase family.

284592:DEHA2F21384g
gene id: 284592:DEHA2F21384g
uniprot id: B5RUL1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

284592:DEHA2A11704g
gene id: 284592:DEHA2A11704g
uniprot id: Q6BY78
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

284592:DEHA2G05148g
gene id: 284592:DEHA2G05148g
uniprot id: Q6BJ51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAD52 family.
messages: Involved in DNA double-strand break (DSB) repair and recombination. Promotes the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase (By similarity).
messages: Nucleus
messages: Part of a complex that includes RAD51, RAD52 and RAD59.

284592:DEHA2C07194g
gene id: 284592:DEHA2C07194g
uniprot id: Q6BUX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

284592:DEHA2D09350g
gene id: 284592:DEHA2D09350g
uniprot id: Q6BSE9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

284592:DEHA2B01518g
gene id: 284592:DEHA2B01518g
uniprot id: Q6BXN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

284592:DEHA2F01320g
gene id: 284592:DEHA2F01320g
uniprot id: Q6BN00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IML1 family.
messages: Vacuole membrane

284592:DEHA2F11308g
gene id: 284592:DEHA2F11308g
uniprot id: Q6BLR5
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2D06842g
gene id: 284592:DEHA2D06842g
uniprot id: Q6BSR2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

284592:DEHA2A14322g
gene id: 284592:DEHA2A14322g
uniprot id: Q6BXW7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284592:DEHA2D11660g
gene id: 284592:DEHA2D11660g
uniprot id: Q6BS46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Golgi apparatus membrane
messages: Membrane

284592:DEHA2A01276g
gene id: 284592:DEHA2A01276g
uniprot id: Q6BZH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

284592:DEHA2G00902g
gene id: 284592:DEHA2G00902g
uniprot id: Q6BJP8
names: Similarity
messages: Belongs to the peptidase M14 family.

284592:DEHA2F25058g
gene id: 284592:DEHA2F25058g
uniprot id: Q6BK42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDI1 family.
messages: Binds ubiquitin and polyubiquitinated proteins.
messages: Cytoplasm
messages: Probable aspartic protease. May be involved in the regulation of exocytosis. Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation. Required for S-phase checkpoint control.

284592:DEHA2D03960g
gene id: 284592:DEHA2D03960g
uniprot id: Q6BT31
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG8 family.
messages: The C-terminal 20 residues are removed to expose Gly-116 at the C-terminus. The C-terminal Gly is then amidated with phosphatidylethanolamine by an activating system similar to that for ubiquitin.
messages: Ubiquitin-like modifier involved in autophagosomes formation. With ATG4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.
messages: Vacuole membrane
messages: autophagosome membrane

284592:DEHA2D07898g
gene id: 284592:DEHA2D07898g
uniprot id: Q6BSL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

284592:DEHA2G02200g
gene id: 284592:DEHA2G02200g
uniprot id: B5RV22
names: Similarity
messages: Belongs to the RMD1/sif2 family.

284592:DEHA2G23034g
gene id: 284592:DEHA2G23034g
uniprot id: B5RUY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm

284592:DEHA2C12870g
gene id: 284592:DEHA2C12870g
uniprot id: Q6BU84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC22 family.
messages: Cytoplasm
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284592:DEHA2E18942g
gene id: 284592:DEHA2E18942g
uniprot id: Q6BNU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

284592:DEHA2G03696g
gene id: 284592:DEHA2G03696g
uniprot id: Q6BJB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role (via N-terminus) in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. Further stabilizes spliceosome conformation for 3'-splice site docking (via C-terminus) promoting exon ligation.

284592:DEHA2F19074g
gene id: 284592:DEHA2F19074g
uniprot id: Q6BKU7
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2F21736g
gene id: 284592:DEHA2F21736g
uniprot id: Q6BKI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX20 family.
messages: Involved in the assembly of the cytochrome c oxidase complex.
messages: Mitochondrion inner membrane

284592:DEHA2F24860g
gene id: 284592:DEHA2F24860g
uniprot id: Q6BK51
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

284592:DEHA2C05192g
gene id: 284592:DEHA2C05192g
uniprot id: Q6BV57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BMT2 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA.
messages: nucleolus

284592:DEHA2B13332g
gene id: 284592:DEHA2B13332g
uniprot id: Q6BW94
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

284592:DEHA2F13046g
gene id: 284592:DEHA2F13046g
uniprot id: Q6BLJ0
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

284592:DEHA2E22550g
gene id: 284592:DEHA2E22550g
uniprot id: Q6BND9
names: Function
names: Similarity
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.

284592:DEHA2B04488g
gene id: 284592:DEHA2B04488g
uniprot id: Q6BXB2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: The heme is bound between the two transmembrane subunits.

284592:DEHA2E14234g
gene id: 284592:DEHA2E14234g
uniprot id: Q6BPE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2G04818g
gene id: 284592:DEHA2G04818g
uniprot id: Q6BJ66
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

284592:DEHA2F27082g
gene id: 284592:DEHA2F27082g
uniprot id: Q6BJV5
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D05412g
gene id: 284592:DEHA2D05412g
uniprot id: Q6BSW7
names: Function
names: Similarity
messages: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
messages: Belongs to the actin family.

284592:DEHA2C09240g
gene id: 284592:DEHA2C09240g
uniprot id: Q6BUP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. Fungal FIT2B/SCS3 subfamily.
messages: Endoplasmic reticulum membrane
messages: Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen. This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis. May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation. May play a role in the regulation of cell morphology and cytoskeletal organization. Involved in phospholipid biosynthesis.
messages: Membrane

284592:DEHA2F25564g
gene id: 284592:DEHA2F25564g
uniprot id: Q6BK20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Mitochondrion inner membrane

284592:DEHA2G08844g
gene id: 284592:DEHA2G08844g
uniprot id: Q6BIP0
names: Similarity
messages: Belongs to the peptidase C19 family.

284592:DEHA2B16368g
gene id: 284592:DEHA2B16368g
uniprot id: Q6BVV6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

284592:DEHA2B07744g
gene id: 284592:DEHA2B07744g
uniprot id: Q6BWX3
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

284592:DEHA2G05478g
gene id: 284592:DEHA2G05478g
uniprot id: Q6BJ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

284592:DEHA2E15290g
gene id: 284592:DEHA2E15290g
uniprot id: B5RU17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2F06402g
gene id: 284592:DEHA2F06402g
uniprot id: Q6BMD5
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

284592:DEHA2F13640g
gene id: 284592:DEHA2F13640g
uniprot id: Q6BLG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ALB1 family.
messages: Component of the nucleoplasmic and cytoplasmic pre-60S ribosomal particles.
messages: Cytoplasm
messages: Involved in proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit. Accompanies the pre-60S particles to the cytoplasm (By similarity).
messages: Nucleus

284592:DEHA2F13310g
gene id: 284592:DEHA2F13310g
uniprot id: Q6BLH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DASH complex DAD3 family.
messages: Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
messages: Nucleus
messages: The DASH complex oligomerizes to form rings that encircle the microtubules.
messages: kinetochore
messages: spindle

284592:DEHA2B09504g
gene id: 284592:DEHA2B09504g
uniprot id: B5RSZ1
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

284592:DEHA2B01078g
gene id: 284592:DEHA2B01078g
uniprot id: Q6BXQ7
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F09988g
gene id: 284592:DEHA2F09988g
uniprot id: Q6BLX2
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

284592:DEHA2C03234g
gene id: 284592:DEHA2C03234g
uniprot id: Q6BVE5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

284592:DEHA2D13970g
gene id: 284592:DEHA2D13970g
uniprot id: Q6BRT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CybS family.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2C05874g
gene id: 284592:DEHA2C05874g
uniprot id: Q6BV26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2B12518g
gene id: 284592:DEHA2B12518g
uniprot id: Q6BWC0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Facilitates protein transport into the nucleus. Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import (By similarity).

284592:DEHA2E02794g
gene id: 284592:DEHA2E02794g
uniprot id: B5RTT4
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E22638g
gene id: 284592:DEHA2E22638g
uniprot id: Q6BND5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Membrane

284592:DEHA2E05786g
gene id: 284592:DEHA2E05786g
uniprot id: Q6BQE6
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G01584g
gene id: 284592:DEHA2G01584g
uniprot id: Q6BJL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

284592:DEHA2F04796g
gene id: 284592:DEHA2F04796g
uniprot id: Q6BMK0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

284592:DEHA2C01562g
gene id: 284592:DEHA2C01562g
uniprot id: Q6BVL9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

284592:DEHA2G18700g
gene id: 284592:DEHA2G18700g
uniprot id: Q6BHG8
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

284592:DEHA2C03366g
gene id: 284592:DEHA2C03366g
uniprot id: Q6BVE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284592:DEHA2F01056g
gene id: 284592:DEHA2F01056g
uniprot id: Q6BN12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint (By similarity).

284592:DEHA2F05786g
gene id: 284592:DEHA2F05786g
uniprot id: Q6BMF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

284592:DEHA2E08052g
gene id: 284592:DEHA2E08052g
uniprot id: Q6BQ61
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent rRNA helicase required for pre-ribosomal RNA processing. Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
messages: Interacts with the SSU processome.
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284592:DEHA2F01716g
gene id: 284592:DEHA2F01716g
uniprot id: Q6BMY2
names: Similarity
messages: Belongs to the isochorismatase family.

284592:DEHA2D03498g
gene id: 284592:DEHA2D03498g
uniprot id: Q6BT50
names: Similarity
messages: Belongs to the TRL1 family.

284592:DEHA2B11440g
gene id: 284592:DEHA2B11440g
uniprot id: Q6BWH0
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

284592:DEHA2C14894g
gene id: 284592:DEHA2C14894g
uniprot id: Q6BTY8
names: Similarity
messages: Belongs to the CoA-transferase III family.

284592:DEHA2E18414g
gene id: 284592:DEHA2E18414g
uniprot id: B5RU38
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

284592:DEHA2C06358g
gene id: 284592:DEHA2C06358g
uniprot id: Q6BV06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
messages: Nucleus
messages: Serine/threonine-protein kinase involved in transcription regulation. Phosphorylates the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes. Also required for histone H3 methylation. Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase (By similarity).

284592:DEHA2E16918g
gene id: 284592:DEHA2E16918g
uniprot id: B5RU30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS10-related sortilin family.
messages: Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
messages: Prevacuolar compartment membrane
messages: trans-Golgi network membrane

284592:DEHA2E19404g
gene id: 284592:DEHA2E19404g
uniprot id: Q6BNS1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.
messages: Cytoplasm
messages: Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.
messages: Signal recognition particle consists of a 7S RNA molecule and at least six protein subunits.

284592:DEHA2G05192g
gene id: 284592:DEHA2G05192g
uniprot id: Q6BJ49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Involved in pre-mRNA splicing. Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site. Involved in cap modification.
messages: Nucleus

284592:DEHA2E06556g
gene id: 284592:DEHA2E06556g
uniprot id: Q6BQC8
names: Similarity
messages: Belongs to the hexokinase family.

284592:DEHA2D06061g
gene id: 284592:DEHA2D06061g
uniprot id: B5RTR8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

284592:DEHA2D02266g
gene id: 284592:DEHA2D02266g
uniprot id: Q6BTA4
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

284592:DEHA2F15114g
gene id: 284592:DEHA2F15114g
uniprot id: Q6BLA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

284592:DEHA2A11990g
gene id: 284592:DEHA2A11990g
uniprot id: Q6BY68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284592:DEHA2G13024g
gene id: 284592:DEHA2G13024g
uniprot id: Q6BI67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2G04708g
gene id: 284592:DEHA2G04708g
uniprot id: B5RV36
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2A11352g
gene id: 284592:DEHA2A11352g
uniprot id: Q6BY93
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284592:DEHA2F14344g
gene id: 284592:DEHA2F14344g
uniprot id: Q6BLD5
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-II family.

284592:DEHA2E11660g
gene id: 284592:DEHA2E11660g
uniprot id: Q6BPQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

284592:DEHA2E21846g
gene id: 284592:DEHA2E21846g
uniprot id: Q6BNG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.

284592:DEHA2A03102g
gene id: 284592:DEHA2A03102g
uniprot id: B5RSP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: May associate with the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.

284592:DEHA2F07744g
gene id: 284592:DEHA2F07744g
uniprot id: Q6BM74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GST superfamily.
messages: Homodimer.
messages: Plays an important role in the cellular response to the nitrogen source. URE2 gene plays a major part in the repression of GLN1 and GDH2 genes by glutamine, and is required for the inactivation of glutamine synthetase. URE2 gene product may catalytically inactivate GLN3 in response to an increase in the intracellular concentration of glutamine (By similarity).

284592:DEHA2B01914g
gene id: 284592:DEHA2B01914g
uniprot id: Q6BXL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284592:DEHA2G19448g
gene id: 284592:DEHA2G19448g
uniprot id: B5RUV7
names: Similarity
messages: Belongs to the DapA family.

284592:DEHA2E00660g
gene id: 284592:DEHA2E00660g
uniprot id: Q6BR13
names: Similarity
messages: Belongs to the DapA family.

284592:DEHA2A00880g
gene id: 284592:DEHA2A00880g
uniprot id: Q6BZJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

284592:DEHA2D18656g
gene id: 284592:DEHA2D18656g
uniprot id: Q6BR74
names: Similarity
messages: Belongs to the BLOC1S2 family.

284592:DEHA2G21450g
gene id: 284592:DEHA2G21450g
uniprot id: B5RUX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

284592:DEHA2G24926g
gene id: 284592:DEHA2G24926g
uniprot id: Q6BGP5
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C09658g
gene id: 284592:DEHA2C09658g
uniprot id: Q6BUL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

284592:DEHA2G21494g
gene id: 284592:DEHA2G21494g
uniprot id: Q6BH44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

284592:DEHA2C10868g
gene id: 284592:DEHA2C10868g
uniprot id: Q6BUG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2C17402g
gene id: 284592:DEHA2C17402g
uniprot id: Q6BTM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP46 family.
messages: Mitochondrion
messages: Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules.

284592:DEHA2G05082g
gene id: 284592:DEHA2G05082g
uniprot id: Q6BJ54
names: Similarity
messages: Belongs to the multicopper oxidase family.

284592:DEHA2F25850g
gene id: 284592:DEHA2F25850g
uniprot id: Q6BK08
names: Function
names: Similarity
messages: Belongs to the peptidase C13 family.
messages: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

284592:DEHA2B14960g
gene id: 284592:DEHA2B14960g
uniprot id: Q6BW21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminopeptidase that preferentially cleaves di- and tripeptides. Also has low epoxide hydrolase activity (in vitro). Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2B06622g
gene id: 284592:DEHA2B06622g
uniprot id: Q6BX22
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

284592:DEHA2B01870g
gene id: 284592:DEHA2B01870g
uniprot id: Q6BXM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BIG1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2B11264g
gene id: 284592:DEHA2B11264g
uniprot id: Q6BWH8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DP1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Oligomer.
messages: Required to generate and maintain the structure of the tubular endoplasmic reticulum network and the vacuole. Induces high curvature in membranes and causes membrane tubule formation. Involved in membrane/vesicle trafficking.
messages: The short lumenal loops between transmembrane domains 1 and 2 and between transmembrane domains 3 and 4 may impart a wedge-like configuration, thus deforming membranes.

284592:DEHA2C13376g
gene id: 284592:DEHA2C13376g
uniprot id: Q6BU59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

284592:DEHA2C08360g
gene id: 284592:DEHA2C08360g
uniprot id: Q6BUS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CHS7 family.
messages: Chaperone required for the export of the chitin synthase CHS3 from the endoplasmic reticulum.
messages: Endoplasmic reticulum membrane
messages: Interacts with CHS3.

284592:DEHA2E01474g
gene id: 284592:DEHA2E01474g
uniprot id: Q6BQX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: May be involved in the mitochondrial lipid metabolism.
messages: Mitochondrion
messages: nucleolus

284592:DEHA2C08096g
gene id: 284592:DEHA2C08096g
uniprot id: Q6BUT7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

284592:DEHA2G07590g
gene id: 284592:DEHA2G07590g
uniprot id: Q6BIU4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284592:DEHA2F15620g
gene id: 284592:DEHA2F15620g
uniprot id: B5RUH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO84 family.
messages: Vesicle
messages: secretory vesicle

284592:DEHA2E11286g
gene id: 284592:DEHA2E11286g
uniprot id: Q6BPS1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

284592:DEHA2F23386g
gene id: 284592:DEHA2F23386g
uniprot id: Q6BKB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

284592:DEHA2E10758g
gene id: 284592:DEHA2E10758g
uniprot id: Q6BPU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1.
messages: Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.
messages: Cytoplasm

284592:DEHA2A08932g
gene id: 284592:DEHA2A08932g
uniprot id: Q6BYK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the RSE1 family.
messages: Involved in pre-mRNA splicing and cell cycle control.
messages: Nucleus

284592:DEHA2F12100g
gene id: 284592:DEHA2F12100g
uniprot id: Q6BLN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

284592:DEHA2C15356g
gene id: 284592:DEHA2C15356g
uniprot id: Q6BTW7
names: Function
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.

284592:DEHA2E17490g
gene id: 284592:DEHA2E17490g
uniprot id: Q6BP08
names: Similarity
messages: Belongs to the peptidase S9B family.

284592:DEHA2D09152g
gene id: 284592:DEHA2D09152g
uniprot id: B5RTF8
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

284592:DEHA2G17974g
gene id: 284592:DEHA2G17974g
uniprot id: Q6BHK0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

284592:DEHA2E12298g
gene id: 284592:DEHA2E12298g
uniprot id: Q6BPM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

284592:DEHA2A11044g
gene id: 284592:DEHA2A11044g
uniprot id: Q6BYA6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

284592:DEHA2F26334g
gene id: 284592:DEHA2F26334g
uniprot id: Q6BJY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284592:DEHA2E15708g
gene id: 284592:DEHA2E15708g
uniprot id: Q6BP84
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. FKBP2 subfamily.
messages: Endoplasmic reticulum
messages: Inhibited by both FK506 and rapamycin.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

284592:DEHA2D18524g
gene id: 284592:DEHA2D18524g
uniprot id: Q6BR80
names: Similarity
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.

284592:DEHA2F03366g
gene id: 284592:DEHA2F03366g
uniprot id: Q6BMQ9
names: Similarity
messages: Belongs to the Nth/MutY family.

284592:DEHA2G07524g
gene id: 284592:DEHA2G07524g
uniprot id: Q6BIU7
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

284592:DEHA2B01958g
gene id: 284592:DEHA2B01958g
uniprot id: Q6BXL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. The complex is held together by ERB1, which interacts with NOP7 via its N-terminal domain and with YTM1 via a high-affinity interaction between the seven-bladed beta-propeller domains of the 2 proteins. The NOP7 complex associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

284592:DEHA2G05258g
gene id: 284592:DEHA2G05258g
uniprot id: Q6BJ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

284592:DEHA2E22902g
gene id: 284592:DEHA2E22902g
uniprot id: Q6BNC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2D02992g
gene id: 284592:DEHA2D02992g
uniprot id: Q6BT73
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2G12716g
gene id: 284592:DEHA2G12716g
uniprot id: Q6BI82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF1 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus

284592:DEHA2F22506g
gene id: 284592:DEHA2F22506g
uniprot id: Q6BKF0
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2A07942g
gene id: 284592:DEHA2A07942g
uniprot id: Q6BYP4
names: Similarity
messages: Belongs to the peptidase C19 family.

284592:DEHA2F24200g
gene id: 284592:DEHA2F24200g
uniprot id: Q6BK77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M76 family.
messages: Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity).
messages: Mitochondrion inner membrane

284592:DEHA2A12100g
gene id: 284592:DEHA2A12100g
uniprot id: Q6BY63
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.

284592:DEHA2F14982g
gene id: 284592:DEHA2F14982g
uniprot id: Q6BLB0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

284592:DEHA2F24772g
gene id: 284592:DEHA2F24772g
uniprot id: Q6BK55
names: Similarity
messages: Belongs to the Rho GDI family.

284592:DEHA2F03124g
gene id: 284592:DEHA2F03124g
uniprot id: Q6BMR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

284592:DEHA2F08008g
gene id: 284592:DEHA2F08008g
uniprot id: B5RUB9
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

284592:DEHA2G12364g
gene id: 284592:DEHA2G12364g
uniprot id: Q6BIA1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PROPPIN family.
messages: Contains a beta-propeller domain involved in specific binding to phosphatidylinositol 3,5-bisphosphate (PIP2).
messages: Cytoplasm
messages: Membrane
messages: Required for cytoplasm to vacuole transport (Cvt) vesicles formation and mitophagy. Involved in binding of phosphatidylethanolamine to ATG8 and in recruitment of ATG8 and ATG5 to the pre-autophagosomal structure. Protects ATG8 from ARG4-mediated cleavage (By similarity).
messages: The L/FRRG motif is essential for the cytoplasm to vacuole transport (Cvt) pathway and for the recruitment of ATG8 and ATG16 to the PAS in nutrient-rich medium and in both its recruitment to and dissociation from the PAS under starvation conditions.
messages: Vacuole membrane

284592:DEHA2F14234g
gene id: 284592:DEHA2F14234g
uniprot id: Q6BLD8
names: Similarity
messages: Belongs to the GET4 family.

284592:DEHA2A10318g
gene id: 284592:DEHA2A10318g
uniprot id: Q6BYD9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of a heterotrimeric complex containing IMP3, IMP4 and MPP10.
messages: Component of the U3 small nucleolar ribonucleoprotein. Required for the early cleavages at sites A0, A1 and A2 during 18S ribosomal pre-RNA processing (By similarity).
messages: nucleolus

284592:DEHA2F23342g
gene id: 284592:DEHA2F23342g
uniprot id: Q6BKB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

284592:DEHA2G04576g
gene id: 284592:DEHA2G04576g
uniprot id: Q6BJ77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.
messages: cis-Golgi network

284592:DEHA2A03014g
gene id: 284592:DEHA2A03014g
uniprot id: Q6BZ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Membrane
messages: Mitochondrion outer membrane

284592:DEHA2F09614g
gene id: 284592:DEHA2F09614g
uniprot id: Q6BLZ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).
messages: Cytoplasm

284592:DEHA2C15994g
gene id: 284592:DEHA2C15994g
uniprot id: Q6BTT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

284592:DEHA2C05918g
gene id: 284592:DEHA2C05918g
uniprot id: Q6BV24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2G13420g
gene id: 284592:DEHA2G13420g
uniprot id: Q6BI50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane
messages: Regulates also the sphingolipid metabolism.

284592:DEHA2C12342g
gene id: 284592:DEHA2C12342g
uniprot id: Q6BUA8
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

284592:DEHA2D13706g
gene id: 284592:DEHA2D13706g
uniprot id: Q6BRU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

284592:DEHA2D18942g
gene id: 284592:DEHA2D18942g
uniprot id: B5RTN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2F05764g
gene id: 284592:DEHA2F05764g
uniprot id: Q6BMF9
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

284592:DEHA2G17996g
gene id: 284592:DEHA2G17996g
uniprot id: Q6BHJ9
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2E06006g
gene id: 284592:DEHA2E06006g
uniprot id: B5RTW3
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F02178g
gene id: 284592:DEHA2F02178g
uniprot id: Q6BMW1
names: Similarity
messages: Belongs to the HUS1 family.

284592:DEHA2F19910g
gene id: 284592:DEHA2F19910g
uniprot id: Q6BKR0
names: Function
names: Similarity
messages: Belongs to the flavokinase family.
messages: Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.

284592:DEHA2A12584g
gene id: 284592:DEHA2A12584g
uniprot id: Q6BY42
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

284592:DEHA2C08558g
gene id: 284592:DEHA2C08558g
uniprot id: Q6BUR9
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

284592:DEHA2C09834g
gene id: 284592:DEHA2C09834g
uniprot id: Q6BUK8
names: Similarity
messages: Belongs to the IUNH family.

284592:DEHA2E02948g
gene id: 284592:DEHA2E02948g
uniprot id: Q6BQR3
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G25014g
gene id: 284592:DEHA2G25014g
uniprot id: Q6BGN8
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284592:DEHA2C05170g
gene id: 284592:DEHA2C05170g
uniprot id: Q6BV58
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284592:DEHA2B10340g
gene id: 284592:DEHA2B10340g
uniprot id: Q6BWL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRE9/KNH1 family.
messages: Involved in cell wall beta(1->6) glucan synthesis.
messages: cell wall

284592:DEHA2F15972g
gene id: 284592:DEHA2F15972g
uniprot id: Q6BL68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YAE1 family.
messages: Cytoplasm
messages: May form a complex with LTO1.
messages: Nucleus
messages: The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery. May be required for biogenesis of the large ribosomal subunit and initiation of translation.

284592:DEHA2C16456g
gene id: 284592:DEHA2C16456g
uniprot id: Q6BTR6
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

284592:DEHA2A00902g
gene id: 284592:DEHA2A00902g
uniprot id: Q6BZJ2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

284592:DEHA2F22000g
gene id: 284592:DEHA2F22000g
uniprot id: B5RUL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIT family.
messages: Cytoplasm

284592:DEHA2E22022g
gene id: 284592:DEHA2E22022g
uniprot id: B5RU54
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2G06050g
gene id: 284592:DEHA2G06050g
uniprot id: B5RV40
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.

284592:DEHA2D06600g
gene id: 284592:DEHA2D06600g
uniprot id: Q6BSS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity).
messages: nucleolus

284592:DEHA2A12914g
gene id: 284592:DEHA2A12914g
uniprot id: Q6BY29
names: Similarity
messages: Belongs to the RNase PH family.

284592:DEHA2B13728g
gene id: 284592:DEHA2B13728g
uniprot id: Q6BW76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

284592:DEHA2E12276g
gene id: 284592:DEHA2E12276g
uniprot id: Q6BPN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer.

284592:DEHA2E24178g
gene id: 284592:DEHA2E24178g
uniprot id: Q6BN69
names: Similarity
messages: Belongs to the FMO family.

284592:DEHA2F16478g
gene id: 284592:DEHA2F16478g
uniprot id: B5RUI0
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D18282g
gene id: 284592:DEHA2D18282g
uniprot id: Q6BR90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity).
messages: Component of the heptameric LSM1-LSM7 complex, which consists of LSM1, LSM2, LSM3, LSM4, LSM5, LSM6 and LSM7. Component of the heptameric LSM2-LSM8 complex, which consists of LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. The LSm subunits form a seven-membered ring structure with a doughnut shape (By similarity).
messages: Cytoplasm
messages: Nucleus

284592:DEHA2B13992g
gene id: 284592:DEHA2B13992g
uniprot id: Q6BW64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKN1/KRE6 family.
messages: Membrane

284592:DEHA2A08052g
gene id: 284592:DEHA2A08052g
uniprot id: Q6BYN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

284592:DEHA2G19580g
gene id: 284592:DEHA2G19580g
uniprot id: B5RUV8
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D09658g
gene id: 284592:DEHA2D09658g
uniprot id: Q6BSD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROT1 family.
messages: Endoplasmic reticulum membrane
messages: Required for normal levels of the cell wall 1,6-beta-glucan. Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies (By similarity).

284592:DEHA2A03388g
gene id: 284592:DEHA2A03388g
uniprot id: Q6BZ78
names: Activity Regulation
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Cytoplasm
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

284592:DEHA2E05698g
gene id: 284592:DEHA2E05698g
uniprot id: Q6BQF0
names: Similarity
messages: Belongs to the OPA3 family.

284592:DEHA2B11506g
gene id: 284592:DEHA2B11506g
uniprot id: Q6BWG6
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D15664g
gene id: 284592:DEHA2D15664g
uniprot id: Q6BRK5
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

284592:DEHA2G07392g
gene id: 284592:DEHA2G07392g
uniprot id: Q6BIV2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

284592:DEHA2F23672g
gene id: 284592:DEHA2F23672g
uniprot id: Q6BK99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Component of the 20S proteasome chaperone.
messages: Involved in 20S proteasome assembly.

284592:DEHA2A13992g
gene id: 284592:DEHA2A13992g
uniprot id: Q6BXY1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

284592:DEHA2B08206g
gene id: 284592:DEHA2B08206g
uniprot id: Q6BWV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2C12892g
gene id: 284592:DEHA2C12892g
uniprot id: Q6BU83
names: Function
names: Similarity
messages: Belongs to the CCM1 family.
messages: RNA-binding protein involved in the specific removal of group I introns in mitochondrial encoded transcripts. Maintains the stability of the small subunit mitochondrial 15S rRNA and thus the expression of the mitochondrial genome.

284592:DEHA2C05280g
gene id: 284592:DEHA2C05280g
uniprot id: Q6BV53
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2D14608g
gene id: 284592:DEHA2D14608g
uniprot id: Q6BRQ5
names: Similarity
messages: Belongs to the ZPR1 family.

284592:DEHA2F07304g
gene id: 284592:DEHA2F07304g
uniprot id: Q6BM96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2F17732g
gene id: 284592:DEHA2F17732g
uniprot id: Q6BKZ0
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2A13706g
gene id: 284592:DEHA2A13706g
uniprot id: Q6BXZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

284592:DEHA2G06776g
gene id: 284592:DEHA2G06776g
uniprot id: Q6BIX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

284592:DEHA2E21208g
gene id: 284592:DEHA2E21208g
uniprot id: Q6BNJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAR5 family.
messages: Endoplasmic reticulum membrane
messages: Nucleus membrane
messages: Required for nuclear membrane fusion during karyogamy.

284592:DEHA2D11000g
gene id: 284592:DEHA2D11000g
uniprot id: Q6BS77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

284592:DEHA2B04950g
gene id: 284592:DEHA2B04950g
uniprot id: Q6BX92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASP family.
messages: Golgi apparatus membrane
messages: Membrane

284592:DEHA2B07304g
gene id: 284592:DEHA2B07304g
uniprot id: Q6BWZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

284592:DEHA2E08140g
gene id: 284592:DEHA2E08140g
uniprot id: W0TYS3
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

284592:DEHA2D10274g
gene id: 284592:DEHA2D10274g
uniprot id: Q6BSA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

284592:DEHA2D14982g
gene id: 284592:DEHA2D14982g
uniprot id: Q6BRN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dUTPase family.
messages: Homotrimer.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

284592:DEHA2B15136g
gene id: 284592:DEHA2B15136g
uniprot id: B5RSW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Nucleus

284592:DEHA2F24420g
gene id: 284592:DEHA2F24420g
uniprot id: B5RUN1
names: Similarity
messages: Belongs to the lysophospholipase family.

284592:DEHA2D09570g
gene id: 284592:DEHA2D09570g
uniprot id: Q6BSD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LOT5 family.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2B11242g
gene id: 284592:DEHA2B11242g
uniprot id: Q6BWH9
names: Similarity
messages: Belongs to the SURF6 family.

284592:DEHA2E14498g
gene id: 284592:DEHA2E14498g
uniprot id: Q6BPD4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

284592:DEHA2A10802g
gene id: 284592:DEHA2A10802g
uniprot id: Q6BYB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2G05984g
gene id: 284592:DEHA2G05984g
uniprot id: Q6BJ14
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

284592:DEHA2G23760g
gene id: 284592:DEHA2G23760g
uniprot id: Q6BGU9
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

284592:DEHA2D03630g
gene id: 284592:DEHA2D03630g
uniprot id: Q6BT45
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Homotetramer.

284592:DEHA2F12650g
gene id: 284592:DEHA2F12650g
uniprot id: Q6BLK9
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E07568g
gene id: 284592:DEHA2E07568g
uniprot id: B5RTX0
names: Cofactor
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.

284592:DEHA2G08470g
gene id: 284592:DEHA2G08470g
uniprot id: Q6BIQ6
names: Similarity
messages: Belongs to the lysophospholipase family.

284592:DEHA2F21560g
gene id: 284592:DEHA2F21560g
uniprot id: B5RUL4
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

284592:DEHA2G08888g
gene id: 284592:DEHA2G08888g
uniprot id: B5RV55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Membrane

284592:DEHA2F25102g
gene id: 284592:DEHA2F25102g
uniprot id: Q6BK40
names: Similarity
messages: Belongs to the Rab GDI family.

284592:DEHA2D00924g
gene id: 284592:DEHA2D00924g
uniprot id: Q6BTF9
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

284592:DEHA2C11044g
gene id: 284592:DEHA2C11044g
uniprot id: Q6BUF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

284592:DEHA2B03432g
gene id: 284592:DEHA2B03432g
uniprot id: B5RT45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Regulates the cell cycle in a nutrient dependent manner.

284592:DEHA2B15400g
gene id: 284592:DEHA2B15400g
uniprot id: Q6BW00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: Nucleus
messages: Required for pre-mRNA splicing.

284592:DEHA2F11066g
gene id: 284592:DEHA2F11066g
uniprot id: Q6BLS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. The complex is held together by ERB1, which interacts with NOP7 via its N-terminal domain and with YTM1 via a high-affinity interaction between the seven-bladed beta-propeller domains of the 2 proteins. The NOP7 complex associates with the 66S pre-ribosome. Interacts (via UBL domain) with MDN1 (via VWFA/MIDAS domain).
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

284592:DEHA2A01254g
gene id: 284592:DEHA2A01254g
uniprot id: Q6BZH6
names: Similarity
messages: Belongs to the VPS54 family.

284592:DEHA2G03938g
gene id: 284592:DEHA2G03938g
uniprot id: Q6BJA4
names: Similarity
messages: Belongs to the UFD1 family.

284592:DEHA2G20922g
gene id: 284592:DEHA2G20922g
uniprot id: Q6BH69
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

284592:DEHA2B08074g
gene id: 284592:DEHA2B08074g
uniprot id: Q6BWW2
names: Similarity
messages: Belongs to the SRR1 family.

284592:DEHA2G23056g
gene id: 284592:DEHA2G23056g
uniprot id: Q6BGX6
names: Similarity
messages: Belongs to the MTFP1 family.

284592:DEHA2D07282g
gene id: 284592:DEHA2D07282g
uniprot id: Q6BSP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2F04510g
gene id: 284592:DEHA2F04510g
uniprot id: Q6BMK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AEP2 family.
messages: Binds to the 5'UTR of the OLI1 mRNA.
messages: Mitochondrion
messages: Required for translation of the mitochondrial OLI1 transcript coding for the mitochondrial ATP synthase subunit 9.

284592:DEHA2G03608g
gene id: 284592:DEHA2G03608g
uniprot id: Q6BJB9
names: Similarity
messages: Belongs to the complex I LYR family.

284592:DEHA2E09966g
gene id: 284592:DEHA2E09966g
uniprot id: Q6BPY0
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

284592:DEHA2E22572g
gene id: 284592:DEHA2E22572g
uniprot id: Q6BND8
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.

284592:DEHA2B06644g
gene id: 284592:DEHA2B06644g
uniprot id: Q6BX21
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F05918g
gene id: 284592:DEHA2F05918g
uniprot id: Q6BMF3
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

284592:DEHA2F09174g
gene id: 284592:DEHA2F09174g
uniprot id: Q6BM11
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

284592:DEHA2A09196g
gene id: 284592:DEHA2A09196g
uniprot id: Q6BYJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MET18/MMS19 family.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus

284592:DEHA2C15664g
gene id: 284592:DEHA2C15664g
uniprot id: Q6BTV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIL1 family.
messages: Endoplasmic reticulum lumen
messages: Interacts with KAR2.
messages: Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone KAR2 (By similarity).

284592:DEHA2G21714g
gene id: 284592:DEHA2G21714g
uniprot id: Q6BH34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with nucleolar and cytoplasmic pre-60S particles. At the end of biogenesis it dissociates from cytoplasmic pre-60S particles and is likely to be exchanged for its ribosomal homolog, RPL24.
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Cytoplasm
messages: Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of DEHA2D15950g/NOG1 to pre-60S particles. Activates and recruits ATPase AFG2 to cytoplasmic pre-60S ribosomal particles.
messages: Nucleus

284592:DEHA2G15400g
gene id: 284592:DEHA2G15400g
uniprot id: Q6BHV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminopeptidase that preferentially cleaves di- and tripeptides. Also has low epoxide hydrolase activity (in vitro). Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2F06314g
gene id: 284592:DEHA2F06314g
uniprot id: W0TYT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

284592:DEHA2A10032g
gene id: 284592:DEHA2A10032g
uniprot id: Q6BYF2
names: Similarity
messages: Belongs to the peptidase C19 family.

284592:DEHA2G09152g
gene id: 284592:DEHA2G09152g
uniprot id: Q6BIM6
names: Function
names: Similarity
messages: Belongs to the PanB family.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.

284592:DEHA2G05324g
gene id: 284592:DEHA2G05324g
uniprot id: Q6BJ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284592:DEHA2E19118g
gene id: 284592:DEHA2E19118g
uniprot id: Q6BNT5
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2F15664g
gene id: 284592:DEHA2F15664g
uniprot id: B5RUH4
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

284592:DEHA2F13288g
gene id: 284592:DEHA2F13288g
uniprot id: Q6BLI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

284592:DEHA2F25498g
gene id: 284592:DEHA2F25498g
uniprot id: B5RUN7
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C06446g
gene id: 284592:DEHA2C06446g
uniprot id: Q6BV03
names: Similarity
messages: Belongs to the UPF0538 family.

284592:DEHA2B01694g
gene id: 284592:DEHA2B01694g
uniprot id: Q6BXN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP4 subfamily.
messages: Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (By similarity).
messages: Component of the NuA4 histone acetyltransferase complex, of the INO80 chromatin remodeling complex, and of the SWR1 chromatin remodeling complex.
messages: Nucleus

284592:DEHA2C09108g
gene id: 284592:DEHA2C09108g
uniprot id: Q6BUP6
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E18502g
gene id: 284592:DEHA2E18502g
uniprot id: Q6BNW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).

284592:DEHA2D03454g
gene id: 284592:DEHA2D03454g
uniprot id: B5RTQ7
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2E23936g
gene id: 284592:DEHA2E23936g
uniprot id: Q6BN79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Membrane

284592:DEHA2C13772g
gene id: 284592:DEHA2C13772g
uniprot id: Q6BU42
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer; composed of 3 copies of TIM9 and 3 copies of TIM10, named soluble 70 kDa complex. Associates with the TIM22 complex, whose core is composed of TIM22 and TIM54. Interacts with the transmembrane regions of multi-pass transmembrane proteins in transit (By similarity).
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. However, during the transit of TIM9 from cytoplasm into mitochondrion, the Cys residues probably coordinate zinc, thereby preventing folding and allowing its transfer across mitochondrial outer membrane (By similarity).

284592:DEHA2C06248g
gene id: 284592:DEHA2C06248g
uniprot id: Q6BV10
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E17578g
gene id: 284592:DEHA2E17578g
uniprot id: Q6BP06
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D15356g
gene id: 284592:DEHA2D15356g
uniprot id: Q6BRM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Endomembrane system
messages: Vacuole membrane

284592:DEHA2G17358g
gene id: 284592:DEHA2G17358g
uniprot id: Q6BHM7
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

284592:DEHA2B15224g
gene id: 284592:DEHA2B15224g
uniprot id: Q6BW08
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

284592:DEHA2E16038g
gene id: 284592:DEHA2E16038g
uniprot id: Q6BP70
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX4 family.
messages: Forms a heterodimer with SLX1.
messages: Nucleus
messages: Phosphorylated in response to DNA damage.
messages: Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.

284592:DEHA2G17138g
gene id: 284592:DEHA2G17138g
uniprot id: Q6BHN7
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

284592:DEHA2E21912g
gene id: 284592:DEHA2E21912g
uniprot id: Q6BNG6
names: Similarity
messages: Belongs to the PP2C family.

284592:DEHA2F16016g
gene id: 284592:DEHA2F16016g
uniprot id: Q6BL66
names: Similarity
messages: Belongs to the activator 1 small subunits family.

284592:DEHA2B03652g
gene id: 284592:DEHA2B03652g
uniprot id: B5RT39
names: Function
names: Similarity
messages: Belongs to the CHZ1 family.
messages: Forms a chaperone-bound H2A.Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A.Z histone replacement in chromatin.

284592:DEHA2G07326g
gene id: 284592:DEHA2G07326g
uniprot id: Q6BIV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Probably involved in transport through the plasma membrane.

284592:DEHA2B03894g
gene id: 284592:DEHA2B03894g
uniprot id: Q6BXD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
messages: Homodimer.
messages: Mitochondrion inner membrane
messages: Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating the ATP-dependent export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins (By similarity). Hydrolyzes ATP (By similarity). Binds glutathione and may function by transporting a glutathione-conjugated iron-sulfur compound (By similarity).

284592:DEHA2D10406g
gene id: 284592:DEHA2D10406g
uniprot id: Q6BSA2
names: Similarity
messages: Belongs to the heat shock protein 90 family.

284592:DEHA2F13794g
gene id: 284592:DEHA2F13794g
uniprot id: Q6BLF8
names: Similarity
messages: Belongs to the TEL2 family.

284592:DEHA2D06160g
gene id: 284592:DEHA2D06160g
uniprot id: Q6BSU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

284592:DEHA2C03146g
gene id: 284592:DEHA2C03146g
uniprot id: B5RT68
names: Similarity
messages: Belongs to the SH3BGR family.

284592:DEHA2B02486g
gene id: 284592:DEHA2B02486g
uniprot id: Q6BXJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

284592:DEHA2C13442g
gene id: 284592:DEHA2C13442g
uniprot id: Q6BU56
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

284592:DEHA2B10538g
gene id: 284592:DEHA2B10538g
uniprot id: Q6BWK8
names: Subcellular Location Annotation
messages: nucleolus

284592:DEHA2F02222g
gene id: 284592:DEHA2F02222g
uniprot id: Q6BMV8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

284592:DEHA2G23430g
gene id: 284592:DEHA2G23430g
uniprot id: Q6BGW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2H phosphoesterase superfamily. CPD1 family.
messages: Golgi apparatus
messages: Involved in the metabolism of ADP-ribose 1',2'-cyclic phosphate which is produced as a consequence of tRNA splicing.

284592:DEHA2D15708g
gene id: 284592:DEHA2D15708g
uniprot id: Q6BRK3
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

284592:DEHA2G17248g
gene id: 284592:DEHA2G17248g
uniprot id: Q6BHN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

284592:DEHA2C13904g
gene id: 284592:DEHA2C13904g
uniprot id: Q6BU36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin-conjugating enzyme family.
messages: Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2A01936g
gene id: 284592:DEHA2A01936g
uniprot id: Q6BZE7
names: Similarity
messages: Belongs to the proteasome subunit S11 family.

284592:DEHA2F23254g
gene id: 284592:DEHA2F23254g
uniprot id: Q6BKB9
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.

284592:DEHA2D07392g
gene id: 284592:DEHA2D07392g
uniprot id: Q6BSN8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

284592:DEHA2G15642g
gene id: 284592:DEHA2G15642g
uniprot id: B5RUT7
names: Similarity
messages: Belongs to the glutamate synthase family.

284592:DEHA2G11220g
gene id: 284592:DEHA2G11220g
uniprot id: B5RUQ5
names: Similarity
messages: Belongs to the SLA2 family.

284592:DEHA2C01386g
gene id: 284592:DEHA2C01386g
uniprot id: Q6BVM7
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-67 and Arg-70) that bind to malonylated and succinylated substrates and define the specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.

284592:DEHA2C13596g
gene id: 284592:DEHA2C13596g
uniprot id: Q6BU50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

284592:DEHA2D18590g
gene id: 284592:DEHA2D18590g
uniprot id: Q6BR77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with DRE2; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Mitochondrion
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. Positively controls H(2)O(2)-induced cell death.

284592:DEHA2D04092g
gene id: 284592:DEHA2D04092g
uniprot id: Q6BT25
names: Similarity
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.

284592:DEHA2C10054g
gene id: 284592:DEHA2C10054g
uniprot id: Q6BUJ8
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.

284592:DEHA2A10230g
gene id: 284592:DEHA2A10230g
uniprot id: Q6BYE3
names: Similarity
messages: Belongs to the RICTOR family.

284592:DEHA2D02200g
gene id: 284592:DEHA2D02200g
uniprot id: Q6BTA7
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E07238g
gene id: 284592:DEHA2E07238g
uniprot id: B5RTW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

284592:DEHA2C16808g
gene id: 284592:DEHA2C16808g
uniprot id: B5RTC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284592:DEHA2F13860g
gene id: 284592:DEHA2F13860g
uniprot id: Q6BLF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

284592:DEHA2A10582g
gene id: 284592:DEHA2A10582g
uniprot id: Q6BYC6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

284592:DEHA2D05654g
gene id: 284592:DEHA2D05654g
uniprot id: B5RTR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

284592:DEHA2G15510g
gene id: 284592:DEHA2G15510g
uniprot id: Q6BHV4
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F11176g
gene id: 284592:DEHA2F11176g
uniprot id: Q6BLS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Cytoplasm
messages: Mevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway. The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.

284592:DEHA2A09900g
gene id: 284592:DEHA2A09900g
uniprot id: Q6BYF7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

284592:DEHA2A04686g
gene id: 284592:DEHA2A04686g
uniprot id: Q6BZ44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation (By similarity).

284592:DEHA2G07304g
gene id: 284592:DEHA2G07304g
uniprot id: B5RV46
names: Similarity
messages: Belongs to the VPS29 family.

284592:DEHA2F00946g
gene id: 284592:DEHA2F00946g
uniprot id: Q6BN18
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2B09592g
gene id: 284592:DEHA2B09592g
uniprot id: Q6BWP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism.

284592:DEHA2E19690g
gene id: 284592:DEHA2E19690g
uniprot id: Q6BNQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Component of the nucleolar and nucleoplasmic pre-60S ribosomal particle.
messages: Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

284592:DEHA2E11308g
gene id: 284592:DEHA2E11308g
uniprot id: Q6BPS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

284592:DEHA2G02486g
gene id: 284592:DEHA2G02486g
uniprot id: Q6BJG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.

284592:DEHA2F26004g
gene id: 284592:DEHA2F26004g
uniprot id: Q6BK01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.

284592:DEHA2C02860g
gene id: 284592:DEHA2C02860g
uniprot id: Q6BVG5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2C04950g
gene id: 284592:DEHA2C04950g
uniprot id: Q6BV67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

284592:DEHA2F24398g
gene id: 284592:DEHA2F24398g
uniprot id: Q6BK70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
messages: Cytoplasm

284592:DEHA2G21186g
gene id: 284592:DEHA2G21186g
uniprot id: Q6BH57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

284592:DEHA2F04972g
gene id: 284592:DEHA2F04972g
uniprot id: B5RU98
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

284592:DEHA2E13992g
gene id: 284592:DEHA2E13992g
uniprot id: Q6BPF6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.

284592:DEHA2B09416g
gene id: 284592:DEHA2B09416g
uniprot id: Q6BWQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NBP35 and two labile, bridging clusters between subunits of the NBP35-CFD1 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export.
messages: Cytoplasm
messages: Heterotetramer of 2 NBP35 and 2 CFD1 chains.

284592:DEHA2F06094g
gene id: 284592:DEHA2F06094g
uniprot id: Q6BME7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

284592:DEHA2D11990g
gene id: 284592:DEHA2D11990g
uniprot id: Q6BS30
names: Similarity
messages: Belongs to the UQCRH/QCR6 family.

284592:DEHA2C04884g
gene id: 284592:DEHA2C04884g
uniprot id: Q6BV70
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

284592:DEHA2B10252g
gene id: 284592:DEHA2B10252g
uniprot id: B5RT08
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

284592:DEHA2F22022g
gene id: 284592:DEHA2F22022g
uniprot id: B5RUL6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM12 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane
messages: The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.

284592:DEHA2C15136g
gene id: 284592:DEHA2C15136g
uniprot id: Q6BTX7
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2B04136g
gene id: 284592:DEHA2B04136g
uniprot id: Q6BXC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLPL family.
messages: Membrane
messages: Probable lipid hydrolase.

284592:DEHA2E10604g
gene id: 284592:DEHA2E10604g
uniprot id: Q6BPV2
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

284592:DEHA2F19228g
gene id: 284592:DEHA2F19228g
uniprot id: Q6BKU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

284592:DEHA2A02992g
gene id: 284592:DEHA2A02992g
uniprot id: Q6BZ96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

284592:DEHA2D12056g
gene id: 284592:DEHA2D12056g
uniprot id: Q6BS27
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D04202g
gene id: 284592:DEHA2D04202g
uniprot id: Q6BT20
names: Similarity
messages: Belongs to the SecY/SEC61-alpha family.

284592:DEHA2G21648g
gene id: 284592:DEHA2G21648g
uniprot id: Q6BH37
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM14 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1) (By similarity).
messages: Heterodimer with PAM16. Component of the PAM complex, at least composed of mtHsp70, MGE1, TIM44, PAM16, PAM17 and PAM18 (By similarity).
messages: Mitochondrion inner membrane
messages: The J domain is essential for co-chaperone activity and mediates the heterodimerization with the J-like domain of PAM16.

284592:DEHA2D03234g
gene id: 284592:DEHA2D03234g
uniprot id: Q6BT62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

284592:DEHA2A14410g
gene id: 284592:DEHA2A14410g
uniprot id: Q6BXW3
names: Similarity
messages: Belongs to the FMO family.

284592:DEHA2C03410g
gene id: 284592:DEHA2C03410g
uniprot id: Q6BVD8
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C16852g
gene id: 284592:DEHA2C16852g
uniprot id: Q6BTP8
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

284592:DEHA2A04818g
gene id: 284592:DEHA2A04818g
uniprot id: Q6BZ38
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

284592:DEHA2F11660g
gene id: 284592:DEHA2F11660g
uniprot id: Q6BLQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

284592:DEHA2F02662g
gene id: 284592:DEHA2F02662g
uniprot id: Q6BMT8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

284592:DEHA2A11550g
gene id: 284592:DEHA2A11550g
uniprot id: Q6BY84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

284592:DEHA2G14080g
gene id: 284592:DEHA2G14080g
uniprot id: Q6BI19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.

284592:DEHA2C01342g
gene id: 284592:DEHA2C01342g
uniprot id: Q6BVM9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

284592:DEHA2F26532g
gene id: 284592:DEHA2F26532g
uniprot id: W0TYU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TPT transporter family. SLC35D subfamily.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homooligomer.
messages: Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
messages: Membrane

284592:DEHA2G00638g
gene id: 284592:DEHA2G00638g
uniprot id: Q6BJR0
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F24068g
gene id: 284592:DEHA2F24068g
uniprot id: Q6BK83
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2C02288g
gene id: 284592:DEHA2C02288g
uniprot id: Q6BVI9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion

284592:DEHA2A01364g
gene id: 284592:DEHA2A01364g
uniprot id: Q6BZH1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Endoplasmic reticulum lumen
messages: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.
messages: The chaperone activity is regulated by ATP-induced allosteric coupling of the nucleotide-binding (NBD) and substrate-binding (SBD) domains. In the ADP-bound and nucleotide-free (apo) states, the two domains have little interaction. In contrast, in the ATP-bound state the two domains are tightly coupled, which results in drastically accelerated kinetics in both binding and release of polypeptide substrates. J domain-containing co-chaperones stimulate the ATPase activity and are required for efficient substrate recognition.

284592:DEHA2F03740g
gene id: 284592:DEHA2F03740g
uniprot id: Q6BMP2
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

284592:DEHA2G11814g
gene id: 284592:DEHA2G11814g
uniprot id: Q6BIC9
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

284592:DEHA2F00264g
gene id: 284592:DEHA2F00264g
uniprot id: Q6BN48
names: Subcellular Location Annotation
messages: telomere

284592:DEHA2D07832g
gene id: 284592:DEHA2D07832g
uniprot id: Q6BSM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors GET1 and GET2, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the GET1-GET2 receptor, and returning it to the cytosol to initiate a new round of targeting. Cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER. Involved in low-level resistance to the oxyanions arsenite and arsenate, and in heat tolerance.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer. Interacts with the chloride channel protein GEF1.

284592:DEHA2C12166g
gene id: 284592:DEHA2C12166g
uniprot id: Q6BUB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

284592:DEHA2B15158g
gene id: 284592:DEHA2B15158g
uniprot id: Q6BW11
names: Similarity
messages: Belongs to the RNR ribonuclease family.

284592:DEHA2D10978g
gene id: 284592:DEHA2D10978g
uniprot id: Q6BS78
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

284592:DEHA2F22176g
gene id: 284592:DEHA2F22176g
uniprot id: Q6BKG4
names: Similarity
messages: Belongs to the RRP12 family.

284592:DEHA2D11110g
gene id: 284592:DEHA2D11110g
uniprot id: Q6BS72
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

284592:DEHA2D08910g
gene id: 284592:DEHA2D08910g
uniprot id: Q6BSG9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

284592:DEHA2E03190g
gene id: 284592:DEHA2E03190g
uniprot id: Q6BQQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

284592:DEHA2A13926g
gene id: 284592:DEHA2A13926g
uniprot id: Q6BXY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

284592:DEHA2F12364g
gene id: 284592:DEHA2F12364g
uniprot id: Q6BLM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Binds to both phosphatidylinositol (PI) and phosphatidylinositol 3,5-bisphosphate (PIP2).
messages: Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by ATG15 is critical to life span extension (By similarity).
messages: Prevacuolar compartment membrane
messages: multivesicular body membrane

284592:DEHA2B14850g
gene id: 284592:DEHA2B14850g
uniprot id: Q6BW26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPC1 family.
messages: Membrane

284592:DEHA2C14256g
gene id: 284592:DEHA2C14256g
uniprot id: Q6BU18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC26 family.
messages: Cytoplasm
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284592:DEHA2D04730g
gene id: 284592:DEHA2D04730g
uniprot id: Q6BSZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YPI1 family.
messages: Nucleus
messages: Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.

284592:DEHA2F08514g
gene id: 284592:DEHA2F08514g
uniprot id: Q6BM39
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
messages: Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.

284592:DEHA2E20086g
gene id: 284592:DEHA2E20086g
uniprot id: Q6BNP1
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

284592:DEHA2E19976g
gene id: 284592:DEHA2E19976g
uniprot id: Q6BNP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the STAM family.
messages: Component of the ESCRT-0 complex composed of HSE1 and VPS27.
messages: Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).
messages: Endosome membrane

284592:DEHA2G19096g
gene id: 284592:DEHA2G19096g
uniprot id: Q6BHF1
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

284592:DEHA2E17358g
gene id: 284592:DEHA2E17358g
uniprot id: Q6BP14
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284592:DEHA2F18282g
gene id: 284592:DEHA2F18282g
uniprot id: Q6BKW8
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated by ESA1 to form H2AK4ac and H2AK7ac.
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: In contrast to vertebrates and insects, its C-terminus is not monoubiquitinated.
messages: Nucleus
messages: Phosphorylated to form H2AS128ph (gamma-H2A) in response to DNA double-strand breaks (DSBs) generated by exogenous genotoxic agents and by stalled replication forks. Phosphorylation is dependent on the DNA damage checkpoint kinases MEC1/ATR and TEL1/ATM, spreads on either side of a detected DSB site and may mark the surrounding chromatin for recruitment of proteins required for DNA damage signaling and repair. Gamma-H2A is removed from the DNA prior to the strand invasion-primer extension step of the repair process and subsequently dephosphorylated. Dephosphorylation is necessary for efficient recovery from the DNA damage checkpoint (By similarity).
messages: The [ST]-Q motif constitutes a recognition sequence for kinases from the PI3/PI4-kinase family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H2AK4ac = acetylated Lys-5; H2AK7ac = acetylated Lys-7; H2AS128ph = phosphorylated Ser-127.

284592:DEHA2C10362g
gene id: 284592:DEHA2C10362g
uniprot id: Q6BUI6
names: Subcellular Location Annotation
messages: telomere

284592:DEHA2F05632g
gene id: 284592:DEHA2F05632g
uniprot id: Q6BMG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

284592:DEHA2D09460g
gene id: 284592:DEHA2D09460g
uniprot id: Q6BSE4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).
messages: Cytoplasm

284592:DEHA2C06974g
gene id: 284592:DEHA2C06974g
uniprot id: Q6BUY4
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.

284592:DEHA2D11308g
gene id: 284592:DEHA2D11308g
uniprot id: Q6BS63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

284592:DEHA2E19360g
gene id: 284592:DEHA2E19360g
uniprot id: Q6BNS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

284592:DEHA2E10538g
gene id: 284592:DEHA2E10538g
uniprot id: Q6BPV5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

284592:DEHA2F02970g
gene id: 284592:DEHA2F02970g
uniprot id: Q6BMS6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

284592:DEHA2E01694g
gene id: 284592:DEHA2E01694g
uniprot id: Q6BQW6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

284592:DEHA2F23364g
gene id: 284592:DEHA2F23364g
uniprot id: B5RUM3
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C01452g
gene id: 284592:DEHA2C01452g
uniprot id: Q6BVM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BOS1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: SNARE required for protein transport between the ER and the Golgi complex.

284592:DEHA2B12958g
gene id: 284592:DEHA2B12958g
uniprot id: Q6BWB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2D05324g
gene id: 284592:DEHA2D05324g
uniprot id: Q6BSX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

284592:DEHA2C15972g
gene id: 284592:DEHA2C15972g
uniprot id: Q6BTT8
names: Similarity
messages: Belongs to the protein kinase superfamily.

284592:DEHA2G21230g
gene id: 284592:DEHA2G21230g
uniprot id: Q6BH55
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

284592:DEHA2G14762g
gene id: 284592:DEHA2G14762g
uniprot id: Q6BHY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

284592:DEHA2G19888g
gene id: 284592:DEHA2G19888g
uniprot id: Q6BHB3
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2G24398g
gene id: 284592:DEHA2G24398g
uniprot id: Q6BGR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus
messages: Pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase.

284592:DEHA2B13398g
gene id: 284592:DEHA2B13398g
uniprot id: Q6BW91
names: Similarity
messages: Belongs to the TRM112 family.

284592:DEHA2A02772g
gene id: 284592:DEHA2A02772g
uniprot id: B5RSP6
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E09944g
gene id: 284592:DEHA2E09944g
uniprot id: Q6BPY1
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C15466g
gene id: 284592:DEHA2C15466g
uniprot id: Q6BTW2
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C05258g
gene id: 284592:DEHA2C05258g
uniprot id: Q6BV54
names: Similarity
messages: Belongs to the phosphohexose mutase family.

284592:DEHA2F27126g
gene id: 284592:DEHA2F27126g
uniprot id: Q6BJV3
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284592:DEHA2D10164g
gene id: 284592:DEHA2D10164g
uniprot id: Q6BSB3
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F20504g
gene id: 284592:DEHA2F20504g
uniprot id: Q6BKN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTU2/NCS2 family.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

284592:DEHA2E16764g
gene id: 284592:DEHA2E16764g
uniprot id: Q6BP39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

284592:DEHA2A10824g
gene id: 284592:DEHA2A10824g
uniprot id: Q6BYB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2F20790g
gene id: 284592:DEHA2F20790g
uniprot id: Q6BKL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

284592:DEHA2C02508g
gene id: 284592:DEHA2C02508g
uniprot id: Q6BVI0
names: Similarity
messages: Belongs to the protein kinase superfamily.

284592:DEHA2G14608g
gene id: 284592:DEHA2G14608g
uniprot id: B5RUT0
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E03784g
gene id: 284592:DEHA2E03784g
uniprot id: Q6BQN1
names: Cofactor
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Reduced FMN (FMNH(2)).

284592:DEHA2B08866g
gene id: 284592:DEHA2B08866g
uniprot id: Q6BWS8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the calcineurin regulatory subunit family.
messages: Composed of a catalytic subunit (A) and a regulatory subunit (B).
messages: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity (By similarity).
messages: This protein has four functional calcium-binding sites.

284592:DEHA2F12122g
gene id: 284592:DEHA2F12122g
uniprot id: Q6BLN0
names: Similarity
messages: Belongs to the VPS72/YL1 family.

284592:DEHA2A10516g
gene id: 284592:DEHA2A10516g
uniprot id: Q6BRZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

284592:DEHA2F01474g
gene id: 284592:DEHA2F01474g
uniprot id: Q6BMZ3
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2F17776g
gene id: 284592:DEHA2F17776g
uniprot id: Q6BKY8
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

284592:DEHA2F07348g
gene id: 284592:DEHA2F07348g
uniprot id: Q6BM94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

284592:DEHA2A13376g
gene id: 284592:DEHA2A13376g
uniprot id: Q6BY08
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

284592:DEHA2D10560g
gene id: 284592:DEHA2D10560g
uniprot id: Q6BS95
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

284592:DEHA2E22396g
gene id: 284592:DEHA2E22396g
uniprot id: Q6BNE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

284592:DEHA2G02376g
gene id: 284592:DEHA2G02376g
uniprot id: Q6BJH5
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.
messages: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.

284592:DEHA2G24750g
gene id: 284592:DEHA2G24750g
uniprot id: B5RV04
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

284592:DEHA2C10934g
gene id: 284592:DEHA2C10934g
uniprot id: Q6BUG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

284592:DEHA2G20086g
gene id: 284592:DEHA2G20086g
uniprot id: Q6BHA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SPT4 family.
messages: Component of the SPT4-SPT5 complex. Interacts with RNA polymerase II (By similarity).
messages: Nucleus
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).
messages: centromere

284592:DEHA2D10142g
gene id: 284592:DEHA2D10142g
uniprot id: Q6BSB4
names: Similarity
messages: Belongs to the TBCC family.

284592:DEHA2D18634g
gene id: 284592:DEHA2D18634g
uniprot id: Q6BR75
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

284592:DEHA2D08932g
gene id: 284592:DEHA2D08932g
uniprot id: B5RTF7
names: Similarity
messages: Belongs to the APC1 family.

284592:DEHA2C11880g
gene id: 284592:DEHA2C11880g
uniprot id: Q6BUC7
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2C03982g
gene id: 284592:DEHA2C03982g
uniprot id: Q6BVB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly. Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum (By similarity).

284592:DEHA2B09702g
gene id: 284592:DEHA2B09702g
uniprot id: B5RSZ2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

284592:DEHA2B15642g
gene id: 284592:DEHA2B15642g
uniprot id: Q6BVY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21. Interacts with preproteins in transit (By similarity).
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex (By similarity).
messages: Mitochondrion inner membrane

284592:DEHA2B01760g
gene id: 284592:DEHA2B01760g
uniprot id: Q6BXM7
names: Subcellular Location Annotation
messages: nucleolus

284592:DEHA2A01650g
gene id: 284592:DEHA2A01650g
uniprot id: Q6BZF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus

284592:DEHA2D17908g
gene id: 284592:DEHA2D17908g
uniprot id: Q6BRA5
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

284592:DEHA2A12012g
gene id: 284592:DEHA2A12012g
uniprot id: Q6BY67
names: Similarity
messages: Belongs to the VPS26 family.

284592:DEHA2A06006g
gene id: 284592:DEHA2A06006g
uniprot id: Q6BYY5
names: Similarity
messages: Belongs to the WD repeat rae1 family.

284592:DEHA2A03630g
gene id: 284592:DEHA2A03630g
uniprot id: Q6BZ69
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2F10868g
gene id: 284592:DEHA2F10868g
uniprot id: Q6BLT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an inhibitor of cap-dependent translation. Competes with eIF4G1 and EAP1 for binding to eIF4E and interferes with the formation of the eIF4F complex, inhibiting translation and stabilizing mRNA (By similarity).
messages: Belongs to the CAF20 family.
messages: Cytoplasm

284592:DEHA2F17754g
gene id: 284592:DEHA2F17754g
uniprot id: Q6BKY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Forms a one-to-one complex with cytochrome c.
messages: Mitochondrion

284592:DEHA2E12122g
gene id: 284592:DEHA2E12122g
uniprot id: Q6BPN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERF4 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with ERF2.
messages: The ERF2-ERF4 complex is a palmitoyltransferase specific for Ras proteins. Palmitoylates RAS2, which is required for its proper plasma membrane localization (By similarity).

284592:DEHA2D14960g
gene id: 284592:DEHA2D14960g
uniprot id: Q6BRN8
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C17600g
gene id: 284592:DEHA2C17600g
uniprot id: Q6BTL2
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D08162g
gene id: 284592:DEHA2D08162g
uniprot id: Q6BSK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
messages: Belongs to the ATG17 family.
messages: Cytoplasm
messages: Preautophagosomal structure membrane

284592:DEHA2F26862g
gene id: 284592:DEHA2F26862g
uniprot id: Q6BJW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

284592:DEHA2B10032g
gene id: 284592:DEHA2B10032g
uniprot id: Q6BWN1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.

284592:DEHA2C06666g
gene id: 284592:DEHA2C06666g
uniprot id: Q6BUZ4
names: Similarity
messages: Belongs to the protein kinase superfamily.

284592:DEHA2F16434g
gene id: 284592:DEHA2F16434g
uniprot id: Q6BL48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

284592:DEHA2C14388g
gene id: 284592:DEHA2C14388g
uniprot id: Q6BU11
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2G17864g
gene id: 284592:DEHA2G17864g
uniprot id: Q6BHK5
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

284592:DEHA2C12782g
gene id: 284592:DEHA2C12782g
uniprot id: B5RTA8
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C16632g
gene id: 284592:DEHA2C16632g
uniprot id: Q6BTQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

284592:DEHA2G22440g
gene id: 284592:DEHA2G22440g
uniprot id: B5RUX8
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

284592:DEHA2B14608g
gene id: 284592:DEHA2B14608g
uniprot id: Q6BW37
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2B07920g
gene id: 284592:DEHA2B07920g
uniprot id: B5RT10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC4 subfamily.
messages: Nucleus

284592:DEHA2C15620g
gene id: 284592:DEHA2C15620g
uniprot id: Q6BTV7
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

284592:DEHA2E24200g
gene id: 284592:DEHA2E24200g
uniprot id: B5RU68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

284592:DEHA2F21098g
gene id: 284592:DEHA2F21098g
uniprot id: B5RUK6
names: Similarity
messages: Belongs to the CAP family.

284592:DEHA2B01100g
gene id: 284592:DEHA2B01100g
uniprot id: Q6BXQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HEATR1/UTP10 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity).
messages: Membrane
messages: nucleolus

284592:DEHA2B07260g
gene id: 284592:DEHA2B07260g
uniprot id: B5RSX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284592:DEHA2B15510g
gene id: 284592:DEHA2B15510g
uniprot id: Q6BVZ5
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

284592:DEHA2F15070g
gene id: 284592:DEHA2F15070g
uniprot id: Q6BLA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP52 family.
messages: Mitochondrion outer membrane

284592:DEHA2F21340g
gene id: 284592:DEHA2F21340g
uniprot id: B5RUL0
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.

284592:DEHA2C11792g
gene id: 284592:DEHA2C11792g
uniprot id: Q6BUD2
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

284592:DEHA2A01804g
gene id: 284592:DEHA2A01804g
uniprot id: Q6BZF2
names: Similarity
messages: Belongs to the epsin family.

284592:DEHA2E02772g
gene id: 284592:DEHA2E02772g
uniprot id: Q6BQS1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

284592:DEHA2G08602g
gene id: 284592:DEHA2G08602g
uniprot id: Q6BIQ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

284592:DEHA2C15092g
gene id: 284592:DEHA2C15092g
uniprot id: Q6BTX9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM10 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. Associates with the mitochondrial outer membrane sorting assembly machinery SAM(core) complex.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
messages: Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.
messages: Mitochondrion outer membrane

284592:DEHA2F09834g
gene id: 284592:DEHA2F09834g
uniprot id: Q6BLY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

284592:DEHA2F17842g
gene id: 284592:DEHA2F17842g
uniprot id: Q6BKY5
names: Similarity
messages: In the 2nd section; belongs to the type-I 3-dehydroquinase family.
messages: In the N-terminal section; belongs to the shikimate kinase family.

284592:DEHA2E16368g
gene id: 284592:DEHA2E16368g
uniprot id: Q6BP57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

284592:DEHA2F04004g
gene id: 284592:DEHA2F04004g
uniprot id: Q6BMN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.
messages: Belongs to the CNOT2/3/5 family.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2C09064g
gene id: 284592:DEHA2C09064g
uniprot id: Q6BUP8
names: Similarity
messages: Belongs to the PPP phosphatase family.

284592:DEHA2F24156g
gene id: 284592:DEHA2F24156g
uniprot id: Q6BK79
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2A12166g
gene id: 284592:DEHA2A12166g
uniprot id: Q6BY60
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G10846g
gene id: 284592:DEHA2G10846g
uniprot id: Q6BIF7
names: Similarity
messages: Belongs to the MUB1/samB family.

284592:DEHA2G09944g
gene id: 284592:DEHA2G09944g
uniprot id: Q6BIJ2
names: Similarity
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.

284592:DEHA2A07128g
gene id: 284592:DEHA2A07128g
uniprot id: Q6BYT4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

284592:DEHA2F05654g
gene id: 284592:DEHA2F05654g
uniprot id: Q6BMG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG8 family.
messages: Membrane

284592:DEHA2G03850g
gene id: 284592:DEHA2G03850g
uniprot id: Q6BJA8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

284592:DEHA2C01606g
gene id: 284592:DEHA2C01606g
uniprot id: Q6BVL7
names: Similarity
messages: Belongs to the DapA family.

284592:DEHA2G10934g
gene id: 284592:DEHA2G10934g
uniprot id: Q6BIF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2A06556g
gene id: 284592:DEHA2A06556g
uniprot id: B5RSR6
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2G08778g
gene id: 284592:DEHA2G08778g
uniprot id: Q6BIP3
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

284592:DEHA2E04840g
gene id: 284592:DEHA2E04840g
uniprot id: Q6BQJ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking and spindle migration.
messages: The VTT domain was previously called the SNARE-assoc domain. As there is no evidence that this domain associates with SNARE proteins, it was renamed as VMP1, TMEM41, and TVP38 (VTT) domain.

284592:DEHA2D06446g
gene id: 284592:DEHA2D06446g
uniprot id: Q6BST2
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2F20746g
gene id: 284592:DEHA2F20746g
uniprot id: Q6BKM1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

284592:DEHA2F21582g
gene id: 284592:DEHA2F21582g
uniprot id: Q6BKI9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS30 family.

284592:DEHA2A13442g
gene id: 284592:DEHA2A13442g
uniprot id: Q6BY05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Mitochondrion inner membrane
messages: Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.

284592:DEHA2G19646g
gene id: 284592:DEHA2G19646g
uniprot id: Q6BHC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2F06864g
gene id: 284592:DEHA2F06864g
uniprot id: Q6BMB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in mitochondrial genome encoded proteins translation. Involved in the binding of tRNA to the ribosomes (By similarity).
messages: Mitochondrion
messages: Part of the mitochondrial small ribosomal subunit.

284592:DEHA2E15422g
gene id: 284592:DEHA2E15422g
uniprot id: Q6BP94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CGI121/TPRKB family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. CGI121 is not required for tRNA modification (By similarity).
messages: Nucleus
messages: telomere

284592:DEHA2E07810g
gene id: 284592:DEHA2E07810g
uniprot id: Q6BQ71
names: Similarity
messages: Belongs to the WD repeat RAPTOR family.

284592:DEHA2D16368g
gene id: 284592:DEHA2D16368g
uniprot id: Q6BRH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP9 family.
messages: RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).
messages: nucleolus

284592:DEHA2C13112g
gene id: 284592:DEHA2C13112g
uniprot id: Q6BU73
names: Similarity
messages: Belongs to the peptidase S10 family.

284592:DEHA2G02750g
gene id: 284592:DEHA2G02750g
uniprot id: Q6BJF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

284592:DEHA2B03454g
gene id: 284592:DEHA2B03454g
uniprot id: Q6BXF5
names: Similarity
messages: Belongs to the SMP-30/CGR1 family.

284592:DEHA2D10868g
gene id: 284592:DEHA2D10868g
uniprot id: B5RTG9
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C09262g
gene id: 284592:DEHA2C09262g
uniprot id: Q6BUN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284592:DEHA2F19668g
gene id: 284592:DEHA2F19668g
uniprot id: Q6BKR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: nuclear pore complex

284592:DEHA2A01716g
gene id: 284592:DEHA2A01716g
uniprot id: Q6BZF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the SRB8-11 complex, which itself associates with the Mediator complex.
messages: Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
messages: Nucleus

284592:DEHA2B11022g
gene id: 284592:DEHA2B11022g
uniprot id: Q6BWI6
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S1 family.

284592:DEHA2F02376g
gene id: 284592:DEHA2F02376g
uniprot id: Q6BMV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Endoplasmic reticulum membrane
messages: May be involved in specific transport of UDP-Gal from the cytosol to the Golgi lumen. Involved in the maintenance of optimal conditions for the folding of secretory pathway proteins in the endoplasmic reticulum (By similarity).

284592:DEHA2G17314g
gene id: 284592:DEHA2G17314g
uniprot id: Q6BHM9
names: Similarity
messages: Belongs to the XPC family.

284592:DEHA2F24662g
gene id: 284592:DEHA2F24662g
uniprot id: B5RUN4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

284592:DEHA2B13860g
gene id: 284592:DEHA2B13860g
uniprot id: Q6BW70
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

284592:DEHA2F19822g
gene id: 284592:DEHA2F19822g
uniprot id: Q6BKR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

284592:DEHA2C09042g
gene id: 284592:DEHA2C09042g
uniprot id: Q6BUP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion matrix

284592:DEHA2E01562g
gene id: 284592:DEHA2E01562g
uniprot id: Q6BQX4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284592:DEHA2C09878g
gene id: 284592:DEHA2C09878g
uniprot id: Q6BUK6
names: Subcellular Location Annotation
messages: Mitochondrion

284592:DEHA2B10780g
gene id: 284592:DEHA2B10780g
uniprot id: Q6BWJ7
names: Similarity
messages: Belongs to the AFG1 ATPase family.

284592:DEHA2F03806g
gene id: 284592:DEHA2F03806g
uniprot id: Q6BMN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

284592:DEHA2D06644g
gene id: 284592:DEHA2D06644g
uniprot id: Q6BSS3
names: Similarity
messages: Belongs to the IUNH family.

284592:DEHA2F19140g
gene id: 284592:DEHA2F19140g
uniprot id: B5RUJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2F24618g
gene id: 284592:DEHA2F24618g
uniprot id: Q6BK60
names: Similarity
messages: Belongs to the hexokinase family.

284592:DEHA2F08338g
gene id: 284592:DEHA2F08338g
uniprot id: Q6BM48
names: Similarity
messages: Belongs to the AAA ATPase family. PCH2 subfamily.

284592:DEHA2E08360g
gene id: 284592:DEHA2E08360g
uniprot id: Q6BQ49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWS1 family.
messages: Nucleus
messages: Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription (By similarity).

284592:DEHA2E13596g
gene id: 284592:DEHA2E13596g
uniprot id: Q6BPH5
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

284592:DEHA2B05918g
gene id: 284592:DEHA2B05918g
uniprot id: Q6BX51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

284592:DEHA2D19338g
gene id: 284592:DEHA2D19338g
uniprot id: B5RTP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2E11220g
gene id: 284592:DEHA2E11220g
uniprot id: Q6BPS4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

284592:DEHA2C08756g
gene id: 284592:DEHA2C08756g
uniprot id: Q6BUR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAD52 family.
messages: Interacts with RAD51 and RAD52.
messages: Involved in the repair of double-strand breaks in DNA during vegetative growth via recombination and single-strand annealing. Anneals complementary single-stranded DNA.
messages: Nucleus

284592:DEHA2B08734g
gene id: 284592:DEHA2B08734g
uniprot id: Q6BWT4
names: Subcellular Location Annotation
messages: Peroxisome membrane

284592:DEHA2E05852g
gene id: 284592:DEHA2E05852g
uniprot id: Q6BQE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRD1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2C06028g
gene id: 284592:DEHA2C06028g
uniprot id: Q6BV19
names: Similarity
messages: Belongs to the peptidase C48 family.

284592:DEHA2A06336g
gene id: 284592:DEHA2A06336g
uniprot id: B5RSR2
names: Similarity
messages: Belongs to the BMT family.

284592:DEHA2D08998g
gene id: 284592:DEHA2D08998g
uniprot id: Q6BSG5
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2B14190g
gene id: 284592:DEHA2B14190g
uniprot id: Q6BW57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NOP14 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity).
messages: nucleolus

284592:DEHA2E09174g
gene id: 284592:DEHA2E09174g
uniprot id: Q6BQ13
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

284592:DEHA2G24706g
gene id: 284592:DEHA2G24706g
uniprot id: B5RV02
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

284592:DEHA2D13002g
gene id: 284592:DEHA2D13002g
uniprot id: Q6BRY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRM44 family.
messages: Cytoplasm
messages: Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.

284592:DEHA2E14410g
gene id: 284592:DEHA2E14410g
uniprot id: Q6BPD8
names: Similarity
messages: Belongs to the YIP1 family.

284592:DEHA2C01628g
gene id: 284592:DEHA2C01628g
uniprot id: Q6BVL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

284592:DEHA2B11748g
gene id: 284592:DEHA2B11748g
uniprot id: Q6BWF5
names: Similarity
messages: Belongs to the SEN54 family.

284592:DEHA2E15312g
gene id: 284592:DEHA2E15312g
uniprot id: Q6BP99
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

284592:DEHA2E20548g
gene id: 284592:DEHA2E20548g
uniprot id: Q6BNM5
names: Subcellular Location Annotation
messages: Cytoplasm

284592:DEHA2C04620g
gene id: 284592:DEHA2C04620g
uniprot id: Q6BV82
names: Similarity
messages: Belongs to the CBP3 family.

284592:DEHA2E08448g
gene id: 284592:DEHA2E08448g
uniprot id: Q6BQ46
names: Similarity
messages: Belongs to the FMO family.

284592:DEHA2C03784g
gene id: 284592:DEHA2C03784g
uniprot id: Q6BVC3
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C04818g
gene id: 284592:DEHA2C04818g
uniprot id: Q6BV73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284592:DEHA2G12562g
gene id: 284592:DEHA2G12562g
uniprot id: Q6BI90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family.
messages: Component of the nucleoplasmic and cytoplasmic pre-60S ribosomal particles.
messages: Cytoplasm
messages: Nucleus
messages: Probable metalloprotease involved in proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit. Accompanies the pre-60S particles to the cytoplasm (By similarity).

284592:DEHA2C15004g
gene id: 284592:DEHA2C15004g
uniprot id: Q6BTY3
names: Similarity
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.

284592:DEHA2D01606g
gene id: 284592:DEHA2D01606g
uniprot id: Q6BTD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

284592:DEHA2G10120g
gene id: 284592:DEHA2G10120g
uniprot id: Q6BII5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: Cytoplasm
messages: Involved in nuclear export, actin cytoskeleton organization and vesicular transport.
messages: Nucleus

284592:DEHA2C10428g
gene id: 284592:DEHA2C10428g
uniprot id: Q6BUI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM23 family.
messages: Mitochondrion

284592:DEHA2D03190g
gene id: 284592:DEHA2D03190g
uniprot id: Q6BT64
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

284592:DEHA2D03278g
gene id: 284592:DEHA2D03278g
uniprot id: Q6BT60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284592:DEHA2E04180g
gene id: 284592:DEHA2E04180g
uniprot id: Q6BQL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2D04422g
gene id: 284592:DEHA2D04422g
uniprot id: Q6BT11
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynurenine formamidase family.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
messages: Homodimer.
messages: The main chain amide nitrogen atoms of the second glycine and its adjacent residue in the HGGXW motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.

284592:DEHA2G18018g
gene id: 284592:DEHA2G18018g
uniprot id: Q6BHJ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer; composed of 3 copies of TIM8 and 3 copies of TIM13, named soluble 70 kDa complex. Associates with the TIM22 complex, whose core is composed of TIM22 and TIM54. Interacts with the transmembrane regions of multi-pass transmembrane proteins in transit (By similarity).
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8-TIM13 complex is non essential and only mediates the import of few proteins, while the predominant TIM9-TIM10 70 kDa complex is crucial and mediates the import of much more proteins (By similarity).
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. However, during the transit of TIM13 from cytoplasm into mitochondrion, the Cys residues probably coordinate zinc, thereby preventing folding and allowing its transfer across mitochondrial outer membrane (By similarity).

284592:DEHA2C02838g
gene id: 284592:DEHA2C02838g
uniprot id: Q6BVG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane

284592:DEHA2D09702g
gene id: 284592:DEHA2D09702g
uniprot id: Q6BSD4
names: Similarity
messages: Belongs to the cyclin family.

284592:DEHA2G03564g
gene id: 284592:DEHA2G03564g
uniprot id: Q6BJC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

284592:DEHA2C06116g
gene id: 284592:DEHA2C06116g
uniprot id: Q6BV15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

284592:DEHA2F16896g
gene id: 284592:DEHA2F16896g
uniprot id: Q6BL26
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

284592:DEHA2F12232g
gene id: 284592:DEHA2F12232g
uniprot id: Q6BLM5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284592:DEHA2D18964g
gene id: 284592:DEHA2D18964g
uniprot id: B5RTN1
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E17710g
gene id: 284592:DEHA2E17710g
uniprot id: Q6BP00
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

284592:DEHA2D15224g
gene id: 284592:DEHA2D15224g
uniprot id: Q6BRM6
names: Similarity
messages: Belongs to the PGA52 family.

284592:DEHA2F13486g
gene id: 284592:DEHA2F13486g
uniprot id: B5RUG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

284592:DEHA2A02112g
gene id: 284592:DEHA2A02112g
uniprot id: Q6BZD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
messages: Nucleus

284592:DEHA2D12430g
gene id: 284592:DEHA2D12430g
uniprot id: Q6BS09
names: Function
names: Similarity
messages: Belongs to the VPS13 family.
messages: Mediates the transfer of lipids between membranes at organelle contact sites. May play a role in mitochondrial lipid homeostasis.

284592:DEHA2F09790g
gene id: 284592:DEHA2F09790g
uniprot id: Q6BLY4
names: Similarity
messages: Belongs to the BolA/IbaG family.

284592:DEHA2G19052g
gene id: 284592:DEHA2G19052g
uniprot id: Q6BHF3
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

284592:DEHA2B07106g
gene id: 284592:DEHA2B07106g
uniprot id: Q6BX02
names: Function
names: Similarity
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.

284592:DEHA2F00176g
gene id: 284592:DEHA2F00176g
uniprot id: Q6BN51
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

284592:DEHA2B07414g
gene id: 284592:DEHA2B07414g
uniprot id: Q6BWY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM36 family.
messages: Mitochondrion membrane

284592:DEHA2G04312g
gene id: 284592:DEHA2G04312g
uniprot id: B5RV29
names: Similarity
messages: Belongs to the oxoprolinase family.

284592:DEHA2F15444g
gene id: 284592:DEHA2F15444g
uniprot id: Q6BL89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2A10846g
gene id: 284592:DEHA2A10846g
uniprot id: Q6BYB5
names: Similarity
messages: Belongs to the MAD2 family.

284592:DEHA2G11066g
gene id: 284592:DEHA2G11066g
uniprot id: Q6BIE7
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2E10384g
gene id: 284592:DEHA2E10384g
uniprot id: B5RTZ2
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.

284592:DEHA2E09350g
gene id: 284592:DEHA2E09350g
uniprot id: Q6BQ05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Mitochondrion inner membrane

284592:DEHA2C15752g
gene id: 284592:DEHA2C15752g
uniprot id: B5RTC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

284592:DEHA2D15884g
gene id: 284592:DEHA2D15884g
uniprot id: Q6BRJ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

284592:DEHA2B02904g
gene id: 284592:DEHA2B02904g
uniprot id: Q6BXH8
names: PTM
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.
messages: Phosphorylated.

284592:DEHA2A10142g
gene id: 284592:DEHA2A10142g
uniprot id: B5RSU4
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2E09834g
gene id: 284592:DEHA2E09834g
uniprot id: Q6BPY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with cytochrome c oxidase (complex IV, CIV).
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Does not seem to have protease activity as it lacks the zinc-binding site.
messages: Mitochondrion inner membrane

284592:DEHA2A01672g
gene id: 284592:DEHA2A01672g
uniprot id: Q6BZF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). Also a component of the nuclear pore complex (By similarity).
messages: Belongs to the dynein light chain family.
messages: Homodimer. Cytoplasmic dynein consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits which present intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs). Component of the nuclear pore complex (NPC). NPC constitutes the exclusive means of nucleocytoplasmic transport. NPCs allow the passive diffusion of ions and small molecules and the active, nuclear transport receptor-mediated bidirectional transport of macromolecules such as proteins, RNAs, ribonucleoparticles (RNPs), and ribosomal subunits across the nuclear envelope. Due to its 8-fold rotational symmetry, all subunits are present with 8 copies or multiples thereof.
messages: cytoskeleton
messages: nuclear pore complex

284592:DEHA2C16368g
gene id: 284592:DEHA2C16368g
uniprot id: Q6BTS0
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

284592:DEHA2G23914g
gene id: 284592:DEHA2G23914g
uniprot id: Q6BGU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

284592:DEHA2G04598g
gene id: 284592:DEHA2G04598g
uniprot id: Q6BJ76
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

284592:DEHA2G12430g
gene id: 284592:DEHA2G12430g
uniprot id: Q6BI97
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

284592:DEHA2G07788g
gene id: 284592:DEHA2G07788g
uniprot id: Q6BIT5
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

284592:DEHA2D12760g
gene id: 284592:DEHA2D12760g
uniprot id: Q6BRZ2
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

284592:DEHA2D07348g
gene id: 284592:DEHA2D07348g
uniprot id: Q6BSP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

284592:DEHA2F08228g
gene id: 284592:DEHA2F08228g
uniprot id: Q6BM53
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

284592:DEHA2C02992g
gene id: 284592:DEHA2C02992g
uniprot id: Q6BVF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA.
messages: nucleolus

284592:DEHA2A01606g
gene id: 284592:DEHA2A01606g
uniprot id: Q6BZG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.
messages: Nucleus

284592:DEHA2F01496g
gene id: 284592:DEHA2F01496g
uniprot id: Q6BMZ2
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

284592:DEHA2F02090g
gene id: 284592:DEHA2F02090g
uniprot id: Q6BMW5
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

284592:DEHA2B09240g
gene id: 284592:DEHA2B09240g
uniprot id: Q6BWR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2G15180g
gene id: 284592:DEHA2G15180g
uniprot id: Q6BHX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

284592:DEHA2F03564g
gene id: 284592:DEHA2F03564g
uniprot id: Q6BMQ0
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

284592:DEHA2F05742g
gene id: 284592:DEHA2F05742g
uniprot id: Q6BMG0
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

284592:DEHA2A08668g
gene id: 284592:DEHA2A08668g
uniprot id: Q6BYL4
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

284592:DEHA2F13112g
gene id: 284592:DEHA2F13112g
uniprot id: Q6BLI7
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

284592:DEHA2G17006g
gene id: 284592:DEHA2G17006g
uniprot id: Q6BHP3
names: Subcellular Location Annotation
messages: nuclear pore complex

284592:DEHA2C13706g
gene id: 284592:DEHA2C13706g
uniprot id: Q6BU45
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

284592:DEHA2B14542g
gene id: 284592:DEHA2B14542g
uniprot id: Q6BW41
names: Similarity
messages: Belongs to the KNR4/SMI1 family.

284592:DEHA2E17006g
gene id: 284592:DEHA2E17006g
uniprot id: Q6BP29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: actin patch

284592:DEHA2F07942g
gene id: 284592:DEHA2F07942g
uniprot id: B5RUB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. In yeast, the dimeric form of ATP synthase consists of 17 polypeptides: alpha, beta, gamma, delta, epsilon, 4 (B), 5 (OSCP), 6 (A), 8, 9 (C), d, E (Tim11), f, g, h, i/j and k.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

284592:DEHA2E23870g
gene id: 284592:DEHA2E23870g
uniprot id: Q6BN82
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

284592:DEHA2B06974g
gene id: 284592:DEHA2B06974g
uniprot id: Q6BX07
names: Similarity
messages: Belongs to the multicopper oxidase family.

284592:DEHA2F25234g
gene id: 284592:DEHA2F25234g
uniprot id: Q6BK34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
messages: Component of the HAT-B complex composed of at least HAT1 and HAT2. The HAT-B complex binds to histone H4 tail.
messages: Cytoplasm
messages: Nucleus
messages: Regulatory subunit of the histone acetylase B (HAT-B) complex. The complex acetylates 'Lys-12' of histone H4 which is required for telomeric silencing.

284592:DEHA2G12078g
gene id: 284592:DEHA2G12078g
uniprot id: Q6BIB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

284592:DEHA2F20394g
gene id: 284592:DEHA2F20394g
uniprot id: B5RUK1
names: Similarity
messages: Belongs to the citrate synthase family.

284592:DEHA2D18788g
gene id: 284592:DEHA2D18788g
uniprot id: Q6BR68
names: Similarity
messages: Belongs to the GST superfamily.

284592:DEHA2D02948g
gene id: 284592:DEHA2D02948g
uniprot id: Q6BT75
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

284592:DEHA2C03168g
gene id: 284592:DEHA2C03168g
uniprot id: Q6BVE8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284592:DEHA2B06754g
gene id: 284592:DEHA2B06754g
uniprot id: Q6BX17
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

284592:DEHA2A03344g
gene id: 284592:DEHA2A03344g
uniprot id: Q6BZ80
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

284592:DEHA2A08954g
gene id: 284592:DEHA2A08954g
uniprot id: Q6BYK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

284592:DEHA2F09966g
gene id: 284592:DEHA2F09966g
uniprot id: Q6BLX3
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

284592:DEHA2F22066g
gene id: 284592:DEHA2F22066g
uniprot id: Q6BKG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Mitochondrion inner membrane

284592:DEHA2B10208g
gene id: 284592:DEHA2B10208g
uniprot id: Q6BWM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COPE family.
messages: Cytoplasm
messages: Membrane
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

284592:DEHA2A01914g
gene id: 284592:DEHA2A01914g
uniprot id: Q6BZE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LU7TM family.
messages: Membrane

284592:DEHA2C14806g
gene id: 284592:DEHA2C14806g
uniprot id: Q6BTZ2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

284592:DEHA2G14014g
gene id: 284592:DEHA2G14014g
uniprot id: Q6BI22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

284592:DEHA2C02332g
gene id: 284592:DEHA2C02332g
uniprot id: Q6BVI8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated to ATG12; which is essential for autophagy.
messages: Conjugated with ATG12.
messages: Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy). Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).
messages: Preautophagosomal structure membrane

284592:DEHA2C14960g
gene id: 284592:DEHA2C14960g
uniprot id: B5RTC0
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

284592:DEHA2G22132g
gene id: 284592:DEHA2G22132g
uniprot id: Q6BH15
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284592:DEHA2G18348g
gene id: 284592:DEHA2G18348g
uniprot id: Q6BHI3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

284592:DEHA2E20284g
gene id: 284592:DEHA2E20284g
uniprot id: Q6BNN5
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

284592:DEHA2C10692g
gene id: 284592:DEHA2C10692g
uniprot id: Q6BUH1
names: Similarity
messages: Belongs to the FUN14 family.

284592:DEHA2F01342g
gene id: 284592:DEHA2F01342g
uniprot id: Q6BMZ9
names: Similarity
messages: Belongs to the glutaminase PdxT/SNO family.

284592:DEHA2B16126g
gene id: 284592:DEHA2B16126g
uniprot id: Q6BVW7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

284592:DEHA2F20636g
gene id: 284592:DEHA2F20636g
uniprot id: Q6BKM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

284592:DEHA2D07568g
gene id: 284592:DEHA2D07568g
uniprot id: Q6BSN0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

284592:DEHA2A05324g
gene id: 284592:DEHA2A05324g
uniprot id: Q6BZ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC6 subfamily.
messages: Chromosome
messages: Nucleus

284592:DEHA2E06710g
gene id: 284592:DEHA2E06710g
uniprot id: Q6BQC0
names: Similarity
messages: Belongs to the pyridoxine kinase family.

284592:DEHA2G20284g
gene id: 284592:DEHA2G20284g
uniprot id: Q6BH97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.

284592:DEHA2D00748g
gene id: 284592:DEHA2D00748g
uniprot id: Q6BTG8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

284592:DEHA2G04158g
gene id: 284592:DEHA2G04158g
uniprot id: Q6BJ94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHE9 family.
messages: Homooligomer.
messages: Mitochondrion inner membrane
messages: Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed (By similarity).

284592:DEHA2A03454g
gene id: 284592:DEHA2A03454g
uniprot id: Q6BZ77
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity).
messages: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284592:DEHA2D14256g
gene id: 284592:DEHA2D14256g
uniprot id: Q6BKD9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

284592:DEHA2A10186g
gene id: 284592:DEHA2A10186g
uniprot id: Q6BYE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ASF1 family.
messages: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
messages: Interacts with histone H3 and histone H4.
messages: Nucleus

284592:DEHA2C12276g
gene id: 284592:DEHA2C12276g
uniprot id: Q6BUB1
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2D12694g
gene id: 284592:DEHA2D12694g
uniprot id: Q6BRZ5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation of histone H3 leads to transcriptional activation. H3K14ac formation by GCN5 is promoted by H3S10ph. H3K14ac can also be formed by ESA1. H3K56ac formation occurs predominantly in newly synthesized H3 molecules during G1, S and G2/M of the cell cycle and may be involved in DNA repair (By similarity).
messages: Belongs to the histone H3 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).
messages: Mono-, di- and trimethylated by the COMPASS complex to form H3K4me1/2/3. H3K4me activates gene expression by regulating transcription elongation and plays a role in telomere length maintenance. H3K4me enrichment correlates with transcription levels, and occurs in a 5' to 3' gradient with H3K4me3 enrichment at the 5'-end of genes, shifting to H3K4me2 and then H3K4me1. Methylated by SET2 to form H3K36me. H3K36me represses gene expression. Methylated by DOT1 to form H3K79me. H3K79me is required for association of SIR proteins with telomeric regions and for telomeric silencing. The COMPASS-mediated formation of H3K4me2/3 and the DOT1-mediated formation of H3K79me require H2BK123ub1 (By similarity).
messages: Nucleus
messages: Phosphorylated by IPL1 to form H3S10ph. H3S10ph promotes subsequent H3K14ac formation by GCN5 and is required for transcriptional activation through TBP recruitment to the promoters (By similarity).
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA (By similarity).
messages: To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H3K4me1/2/3 = mono-, di- and trimethylated Lys-5; H3K9ac = acetylated Lys-10; H3K9me1 = monomethylated Lys-10; H3S10ph = phosphorylated Ser-11; H3K14ac = acetylated Lys-15; H3K14me2 = dimethylated Lys-15; H3K18ac = acetylated Lys-19; H3K18me1 = monomethylated Lys-19; H3K23ac = acetylated Lys-24; H3K23me1 = monomethylated Lys-24; H3K27ac = acetylated Lys-28; H3K27me1/2/3 = mono-, di- and trimethylated Lys-28; H3K36ac = acetylated Lys-37; H3K36me1/2/3 = mono-, di- and trimethylated Lys-37; H3K56ac = acetylated Lys-57; H3K64ac = acetylated Lys-65; H3K79me1/2/3 = mono-, di- and trimethylated Lys-80.

284592:DEHA2D06534g
gene id: 284592:DEHA2D06534g
uniprot id: Q6BSS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
messages: Cytoplasm
messages: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates. Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins. Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo.
messages: Nucleus

284592:DEHA2F21208g
gene id: 284592:DEHA2F21208g
uniprot id: Q6BKK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with TAN1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

284592:DEHA2F23870g
gene id: 284592:DEHA2F23870g
uniprot id: Q6BK91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

284592:DEHA2B14146g
gene id: 284592:DEHA2B14146g
uniprot id: B5RSW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKN1/KRE6 family.
messages: Membrane

284592:DEHA2D12210g
gene id: 284592:DEHA2D12210g
uniprot id: Q6BS19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

284592:DEHA2F25894g
gene id: 284592:DEHA2F25894g
uniprot id: Q6BK06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STE12 transcription factor family.
messages: Nucleus

284592:DEHA2B08008g
gene id: 284592:DEHA2B08008g
uniprot id: Q6BWW5
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

284592:DEHA2C11682g
gene id: 284592:DEHA2C11682g
uniprot id: Q6BUD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

284592:DEHA2C06402g
gene id: 284592:DEHA2C06402g
uniprot id: Q6BV04
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

284592:DEHA2E17952g
gene id: 284592:DEHA2E17952g
uniprot id: Q6BNY7
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

284592:DEHA2C05500g
gene id: 284592:DEHA2C05500g
uniprot id: Q6BV43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

284592:DEHA2B14278g
gene id: 284592:DEHA2B14278g
uniprot id: Q6BW54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284592:DEHA2G07458g
gene id: 284592:DEHA2G07458g
uniprot id: Q6BIU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

284592:DEHA2A07590g
gene id: 284592:DEHA2A07590g
uniprot id: B5RSS4
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

284592:DEHA2A07832g
gene id: 284592:DEHA2A07832g
uniprot id: Q6BYP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in cytoplasm to vacuole transport (Cvt) and autophagy by mediating both proteolytic activation and delipidation of ATG8. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. The protease activity is required for proteolytic activation of ATG8: cleaves the C-terminal amino acid of ATG8 to reveal a C-terminal glycine. ATG8 ubiquitin-like activity requires the exposure of the glycine at the C-terminus for its conjugation to phosphatidylethanolamine (PE) and its insertion to membranes, which is necessary for autophagy. The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy. In addition to the protease activity, also catalyzes deconjugation of PE-conjugated forms of ATG8 during macroautophagy: ATG8 delipidation is required to release the protein from membranes, which facilitates multiple events during macroautophagy, and especially for efficient autophagosome biogenesis, the assembly of ATG9-containing tubulovesicular clusters into phagophores/autophagosomes, and for the disassembly of PAS-associated ATG components. ATG8 delipidation by ATG4 also recycles ATG8-PE generated on inappropriate membranes to maintain a reservoir of unlipidated ATG8 that is required for autophagosome formation at the PAS.
messages: Cytoplasm
messages: Nucleus
messages: Preautophagosomal structure

284592:DEHA2G19316g
gene id: 284592:DEHA2G19316g
uniprot id: Q6BHE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

284592:DEHA2G14036g
gene id: 284592:DEHA2G14036g
uniprot id: Q6BI21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus

284592:DEHA2G15466g
gene id: 284592:DEHA2G15466g
uniprot id: Q6BHV6
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

284592:DEHA2G14454g
gene id: 284592:DEHA2G14454g
uniprot id: Q6BI05
names: Function
names: Subcellular Location Annotation
messages: Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation.
messages: Nucleus

284592:DEHA2C13882g
gene id: 284592:DEHA2C13882g
uniprot id: Q6BU37
names: Similarity
messages: Belongs to the peptidase S8 family.

284592:DEHA2F26378g
gene id: 284592:DEHA2F26378g
uniprot id: B5RUP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

284592:DEHA2D10758g
gene id: 284592:DEHA2D10758g
uniprot id: Q6BS88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis.
messages: Nucleus

284592:DEHA2C06644g
gene id: 284592:DEHA2C06644g
uniprot id: Q6BUZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLD7 family.
messages: Nucleus
messages: spindle pole

284592:DEHA2G22418g
gene id: 284592:DEHA2G22418g
uniprot id: Q6BH02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix.
messages: Mitochondrion inner membrane

284592:DEHA2A12958g
gene id: 284592:DEHA2A12958g
uniprot id: Q6BY27
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing.
messages: Associates with polysomes.
messages: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
messages: Cytoplasm
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284592:DEHA2G02706g
gene id: 284592:DEHA2G02706g
uniprot id: Q6BJG0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284592:DEHA2A08888g
gene id: 284592:DEHA2A08888g
uniprot id: Q6BYK3
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2D17776g
gene id: 284592:DEHA2D17776g
uniprot id: B5RTK4
names: Similarity
messages: Belongs to the small Tim family.

284592:DEHA2C16060g
gene id: 284592:DEHA2C16060g
uniprot id: Q6BTT4
names: Similarity
messages: Belongs to the OSBP family.

284592:DEHA2F06270g
gene id: 284592:DEHA2F06270g
uniprot id: Q6BMD8
names: Similarity
messages: Belongs to the Luc7 family.

284592:DEHA2C02728g
gene id: 284592:DEHA2C02728g
uniprot id: Q6BVH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking.

284592:DEHA2A09834g
gene id: 284592:DEHA2A09834g
uniprot id: Q6BYG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

284592:DEHA2C15796g
gene id: 284592:DEHA2C15796g
uniprot id: Q6BTU6
names: Similarity
messages: Belongs to the NifU family.

284592:DEHA2F05016g
gene id: 284592:DEHA2F05016g
uniprot id: Q6BMJ1
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

284592:DEHA2F06028g
gene id: 284592:DEHA2F06028g
uniprot id: Q6BME9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIF1/spd1 family.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2E09768g
gene id: 284592:DEHA2E09768g
uniprot id: B5RTY7
names: Similarity
messages: Belongs to the actin family.

284592:DEHA2E07436g
gene id: 284592:DEHA2E07436g
uniprot id: Q6BQ86
names: Similarity
messages: Belongs to the AAA ATPase family.

284592:DEHA2G12166g
gene id: 284592:DEHA2G12166g
uniprot id: Q6BIB1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

284592:DEHA2D16786g
gene id: 284592:DEHA2D16786g
uniprot id: Q6BRF4
names: Function
names: Subcellular Location Annotation
messages: May be involved in the mitochondrial lipid metabolism.
messages: Mitochondrion

284592:DEHA2C15774g
gene id: 284592:DEHA2C15774g
uniprot id: B5RTC6
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2G06402g
gene id: 284592:DEHA2G06402g
uniprot id: Q6BIZ6
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284592:DEHA2E14014g
gene id: 284592:DEHA2E14014g
uniprot id: Q6BPF5
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2F03850g
gene id: 284592:DEHA2F03850g
uniprot id: Q6BMN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDS23 family.
messages: Cytoplasm
messages: Involved in DNA replication and cell separation.
messages: Nucleus

284592:DEHA2F03498g
gene id: 284592:DEHA2F03498g
uniprot id: Q6BMQ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes. The CSN complex is involved in the regulation of the mating pheromone response.
messages: Component of the COP9 signalosome (CSN) complex.
messages: Cytoplasm
messages: Nucleus
messages: The JAMM motif is essential for the protease activity of the CSN complex resulting in deneddylation of cullins. It constitutes the catalytic center of the complex (By similarity).

284592:DEHA2C01650g
gene id: 284592:DEHA2C01650g
uniprot id: Q6BVL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

284592:DEHA2B00638g
gene id: 284592:DEHA2B00638g
uniprot id: Q6BXS4
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2B15752g
gene id: 284592:DEHA2B15752g
uniprot id: Q6BVY4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: Nucleus
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

284592:DEHA2A09746g
gene id: 284592:DEHA2A09746g
uniprot id: Q6BYG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin-conjugating enzyme family.
messages: Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in degradation of misfolded or regulated proteins localized in the endoplasmic reticulum (ER) lumen or membrane via the ubiquitin-proteasome system. Cognate E2 conjugating enzyme for the DOA10 ubiquitin ligase complex, which is part of the ERAD-C pathway responsible for the rapid degradation of membrane proteins with misfolded cytoplasmic domains.
messages: Endoplasmic reticulum membrane

284592:DEHA2F14366g
gene id: 284592:DEHA2F14366g
uniprot id: Q6BLD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

284592:DEHA2G23496g
gene id: 284592:DEHA2G23496g
uniprot id: Q6BGW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

284592:DEHA2F21670g
gene id: 284592:DEHA2F21670g
uniprot id: Q6BKI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

284592:DEHA2F19272g
gene id: 284592:DEHA2F19272g
uniprot id: Q6BKT9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

284592:DEHA2F00792g
gene id: 284592:DEHA2F00792g
uniprot id: Q6BN25
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

284592:DEHA2A01144g
gene id: 284592:DEHA2A01144g
uniprot id: Q6BZI1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

284592:DEHA2G03300g
gene id: 284592:DEHA2G03300g
uniprot id: Q6BJD2
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284592:DEHA2G08800g
gene id: 284592:DEHA2G08800g
uniprot id: Q6BIP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Cytoplasm
messages: Nucleus
messages: Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein RAD18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats. Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs (By similarity).

284592:DEHA2D12254g
gene id: 284592:DEHA2D12254g
uniprot id: Q6BS17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

284592:DEHA2E15114g
gene id: 284592:DEHA2E15114g
uniprot id: Q6BPA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane

284592:DEHA2B01716g
gene id: 284592:DEHA2B01716g
uniprot id: Q6BXM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

284592:DEHA2A14212g
gene id: 284592:DEHA2A14212g
uniprot id: Q6BXX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AATF family.
messages: nucleolus

284592:DEHA2D13068g
gene id: 284592:DEHA2D13068g
uniprot id: Q6BRX8
names: Function
names: Similarity
messages: Belongs to the VPS16 family.
messages: Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.

284592:DEHA2C08514g
gene id: 284592:DEHA2C08514g
uniprot id: Q6BUS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

284592:DEHA2F19316g
gene id: 284592:DEHA2F19316g
uniprot id: Q6BKT7
names: Similarity
messages: Belongs to the peptidase M24 family.

284592:DEHA2D13794g
gene id: 284592:DEHA2D13794g
uniprot id: Q6BRU3
names: Similarity
messages: Belongs to the UPP synthase family.

284592:DEHA2E13288g
gene id: 284592:DEHA2E13288g
uniprot id: Q6BPI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the timeless family.
messages: Involved in chromosome segregation during meiosis and DNA damage repair.
messages: Nucleus

284592:DEHA2G00308g
gene id: 284592:DEHA2G00308g
uniprot id: Q6BJS7
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2C01034g
gene id: 284592:DEHA2C01034g
uniprot id: Q6BVP5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

284592:DEHA2E15972g
gene id: 284592:DEHA2E15972g
uniprot id: Q6BP73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

284592:DEHA2B04906g
gene id: 284592:DEHA2B04906g
uniprot id: Q6BX94
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

284592:DEHA2F16676g
gene id: 284592:DEHA2F16676g
uniprot id: Q6BL36
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

284592:DEHA2B02706g
gene id: 284592:DEHA2B02706g
uniprot id: Q6BXI5
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

284592:DEHA2A10472g
gene id: 284592:DEHA2A10472g
uniprot id: Q6BYD1
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2B05632g
gene id: 284592:DEHA2B05632g
uniprot id: Q6BX64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mis12 family.
messages: kinetochore

284592:DEHA2B03190g
gene id: 284592:DEHA2B03190g
uniprot id: Q6BXG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
messages: Heterodimer of an alpha and a beta subunit.
messages: Nucleus
messages: cytoskeleton

284592:DEHA2B15906g
gene id: 284592:DEHA2B15906g
uniprot id: Q6BVX6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284592:DEHA2D03784g
gene id: 284592:DEHA2D03784g
uniprot id: Q6BT38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MRG family.
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
messages: Nucleus

284592:DEHA2E10934g
gene id: 284592:DEHA2E10934g
uniprot id: Q6BPT7
names: Subcellular Location Annotation
messages: Nucleus

284592:DEHA2G14058g
gene id: 284592:DEHA2G14058g
uniprot id: Q6BI20
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+) is required for catalysis and for stabilizing the dimer.

284592:DEHA2D01166g
gene id: 284592:DEHA2D01166g
uniprot id: Q6BTF1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

284592:DEHA2G20416g
gene id: 284592:DEHA2G20416g
uniprot id: Q6BH91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EFG1 family.
messages: Involved in rRNA processing.
messages: nucleolus

284592:DEHA2E09878g
gene id: 284592:DEHA2E09878g
uniprot id: Q6BPY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

284592:DEHA2B08030g
gene id: 284592:DEHA2B08030g
uniprot id: Q6BWW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX1 family.
messages: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
messages: Forms a heterodimer with SLX4.
messages: Nucleus

284592:DEHA2D16588g
gene id: 284592:DEHA2D16588g
uniprot id: Q6BRG3
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated by ESA1 to form H2AK4ac and H2AK7ac.
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: In contrast to vertebrates and insects, its C-terminus is not monoubiquitinated.
messages: Nucleus
messages: Phosphorylated to form H2AS128ph (gamma-H2A) in response to DNA double-strand breaks (DSBs) generated by exogenous genotoxic agents and by stalled replication forks. Phosphorylation is dependent on the DNA damage checkpoint kinases MEC1/ATR and TEL1/ATM, spreads on either side of a detected DSB site and may mark the surrounding chromatin for recruitment of proteins required for DNA damage signaling and repair. Gamma-H2A is removed from the DNA prior to the strand invasion-primer extension step of the repair process and subsequently dephosphorylated. Dephosphorylation is necessary for efficient recovery from the DNA damage checkpoint (By similarity).
messages: The [ST]-Q motif constitutes a recognition sequence for kinases from the PI3/PI4-kinase family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H2AK4ac = acetylated Lys-5; H2AK7ac = acetylated Lys-7; H2AS128ph = phosphorylated Ser-128.

284592:DEHA2D11858g
gene id: 284592:DEHA2D11858g
uniprot id: Q6BS36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Cytoplasm

284592:DEHA2B09658g
gene id: 284592:DEHA2B09658g
uniprot id: Q6BWP6
names: Similarity
messages: Belongs to the proteasome subunit S14 family.

284592:DEHA2E01012g
gene id: 284592:DEHA2E01012g
uniprot id: W0TYS1
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284592:DEHA2C05038g
gene id: 284592:DEHA2C05038g
uniprot id: Q6BV64
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

284592:DEHA2F26048g
gene id: 284592:DEHA2F26048g
uniprot id: Q6BJZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YSP2 family.
messages: Membrane

284592:DEHA2G12870g
gene id: 284592:DEHA2G12870g
uniprot id: Q6BI75
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

284592:DEHA2G16808g
gene id: 284592:DEHA2G16808g
uniprot id: Q6BHQ0
names: Subcellular Location Annotation
messages: Membrane

284592:DEHA2F02750g
gene id: 284592:DEHA2F02750g
uniprot id: B5RU83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

284592:DEHA2E05874g
gene id: 284592:DEHA2E05874g
uniprot id: Q6BQE2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

284592:DEHA2G10098g
gene id: 284592:DEHA2G10098g
uniprot id: B5RUP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

284592:DEHA2G15994g
gene id: 284592:DEHA2G15994g
uniprot id: B5RUT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

284592:DEHA2B05192g
gene id: 284592:DEHA2B05192g
uniprot id: Q6BX81
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS11 family.
messages: Component of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex. Component of the class C core vacuole/endosome tethering (CORVET) complex.
messages: Vacuole membrane

284592:DEHA2F02420g
gene id: 284592:DEHA2F02420g
uniprot id: Q6BMV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

284592:DEHA2D09900g
gene id: 284592:DEHA2D09900g
uniprot id: Q6BSC4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG3 family.
messages: Cytoplasm
messages: E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8. The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8 from ATG3 to phosphatidylethanolamine (PE). This step is required for the membrane association of ATG8. The formation of the ATG8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt). The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity).
messages: Monomer. Interacts with ATG8 through an intermediate thioester bond through the C-terminal Gly of ATG8. Also interacts with the 40 amino acid C-terminal region of the E1-like ATG7 enzyme. Interacts also with the ATG12-ATG5 conjugate.
messages: The N-terminal region is involved in phosphatidylethanolamine-binding and is required for ATG8-PE conjugation.
messages: The flexible region (FR) is required for ATG7-binding.
messages: The handle region (HR) contains the ATG8 interaction motif (AIM) and mediates binding to ATG8. It is crucial for the cytoplasm-to-vacuole targeting pathway (By similarity).

284592:DEHA2G19690g
gene id: 284592:DEHA2G19690g
uniprot id: Q6BHC2
names: Similarity
messages: Belongs to the peptidase C12 family.