284591:YALI0 E30305g
gene id: 284591:YALI0_E30305g
uniprot id: Q6C427
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LCL3 family.
messages: Membrane
messages: Mitochondrion

284591:YALI0 B04026g
gene id: 284591:YALI0_B04026g
uniprot id: Q6CFT6
names: Similarity
messages: Belongs to the synaptobrevin family.

284591:YALI0 D05049g
gene id: 284591:YALI0_D05049g
uniprot id: Q6CA83
names: Similarity
messages: Belongs to the HEATR5 family.

284591:YALI0 E09174g
gene id: 284591:YALI0_E09174g
uniprot id: Q6C6I9
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 B20196g
gene id: 284591:YALI0_B20196g
uniprot id: Q6CDY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

284591:YALI0 A00979g
gene id: 284591:YALI0_A00979g
uniprot id: Q6CI74
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A05137g
gene id: 284591:YALI0_A05137g
uniprot id: Q6CHT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Mitochondrion inner membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

284591:YALI0 D08382g
gene id: 284591:YALI0_D08382g
uniprot id: Q6C9U1
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284591:YALI0 C14190g
gene id: 284591:YALI0_C14190g
uniprot id: Q6CBZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKN1/KRE6 family.
messages: Membrane

284591:YALI0 F15873g
gene id: 284591:YALI0_F15873g
uniprot id: Q6C1I9
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E11473g
gene id: 284591:YALI0_E11473g
uniprot id: Q6C691
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E00330g
gene id: 284591:YALI0_E00330g
uniprot id: Q6C7J3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B04851g
gene id: 284591:YALI0_B04851g
uniprot id: B5FVB1
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

284591:YALI0 B20240g
gene id: 284591:YALI0_B20240g
uniprot id: Q6CDY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

284591:YALI0 B23320g
gene id: 284591:YALI0_B23320g
uniprot id: Q6CDK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284591:YALI0 D16841g
gene id: 284591:YALI0_D16841g
uniprot id: Q6C8U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MET18/MMS19 family.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus

284591:YALI0 A18810g
gene id: 284591:YALI0_A18810g
uniprot id: Q6CGJ3
names: Similarity
messages: Belongs to the peptidase S10 family.

284591:YALI0 D02079g
gene id: 284591:YALI0_D02079g
uniprot id: Q6CAK1
names: Function
names: Similarity
messages: Belongs to the SNU71 family.
messages: Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway.

284591:YALI0 E15378g
gene id: 284591:YALI0_E15378g
uniprot id: F2Z6I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Peroxisome

284591:YALI0 E24805g
gene id: 284591:YALI0_E24805g
uniprot id: Q6C4P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

284591:YALI0 E11187g
gene id: 284591:YALI0_E11187g
uniprot id: Q6C6A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus

284591:YALI0 F14685g
gene id: 284591:YALI0_F14685g
uniprot id: Q6C1N8
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

284591:YALI0 C16775g
gene id: 284591:YALI0_C16775g
uniprot id: Q6CBP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

284591:YALI0 A01419g
gene id: 284591:YALI0_A01419g
uniprot id: Q6CI60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I LYR family.
messages: Mitochondrion inner membrane

284591:YALI0 C17391g
gene id: 284591:YALI0_C17391g
uniprot id: Q6CBM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

284591:YALI0 A20988g
gene id: 284591:YALI0_A20988g
uniprot id: Q6CGA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284591:YALI0 D23617g
gene id: 284591:YALI0_D23617g
uniprot id: Q6C815
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

284591:YALI0 F29931g
gene id: 284591:YALI0_F29931g
uniprot id: Q6BZY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex, whose core is composed of TIM22 and TIM54, associated with the 70 kDa heterohexamer composed of TIM9 and TIM10 (or TIM8 and TIM13).
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
messages: Mitochondrion inner membrane

284591:YALI0 C16434g
gene id: 284591:YALI0_C16434g
uniprot id: Q6CBQ9
names: Similarity
messages: Belongs to the guanylate kinase family.

284591:YALI0 C21626g
gene id: 284591:YALI0_C21626g
uniprot id: Q6CB62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 C23364g
gene id: 284591:YALI0_C23364g
uniprot id: Q6CAY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

284591:YALI0 D27038g
gene id: 284591:YALI0_D27038g
uniprot id: Q6C7L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane

284591:YALI0 B15840g
gene id: 284591:YALI0_B15840g
uniprot id: Q6CEG4
names: Similarity
messages: Belongs to the AHA1 family.

284591:YALI0 E26081g
gene id: 284591:YALI0_E26081g
uniprot id: Q6C4K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

284591:YALI0 C08899g
gene id: 284591:YALI0_C08899g
uniprot id: Q6CCJ3
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 B03366g
gene id: 284591:YALI0_B03366g
uniprot id: Q6CFV4
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

284591:YALI0 C21890g
gene id: 284591:YALI0_C21890g
uniprot id: Q6CB51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

284591:YALI0 E18876g
gene id: 284591:YALI0_E18876g
uniprot id: Q6C5D9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

284591:YALI0 B21076g
gene id: 284591:YALI0_B21076g
uniprot id: Q6CDU7
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

284591:YALI0 D08206g
gene id: 284591:YALI0_D08206g
uniprot id: Q6C9U9
names: Similarity
messages: Belongs to the lysophospholipase family.

284591:YALI0 A12353g
gene id: 284591:YALI0_A12353g
uniprot id: Q6CH50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284591:YALI0 B02992g
gene id: 284591:YALI0_B02992g
uniprot id: Q6CFW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PAM17 family.
messages: Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Component of the PAM complex, at least composed of mtHsp70 (SSC1), MGE1, TIM44, PAM16, PAM17 and PAM18.
messages: Mitochondrion inner membrane

284591:YALI0 A05555g
gene id: 284591:YALI0_A05555g
uniprot id: Q6CHS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: nucleolus

284591:YALI0 E14443g
gene id: 284591:YALI0_E14443g
uniprot id: Q6C5X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

284591:YALI0 B18414g
gene id: 284591:YALI0_B18414g
uniprot id: Q6CE56
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 B01224g
gene id: 284591:YALI0_B01224g
uniprot id: W0TYP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression.

284591:YALI0 E17985g
gene id: 284591:YALI0_E17985g
uniprot id: Q6C5H6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284591:YALI0 D14520g
gene id: 284591:YALI0_D14520g
uniprot id: Q6C937
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

284591:YALI0 D13882g
gene id: 284591:YALI0_D13882g
uniprot id: Q6C955
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

284591:YALI0 F29491g
gene id: 284591:YALI0_F29491g
uniprot id: Q6BZZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IML2 family.
messages: Cytoplasm
messages: Inclusion body (IB) resident protein that interacts strongly with lipid droplet (LD) proteins. Involved in LD-mediated IB clearing after protein folding stress, probably by enabling access to the IBs of an LD-stored soluble sterol derivative that acts as chaperone in inclusion clearing.
messages: Interacts with lipid droplet proteins.
messages: Nucleus

284591:YALI0 C00825g
gene id: 284591:YALI0_C00825g
uniprot id: Q6CDG0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B18150g
gene id: 284591:YALI0_B18150g
uniprot id: Q6CE68
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F09383g
gene id: 284591:YALI0_F09383g
uniprot id: Q6C2A8
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

284591:YALI0 B15147g
gene id: 284591:YALI0_B15147g
uniprot id: Q6CEJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover (By similarity). Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA (By similarity).
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 E04400g
gene id: 284591:YALI0_E04400g
uniprot id: F2Z675
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S64 family.
messages: Cell membrane
messages: Component of the plasma membrane SPS (SSY1-PTR3-SSY5) amino acid sensor complex.
messages: Protease component of the SPS-sensor system, which regulates the expression of several amino acid-metabolizing enzymes and amino acid- and peptide-permeases in response to extracellular amino acid levels by controlling the activity of two transcription factors, STP1 and STP2. Catalyzes the activation of these transcription factors, which are synthesized as latent cytoplasmic precursors, by proteolytic removal of an N-terminal inhibitory domain containing cytoplasmic retention motifs. SSY5 binds as an inactive protease complex to STP1. In response to extracellular amino acids and dependent on the other SPS-sensor components, the inhibitory propeptide is induced to dissociate, and thereby enables the catalytic domain to process STP1.

284591:YALI0 C00693g
gene id: 284591:YALI0_C00693g
uniprot id: Q6CDG6
names: Similarity
messages: Belongs to the NOP10 family.

284591:YALI0 D15532g
gene id: 284591:YALI0_D15532g
uniprot id: Q6C8Z7
names: Similarity
messages: Belongs to the DSD1 family.

284591:YALI0 F20636g
gene id: 284591:YALI0_F20636g
uniprot id: Q6C0Z0
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.

284591:YALI0 B09295g
gene id: 284591:YALI0_B09295g
uniprot id: W0TYP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP5 family.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 D07392g
gene id: 284591:YALI0_D07392g
uniprot id: Q6C9Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

284591:YALI0 C13926g
gene id: 284591:YALI0_C13926g
uniprot id: Q6CC01
names: Similarity
messages: Belongs to the cyclin family.

284591:YALI0 F26719g
gene id: 284591:YALI0_F26719g
uniprot id: Q6C092
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

284591:YALI0 F05214g
gene id: 284591:YALI0_F05214g
uniprot id: Q6C2T9
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.

284591:YALI0 E19767g
gene id: 284591:YALI0_E19767g
uniprot id: Q6C5A1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

284591:YALI0 F05632g
gene id: 284591:YALI0_F05632g
uniprot id: Q6C2S1
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

284591:YALI0 C02563g
gene id: 284591:YALI0_C02563g
uniprot id: Q6CD97
names: Similarity
messages: Belongs to the TFIIB family.

284591:YALI0 F04818g
gene id: 284591:YALI0_F04818g
uniprot id: Q6C2V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

284591:YALI0 E16236g
gene id: 284591:YALI0_E16236g
uniprot id: Q6C5Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STE12 transcription factor family.
messages: Nucleus

284591:YALI0 E01056g
gene id: 284591:YALI0_E01056g
uniprot id: F2Z650
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

284591:YALI0 A18722g
gene id: 284591:YALI0_A18722g
uniprot id: F2Z6B2
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

284591:YALI0 A05357g
gene id: 284591:YALI0_A05357g
uniprot id: Q6CHS8
names: Similarity
messages: Belongs to the PPP phosphatase family.

284591:YALI0 F09988g
gene id: 284591:YALI0_F09988g
uniprot id: Q6C283
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

284591:YALI0 F30085g
gene id: 284591:YALI0_F30085g
uniprot id: Q6BZX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BMT2 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA.
messages: nucleolus

284591:YALI0 C04345g
gene id: 284591:YALI0_C04345g
uniprot id: Q6CD25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

284591:YALI0 B03080g
gene id: 284591:YALI0_B03080g
uniprot id: W0TYP4
names: Similarity
messages: Belongs to the FAH family.

284591:YALI0 B01826g
gene id: 284591:YALI0_B01826g
uniprot id: Q6CG11
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the flavokinase family.
messages: Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.
messages: Zinc or magnesium.

284591:YALI0 D11308g
gene id: 284591:YALI0_D11308g
uniprot id: Q6C9G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Cytoplasm

284591:YALI0 A08580g
gene id: 284591:YALI0_A08580g
uniprot id: Q6CHI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAD18 family.
messages: E3 RING-finger protein, member of the UBC2/RAD6 epistasis group. Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA.
messages: Interacts with E2 UBC2, forming a complex with ubiquitin ligase activity.
messages: Nucleus

284591:YALI0 B20020g
gene id: 284591:YALI0_B20020g
uniprot id: Q6CDZ3
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

284591:YALI0 B08184g
gene id: 284591:YALI0_B08184g
uniprot id: Q6CFD2
names: Activity Regulation
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically inhibited by 3'-phosphoadenosine 5'-phosphosulfate (PAPS).
messages: Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
messages: Cytoplasm
messages: Homohexamer. Dimer of trimers.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the sulfate adenylyltransferase family.
messages: The adenylyl-sulfate kinase (APS kinase) is non-functional. It is involved in allosteric regulation by PAPS. PAPS binding induces a large rotational rearrangement of domains lowering the substrate affinity of the enzyme.

284591:YALI0 E18568g
gene id: 284591:YALI0_E18568g
uniprot id: Q05493
names: Disruption Phenotype
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Cells are unable to grow on solid media with oleate as a carbon source.
messages: Homodimer. Interacts (via PTS2-type peroxisomal targeting signal region) with PEX7; leading to its translocation into peroxisomes.
messages: Peroxisome
messages: Responsible for the thiolytic cleavage of straight chain 3-keto fatty acyl-CoAs (3-oxoacyl-CoAs).
messages: The PTS2-type peroxisomal targeting signal, which mediates interaction with PEX7 and localization to peroxisomes, is cleaved following import into peroxisomes.

284591:YALI0 C23166g
gene id: 284591:YALI0_C23166g
uniprot id: Q6CAZ4
names: Subcellular Location Annotation
messages: Nucleus membrane

284591:YALI0 D02805g
gene id: 284591:YALI0_D02805g
uniprot id: Q6CAH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: actin patch

284591:YALI0 B18810g
gene id: 284591:YALI0_B18810g
uniprot id: Q6CE38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: May associate with the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.

284591:YALI0 E05335g
gene id: 284591:YALI0_E05335g
uniprot id: Q6C6Y2
names: Similarity
messages: Belongs to the actin family.

284591:YALI0 A02563g
gene id: 284591:YALI0_A02563g
uniprot id: Q6CI14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

284591:YALI0 D12400g
gene id: 284591:YALI0_D12400g
uniprot id: P29407
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

284591:YALI0 D13112g
gene id: 284591:YALI0_D13112g
uniprot id: Q6C985
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

284591:YALI0 F22136g
gene id: 284591:YALI0_F22136g
uniprot id: Q6C0S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.

284591:YALI0 E00946g
gene id: 284591:YALI0_E00946g
uniprot id: Q6C7G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWC5 family.
messages: Component of the SWR1 chromatin remodeling complex.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability (By similarity).
messages: Nucleus

284591:YALI0 D09603g
gene id: 284591:YALI0_D09603g
uniprot id: Q6C9P0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane
messages: May function both as a monomer and a homodimer.

284591:YALI0 E30635g
gene id: 284591:YALI0_E30635g
uniprot id: Q6C414
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat SEC31 family.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
messages: Endoplasmic reticulum membrane
messages: The COPII coat is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex, and the protein SAR1. SEC13 and SEC31 make a 2:2 tetramer that forms the edge element of the COPII outer coat. The tetramer self-assembles in multiple copies to form the complete polyhedral cage. Interacts (via WD 8) with SEC13 (By similarity).

284591:YALI0 E08030g
gene id: 284591:YALI0_E08030g
uniprot id: Q6C6N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
messages: Homodimer.
messages: Mitochondrion inner membrane
messages: Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating the ATP-dependent export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins (By similarity). Hydrolyzes ATP (By similarity). Binds glutathione and may function by transporting a glutathione-conjugated iron-sulfur compound (By similarity).

284591:YALI0 F23991g
gene id: 284591:YALI0_F23991g
uniprot id: Q6C0K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YPI1 family.
messages: Nucleus
messages: Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.

284591:YALI0 E13530g
gene id: 284591:YALI0_E13530g
uniprot id: Q6C607
names: Similarity
messages: Belongs to the WD repeat LST8 family.

284591:YALI0 B01298g
gene id: 284591:YALI0_B01298g
uniprot id: Q6CG32
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

284591:YALI0 F20042g
gene id: 284591:YALI0_F20042g
uniprot id: Q6C116
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Mitochondrion
messages: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

284591:YALI0 D06325g
gene id: 284591:YALI0_D06325g
uniprot id: Q6CA32
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

284591:YALI0 F23111g
gene id: 284591:YALI0_F23111g
uniprot id: Q6C0N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

284591:YALI0 F17226g
gene id: 284591:YALI0_F17226g
uniprot id: Q6C1D6
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

284591:YALI0 E23694g
gene id: 284591:YALI0_E23694g
uniprot id: Q6C4U1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Part of the 30S ribosomal subunit.

284591:YALI0 B19976g
gene id: 284591:YALI0_B19976g
uniprot id: Q6CDZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284591:YALI0 A05401g
gene id: 284591:YALI0_A05401g
uniprot id: Q6CHS6
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: As accessory component of the DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication.
messages: Heterotetramer. Consists of four subunits: POL2, DPB2, DPB3 and DPB4 (By similarity).
messages: In eukaryotes there are five DNA polymerases: alpha, beta, gamma, delta, and epsilon which are responsible for different reactions of DNA synthesis.
messages: Nucleus

284591:YALI0 A08041g
gene id: 284591:YALI0_A08041g
uniprot id: Q6CHK1
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

284591:YALI0 E30569g
gene id: 284591:YALI0_E30569g
uniprot id: Q6C417
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284591:YALI0 E22913g
gene id: 284591:YALI0_E22913g
uniprot id: Q6C4X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 F16027g
gene id: 284591:YALI0_F16027g
uniprot id: Q6C1I2
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

284591:YALI0 E28963g
gene id: 284591:YALI0_E28963g
uniprot id: Q6C482
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).

284591:YALI0 D14564g
gene id: 284591:YALI0_D14564g
uniprot id: Q6C935
names: Similarity
messages: Belongs to the CIA30 family.

284591:YALI0 E09493g
gene id: 284591:YALI0_E09493g
uniprot id: Q6C6H5
names: Similarity
messages: In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.

284591:YALI0 F15367g
gene id: 284591:YALI0_F15367g
uniprot id: Q6C1K8
names: Similarity
messages: Belongs to the peptidase C19 family.

284591:YALI0 E24519g
gene id: 284591:YALI0_E24519g
uniprot id: Q6C4Q6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated to ATG12; which is essential for autophagy.
messages: Conjugated with ATG12.
messages: Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy). Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).
messages: Preautophagosomal structure membrane

284591:YALI0 B22594g
gene id: 284591:YALI0_B22594g
uniprot id: Q6CDN4
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

284591:YALI0 B13464g
gene id: 284591:YALI0_B13464g
uniprot id: Q6CES1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytoskeleton

284591:YALI0 C21472g
gene id: 284591:YALI0_C21472g
uniprot id: Q6CB69
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in translation initiation. Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes (By similarity).
messages: Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
messages: Cytoplasm
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284591:YALI0 F25839g
gene id: 284591:YALI0_F25839g
uniprot id: Q6C0C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Rnase which modulates cell survival under stress conditions. Released from the vacuole to the cytoplasm during stress to promote tRNA and rRNA cleavage and to activate separately a downstream pathway that promotes cell death. Involved in cell size, vacuolar morphology and growth at high temperatures and high salt concentration.
messages: Vacuole lumen

284591:YALI0 A01001g
gene id: 284591:YALI0_A01001g
uniprot id: Q6CI73
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 B19492g
gene id: 284591:YALI0_B19492g
uniprot id: Q6CE13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

284591:YALI0 F29183g
gene id: 284591:YALI0_F29183g
uniprot id: Q6C003
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C11253g
gene id: 284591:YALI0_C11253g
uniprot id: Q6CC98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284591:YALI0 A12001g
gene id: 284591:YALI0_A12001g
uniprot id: Q6CH64
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

284591:YALI0 E02354g
gene id: 284591:YALI0_E02354g
uniprot id: Q6C7A6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NBP35 and two labile, bridging clusters between subunits of the NBP35-CFD1 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export.
messages: Cytoplasm
messages: Heterotetramer of 2 NBP35 and 2 CFD1 chains.
messages: Nucleus

284591:YALI0 E14773g
gene id: 284591:YALI0_E14773g
uniprot id: Q6C5V7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in cell cycle progression and meiosis (By similarity).
messages: Interacts with H3K4me3 and to a lesser extent with H3K4me2. Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

284591:YALI0 D25212g
gene id: 284591:YALI0_D25212g
uniprot id: Q6C7U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRM44 family.
messages: Cytoplasm
messages: Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.

284591:YALI0 C10472g
gene id: 284591:YALI0_C10472g
uniprot id: Q6CCD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

284591:YALI0 B18612g
gene id: 284591:YALI0_B18612g
uniprot id: Q6CE47
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.

284591:YALI0 D04048g
gene id: 284591:YALI0_D04048g
uniprot id: Q6CAC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHO1 family.
messages: Cell membrane
messages: Forms homooligomers.
messages: Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.

284591:YALI0 F26147g
gene id: 284591:YALI0_F26147g
uniprot id: Q6C0B6
names: Function
messages: May contribute to neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity (By similarity).

284591:YALI0 B00902g
gene id: 284591:YALI0_B00902g
uniprot id: Q6CG48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
messages: Self-associates. Interacts with NDL1 and dynein.
messages: cytoskeleton
messages: spindle pole

284591:YALI0 F25223g
gene id: 284591:YALI0_F25223g
uniprot id: Q6C0F2
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B13618g
gene id: 284591:YALI0_B13618g
uniprot id: Q6CER6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

284591:YALI0 F19228g
gene id: 284591:YALI0_F19228g
uniprot id: Q6C150
names: Similarity
messages: Belongs to the lysophospholipase family.

284591:YALI0 B11594g
gene id: 284591:YALI0_B11594g
uniprot id: Q6CEZ5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

284591:YALI0 A20416g
gene id: 284591:YALI0_A20416g
uniprot id: Q6CGC7
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

284591:YALI0 D01331g
gene id: 284591:YALI0_D01331g
uniprot id: Q6CAN1
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 B08943g
gene id: 284591:YALI0_B08943g
uniprot id: Q6CFA0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284591:YALI0 F12001g
gene id: 284591:YALI0_F12001g
uniprot id: Q6C200
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

284591:YALI0 F02167g
gene id: 284591:YALI0_F02167g
uniprot id: Q6C369
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

284591:YALI0 F02827g
gene id: 284591:YALI0_F02827g
uniprot id: Q6C341
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated once deposited into chromatin.
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. H2A or its variant H2A.Z forms a heterodimer with H2B. H2A.Z associates with the VPS72/SWC2 subunit of the SWR1 chromatin remodeling complex. Interacts also with RBP1/DNA-directed RNA polymerase II largest subunit (By similarity).
messages: Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received. Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins. Required for the RNA polymerase II and SPT15/TBP recruitment to the target genes. Involved in chromosome stability (By similarity).

284591:YALI0 A11099g
gene id: 284591:YALI0_A11099g
uniprot id: Q6CH93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

284591:YALI0 C14410g
gene id: 284591:YALI0_C14410g
uniprot id: Q6CBY6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A10725g
gene id: 284591:YALI0_A10725g
uniprot id: Q6CHA6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS7 family.

284591:YALI0 F15169g
gene id: 284591:YALI0_F15169g
uniprot id: Q6C1L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TEC1 family.
messages: Nucleus

284591:YALI0 F17776g
gene id: 284591:YALI0_F17776g
uniprot id: Q6C1B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 16 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284591:YALI0 F02475g
gene id: 284591:YALI0_F02475g
uniprot id: Q6C355
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

284591:YALI0 A06523g
gene id: 284591:YALI0_A06523g
uniprot id: Q6CHQ1
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

284591:YALI0 E03630g
gene id: 284591:YALI0_E03630g
uniprot id: Q6C755
names: Similarity
messages: Belongs to the RNR ribonuclease family.

284591:YALI0 F06314g
gene id: 284591:YALI0_F06314g
uniprot id: Q6C2N9
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

284591:YALI0 D15400g
gene id: 284591:YALI0_D15400g
uniprot id: Q6C903
names: Cofactor
names: Similarity
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

284591:YALI0 E26983g
gene id: 284591:YALI0_E26983g
uniprot id: Q6C4G5
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D01067g
gene id: 284591:YALI0_D01067g
uniprot id: Q6CAP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IML1 family.
messages: Vacuole membrane

284591:YALI0 F17490g
gene id: 284591:YALI0_F17490g
uniprot id: Q6C1C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRE9/KNH1 family.
messages: Involved in cell wall beta(1->6) glucan synthesis.
messages: cell wall

284591:YALI0 F20328g
gene id: 284591:YALI0_F20328g
uniprot id: Q6C104
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

284591:YALI0 F30877g
gene id: 284591:YALI0_F30877g
uniprot id: Q6BZU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCS1 family.
messages: Binds 2 copper ions per subunit.
messages: Copper chaperone for superoxide dismutase 1 (SOD1). Binds copper ions and delivers them specifically to SOD1 (By similarity).
messages: Cytoplasm

284591:YALI0 E12573g
gene id: 284591:YALI0_E12573g
uniprot id: Q6C643
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

284591:YALI0 F13145g
gene id: 284591:YALI0_F13145g
uniprot id: Q6C1V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

284591:YALI0 E10747g
gene id: 284591:YALI0_E10747g
uniprot id: Q6C6B9
names: Similarity
messages: Belongs to the activator 1 small subunits family.

284591:YALI0 D07480g
gene id: 284591:YALI0_D07480g
uniprot id: Q6C9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPS2 family.
messages: Cell membrane
messages: Membrane

284591:YALI0 E14190g
gene id: 284591:YALI0_E14190g
uniprot id: Q6C5X9
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

284591:YALI0 F19910g
gene id: 284591:YALI0_F19910g
uniprot id: Q6C120
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

284591:YALI0 B08748g
gene id: 284591:YALI0_B08748g
uniprot id: Q6CFB0
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

284591:YALI0 A09878g
gene id: 284591:YALI0_A09878g
uniprot id: Q6CHD9
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

284591:YALI0 D00803g
gene id: 284591:YALI0_D00803g
uniprot id: Q6CAQ5
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

284591:YALI0 D00220g
gene id: 284591:YALI0_D00220g
uniprot id: Q6CAT1
names: Similarity
messages: Belongs to the HscB family.

284591:YALI0 B08470g
gene id: 284591:YALI0_B08470g
uniprot id: Q6CFB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

284591:YALI0 E12276g
gene id: 284591:YALI0_E12276g
uniprot id: B5FVH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

284591:YALI0 F21153g
gene id: 284591:YALI0_F21153g
uniprot id: Q6C0W6
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

284591:YALI0 A17127g
gene id: 284591:YALI0_A17127g
uniprot id: Q6CGR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

284591:YALI0 A06655g
gene id: 284591:YALI0_A06655g
uniprot id: Q6CHP7
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F21263g
gene id: 284591:YALI0_F21263g
uniprot id: Q6C0W1
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 C16225g
gene id: 284591:YALI0_C16225g
uniprot id: Q6CBR6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D15304g
gene id: 284591:YALI0_D15304g
uniprot id: Q6C908
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PAN1 family.
messages: Cell membrane
messages: Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
messages: Component of the PAN1 actin cytoskeleton-regulatory complex.
messages: Endosome membrane
messages: actin patch

284591:YALI0 E09240g
gene id: 284591:YALI0_E09240g
uniprot id: Q6C6I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.

284591:YALI0 C05533g
gene id: 284591:YALI0_C05533g
uniprot id: Q6CCY5
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.

284591:YALI0 D20306g
gene id: 284591:YALI0_D20306g
uniprot id: Q6C8E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCC1 family.
messages: Membrane

284591:YALI0 F24123g
gene id: 284591:YALI0_F24123g
uniprot id: Q6C0J5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

284591:YALI0 D12881g
gene id: 284591:YALI0_D12881g
uniprot id: Q6C997
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.

284591:YALI0 A04367g
gene id: 284591:YALI0_A04367g
uniprot id: P41925
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic (By similarity).

284591:YALI0 C07590g
gene id: 284591:YALI0_C07590g
uniprot id: Q6CCQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

284591:YALI0 C08701g
gene id: 284591:YALI0_C08701g
uniprot id: Q6CCK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ku70 family.
messages: Heterodimer of Ku70 and Ku80.
messages: Nucleus
messages: Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. Involved in telomere maintenance. Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement. Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere. Required for mating-type switching (By similarity).
messages: telomere

284591:YALI0 F24651g
gene id: 284591:YALI0_F24651g
uniprot id: Q6C0H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

284591:YALI0 A15433g
gene id: 284591:YALI0_A15433g
uniprot id: B5RSK1
names: Similarity
messages: Belongs to the complex I LYR family.

284591:YALI0 F01232g
gene id: 284591:YALI0_F01232g
uniprot id: Q6C3A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

284591:YALI0 F22363g
gene id: 284591:YALI0_F22363g
uniprot id: Q6C0R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion inner membrane
messages: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.

284591:YALI0 F26653g
gene id: 284591:YALI0_F26653g
uniprot id: Q6C095
names: Subcellular Location Annotation
messages: nucleolus

284591:YALI0 C12386g
gene id: 284591:YALI0_C12386g
uniprot id: Q6CC54
names: Similarity
messages: Belongs to the protein disulfide isomerase family.

284591:YALI0 A19492g
gene id: 284591:YALI0_A19492g
uniprot id: Q6CGG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 F26279g
gene id: 284591:YALI0_F26279g
uniprot id: Q6C0B2
names: Similarity
messages: Belongs to the pirin family.

284591:YALI0 C07953g
gene id: 284591:YALI0_C07953g
uniprot id: Q6CCN4
names: Similarity
messages: Belongs to the heat shock protein 90 family.

284591:YALI0 A06215g
gene id: 284591:YALI0_A06215g
uniprot id: W0TYQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histone H4 family.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

284591:YALI0 B13816g
gene id: 284591:YALI0_B13816g
uniprot id: F2Z6H3
names: Similarity
messages: Belongs to the cytochrome P450 family.

284591:YALI0 F26807g
gene id: 284591:YALI0_F26807g
uniprot id: Q6C089
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

284591:YALI0 B11528g
gene id: 284591:YALI0_B11528g
uniprot id: Q6CEZ8
names: Similarity
messages: Belongs to the BLOC1S1 family.

284591:YALI0 B16236g
gene id: 284591:YALI0_B16236g
uniprot id: Q6CEE7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endopolyphosphatase PPN1 family.
messages: Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.
messages: Processing by proteases in the vacuole may be required for activation.
messages: Vacuole membrane

284591:YALI0 D12188g
gene id: 284591:YALI0_D12188g
uniprot id: Q6C9D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

284591:YALI0 E23474g
gene id: 284591:YALI0_E23474g
uniprot id: F2Z6D5
names: Similarity
messages: Belongs to the cytochrome P450 family.

284591:YALI0 E27632g
gene id: 284591:YALI0_E27632g
uniprot id: Q6C4D8
names: Similarity
messages: Belongs to the protein kinase superfamily.

284591:YALI0 E32747g
gene id: 284591:YALI0_E32747g
uniprot id: Q6C3R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS41 family.
messages: Involved in telomere length regulation.
messages: Mitochondrion

284591:YALI0 A01331g
gene id: 284591:YALI0_A01331g
uniprot id: Q6CI64
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 F14179g
gene id: 284591:YALI0_F14179g
uniprot id: Q6C1R1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

284591:YALI0 A04983g
gene id: 284591:YALI0_A04983g
uniprot id: Q6CHU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

284591:YALI0 D03575g
gene id: 284591:YALI0_D03575g
uniprot id: Q6CAE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Membrane

284591:YALI0 C10604g
gene id: 284591:YALI0_C10604g
uniprot id: Q6CCC7
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

284591:YALI0 D15708g
gene id: 284591:YALI0_D15708g
uniprot id: Q6C8Y9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

284591:YALI0 B20570g
gene id: 284591:YALI0_B20570g
uniprot id: Q6CDX0
names: Similarity
messages: Belongs to the KNR4/SMI1 family.

284591:YALI0 C07062g
gene id: 284591:YALI0_C07062g
uniprot id: Q6CCR9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

284591:YALI0 F07491g
gene id: 284591:YALI0_F07491g
uniprot id: Q6C2J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
messages: Mitochondrion outer membrane

284591:YALI0 E19943g
gene id: 284591:YALI0_E19943g
uniprot id: Q6C596
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

284591:YALI0 B10296g
gene id: 284591:YALI0_B10296g
uniprot id: Q6CF48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex ASK1 family.
messages: Nucleus
messages: kinetochore
messages: spindle

284591:YALI0 F20658g
gene id: 284591:YALI0_F20658g
uniprot id: Q6C0Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 B12892g
gene id: 284591:YALI0_B12892g
uniprot id: Q6CEU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Involved in the maintenance of ribosomal (rDNA). Required for efficient fork arrest at the replicaion fork barrier within rDNA. Involved in the maintenance of mitochondrial (mtDNA). Required to maintain mtDNA under conditions that introduce dsDNA breaks in mtDNA, either preventing or repairing dsDNA breaks. May inhibit replication progression to allow time for repair. May have a general role in chromosomal replication by affecting Okazaki fragment maturation. May have a role in conjunction with DNA2 helicase/nuclease in 5'-flap extension during Okazaki fragment processing.
messages: Mitochondrion
messages: Monomer. Interacts with telomerase.
messages: Nucleus

284591:YALI0 E22506g
gene id: 284591:YALI0_E22506g
uniprot id: Q6C4Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

284591:YALI0 B16038g
gene id: 284591:YALI0_B16038g
uniprot id: Q6CEF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Cytoplasm
messages: Mevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway. The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.

284591:YALI0 D18722g
gene id: 284591:YALI0_D18722g
uniprot id: Q6C8L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYSTM1 family.
messages: Membrane

284591:YALI0 C07887g
gene id: 284591:YALI0_C07887g
uniprot id: Q6CCN7
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

284591:YALI0 C01287g
gene id: 284591:YALI0_C01287g
uniprot id: Q6CDD9
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

284591:YALI0 E28490g
gene id: 284591:YALI0_E28490g
uniprot id: Q6C4A3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA (By similarity). The NAD-cap is present at the 5'-end of some RNAs and snoRNAs. In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay (By similarity). Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs (By similarity). Has decapping activity toward incomplete 5'-end m7G cap mRNAs such as unmethylated 5'-end-capped RNA (cap0), while it has no activity toward 2'-O-ribose methylated m7G cap (cap1) (By similarity).
messages: Divalent metal cation.
messages: Nucleus

284591:YALI0 F20262g
gene id: 284591:YALI0_F20262g
uniprot id: Q6C107
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
messages: Mitochondrion inner membrane

284591:YALI0 C10032g
gene id: 284591:YALI0_C10032g
uniprot id: Q6CCE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

284591:YALI0 C02431g
gene id: 284591:YALI0_C02431g
uniprot id: Q6CDA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284591:YALI0 D00935g
gene id: 284591:YALI0_D00935g
uniprot id: Q6CAP9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MMM1 family.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM11 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
messages: Endoplasmic reticulum membrane
messages: Homodimer. Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.
messages: The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.

284591:YALI0 E13486g
gene id: 284591:YALI0_E13486g
uniprot id: Q6C609
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

284591:YALI0 E01298g
gene id: 284591:YALI0_E01298g
uniprot id: P80547
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Expressed essentially in cells grown on palmitic acid with small amounts found in cells grown on glucose.
messages: May play a role in the transport of fatty acids. Binds fatty acids and fatty acyl-CoAs including palmitic acid, oleic acid, cis-parinaric acid and palmitoyl-CoA (in vitro).
messages: Monomer.
messages: Peroxisome

284591:YALI0 B21252g
gene id: 284591:YALI0_B21252g
uniprot id: Q6CDT9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

284591:YALI0 E20537g
gene id: 284591:YALI0_E20537g
uniprot id: Q6C571
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 B13750g
gene id: 284591:YALI0_B13750g
uniprot id: Q6CER0
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E33693g
gene id: 284591:YALI0_E33693g
uniprot id: W0TYM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 F10549g
gene id: 284591:YALI0_F10549g
uniprot id: Q6C261
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 C19085g
gene id: 284591:YALI0_C19085g
uniprot id: Q6CBG4
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

284591:YALI0 A08107g
gene id: 284591:YALI0_A08107g
uniprot id: Q6CHJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RTT106 family.
messages: Chromosome
messages: Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity).
messages: Interacts with histones H3 and H4.
messages: Nucleus

284591:YALI0 D23595g
gene id: 284591:YALI0_D23595g
uniprot id: Q6C816
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

284591:YALI0 F32153g
gene id: 284591:YALI0_F32153g
uniprot id: Q6BZP0
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 F03300g
gene id: 284591:YALI0_F03300g
uniprot id: Q6C321
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 D24387g
gene id: 284591:YALI0_D24387g
uniprot id: Q6C7Y3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

284591:YALI0 F13277g
gene id: 284591:YALI0_F13277g
uniprot id: Q6C1U6
names: Similarity
messages: Belongs to the NEMF family.

284591:YALI0 C21087g
gene id: 284591:YALI0_C21087g
uniprot id: Q6CB88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

284591:YALI0 A14586g
gene id: 284591:YALI0_A14586g
uniprot id: Q6CGZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

284591:YALI0 E27137g
gene id: 284591:YALI0_E27137g
uniprot id: Q6C4F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase TRM13 family.
messages: Cytoplasm
messages: nucleolus
messages: tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

284591:YALI0 E08822g
gene id: 284591:YALI0_E08822g
uniprot id: Q6C6K6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

284591:YALI0 F16049g
gene id: 284591:YALI0_F16049g
uniprot id: Q6C1I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

284591:YALI0 B18722g
gene id: 284591:YALI0_B18722g
uniprot id: Q6CE42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Nucleus

284591:YALI0 B20658g
gene id: 284591:YALI0_B20658g
uniprot id: Q6CDW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm

284591:YALI0 D24189g
gene id: 284591:YALI0_D24189g
uniprot id: Q6C7Z1
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A00616g
gene id: 284591:YALI0_A00616g
uniprot id: Q6CI88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Nucleus

284591:YALI0 D04202g
gene id: 284591:YALI0_D04202g
uniprot id: Q6CAB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family. PIGB subfamily.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly (By similarity).

284591:YALI0 E14014g
gene id: 284591:YALI0_E14014g
uniprot id: Q6C5Y7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

284591:YALI0 E32813g
gene id: 284591:YALI0_E32813g
uniprot id: Q6C3R0
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

284591:YALI0 A17380g
gene id: 284591:YALI0_A17380g
uniprot id: Q6CGQ0
names: Subcellular Location Annotation
messages: Cytoplasm

284591:YALI0 F03839g
gene id: 284591:YALI0_F03839g
uniprot id: Q99150
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein).
messages: Cytoplasm
messages: Fungal signal recognition particle consists of a 7S RNA molecule (SCR1) and at least seven protein subunits: SRP72, SRP68, SRP54, SEC65, SRP21, SRP14 and SRP7.
messages: Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.

284591:YALI0 D25322g
gene id: 284591:YALI0_D25322g
uniprot id: Q6C7U3
names: Similarity
messages: Belongs to the NipSnap family.

284591:YALI0 C06039g
gene id: 284591:YALI0_C06039g
uniprot id: Q6CCW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

284591:YALI0 F18700g
gene id: 284591:YALI0_F18700g
uniprot id: Q6C172
names: Function
names: Similarity
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.

284591:YALI0 B04246g
gene id: 284591:YALI0_B04246g
uniprot id: Q6CFS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: coated pit

284591:YALI0 C13354g
gene id: 284591:YALI0_C13354g
uniprot id: Q6CC22
names: Similarity
messages: Belongs to the thymidylate kinase family.

284591:YALI0 D21494g
gene id: 284591:YALI0_D21494g
uniprot id: Q6C898
names: Similarity
messages: Belongs to the ELP6 family.

284591:YALI0 D23243g
gene id: 284591:YALI0_D23243g
uniprot id: Q6C830
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit K family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

284591:YALI0 F09141g
gene id: 284591:YALI0_F09141g
uniprot id: Q6C2B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-Y family.
messages: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
messages: Nucleus

284591:YALI0 C04499g
gene id: 284591:YALI0_C04499g
uniprot id: Q6CD18
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B17710g
gene id: 284591:YALI0_B17710g
uniprot id: Q6CE85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic12 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

284591:YALI0 A19228g
gene id: 284591:YALI0_A19228g
uniprot id: Q6CGH6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

284591:YALI0 E13948g
gene id: 284591:YALI0_E13948g
uniprot id: Q6C5Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

284591:YALI0 A18766g
gene id: 284591:YALI0_A18766g
uniprot id: Q6CGJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRO1 family.
messages: Cytoplasm
messages: Endosome
messages: Involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles.

284591:YALI0 B06710g
gene id: 284591:YALI0_B06710g
uniprot id: Q6CFI5
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E12221g
gene id: 284591:YALI0_E12221g
uniprot id: Q6C658
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

284591:YALI0 D21956g
gene id: 284591:YALI0_D21956g
uniprot id: Q6C880
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Required for transport from the ER to the Golgi complex.

284591:YALI0 C06215g
gene id: 284591:YALI0_C06215g
uniprot id: Q6CCV4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with TAH18. Interacts with MIA40.
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

284591:YALI0 C23859g
gene id: 284591:YALI0_C23859g
uniprot id: F2Z630
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

284591:YALI0 F30063g
gene id: 284591:YALI0_F30063g
uniprot id: Q6BZX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

284591:YALI0 B23386g
gene id: 284591:YALI0_B23386g
uniprot id: Q6CDJ8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for proper protein synthesis within the mitochondrion.
messages: Belongs to the GatF family.
messages: Mitochondrion inner membrane
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

284591:YALI0 C11297g
gene id: 284591:YALI0_C11297g
uniprot id: Q6CC96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

284591:YALI0 F31427g
gene id: 284591:YALI0_F31427g
uniprot id: Q6BZR7
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

284591:YALI0 D06798g
gene id: 284591:YALI0_D06798g
uniprot id: Q6CA10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 B01342g
gene id: 284591:YALI0_B01342g
uniprot id: Q6CG30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 D08690g
gene id: 284591:YALI0_D08690g
uniprot id: Q6C9S7
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

284591:YALI0 E32527g
gene id: 284591:YALI0_E32527g
uniprot id: Q6C3S3
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-II family.

284591:YALI0 C16049g
gene id: 284591:YALI0_C16049g
uniprot id: Q6CBS2
names: Similarity
messages: Belongs to the GST superfamily.

284591:YALI0 E34687g
gene id: 284591:YALI0_E34687g
uniprot id: Q6C3H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

284591:YALI0 D19888g
gene id: 284591:YALI0_D19888g
uniprot id: Q6C8G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

284591:YALI0 E29307g
gene id: 284591:YALI0_E29307g
uniprot id: Q6C467
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-Z subfamily.
messages: Cytoplasm

284591:YALI0 D25938g
gene id: 284591:YALI0_D25938g
uniprot id: Q6C7R6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B00396g
gene id: 284591:YALI0_B00396g
uniprot id: Q6CG69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 C08228g
gene id: 284591:YALI0_C08228g
uniprot id: Q6CCM3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D12606g
gene id: 284591:YALI0_D12606g
uniprot id: Q6C9B0
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

284591:YALI0 E00748g
gene id: 284591:YALI0_E00748g
uniprot id: Q6C7H7
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B05280g
gene id: 284591:YALI0_B05280g
uniprot id: Q6CFN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

284591:YALI0 B17248g
gene id: 284591:YALI0_B17248g
uniprot id: Q6CEA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTC6 family.
messages: May be involved in telomere capping.
messages: Membrane

284591:YALI0 E34287g
gene id: 284591:YALI0_E34287g
uniprot id: F2Z5Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

284591:YALI0 D17050g
gene id: 284591:YALI0_D17050g
uniprot id: Q6C8T9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

284591:YALI0 F18040g
gene id: 284591:YALI0_F18040g
uniprot id: Q6C1A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

284591:YALI0 D10593g
gene id: 284591:YALI0_D10593g
uniprot id: Q6C9K0
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

284591:YALI0 B06006g
gene id: 284591:YALI0_B06006g
uniprot id: Q6CFK9
names: Similarity
messages: Belongs to the pantothenate synthetase family.

284591:YALI0 E03872g
gene id: 284591:YALI0_E03872g
uniprot id: Q6C745
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D13104g
gene id: 284591:YALI0_D13104g
uniprot id: Q6C986
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

284591:YALI0 A16698g
gene id: 284591:YALI0_A16698g
uniprot id: Q6CGS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

284591:YALI0 E19184g
gene id: 284591:YALI0_E19184g
uniprot id: Q6C5C7
names: Similarity
messages: Belongs to the peptidase M24B family.

284591:YALI0 F26037g
gene id: 284591:YALI0_F26037g
uniprot id: Q6C0C1
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

284591:YALI0 C15070g
gene id: 284591:YALI0_C15070g
uniprot id: Q6CBW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NST1 family.
messages: Cytoplasm
messages: May act as a negative regulator of salt tolerance.

284591:YALI0 E31361g
gene id: 284591:YALI0_E31361g
uniprot id: Q6C3Y0
names: Similarity
messages: Belongs to the protein kinase superfamily.

284591:YALI0 C07524g
gene id: 284591:YALI0_C07524g
uniprot id: Q6CCQ3
names: Similarity
messages: Belongs to the SUI1 family.

284591:YALI0 C04906g
gene id: 284591:YALI0_C04906g
uniprot id: Q6CD06
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

284591:YALI0 B00572g
gene id: 284591:YALI0_B00572g
uniprot id: Q6CG63
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

284591:YALI0 D10571g
gene id: 284591:YALI0_D10571g
uniprot id: Q6C9K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

284591:YALI0 E22605g
gene id: 284591:YALI0_E22605g
uniprot id: Q6C4Y9
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

284591:YALI0 E01914g
gene id: 284591:YALI0_E01914g
uniprot id: Q6C7C6
names: Subcellular Location Annotation
names: Subunit
messages: Component of the mitochondrial large ribosomal subunit.
messages: Mitochondrion

284591:YALI0 E32769g
gene id: 284591:YALI0_E32769g
uniprot id: Q6C3R2
names: Similarity
messages: Belongs to the diacylglycerol acyltransferase family.

284591:YALI0 E34573g
gene id: 284591:YALI0_E34573g
uniprot id: Q6C3I3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

284591:YALI0 B11308g
gene id: 284591:YALI0_B11308g
uniprot id: Q6CF08
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

284591:YALI0 F02035g
gene id: 284591:YALI0_F02035g
uniprot id: Q6C375
names: Similarity
messages: Belongs to the sorting nexin family.

284591:YALI0 F14663g
gene id: 284591:YALI0_F14663g
uniprot id: Q6C1N9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS30 family.

284591:YALI0 B15290g
gene id: 284591:YALI0_B15290g
uniprot id: Q6CEI9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PROPPIN family.
messages: Cytoplasmic vesicle membrane
messages: Involved in mitochondrial or peroxisomal functions and amino acid signaling pathways.
messages: May contain a beta-propeller domain involved in specific binding to phosphatidylinositol 3,5-bisphosphate (PIP2), leading to the association of the protein to the membrane.
messages: Vacuole membrane

284591:YALI0 B22550g
gene id: 284591:YALI0_B22550g
uniprot id: Q6CDN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

284591:YALI0 E05203g
gene id: 284591:YALI0_E05203g
uniprot id: Q6C6Y8
names: Similarity
messages: Belongs to the glycosyl hydrolase 15 family.

284591:YALI0 B02178g
gene id: 284591:YALI0_B02178g
uniprot id: Q6CFZ7
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

284591:YALI0 A18227g
gene id: 284591:YALI0_A18227g
uniprot id: Q6CGL9
names: Similarity
messages: Belongs to the MAPRE family.

284591:YALI0 C02871g
gene id: 284591:YALI0_C02871g
uniprot id: Q6CD86
names: Similarity
messages: Belongs to the complex I LYR family. SDHAF1 subfamily.

284591:YALI0 E02706g
gene id: 284591:YALI0_E02706g
uniprot id: Q6C792
names: Similarity
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.

284591:YALI0 F00484g
gene id: 284591:YALI0_F00484g
uniprot id: Q6C3E1
names: Similarity
messages: Belongs to the FGGY kinase family.

284591:YALI0 C15356g
gene id: 284591:YALI0_C15356g
uniprot id: Q6CBU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

284591:YALI0 E09933g
gene id: 284591:YALI0_E09933g
uniprot id: Q6C6F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

284591:YALI0 E32351g
gene id: 284591:YALI0_E32351g
uniprot id: Q6C3T1
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

284591:YALI0 C23991g
gene id: 284591:YALI0_C23991g
uniprot id: Q6CAV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Cytoplasm
messages: Rnase which modulates cell survival under stress conditions. Released from the vacuole to the cytoplasm during stress to promote tRNA and rRNA cleavage and to activate separately a downstream pathway that promotes cell death. Involved in cell size, vacuolar morphology and growth at high temperatures and high salt concentration (By similarity).
messages: Vacuole lumen

284591:YALI0 E00726g
gene id: 284591:YALI0_E00726g
uniprot id: Q6C7H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

284591:YALI0 E13926g
gene id: 284591:YALI0_E13926g
uniprot id: Q6C5Z1
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

284591:YALI0 F09856g
gene id: 284591:YALI0_F09856g
uniprot id: Q6C287
names: Subcellular Location Annotation
messages: nucleolus

284591:YALI0 B00990g
gene id: 284591:YALI0_B00990g
uniprot id: Q6CG44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

284591:YALI0 F13783g
gene id: 284591:YALI0_F13783g
uniprot id: Q6C1S4
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

284591:YALI0 F20020g
gene id: 284591:YALI0_F20020g
uniprot id: Q6C117
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 E04169g
gene id: 284591:YALI0_E04169g
uniprot id: B5FVH1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

284591:YALI0 B22682g
gene id: 284591:YALI0_B22682g
uniprot id: Q6CDN0
names: Similarity
messages: Belongs to the VAC14 family.

284591:YALI0 A19448g
gene id: 284591:YALI0_A19448g
uniprot id: Q6CGH0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

284591:YALI0 B17314g
gene id: 284591:YALI0_B17314g
uniprot id: Q6CEA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP11 family.
messages: Mitochondrion

284591:YALI0 F02145g
gene id: 284591:YALI0_F02145g
uniprot id: Q6C370
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the END3 family.
messages: Cell membrane
messages: Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
messages: Component of the PAN1 actin cytoskeleton-regulatory complex.
messages: Endosome membrane
messages: actin patch

284591:YALI0 D05697g
gene id: 284591:YALI0_D05697g
uniprot id: B5FVE0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

284591:YALI0 A16775g
gene id: 284591:YALI0_A16775g
uniprot id: Q6CGS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.
messages: Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.
messages: Cytoplasm
messages: P-body

284591:YALI0 E10571g
gene id: 284591:YALI0_E10571g
uniprot id: Q6C6C6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

284591:YALI0 A17149g
gene id: 284591:YALI0_A17149g
uniprot id: Q6CGR1
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E18612g
gene id: 284591:YALI0_E18612g
uniprot id: Q6C5F1
names: Similarity
messages: Belongs to the UPF0507 family.

284591:YALI0 B11396g
gene id: 284591:YALI0_B11396g
uniprot id: Q6CF04
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

284591:YALI0 E15730g
gene id: 284591:YALI0_E15730g
uniprot id: Q6C5R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

284591:YALI0 C08569g
gene id: 284591:YALI0_C08569g
uniprot id: Q6CCK8
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F01144g
gene id: 284591:YALI0_F01144g
uniprot id: Q8WZL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284591:YALI0 D03333g
gene id: 284591:YALI0_D03333g
uniprot id: Q6CAF2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

284591:YALI0 E26565g
gene id: 284591:YALI0_E26565g
uniprot id: Q6C4I2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

284591:YALI0 F24783g
gene id: 284591:YALI0_F24783g
uniprot id: Q6C0G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Nucleus

284591:YALI0 F04147g
gene id: 284591:YALI0_F04147g
uniprot id: Q6C2Y1
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

284591:YALI0 F24761g
gene id: 284591:YALI0_F24761g
uniprot id: Q6C0H0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D17086g
gene id: 284591:YALI0_D17086g
uniprot id: Q6C8T7
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

284591:YALI0 F26411g
gene id: 284591:YALI0_F26411g
uniprot id: Q6C0A6
names: Similarity
messages: Belongs to the peptidase M67A family.

284591:YALI0 E02552g
gene id: 284591:YALI0_E02552g
uniprot id: Q6C799
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity).
messages: Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284591:YALI0 E12859g
gene id: 284591:YALI0_E12859g
uniprot id: Q6C634
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

284591:YALI0 E34309g
gene id: 284591:YALI0_E34309g
uniprot id: F2Z620
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

284591:YALI0 F27357g
gene id: 284591:YALI0_F27357g
uniprot id: Q6C069
names: Function
names: Similarity
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.

284591:YALI0 E15642g
gene id: 284591:YALI0_E15642g
uniprot id: Q6C5S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: Nucleus

284591:YALI0 D06908g
gene id: 284591:YALI0_D06908g
uniprot id: Q6CA05
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

284591:YALI0 E05027g
gene id: 284591:YALI0_E05027g
uniprot id: Q6C6Z6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

284591:YALI0 B18986g
gene id: 284591:YALI0_B18986g
uniprot id: Q6CE31
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D05841g
gene id: 284591:YALI0_D05841g
uniprot id: Q6CA51
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F27467g
gene id: 284591:YALI0_F27467g
uniprot id: Q6C064
names: Similarity
messages: Belongs to the Luc7 family.

284591:YALI0 D09977g
gene id: 284591:YALI0_D09977g
uniprot id: Q6C9M3
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

284591:YALI0 E17105g
gene id: 284591:YALI0_E17105g
uniprot id: Q6C5L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

284591:YALI0 C01617g
gene id: 284591:YALI0_C01617g
uniprot id: Q6CDC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family.
messages: Cell membrane
messages: Vacuole membrane

284591:YALI0 E04202g
gene id: 284591:YALI0_E04202g
uniprot id: Q6C732
names: Similarity
messages: Belongs to the arginase family.

284591:YALI0 F05324g
gene id: 284591:YALI0_F05324g
uniprot id: Q6C2T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: The COPII coat is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex, and the protein SAR1. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.

284591:YALI0 D03762g
gene id: 284591:YALI0_D03762g
uniprot id: Q6CAD4
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

284591:YALI0 D23815g
gene id: 284591:YALI0_D23815g
uniprot id: Q6C806
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

284591:YALI0 C23122g
gene id: 284591:YALI0_C23122g
uniprot id: Q6CAZ6
names: Similarity
messages: Belongs to the FAH family.

284591:YALI0 D27082g
gene id: 284591:YALI0_D27082g
uniprot id: Q6C7L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an assembly factor of mitochondrial complex I.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Mitochondrion

284591:YALI0 E32065g
gene id: 284591:YALI0_E32065g
uniprot id: Q6C3U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG2 family.
messages: Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.
messages: Endoplasmic reticulum membrane

284591:YALI0 F05478g
gene id: 284591:YALI0_F05478g
uniprot id: Q6C2S8
names: Similarity
messages: Belongs to the APC5 family.

284591:YALI0 C20427g
gene id: 284591:YALI0_C20427g
uniprot id: Q6CBB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
messages: Cytoplasm

284591:YALI0 F28699g
gene id: 284591:YALI0_F28699g
uniprot id: Q6C010
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPC1 family.
messages: Membrane

284591:YALI0 E31471g
gene id: 284591:YALI0_E31471g
uniprot id: Q6C3X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

284591:YALI0 B12474g
gene id: 284591:YALI0_B12474g
uniprot id: Q6CEW0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

284591:YALI0 B10043g
gene id: 284591:YALI0_B10043g
uniprot id: Q6CF60
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
messages: Lacks the C- and N-terminal parts of classical GPI inositol-deacylases and may not have GPI inositol-deacylase activity.

284591:YALI0 E06457g
gene id: 284591:YALI0_E06457g
uniprot id: Q6C6T5
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the activation of alpha-aminoadipate by ATP-dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH. The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate.

284591:YALI0 C21560g
gene id: 284591:YALI0_C21560g
uniprot id: Q6CB65
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

284591:YALI0 E04158g
gene id: 284591:YALI0_E04158g
uniprot id: W0TYM0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B09009g
gene id: 284591:YALI0_B09009g
uniprot id: Q6CF97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

284591:YALI0 D21530g
gene id: 284591:YALI0_D21530g
uniprot id: Q6C897
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

284591:YALI0 A05379g
gene id: 284591:YALI0_A05379g
uniprot id: Q6CHS7
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

284591:YALI0 F08349g
gene id: 284591:YALI0_F08349g
uniprot id: Q6C2F5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG9 family.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Forms a homotrimer with a solvated central pore, which is connected laterally to the cytosol through the cavity within each protomer. Acts as a lipid scramblase that uses its central pore to function: the central pore opens laterally to accommodate lipid headgroups, thereby enabling lipid flipping and redistribution of lipids added to the outer leaflet of ATG9-containing vesicles, thereby enabling growth into autophagosomes.
messages: Golgi apparatus membrane
messages: Homotrimer; forms a homotrimer with a central pore that forms a path between the two membrane leaflets.
messages: Phospholipid scramblase involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion. Required for mitophagy. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.
messages: Phosphorylated by ATG1. ATG1 phosphorylation is required for preautophagosome elongation.
messages: Preautophagosomal structure membrane

284591:YALI0 F31009g
gene id: 284591:YALI0_F31009g
uniprot id: Q6BZT6
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

284591:YALI0 B02728g
gene id: 284591:YALI0_B02728g
uniprot id: Q6CFX7
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

284591:YALI0 B15304g
gene id: 284591:YALI0_B15304g
uniprot id: Q6CEI8
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

284591:YALI0 D05753g
gene id: 284591:YALI0_D05753g
uniprot id: Q6CA55
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

284591:YALI0 F02871g
gene id: 284591:YALI0_F02871g
uniprot id: Q6C339
names: Similarity
messages: Belongs to the OPA3 family.

284591:YALI0 A00913g
gene id: 284591:YALI0_A00913g
uniprot id: Q6CI77
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

284591:YALI0 B02852g
gene id: 284591:YALI0_B02852g
uniprot id: Q6CFX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm

284591:YALI0 D12166g
gene id: 284591:YALI0_D12166g
uniprot id: Q6C9D1
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E33473g
gene id: 284591:YALI0_E33473g
uniprot id: Q6C3N0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D14498g
gene id: 284591:YALI0_D14498g
uniprot id: Q6C938
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Probably involved in transport through the plasma membrane.

284591:YALI0 B08118g
gene id: 284591:YALI0_B08118g
uniprot id: Q6CFD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM34 family.
messages: Mitochondrion membrane

284591:YALI0 F05698g
gene id: 284591:YALI0_F05698g
uniprot id: Q6C2R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Cytoplasm
messages: Nucleus
messages: Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein RAD18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats. Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs (By similarity).

284591:YALI0 D21384g
gene id: 284591:YALI0_D21384g
uniprot id: Q6C8A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Involved in ds DNA break repair. Has a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologous end-joining.
messages: Nucleus

284591:YALI0 F19470g
gene id: 284591:YALI0_F19470g
uniprot id: Q6C140
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

284591:YALI0 E03828g
gene id: 284591:YALI0_E03828g
uniprot id: Q6C747
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.

284591:YALI0 C11693g
gene id: 284591:YALI0_C11693g
uniprot id: Q6CC78
names: Similarity
messages: Belongs to the OSBP family.

284591:YALI0 B00308g
gene id: 284591:YALI0_B00308g
uniprot id: Q6CG71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.

284591:YALI0 C24101g
gene id: 284591:YALI0_C24101g
uniprot id: Q6CAV2
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
messages: Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

284591:YALI0 B15752g
gene id: 284591:YALI0_B15752g
uniprot id: Q6CEG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

284591:YALI0 C11385g
gene id: 284591:YALI0_C11385g
uniprot id: Q6C0C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

284591:YALI0 E10857g
gene id: 284591:YALI0_E10857g
uniprot id: Q6C6B4
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

284591:YALI0 E31551g
gene id: 284591:YALI0_E31551g
uniprot id: Q6C3X1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

284591:YALI0 F20702g
gene id: 284591:YALI0_F20702g
uniprot id: Q6C0Y7
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

284591:YALI0 E01254g
gene id: 284591:YALI0_E01254g
uniprot id: Q6C7F4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

284591:YALI0 F04103g
gene id: 284591:YALI0_F04103g
uniprot id: Q6C2Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 B08536g
gene id: 284591:YALI0_B08536g
uniprot id: Q6CFB6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

284591:YALI0 C01485g
gene id: 284591:YALI0_C01485g
uniprot id: Q6CDD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Alpha-1,2-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers a fourth mannose to trimannosyl-GPIs during GPI precursor assembly. The presence of a fourth mannose in GPI is essential in fungi (By similarity).
messages: Belongs to the glycosyltransferase 22 family. PIGZ subfamily.
messages: Endoplasmic reticulum membrane

284591:YALI0 C12012g
gene id: 284591:YALI0_C12012g
uniprot id: Q6CC68
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F29975g
gene id: 284591:YALI0_F29975g
uniprot id: Q6BZY3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284591:YALI0 F27907g
gene id: 284591:YALI0_F27907g
uniprot id: Q6C044
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PROPPIN family.
messages: Component of the PI(3,5)P2 regulatory complex.
messages: Endosome membrane
messages: Preautophagosomal structure membrane
messages: The L/FRRG motif is essential for the cytoplasm to vacuole transport (Cvt) pathway, for the recruitment of ATG8 and ATG16 to the PAS in nutrient-rich medium, and for its recruitment to and dissociation from the PAS under starvation conditions.
messages: The N-terminus might form a beta-propeller domain involved in specific binding to phosphatidylinositol 3,5-bisphosphate (PIP2), leading to the association of the protein to the membrane.
messages: The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct ATG9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity).
messages: Vacuole membrane

284591:YALI0 F19998g
gene id: 284591:YALI0_F19998g
uniprot id: Q6C118
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

284591:YALI0 C21604g
gene id: 284591:YALI0_C21604g
uniprot id: Q6CB63
names: Similarity
messages: Belongs to the peptidase S10 family.

284591:YALI0 D17556g
gene id: 284591:YALI0_D17556g
uniprot id: Q6C8R7
names: Similarity
messages: Belongs to the UPP synthase family.

284591:YALI0 D25762g
gene id: 284591:YALI0_D25762g
uniprot id: Q6C7S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

284591:YALI0 A21263g
gene id: 284591:YALI0_A21263g
uniprot id: Q6CG88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
messages: Mitochondrion membrane

284591:YALI0 E23089g
gene id: 284591:YALI0_E23089g
uniprot id: Q6C4W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Mitochondrion inner membrane

284591:YALI0 D01199g
gene id: 284591:YALI0_D01199g
uniprot id: Q6CAN7
names: Similarity
messages: Belongs to the Mo25 family.

284591:YALI0 F31031g
gene id: 284591:YALI0_F31031g
uniprot id: Q6BZT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of a pre-mRNA cleavage factor complex. Interacts directly with PCF11.
messages: May lack the polyribonucleotide 5'-hydroxyl-kinase and polynucleotide 5'-hydroxyl-kinase activities that are characteristic of the human ortholog.
messages: Nucleus
messages: Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.

284591:YALI0 E11341g
gene id: 284591:YALI0_E11341g
uniprot id: Q6C697
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

284591:YALI0 D19646g
gene id: 284591:YALI0_D19646g
uniprot id: Q6C8H1
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D27104g
gene id: 284591:YALI0_D27104g
uniprot id: Q6C7L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YPT35 family.
messages: Endosome membrane
messages: Recruits the lipid transfer protein VPS13 to endosomal and vacuolar membranes.
messages: Vacuole membrane

284591:YALI0 E20691g
gene id: 284591:YALI0_E20691g
uniprot id: Q6C564
names: Function
names: Similarity
messages: Belongs to the dihydroxyacetone kinase (DAK) family.
messages: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.

284591:YALI0 C13618g
gene id: 284591:YALI0_C13618g
uniprot id: Q6CC11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: Nucleus
messages: Responsible for methylating the 5'-cap structure of mRNAs.

284591:YALI0 C18073g
gene id: 284591:YALI0_C18073g
uniprot id: Q6CBK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

284591:YALI0 A18469g
gene id: 284591:YALI0_A18469g
uniprot id: Q99160
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E08617g
gene id: 284591:YALI0_E08617g
uniprot id: Q6C6K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

284591:YALI0 D23287g
gene id: 284591:YALI0_D23287g
uniprot id: Q6C828
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 C04818g
gene id: 284591:YALI0_C04818g
uniprot id: Q6CD08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

284591:YALI0 D23683g
gene id: 284591:YALI0_D23683g
uniprot id: Q6C812
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

284591:YALI0 C08782g
gene id: 284591:YALI0_C08782g
uniprot id: Q6CCJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: cis-Golgi network

284591:YALI0 F15191g
gene id: 284591:YALI0_F15191g
uniprot id: Q6C1L5
names: Similarity
messages: Belongs to the SELO family.

284591:YALI0 F00792g
gene id: 284591:YALI0_F00792g
uniprot id: Q6C3C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LU7TM family.
messages: Membrane

284591:YALI0 C06776g
gene id: 284591:YALI0_C06776g
uniprot id: Q6CCT2
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.

284591:YALI0 D17886g
gene id: 284591:YALI0_D17886g
uniprot id: Q6C8Q2
names: Subcellular Location Annotation
messages: nuclear pore complex

284591:YALI0 F07975g
gene id: 284591:YALI0_F07975g
uniprot id: Q6C2G9
names: Similarity
messages: Belongs to the MTFP1 family.

284591:YALI0 D12122g
gene id: 284591:YALI0_D12122g
uniprot id: Q6C9D3
names: Similarity
messages: Belongs to the cytochrome b5 family.

284591:YALI0 E16434g
gene id: 284591:YALI0_E16434g
uniprot id: Q6C5P1
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F21527g
gene id: 284591:YALI0_F21527g
uniprot id: P41923
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

284591:YALI0 F30019g
gene id: 284591:YALI0_F30019g
uniprot id: Q6BZY1
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

284591:YALI0 C22858g
gene id: 284591:YALI0_C22858g
uniprot id: Q6CB07
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E02288g
gene id: 284591:YALI0_E02288g
uniprot id: Q6C7A9
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.

284591:YALI0 E24365g
gene id: 284591:YALI0_E24365g
uniprot id: Q6C4R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FYV7 family.
messages: Involved in the processing of the 20S pre-rRNA.
messages: nucleolus

284591:YALI0 B14509g
gene id: 284591:YALI0_B14509g
uniprot id: Q6CEM5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

284591:YALI0 D03480g
gene id: 284591:YALI0_D03480g
uniprot id: Q6CAE7
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit. Interacts with pstB2. This interaction may be a means to structurally tether the donor membrane (ER) harboring PstB2 to acceptor membranes (Golgi/endosomes) harboring PSD2 during PtdSer transport to the site of PtdEtn synthesis.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: The C2 domains have an essential, but non-catalytic function. They may facilitate interaction with PstB2 and are required for lipid transport function.

284591:YALI0 B01364g
gene id: 284591:YALI0_B01364g
uniprot id: Q6CG29
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

284591:YALI0 B10318g
gene id: 284591:YALI0_B10318g
uniprot id: Q6CF47
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

284591:YALI0 E09196g
gene id: 284591:YALI0_E09196g
uniprot id: Q6C6I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.
messages: Nucleus

284591:YALI0 F02453g
gene id: 284591:YALI0_F02453g
uniprot id: Q6C356
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

284591:YALI0 B10912g
gene id: 284591:YALI0_B10912g
uniprot id: Q6CF24
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YAF9 family.
messages: Component of the SWR1 chromatin-remodeling complex and of the NuA4 histone acetyltransferase complex.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised (By similarity).
messages: Cytoplasm
messages: Nucleus
messages: The coiled-coil domain is required for assembly into the NuA4 complex.

284591:YALI0 E31955g
gene id: 284591:YALI0_E31955g
uniprot id: Q6C3V0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

284591:YALI0 E22759g
gene id: 284591:YALI0_E22759g
uniprot id: Q6C4Y3
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

284591:YALI0 F30283g
gene id: 284591:YALI0_F30283g
uniprot id: Q6BZW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane
messages: Regulates also the sphingolipid metabolism.

284591:YALI0 A09845g
gene id: 284591:YALI0_A09845g
uniprot id: B5RSJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

284591:YALI0 E28622g
gene id: 284591:YALI0_E28622g
uniprot id: Q6C496
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

284591:YALI0 A14762g
gene id: 284591:YALI0_A14762g
uniprot id: Q6CGZ1
names: Similarity
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.

284591:YALI0 F11957g
gene id: 284591:YALI0_F11957g
uniprot id: Q6C202
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with the flavoprotein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

284591:YALI0 C20295g
gene id: 284591:YALI0_C20295g
uniprot id: Q6CBB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

284591:YALI0 F02123g
gene id: 284591:YALI0_F02123g
uniprot id: F2Z6D7
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.

284591:YALI0 D04158g
gene id: 284591:YALI0_D04158g
uniprot id: Q6CAC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

284591:YALI0 F02189g
gene id: 284591:YALI0_F02189g
uniprot id: Q6C368
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

284591:YALI0 D10835g
gene id: 284591:YALI0_D10835g
uniprot id: Q6C9J0
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 F17380g
gene id: 284591:YALI0_F17380g
uniprot id: Q6C1C9
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

284591:YALI0 F13739g
gene id: 284591:YALI0_F13739g
uniprot id: Q6C1S6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C12859g
gene id: 284591:YALI0_C12859g
uniprot id: Q6CC36
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

284591:YALI0 E01232g
gene id: 284591:YALI0_E01232g
uniprot id: Q6C7F5
names: Similarity
messages: Belongs to the WAPL family.

284591:YALI0 B17886g
gene id: 284591:YALI0_B17886g
uniprot id: Q6CE77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role (via N-terminus) in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. Further stabilizes spliceosome conformation for 3'-splice site docking (via C-terminus) promoting exon ligation.

284591:YALI0 F13354g
gene id: 284591:YALI0_F13354g
uniprot id: B5RSL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Nucleus
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.
messages: centromere

284591:YALI0 D11462g
gene id: 284591:YALI0_D11462g
uniprot id: Q6C9G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AATF family.
messages: nucleolus

284591:YALI0 C18535g
gene id: 284591:YALI0_C18535g
uniprot id: Q6CBI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

284591:YALI0 D25366g
gene id: 284591:YALI0_D25366g
uniprot id: Q6C7U1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

284591:YALI0 F23639g
gene id: 284591:YALI0_F23639g
uniprot id: Q6C0L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
messages: Belongs to the ATG17 family.
messages: Cytoplasm
messages: Preautophagosomal structure membrane

284591:YALI0 F28215g
gene id: 284591:YALI0_F28215g
uniprot id: Q6C030
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As accessory component of the DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication.
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Heterotetramer. Consists of four subunits: POL2, DPB2, DPB3 and DPB4 (By similarity).
messages: In eukaryotes there are five DNA polymerases: alpha, beta, gamma, delta, and epsilon which are responsible for different reactions of DNA synthesis.
messages: Nucleus

284591:YALI0 C06886g
gene id: 284591:YALI0_C06886g
uniprot id: Q6CCS7
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

284591:YALI0 B19470g
gene id: 284591:YALI0_B19470g
uniprot id: Q6CE14
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284591:YALI0 E13684g
gene id: 284591:YALI0_E13684g
uniprot id: Q6C600
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAD2 family.
messages: Nucleus

284591:YALI0 F15697g
gene id: 284591:YALI0_F15697g
uniprot id: Q6C1J7
names: Similarity
messages: Belongs to the peptidase C12 family.

284591:YALI0 A20746g
gene id: 284591:YALI0_A20746g
uniprot id: Q6CGB1
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

284591:YALI0 D25168g
gene id: 284591:YALI0_D25168g
uniprot id: Q6C7U9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

284591:YALI0 B11176g
gene id: 284591:YALI0_B11176g
uniprot id: Q6CF14
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

284591:YALI0 D22352g
gene id: 284591:YALI0_D22352g
uniprot id: Q6C864
names: Similarity
messages: Belongs to the heat shock protein 70 family.

284591:YALI0 D26315g
gene id: 284591:YALI0_D26315g
uniprot id: F2Z640
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E01122g
gene id: 284591:YALI0_E01122g
uniprot id: Q6C7G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNO1 family.
messages: Component of the small ribosomal subunit, ribosomal RNA processing complex (SSU RRP complex).
messages: Cytoplasm
messages: Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species (By similarity).
messages: nucleolus

284591:YALI0 C20449g
gene id: 284591:YALI0_C20449g
uniprot id: Q6CBA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Binds 1 AMP per subunit.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

284591:YALI0 C13310g
gene id: 284591:YALI0_C13310g
uniprot id: Q6CC24
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

284591:YALI0 C18051g
gene id: 284591:YALI0_C18051g
uniprot id: Q6CBK3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F29689g
gene id: 284591:YALI0_F29689g
uniprot id: Q6BZZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG12 family.
messages: Forms a conjugate with ATG5.
messages: Preautophagosomal structure membrane
messages: Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate functions as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).

284591:YALI0 E00638g
gene id: 284591:YALI0_E00638g
uniprot id: Q6C7I2
names: Similarity
messages: Belongs to the citrate synthase family.

284591:YALI0 F10703g
gene id: 284591:YALI0_F10703g
uniprot id: Q6C256
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B21846g
gene id: 284591:YALI0_B21846g
uniprot id: Q6CDR5
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

284591:YALI0 E03982g
gene id: 284591:YALI0_E03982g
uniprot id: Q6C740
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFT1 family.
messages: Nucleus
messages: RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Involved in poly(A) site recognition. May be involved in coupling transcription termination and mRNA 3'-end formation (By similarity).

284591:YALI0 E34111g
gene id: 284591:YALI0_E34111g
uniprot id: Q6C3K3
names: Function
names: Similarity
messages: Belongs to the calmodulin family.
messages: May be involved in calcium-mediated signal transduction.

284591:YALI0 B04884g
gene id: 284591:YALI0_B04884g
uniprot id: Q6CFQ2
names: Similarity
messages: Belongs to the pirin family.

284591:YALI0 D17160g
gene id: 284591:YALI0_D17160g
uniprot id: Q6C8T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM9 family.
messages: Mitochondrion

284591:YALI0 A01602g
gene id: 284591:YALI0_A01602g
uniprot id: W0TYQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC6 subfamily.
messages: Chromosome
messages: Nucleus

284591:YALI0 F08613g
gene id: 284591:YALI0_F08613g
uniprot id: Q6C2E3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with cytochrome c oxidase (complex IV, CIV).
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Does not seem to have protease activity as it lacks the zinc-binding site.
messages: Mitochondrion inner membrane

284591:YALI0 A16291g
gene id: 284591:YALI0_A16291g
uniprot id: Q6CGT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YSP2 family.
messages: Membrane

284591:YALI0 E06039g
gene id: 284591:YALI0_E06039g
uniprot id: Q6C6V0
names: Similarity
messages: Belongs to the RNase PH family.

284591:YALI0 C20053g
gene id: 284591:YALI0_C20053g
uniprot id: Q6CBC6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C24167g
gene id: 284591:YALI0_C24167g
uniprot id: Q6CAU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284591:YALI0 E19360g
gene id: 284591:YALI0_E19360g
uniprot id: Q6C5C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

284591:YALI0 D06259g
gene id: 284591:YALI0_D06259g
uniprot id: Q6CA35
names: Similarity
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer.

284591:YALI0 F06908g
gene id: 284591:YALI0_F06908g
uniprot id: Q6C2L1
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D10263g
gene id: 284591:YALI0_D10263g
uniprot id: Q6C9L1
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

284591:YALI0 F22367g
gene id: 284591:YALI0_F22367g
uniprot id: Q6C0R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM11 family.
messages: Membrane

284591:YALI0 E23793g
gene id: 284591:YALI0_E23793g
uniprot id: B5FVF4
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

284591:YALI0 E02827g
gene id: 284591:YALI0_E02827g
uniprot id: P0C0R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERF4 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with ERF2.
messages: The ERF2-ERF4 complex is a palmitoyltransferase specific for Ras proteins. Palmitoylates RAS2, which is required for its proper plasma membrane localization (By similarity).

284591:YALI0 E06215g
gene id: 284591:YALI0_E06215g
uniprot id: Q6C6U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 E19679g
gene id: 284591:YALI0_E19679g
uniprot id: Q6C5A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

284591:YALI0 D22308g
gene id: 284591:YALI0_D22308g
uniprot id: Q6C866
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

284591:YALI0 F15477g
gene id: 284591:YALI0_F15477g
uniprot id: Q6C1K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Required both for recombination and for the repair of DNA damage caused by X-rays.

284591:YALI0 E31405g
gene id: 284591:YALI0_E31405g
uniprot id: Q6C3X8
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C07282g
gene id: 284591:YALI0_C07282g
uniprot id: Q6CCR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG29 family.
messages: Preautophagosomal structure

284591:YALI0 E23045g
gene id: 284591:YALI0_E23045g
uniprot id: Q6C4X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCO1/2 family.
messages: Mitochondrion inner membrane

284591:YALI0 B10219g
gene id: 284591:YALI0_B10219g
uniprot id: Q6CF52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

284591:YALI0 B03300g
gene id: 284591:YALI0_B03300g
uniprot id: Q6CFV7
names: Subcellular Location Annotation
messages: Cytoplasm

284591:YALI0 E12287g
gene id: 284591:YALI0_E12287g
uniprot id: Q6C656
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSM3 family.
messages: Component of the fork protection complex (FPC) consisting of TOF1 and CSM3.
messages: Forms a fork protection complex (FPC) with TOF1 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity).
messages: Nucleus

284591:YALI0 D19536g
gene id: 284591:YALI0_D19536g
uniprot id: Q6C8H6
names: Similarity
messages: Belongs to the CAND family.

284591:YALI0 E04983g
gene id: 284591:YALI0_E04983g
uniprot id: Q6C6Z8
names: Similarity
messages: Belongs to the cullin family.

284591:YALI0 E05599g
gene id: 284591:YALI0_E05599g
uniprot id: Q6C6X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADH dehydrogenase family.
messages: Mitochondrion inner membrane

284591:YALI0 D22110g
gene id: 284591:YALI0_D22110g
uniprot id: Q6C873
names: Similarity
messages: Belongs to the amidase family.

284591:YALI0 D06952g
gene id: 284591:YALI0_D06952g
uniprot id: Q6CA03
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 F08635g
gene id: 284591:YALI0_F08635g
uniprot id: Q6C2E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity).
messages: Nucleus

284591:YALI0 E07183g
gene id: 284591:YALI0_E07183g
uniprot id: Q6C6Q6
names: Similarity
messages: Belongs to the proteasome subunit S11 family.

284591:YALI0 F05346g
gene id: 284591:YALI0_F05346g
uniprot id: Q6C2T3
names: Similarity
messages: Belongs to the ERT1/acuK family.

284591:YALI0 F22935g
gene id: 284591:YALI0_F22935g
uniprot id: Q6C0P3
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

284591:YALI0 D19756g
gene id: 284591:YALI0_D19756g
uniprot id: Q6C8G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

284591:YALI0 B23364g
gene id: 284591:YALI0_B23364g
uniprot id: Q6CDJ9
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F28193g
gene id: 284591:YALI0_F28193g
uniprot id: Q6C031
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F09559g
gene id: 284591:YALI0_F09559g
uniprot id: Q6C299
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

284591:YALI0 D05335g
gene id: 284591:YALI0_D05335g
uniprot id: Q6CA72
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

284591:YALI0 F06116g
gene id: 284591:YALI0_F06116g
uniprot id: Q6C2P8
names: Function
names: Similarity
messages: Belongs to the Rab GDI family.
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

284591:YALI0 F25333g
gene id: 284591:YALI0_F25333g
uniprot id: Q6C0E8
names: Similarity
messages: Belongs to the peptidase M20A family.

284591:YALI0 E29073g
gene id: 284591:YALI0_E29073g
uniprot id: Q6C477
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

284591:YALI0 D17402g
gene id: 284591:YALI0_D17402g
uniprot id: Q6C8S4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

284591:YALI0 D04851g
gene id: 284591:YALI0_D04851g
uniprot id: Q6CA92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

284591:YALI0 A10032g
gene id: 284591:YALI0_A10032g
uniprot id: Q6CHD4
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

284591:YALI0 D23331g
gene id: 284591:YALI0_D23331g
uniprot id: Q6C826
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

284591:YALI0 F28061g
gene id: 284591:YALI0_F28061g
uniprot id: Q6C037
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates 60S ribosomal protein L42.

284591:YALI0 B07425g
gene id: 284591:YALI0_B07425g
uniprot id: Q6CFF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

284591:YALI0 F10857g
gene id: 284591:YALI0_F10857g
uniprot id: O74935
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acyl-CoA oxidase family.
messages: Heteropentamer composed of five different subunits.
messages: Oxidizes strain chain acyl-CoAs with a chain length of 10 to 14 carbons. Also active toward the 2S isomers of acyl-CoA-esters containing a 2-methyl group.
messages: Peroxisome

284591:YALI0 E28468g
gene id: 284591:YALI0_E28468g
uniprot id: Q6C4A4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.

284591:YALI0 A11517g
gene id: 284591:YALI0_A11517g
uniprot id: Q6CH80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

284591:YALI0 A21307g
gene id: 284591:YALI0_A21307g
uniprot id: Q6CG86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 E11869g
gene id: 284591:YALI0_E11869g
uniprot id: Q6C675
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

284591:YALI0 F21010g
gene id: 284591:YALI0_F21010g
uniprot id: Q99148
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Binds two magnesium or manganese ions per subunit.
messages: Catalyzes the second and fifth step in the 'de novo' purine biosynthesis pathway; contains phosphoribosylamine--glycine ligase (GARS) and phosphoribosylformylglycinamidine cyclo-ligase (AIRS) activities.
messages: In the C-terminal section; belongs to the AIR synthase family.
messages: In the N-terminal section; belongs to the GARS family.
messages: cytosol

284591:YALI0 F31383g
gene id: 284591:YALI0_F31383g
uniprot id: Q6BZR9
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

284591:YALI0 C10054g
gene id: 284591:YALI0_C10054g
uniprot id: Q6CCE5
names: Similarity
messages: Belongs to the cytochrome P450 family.

284591:YALI0 C22385g
gene id: 284591:YALI0_C22385g
uniprot id: Q6CB28
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

284591:YALI0 A07142g
gene id: 284591:YALI0_A07142g
uniprot id: Q6CHM5
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

284591:YALI0 E05115g
gene id: 284591:YALI0_E05115g
uniprot id: Q6C6Z2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer; composed of 3 copies of TIM9 and 3 copies of TIM10, named soluble 70 kDa complex. Associates with the TIM22 complex, whose core is composed of TIM22 and TIM54. Interacts with the transmembrane regions of multi-pass transmembrane proteins in transit (By similarity).
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. However, during the transit of TIM9 from cytoplasm into mitochondrion, the Cys residues probably coordinate zinc, thereby preventing folding and allowing its transfer across mitochondrial outer membrane (By similarity).

284591:YALI0 F23837g
gene id: 284591:YALI0_F23837g
uniprot id: Q6C0K8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

284591:YALI0 E27346g
gene id: 284591:YALI0_E27346g
uniprot id: Q6C4E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.

284591:YALI0 B03344g
gene id: 284591:YALI0_B03344g
uniprot id: Q6CFV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284591:YALI0 C13882g
gene id: 284591:YALI0_C13882g
uniprot id: Q6CC03
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

284591:YALI0 B20438g
gene id: 284591:YALI0_B20438g
uniprot id: Q6CDX6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

284591:YALI0 B02948g
gene id: 284591:YALI0_B02948g
uniprot id: Q9UVF4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: It is uncertain whether Met-1 or Met-14 is the initiator.

284591:YALI0 A04895g
gene id: 284591:YALI0_A04895g
uniprot id: Q6CHU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NPC2 family.
messages: Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
messages: Monomer.

284591:YALI0 F14795g
gene id: 284591:YALI0_F14795g
uniprot id: Q6C1N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

284591:YALI0 D00495g
gene id: 284591:YALI0_D00495g
uniprot id: Q6CAR8
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D20790g
gene id: 284591:YALI0_D20790g
uniprot id: Q6C8C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC22 family.
messages: Cytoplasm
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284591:YALI0 F05192g
gene id: 284591:YALI0_F05192g
uniprot id: Q6C2U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

284591:YALI0 D05401g
gene id: 284591:YALI0_D05401g
uniprot id: Q6CA69
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E09284g
gene id: 284591:YALI0_E09284g
uniprot id: Q6C6I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix.
messages: Mitochondrion inner membrane

284591:YALI0 B16610g
gene id: 284591:YALI0_B16610g
uniprot id: Q6CED1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Membrane
messages: nuclear pore complex

284591:YALI0 A00440g
gene id: 284591:YALI0_A00440g
uniprot id: Q6CI94
names: Similarity
messages: Belongs to the FUN14 family.

284591:YALI0 D26576g
gene id: 284591:YALI0_D26576g
uniprot id: Q6C7N9
names: Similarity
messages: Belongs to the SEN15 family.

284591:YALI0 E14597g
gene id: 284591:YALI0_E14597g
uniprot id: Q6C5W5
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

284591:YALI0 B08206g
gene id: 284591:YALI0_B08206g
uniprot id: P45815
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional regulator involved in resistance to high copper concentration.

284591:YALI0 F20504g
gene id: 284591:YALI0_F20504g
uniprot id: Q6C0Z6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Forms a one-to-one complex with cytochrome c.
messages: Mitochondrion matrix

284591:YALI0 F01012g
gene id: 284591:YALI0_F01012g
uniprot id: Q99155
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pex2/pex10/pex12 family.
messages: Component of the PEX2-PEX10-PEX12 retrotranslocation channel, composed of PEX2, PEX10 and PEX12.
messages: E3 ubiquitin-protein ligase component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling. The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane. PEX2 also regulates peroxisome organization by acting as a E3 ubiquitin-protein ligase. PEX2 ubiquitinates PEX5 during its passage through the retrotranslocation channel: catalyzes monoubiquitination of PEX5 at 'Cys-6', a modification that acts as a signal for PEX5 extraction into the cytosol.
messages: Peroxisome membrane
messages: The three subunits of the retrotranslocation channel (PEX2, PEX10 and PEX12) coassemble in the membrane into a channel with an open 10 Angstrom pore. The RING-type zinc-fingers that catalyze PEX5 receptor ubiquitination are positioned above the pore on the cytosolic side of the complex.

284591:YALI0 C21362g
gene id: 284591:YALI0_C21362g
uniprot id: Q6CB74
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

284591:YALI0 D20834g
gene id: 284591:YALI0_D20834g
uniprot id: Q6C8C4
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E01980g
gene id: 284591:YALI0_E01980g
uniprot id: Q6C7C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC24 family.
messages: Component of the NDC80 complex, which consists of NDC80, NUF2, SPC24 and SPC25.
messages: Nucleus
messages: kinetochore

284591:YALI0 F26367g
gene id: 284591:YALI0_F26367g
uniprot id: Q6C0A8
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.

284591:YALI0 B15246g
gene id: 284591:YALI0_B15246g
uniprot id: Q6CEJ1
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 F13541g
gene id: 284591:YALI0_F13541g
uniprot id: Q6C1T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase family.
messages: Cytoplasm

284591:YALI0 F01408g
gene id: 284591:YALI0_F01408g
uniprot id: Q6C3A3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C17501g
gene id: 284591:YALI0_C17501g
uniprot id: Q6CBL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-I/CTF3 family.
messages: Nucleus
messages: centromere

284591:YALI0 F19250g
gene id: 284591:YALI0_F19250g
uniprot id: Q6C149
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

284591:YALI0 E01188g
gene id: 284591:YALI0_E01188g
uniprot id: Q6C7F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHE9 family.
messages: Homooligomer.
messages: Mitochondrion inner membrane
messages: Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed (By similarity).

284591:YALI0 A20273g
gene id: 284591:YALI0_A20273g
uniprot id: Q6CGD4
names: Similarity
messages: Belongs to the multicopper oxidase family.

284591:YALI0 E25201g
gene id: 284591:YALI0_E25201g
uniprot id: Q6C4M7
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F26301g
gene id: 284591:YALI0_F26301g
uniprot id: Q6C0B1
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C11231g
gene id: 284591:YALI0_C11231g
uniprot id: Q6CC99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic component of the histone acetylase B (HAT-B) complex. Acetylates 'Lys-12' of histone H4 which is required for telomeric silencing. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.
messages: Component of the HAT-B complex composed of at least HAT1 and HAT2. The HAT-B complex binds to histone H4 tail (By similarity).
messages: Cytoplasm
messages: Nucleus

284591:YALI0 D20174g
gene id: 284591:YALI0_D20174g
uniprot id: Q6C8F1
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

284591:YALI0 D22616g
gene id: 284591:YALI0_D22616g
uniprot id: Q6C853
names: Similarity
messages: Belongs to the FMO family.

284591:YALI0 F06028g
gene id: 284591:YALI0_F06028g
uniprot id: Q6C2Q2
names: Similarity
messages: Belongs to the Toll-like receptor family.

284591:YALI0 D12562g
gene id: 284591:YALI0_D12562g
uniprot id: Q6C9B2
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 B21186g
gene id: 284591:YALI0_B21186g
uniprot id: Q6CDU2
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

284591:YALI0 E32857g
gene id: 284591:YALI0_E32857g
uniprot id: Q6C3Q8
names: Subunit
messages: Consists of at least two heavy chains and a number of intermediate and light chains.

284591:YALI0 D26367g
gene id: 284591:YALI0_D26367g
uniprot id: Q6C7P9
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

284591:YALI0 F21857g
gene id: 284591:YALI0_F21857g
uniprot id: Q6C0T7
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

284591:YALI0 F20284g
gene id: 284591:YALI0_F20284g
uniprot id: Q6C106
names: Similarity
messages: Belongs to the CBF/MAK21 family.

284591:YALI0 B22396g
gene id: 284591:YALI0_B22396g
uniprot id: Q6CDP3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

284591:YALI0 A00847g
gene id: 284591:YALI0_A00847g
uniprot id: Q6CI80
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

284591:YALI0 F30987g
gene id: 284591:YALI0_F30987g
uniprot id: Q6BZT7
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

284591:YALI0 C03784g
gene id: 284591:YALI0_C03784g
uniprot id: Q6CD49
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

284591:YALI0 C01419g
gene id: 284591:YALI0_C01419g
uniprot id: Q6CDD2
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.

284591:YALI0 E21109g
gene id: 284591:YALI0_E21109g
uniprot id: Q6C545
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

284591:YALI0 F02849g
gene id: 284591:YALI0_F02849g
uniprot id: Q6C340
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

284591:YALI0 E17787g
gene id: 284591:YALI0_E17787g
uniprot id: F2Z678
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Homotetramer.
messages: Versatile oxidoreductase that catalyzes the oxidation and reduction of a broad range of substrates. Preferentially oxidizes secondary alcohols. Has highest activity for racemic 2-octanol. Is also an efficient reductase for selected substrates. Substrate selectivity was found for medium chain lipophilic ketones. Has highest activities for 2-octanone, 2-nonanone and 2-decanone. The enzyme is (S)-selective in the reduction direction and produces exclusively the (S)-enantiomer.

284591:YALI0 E23067g
gene id: 284591:YALI0_E23067g
uniprot id: P41924
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic (By similarity).

284591:YALI0 F06820g
gene id: 284591:YALI0_F06820g
uniprot id: Q6C2L5
names: Similarity
messages: Belongs to the Fmt family.

284591:YALI0 A16868g
gene id: 284591:YALI0_A16868g
uniprot id: B5RSK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom7 family.
messages: Membrane
messages: Mitochondrion outer membrane

284591:YALI0 E30602g
gene id: 284591:YALI0_E30602g
uniprot id: B5FVF9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

284591:YALI0 E22902g
gene id: 284591:YALI0_E22902g
uniprot id: Q6C4X8
names: Similarity
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.

284591:YALI0 D14476g
gene id: 284591:YALI0_D14476g
uniprot id: Q6C939
names: Similarity
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

284591:YALI0 F13981g
gene id: 284591:YALI0_F13981g
uniprot id: Q6C1S0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E07535g
gene id: 284591:YALI0_E07535g
uniprot id: Q6C6P6
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

284591:YALI0 A02310g
gene id: 284591:YALI0_A02310g
uniprot id: Q6CI26
names: Function
names: Similarity
messages: Belongs to the UDPGP type 1 family.
messages: Plays a central role as a glucosyl donor in cellular metabolic pathways.

284591:YALI0 E03960g
gene id: 284591:YALI0_E03960g
uniprot id: Q6C741
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts in the GPI biosynthetic pathway between GlcNAc-PI synthesis and GPI transfer to protein.
messages: Belongs to the PIGF family.
messages: Endoplasmic reticulum membrane

284591:YALI0 F05962g
gene id: 284591:YALI0_F05962g
uniprot id: Q6C2Q5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

284591:YALI0 E19294g
gene id: 284591:YALI0_E19294g
uniprot id: Q6C5C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284591:YALI0 B09669g
gene id: 284591:YALI0_B09669g
uniprot id: Q6CF73
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

284591:YALI0 A19514g
gene id: 284591:YALI0_A19514g
uniprot id: Q6CGG7
names: Subcellular Location Annotation
messages: Cytoplasm

284591:YALI0 E23496g
gene id: 284591:YALI0_E23496g
uniprot id: Q6C4V0
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

284591:YALI0 F01034g
gene id: 284591:YALI0_F01034g
uniprot id: Q6C3B6
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

284591:YALI0 D20328g
gene id: 284591:YALI0_D20328g
uniprot id: Q6C8E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

284591:YALI0 E00176g
gene id: 284591:YALI0_E00176g
uniprot id: Q6C7K0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

284591:YALI0 F15917g
gene id: 284591:YALI0_F15917g
uniprot id: Q6C1I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

284591:YALI0 B08558g
gene id: 284591:YALI0_B08558g
uniprot id: Q6CFB5
names: Similarity
messages: Belongs to the protein kinase superfamily.

284591:YALI0 B10692g
gene id: 284591:YALI0_B10692g
uniprot id: Q6CF32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

284591:YALI0 E18304g
gene id: 284591:YALI0_E18304g
uniprot id: Q6C5G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERT1/acuK family.
messages: Nucleus
messages: Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes (By similarity).

284591:YALI0 C00803g
gene id: 284591:YALI0_C00803g
uniprot id: Q6CDG1
names: Similarity
messages: Belongs to the peptidase S10 family.

284591:YALI0 E16016g
gene id: 284591:YALI0_E16016g
uniprot id: Q6C5Q8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

284591:YALI0 F11055g
gene id: 284591:YALI0_F11055g
uniprot id: Q6C242
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

284591:YALI0 E19789g
gene id: 284591:YALI0_E19789g
uniprot id: Q6C5A0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284591:YALI0 E06919g
gene id: 284591:YALI0_E06919g
uniprot id: Q6C6R4
names: Similarity
messages: Belongs to the WD repeat RAPTOR family.

284591:YALI0 E01452g
gene id: 284591:YALI0_E01452g
uniprot id: Q6C7E6
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

284591:YALI0 F01496g
gene id: 284591:YALI0_F01496g
uniprot id: Q6C399
names: Similarity
messages: Belongs to the thioredoxin family.

284591:YALI0 E27247g
gene id: 284591:YALI0_E27247g
uniprot id: Q6C4F3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A03135g
gene id: 284591:YALI0_A03135g
uniprot id: Q6CHZ3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D04422g
gene id: 284591:YALI0_D04422g
uniprot id: F2Z6C9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion outer membrane
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis.

284591:YALI0 C19382g
gene id: 284591:YALI0_C19382g
uniprot id: Q6CBF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

284591:YALI0 D02002g
gene id: 284591:YALI0_D02002g
uniprot id: Q6CAK5
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F16819g
gene id: 284591:YALI0_F16819g
uniprot id: Q6C1F3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+) is required for catalysis and for stabilizing the dimer.

284591:YALI0 D11242g
gene id: 284591:YALI0_D11242g
uniprot id: Q6C9H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP9 family.
messages: RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).
messages: nucleolus

284591:YALI0 B10934g
gene id: 284591:YALI0_B10934g
uniprot id: Q6CF23
names: Similarity
messages: Belongs to the actin family.

284591:YALI0 D10681g
gene id: 284591:YALI0_D10681g
uniprot id: Q6C9J7
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E14949g
gene id: 284591:YALI0_E14949g
uniprot id: Q6C5V2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

284591:YALI0 E31867g
gene id: 284591:YALI0_E31867g
uniprot id: Q6C3V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NUF2 family.
messages: Component of the NDC80 complex, which consists of NDC80, NUF2, SPC24 and SPC25.
messages: Nucleus
messages: kinetochore

284591:YALI0 C16885g
gene id: 284591:YALI0_C16885g
uniprot id: P41555
names: Disruption Phenotype
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
messages: Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2-methylisocitrate.
messages: Glyoxysome
messages: Homotetramer.
messages: Inhibits the utilization of acetate, ethanol, and fatty acids, but also reduces the growth rate on glucose.

284591:YALI0 A02134g
gene id: 284591:YALI0_A02134g
uniprot id: Q6CI34
names: Subcellular Location Annotation
messages: nuclear pore complex

284591:YALI0 A02959g
gene id: 284591:YALI0_A02959g
uniprot id: Q6CI00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

284591:YALI0 E04048g
gene id: 284591:YALI0_E04048g
uniprot id: Q6C737
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284591:YALI0 E14795g
gene id: 284591:YALI0_E14795g
uniprot id: Q6C5V6
names: Similarity
messages: Belongs to the PP2C family.

284591:YALI0 F08745g
gene id: 284591:YALI0_F08745g
uniprot id: Q6C2D7
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

284591:YALI0 D17600g
gene id: 284591:YALI0_D17600g
uniprot id: Q6C8R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

284591:YALI0 A15257g
gene id: 284591:YALI0_A15257g
uniprot id: Q6CGX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WHI5/NRM1 family.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 A10252g
gene id: 284591:YALI0_A10252g
uniprot id: Q6CHC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPI1/TEX10 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex.
messages: Nucleus

284591:YALI0 A02112g
gene id: 284591:YALI0_A02112g
uniprot id: Q6CI35
names: Similarity
messages: Belongs to the SDHAF4 family.

284591:YALI0 C22275g
gene id: 284591:YALI0_C22275g
uniprot id: Q6CB33
names: Similarity
messages: Belongs to the syntaxin family.

284591:YALI0 F27225g
gene id: 284591:YALI0_F27225g
uniprot id: Q6C075
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

284591:YALI0 F11913g
gene id: 284591:YALI0_F11913g
uniprot id: Q6C204
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 4 family.
messages: Membrane

284591:YALI0 D04697g
gene id: 284591:YALI0_D04697g
uniprot id: Q6CA99
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

284591:YALI0 F05984g
gene id: 284591:YALI0_F05984g
uniprot id: Q6C2Q4
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B07249g
gene id: 284591:YALI0_B07249g
uniprot id: Q6CFG3
names: Function
names: Similarity
messages: Belongs to the LCL2 family.
messages: Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.

284591:YALI0 D00649g
gene id: 284591:YALI0_D00649g
uniprot id: Q6CAR2
names: Similarity
messages: Belongs to the AFG1 ATPase family.

284591:YALI0 F25047g
gene id: 284591:YALI0_F25047g
uniprot id: Q6C0G0
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

284591:YALI0 D05775g
gene id: 284591:YALI0_D05775g
uniprot id: Q6CA54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

284591:YALI0 E30085g
gene id: 284591:YALI0_E30085g
uniprot id: Q6C435
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FYV10 family.
messages: Cytoplasm
messages: Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.
messages: Nucleus

284591:YALI0 D26598g
gene id: 284591:YALI0_D26598g
uniprot id: Q6C7N8
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

284591:YALI0 B19338g
gene id: 284591:YALI0_B19338g
uniprot id: Q6CE18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

284591:YALI0 E33649g
gene id: 284591:YALI0_E33649g
uniprot id: Q6C3M2
names: Similarity
messages: Belongs to the Rab GDI family.

284591:YALI0 E31427g
gene id: 284591:YALI0_E31427g
uniprot id: Q6C3X7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. May also be involved in early transcription (By similarity).
messages: Associates with the nuclear pore complex.
messages: Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
messages: Cytoplasm
messages: Nucleus membrane
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nuclear pore complex

284591:YALI0 B14575g
gene id: 284591:YALI0_B14575g
uniprot id: Q6CEM2
names: Similarity
messages: Belongs to the thioesterase PaaI family.

284591:YALI0 E02662g
gene id: 284591:YALI0_E02662g
uniprot id: Q6C794
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG8 family.
messages: The C-terminal 8 residues are removed to expose Gly-116 at the C-terminus. The C-terminal Gly is then amidated with phosphatidylethanolamine by an activating system similar to that for ubiquitin.
messages: Ubiquitin-like modifier involved in autophagosomes formation. With ATG4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.
messages: Vacuole membrane
messages: autophagosome membrane

284591:YALI0 A02585g
gene id: 284591:YALI0_A02585g
uniprot id: Q6CI13
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM12 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane
messages: The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.

284591:YALI0 B06248g
gene id: 284591:YALI0_B06248g
uniprot id: Q6CFK2
names: Similarity
messages: Belongs to the cytochrome P450 family.

284591:YALI0 D17446g
gene id: 284591:YALI0_D17446g
uniprot id: Q6C8S2
names: Similarity
messages: Belongs to the peptidase M20A family.

284591:YALI0 D16137g
gene id: 284591:YALI0_D16137g
uniprot id: Q6C8X5
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B16324g
gene id: 284591:YALI0_B16324g
uniprot id: Q6CEE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chitin synthase family.
messages: Cell membrane
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

284591:YALI0 C24354g
gene id: 284591:YALI0_C24354g
uniprot id: Q6CAU0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B11913g
gene id: 284591:YALI0_B11913g
uniprot id: B5FVB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP19 family.
messages: F-type ATP synthases have 2 components, the catalytic core F(1) and the membrane-embedded component F(0), linked together by a central stalk and a peripheral stalk (PubMed:27373333). The central stalk, also called rotor shaft, is often seen as part of F(1) (PubMed:27373333). The peripheral stalk is seen as part of F(0) (PubMed:27373333). F(0) contains the membrane channel next to the rotor (PubMed:27373333). F-type ATP synthases form dimers but each monomer functions independently in ATP generation (PubMed:27373333). The dimer consists of 17 different polypeptides: ATP1 (subunit alpha, 3 molecules per monomer, part of F(1)), ATP2 (subunit beta, 3 copies per monomer, part of F(1)), ATP3 (subunit gamma, part of the central stalk), ATP4 (subunit b, part of the peripheral stalk), ATP5/OSCP (subunit 5/OSCP, part of the peripheral stalk), ATP6 (subunit a, part of the peripheral stalk), ATP7 (subunit d, part of the peripheral stalk), ATP8 (subunit 8, part of the peripheral stalk), OLI1 (subunit c, part of the rotor, 10 molecules per monomer), ATP14 (subunit h, part of the peripheral stalk), ATP15 (subunit epsilon, part of the central stalk), ATP16 (subunit delta, part of the central stalk), ATP17 (subunit f, part of the peripheral stalk), ATP18 (subunit i/j, part of the peripheral stalk), ATP19 (subunit k, dimer-specific, at interface between monomers), ATP20 (subunit g, at interface between monomers), TIM11 (subunit e, at interface between monomers) (PubMed:27373333, PubMed:25759169).
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169). F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27373333). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (PubMed:27373333). Part of the complex F(0) domain (PubMed:27373333). Minor subunit located with subunit a/ATP6 in the membrane (PubMed:27373333). The K/ATP19 chain binds the dimeric form by interacting with the G/ATP20 and E/TIM11 chains (PubMed:27373333).
messages: Mitochondrion inner membrane

284591:YALI0 C11803g
gene id: 284591:YALI0_C11803g
uniprot id: Q6CC75
names: Similarity
messages: Belongs to the PPase family.

284591:YALI0 B03982g
gene id: 284591:YALI0_B03982g
uniprot id: Q6CFT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATP synthases have 2 components, the catalytic core F(1) and the membrane-embedded component F(0), linked together by a central stalk and a peripheral stalk (PubMed:27373333). The central stalk, also called rotor shaft, is often seen as part of F(1) (PubMed:27373333). The peripheral stalk is seen as part of F(0) (PubMed:27373333). F(0) contains the membrane channel next to the rotor (PubMed:27373333). F-type ATP synthases form dimers but each monomer functions independently in ATP generation (PubMed:27373333). The dimer consists of 17 different polypeptides: ATP1 (subunit alpha, 3 molecules per monomer, part of F(1)), ATP2 (subunit beta, 3 copies per monomer, part of F(1)), ATP3 (subunit gamma, part of the central stalk), ATP4 (subunit b, part of the peripheral stalk), ATP5/OSCP (subunit 5/OSCP, part of the peripheral stalk), ATP6 (subunit a, part of the peripheral stalk), ATP7 (subunit d, part of the peripheral stalk), ATP8 (subunit 8, part of the peripheral stalk), OLI1 (subunit c, part of the rotor, 10 molecules per monomer), ATP14 (subunit h, part of the peripheral stalk), ATP15 (subunit epsilon, part of the central stalk), ATP16 (subunit delta, part of the central stalk), ATP17 (subunit f, part of the peripheral stalk), ATP18 (subunit i/j, part of the peripheral stalk), ATP19 (subunit k, dimer-specific, at interface between monomers), ATP20 (subunit g, at interface between monomers), TIM11 (subunit e, at interface between monomers) (PubMed:27373333, PubMed:25759169).
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169). F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27373333). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (PubMed:27373333). Subunits alpha/ATP1 and beta/ATP2 form the catalytic core in F(1) (PubMed:27373333). Rotation of the central stalk against the surrounding alpha/ATP1(3)beta/ATP2(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta/ATP2 subunits (PubMed:27373333).
messages: Mitochondrion inner membrane

284591:YALI0 D18964g
gene id: 284591:YALI0_D18964g
uniprot id: Q6C8K2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284591:YALI0 D17688g
gene id: 284591:YALI0_D17688g
uniprot id: Q6C8R1
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E07161g
gene id: 284591:YALI0_E07161g
uniprot id: Q6C6Q7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPK1 type 1 family.
messages: Has kinase activity and phosphorylates inositol-1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) to produce 1,2,3,4,5,6-hexakisphosphate (InsP6), also known as phytate.
messages: Nucleus
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

284591:YALI0 E09152g
gene id: 284591:YALI0_E09152g
uniprot id: Q6C6J0
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 F16225g
gene id: 284591:YALI0_F16225g
uniprot id: Q6C1H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

284591:YALI0 E31797g
gene id: 284591:YALI0_E31797g
uniprot id: Q6C3V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Endoplasmic reticulum membrane
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.

284591:YALI0 C20823g
gene id: 284591:YALI0_C20823g
uniprot id: Q6CB98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284591:YALI0 B17424g
gene id: 284591:YALI0_B17424g
uniprot id: Q6CE96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284591:YALI0 F31669g
gene id: 284591:YALI0_F31669g
uniprot id: Q6BZQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BOS1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: SNARE required for protein transport between the ER and the Golgi complex.

284591:YALI0 F05390g
gene id: 284591:YALI0_F05390g
uniprot id: Q12725
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
messages: Secreted

284591:YALI0 D17666g
gene id: 284591:YALI0_D17666g
uniprot id: Q6C8R2
names: Similarity
messages: Belongs to the PHAF1 family.

284591:YALI0 F12749g
gene id: 284591:YALI0_F12749g
uniprot id: Q6C1X0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 B04532g
gene id: 284591:YALI0_B04532g
uniprot id: Q6CFR3
names: Function
names: Similarity
messages: Belongs to the NARF family.
messages: Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).

284591:YALI0 F28017g
gene id: 284591:YALI0_F28017g
uniprot id: Q6C039
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A08360g
gene id: 284591:YALI0_A08360g
uniprot id: Q6CHI8
names: Similarity
messages: Belongs to the peptidase S8 family.

284591:YALI0 F08921g
gene id: 284591:YALI0_F08921g
uniprot id: Q6C2C9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit and an accessory subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284591:YALI0 C19866g
gene id: 284591:YALI0_C19866g
uniprot id: Q6CBD2
names: Similarity
messages: Belongs to the SurE nucleotidase family.

284591:YALI0 D08514g
gene id: 284591:YALI0_D08514g
uniprot id: Q6C9T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

284591:YALI0 D14850g
gene id: 284591:YALI0_D14850g
uniprot id: Q6C926
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

284591:YALI0 B00638g
gene id: 284591:YALI0_B00638g
uniprot id: Q6CG60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 E01584g
gene id: 284591:YALI0_E01584g
uniprot id: Q6C7E0
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

284591:YALI0 C15829g
gene id: 284591:YALI0_C15829g
uniprot id: Q6CBT0
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

284591:YALI0 F09834g
gene id: 284591:YALI0_F09834g
uniprot id: Q6C288
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S1 family.

284591:YALI0 D00847g
gene id: 284591:YALI0_D00847g
uniprot id: Q6CAQ3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F03861g
gene id: 284591:YALI0_F03861g
uniprot id: Q6C2Z5
names: Similarity
messages: Belongs to the CCZ1 family.

284591:YALI0 F27665g
gene id: 284591:YALI0_F27665g
uniprot id: Q6C055
names: Function
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.
messages: Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP.

284591:YALI0 E20449g
gene id: 284591:YALI0_E20449g
uniprot id: Q6C575
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E15686g
gene id: 284591:YALI0_E15686g
uniprot id: Q6C5S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBP4 family.
messages: Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b (By similarity).
messages: Mitochondrion inner membrane

284591:YALI0 C12254g
gene id: 284591:YALI0_C12254g
uniprot id: Q6CC58
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E09471g
gene id: 284591:YALI0_E09471g
uniprot id: O43108
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Golgi apparatus membrane
messages: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Has a role in the secretory pathway.

284591:YALI0 A00352g
gene id: 284591:YALI0_A00352g
uniprot id: Q6CI99
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

284591:YALI0 C11473g
gene id: 284591:YALI0_C11473g
uniprot id: Q6CC88
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

284591:YALI0 C12474g
gene id: 284591:YALI0_C12474g
uniprot id: Q6CC50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Membrane

284591:YALI0 F31911g
gene id: 284591:YALI0_F31911g
uniprot id: P09379
names: Function
messages: Most effectively accelerate the intrinsic GTPase activity of YPT7. It is also active, but to a lesser extent, on YPT31, YPT32 and YPT1. YPT6 and SEC4 (By similarity).

284591:YALI0 E33275g
gene id: 284591:YALI0_E33275g
uniprot id: Q6C3P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 28 family.
messages: Endoplasmic reticulum
messages: Heterodimer with ALG14 to form a functional enzyme.
messages: Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway (By similarity).

284591:YALI0 E21329g
gene id: 284591:YALI0_E21329g
uniprot id: Q6C537
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cell membrane

284591:YALI0 C18139g
gene id: 284591:YALI0_C18139g
uniprot id: Q6CBJ9
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

284591:YALI0 A19602g
gene id: 284591:YALI0_A19602g
uniprot id: Q6CGG3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. FKBP2 subfamily.
messages: Endoplasmic reticulum
messages: Inhibited by both FK506 and rapamycin.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

284591:YALI0 D17094g
gene id: 284591:YALI0_D17094g
uniprot id: Q6C8T6
names: Similarity
messages: Belongs to the PSMG1 family.

284591:YALI0 B21604g
gene id: 284591:YALI0_B21604g
uniprot id: Q6CDS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 C01243g
gene id: 284591:YALI0_C01243g
uniprot id: Q6CDE1
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E28248g
gene id: 284591:YALI0_E28248g
uniprot id: Q6C4B4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

284591:YALI0 F05803g
gene id: 284591:YALI0_F05803g
uniprot id: Q6C2R3
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

284591:YALI0 E20735g
gene id: 284591:YALI0_E20735g
uniprot id: Q6C562
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

284591:YALI0 F21637g
gene id: 284591:YALI0_F21637g
uniprot id: Q6C0U7
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 F10541g
gene id: 284591:YALI0_F10541g
uniprot id: Q6C262
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

284591:YALI0 F02893g
gene id: 284591:YALI0_F02893g
uniprot id: Q6C338
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATP synthases have 2 components, the catalytic core F(1) and the membrane-embedded component F(0), linked together by a central stalk and a peripheral stalk (PubMed:27373333). The central stalk, also called rotor shaft, is often seen as part of F(1) (PubMed:27373333). The peripheral stalk is seen as part of F(0) (PubMed:27373333). F(0) contains the membrane channel next to the rotor (PubMed:27373333). F-type ATP synthases form dimers but each monomer functions independently in ATP generation (PubMed:27373333). The dimer consists of 17 different polypeptides: ATP1 (subunit alpha, 3 molecules per monomer, part of F(1)), ATP2 (subunit beta, 3 copies per monomer, part of F(1)), ATP3 (subunit gamma, part of the central stalk), ATP4 (subunit b, part of the peripheral stalk), ATP5/OSCP (subunit 5/OSCP, part of the peripheral stalk), ATP6 (subunit a, part of the peripheral stalk), ATP7 (subunit d, part of the peripheral stalk), ATP8 (subunit 8, part of the peripheral stalk), OLI1 (subunit c, part of the rotor, 10 molecules per monomer), ATP14 (subunit h, part of the peripheral stalk), ATP15 (subunit epsilon, part of the central stalk), ATP16 (subunit delta, part of the central stalk), ATP17 (subunit f, part of the peripheral stalk), ATP18 (subunit i/j, part of the peripheral stalk), ATP19 (subunit k, dimer-specific, at interface between monomers), ATP20 (subunit g, at interface between monomers), TIM11 (subunit e, at interface between monomers) (PubMed:27373333, PubMed:25759169).
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169). F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27373333). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (PubMed:27373333). Part of the complex F(1) domain and the central stalk which is part of the complex rotary element (PubMed:27373333). The gamma/ATP3 subunit protrudes into the catalytic domain formed of alpha/ATP1(3)beta/ATP2(3) (PubMed:27373333). Rotation of the central stalk against the surrounding alpha/ATP1(3)beta/ATP2(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta/ATP2 subunits (PubMed:27373333).
messages: Mitochondrion inner membrane

284591:YALI0 B16192g
gene id: 284591:YALI0_B16192g
uniprot id: Q6CEE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Homotetramer.
messages: Versatile oxidoreductase that catalyzes the oxidation and reduction of polar as well as non-polar substrates at a very broad pH range. Preferentially oxidizes secondary alcohols. Has highest activity for racemic 2-heptanol and racemic octanol. Is also an efficient reductase for selected substrates. Substrate selectivity was found for medium chain length ketones with the carbonyl function at position C-2. Has highest activities for ribulose and fructose. The enzyme is (R)-selective in the reduction direction and produces exclusively the (R)-enantiomer.

284591:YALI0 E16709g
gene id: 284591:YALI0_E16709g
uniprot id: Q6C5M8
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

284591:YALI0 F14927g
gene id: 284591:YALI0_F14927g
uniprot id: Q6C1M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

284591:YALI0 D04334g
gene id: 284591:YALI0_D04334g
uniprot id: Q6CAB2
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

284591:YALI0 E04576g
gene id: 284591:YALI0_E04576g
uniprot id: Q6C715
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease (By similarity).

284591:YALI0 C09548g
gene id: 284591:YALI0_C09548g
uniprot id: Q6CCG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

284591:YALI0 B23342g
gene id: 284591:YALI0_B23342g
uniprot id: Q6CDK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. The complex is held together by ERB1, which interacts with NOP7 via its N-terminal domain and with YTM1 via a high-affinity interaction between the seven-bladed beta-propeller domains of the 2 proteins. The NOP7 complex associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

284591:YALI0 F19976g
gene id: 284591:YALI0_F19976g
uniprot id: Q6C119
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

284591:YALI0 C01903g
gene id: 284591:YALI0_C01903g
uniprot id: Q6CDB8
names: Similarity
messages: Belongs to the EAF family.

284591:YALI0 F04444g
gene id: 284591:YALI0_F04444g
uniprot id: Q6C2W9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

284591:YALI0 F14025g
gene id: 284591:YALI0_F14025g
uniprot id: Q6C1R8
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

284591:YALI0 D11858g
gene id: 284591:YALI0_D11858g
uniprot id: F2Z6I0
names: Subcellular Location Annotation
messages: Peroxisome membrane

284591:YALI0 D11627g
gene id: 284591:YALI0_D11627g
uniprot id: B5FVE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

284591:YALI0 E07139g
gene id: 284591:YALI0_E07139g
uniprot id: Q6C6Q8
names: Similarity
messages: Belongs to the XPO2/CSE1 family.

284591:YALI0 F23045g
gene id: 284591:YALI0_F23045g
uniprot id: Q6C0P0
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E21153g
gene id: 284591:YALI0_E21153g
uniprot id: Q6C543
names: Similarity
messages: Belongs to the peptidase C48 family.

284591:YALI0 E12837g
gene id: 284591:YALI0_E12837g
uniprot id: Q6C635
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

284591:YALI0 F07469g
gene id: 284591:YALI0_F07469g
uniprot id: Q6C2J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

284591:YALI0 E32703g
gene id: 284591:YALI0_E32703g
uniprot id: Q99158
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIL1 family.
messages: By the unfolded protein response (UPR).
messages: Endoplasmic reticulum lumen
messages: Interacts with KAR2.
messages: Required for protein translocation and folding in the endoplasmic reticulum (ER). Probably functions as a nucleotide exchange factor for the ER lumenal chaperone KAR2. It is not required for viability but is essential for optimal growth at elevated temperatures.

284591:YALI0 F01650g
gene id: 284591:YALI0_F01650g
uniprot id: Q6C392
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284591:YALI0 F05588g
gene id: 284591:YALI0_F05588g
uniprot id: Q6C2S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR55 family.
messages: nucleolus

284591:YALI0 E12081g
gene id: 284591:YALI0_E12081g
uniprot id: Q6C665
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284591:YALI0 E05621g
gene id: 284591:YALI0_E05621g
uniprot id: Q6C6W9
names: Similarity
messages: Belongs to the SH3YL1 family.

284591:YALI0 E26004g
gene id: 284591:YALI0_E26004g
uniprot id: Q6C4K5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

284591:YALI0 F16940g
gene id: 284591:YALI0_F16940g
uniprot id: Q6C1E8
names: Similarity
messages: Belongs to the OSBP family.

284591:YALI0 F02981g
gene id: 284591:YALI0_F02981g
uniprot id: Q6C334
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRD1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 E29447g
gene id: 284591:YALI0_E29447g
uniprot id: Q6C460
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane

284591:YALI0 E26048g
gene id: 284591:YALI0_E26048g
uniprot id: Q6C4K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Dus family. Dus3 subfamily.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs (By similarity). Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity).
messages: Cytoplasm
messages: Nucleus

284591:YALI0 F18480g
gene id: 284591:YALI0_F18480g
uniprot id: Q6C182
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Cytoplasm

284591:YALI0 F23397g
gene id: 284591:YALI0_F23397g
uniprot id: Q6C0M6
names: Similarity
messages: Belongs to the AAA ATPase family.

284591:YALI0 E05797g
gene id: 284591:YALI0_E05797g
uniprot id: Q6C6W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: nucleolus

284591:YALI0 F27709g
gene id: 284591:YALI0_F27709g
uniprot id: Q6C053
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D17028g
gene id: 284591:YALI0_D17028g
uniprot id: Q6C8U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 E06567g
gene id: 284591:YALI0_E06567g
uniprot id: Q6C6T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

284591:YALI0 E16555g
gene id: 284591:YALI0_E16555g
uniprot id: Q6C5N5
names: Similarity
messages: Belongs to the TRAPPC13 family.

284591:YALI0 A10076g
gene id: 284591:YALI0_A10076g
uniprot id: Q9Y753
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 two farnesyl pyrophosphate moieties to form squalene. It is the first committed enzyme of the sterol biosynthesis pathway. Required for the biosynthesis of ergosterol.
messages: Endoplasmic reticulum membrane

284591:YALI0 E05093g
gene id: 284591:YALI0_E05093g
uniprot id: Q6C6Z3
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E00308g
gene id: 284591:YALI0_E00308g
uniprot id: Q6C7J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

284591:YALI0 F24673g
gene id: 284591:YALI0_F24673g
uniprot id: Q6C0H4
names: Similarity
messages: Belongs to the UQCRH/QCR6 family.

284591:YALI0 A14498g
gene id: 284591:YALI0_A14498g
uniprot id: Q6CH03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 D21032g
gene id: 284591:YALI0_D21032g
uniprot id: Q6C8B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

284591:YALI0 E30283g
gene id: 284591:YALI0_E30283g
uniprot id: Q6C428
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B21230g
gene id: 284591:YALI0_B21230g
uniprot id: Q6CDU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 B17380g
gene id: 284591:YALI0_B17380g
uniprot id: Q6CE98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: actin patch

284591:YALI0 E09276g
gene id: 284591:YALI0_E09276g
uniprot id: Q6C6I4
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

284591:YALI0 B10560g
gene id: 284591:YALI0_B10560g
uniprot id: Q6CF36
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

284591:YALI0 C06930g
gene id: 284591:YALI0_C06930g
uniprot id: Q6CCS5
names: Similarity
messages: Belongs to the histidine acid phosphatase family.

284591:YALI0 F19448g
gene id: 284591:YALI0_F19448g
uniprot id: Q6C141
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dUTPase family.
messages: Homotrimer.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

284591:YALI0 F03432g
gene id: 284591:YALI0_F03432g
uniprot id: Q6C315
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activates the ATG1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy. Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation. Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy. Finally, ATG13 is also required for glycogen storage during stationary phase (By similarity).
messages: Belongs to the ATG13 family. Fungi subfamily.
messages: Cytoplasm
messages: Interacts with ATG1 to form the ATG1-ATG13 kinase complex.
messages: Preautophagosomal structure

284591:YALI0 C22319g
gene id: 284591:YALI0_C22319g
uniprot id: Q6CB31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that trimethylates elongation factor 1-alpha at 'Lys-79'.

284591:YALI0 F14333g
gene id: 284591:YALI0_F14333g
uniprot id: Q6C1Q4
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F31647g
gene id: 284591:YALI0_F31647g
uniprot id: Q6BZQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

284591:YALI0 D07788g
gene id: 284591:YALI0_D07788g
uniprot id: Q6C9W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

284591:YALI0 C20691g
gene id: 284591:YALI0_C20691g
uniprot id: Q6CBA4
names: Similarity
messages: Belongs to the peptidase S8 family.

284591:YALI0 F09768g
gene id: 284591:YALI0_F09768g
uniprot id: Q6C291
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrion-specific ribosomal protein mS37 family.
messages: Component of the mitochondrial small ribosomal subunit.
messages: Involved in mitochondrial genome encoded proteins translation.
messages: Mitochondrion

284591:YALI0 D02871g
gene id: 284591:YALI0_D02871g
uniprot id: Q6CAG8
names: Similarity
messages: Belongs to the peptidase C19 family.

284591:YALI0 C04323g
gene id: 284591:YALI0_C04323g
uniprot id: Q6CD26
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E06061g
gene id: 284591:YALI0_E06061g
uniprot id: Q6C6U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
messages: Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
messages: Endoplasmic reticulum membrane

284591:YALI0 E34749g
gene id: 284591:YALI0_E34749g
uniprot id: Q6C3H7
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

284591:YALI0 D08338g
gene id: 284591:YALI0_D08338g
uniprot id: Q6C9U3
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

284591:YALI0 A01738g
gene id: 284591:YALI0_A01738g
uniprot id: Q6CI49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

284591:YALI0 C00561g
gene id: 284591:YALI0_C00561g
uniprot id: Q6CDH2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284591:YALI0 E02310g
gene id: 284591:YALI0_E02310g
uniprot id: Q6C7A8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

284591:YALI0 D00231g
gene id: 284591:YALI0_D00231g
uniprot id: Q6CAT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XLF subfamily.
messages: Nucleus

284591:YALI0 B00462g
gene id: 284591:YALI0_B00462g
uniprot id: Q6CG66
names: Similarity
messages: Belongs to the CoA-transferase III family.

284591:YALI0 F01386g
gene id: 284591:YALI0_F01386g
uniprot id: Q6C3A4
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F00506g
gene id: 284591:YALI0_F00506g
uniprot id: Q6C3E0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Homooctamer.

284591:YALI0 E21219g
gene id: 284591:YALI0_E21219g
uniprot id: Q6C540
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

284591:YALI0 F12639g
gene id: 284591:YALI0_F12639g
uniprot id: Q6C1X5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: In the 2nd section; belongs to the EPSP synthase family.
messages: In the 3rd section; belongs to the shikimate kinase family.
messages: In the 4th section; belongs to the type-I 3-dehydroquinase family.
messages: In the C-terminal section; belongs to the shikimate dehydrogenase family.
messages: In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.

284591:YALI0 D06457g
gene id: 284591:YALI0_D06457g
uniprot id: Q6CA26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 14, 12 and 17 subunits, respectively.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process (By similarity).
messages: Nucleus

284591:YALI0 B17490g
gene id: 284591:YALI0_B17490g
uniprot id: Q6CE93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

284591:YALI0 C19646g
gene id: 284591:YALI0_C19646g
uniprot id: Q6CBE3
names: Similarity
messages: Belongs to the WrbA family.

284591:YALI0 F13607g
gene id: 284591:YALI0_F13607g
uniprot id: Q6C1T2
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D22847g
gene id: 284591:YALI0_D22847g
uniprot id: Q6C846
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion matrix

284591:YALI0 E00264g
gene id: 284591:YALI0_E00264g
uniprot id: Q6C7J6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

284591:YALI0 B03916g
gene id: 284591:YALI0_B03916g
uniprot id: Q6CFU0
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

284591:YALI0 E15356g
gene id: 284591:YALI0_E15356g
uniprot id: Q6C5T3
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 F25509g
gene id: 284591:YALI0_F25509g
uniprot id: Q6C0E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

284591:YALI0 B20966g
gene id: 284591:YALI0_B20966g
uniprot id: Q6CDV2
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

284591:YALI0 D26015g
gene id: 284591:YALI0_D26015g
uniprot id: Q6C7R4
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

284591:YALI0 B04422g
gene id: 284591:YALI0_B04422g
uniprot id: Q6CFR8
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B18128g
gene id: 284591:YALI0_B18128g
uniprot id: Q6CE69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REXO4 family.
messages: Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs (By similarity).
messages: Nucleus

284591:YALI0 B09647g
gene id: 284591:YALI0_B09647g
uniprot id: Q6CF74
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

284591:YALI0 B21670g
gene id: 284591:YALI0_B21670g
uniprot id: Q6CDS0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

284591:YALI0 B23144g
gene id: 284591:YALI0_B23144g
uniprot id: Q6CDK9
names: Similarity
messages: Belongs to the protein kinase superfamily.

284591:YALI0 E01166g
gene id: 284591:YALI0_E01166g
uniprot id: Q6C7F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Nucleus

284591:YALI0 F14443g
gene id: 284591:YALI0_F14443g
uniprot id: Q6C1P9
names: Function
names: Subcellular Location Annotation
messages: Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation.
messages: Nucleus

284591:YALI0 C23144g
gene id: 284591:YALI0_C23144g
uniprot id: Q6CAZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-3' exonuclease family.
messages: Cytoplasm
messages: Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.

284591:YALI0 B16918g
gene id: 284591:YALI0_B16918g
uniprot id: Q6CEB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

284591:YALI0 F18216g
gene id: 284591:YALI0_F18216g
uniprot id: Q6C194
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

284591:YALI0 A07447g
gene id: 284591:YALI0_A07447g
uniprot id: Q6CHM0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E34606g
gene id: 284591:YALI0_E34606g
uniprot id: Q6CHG3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

284591:YALI0 F05566g
gene id: 284591:YALI0_F05566g
uniprot id: Q6C2S4
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

284591:YALI0 D20504g
gene id: 284591:YALI0_D20504g
uniprot id: Q6C8D7
names: Similarity
messages: Belongs to the BolA/IbaG family.

284591:YALI0 C07172g
gene id: 284591:YALI0_C07172g
uniprot id: Q6CCR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

284591:YALI0 F18150g
gene id: 284591:YALI0_F18150g
uniprot id: Q6C197
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL54 family.
messages: Mitochondrion

284591:YALI0 F20218g
gene id: 284591:YALI0_F20218g
uniprot id: Q6C109
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284591:YALI0 B00616g
gene id: 284591:YALI0_B00616g
uniprot id: Q6CG61
names: Similarity
messages: Belongs to the polyadenylate-binding protein type-1 family.

284591:YALI0 B03476g
gene id: 284591:YALI0_B03476g
uniprot id: Q6CFV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

284591:YALI0 E28930g
gene id: 284591:YALI0_E28930g
uniprot id: B5FVF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

284591:YALI0 F09471g
gene id: 284591:YALI0_F09471g
uniprot id: Q6C2A3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Cytoplasm
messages: Nucleus
messages: This protein is considered an atypical serine/threonine kinase, because it lacks the conventional structural elements necessary for the substrate recognition as well as a lysine residue that in all other serine/threonine kinases participates in the catalytic event (By similarity). BUD32 has protein kinase activity in vitro, but in the context of the EKC/KEOPS complex, the catalytic subunit KAE1 switches the activity of BUD32 from kinase into ATPase (By similarity).
messages: telomere

284591:YALI0 D11374g
gene id: 284591:YALI0_D11374g
uniprot id: Q6C9G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

284591:YALI0 E00968g
gene id: 284591:YALI0_E00968g
uniprot id: Q6C7G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284591:YALI0 B09559g
gene id: 284591:YALI0_B09559g
uniprot id: Q6CF78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.
messages: Nucleus

284591:YALI0 A02849g
gene id: 284591:YALI0_A02849g
uniprot id: Q6CI05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

284591:YALI0 E20713g
gene id: 284591:YALI0_E20713g
uniprot id: Q6C563
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D20020g
gene id: 284591:YALI0_D20020g
uniprot id: Q6C8F8
names: Similarity
messages: Belongs to the RMD1/sif2 family.

284591:YALI0 B10450g
gene id: 284591:YALI0_B10450g
uniprot id: Q6CF41
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. FKBP1 subfamily.
messages: Cytoplasm
messages: Inhibited by both FK506 and rapamycin.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

284591:YALI0 D19514g
gene id: 284591:YALI0_D19514g
uniprot id: Q6C8H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Forms homooligomers. Interacts with MRS2.
messages: Mitochondrial inner membrane magnesium transporter required for mitochondrial magnesium homeostasis. Modulates the conductance of the MRS2 channel. Involved in the splicing of mRNA group II introns in mitochondria by affecting mitochondrial magnesium concentrations, which are critical for group II intron splicing.
messages: Mitochondrion inner membrane

284591:YALI0 D23441g
gene id: 284591:YALI0_D23441g
uniprot id: Q6C821
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 F14773g
gene id: 284591:YALI0_F14773g
uniprot id: Q6C1N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC3 family.
messages: Nucleus

284591:YALI0 C11011g
gene id: 284591:YALI0_C11011g
uniprot id: Q6CCA8
names: Similarity
messages: Belongs to the Tom22 family.

284591:YALI0 A03091g
gene id: 284591:YALI0_A03091g
uniprot id: Q6CHZ5
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D20394g
gene id: 284591:YALI0_D20394g
uniprot id: Q6C8E2
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 A15125g
gene id: 284591:YALI0_A15125g
uniprot id: Q6CGX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 E27808g
gene id: 284591:YALI0_E27808g
uniprot id: Q6C4C9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.
messages: Inhibited by both FK506 and rapamycin.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
messages: nucleolus

284591:YALI0 E20889g
gene id: 284591:YALI0_E20889g
uniprot id: Q6C555
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WRB/GET1 family.
messages: Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.

284591:YALI0 C09988g
gene id: 284591:YALI0_C09988g
uniprot id: Q6CCE8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

284591:YALI0 B02772g
gene id: 284591:YALI0_B02772g
uniprot id: Q6CFX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).

284591:YALI0 A20944g
gene id: 284591:YALI0_A20944g
uniprot id: Q6CGA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284591:YALI0 D17930g
gene id: 284591:YALI0_D17930g
uniprot id: Q6C8Q1
names: Cofactor
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Reduced FMN (FMNH(2)).

284591:YALI0 E27940g
gene id: 284591:YALI0_E27940g
uniprot id: Q6C4C3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: Phosphorylation at Ser-174 and Ser-175 promotes nuclear export.
messages: nucleolus

284591:YALI0 F11341g
gene id: 284591:YALI0_F11341g
uniprot id: Q6C229
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 12 family.
messages: Component of the SRB8-11 complex, which itself associates with the Mediator complex.
messages: Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
messages: Nucleus

284591:YALI0 F11583g
gene id: 284591:YALI0_F11583g
uniprot id: Q6C219
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

284591:YALI0 A12705g
gene id: 284591:YALI0_A12705g
uniprot id: Q6CH42
names: Similarity
messages: Belongs to the RNase H family.

284591:YALI0 E05291g
gene id: 284591:YALI0_E05291g
uniprot id: Q6C6Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

284591:YALI0 B22308g
gene id: 284591:YALI0_B22308g
uniprot id: F2Z672
names: Similarity
messages: Belongs to the hexokinase family.

284591:YALI0 A20152g
gene id: 284591:YALI0_A20152g
uniprot id: Q6CGD8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

284591:YALI0 D20350g
gene id: 284591:YALI0_D20350g
uniprot id: Q6C8E3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D01155g
gene id: 284591:YALI0_D01155g
uniprot id: Q6CAN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Involved in pre-mRNA splicing. Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site. Involved in cap modification.
messages: Nucleus

284591:YALI0 E18051g
gene id: 284591:YALI0_E18051g
uniprot id: Q6C5H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Nucleus

284591:YALI0 C23727g
gene id: 284591:YALI0_C23727g
uniprot id: Q6CAW9
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 D06930g
gene id: 284591:YALI0_D06930g
uniprot id: Q6CA04
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

284591:YALI0 A02416g
gene id: 284591:YALI0_A02416g
uniprot id: P41927
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 11 family.

284591:YALI0 E10813g
gene id: 284591:YALI0_E10813g
uniprot id: Q6C6B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 F19206g
gene id: 284591:YALI0_F19206g
uniprot id: Q6C151
names: Similarity
messages: Belongs to the pirin family.

284591:YALI0 B00286g
gene id: 284591:YALI0_B00286g
uniprot id: Q6CG72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

284591:YALI0 D00363g
gene id: 284591:YALI0_D00363g
uniprot id: Q6CAS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 A02423g
gene id: 284591:YALI0_A02423g
uniprot id: P41928
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 11 family.

284591:YALI0 E34037g
gene id: 284591:YALI0_E34037g
uniprot id: Q6C3K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with cytochrome c oxidase (complex IV, CIV).
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Mitochondrion inner membrane

284591:YALI0 C18481g
gene id: 284591:YALI0_C18481g
uniprot id: Q9HFC9
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 11 family.

284591:YALI0 E02772g
gene id: 284591:YALI0_E02772g
uniprot id: Q8WZM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates histone H2B to form H2BK11ac and H2BK16ac, histone H3 to form H3K14ac, with a lower preference histone H4 to form H4K8ac and H4K16ac, and contributes to H2A.Z acetylation. Acetylation of histones gives a specific tag for epigenetic transcription activation (By similarity).
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus

284591:YALI0 E11671g
gene id: 284591:YALI0_E11671g
uniprot id: Q6C682
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

284591:YALI0 E27533g
gene id: 284591:YALI0_E27533g
uniprot id: Q6C4E0
names: Similarity
messages: Belongs to the PP2C family.

284591:YALI0 A08217g
gene id: 284591:YALI0_A08217g
uniprot id: Q6CHJ3
names: Similarity
messages: Belongs to the SurE nucleotidase family.

284591:YALI0 C00605g
gene id: 284591:YALI0_C00605g
uniprot id: Q6CDH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
messages: Cytoplasm
messages: Nucleus
messages: Part of the nascent polypeptide-associated complex (NAC), consisting of EGD2 and EGD1. NAC associates with ribosomes via EGD1 (By similarity).

284591:YALI0 A09988g
gene id: 284591:YALI0_A09988g
uniprot id: Q6CHD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.
messages: Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity).
messages: Mitochondrion matrix

284591:YALI0 F27863g
gene id: 284591:YALI0_F27863g
uniprot id: Q6C046
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
messages: Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

284591:YALI0 E32043g
gene id: 284591:YALI0_E32043g
uniprot id: Q6C3U5
names: Subcellular Location Annotation
messages: nucleolus

284591:YALI0 B07689g
gene id: 284591:YALI0_B07689g
uniprot id: Q6CFE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3' to 5' exoribonuclease required for proper 3' end maturation of MRP RNA and of the U5L snRNA.
messages: Belongs to the REXO1/REXO3 family.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 C18359g
gene id: 284591:YALI0_C18359g
uniprot id: Q6CBI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Endoplasmic reticulum membrane
messages: Functions as a zinc transporter.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

284591:YALI0 F31163g
gene id: 284591:YALI0_F31163g
uniprot id: Q6BZS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

284591:YALI0 C00253g
gene id: 284591:YALI0_C00253g
uniprot id: Q6CDI5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

284591:YALI0 B09845g
gene id: 284591:YALI0_B09845g
uniprot id: Q6CF67
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

284591:YALI0 E06237g
gene id: 284591:YALI0_E06237g
uniprot id: Q6C6U1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer; composed of 3 copies of TIM9 and 3 copies of TIM10, named soluble 70 kDa complex. Associates directly with the TIM22 complex, whose core is composed of TIM22 and TIM54. Interacts with the transmembrane regions of multi-pass transmembrane proteins in transit (By similarity).
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. However, during the transit of TIM10 from cytoplasm into mitochondrion, the Cys residues probably coordinate zinc, thereby preventing folding and allowing its transfer across mitochondrial outer membrane (By similarity).

284591:YALI0 B06534g
gene id: 284591:YALI0_B06534g
uniprot id: Q6CFJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

284591:YALI0 D26862g
gene id: 284591:YALI0_D26862g
uniprot id: Q6C7M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.
messages: Nucleus

284591:YALI0 D18788g
gene id: 284591:YALI0_D18788g
uniprot id: Q6C8L0
names: Similarity
messages: Belongs to the WD repeat mio family.

284591:YALI0 D07942g
gene id: 284591:YALI0_D07942g
uniprot id: Q6C9V7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

284591:YALI0 D26642g
gene id: 284591:YALI0_D26642g
uniprot id: Q6C7N6
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

284591:YALI0 C05082g
gene id: 284591:YALI0_C05082g
uniprot id: Q6CD02
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

284591:YALI0 B02090g
gene id: 284591:YALI0_B02090g
uniprot id: Q6CG01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284591:YALI0 F28765g
gene id: 284591:YALI0_F28765g
uniprot id: Q6C009
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284591:YALI0 D02497g
gene id: 284591:YALI0_D02497g
uniprot id: Q6CAI4
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

284591:YALI0 B04334g
gene id: 284591:YALI0_B04334g
uniprot id: Q6CFS2
names: Similarity
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.

284591:YALI0 E21670g
gene id: 284591:YALI0_E21670g
uniprot id: Q6C523
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC3 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).

284591:YALI0 A09680g
gene id: 284591:YALI0_A09680g
uniprot id: Q6CHE7
names: Similarity
names: Subunit
messages: Belongs to the EXO5 family.
messages: Monomer.

284591:YALI0 D20416g
gene id: 284591:YALI0_D20416g
uniprot id: Q6C8E1
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

284591:YALI0 B17666g
gene id: 284591:YALI0_B17666g
uniprot id: Q6CE87
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the NAGSA dehydrogenase family.
messages: In the N-terminal section; belongs to the acetylglutamate kinase family.
messages: Mitochondrion

284591:YALI0 F10923g
gene id: 284591:YALI0_F10923g
uniprot id: Q6C246
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.

284591:YALI0 D25102g
gene id: 284591:YALI0_D25102g
uniprot id: Q6C7V2
names: Similarity
messages: Belongs to the CSN1 family.

284591:YALI0 E30811g
gene id: 284591:YALI0_E30811g
uniprot id: Q6C406
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

284591:YALI0 E18095g
gene id: 284591:YALI0_E18095g
uniprot id: Q6C5H1
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F25795g
gene id: 284591:YALI0_F25795g
uniprot id: Q6C0C9
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D24497g
gene id: 284591:YALI0_D24497g
uniprot id: Q6C7X8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284591:YALI0 F08569g
gene id: 284591:YALI0_F08569g
uniprot id: Q6C2E5
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

284591:YALI0 A02200g
gene id: 284591:YALI0_A02200g
uniprot id: Q6CI31
names: Similarity
messages: Belongs to the cullin family.

284591:YALI0 F24321g
gene id: 284591:YALI0_F24321g
uniprot id: Q6C0I8
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

284591:YALI0 D04741g
gene id: 284591:YALI0_D04741g
uniprot id: Q6CA97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

284591:YALI0 D18337g
gene id: 284591:YALI0_D18337g
uniprot id: Q6C8N1
names: Similarity
messages: Belongs to the allantoicase family.

284591:YALI0 B17204g
gene id: 284591:YALI0_B17204g
uniprot id: Q6CEA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG2 family.
messages: Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.
messages: Endoplasmic reticulum membrane

284591:YALI0 A07799g
gene id: 284591:YALI0_A07799g
uniprot id: Q6CHK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane. Modulates the mitochondrial matrix zinc pool (By similarity).
messages: Belongs to the complex I LYR family. MZM1 subfamily.
messages: Interacts with RIP1.
messages: Mitochondrion matrix

284591:YALI0 E26433g
gene id: 284591:YALI0_E26433g
uniprot id: Q6C4I8
names: Similarity
messages: Belongs to the UPF0045 family.

284591:YALI0 B15510g
gene id: 284591:YALI0_B15510g
uniprot id: Q6CEH8
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

284591:YALI0 F05764g
gene id: 284591:YALI0_F05764g
uniprot id: Q6C2R5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284591:YALI0 C03333g
gene id: 284591:YALI0_C03333g
uniprot id: Q6CD69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

284591:YALI0 E00550g
gene id: 284591:YALI0_E00550g
uniprot id: Q6C7I6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

284591:YALI0 A12045g
gene id: 284591:YALI0_A12045g
uniprot id: Q6CH62
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

284591:YALI0 B16588g
gene id: 284591:YALI0_B16588g
uniprot id: Q6CED2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 F01584g
gene id: 284591:YALI0_F01584g
uniprot id: Q6C395
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.

284591:YALI0 B09471g
gene id: 284591:YALI0_B09471g
uniprot id: Q6CF81
names: Similarity
messages: Belongs to the band 7/mec-2 family.

284591:YALI0 F08899g
gene id: 284591:YALI0_F08899g
uniprot id: Q6C2D0
names: Subcellular Location Annotation
messages: Mitochondrion outer membrane

284591:YALI0 B22638g
gene id: 284591:YALI0_B22638g
uniprot id: Q6CDN2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284591:YALI0 B01034g
gene id: 284591:YALI0_B01034g
uniprot id: Q6CG42
names: Similarity
messages: Belongs to the eIF-2-alpha family.

284591:YALI0 C18029g
gene id: 284591:YALI0_C18029g
uniprot id: Q6CBK4
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

284591:YALI0 D05731g
gene id: 284591:YALI0_D05731g
uniprot id: Q6CA56
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

284591:YALI0 F16071g
gene id: 284591:YALI0_F16071g
uniprot id: Q6C1I0
names: Similarity
messages: Belongs to the BolA/IbaG family.

284591:YALI0 E27786g
gene id: 284591:YALI0_E27786g
uniprot id: Q6C4D0
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

284591:YALI0 E26851g
gene id: 284591:YALI0_E26851g
uniprot id: Q6C4H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit F family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

284591:YALI0 F20592g
gene id: 284591:YALI0_F20592g
uniprot id: Q6C0Z2
names: Similarity
messages: Belongs to the peptidase M18 family.

284591:YALI0 B05742g
gene id: 284591:YALI0_B05742g
uniprot id: Q6CFM0
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

284591:YALI0 D06435g
gene id: 284591:YALI0_D06435g
uniprot id: Q6CA27
names: Similarity
messages: Belongs to the WD repeat WDR48 family.

284591:YALI0 E22935g
gene id: 284591:YALI0_E22935g
uniprot id: Q6C4X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

284591:YALI0 B04378g
gene id: 284591:YALI0_B04378g
uniprot id: Q6CFS0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E15488g
gene id: 284591:YALI0_E15488g
uniprot id: Q6C5S9
names: Similarity
messages: Belongs to the hexokinase family.

284591:YALI0 C11363g
gene id: 284591:YALI0_C11363g
uniprot id: Q6CC93
names: Function
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.

284591:YALI0 D09779g
gene id: 284591:YALI0_D09779g
uniprot id: Q6C9N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus
messages: Part of the chromatin structure-remodeling complex (RSC) which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton. This subunit is essential for mitotic growth and required for cell cycle progression (By similarity).

284591:YALI0 C20933g
gene id: 284591:YALI0_C20933g
uniprot id: Q6CB95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
messages: Interacts with the MHF histone-fold complex to form the FANCM-MHF complex.
messages: Nucleus

284591:YALI0 F11869g
gene id: 284591:YALI0_F11869g
uniprot id: Q6C206
names: Similarity
messages: Belongs to the SAPS family.

284591:YALI0 B18304g
gene id: 284591:YALI0_B18304g
uniprot id: Q6CE61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit and an accessory subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

284591:YALI0 B16822g
gene id: 284591:YALI0_B16822g
uniprot id: Q6CEC1
names: Similarity
messages: Belongs to the VPS54 family.

284591:YALI0 F24343g
gene id: 284591:YALI0_F24343g
uniprot id: Q6C0I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDE2 family.
messages: Nucleus

284591:YALI0 C18161g
gene id: 284591:YALI0_C18161g
uniprot id: Q6CBJ8
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

284591:YALI0 E02332g
gene id: 284591:YALI0_E02332g
uniprot id: Q6C7A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

284591:YALI0 F12947g
gene id: 284591:YALI0_F12947g
uniprot id: Q6C1W1
names: Function
names: Similarity
messages: Belongs to the IRC6 family.
messages: Involved in gross chromosomal rearrangements (GCRs) and telomere healing.

284591:YALI0 D16643g
gene id: 284591:YALI0_D16643g
uniprot id: Q6C8V7
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

284591:YALI0 A18425g
gene id: 284591:YALI0_A18425g
uniprot id: Q6CGL0
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

284591:YALI0 D11814g
gene id: 284591:YALI0_D11814g
uniprot id: Q6C9E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase F chain family.
messages: F-type ATP synthases have 2 components, the catalytic core F(1) and the membrane-embedded component F(0), linked together by a central stalk and a peripheral stalk (PubMed:27373333). The central stalk, also called rotor shaft, is often seen as part of F(1) (PubMed:27373333). The peripheral stalk is seen as part of F(0) (PubMed:27373333). F(0) contains the membrane channel next to the rotor (PubMed:27373333). F-type ATP synthases form dimers but each monomer functions independently in ATP generation (PubMed:27373333). The dimer consists of 17 different polypeptides: ATP1 (subunit alpha, 3 molecules per monomer, part of F(1)), ATP2 (subunit beta, 3 copies per monomer, part of F(1)), ATP3 (subunit gamma, part of the central stalk), ATP4 (subunit b, part of the peripheral stalk), ATP5/OSCP (subunit 5/OSCP, part of the peripheral stalk), ATP6 (subunit a, part of the peripheral stalk), ATP7 (subunit d, part of the peripheral stalk), ATP8 (subunit 8, part of the peripheral stalk), OLI1 (subunit c, part of the rotor, 10 molecules per monomer), ATP14 (subunit h, part of the peripheral stalk), ATP15 (subunit epsilon, part of the central stalk), ATP16 (subunit delta, part of the central stalk), ATP17 (subunit f, part of the peripheral stalk), ATP18 (subunit i/j, part of the peripheral stalk), ATP19 (subunit k, dimer-specific, at interface between monomers), ATP20 (subunit g, at interface between monomers), TIM11 (subunit e, at interface between monomers) (PubMed:27373333, PubMed:25759169).
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169). F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27373333). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (PubMed:27373333). Part of the complex F(0) domain (PubMed:27373333). Minor subunit located with subunit a/ATP6 in the membrane (PubMed:27373333).
messages: Mitochondrion inner membrane

284591:YALI0 C09185g
gene id: 284591:YALI0_C09185g
uniprot id: Q6CCI2
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 D00759g
gene id: 284591:YALI0_D00759g
uniprot id: Q6CAQ7
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C15851g
gene id: 284591:YALI0_C15851g
uniprot id: Q6CBS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG27 family.
messages: Cytoplasmic vesicle membrane
messages: Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre-autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity).
messages: Golgi apparatus membrane
messages: Mitochondrion membrane
messages: Preautophagosomal structure membrane

284591:YALI0 F30151g
gene id: 284591:YALI0_F30151g
uniprot id: Q6BZX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat SEC13 family.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
messages: Endoplasmic reticulum membrane
messages: The COPII coat is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex, and the protein SAR1. Component of the nuclear pore complex (NPC). NPC constitutes the exclusive means of nucleocytoplasmic transport. NPCs allow the passive diffusion of ions and small molecules and the active, nuclear transport receptor-mediated bidirectional transport of macromolecules such as proteins, RNAs, ribonucleoparticles (RNPs), and ribosomal subunits across the nuclear envelope. Due to its 8-fold rotational symmetry, all subunits are present with 8 copies or multiples thereof.
messages: nuclear pore complex

284591:YALI0 E22649g
gene id: 284591:YALI0_E22649g
uniprot id: Q6C4Y7
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.

284591:YALI0 A18920g
gene id: 284591:YALI0_A18920g
uniprot id: Q6CGJ0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C07348g
gene id: 284591:YALI0_C07348g
uniprot id: Q6CCQ9
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F29843g
gene id: 284591:YALI0_F29843g
uniprot id: Q6BZY8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284591:YALI0 F23793g
gene id: 284591:YALI0_F23793g
uniprot id: Q6C0L0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

284591:YALI0 C22572g
gene id: 284591:YALI0_C22572g
uniprot id: Q6CB19
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F08393g
gene id: 284591:YALI0_F08393g
uniprot id: Q6C2F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAC-beta family.
messages: Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD1 may act as a transcription factor that exert a negative effect on the expression of several genes that are transcribed by RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Part of the nascent polypeptide-associated complex (NAC), consisting of EGD2 and EGD1. NAC associates with ribosomes via EGD1 (By similarity).

284591:YALI0 F23265g
gene id: 284591:YALI0_F23265g
uniprot id: Q6C0N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

284591:YALI0 E21780g
gene id: 284591:YALI0_E21780g
uniprot id: Q6C520
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Early endosome membrane
messages: Golgi apparatus membrane
messages: Palmitoyltransferase specific for casein kinase 1.
messages: The DHHC domain is required for palmitoyltransferase activity.

284591:YALI0 D06039g
gene id: 284591:YALI0_D06039g
uniprot id: Q6CA43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

284591:YALI0 E20581g
gene id: 284591:YALI0_E20581g
uniprot id: Q6C569
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

284591:YALI0 A20504g
gene id: 284591:YALI0_A20504g
uniprot id: Q6CGC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin 150 kDa subunit family.
messages: cytoskeleton

284591:YALI0 D02629g
gene id: 284591:YALI0_D02629g
uniprot id: Q6CAH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 F14905g
gene id: 284591:YALI0_F14905g
uniprot id: Q6C1M8
names: Similarity
messages: Belongs to the UPF0357 family.

284591:YALI0 C12056g
gene id: 284591:YALI0_C12056g
uniprot id: Q6CC66
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

284591:YALI0 E14465g
gene id: 284591:YALI0_E14465g
uniprot id: Q6C5W9
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

284591:YALI0 E23265g
gene id: 284591:YALI0_E23265g
uniprot id: Q6C4W1
names: Similarity
messages: Belongs to the WD repeat rae1 family.

284591:YALI0 E04785g
gene id: 284591:YALI0_E04785g
uniprot id: Q6C705
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat TRM82 family.
messages: Forms a heterodimer with the catalytic subunit TRM8.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

284591:YALI0 F12397g
gene id: 284591:YALI0_F12397g
uniprot id: Q9UVF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the palH/RIM21 family.
messages: Cell membrane
messages: Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.

284591:YALI0 F25729g
gene id: 284591:YALI0_F25729g
uniprot id: Q6C0D2
names: Similarity
messages: Belongs to the RNase H family.

284591:YALI0 C06600g
gene id: 284591:YALI0_C06600g
uniprot id: Q6CCT8
names: Similarity
messages: Belongs to the MIX23 family.

284591:YALI0 D07436g
gene id: 284591:YALI0_D07436g
uniprot id: Q6C9Y1
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

284591:YALI0 B13376g
gene id: 284591:YALI0_B13376g
uniprot id: Q6CES5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

284591:YALI0 B16786g
gene id: 284591:YALI0_B16786g
uniprot id: Q6CEC3
names: Similarity
messages: Belongs to the VPS25 family.

284591:YALI0 E07315g
gene id: 284591:YALI0_E07315g
uniprot id: Q6C6Q2
names: Similarity
messages: Belongs to the TPP enzyme family.

284591:YALI0 B06512g
gene id: 284591:YALI0_B06512g
uniprot id: Q6CFJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the timeless family.
messages: Component of the fork protection complex (FPC) consisting of TOF1 and CSM3.
messages: Forms a fork protection complex (FPC) with CSM3 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity).
messages: Nucleus

284591:YALI0 A10098g
gene id: 284591:YALI0_A10098g
uniprot id: Q6CHD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Component of the GSE complex.
messages: GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.

284591:YALI0 E11891g
gene id: 284591:YALI0_E11891g
uniprot id: Q6C674
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I NDUFA11 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

284591:YALI0 E10769g
gene id: 284591:YALI0_E10769g
uniprot id: Q6C6B8
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

284591:YALI0 C22528g
gene id: 284591:YALI0_C22528g
uniprot id: Q6CB21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DSS1/SEM1 family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Nucleus

284591:YALI0 F00154g
gene id: 284591:YALI0_F00154g
uniprot id: Q6C3F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

284591:YALI0 F23441g
gene id: 284591:YALI0_F23441g
uniprot id: Q6C0M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.

284591:YALI0 D11000g
gene id: 284591:YALI0_D11000g
uniprot id: Q6C9I2
names: Similarity
messages: Belongs to the RNase PH family.

284591:YALI0 C01595g
gene id: 284591:YALI0_C01595g
uniprot id: Q6CDC8
names: Function
names: Similarity
messages: Belongs to the SEC10 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

284591:YALI0 D11220g
gene id: 284591:YALI0_D11220g
uniprot id: Q6C9H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

284591:YALI0 D06523g
gene id: 284591:YALI0_D06523g
uniprot id: Q6CA23
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 D08272g
gene id: 284591:YALI0_D08272g
uniprot id: Q9UVF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
messages: Belongs to the actin family.
messages: cytoskeleton

284591:YALI0 F31229g
gene id: 284591:YALI0_F31229g
uniprot id: Q6BZS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INP1 family.
messages: Membrane
messages: Peroxisome membrane
messages: Required for peroxisome inheritance.

284591:YALI0 B05720g
gene id: 284591:YALI0_B05720g
uniprot id: Q6CFM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.
messages: cis-Golgi network

284591:YALI0 E12683g
gene id: 284591:YALI0_E12683g
uniprot id: Q6C638
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

284591:YALI0 E14212g
gene id: 284591:YALI0_E14212g
uniprot id: Q6C5X8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL28 family.

284591:YALI0 F04095g
gene id: 284591:YALI0_F04095g
uniprot id: Q6C2Y4
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

284591:YALI0 A19030g
gene id: 284591:YALI0_A19030g
uniprot id: Q6CGI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

284591:YALI0 A02409g
gene id: 284591:YALI0_A02409g
uniprot id: Q6CI21
names: Similarity
messages: Belongs to the RNase H family.

284591:YALI0 D17424g
gene id: 284591:YALI0_D17424g
uniprot id: Q6C8S3
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

284591:YALI0 B04928g
gene id: 284591:YALI0_B04928g
uniprot id: Q6CFQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NifU family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the core Fe-S cluster (ISC) assembly machinery.
messages: Mitochondrion matrix
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster assembly on ISU1 depends on the function of the cysteine desulfurase complex NFS1-ISD11, which serves as the sulfur donor for cluster synthesis, the iron-binding protein frataxin as the putative iron donor, and the electron transfer chain comprised of ferredoxin reductase and ferredoxin, which receive their electrons from NADH.

284591:YALI0 F19514g
gene id: 284591:YALI0_F19514g
uniprot id: Q6C138
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B00946g
gene id: 284591:YALI0_B00946g
uniprot id: Q6CG46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: Required for pre-18S rRNA processing. May bind microtubules (By similarity).
messages: nucleolus

284591:YALI0 D11836g
gene id: 284591:YALI0_D11836g
uniprot id: Q6C9E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

284591:YALI0 E31064g
gene id: 284591:YALI0_E31064g
uniprot id: Q6C3Z4
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C09460g
gene id: 284591:YALI0_C09460g
uniprot id: Q6CCH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with DRE2; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Mitochondrion
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. Positively controls H(2)O(2)-induced cell death.

284591:YALI0 F22077g
gene id: 284591:YALI0_F22077g
uniprot id: Q6C0S7
names: Similarity
messages: Belongs to the SHQ1 family.

284591:YALI0 D03949g
gene id: 284591:YALI0_D03949g
uniprot id: B5FVD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

284591:YALI0 E12133g
gene id: 284591:YALI0_E12133g
uniprot id: Q6C662
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homodimer.

284591:YALI0 B15224g
gene id: 284591:YALI0_B15224g
uniprot id: Q6CEJ2
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

284591:YALI0 A14883g
gene id: 284591:YALI0_A14883g
uniprot id: Q6CGY6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B21527g
gene id: 284591:YALI0_B21527g
uniprot id: B5FVB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase g subunit family.
messages: F-type ATP synthases have 2 components, the catalytic core F(1) and the membrane-embedded component F(0), linked together by a central stalk and a peripheral stalk (PubMed:27373333). The central stalk, also called rotor shaft, is often seen as part of F(1) (PubMed:27373333). The peripheral stalk is seen as part of F(0) (PubMed:27373333). F(0) contains the membrane channel next to the rotor (PubMed:27373333). F-type ATP synthases form dimers but each monomer functions independently in ATP generation (PubMed:27373333). The dimer consists of 17 different polypeptides: ATP1 (subunit alpha, 3 molecules per monomer, part of F(1)), ATP2 (subunit beta, 3 copies per monomer, part of F(1)), ATP3 (subunit gamma, part of the central stalk), ATP4 (subunit b, part of the peripheral stalk), ATP5/OSCP (subunit 5/OSCP, part of the peripheral stalk), ATP6 (subunit a, part of the peripheral stalk), ATP7 (subunit d, part of the peripheral stalk), ATP8 (subunit 8, part of the peripheral stalk), OLI1 (subunit c, part of the rotor, 10 molecules per monomer), ATP14 (subunit h, part of the peripheral stalk), ATP15 (subunit epsilon, part of the central stalk), ATP16 (subunit delta, part of the central stalk), ATP17 (subunit f, part of the peripheral stalk), ATP18 (subunit i/j, part of the peripheral stalk), ATP19 (subunit k, dimer-specific, at interface between monomers), ATP20 (subunit g, at interface between monomers), TIM11 (subunit e, at interface between monomers) (PubMed:27373333, PubMed:25759169).
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169). F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27373333). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (PubMed:27373333). Part of the complex F(0) domain (PubMed:27373333). Minor subunit located with subunit a/ATP6 in the membrane (PubMed:27373333). Together with subunit e/TIM11, probably contributes to membrane curvature at the site of the ATP synthase dimer, ultimately contributing to formation of cristae (PubMed:27373333).
messages: Mitochondrion inner membrane

284591:YALI0 D15928g
gene id: 284591:YALI0_D15928g
uniprot id: Q6C8Y1
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284591:YALI0 D18381g
gene id: 284591:YALI0_D18381g
uniprot id: Q6C8M9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

284591:YALI0 F13255g
gene id: 284591:YALI0_F13255g
uniprot id: Q6C1U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

284591:YALI0 D23485g
gene id: 284591:YALI0_D23485g
uniprot id: Q6C819
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

284591:YALI0 F14949g
gene id: 284591:YALI0_F14949g
uniprot id: Q6C1M6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E16192g
gene id: 284591:YALI0_E16192g
uniprot id: Q6C5Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1).
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.
messages: Vacuole membrane

284591:YALI0 A18293g
gene id: 284591:YALI0_A18293g
uniprot id: Q6CGL6
names: Similarity
messages: Belongs to the SEN54 family.

284591:YALI0 F14465g
gene id: 284591:YALI0_F14465g
uniprot id: Q6C1P8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

284591:YALI0 A21461g
gene id: 284591:YALI0_A21461g
uniprot id: Q6CG79
names: Similarity
messages: Belongs to the IML2 family.

284591:YALI0 C14960g
gene id: 284591:YALI0_C14960g
uniprot id: Q6CBW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

284591:YALI0 E21912g
gene id: 284591:YALI0_E21912g
uniprot id: P78979
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins and is essential for cell growth. It interacts with other membrane proteins required for protein translocation. Upon binding to SEC62/63 complex, secretory precursor polypeptides may engage SEC61 to begin membrane penetration event. A cycle of assembly and disassembly of SEC62/63 from SEC61 may govern the activity of the translocase (By similarity).
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma.

284591:YALI0 F10505g
gene id: 284591:YALI0_F10505g
uniprot id: Q6C264
names: Similarity
messages: Belongs to the PPP phosphatase family.

284591:YALI0 F25883g
gene id: 284591:YALI0_F25883g
uniprot id: Q6C0C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

284591:YALI0 F07711g
gene id: 284591:YALI0_F07711g
uniprot id: Q6C2I1
names: Function
names: Similarity
messages: Belongs to the GPI family.
messages: In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.

284591:YALI0 F10461g
gene id: 284591:YALI0_F10461g
uniprot id: Q6C266
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

284591:YALI0 B05654g
gene id: 284591:YALI0_B05654g
uniprot id: Q92389
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Secreted

284591:YALI0 B13860g
gene id: 284591:YALI0_B13860g
uniprot id: Q6CEQ5
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 B00264g
gene id: 284591:YALI0_B00264g
uniprot id: Q6CG73
names: Similarity
messages: Belongs to the NifU family.

284591:YALI0 D26884g
gene id: 284591:YALI0_D26884g
uniprot id: Q6C7M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN6 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 F28655g
gene id: 284591:YALI0_F28655g
uniprot id: Q6C012
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Membrane

284591:YALI0 B04268g
gene id: 284591:YALI0_B04268g
uniprot id: Q6CFS5
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. COT1 subfamily.
messages: Protein kinase that seems to play a role in the regulation of cell morphogenesis and proliferation.

284591:YALI0 F07733g
gene id: 284591:YALI0_F07733g
uniprot id: Q6C2I0
names: Function
names: Similarity
messages: Belongs to the peptidase C13 family.
messages: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

284591:YALI0 B02552g
gene id: 284591:YALI0_B02552g
uniprot id: Q6CFY3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E07766g
gene id: 284591:YALI0_E07766g
uniprot id: Q6C6P0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

284591:YALI0 F25531g
gene id: 284591:YALI0_F25531g
uniprot id: Q6C0E1
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

284591:YALI0 E04488g
gene id: 284591:YALI0_E04488g
uniprot id: Q6C719
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

284591:YALI0 C06512g
gene id: 284591:YALI0_C06512g
uniprot id: Q6CCU2
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E18139g
gene id: 284591:YALI0_E18139g
uniprot id: Q6C5G9
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D18854g
gene id: 284591:YALI0_D18854g
uniprot id: Q6C8K7
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

284591:YALI0 C17347g
gene id: 284591:YALI0_C17347g
uniprot id: Q6CBM2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

284591:YALI0 C09904g
gene id: 284591:YALI0_C09904g
uniprot id: Q6CCF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM21 family.
messages: Involved in mitochondrial migration along actin filaments.
messages: actin patch

284591:YALI0 E27291g
gene id: 284591:YALI0_E27291g
uniprot id: Q6C4F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

284591:YALI0 B17820g
gene id: 284591:YALI0_B17820g
uniprot id: Q6CE80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS4/SLD5 family.
messages: Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation (By similarity).

284591:YALI0 A00781g
gene id: 284591:YALI0_A00781g
uniprot id: Q6CI83
names: Similarity
messages: Belongs to the phosducin family.

284591:YALI0 B20856g
gene id: 284591:YALI0_B20856g
uniprot id: Q6CDV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21. Interacts with preproteins in transit (By similarity).
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex (By similarity).
messages: Mitochondrion inner membrane

284591:YALI0 A10010g
gene id: 284591:YALI0_A10010g
uniprot id: Q6CHD5
names: Similarity
messages: Belongs to the PhyH family.

284591:YALI0 F07601g
gene id: 284591:YALI0_F07601g
uniprot id: Q6C2I6
names: Similarity
messages: Belongs to the alpha-actinin family.

284591:YALI0 A09284g
gene id: 284591:YALI0_A09284g
uniprot id: F2Z6D0
names: Function
names: Subunit
messages: Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
messages: Monomer.

284591:YALI0 E12947g
gene id: 284591:YALI0_E12947g
uniprot id: Q6C632
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F30393g
gene id: 284591:YALI0_F30393g
uniprot id: Q6BZW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.
messages: nucleolus

284591:YALI0 C09823g
gene id: 284591:YALI0_C09823g
uniprot id: Q6CCF5
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F14707g
gene id: 284591:YALI0_F14707g
uniprot id: Q6C1N7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284591:YALI0 B00726g
gene id: 284591:YALI0_B00726g
uniprot id: Q6CG56
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.
messages: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.

284591:YALI0 F06160g
gene id: 284591:YALI0_F06160g
uniprot id: Q6C2P6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

284591:YALI0 C08371g
gene id: 284591:YALI0_C08371g
uniprot id: Q6CCL6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A00264g
gene id: 284591:YALI0_A00264g
uniprot id: Q6CIA2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284591:YALI0 D07890g
gene id: 284591:YALI0_D07890g
uniprot id: Q6C9W0
names: Function
names: Similarity
messages: Accepts the ubiquitin-like protein NEDD8/RUB1 from the UBA3-ULA1 E1 complex and catalyzes its covalent attachment to other proteins.
messages: Belongs to the ubiquitin-conjugating enzyme family. UBC12 subfamily.

284591:YALI0 F15213g
gene id: 284591:YALI0_F15213g
uniprot id: Q6C1L4
names: Similarity
messages: Belongs to the CSN12 family.

284591:YALI0 F25553g
gene id: 284591:YALI0_F25553g
uniprot id: Q6C0E0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284591:YALI0 A03025g
gene id: 284591:YALI0_A03025g
uniprot id: Q6CHZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

284591:YALI0 D02321g
gene id: 284591:YALI0_D02321g
uniprot id: Q6CAJ1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

284591:YALI0 E27984g
gene id: 284591:YALI0_E27984g
uniprot id: Q6C4C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

284591:YALI0 A16060g
gene id: 284591:YALI0_A16060g
uniprot id: Q6CGU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Probable transporter.
messages: Vacuole membrane

284591:YALI0 D19206g
gene id: 284591:YALI0_D19206g
uniprot id: Q6C8J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

284591:YALI0 D03663g
gene id: 284591:YALI0_D03663g
uniprot id: Q6CAD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWC3 family.
messages: Nucleus

284591:YALI0 F25619g
gene id: 284591:YALI0_F25619g
uniprot id: Q6C0D7
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C23815g
gene id: 284591:YALI0_C23815g
uniprot id: Q6CAW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: May be involved in cellular response to stress. Required to maintain mitochondrial DNA (mtDNA) integrity and stability (By similarity).
messages: Mitochondrion inner membrane

284591:YALI0 A08239g
gene id: 284591:YALI0_A08239g
uniprot id: Q6CHJ2
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284591:YALI0 B08921g
gene id: 284591:YALI0_B08921g
uniprot id: Q6CFA1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

284591:YALI0 F24959g
gene id: 284591:YALI0_F24959g
uniprot id: Q6C0G4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

284591:YALI0 D02046g
gene id: 284591:YALI0_D02046g
uniprot id: Q6CAK3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F22495g
gene id: 284591:YALI0_F22495g
uniprot id: Q6C0R0
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

284591:YALI0 E33297g
gene id: 284591:YALI0_E33297g
uniprot id: Q6C3P0
names: Similarity
messages: Belongs to the pirin family.

284591:YALI0 C22088g
gene id: 284591:YALI0_C22088g
uniprot id: Q6CB42
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

284591:YALI0 A14784g
gene id: 284591:YALI0_A14784g
uniprot id: Q6CGZ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CybS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 C05951g
gene id: 284591:YALI0_C05951g
uniprot id: Q6CCW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Expected to bind 2 Fe(2+) ions per subunit.
messages: Membrane
messages: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.

284591:YALI0 B20394g
gene id: 284591:YALI0_B20394g
uniprot id: Q6CDX8
names: Similarity
messages: Belongs to the peptidase M24B family.

284591:YALI0 F23727g
gene id: 284591:YALI0_F23727g
uniprot id: Q6C0L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Mitochondrion membrane

284591:YALI0 C22363g
gene id: 284591:YALI0_C22363g
uniprot id: Q6CB29
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C03696g
gene id: 284591:YALI0_C03696g
uniprot id: Q6CD52
names: Similarity
messages: Belongs to the yippee family.

284591:YALI0 E02530g
gene id: 284591:YALI0_E02530g
uniprot id: Q6C7A0
names: Subcellular Location Annotation
messages: Cytoplasm

284591:YALI0 F09449g
gene id: 284591:YALI0_F09449g
uniprot id: Q6C2A4
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

284591:YALI0 D26301g
gene id: 284591:YALI0_D26301g
uniprot id: Q6C7Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Nucleus

284591:YALI0 E35046g
gene id: 284591:YALI0_E35046g
uniprot id: Q6C3G5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

284591:YALI0 B09339g
gene id: 284591:YALI0_B09339g
uniprot id: Q6CF86
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

284591:YALI0 B12166g
gene id: 284591:YALI0_B12166g
uniprot id: Q8TG23
names: Function
names: Similarity
messages: Belongs to the MBF1 family.
messages: Transcriptional coactivator that stimulates transcriptional activity by bridging regulatory proteins and TBP, thereby recruiting TBP to promoters occupied by DNA-binding regulators.

284591:YALI0 F12089g
gene id: 284591:YALI0_F12089g
uniprot id: Q6C1Z6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B22484g
gene id: 284591:YALI0_B22484g
uniprot id: Q6CDN9
names: Similarity
messages: Belongs to the DOCK family.

284591:YALI0 E22220g
gene id: 284591:YALI0_E22220g
uniprot id: Q6C503
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi. Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (By similarity).
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

284591:YALI0 F32021g
gene id: 284591:YALI0_F32021g
uniprot id: Q6BZP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

284591:YALI0 E27203g
gene id: 284591:YALI0_E27203g
uniprot id: Q6C4F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

284591:YALI0 E33935g
gene id: 284591:YALI0_E33935g
uniprot id: Q6C3L1
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

284591:YALI0 C13574g
gene id: 284591:YALI0_C13574g
uniprot id: Q6CC13
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B03784g
gene id: 284591:YALI0_B03784g
uniprot id: Q6CFU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
messages: nucleolus

284591:YALI0 F06138g
gene id: 284591:YALI0_F06138g
uniprot id: Q6C2P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mis12 family.
messages: kinetochore

284591:YALI0 F01122g
gene id: 284591:YALI0_F01122g
uniprot id: Q6C3B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

284591:YALI0 A01980g
gene id: 284591:YALI0_A01980g
uniprot id: Q6CI41
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 F00396g
gene id: 284591:YALI0_F00396g
uniprot id: Q6C3E5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminopeptidase that preferentially cleaves di- and tripeptides. Also has low epoxide hydrolase activity (in vitro). Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 F13343g
gene id: 284591:YALI0_F13343g
uniprot id: Q6C1U3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

284591:YALI0 C12918g
gene id: 284591:YALI0_C12918g
uniprot id: Q6CC34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 F07931g
gene id: 284591:YALI0_F07931g
uniprot id: Q6C2H1
names: Similarity
messages: Belongs to the SMP-30/CGR1 family.

284591:YALI0 B02794g
gene id: 284591:YALI0_B02794g
uniprot id: Q6CFX4
names: Similarity
messages: Belongs to the peptidase S8 family.

284591:YALI0 B02244g
gene id: 284591:YALI0_B02244g
uniprot id: Q6CFZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Golgi apparatus membrane
messages: Membrane

284591:YALI0 D23133g
gene id: 284591:YALI0_D23133g
uniprot id: Q6C835
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284591:YALI0 A10659g
gene id: 284591:YALI0_A10659g
uniprot id: F2Z5Z3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer.

284591:YALI0 E02376g
gene id: 284591:YALI0_E02376g
uniprot id: Q6C7A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

284591:YALI0 F01793g
gene id: 284591:YALI0_F01793g
uniprot id: Q6C386
names: Subcellular Location Annotation
messages: Cytoplasm

284591:YALI0 B22880g
gene id: 284591:YALI0_B22880g
uniprot id: Q6CDM1
names: Similarity
messages: Belongs to the peptidase S8 family.

284591:YALI0 A20680g
gene id: 284591:YALI0_A20680g
uniprot id: Q6CGB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Mitochondrion inner membrane

284591:YALI0 F07040g
gene id: 284591:YALI0_F07040g
uniprot id: Q6C2K8
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C09801g
gene id: 284591:YALI0_C09801g
uniprot id: Q6CCF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Mitochondrion inner membrane
messages: Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.

284591:YALI0 D02959g
gene id: 284591:YALI0_D02959g
uniprot id: Q6CAG4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM10 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. Associates with the mitochondrial outer membrane sorting assembly machinery SAM(core) complex.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
messages: Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.
messages: Mitochondrion outer membrane

284591:YALI0 D00275g
gene id: 284591:YALI0_D00275g
uniprot id: Q6CAS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

284591:YALI0 F06512g
gene id: 284591:YALI0_F06512g
uniprot id: Q6C2M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 A18007g
gene id: 284591:YALI0_A18007g
uniprot id: Q6CGM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: nucleoplasm

284591:YALI0 F00264g
gene id: 284591:YALI0_F00264g
uniprot id: Q6C3F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 B16566g
gene id: 284591:YALI0_B16566g
uniprot id: Q6CED3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

284591:YALI0 C23342g
gene id: 284591:YALI0_C23342g
uniprot id: Q6CAY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

284591:YALI0 F25135g
gene id: 284591:YALI0_F25135g
uniprot id: F2Z699
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane.
messages: Belongs to the NADH dehydrogenase family.
messages: Binds 1 FAD per subunit.
messages: Mitochondrion inner membrane

284591:YALI0 E24145g
gene id: 284591:YALI0_E24145g
uniprot id: Q6C4S3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C14322g
gene id: 284591:YALI0_C14322g
uniprot id: Q6CBY9
names: Similarity
messages: Belongs to the PrpF family.

284591:YALI0 B17512g
gene id: 284591:YALI0_B17512g
uniprot id: Q99161
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Part of a complex that contains SEC61, SEC62, SEC63, SEC66 and SEC72.
messages: Required for preprotein translocation.

284591:YALI0 F11121g
gene id: 284591:YALI0_F11121g
uniprot id: Q6C239
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FES1 family.
messages: Cytoplasm
messages: Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins (By similarity).

284591:YALI0 B15400g
gene id: 284591:YALI0_B15400g
uniprot id: Q6CEI3
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

284591:YALI0 D23309g
gene id: 284591:YALI0_D23309g
uniprot id: Q6C827
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

284591:YALI0 D14982g
gene id: 284591:YALI0_D14982g
uniprot id: Q6C922
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
messages: Nucleus

284591:YALI0 D21076g
gene id: 284591:YALI0_D21076g
uniprot id: Q6C8B4
names: Similarity
messages: Belongs to the FMO family.

284591:YALI0 A16445g
gene id: 284591:YALI0_A16445g
uniprot id: Q6CGT2
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

284591:YALI0 F28281g
gene id: 284591:YALI0_F28281g
uniprot id: Q6C029
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

284591:YALI0 D27258g
gene id: 284591:YALI0_D27258g
uniprot id: Q6C7K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF1 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus

284591:YALI0 F09603g
gene id: 284591:YALI0_F09603g
uniprot id: Q6C297
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

284591:YALI0 A06611g
gene id: 284591:YALI0_A06611g
uniprot id: Q6CHP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCM1 family.
messages: Mitochondrion
messages: RNA-binding protein involved in the specific removal of group I introns in mitochondrial encoded transcripts. Maintains the stability of the small subunit mitochondrial 15S rRNA and thus the expression of the mitochondrial genome (By similarity).

284591:YALI0 E12463g
gene id: 284591:YALI0_E12463g
uniprot id: Q6C648
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

284591:YALI0 E34551g
gene id: 284591:YALI0_E34551g
uniprot id: Q6C3I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

284591:YALI0 E25069g
gene id: 284591:YALI0_E25069g
uniprot id: Q6C4N2
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A04345g
gene id: 284591:YALI0_A04345g
uniprot id: Q6CHW0
names: Similarity
messages: Belongs to the CDC73 family.

284591:YALI0 F21967g
gene id: 284591:YALI0_F21967g
uniprot id: Q6C0T2
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.

284591:YALI0 F04708g
gene id: 284591:YALI0_F04708g
uniprot id: Q6C2V9
names: Similarity
messages: Belongs to the SURF6 family.

284591:YALI0 B14553g
gene id: 284591:YALI0_B14553g
uniprot id: Q6CEM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

284591:YALI0 D25828g
gene id: 284591:YALI0_D25828g
uniprot id: Q6C7S1
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F17666g
gene id: 284591:YALI0_F17666g
uniprot id: Q6C1B6
names: Similarity
messages: Belongs to the COG3 family.

284591:YALI0 E27715g
gene id: 284591:YALI0_E27715g
uniprot id: Q6C4D4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing.
messages: Associates with polysomes.
messages: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
messages: Cytoplasm
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284591:YALI0 D24233g
gene id: 284591:YALI0_D24233g
uniprot id: Q6C7Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

284591:YALI0 D25036g
gene id: 284591:YALI0_D25036g
uniprot id: Q6C7V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking.

284591:YALI0 C23947g
gene id: 284591:YALI0_C23947g
uniprot id: Q6CAV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

284591:YALI0 E00770g
gene id: 284591:YALI0_E00770g
uniprot id: Q6C7H6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

284591:YALI0 A08998g
gene id: 284591:YALI0_A08998g
uniprot id: F2Z653
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 F10725g
gene id: 284591:YALI0_F10725g
uniprot id: Q6C255
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

284591:YALI0 B14905g
gene id: 284591:YALI0_B14905g
uniprot id: Q6CEK7
names: Similarity
messages: Belongs to the RNase PH family.

284591:YALI0 A17512g
gene id: 284591:YALI0_A17512g
uniprot id: Q6CGP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 D09449g
gene id: 284591:YALI0_D09449g
uniprot id: Q6C9P3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity).
messages: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284591:YALI0 F07777g
gene id: 284591:YALI0_F07777g
uniprot id: Q6C2H8
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 D20592g
gene id: 284591:YALI0_D20592g
uniprot id: Q6C8D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

284591:YALI0 D19140g
gene id: 284591:YALI0_D19140g
uniprot id: Q6C8J4
names: Similarity
messages: Belongs to the malate synthase family.

284591:YALI0 D20966g
gene id: 284591:YALI0_D20966g
uniprot id: Q6C8B8
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

284591:YALI0 C16819g
gene id: 284591:YALI0_C16819g
uniprot id: Q6CBP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

284591:YALI0 E04114g
gene id: 284591:YALI0_E04114g
uniprot id: Q6C734
names: Similarity
messages: Belongs to the MUB1/samB family.

284591:YALI0 D24651g
gene id: 284591:YALI0_D24651g
uniprot id: Q6C7X0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B08140g
gene id: 284591:YALI0_B08140g
uniprot id: Q6CFD3
names: Similarity
messages: Belongs to the PAPS reductase family. CysH subfamily.

284591:YALI0 A20108g
gene id: 284591:YALI0_A20108g
uniprot id: Q6CGE0
names: Similarity
messages: In the C-terminal section; belongs to the NAD synthetase family.

284591:YALI0 F00902g
gene id: 284591:YALI0_F00902g
uniprot id: Q6C3C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRT14 family.
messages: Involved in ribosome biogenesis, probably through modulation of rDNA transcription.
messages: nucleolus

284591:YALI0 E06897g
gene id: 284591:YALI0_E06897g
uniprot id: Q6C6R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284591:YALI0 A09856g
gene id: 284591:YALI0_A09856g
uniprot id: Q6CHE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

284591:YALI0 E10725g
gene id: 284591:YALI0_E10725g
uniprot id: Q6C6C0
names: Similarity
messages: Belongs to the RNase H family.

284591:YALI0 E25091g
gene id: 284591:YALI0_E25091g
uniprot id: Q6C4N1
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

284591:YALI0 B12584g
gene id: 284591:YALI0_B12584g
uniprot id: Q6CEV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enhancer of polycomb family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M (By similarity).
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus

284591:YALI0 A15147g
gene id: 284591:YALI0_A15147g
uniprot id: Q6CGX5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

284591:YALI0 B00924g
gene id: 284591:YALI0_B00924g
uniprot id: Q6CG47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP46 family.
messages: Mitochondrion
messages: Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules.

284591:YALI0 F18854g
gene id: 284591:YALI0_F18854g
uniprot id: Q6C165
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 E11957g
gene id: 284591:YALI0_E11957g
uniprot id: Q6C671
names: Similarity
messages: Belongs to the CMC family.

284591:YALI0 E34375g
gene id: 284591:YALI0_E34375g
uniprot id: Q6C3J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: Nucleus
messages: Required for high-fidelity chromosome segregation during the later part of each cell cycle. Acts in opposition to the phosphatase PP1. Has a role in attaching the kinetochores to the microtubules and ensuring that sister kinetochores connect to opposite poles. The promotion of bi-orientation is achieved by selectively detaching kinetochore-microtubule attachments that are not under tension (By similarity).
messages: kinetochore
messages: spindle

284591:YALI0 E21648g
gene id: 284591:YALI0_E21648g
uniprot id: Q6C524
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Component of the 20S proteasome chaperone.
messages: Involved in 20S proteasome assembly.

284591:YALI0 B01782g
gene id: 284591:YALI0_B01782g
uniprot id: Q6CG13
names: Similarity
messages: Belongs to the peptidase S33 family.

284591:YALI0 F25817g
gene id: 284591:YALI0_F25817g
uniprot id: Q6C0C8
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

284591:YALI0 E22022g
gene id: 284591:YALI0_E22022g
uniprot id: Q6C509
names: Similarity
messages: Belongs to the PAF1 family.

284591:YALI0 C17105g
gene id: 284591:YALI0_C17105g
uniprot id: Q6CBM9
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B11704g
gene id: 284591:YALI0_B11704g
uniprot id: Q6CEZ2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

284591:YALI0 C16005g
gene id: 284591:YALI0_C16005g
uniprot id: Q6CBS4
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 D08184g
gene id: 284591:YALI0_D08184g
uniprot id: Q6C9V0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

284591:YALI0 D19910g
gene id: 284591:YALI0_D19910g
uniprot id: Q6C8G3
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the peptidase M67A family.

284591:YALI0 F16874g
gene id: 284591:YALI0_F16874g
uniprot id: Q6C1F1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

284591:YALI0 F12353g
gene id: 284591:YALI0_F12353g
uniprot id: Q6C1Y5
names: Similarity
messages: Belongs to the peptidase S14 family.

284591:YALI0 D18744g
gene id: 284591:YALI0_D18744g
uniprot id: Q6C8L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 C15895g
gene id: 284591:YALI0_C15895g
uniprot id: Q6CBS7
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

284591:YALI0 C19283g
gene id: 284591:YALI0_C19283g
uniprot id: Q6CBF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

284591:YALI0 F02409g
gene id: 284591:YALI0_F02409g
uniprot id: Q6C358
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

284591:YALI0 F10197g
gene id: 284591:YALI0_F10197g
uniprot id: Q6C273
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

284591:YALI0 F18084g
gene id: 284591:YALI0_F18084g
uniprot id: Q6C1A0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284591:YALI0 D13750g
gene id: 284591:YALI0_D13750g
uniprot id: Q6C961
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Nucleus
messages: Possesses 5'->3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote termination of transcription by RNA polymerase II (By similarity).

284591:YALI0 C24123g
gene id: 284591:YALI0_C24123g
uniprot id: Q6CAV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

284591:YALI0 B14124g
gene id: 284591:YALI0_B14124g
uniprot id: Q6CEP3
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

284591:YALI0 D26510g
gene id: 284591:YALI0_D26510g
uniprot id: Q6C7P2
names: Similarity
messages: Belongs to the epsin family.

284591:YALI0 F23309g
gene id: 284591:YALI0_F23309g
uniprot id: Q6C0M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the NTC complex (or PRP19-associated complex). The NTC complex associates with the spliceosome after the release of the U1 and U4 snRNAs and forms the CWC spliceosome subcomplex reminiscent of a late-stage spliceosome.
messages: Belongs to the CWC21 family.
messages: Cytoplasm
messages: Involved in pre-mRNA splicing. May function at or prior to the first catalytic step of splicing at the catalytic center of the spliceosome. May do so by stabilizing the catalytic center or the position of the RNA substrate (By similarity).
messages: Nucleus

284591:YALI0 F16005g
gene id: 284591:YALI0_F16005g
uniprot id: Q6C1I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

284591:YALI0 F31141g
gene id: 284591:YALI0_F31141g
uniprot id: Q6BZT0
names: Similarity
messages: Belongs to the HIT family.

284591:YALI0 D12925g
gene id: 284591:YALI0_D12925g
uniprot id: Q6C995
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

284591:YALI0 C15345g
gene id: 284591:YALI0_C15345g
uniprot id: B5FVC7
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E24893g
gene id: 284591:YALI0_E24893g
uniprot id: Q6C4P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

284591:YALI0 F18370g
gene id: 284591:YALI0_F18370g
uniprot id: Q6C187
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns (By similarity).
messages: Nucleus

284591:YALI0 A03861g
gene id: 284591:YALI0_A03861g
uniprot id: Q6CHX2
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

284591:YALI0 A18183g
gene id: 284591:YALI0_A18183g
uniprot id: Q6CGM1
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F16357g
gene id: 284591:YALI0_F16357g
uniprot id: Q6C1G9
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

284591:YALI0 E24959g
gene id: 284591:YALI0_E24959g
uniprot id: Q6C4N7
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C04774g
gene id: 284591:YALI0_C04774g
uniprot id: Q6CD10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

284591:YALI0 A06479g
gene id: 284591:YALI0_A06479g
uniprot id: Q6CHQ3
names: Subcellular Location Annotation
messages: nucleolus

284591:YALI0 A18205g
gene id: 284591:YALI0_A18205g
uniprot id: Q6CGM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with RPS21.
messages: Cytoplasm
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.

284591:YALI0 E06435g
gene id: 284591:YALI0_E06435g
uniprot id: Q6C6T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.
messages: Belongs to the CNOT2/3/5 family.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 F28589g
gene id: 284591:YALI0_F28589g
uniprot id: Q6C015
names: Similarity
messages: Belongs to the CoA-transferase III family.

284591:YALI0 B17864g
gene id: 284591:YALI0_B17864g
uniprot id: Q6CE78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Membrane

284591:YALI0 B08030g
gene id: 284591:YALI0_B08030g
uniprot id: Q96VC9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

284591:YALI0 D20152g
gene id: 284591:YALI0_D20152g
uniprot id: Q6C8F2
names: Similarity
messages: Belongs to the acetyltransferase family. GNA1 subfamily.

284591:YALI0 F02299g
gene id: 284591:YALI0_F02299g
uniprot id: Q6C363
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284591:YALI0 D03179g
gene id: 284591:YALI0_D03179g
uniprot id: Q6CAF6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F26169g
gene id: 284591:YALI0_F26169g
uniprot id: Q6C0B5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer or homoheptamer. Organized in a ring with a central cavity.
messages: Mitochondrion matrix
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

284591:YALI0 F26136g
gene id: 284591:YALI0_F26136g
uniprot id: B5RSM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2), composed of at least SUS1, SAC3, THP1, SEM1, and CDC31. TREX-2 contains 2 SUS1 chains. The TREX-2 complex interacts with the nucleoporin NUP1. Component of the 1.8 MDa SAGA transcription coactivator-HAT complex. SAGA is built of 5 distinct domains with specialized functions. Within the SAGA complex, SUS1, SGF11, SGF73 and UBP8 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with THP1, SAC3, SGF11, and with the RNA polymerase II.
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies (By similarity).
messages: P-body
messages: nucleoplasm

284591:YALI0 F07381g
gene id: 284591:YALI0_F07381g
uniprot id: Q6C2J4
names: Similarity
messages: Belongs to the VPS52 family.

284591:YALI0 F06182g
gene id: 284591:YALI0_F06182g
uniprot id: Q6C2P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: nucleolus

284591:YALI0 C01133g
gene id: 284591:YALI0_C01133g
uniprot id: Q6CDE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: May be involved in vacuolar sorting and osmoregulation.
messages: Vacuole membrane

284591:YALI0 B01562g
gene id: 284591:YALI0_B01562g
uniprot id: Q6CG22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pym family.
messages: Cytoplasm

284591:YALI0 F00374g
gene id: 284591:YALI0_F00374g
uniprot id: Q6C3E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histone H4 family.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

284591:YALI0 D11066g
gene id: 284591:YALI0_D11066g
uniprot id: Q6C9H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 D22330g
gene id: 284591:YALI0_D22330g
uniprot id: Q6C865
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

284591:YALI0 B11880g
gene id: 284591:YALI0_B11880g
uniprot id: Q6CEY4
names: Similarity
messages: Belongs to the BRX1 family.

284591:YALI0 E21241g
gene id: 284591:YALI0_E21241g
uniprot id: Q6C539
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E24387g
gene id: 284591:YALI0_E24387g
uniprot id: Q6C4R2
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E34980g
gene id: 284591:YALI0_E34980g
uniprot id: Q6C3G7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

284591:YALI0 E17391g
gene id: 284591:YALI0_E17391g
uniprot id: Q6C5K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14 (By similarity).

284591:YALI0 A11781g
gene id: 284591:YALI0_A11781g
uniprot id: Q6CH71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

284591:YALI0 E16951g
gene id: 284591:YALI0_E16951g
uniprot id: Q6C5L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2H phosphoesterase superfamily. USB1 family.
messages: Nucleus
messages: Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA.

284591:YALI0 B04004g
gene id: 284591:YALI0_B04004g
uniprot id: W0TYN6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F00660g
gene id: 284591:YALI0_F00660g
uniprot id: Q6C3D3
names: Similarity
messages: Belongs to the HTATSF1 family.

284591:YALI0 E10923g
gene id: 284591:YALI0_E10923g
uniprot id: Q6C6B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport.

284591:YALI0 A09636g
gene id: 284591:YALI0_A09636g
uniprot id: Q6CHE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.

284591:YALI0 E27005g
gene id: 284591:YALI0_E27005g
uniprot id: Q6C4G4
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

284591:YALI0 C14058g
gene id: 284591:YALI0_C14058g
uniprot id: Q6CBZ6
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 D04719g
gene id: 284591:YALI0_D04719g
uniprot id: Q6CA98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus
messages: Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex.

284591:YALI0 D08954g
gene id: 284591:YALI0_D08954g
uniprot id: Q6C9R5
names: Subcellular Location Annotation
messages: nuclear pore complex

284591:YALI0 C23749g
gene id: 284591:YALI0_C23749g
uniprot id: Q6CAW8
names: Similarity
messages: Belongs to the AAA ATPase family.

284591:YALI0 B17226g
gene id: 284591:YALI0_B17226g
uniprot id: Q6CEA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Endoplasmic reticulum membrane

284591:YALI0 E23760g
gene id: 284591:YALI0_E23760g
uniprot id: Q6C4T8
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

284591:YALI0 C07909g
gene id: 284591:YALI0_C07909g
uniprot id: Q6CCN6
names: Similarity
messages: Belongs to the Tango6 family.

284591:YALI0 D25630g
gene id: 284591:YALI0_D25630g
uniprot id: Q6C7T0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

284591:YALI0 C17083g
gene id: 284591:YALI0_C17083g
uniprot id: Q6CBN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

284591:YALI0 B06391g
gene id: 284591:YALI0_B06391g
uniprot id: Q6CFJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 E31779g
gene id: 284591:YALI0_E31779g
uniprot id: Q6C3V9
names: Function
names: Similarity
messages: Belongs to the TYW1 family.
messages: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.

284591:YALI0 D00957g
gene id: 284591:YALI0_D00957g
uniprot id: Q6CAP8
names: Similarity
messages: Belongs to the KRI1 family.

284591:YALI0 E33209g
gene id: 284591:YALI0_E33209g
uniprot id: Q6C3P4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues (By similarity).

284591:YALI0 A20130g
gene id: 284591:YALI0_A20130g
uniprot id: Q6CGD9
names: Similarity
messages: Belongs to the cytochrome P450 family.

284591:YALI0 A16819g
gene id: 284591:YALI0_A16819g
uniprot id: Q6CGR8
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 B12452g
gene id: 284591:YALI0_B12452g
uniprot id: Q6CEW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

284591:YALI0 B01672g
gene id: 284591:YALI0_B01672g
uniprot id: Q6CG17
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

284591:YALI0 B05214g
gene id: 284591:YALI0_B05214g
uniprot id: Q6CFP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

284591:YALI0 E18546g
gene id: 284591:YALI0_E18546g
uniprot id: Q6C5F4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

284591:YALI0 B11682g
gene id: 284591:YALI0_B11682g
uniprot id: Q6CEZ3
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

284591:YALI0 E26235g
gene id: 284591:YALI0_E26235g
uniprot id: Q6C4J6
names: Similarity
messages: Belongs to the UFD1 family.

284591:YALI0 D27126g
gene id: 284591:YALI0_D27126g
uniprot id: Q6C7L4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: The active site is a redox-active disulfide bond.

284591:YALI0 C19217g
gene id: 284591:YALI0_C19217g
uniprot id: Q6CBF9
names: Similarity
messages: Belongs to the DCC1 family.

284591:YALI0 E23287g
gene id: 284591:YALI0_E23287g
uniprot id: Q6C4W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 E32307g
gene id: 284591:YALI0_E32307g
uniprot id: Q6C3T3
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 C20317g
gene id: 284591:YALI0_C20317g
uniprot id: Q6CBB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Heterodimers with GPN1 or GPN2. Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

284591:YALI0 B15818g
gene id: 284591:YALI0_B15818g
uniprot id: Q6CEG5
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 D16203g
gene id: 284591:YALI0_D16203g
uniprot id: Q6C8X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

284591:YALI0 F04015g
gene id: 284591:YALI0_F04015g
uniprot id: Q6C2Y8
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

284591:YALI0 D13464g
gene id: 284591:YALI0_D13464g
uniprot id: Q6C974
names: Subcellular Location Annotation
messages: nucleolus

284591:YALI0 F21109g
gene id: 284591:YALI0_F21109g
uniprot id: Q6C0W8
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D04873g
gene id: 284591:YALI0_D04873g
uniprot id: Q6CA91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

284591:YALI0 B07029g
gene id: 284591:YALI0_B07029g
uniprot id: Q6CFH0
names: Similarity
messages: Belongs to the WrbA family.

284591:YALI0 D21890g
gene id: 284591:YALI0_D21890g
uniprot id: Q6C883
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

284591:YALI0 E13662g
gene id: 284591:YALI0_E13662g
uniprot id: Q6C601
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.

284591:YALI0 B14861g
gene id: 284591:YALI0_B14861g
uniprot id: Q6CEK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mitochondrion inner membrane

284591:YALI0 E31317g
gene id: 284591:YALI0_E31317g
uniprot id: Q6C3Y2
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

284591:YALI0 F01166g
gene id: 284591:YALI0_F01166g
uniprot id: Q6C3B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
messages: Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization.
messages: Endoplasmic reticulum membrane

284591:YALI0 F26543g
gene id: 284591:YALI0_F26543g
uniprot id: Q6C0A0
names: Similarity
messages: Belongs to the RNase H family.

284591:YALI0 F24563g
gene id: 284591:YALI0_F24563g
uniprot id: F2Z686
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

284591:YALI0 F11253g
gene id: 284591:YALI0_F11253g
uniprot id: Q6C233
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SQS1 family.
messages: Cytoplasm
messages: May be involved in splicing.
messages: Nucleus

284591:YALI0 C06820g
gene id: 284591:YALI0_C06820g
uniprot id: Q6CCT0
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

284591:YALI0 B19602g
gene id: 284591:YALI0_B19602g
uniprot id: Q6CE10
names: Similarity
messages: Belongs to the EFG1/PHD1/stuA family.

284591:YALI0 E02068g
gene id: 284591:YALI0_E02068g
uniprot id: Q6C7B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ku80 family.
messages: Heterodimer of Ku70 and Ku80.
messages: Nucleus
messages: Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. Involved in telomere maintenance. Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement. Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere. Required for mating-type switching (By similarity).
messages: telomere

284591:YALI0 D19580g
gene id: 284591:YALI0_D19580g
uniprot id: Q6C8H4
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

284591:YALI0 E26455g
gene id: 284591:YALI0_E26455g
uniprot id: Q6C4I7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated by GCN5 to form H2BK11ac and H2BK16ac. H2BK16ac can also be formed by ESA1. Acetylation of N-terminal lysines and particularly formation of H2BK11acK16ac has a positive effect on transcription (By similarity).
messages: Belongs to the histone H2B family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Monoubiquitinated by the UBC2-BRE1 complex to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for H3K4me and H3K79me formation. H2BK123ub1 also modulates the formation of double-strand breaks during meiosis and is a prerequisite for DNA-damage checkpoint activation (By similarity).
messages: Nucleus
messages: Sumoylation to form H2BK6su or H2BK7su, and probably also H2BK16su or H2BK17su, occurs preferentially near the telomeres and represses gene transcription.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H2BK6ac = acetylated Lys-8; H2BK6su = sumoylated Lys-8; H2BK7ac = acetylated Lys-9; H2BK7su = sumoylated Lys-9; H2BK11ac = acetylated Lys-15; H2BK16ac = acetylated Lys-25; H2BK16su = sumoylated Lys-25; H2BK17su = sumoylated Lys-26; H2BK123ub1 = monoubiquitinated Lys-133.

284591:YALI0 C12749g
gene id: 284591:YALI0_C12749g
uniprot id: Q6CC39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Binds 1 zinc ion per subunit.
messages: Formation of pseudouridine at positions 27 and 28 in the anticodon stem and loop of transfer RNAs; at positions 34 and 36 of intron-containing precursor tRNA(Ile) and at position 35 in the intron-containing tRNA(Tyr). Catalyzes pseudouridylation at position 44 in U2 snRNA. Also catalyzes pseudouridylation of mRNAs.
messages: Nucleus

284591:YALI0 F22055g
gene id: 284591:YALI0_F22055g
uniprot id: Q6C0S8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1.
messages: Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.
messages: Cytoplasm

284591:YALI0 E33165g
gene id: 284591:YALI0_E33165g
uniprot id: Q6C3P6
names: Similarity
messages: Belongs to the syntaxin family.

284591:YALI0 A06743g
gene id: 284591:YALI0_A06743g
uniprot id: Q6CHP3
names: Similarity
messages: Belongs to the GST superfamily.

284591:YALI0 E24299g
gene id: 284591:YALI0_E24299g
uniprot id: Q6C4R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

284591:YALI0 F10153g
gene id: 284591:YALI0_F10153g
uniprot id: Q6C275
names: Similarity
messages: Belongs to the TTC4 family.

284591:YALI0 B05500g
gene id: 284591:YALI0_B05500g
uniprot id: Q6CFN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

284591:YALI0 D09867g
gene id: 284591:YALI0_D09867g
uniprot id: Q6C9M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
messages: Mitochondrion outer membrane

284591:YALI0 F22429g
gene id: 284591:YALI0_F22429g
uniprot id: Q6C0R3
names: Similarity
messages: Belongs to the TMEM14 family.

284591:YALI0 F30415g
gene id: 284591:YALI0_F30415g
uniprot id: Q6BZW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Involved in vacuolar transport and vacuole pH homeostasis. Also required for cytokinesis (By similarity).
messages: Vacuole membrane

284591:YALI0 E06519g
gene id: 284591:YALI0_E06519g
uniprot id: W0TYM1
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

284591:YALI0 B06303g
gene id: 284591:YALI0_B06303g
uniprot id: Q6CFJ9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

284591:YALI0 B16412g
gene id: 284591:YALI0_B16412g
uniprot id: Q6CEE0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E15818g
gene id: 284591:YALI0_E15818g
uniprot id: Q6C5R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

284591:YALI0 E15840g
gene id: 284591:YALI0_E15840g
uniprot id: Q6C5R4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284591:YALI0 D19118g
gene id: 284591:YALI0_D19118g
uniprot id: Q6C8J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 E13618g
gene id: 284591:YALI0_E13618g
uniprot id: Q6C603
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

284591:YALI0 D17776g
gene id: 284591:YALI0_D17776g
uniprot id: Q6C8Q7
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

284591:YALI0 F17556g
gene id: 284591:YALI0_F17556g
uniprot id: Q6C1C1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

284591:YALI0 E05313g
gene id: 284591:YALI0_E05313g
uniprot id: Q6C6Y3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A08932g
gene id: 284591:YALI0_A08932g
uniprot id: Q6CHG3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

284591:YALI0 D00176g
gene id: 284591:YALI0_D00176g
uniprot id: Q6CAT3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

284591:YALI0 D19096g
gene id: 284591:YALI0_D19096g
uniprot id: Q6C8J6
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

284591:YALI0 E26477g
gene id: 284591:YALI0_E26477g
uniprot id: Q6C4I6
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated by ESA1 to form H2AK4ac and H2AK7ac.
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: In contrast to vertebrates and insects, its C-terminus is not monoubiquitinated.
messages: Nucleus
messages: Phosphorylated to form H2AS128ph (gamma-H2A) in response to DNA double-strand breaks (DSBs) generated by exogenous genotoxic agents and by stalled replication forks. Phosphorylation is dependent on the DNA damage checkpoint kinases MEC1/ATR and TEL1/ATM, spreads on either side of a detected DSB site and may mark the surrounding chromatin for recruitment of proteins required for DNA damage signaling and repair. Gamma-H2A is removed from the DNA prior to the strand invasion-primer extension step of the repair process and subsequently dephosphorylated. Dephosphorylation is necessary for efficient recovery from the DNA damage checkpoint (By similarity).
messages: The [ST]-Q motif constitutes a recognition sequence for kinases from the PI3/PI4-kinase family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H2AK4ac = acetylated Lys-6; H2AK7ac = acetylated Lys-10; H2AS128ph = phosphorylated Ser-132.

284591:YALI0 B03410g
gene id: 284591:YALI0_B03410g
uniprot id: Q6CFV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHE3 family.
messages: Endoplasmic reticulum membrane
messages: RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Required for the delivery of cortical endoplasmic reticulum into the emerging bud.

284591:YALI0 D22000g
gene id: 284591:YALI0_D22000g
uniprot id: Q6C878
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D20570g
gene id: 284591:YALI0_D20570g
uniprot id: Q6C8D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

284591:YALI0 B18700g
gene id: 284591:YALI0_B18700g
uniprot id: Q6CE43
names: Similarity
messages: Belongs to the protein kinase superfamily.

284591:YALI0 D15356g
gene id: 284591:YALI0_D15356g
uniprot id: Q6C905
names: Similarity
messages: Belongs to the CBF/MAK21 family.

284591:YALI0 D11125g
gene id: 284591:YALI0_D11125g
uniprot id: B5FVE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

284591:YALI0 D03916g
gene id: 284591:YALI0_D03916g
uniprot id: Q6CAD1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrion-specific ribosomal protein mS23 family.
messages: Component of the mitochondrial small ribosomal subunit.
messages: Mitochondrion

284591:YALI0 E02090g
gene id: 284591:YALI0_E02090g
uniprot id: Q6C7B8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

284591:YALI0 E05049g
gene id: 284591:YALI0_E05049g
uniprot id: Q6C6Z5
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

284591:YALI0 E01144g
gene id: 284591:YALI0_E01144g
uniprot id: Q6C7F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM31/MDM32 family.
messages: Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.
messages: Mitochondrion inner membrane

284591:YALI0 B05830g
gene id: 284591:YALI0_B05830g
uniprot id: Q6CFL6
names: Similarity
messages: Belongs to the dpy-30 family.

284591:YALI0 C16907g
gene id: 284591:YALI0_C16907g
uniprot id: Q6CBN8
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F17072g
gene id: 284591:YALI0_F17072g
uniprot id: Q6C1E2
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.

284591:YALI0 C14036g
gene id: 284591:YALI0_C14036g
uniprot id: Q6CBZ7
names: Similarity
messages: Belongs to the taffazin family.

284591:YALI0 F01672g
gene id: 284591:YALI0_F01672g
uniprot id: Q6C391
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

284591:YALI0 D07524g
gene id: 284591:YALI0_D07524g
uniprot id: Q6C9X7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: GTPase-activating protein for the ADP ribosylation factor family.

284591:YALI0 C16731g
gene id: 284591:YALI0_C16731g
uniprot id: Q6CBP6
names: Similarity
messages: Belongs to the PET191 family.

284591:YALI0 F17446g
gene id: 284591:YALI0_F17446g
uniprot id: Q6C1C6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B11330g
gene id: 284591:YALI0_B11330g
uniprot id: F2Z6G2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

284591:YALI0 C11605g
gene id: 284591:YALI0_C11605g
uniprot id: Q6CC82
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Facilitates protein transport into the nucleus. Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import (By similarity).

284591:YALI0 D01980g
gene id: 284591:YALI0_D01980g
uniprot id: Q6CAK6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284591:YALI0 A20328g
gene id: 284591:YALI0_A20328g
uniprot id: Q6CGD1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase required for ribosome biogenesis. Involved in the release of U14 snoRNA in pre-ribosomal complexes. Required for pre-rRNA cleavage at site A2 (By similarity).
messages: Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily.
messages: Interacts with the U3 and U14 snoRNAs. Associates with pre-ribosomal complexes (By similarity).
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284591:YALI0 B20922g
gene id: 284591:YALI0_B20922g
uniprot id: Q6CDV4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: Component of the eIF4F complex, which composition varies with external and internal environmental conditions. It is composed of at least eIF4A, eIF4E and eIF4G (By similarity).
messages: Cytoplasm
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284591:YALI0 F25663g
gene id: 284591:YALI0_F25663g
uniprot id: Q6C0D5
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 B04180g
gene id: 284591:YALI0_B04180g
uniprot id: Q6CFS9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Mitochondrion
messages: Monomer.

284591:YALI0 B08624g
gene id: 284591:YALI0_B08624g
uniprot id: Q6CFB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates 60S ribosomal protein L42.

284591:YALI0 D27148g
gene id: 284591:YALI0_D27148g
uniprot id: Q6C7L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

284591:YALI0 C18755g
gene id: 284591:YALI0_C18755g
uniprot id: Q6CBH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Assembly of polyisoprenoid side chains. The polyprenyl synthase of coenzyme Q biosynthesis catalyzes the formation from isopentenyl diphosphate of all trans-polyprenyl pyrophosphates generally ranging in length of between 6 and 10 isoprene units depending on the species (By similarity).
messages: Belongs to the FPP/GGPP synthase family.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Mitochondrion

284591:YALI0 B15884g
gene id: 284591:YALI0_B15884g
uniprot id: Q6CEG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

284591:YALI0 A17490g
gene id: 284591:YALI0_A17490g
uniprot id: Q6CGP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ING family.
messages: Nucleus

284591:YALI0 D22979g
gene id: 284591:YALI0_D22979g
uniprot id: Q6C840
names: Similarity
messages: Belongs to the TEL2 family.

284591:YALI0 D08470g
gene id: 284591:YALI0_D08470g
uniprot id: Q6C9T7
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

284591:YALI0 F07755g
gene id: 284591:YALI0_F07755g
uniprot id: Q6C2H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C1D family.
messages: Nucleus
messages: Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites.

284591:YALI0 E16995g
gene id: 284591:YALI0_E16995g
uniprot id: Q6C5L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: The COPII coat is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex, and the protein SAR1.

284591:YALI0 C10516g
gene id: 284591:YALI0_C10516g
uniprot id: Q6CCD0
names: Similarity
messages: Belongs to the cyclin family.

284591:YALI0 C20119g
gene id: 284591:YALI0_C20119g
uniprot id: Q6CBC3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG7 family.
messages: Cytoplasm
messages: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Plays a role in the regulation of filamentous growth and chronological longevity (By similarity).
messages: Homodimer.
messages: Preautophagosomal structure
messages: The GxGxxG motif is important for the function, possibly through binding with ATP.

284591:YALI0 E14509g
gene id: 284591:YALI0_E14509g
uniprot id: Q6C5W7
names: Similarity
messages: Belongs to the cytochrome P450 family.

284591:YALI0 E02904g
gene id: 284591:YALI0_E02904g
uniprot id: Q6C783
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic GTase family.
messages: Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.
messages: Nucleus
messages: Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate.

284591:YALI0 E22374g
gene id: 284591:YALI0_E22374g
uniprot id: Q6C4Z7
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 C22616g
gene id: 284591:YALI0_C22616g
uniprot id: F2Z697
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284591:YALI0 A19184g
gene id: 284591:YALI0_A19184g
uniprot id: Q6CGH8
names: Similarity
messages: Belongs to the PIH1 family.

284591:YALI0 C07018g
gene id: 284591:YALI0_C07018g
uniprot id: Q6CCS1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

284591:YALI0 E20603g
gene id: 284591:YALI0_E20603g
uniprot id: Q6C568
names: Similarity
messages: Belongs to the glutaminase PdxT/SNO family.

284591:YALI0 D16863g
gene id: 284591:YALI0_D16863g
uniprot id: Q6C8U8
names: Similarity
messages: Belongs to the protein kinase superfamily.

284591:YALI0 B04642g
gene id: 284591:YALI0_B04642g
uniprot id: Q6CFQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284591:YALI0 E08844g
gene id: 284591:YALI0_E08844g
uniprot id: Q6C6K5
names: Similarity
messages: Belongs to the peptidase C19 family.

284591:YALI0 D08712g
gene id: 284591:YALI0_D08712g
uniprot id: Q6C9S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

284591:YALI0 D12452g
gene id: 284591:YALI0_D12452g
uniprot id: Q6C9B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

284591:YALI0 B22968g
gene id: 284591:YALI0_B22968g
uniprot id: Q6CDL7
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

284591:YALI0 C00495g
gene id: 284591:YALI0_C00495g
uniprot id: Q6CDH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

284591:YALI0 F06336g
gene id: 284591:YALI0_F06336g
uniprot id: Q6C2N8
names: Similarity
messages: Belongs to the peptidase M20A family.

284591:YALI0 E00572g
gene id: 284591:YALI0_E00572g
uniprot id: Q6C7I5
names: Similarity
messages: Belongs to the BolA/IbaG family.

284591:YALI0 F09790g
gene id: 284591:YALI0_F09790g
uniprot id: Q6C290
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

284591:YALI0 E31625g
gene id: 284591:YALI0_E31625g
uniprot id: Q6C3W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: nucleolus

284591:YALI0 E18964g
gene id: 284591:YALI0_E18964g
uniprot id: Q6C5D5
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

284591:YALI0 D05621g
gene id: 284591:YALI0_D05621g
uniprot id: Q6CA61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

284591:YALI0 B01452g
gene id: 284591:YALI0_B01452g
uniprot id: Q6CG25
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 F06791g
gene id: 284591:YALI0_F06791g
uniprot id: Q6C2L6
names: Function
names: Similarity
messages: Belongs to the VPS13 family.
messages: Mediates the transfer of lipids between membranes at organelle contact sites. May play a role in mitochondrial lipid homeostasis.

284591:YALI0 B02750g
gene id: 284591:YALI0_B02750g
uniprot id: Q6CFX6
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

284591:YALI0 A16489g
gene id: 284591:YALI0_A16489g
uniprot id: Q6CGT0
names: Function
names: Similarity
messages: Belongs to the queuosine salvage protein family.
messages: Involved in salvaging queuosine.

284591:YALI0 E11355g
gene id: 284591:YALI0_E11355g
uniprot id: W0TYM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

284591:YALI0 B12804g
gene id: 284591:YALI0_B12804g
uniprot id: Q6CEU7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

284591:YALI0 D24145g
gene id: 284591:YALI0_D24145g
uniprot id: Q6C7Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride exporter Fluc/FEX family.
messages: Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
messages: Membrane

284591:YALI0 B23122g
gene id: 284591:YALI0_B23122g
uniprot id: Q6CDL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Cytoplasm
messages: Mitochondrion

284591:YALI0 D00561g
gene id: 284591:YALI0_D00561g
uniprot id: Q6CAR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the crooked-neck family.
messages: Involved in pre-mRNA splicing and cell cycle progression.
messages: Nucleus

284591:YALI0 E29953g
gene id: 284591:YALI0_E29953g
uniprot id: Q6C439
names: Similarity
messages: Belongs to the PIGH family.

284591:YALI0 E16687g
gene id: 284591:YALI0_E16687g
uniprot id: Q6C5M9
names: Similarity
messages: Belongs to the CCDC25 family.

284591:YALI0 E02508g
gene id: 284591:YALI0_E02508g
uniprot id: Q6C7A1
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 A00132g
gene id: 284591:YALI0_A00132g
uniprot id: Q6CIA7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

284591:YALI0 C00407g
gene id: 284591:YALI0_C00407g
uniprot id: P18120
names: Cofactor
names: Function
names: Sequence Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Defective LEU2 (leu2-270) in genome strain CLIB 122 / E 150 lacks the central section (positions 43 to 269).
messages: Homodimer.

284591:YALI0 F30525g
gene id: 284591:YALI0_F30525g
uniprot id: Q6BZV8
names: Similarity
messages: Belongs to the DNA polymerase type-B-like family.

284591:YALI0 C04213g
gene id: 284591:YALI0_C04213g
uniprot id: Q6CD31
names: Similarity
messages: Belongs to the bystin family.

284591:YALI0 E01782g
gene id: 284591:YALI0_E01782g
uniprot id: Q6C7D2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
messages: Associates in the nucleolus with the 60S and pre-60S ribosomal subunits.
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284591:YALI0 F13057g
gene id: 284591:YALI0_F13057g
uniprot id: Q6C1V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC25 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284591:YALI0 F00176g
gene id: 284591:YALI0_F00176g
uniprot id: Q6C3F5
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B14839g
gene id: 284591:YALI0_B14839g
uniprot id: Q6CEL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion

284591:YALI0 D12727g
gene id: 284591:YALI0_D12727g
uniprot id: Q6C9A4
names: Similarity
messages: Belongs to the eIF2D family.

284591:YALI0 D01177g
gene id: 284591:YALI0_D01177g
uniprot id: Q6CAN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

284591:YALI0 E05995g
gene id: 284591:YALI0_E05995g
uniprot id: Q6C6V2
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

284591:YALI0 C07128g
gene id: 284591:YALI0_C07128g
uniprot id: Q6CCR8
names: Function
names: Similarity
messages: Belongs to the HisA/HisF family.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain.
messages: In the C-terminal section; belongs to the HisA/HisF family.

284591:YALI0 B20878g
gene id: 284591:YALI0_B20878g
uniprot id: Q6CDV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Golgi apparatus membrane
messages: Probable serine protease.
messages: cis-Golgi network membrane

284591:YALI0 D10234g
gene id: 284591:YALI0_D10234g
uniprot id: Q6C9L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha.

284591:YALI0 E01034g
gene id: 284591:YALI0_E01034g
uniprot id: Q6C7G4
names: Similarity
messages: Belongs to the glycosyltransferase 34 family.

284591:YALI0 C02475g
gene id: 284591:YALI0_C02475g
uniprot id: Q6CDA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation.
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 F04664g
gene id: 284591:YALI0_F04664g
uniprot id: Q6C2W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

284591:YALI0 D10274g
gene id: 284591:YALI0_D10274g
uniprot id: B5FVE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

284591:YALI0 E19657g
gene id: 284591:YALI0_E19657g
uniprot id: Q6C5A6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

284591:YALI0 E33847g
gene id: 284591:YALI0_E33847g
uniprot id: Q6C3L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLT11 family.
messages: Involved in pre-mRNA splicing. Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome. Binds to RNA (By similarity).
messages: Nucleus

284591:YALI0 C00231g
gene id: 284591:YALI0_C00231g
uniprot id: Q6CDI6
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

284591:YALI0 E30217g
gene id: 284591:YALI0_E30217g
uniprot id: Q6C430
names: Subcellular Location Annotation
messages: nucleolus

284591:YALI0 F23243g
gene id: 284591:YALI0_F23243g
uniprot id: Q6C0N2
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Homotetramer.

284591:YALI0 C20735g
gene id: 284591:YALI0_C20735g
uniprot id: Q6CBA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
messages: Heterodimer of an alpha and a beta subunit.
messages: Nucleus
messages: cytoskeleton

284591:YALI0 A00638g
gene id: 284591:YALI0_A00638g
uniprot id: Q6CI87
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

284591:YALI0 D13794g
gene id: 284591:YALI0_D13794g
uniprot id: Q6C959
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the small ribosomal subunit.
messages: Cytoplasm
messages: Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability.

284591:YALI0 F23749g
gene id: 284591:YALI0_F23749g
uniprot id: Q6C0L1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

284591:YALI0 C08305g
gene id: 284591:YALI0_C08305g
uniprot id: Q6CCL9
names: Similarity
messages: Belongs to the protein kinase superfamily.

284591:YALI0 D10021g
gene id: 284591:YALI0_D10021g
uniprot id: Q6C9M1
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F26345g
gene id: 284591:YALI0_F26345g
uniprot id: Q6C0A9
names: Similarity
messages: Belongs to the actin family.

284591:YALI0 B21054g
gene id: 284591:YALI0_B21054g
uniprot id: Q6CDU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSA1 family.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

284591:YALI0 E23562g
gene id: 284591:YALI0_E23562g
uniprot id: Q6C4U7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

284591:YALI0 F26455g
gene id: 284591:YALI0_F26455g
uniprot id: Q6C0A4
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

284591:YALI0 C15532g
gene id: 284591:YALI0_C15532g
uniprot id: Q6CBU0
names: Similarity
messages: Belongs to the peptidase S8 family.

284591:YALI0 E01650g
gene id: 284591:YALI0_E01650g
uniprot id: Q6C7D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLD2 family.
messages: Cytoplasm
messages: Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity).
messages: Nucleus

284591:YALI0 B18502g
gene id: 284591:YALI0_B18502g
uniprot id: Q6CE52
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B14751g
gene id: 284591:YALI0_B14751g
uniprot id: Q6CEL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with TAN1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

284591:YALI0 D26730g
gene id: 284591:YALI0_D26730g
uniprot id: Q6C7N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

284591:YALI0 D09801g
gene id: 284591:YALI0_D09801g
uniprot id: Q6C9N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

284591:YALI0 C05346g
gene id: 284591:YALI0_C05346g
uniprot id: Q6CCZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

284591:YALI0 B20768g
gene id: 284591:YALI0_B20768g
uniprot id: Q6CDW1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

284591:YALI0 A16588g
gene id: 284591:YALI0_A16588g
uniprot id: Q6CGS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC2 family.
messages: Nucleus

284591:YALI0 D03267g
gene id: 284591:YALI0_D03267g
uniprot id: Q6CAF4
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

284591:YALI0 F16709g
gene id: 284591:YALI0_F16709g
uniprot id: Q6C1F6
names: Similarity
messages: Belongs to the alkaline phosphatase family.

284591:YALI0 F30173g
gene id: 284591:YALI0_F30173g
uniprot id: Q6BZX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB2 family.
messages: Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

284591:YALI0 E17831g
gene id: 284591:YALI0_E17831g
uniprot id: Q6C5I3
names: Similarity
messages: Belongs to the peptidase M16 family.

284591:YALI0 C06105g
gene id: 284591:YALI0_C06105g
uniprot id: Q6CCV9
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F01606g
gene id: 284591:YALI0_F01606g
uniprot id: Q6C394
names: Function
names: Similarity
messages: Belongs to the dihydroxyacetone kinase (DAK) family.
messages: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.

284591:YALI0 A13585g
gene id: 284591:YALI0_A13585g
uniprot id: Q6CH20
names: Similarity
messages: Belongs to the MNN1/MNT family.

284591:YALI0 F21131g
gene id: 284591:YALI0_F21131g
uniprot id: Q6C0W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX1 family.
messages: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
messages: Forms a heterodimer with SLX4.
messages: Nucleus

284591:YALI0 D13090g
gene id: 284591:YALI0_D13090g
uniprot id: Q6C987
names: Similarity
messages: Belongs to the phosducin family.

284591:YALI0 D04829g
gene id: 284591:YALI0_D04829g
uniprot id: Q6CA93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

284591:YALI0 B16764g
gene id: 284591:YALI0_B16764g
uniprot id: Q6CEC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-H/MCM16 family.
messages: Nucleus
messages: kinetochore

284591:YALI0 E28897g
gene id: 284591:YALI0_E28897g
uniprot id: Q6C485
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: Nucleus

284591:YALI0 F22627g
gene id: 284591:YALI0_F22627g
uniprot id: Q6C0Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

284591:YALI0 D03399g
gene id: 284591:YALI0_D03399g
uniprot id: Q6CAE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

284591:YALI0 E33583g
gene id: 284591:YALI0_E33583g
uniprot id: Q6C3M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

284591:YALI0 D18876g
gene id: 284591:YALI0_D18876g
uniprot id: Q6C8K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 B01914g
gene id: 284591:YALI0_B01914g
uniprot id: Q6CG07
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D09251g
gene id: 284591:YALI0_D09251g
uniprot id: Q6C9Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Component of the nucleolar and nucleoplasmic pre-60S ribosomal particle.
messages: Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

284591:YALI0 B08844g
gene id: 284591:YALI0_B08844g
uniprot id: Q6CFA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

284591:YALI0 B04752g
gene id: 284591:YALI0_B04752g
uniprot id: Q6CFQ6
names: Function
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

284591:YALI0 E32164g
gene id: 284591:YALI0_E32164g
uniprot id: B5FVG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATP synthases have 2 components, the catalytic core F(1) and the membrane-embedded component F(0), linked together by a central stalk and a peripheral stalk (PubMed:27373333). The central stalk, also called rotor shaft, is often seen as part of F(1) (PubMed:27373333). The peripheral stalk is seen as part of F(0) (PubMed:27373333). F(0) contains the membrane channel next to the rotor (PubMed:27373333). F-type ATP synthases form dimers but each monomer functions independently in ATP generation (PubMed:27373333). The dimer consists of 17 different polypeptides: ATP1 (subunit alpha, 3 molecules per monomer, part of F(1)), ATP2 (subunit beta, 3 copies per monomer, part of F(1)), ATP3 (subunit gamma, part of the central stalk), ATP4 (subunit b, part of the peripheral stalk), ATP5/OSCP (subunit 5/OSCP, part of the peripheral stalk), ATP6 (subunit a, part of the peripheral stalk), ATP7 (subunit d, part of the peripheral stalk), ATP8 (subunit 8, part of the peripheral stalk), OLI1 (subunit c, part of the rotor, 10 molecules per monomer), ATP14 (subunit h, part of the peripheral stalk), ATP15 (subunit epsilon, part of the central stalk), ATP16 (subunit delta, part of the central stalk), ATP17 (subunit f, part of the peripheral stalk), ATP18 (subunit i/j, part of the peripheral stalk), ATP19 (subunit k, dimer-specific, at interface between monomers), ATP20 (subunit g, at interface between monomers), TIM11 (subunit e, at interface between monomers) (PubMed:27373333, PubMed:25759169).
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169). F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27373333). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (PubMed:27373333). Part of the complex F(0) domain (PubMed:27373333). Minor subunit located with subunit a/ATP6 in the membrane (PubMed:27373333). Together with subunit g/ATP20, probably contributes to membrane curvature at the site of the ATP synthase dimer, ultimately contributing to formation of cristae (PubMed:27373333).
messages: Mitochondrion inner membrane

284591:YALI0 B23034g
gene id: 284591:YALI0_B23034g
uniprot id: Q6CDL4
names: Similarity
messages: Belongs to the SCC4/mau-2 family.

284591:YALI0 C22792g
gene id: 284591:YALI0_C22792g
uniprot id: Q6CB09
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

284591:YALI0 B13882g
gene id: 284591:YALI0_B13882g
uniprot id: Q6CEQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

284591:YALI0 A15554g
gene id: 284591:YALI0_A15554g
uniprot id: Q6CGW4
names: Similarity
messages: Belongs to the SCC4/mau-2 family.

284591:YALI0 F14575g
gene id: 284591:YALI0_F14575g
uniprot id: Q6C1P3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

284591:YALI0 D26147g
gene id: 284591:YALI0_D26147g
uniprot id: Q6C7R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 C03762g
gene id: 284591:YALI0_C03762g
uniprot id: Q6CD50
names: Function
names: Similarity
messages: Belongs to the LplA family.
messages: Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.

284591:YALI0 F24695g
gene id: 284591:YALI0_F24695g
uniprot id: Q6C0H3
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

284591:YALI0 D25146g
gene id: 284591:YALI0_D25146g
uniprot id: Q6C7V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus

284591:YALI0 A06435g
gene id: 284591:YALI0_A06435g
uniprot id: Q6CHQ5
names: Similarity
messages: Belongs to the peptidase S8 family.

284591:YALI0 F05874g
gene id: 284591:YALI0_F05874g
uniprot id: Q6C2Q9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

284591:YALI0 D15774g
gene id: 284591:YALI0_D15774g
uniprot id: Q6C8Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GcvT family. CAF17 subfamily.
messages: Mitochondrion

284591:YALI0 B03190g
gene id: 284591:YALI0_B03190g
uniprot id: Q6CFW0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284591:YALI0 B01474g
gene id: 284591:YALI0_B01474g
uniprot id: Q6CG24
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 B11418g
gene id: 284591:YALI0_B11418g
uniprot id: Q6CF03
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

284591:YALI0 F17688g
gene id: 284591:YALI0_F17688g
uniprot id: Q6C1B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

284591:YALI0 E22352g
gene id: 284591:YALI0_E22352g
uniprot id: Q6C4Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

284591:YALI0 E24431g
gene id: 284591:YALI0_E24431g
uniprot id: Q6C4R0
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 C04884g
gene id: 284591:YALI0_C04884g
uniprot id: Q6CD07
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B13090g
gene id: 284591:YALI0_B13090g
uniprot id: Q6CET6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D17116g
gene id: 284591:YALI0_D17116g
uniprot id: Q6C8T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

284591:YALI0 B03652g
gene id: 284591:YALI0_B03652g
uniprot id: Q6CFU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROT1 family.
messages: Endoplasmic reticulum membrane
messages: Required for normal levels of the cell wall 1,6-beta-glucan. Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies (By similarity).

284591:YALI0 A13277g
gene id: 284591:YALI0_A13277g
uniprot id: Q6CH28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in cytoplasm to vacuole transport (Cvt) and autophagy by mediating both proteolytic activation and delipidation of ATG8. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. The protease activity is required for proteolytic activation of ATG8: cleaves the C-terminal amino acid of ATG8 to reveal a C-terminal glycine. ATG8 ubiquitin-like activity requires the exposure of the glycine at the C-terminus for its conjugation to phosphatidylethanolamine (PE) and its insertion to membranes, which is necessary for autophagy. The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy. In addition to the protease activity, also catalyzes deconjugation of PE-conjugated forms of ATG8 during macroautophagy: ATG8 delipidation is required to release the protein from membranes, which facilitates multiple events during macroautophagy, and especially for efficient autophagosome biogenesis, the assembly of ATG9-containing tubulovesicular clusters into phagophores/autophagosomes, and for the disassembly of PAS-associated ATG components. ATG8 delipidation by ATG4 also recycles ATG8-PE generated on inappropriate membranes to maintain a reservoir of unlipidated ATG8 that is required for autophagosome formation at the PAS.
messages: Cytoplasm
messages: Nucleus
messages: Preautophagosomal structure

284591:YALI0 D25234g
gene id: 284591:YALI0_D25234g
uniprot id: Q6C7U6
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

284591:YALI0 B10978g
gene id: 284591:YALI0_B10978g
uniprot id: Q6CF21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 A02002g
gene id: 284591:YALI0_A02002g
uniprot id: Q6CI40
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 F30569g
gene id: 284591:YALI0_F30569g
uniprot id: Q6BZV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

284591:YALI0 D08932g
gene id: 284591:YALI0_D08932g
uniprot id: Q6C9R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUR1 family.
messages: Member of a perinuclear network that controls recombination at multiple loci to maintain genome stability. Required for rDNA repeat stability.
messages: Membrane
messages: Nucleus membrane

284591:YALI0 C00451g
gene id: 284591:YALI0_C00451g
uniprot id: Q6CDH6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F01771g
gene id: 284591:YALI0_F01771g
uniprot id: Q6C387
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with cytochrome c oxidase (complex IV, CIV).
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 B06578g
gene id: 284591:YALI0_B06578g
uniprot id: Q6CFI9
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

284591:YALI0 A15576g
gene id: 284591:YALI0_A15576g
uniprot id: Q6CGW3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E07117g
gene id: 284591:YALI0_E07117g
uniprot id: Q6C6Q9
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

284591:YALI0 E15510g
gene id: 284591:YALI0_E15510g
uniprot id: Q6C5S8
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 C18205g
gene id: 284591:YALI0_C18205g
uniprot id: Q6CBJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

284591:YALI0 C18975g
gene id: 284591:YALI0_C18975g
uniprot id: Q6CBG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DUO1 family.
messages: Nucleus
messages: kinetochore

284591:YALI0 C12617g
gene id: 284591:YALI0_C12617g
uniprot id: Q6CC43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

284591:YALI0 F20372g
gene id: 284591:YALI0_F20372g
uniprot id: Q6C102
names: Similarity
messages: Belongs to the SAS10 family.

284591:YALI0 F26156g
gene id: 284591:YALI0_F26156g
uniprot id: B5RSM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 E20955g
gene id: 284591:YALI0_E20955g
uniprot id: Q6C552
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

284591:YALI0 C11671g
gene id: 284591:YALI0_C11671g
uniprot id: Q6CC79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NHP6 family.
messages: Chromosome
messages: DNA-binding protein that induces severe bending of DNA. Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex (By similarity).
messages: Nucleus
messages: Weakly associates with the stable SPT16-POB3 heterodimer to form the FACT complex.

284591:YALI0 F31999g
gene id: 284591:YALI0_F31999g
uniprot id: Q6BZP5
names: Activity Regulation
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
messages: Component of the methylcitrate cycle that catalyzes the formation of pyruvate and succinate from 2-methylisocitrate during the metabolism of endogenous propionyl-CoA.
messages: Inhibited in the presence of NADH and NADPH. When Mg(2+) is present, Cu(2+), Hg(2+) and Zn(2+) inhibit the enzyme activity in some extent.
messages: Mitochondrion matrix
messages: Repressed by glucose.

284591:YALI0 A20922g
gene id: 284591:YALI0_A20922g
uniprot id: Q6CGA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity.
messages: Membrane

284591:YALI0 D24629g
gene id: 284591:YALI0_D24629g
uniprot id: Q6C7X2
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

284591:YALI0 D22913g
gene id: 284591:YALI0_D22913g
uniprot id: Q6C843
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E00462g
gene id: 284591:YALI0_E00462g
uniprot id: Q6C7J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

284591:YALI0 B05170g
gene id: 284591:YALI0_B05170g
uniprot id: Q6CFP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S10 family.
messages: Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).
messages: trans-Golgi network membrane

284591:YALI0 D00429g
gene id: 284591:YALI0_D00429g
uniprot id: Q6CAS1
names: Similarity
messages: Belongs to the p23/wos2 family.

284591:YALI0 E21802g
gene id: 284591:YALI0_E21802g
uniprot id: Q6C519
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.
messages: Chromosome
messages: Histone methyltransferase that trimethylates 'Lys-20' of histone H4 to form H4K20me3.
messages: Nucleus

284591:YALI0 B16390g
gene id: 284591:YALI0_B16390g
uniprot id: Q6CEE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family.
messages: Mitochondrion
messages: N-acetylglutamate synthase involved in arginine biosynthesis.

284591:YALI0 D22572g
gene id: 284591:YALI0_D22572g
uniprot id: Q6C855
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

284591:YALI0 B11000g
gene id: 284591:YALI0_B11000g
uniprot id: Q6CF20
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Component of the mitochondrial large ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S) (By similarity).
messages: Mitochondrion

284591:YALI0 B19382g
gene id: 284591:YALI0_B19382g
uniprot id: Q6CE16
names: Similarity
messages: Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.

284591:YALI0 F04125g
gene id: 284591:YALI0_F04125g
uniprot id: Q6C2Y2
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

284591:YALI0 B16060g
gene id: 284591:YALI0_B16060g
uniprot id: Q6CEF5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

284591:YALI0 A10549g
gene id: 284591:YALI0_A10549g
uniprot id: Q6CHB4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

284591:YALI0 E16929g
gene id: 284591:YALI0_E16929g
uniprot id: Q6C5L8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

284591:YALI0 C08811g
gene id: 284591:YALI0_C08811g
uniprot id: Q6CCJ7
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

284591:YALI0 E27874g
gene id: 284591:YALI0_E27874g
uniprot id: Q6C4C6
names: Similarity
messages: Belongs to the NAD kinase family.

284591:YALI0 C11055g
gene id: 284591:YALI0_C11055g
uniprot id: Q6CCA6
names: Similarity
messages: Belongs to the LSM12 family.

284591:YALI0 F31603g
gene id: 284591:YALI0_F31603g
uniprot id: Q6BZQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Nuclear serine protease which mediates apoptosis.
messages: Nucleus

284591:YALI0 E01936g
gene id: 284591:YALI0_E01936g
uniprot id: Q6C7C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

284591:YALI0 E01738g
gene id: 284591:YALI0_E01738g
uniprot id: Q6C7D4
names: Similarity
messages: Belongs to the KTI12 family.

284591:YALI0 D13728g
gene id: 284591:YALI0_D13728g
uniprot id: Q6C962
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

284591:YALI0 E03256g
gene id: 284591:YALI0_E03256g
uniprot id: Q6C771
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

284591:YALI0 D24299g
gene id: 284591:YALI0_D24299g
uniprot id: Q6C7Y7
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

284591:YALI0 F15807g
gene id: 284591:YALI0_F15807g
uniprot id: Q6C1J2
names: Similarity
messages: Belongs to the PRP18 family.

284591:YALI0 C01463g
gene id: 284591:YALI0_C01463g
uniprot id: Q6CDD1
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 C13816g
gene id: 284591:YALI0_C13816g
uniprot id: Q6CC06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP18 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking.

284591:YALI0 D07722g
gene id: 284591:YALI0_D07722g
uniprot id: Q6C9W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

284591:YALI0 A19074g
gene id: 284591:YALI0_A19074g
uniprot id: Q6CGI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

284591:YALI0 F09009g
gene id: 284591:YALI0_F09009g
uniprot id: Q6C2C5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

284591:YALI0 B05148g
gene id: 284591:YALI0_B05148g
uniprot id: W0TYP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

284591:YALI0 F11803g
gene id: 284591:YALI0_F11803g
uniprot id: Q6C209
names: Similarity
messages: Belongs to the peptidase S10 family.

284591:YALI0 C05577g
gene id: 284591:YALI0_C05577g
uniprot id: Q6CCY3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F07359g
gene id: 284591:YALI0_F07359g
uniprot id: Q6C2J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 C12122g
gene id: 284591:YALI0_C12122g
uniprot id: F2Z6I4
names: Similarity
messages: Belongs to the cytochrome P450 family.

284591:YALI0 A08077g
gene id: 284591:YALI0_A08077g
uniprot id: Q6CHJ9
names: Similarity
messages: Belongs to the PPP phosphatase family.

284591:YALI0 C14718g
gene id: 284591:YALI0_C14718g
uniprot id: Q6CBX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.

284591:YALI0 A15708g
gene id: 284591:YALI0_A15708g
uniprot id: Q6CGV8
names: Subcellular Location Annotation
messages: nucleolus

284591:YALI0 E03058g
gene id: 284591:YALI0_E03058g
uniprot id: Q6C780
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 D02024g
gene id: 284591:YALI0_D02024g
uniprot id: Q6CAK4
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 E29579g
gene id: 284591:YALI0_E29579g
uniprot id: Q6C454
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.

284591:YALI0 B07447g
gene id: 284591:YALI0_B07447g
uniprot id: Q6CFF6
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.

284591:YALI0 C12144g
gene id: 284591:YALI0_C12144g
uniprot id: Q6CC63
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

284591:YALI0 D11330g
gene id: 284591:YALI0_D11330g
uniprot id: Q6C9G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: May mediate the reduction of outer membrane cytochrome b5.
messages: Mitochondrion outer membrane

284591:YALI0 E30393g
gene id: 284591:YALI0_E30393g
uniprot id: Q6C423
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM1 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code.
messages: Nucleus
messages: The JmjC domain mediates the demethylation activity.

284591:YALI0 E26807g
gene id: 284591:YALI0_E26807g
uniprot id: Q6C4H3
names: Similarity
messages: Belongs to the RPAP1 family.

284591:YALI0 B14641g
gene id: 284591:YALI0_B14641g
uniprot id: Q6CEL9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

284591:YALI0 E08969g
gene id: 284591:YALI0_E08969g
uniprot id: Q6C6J9
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E20207g
gene id: 284591:YALI0_E20207g
uniprot id: Q6C584
names: Similarity
messages: Belongs to the hexokinase family.

284591:YALI0 D25388g
gene id: 284591:YALI0_D25388g
uniprot id: Q6C7U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a ternary complex with ATG13 and ATG17.
messages: Preautophagosomal structure membrane
messages: Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates. Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9. Catalyzes phosphorylation of ATG4, decreasing the interaction between ATG4 and ATG8 and impairing deconjugation of PE-conjugated forms of ATG8.

284591:YALI0 D05797g
gene id: 284591:YALI0_D05797g
uniprot id: Q6CA53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus

284591:YALI0 A19954g
gene id: 284591:YALI0_A19954g
uniprot id: Q6CGE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster facilitates the reduction of the catalytic iron-sulfur cluster in the DPH1 subunit.
messages: Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.
messages: Cytoplasm
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1 (By similarity). Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit (By similarity).

284591:YALI0 F16852g
gene id: 284591:YALI0_F16852g
uniprot id: Q6C1F2
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E20801g
gene id: 284591:YALI0_E20801g
uniprot id: Q6C559
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E23342g
gene id: 284591:YALI0_E23342g
uniprot id: Q6C4V7
names: Similarity
messages: Belongs to the PIAS family.

284591:YALI0 F27951g
gene id: 284591:YALI0_F27951g
uniprot id: Q6C042
names: Similarity
messages: Belongs to the PDCD5 family.

284591:YALI0 C23386g
gene id: 284591:YALI0_C23386g
uniprot id: Q6CAY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 E33517g
gene id: 284591:YALI0_E33517g
uniprot id: Q6C3M8
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

284591:YALI0 B14531g
gene id: 284591:YALI0_B14531g
uniprot id: Q6CEM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

284591:YALI0 F21197g
gene id: 284591:YALI0_F21197g
uniprot id: Q6C0W4
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

284591:YALI0 D15862g
gene id: 284591:YALI0_D15862g
uniprot id: Q6C8Y3
names: Similarity
messages: Belongs to the TCP11 family.

284591:YALI0 B13970g
gene id: 284591:YALI0_B13970g
uniprot id: Q6CEQ0
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

284591:YALI0 F07315g
gene id: 284591:YALI0_F07315g
uniprot id: Q6C2J7
names: Similarity
messages: Belongs to the HGH1 family.

284591:YALI0 D08646g
gene id: 284591:YALI0_D08646g
uniprot id: Q6C9S9
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 C21824g
gene id: 284591:YALI0_C21824g
uniprot id: Q6CB54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small GTPase superfamily. SAR1 family.
messages: COPII is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex and SAR1.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SAR1 controls the coat assembly in a stepwise manner. Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex. These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated transport vesicles. Conversion to SAR1-GDP triggers coat release and recycles COPII subunits (By similarity).

284591:YALI0 C18623g
gene id: 284591:YALI0_C18623g
uniprot id: Q6CBH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.
messages: coated pit

284591:YALI0 D16357g
gene id: 284591:YALI0_D16357g
uniprot id: P59680
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Heterooctamer of 4 alpha and 4 beta chains.

284591:YALI0 D10307g
gene id: 284591:YALI0_D10307g
uniprot id: Q6C9K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Component of the GSE complex.
messages: GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.

284591:YALI0 A21098g
gene id: 284591:YALI0_A21098g
uniprot id: Q6CG95
names: Similarity
messages: Belongs to the MOG1 family.

284591:YALI0 E16214g
gene id: 284591:YALI0_E16214g
uniprot id: Q6C5Q1
names: Similarity
messages: Belongs to the TACO1 family.

284591:YALI0 D09317g
gene id: 284591:YALI0_D09317g
uniprot id: Q6C9P8
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E09108g
gene id: 284591:YALI0_E09108g
uniprot id: Q6C6J2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

284591:YALI0 B20526g
gene id: 284591:YALI0_B20526g
uniprot id: Q6CDX2
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 D10549g
gene id: 284591:YALI0_D10549g
uniprot id: Q6C9K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

284591:YALI0 F08371g
gene id: 284591:YALI0_F08371g
uniprot id: Q6C2F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NOP14 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity).
messages: nucleolus

284591:YALI0 D00319g
gene id: 284591:YALI0_D00319g
uniprot id: Q6CAS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

284591:YALI0 A17600g
gene id: 284591:YALI0_A17600g
uniprot id: Q6CGP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

284591:YALI0 B07293g
gene id: 284591:YALI0_B07293g
uniprot id: Q6CFG1
names: Function
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.

284591:YALI0 D24607g
gene id: 284591:YALI0_D24607g
uniprot id: Q6C7X3
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284591:YALI0 F06710g
gene id: 284591:YALI0_F06710g
uniprot id: Q6C2M0
names: Subunit
messages: Homodimer.

284591:YALI0 D20086g
gene id: 284591:YALI0_D20086g
uniprot id: Q6C8F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CEF1 family.
messages: Cytoplasm
messages: Involved in pre-mRNA splicing and cell cycle control.
messages: Nucleus

284591:YALI0 D08228g
gene id: 284591:YALI0_D08228g
uniprot id: F2Z694
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer.

284591:YALI0 F06842g
gene id: 284591:YALI0_F06842g
uniprot id: Q6C2L4
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C00715g
gene id: 284591:YALI0_C00715g
uniprot id: Q6CDG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DASH complex DAD4 family.
messages: Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
messages: Nucleus
messages: The DASH complex oligomerizes to form rings that encircle the microtubules.
messages: kinetochore
messages: spindle

284591:YALI0 B19008g
gene id: 284591:YALI0_B19008g
uniprot id: Q6CE30
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D23705g
gene id: 284591:YALI0_D23705g
uniprot id: Q6C811
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

284591:YALI0 E00154g
gene id: 284591:YALI0_E00154g
uniprot id: Q6C7K1
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

284591:YALI0 D02607g
gene id: 284591:YALI0_D02607g
uniprot id: Q6CAI0
names: Similarity
messages: Belongs to the helicase family.

284591:YALI0 A02244g
gene id: 284591:YALI0_A02244g
uniprot id: Q6CI29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

284591:YALI0 A09812g
gene id: 284591:YALI0_A09812g
uniprot id: Q6CHE2
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

284591:YALI0 D08448g
gene id: 284591:YALI0_D08448g
uniprot id: Q6C9T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS35 family.
messages: Involved in mitochondrial genome encoded proteins translation.
messages: Mitochondrion

284591:YALI0 F20350g
gene id: 284591:YALI0_F20350g
uniprot id: Q6C103
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA and the nucleoplasmic transit of the pre-60S ribosomal subunits. Regulates pre-60S association of the critical remodeling factor MDN1.
messages: Nucleus

284591:YALI0 F14069g
gene id: 284591:YALI0_F14069g
uniprot id: Q6C1R6
names: Similarity
messages: Belongs to the PPP phosphatase family.

284591:YALI0 D18942g
gene id: 284591:YALI0_D18942g
uniprot id: Q6C8K3
names: Function
names: Similarity
messages: Belongs to the TVP38/TMEM64 family.
messages: Golgi membrane protein involved in vesicular trafficking and spindle migration.

284591:YALI0 B15598g
gene id: 284591:YALI0_B15598g
uniprot id: Q6CEH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

284591:YALI0 F03344g
gene id: 284591:YALI0_F03344g
uniprot id: Q6C319
names: Similarity
messages: Belongs to the CNOT9 family.

284591:YALI0 E03410g
gene id: 284591:YALI0_E03410g
uniprot id: Q6C764
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERT1/acuK family.
messages: Nucleus
messages: Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes (By similarity).

284591:YALI0 D00407g
gene id: 284591:YALI0_D00407g
uniprot id: Q6CAS2
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F21945g
gene id: 284591:YALI0_F21945g
uniprot id: Q6C0T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

284591:YALI0 E04510g
gene id: 284591:YALI0_E04510g
uniprot id: Q6C718
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

284591:YALI0 F31493g
gene id: 284591:YALI0_F31493g
uniprot id: Q6BZR4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284591:YALI0 B07161g
gene id: 284591:YALI0_B07161g
uniprot id: Q6CFG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EFG1 family.
messages: Involved in rRNA processing.
messages: nucleolus

284591:YALI0 C23298g
gene id: 284591:YALI0_C23298g
uniprot id: Q6CAY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

284591:YALI0 F20482g
gene id: 284591:YALI0_F20482g
uniprot id: Q6C0Z7
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

284591:YALI0 D06776g
gene id: 284591:YALI0_D06776g
uniprot id: Q6CA11
names: Similarity
messages: Belongs to the RNase PH family.

284591:YALI0 E30723g
gene id: 284591:YALI0_E30723g
uniprot id: Q6C410
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

284591:YALI0 D17138g
gene id: 284591:YALI0_D17138g
uniprot id: Q6C8T4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

284591:YALI0 E32542g
gene id: 284591:YALI0_E32542g
uniprot id: Q6C3S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

284591:YALI0 F15389g
gene id: 284591:YALI0_F15389g
uniprot id: Q6C1K7
names: Similarity
messages: Belongs to the actin family.

284591:YALI0 D27302g
gene id: 284591:YALI0_D27302g
uniprot id: Q6C7K6
names: Subcellular Location Annotation
messages: Peroxisome membrane

284591:YALI0 F06754g
gene id: 284591:YALI0_F06754g
uniprot id: Q6C2L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

284591:YALI0 F23023g
gene id: 284591:YALI0_F23023g
uniprot id: Q6C0P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

284591:YALI0 E09603g
gene id: 284591:YALI0_E09603g
uniprot id: Q6C6H1
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.

284591:YALI0 E10637g
gene id: 284591:YALI0_E10637g
uniprot id: Q6C6C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

284591:YALI0 F15719g
gene id: 284591:YALI0_F15719g
uniprot id: Q6C1J6
names: Similarity
messages: Belongs to the DCP1 family.

284591:YALI0 D25190g
gene id: 284591:YALI0_D25190g
uniprot id: Q6C7U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
messages: Interacts with a number of cyclins.
messages: When phosphate concentrations are high it phosphorylates the PHO4 transcription factor thus establishing repression.

284591:YALI0 F03641g
gene id: 284591:YALI0_F03641g
uniprot id: Q6C305
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Nucleus

284591:YALI0 C16203g
gene id: 284591:YALI0_C16203g
uniprot id: Q6CBR7
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 D09647g
gene id: 284591:YALI0_D09647g
uniprot id: Q6C9N8
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 B11242g
gene id: 284591:YALI0_B11242g
uniprot id: Q6CF11
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B20174g
gene id: 284591:YALI0_B20174g
uniprot id: Q6CDY8
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 F05544g
gene id: 284591:YALI0_F05544g
uniprot id: Q6C2S5
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

284591:YALI0 B16280g
gene id: 284591:YALI0_B16280g
uniprot id: Q6CEE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

284591:YALI0 F12529g
gene id: 284591:YALI0_F12529g
uniprot id: Q6C1Y0
names: Similarity
messages: Belongs to the IUNH family.

284591:YALI0 C11880g
gene id: 284591:YALI0_C11880g
uniprot id: Q6CC71
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

284591:YALI0 D20042g
gene id: 284591:YALI0_D20042g
uniprot id: Q6C8F7
names: Similarity
messages: Belongs to the EFR3 family.

284591:YALI0 E02728g
gene id: 284591:YALI0_E02728g
uniprot id: Q6C791
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
messages: Mitochondrion

284591:YALI0 E11495g
gene id: 284591:YALI0_E11495g
uniprot id: Q6C690
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

284591:YALI0 C21582g
gene id: 284591:YALI0_C21582g
uniprot id: Q6CB64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

284591:YALI0 A02068g
gene id: 284591:YALI0_A02068g
uniprot id: Q6CI37
names: Similarity
messages: Belongs to the activator 1 small subunits family.

284591:YALI0 C18315g
gene id: 284591:YALI0_C18315g
uniprot id: Q6CBJ1
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

284591:YALI0 F17644g
gene id: 284591:YALI0_F17644g
uniprot id: Q6C1B7
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

284591:YALI0 E08184g
gene id: 284591:YALI0_E08184g
uniprot id: Q6C6M5
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: As accessory component of the DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication.
messages: Heterotetramer. Consists of four subunits: POL2, DPB2, DPB3 and DPB4 (By similarity).
messages: In eukaryotes there are five DNA polymerases: alpha, beta, gamma, delta, and epsilon which are responsible for different reactions of DNA synthesis.
messages: Nucleus

284591:YALI0 F02673g
gene id: 284591:YALI0_F02673g
uniprot id: Q6C348
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

284591:YALI0 F10659g
gene id: 284591:YALI0_F10659g
uniprot id: Q6C258
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

284591:YALI0 F23507g
gene id: 284591:YALI0_F23507g
uniprot id: Q6C0M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Membrane
messages: Probably involved in transport through the plasma membrane.

284591:YALI0 E28743g
gene id: 284591:YALI0_E28743g
uniprot id: Q6C491
names: Similarity
messages: Belongs to the peptidase S1B family.

284591:YALI0 E26026g
gene id: 284591:YALI0_E26026g
uniprot id: Q6C4K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

284591:YALI0 C11858g
gene id: 284591:YALI0_C11858g
uniprot id: Q6CC72
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E05973g
gene id: 284591:YALI0_E05973g
uniprot id: Q6C6V3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A10395g
gene id: 284591:YALI0_A10395g
uniprot id: F2Z6B9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

284591:YALI0 D23793g
gene id: 284591:YALI0_D23793g
uniprot id: Q6C807
names: Similarity
messages: Belongs to the VPS26 family.

284591:YALI0 F01320g
gene id: 284591:YALI0_F01320g
uniprot id: F2Z6J3
names: Similarity
messages: Belongs to the cytochrome P450 family.

284591:YALI0 B04224g
gene id: 284591:YALI0_B04224g
uniprot id: Q6CFS7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

284591:YALI0 A07084g
gene id: 284591:YALI0_A07084g
uniprot id: Q6CHM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

284591:YALI0 E18260g
gene id: 284591:YALI0_E18260g
uniprot id: Q6C5G5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
messages: Chromosome
messages: Histone methyltransferase that trimethylates histone H3 'Lys-36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression.
messages: Nucleus
messages: The AWS and SET domains are necessary for transcription repression.

284591:YALI0 E33341g
gene id: 284591:YALI0_E33341g
uniprot id: Q6C3N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284591:YALI0 B03322g
gene id: 284591:YALI0_B03322g
uniprot id: Q6CFV6
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 F30129g
gene id: 284591:YALI0_F30129g
uniprot id: Q6BZX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

284591:YALI0 D20130g
gene id: 284591:YALI0_D20130g
uniprot id: Q8WZL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the palA/RIM20 family.
messages: Interacts with RIM101 by binding to its two YPX[LI] motifs.
messages: Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH. May act as a scaffold protein that recruits the calpain-like protease RIM13 via VPS32 to its substrate RIM101 (By similarity).

284591:YALI0 A08063g
gene id: 284591:YALI0_A08063g
uniprot id: Q6CHK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VTS1 family.
messages: Monomer. Binds to RNA.
messages: P-body
messages: RNA-binding protein involved in post-transcriptional regulation through transcript degradation.
messages: cytosol

284591:YALI0 A16379g
gene id: 284591:YALI0_A16379g
uniprot id: Q6CGT5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

284591:YALI0 C21109g
gene id: 284591:YALI0_C21109g
uniprot id: Q6CB87
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

284591:YALI0 B19998g
gene id: 284591:YALI0_B19998g
uniprot id: Q6CDZ4
names: Cofactor
names: Similarity
messages: Belongs to the glutamate synthase family.
messages: Binds 1 [3Fe-4S] cluster.

284591:YALI0 C17237g
gene id: 284591:YALI0_C17237g
uniprot id: Q6CBM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

284591:YALI0 D09933g
gene id: 284591:YALI0_D09933g
uniprot id: Q6C9M5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the alternative oxidase family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.

284591:YALI0 B03718g
gene id: 284591:YALI0_B03718g
uniprot id: Q6CFU4
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

284591:YALI0 C21021g
gene id: 284591:YALI0_C21021g
uniprot id: Q6CB91
names: Similarity
messages: Belongs to the GST superfamily.

284591:YALI0 B08250g
gene id: 284591:YALI0_B08250g
uniprot id: Q6CFC9
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

284591:YALI0 D03888g
gene id: 284591:YALI0_D03888g
uniprot id: Q6CAD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with DNA double-strand breaks.
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: Nucleus
messages: Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability (By similarity).
messages: telomere

284591:YALI0 F03388g
gene id: 284591:YALI0_F03388g
uniprot id: Q6C317
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

284591:YALI0 B20812g
gene id: 284591:YALI0_B20812g
uniprot id: Q6CDV9
names: Similarity
messages: Belongs to the peptidase S10 family.

284591:YALI0 C08877g
gene id: 284591:YALI0_C08877g
uniprot id: Q6CCJ4
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

284591:YALI0 F29678g
gene id: 284591:YALI0_F29678g
uniprot id: B5RSM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

284591:YALI0 D01804g
gene id: 284591:YALI0_D01804g
uniprot id: Q6CAL1
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

284591:YALI0 D24750g
gene id: 284591:YALI0_D24750g
uniprot id: O74936
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acyl-CoA oxidase family.
messages: Heteropentamer composed of five different subunits.
messages: Oxidizes aliphatic acyl-CoA substrates of different chain lengths such as hexanoyl-CoA, decanoyl-CoA and myristoyl-CoA as well as aromatic/heterocyclic ring-substituted chromogenic substrates, such as furylpropionyl-CoA. Of the above substrates, the efficiency of the enzyme, exhibits the following order: decanoyl-CoA > myristoyl-CoA > hexanoyl-CoA > furyl-propionyl-CoA.
messages: Peroxisome

284591:YALI0 A12133g
gene id: 284591:YALI0_A12133g
uniprot id: Q6CH58
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent rRNA helicase required for pre-ribosomal RNA processing. Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
messages: Interacts with the SSU processome.
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284591:YALI0 C03223g
gene id: 284591:YALI0_C03223g
uniprot id: Q6CD72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 E04642g
gene id: 284591:YALI0_E04642g
uniprot id: Q6C712
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).

284591:YALI0 F14377g
gene id: 284591:YALI0_F14377g
uniprot id: Q6C1Q2
names: Similarity
messages: Belongs to the UTP6 family.

284591:YALI0 F03201g
gene id: 284591:YALI0_F03201g
uniprot id: Q6C325
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 D01573g
gene id: 284591:YALI0_D01573g
uniprot id: Q6CAM0
names: Similarity
messages: Belongs to the EFG1/PHD1/stuA family.

284591:YALI0 E04136g
gene id: 284591:YALI0_E04136g
uniprot id: Q6C733
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 F13651g
gene id: 284591:YALI0_F13651g
uniprot id: Q6C1T0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C09438g
gene id: 284591:YALI0_C09438g
uniprot id: Q6CCH1
names: Similarity
messages: Belongs to the peptidase C19 family.

284591:YALI0 E05775g
gene id: 284591:YALI0_E05775g
uniprot id: Q6C6W2
names: Similarity
messages: Belongs to the RNase H family.

284591:YALI0 F13453g
gene id: 284591:YALI0_F13453g
uniprot id: Q6C1T8
names: Similarity
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.

284591:YALI0 F04422g
gene id: 284591:YALI0_F04422g
uniprot id: Q6C2X0
names: Similarity
names: Subunit
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer (By similarity).

284591:YALI0 A20724g
gene id: 284591:YALI0_A20724g
uniprot id: Q6CGB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWS1 family.
messages: Nucleus
messages: Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription (By similarity).

284591:YALI0 E27181g
gene id: 284591:YALI0_E27181g
uniprot id: Q6C4F6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

284591:YALI0 B20064g
gene id: 284591:YALI0_B20064g
uniprot id: Q6CDZ1
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D08558g
gene id: 284591:YALI0_D08558g
uniprot id: Q6C9T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly. Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum (By similarity).

284591:YALI0 B07513g
gene id: 284591:YALI0_B07513g
uniprot id: Q6CFF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

284591:YALI0 F05082g
gene id: 284591:YALI0_F05082g
uniprot id: Q6C2U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Nucleus

284591:YALI0 A11143g
gene id: 284591:YALI0_A11143g
uniprot id: Q6CH91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.

284591:YALI0 D07414g
gene id: 284591:YALI0_D07414g
uniprot id: Q6C9Y2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

284591:YALI0 A00528g
gene id: 284591:YALI0_A00528g
uniprot id: Q6CI92
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C22770g
gene id: 284591:YALI0_C22770g
uniprot id: F2Z617
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

284591:YALI0 E12243g
gene id: 284591:YALI0_E12243g
uniprot id: Q6C657
names: Subcellular Location Annotation
messages: Cytoplasm

284591:YALI0 F18788g
gene id: 284591:YALI0_F18788g
uniprot id: Q6C168
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MEF2 family.
messages: Nucleus

284591:YALI0 C21802g
gene id: 284591:YALI0_C21802g
uniprot id: Q6CB55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

284591:YALI0 B20702g
gene id: 284591:YALI0_B20702g
uniprot id: Q6CDW4
names: Similarity
messages: Belongs to the cytochrome P450 family.

284591:YALI0 B10021g
gene id: 284591:YALI0_B10021g
uniprot id: Q6CF61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 E18029g
gene id: 284591:YALI0_E18029g
uniprot id: Q6C5H4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.
messages: The active site is a redox-active disulfide bond.

284591:YALI0 F30767g
gene id: 284591:YALI0_F30767g
uniprot id: Q6BZU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.

284591:YALI0 D13046g
gene id: 284591:YALI0_D13046g
uniprot id: Q6C989
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.

284591:YALI0 D21670g
gene id: 284591:YALI0_D21670g
uniprot id: Q6C890
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autopalmitoylated.
messages: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
messages: Endoplasmic reticulum membrane
messages: Interacts with ERF4.
messages: The DHHC domain is required for palmitoyltransferase activity.
messages: The ERF2-ERF4 complex is a palmitoyltransferase specific for Ras proteins.

284591:YALI0 D10065g
gene id: 284591:YALI0_D10065g
uniprot id: Q6C9L9
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

284591:YALI0 F06776g
gene id: 284591:YALI0_F06776g
uniprot id: Q6C2L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 F13805g
gene id: 284591:YALI0_F13805g
uniprot id: Q6C1S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Nucleus
messages: spindle

284591:YALI0 E25982g
gene id: 284591:YALI0_E25982g
uniprot id: Q6C4K6
names: Similarity
messages: Belongs to the cytochrome P450 family.

284591:YALI0 D22520g
gene id: 284591:YALI0_D22520g
uniprot id: Q6C857
names: Similarity
messages: Belongs to the BLM10 family.

284591:YALI0 A15488g
gene id: 284591:YALI0_A15488g
uniprot id: F2Z6A4
names: Similarity
messages: Belongs to the cytochrome P450 family.

284591:YALI0 B20911g
gene id: 284591:YALI0_B20911g
uniprot id: B5FVB7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284591:YALI0 D23353g
gene id: 284591:YALI0_D23353g
uniprot id: Q6C825
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
messages: Membrane

284591:YALI0 F28413g
gene id: 284591:YALI0_F28413g
uniprot id: Q6C023
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

284591:YALI0 C08283g
gene id: 284591:YALI0_C08283g
uniprot id: Q6CCM0
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 D18359g
gene id: 284591:YALI0_D18359g
uniprot id: Q6C8N0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F03025g
gene id: 284591:YALI0_F03025g
uniprot id: Q6C332
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

284591:YALI0 A19470g
gene id: 284591:YALI0_A19470g
uniprot id: Q6CGG9
names: Similarity
messages: Belongs to the WD repeat coronin family.

284591:YALI0 E23947g
gene id: 284591:YALI0_E23947g
uniprot id: Q6C4T2
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

284591:YALI0 F17600g
gene id: 284591:YALI0_F17600g
uniprot id: Q6C1B9
names: Subcellular Location Annotation
messages: Mitochondrion

284591:YALI0 E24321g
gene id: 284591:YALI0_E24321g
uniprot id: Q6C4R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SPCS3 family.
messages: Component of the signal peptidase complex (SPC) composed of a catalytic subunit SEC11 and three accessory subunits SPC1, SPC2 and SPC3 (By similarity). The complex induces a local thinning of the ER membrane which is used to measure the length of the signal peptide (SP) h-region of protein substrates. This ensures the selectivity of the complex towards h-regions shorter than 18-20 amino acids (By similarity). SPC associates with the translocon complex (By similarity).
messages: Endoplasmic reticulum membrane
messages: Essential component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Essential for the SPC catalytic activity, possibly by stabilizing and positioning the active center of the complex close to the lumenal surface. Essential for viability.

284591:YALI0 C18491g
gene id: 284591:YALI0_C18491g
uniprot id: Q6CBI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284591:YALI0 A09042g
gene id: 284591:YALI0_A09042g
uniprot id: F2Z6J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Mitochondrion inner membrane

284591:YALI0 E25718g
gene id: 284591:YALI0_E25718g
uniprot id: Q6C4L8
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 B12826g
gene id: 284591:YALI0_B12826g
uniprot id: Q6CEU6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

284591:YALI0 D26235g
gene id: 284591:YALI0_D26235g
uniprot id: Q6C7Q6
names: Disruption Phenotype
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Defects in hyphal formation.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose (By similarity).

284591:YALI0 F08151g
gene id: 284591:YALI0_F08151g
uniprot id: Q6C2G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 C01023g
gene id: 284591:YALI0_C01023g
uniprot id: F2Z5X4
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

284591:YALI0 F08415g
gene id: 284591:YALI0_F08415g
uniprot id: Q6C2F2
names: Similarity
messages: Belongs to the group II decarboxylase family.

284591:YALI0 C09757g
gene id: 284591:YALI0_C09757g
uniprot id: Q6CCF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

284591:YALI0 B10340g
gene id: 284591:YALI0_B10340g
uniprot id: Q6CF46
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

284591:YALI0 F20108g
gene id: 284591:YALI0_F20108g
uniprot id: Q6C114
names: Similarity
messages: Belongs to the UPP synthase family.

284591:YALI0 E27071g
gene id: 284591:YALI0_E27071g
uniprot id: Q6C4G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTP family.
messages: Involved in protein synthesis. Involved in microtubule stabilization (By similarity).
messages: cytoskeleton

284591:YALI0 A02431g
gene id: 284591:YALI0_A02431g
uniprot id: Q6CI20
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

284591:YALI0 B06556g
gene id: 284591:YALI0_B06556g
uniprot id: Q6CFJ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIS1 family.
messages: Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation (By similarity).
messages: Mitochondrion outer membrane
messages: The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.

284591:YALI0 F19866g
gene id: 284591:YALI0_F19866g
uniprot id: Q6C122
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

284591:YALI0 F24013g
gene id: 284591:YALI0_F24013g
uniprot id: Q6C0K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP14 family.
messages: Cytoplasm

284591:YALI0 B21032g
gene id: 284591:YALI0_B21032g
uniprot id: Q6CDU9
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E13233g
gene id: 284591:YALI0_E13233g
uniprot id: Q6C619
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPL4 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity).
messages: Nucleus membrane
messages: perinuclear region

284591:YALI0 A20570g
gene id: 284591:YALI0_A20570g
uniprot id: Q6CGB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride exporter Fluc/FEX family.
messages: Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
messages: Membrane

284591:YALI0 E15224g
gene id: 284591:YALI0_E15224g
uniprot id: Q6C5T9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane

284591:YALI0 F20922g
gene id: 284591:YALI0_F20922g
uniprot id: Q6C0X7
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D11440g
gene id: 284591:YALI0_D11440g
uniprot id: Q6C9G3
names: Similarity
messages: Belongs to the CWC16 family.

284591:YALI0 F06259g
gene id: 284591:YALI0_F06259g
uniprot id: B5RSL0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B07073g
gene id: 284591:YALI0_B07073g
uniprot id: Q6CFG8
names: Similarity
messages: Belongs to the ATG101 family.

284591:YALI0 F05500g
gene id: 284591:YALI0_F05500g
uniprot id: Q6C2S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 A19052g
gene id: 284591:YALI0_A19052g
uniprot id: Q6CGI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

284591:YALI0 F10098g
gene id: 284591:YALI0_F10098g
uniprot id: Q6C278
names: Similarity
messages: Belongs to the exportin family.

284591:YALI0 F31735g
gene id: 284591:YALI0_F31735g
uniprot id: Q6BZQ3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

284591:YALI0 D11968g
gene id: 284591:YALI0_D11968g
uniprot id: Q6C9D9
names: Similarity
messages: Belongs to the beclin family.

284591:YALI0 B14377g
gene id: 284591:YALI0_B14377g
uniprot id: F2Z6F8
names: Similarity
messages: Belongs to the 14-3-3 family.

284591:YALI0 F00198g
gene id: 284591:YALI0_F00198g
uniprot id: Q6C3F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 3 (AP-3) is a heterotetramer.
messages: Belongs to the adaptor complexes large subunit family.
messages: Golgi apparatus
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.

284591:YALI0 C18689g
gene id: 284591:YALI0_C18689g
uniprot id: P36966
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling. Specifically recognizes PEX5 monoubiquitinated at 'Cys-6', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel. Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5.
messages: Interacts with PEX1; forming the PEX1-PEX6 AAA ATPase complex, which is composed of a heterohexamer formed by a trimer of PEX1-PEX6 dimers.
messages: Peroxisome membrane
messages: cytosol

284591:YALI0 E02002g
gene id: 284591:YALI0_E02002g
uniprot id: Q6C7C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion inner membrane
messages: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.

284591:YALI0 D26994g
gene id: 284591:YALI0_D26994g
uniprot id: Q6C7M0
names: Similarity
messages: Belongs to the RRN3 family.

284591:YALI0 B15059g
gene id: 284591:YALI0_B15059g
uniprot id: P34229
names: Function
names: Similarity
names: Subunit
messages: Belongs to the fungal fatty acid synthetase subunit beta family.
messages: Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl-[acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase.
messages: [Alpha(6)beta(6)] hexamers of two multifunctional subunits (alpha and beta).

284591:YALI0 A18568g
gene id: 284591:YALI0_A18568g
uniprot id: Q6CGK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the cyclophilin-type PPIase family. CWC27 subfamily.
messages: Cytoplasm
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in pre-mRNA splicing (By similarity).

284591:YALI0 D25718g
gene id: 284591:YALI0_D25718g
uniprot id: Q6C7S6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

284591:YALI0 F23375g
gene id: 284591:YALI0_F23375g
uniprot id: F2Z6C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane

284591:YALI0 E15081g
gene id: 284591:YALI0_E15081g
uniprot id: Q6C5U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

284591:YALI0 E12881g
gene id: 284591:YALI0_E12881g
uniprot id: Q6C633
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

284591:YALI0 D20680g
gene id: 284591:YALI0_D20680g
uniprot id: Q6C8C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

284591:YALI0 D21582g
gene id: 284591:YALI0_D21582g
uniprot id: Q6C894
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D03135g
gene id: 284591:YALI0_D03135g
uniprot id: Q6CAF8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Mitochondrion

284591:YALI0 F11759g
gene id: 284591:YALI0_F11759g
uniprot id: Q6C211
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

284591:YALI0 F26191g
gene id: 284591:YALI0_F26191g
uniprot id: Q6C0B4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

284591:YALI0 C21538g
gene id: 284591:YALI0_C21538g
uniprot id: Q6CB66
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C03047g
gene id: 284591:YALI0_C03047g
uniprot id: Q6CD78
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E03784g
gene id: 284591:YALI0_E03784g
uniprot id: Q6C749
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM24 family.
messages: Mitochondrion

284591:YALI0 C18711g
gene id: 284591:YALI0_C18711g
uniprot id: Q6CBH5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 D20262g
gene id: 284591:YALI0_D20262g
uniprot id: Q6C8E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Membrane

284591:YALI0 E22957g
gene id: 284591:YALI0_E22957g
uniprot id: Q6C4X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Endoplasmic reticulum membrane
messages: May be involved in specific transport of UDP-Gal from the cytosol to the Golgi lumen. Involved in the maintenance of optimal conditions for the folding of secretory pathway proteins in the endoplasmic reticulum (By similarity).

284591:YALI0 E33407g
gene id: 284591:YALI0_E33407g
uniprot id: Q6C3N3
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

284591:YALI0 B06941g
gene id: 284591:YALI0_B06941g
uniprot id: Q6CFH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Cytoplasm

284591:YALI0 E24211g
gene id: 284591:YALI0_E24211g
uniprot id: Q6C4S0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C06798g
gene id: 284591:YALI0_C06798g
uniprot id: Q6CCT1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

284591:YALI0 E17963g
gene id: 284591:YALI0_E17963g
uniprot id: Q6C5H7
names: Similarity
messages: Belongs to the NAD kinase family.

284591:YALI0 F09812g
gene id: 284591:YALI0_F09812g
uniprot id: Q6C289
names: Similarity
messages: Belongs to the DeSI family.

284591:YALI0 F06204g
gene id: 284591:YALI0_F06204g
uniprot id: Q6C2P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Nucleus

284591:YALI0 E21692g
gene id: 284591:YALI0_E21692g
uniprot id: Q6C522
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

284591:YALI0 D12012g
gene id: 284591:YALI0_D12012g
uniprot id: Q6C9D7
names: Similarity
messages: Belongs to the NOC2 family.

284591:YALI0 F11517g
gene id: 284591:YALI0_F11517g
uniprot id: Q6C222
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 E32373g
gene id: 284591:YALI0_E32373g
uniprot id: Q6C3T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284591:YALI0 E00220g
gene id: 284591:YALI0_E00220g
uniprot id: Q6C7J8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

284591:YALI0 C18469g
gene id: 284591:YALI0_C18469g
uniprot id: Q6CBI4
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

284591:YALI0 D03718g
gene id: 284591:YALI0_D03718g
uniprot id: Q6CAD6
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

284591:YALI0 F19184g
gene id: 284591:YALI0_F19184g
uniprot id: Q6C152
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 E31218g
gene id: 284591:YALI0_E31218g
uniprot id: Q6C3Y7
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

284591:YALI0 F13519g
gene id: 284591:YALI0_F13519g
uniprot id: Q6C1T5
names: Subcellular Location Annotation
messages: nuclear pore complex

284591:YALI0 B11924g
gene id: 284591:YALI0_B11924g
uniprot id: Q6CEY2
names: Similarity
messages: Belongs to the SIN1 family.

284591:YALI0 E22044g
gene id: 284591:YALI0_E22044g
uniprot id: Q6C508
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

284591:YALI0 C04026g
gene id: 284591:YALI0_C04026g
uniprot id: Q6CD40
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

284591:YALI0 B13508g
gene id: 284591:YALI0_B13508g
uniprot id: Q6CER9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Component of centromeric nucleosomes, where DNA is wrapped around a histone octamer core. The octamer contains two molecules each of H2A, H2B, CSE4/CENPA and H4 assembled in one CSE4-H4 heterotetramer and two H2A-H2B heterodimers. Interacts with the inner kinetochore.
messages: Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes. Replaces conventional H3 in the nucleosome core of centromeric chromatin that serves as an assembly site for the inner kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division (By similarity).
messages: Nucleus
messages: Ubiquitinated. Is degraded through ubiquitin-mediated proteolysis when not protected by its association to the kinetochore.
messages: centromere

284591:YALI0 E29249g
gene id: 284591:YALI0_E29249g
uniprot id: Q6C470
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

284591:YALI0 F14135g
gene id: 284591:YALI0_F14135g
uniprot id: Q6C1R3
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

284591:YALI0 D15092g
gene id: 284591:YALI0_D15092g
uniprot id: Q6C917
names: Similarity
messages: Belongs to the yippee family.

284591:YALI0 A08646g
gene id: 284591:YALI0_A08646g
uniprot id: Q6CHH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC12 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Guanine nucleotide-exchange factor (GEF) required for the formation or budding of transport vesicles from the ER.

284591:YALI0 F30481g
gene id: 284591:YALI0_F30481g
uniprot id: Q6BZW0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

284591:YALI0 D05819g
gene id: 284591:YALI0_D05819g
uniprot id: Q6CA52
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A13519g
gene id: 284591:YALI0_A13519g
uniprot id: Q6CH23
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

284591:YALI0 B01848g
gene id: 284591:YALI0_B01848g
uniprot id: F2Z623
names: Similarity
messages: Belongs to the cytochrome P450 family.

284591:YALI0 B01606g
gene id: 284591:YALI0_B01606g
uniprot id: Q6CG20
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. SWF1 subfamily.
messages: Endoplasmic reticulum membrane
messages: Palmitoyltransferase that targets several endosomal SNAREs. Palmitoylates the SNAREs at cysteine residues close to the cytoplasmic end of their transmembrane domain. May have a role in the cellular quality control of transmembrane domain-containing proteins (By similarity).
messages: The DHHC domain is required for palmitoyltransferase activity.

284591:YALI0 D04268g
gene id: 284591:YALI0_D04268g
uniprot id: Q6CAB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Forms a one-to-one complex with cytochrome c.
messages: Mitochondrion matrix

284591:YALI0 D18612g
gene id: 284591:YALI0_D18612g
uniprot id: Q6C8L8
names: Function
names: Subcellular Location Annotation
messages: Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 E14685g
gene id: 284591:YALI0_E14685g
uniprot id: O74932
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.
messages: Synthase catalytic subunit of the trehalose synthase complex that catalyzes the production of trehalose from glucose-6-phosphate and UDP-alpha-D-glucose in a two step process (PubMed:21931609). The disaccharide trehalose serves as a storage carbohydrate that is mobilized during spore germination (PubMed:21931609).

284591:YALI0 E15037g
gene id: 284591:YALI0_E15037g
uniprot id: Q6C5U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284591:YALI0 A17946g
gene id: 284591:YALI0_A17946g
uniprot id: B5RSK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFB10 subunit family.
messages: Mitochondrion inner membrane

284591:YALI0 A20295g
gene id: 284591:YALI0_A20295g
uniprot id: Q6CGD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2H phosphoesterase superfamily. CPD1 family.
messages: Golgi apparatus
messages: Involved in the metabolism of ADP-ribose 1',2'-cyclic phosphate which is produced as a consequence of tRNA splicing.

284591:YALI0 D19954g
gene id: 284591:YALI0_D19954g
uniprot id: Q6C8G1
names: Similarity
messages: Belongs to the TMA16 family.

284591:YALI0 F20988g
gene id: 284591:YALI0_F20988g
uniprot id: Q6C0X4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

284591:YALI0 C18799g
gene id: 284591:YALI0_C18799g
uniprot id: Q6CBH1
names: Similarity
messages: Belongs to the UPP synthase family.

284591:YALI0 E16346g
gene id: 284591:YALI0_E16346g
uniprot id: Q6C5P5
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

284591:YALI0 A09086g
gene id: 284591:YALI0_A09086g
uniprot id: Q6CHG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WHI5/NRM1 family.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 B01408g
gene id: 284591:YALI0_B01408g
uniprot id: Q6CG27
names: Similarity
messages: Belongs to the peptidase S10 family.

284591:YALI0 B03014g
gene id: 284591:YALI0_B03014g
uniprot id: Q6CFW5
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 A17171g
gene id: 284591:YALI0_A17171g
uniprot id: Q6CGR0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B12958g
gene id: 284591:YALI0_B12958g
uniprot id: Q6CEU0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM14 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1) (By similarity).
messages: Heterodimer with PAM16. Component of the PAM complex, at least composed of mtHsp70, MGE1, TIM44, PAM16, PAM17 and PAM18 (By similarity).
messages: Mitochondrion inner membrane
messages: The J domain is essential for co-chaperone activity and mediates the heterodimerization with the J-like domain of PAM16.

284591:YALI0 E12507g
gene id: 284591:YALI0_E12507g
uniprot id: Q6C646
names: Similarity
messages: Belongs to the pirin family.

284591:YALI0 C01331g
gene id: 284591:YALI0_C01331g
uniprot id: Q6CDD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

284591:YALI0 B21428g
gene id: 284591:YALI0_B21428g
uniprot id: Q6CDT1
names: Function
messages: Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).

284591:YALI0 D02563g
gene id: 284591:YALI0_D02563g
uniprot id: Q6CAI2
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

284591:YALI0 C10802g
gene id: 284591:YALI0_C10802g
uniprot id: Q6CCB8
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

284591:YALI0 F30426g
gene id: 284591:YALI0_F30426g
uniprot id: B5RSM6
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

284591:YALI0 B13134g
gene id: 284591:YALI0_B13134g
uniprot id: Q6CET4
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E16038g
gene id: 284591:YALI0_E16038g
uniprot id: Q6C5Q7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

284591:YALI0 F14487g
gene id: 284591:YALI0_F14487g
uniprot id: Q6C1P7
names: Similarity
messages: Belongs to the JHDM3 histone demethylase family.

284591:YALI0 E21373g
gene id: 284591:YALI0_E21373g
uniprot id: Q6C535
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

284591:YALI0 D24409g
gene id: 284591:YALI0_D24409g
uniprot id: Q6C7Y2
names: Similarity
messages: Belongs to the PurH family.

284591:YALI0 F11825g
gene id: 284591:YALI0_F11825g
uniprot id: Q6C208
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B16434g
gene id: 284591:YALI0_B16434g
uniprot id: Q6CED9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

284591:YALI0 C07414g
gene id: 284591:YALI0_C07414g
uniprot id: Q6CCQ8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284591:YALI0 B04202g
gene id: 284591:YALI0_B04202g
uniprot id: Q6CFS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

284591:YALI0 B23210g
gene id: 284591:YALI0_B23210g
uniprot id: Q6CDK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: nucleolus

284591:YALI0 B13706g
gene id: 284591:YALI0_B13706g
uniprot id: Q6CER2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Nucleus

284591:YALI0 D05489g
gene id: 284591:YALI0_D05489g
uniprot id: Q6CA67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

284591:YALI0 A10945g
gene id: 284591:YALI0_A10945g
uniprot id: Q6CH98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUF2 family.
messages: kinetochore

284591:YALI0 A17061g
gene id: 284591:YALI0_A17061g
uniprot id: Q6CGR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DASH complex DAD2 family.
messages: Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
messages: Nucleus
messages: The DASH complex oligomerizes to form rings that encircle the microtubules.
messages: kinetochore
messages: spindle

284591:YALI0 D17204g
gene id: 284591:YALI0_D17204g
uniprot id: Q6C8T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

284591:YALI0 B12320g
gene id: 284591:YALI0_B12320g
uniprot id: Q6CEW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. The complex is held together by ERB1, which interacts with NOP7 via its N-terminal domain and with YTM1 via a high-affinity interaction between the seven-bladed beta-propeller domains of the 2 proteins. The NOP7 complex associates with the 66S pre-ribosome. Interacts (via UBL domain) with MDN1 (via VWFA/MIDAS domain).
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

284591:YALI0 C12100g
gene id: 284591:YALI0_C12100g
uniprot id: Q6CC65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

284591:YALI0 C07722g
gene id: 284591:YALI0_C07722g
uniprot id: Q6CCP4
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F20240g
gene id: 284591:YALI0_F20240g
uniprot id: Q6C108
names: Similarity
messages: Belongs to the RNase PH family.

284591:YALI0 E29645g
gene id: 284591:YALI0_E29645g
uniprot id: Q6C451
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E20823g
gene id: 284591:YALI0_E20823g
uniprot id: Q6C558
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 E29506g
gene id: 284591:YALI0_E29506g
uniprot id: Q6C457
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HEATR1/UTP10 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity).
messages: Membrane
messages: nucleolus

284591:YALI0 F01056g
gene id: 284591:YALI0_F01056g
uniprot id: Q6C3B5
names: Similarity
messages: Belongs to the RICTOR family.

284591:YALI0 F02211g
gene id: 284591:YALI0_F02211g
uniprot id: Q6C367
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284591:YALI0 F25421g
gene id: 284591:YALI0_F25421g
uniprot id: Q6C0E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC15 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284591:YALI0 E34353g
gene id: 284591:YALI0_E34353g
uniprot id: Q6C3J3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in mitochondrial RNA metabolism. Required for maintenance of mitochondrial DNA (By similarity).
messages: Belongs to the DEAD box helicase family. MRH4 subfamily.
messages: Mitochondrion
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284591:YALI0 C20757g
gene id: 284591:YALI0_C20757g
uniprot id: Q6CBA1
names: Similarity
messages: Belongs to the patched family.

284591:YALI0 A06589g
gene id: 284591:YALI0_A06589g
uniprot id: Q6CHQ0
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

284591:YALI0 D26928g
gene id: 284591:YALI0_D26928g
uniprot id: Q6C7M3
names: Function
names: Similarity
messages: Belongs to the BLOC1S4 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex that is involved in endosomal cargo sorting.

284591:YALI0 F16643g
gene id: 284591:YALI0_F16643g
uniprot id: Q6C1F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

284591:YALI0 F11473g
gene id: 284591:YALI0_F11473g
uniprot id: Q6C224
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

284591:YALI0 F20306g
gene id: 284591:YALI0_F20306g
uniprot id: Q6C105
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATP synthases have 2 components, the catalytic core F(1) and the membrane-embedded component F(0), linked together by a central stalk and a peripheral stalk (PubMed:27373333). The central stalk, also called rotor shaft, is often seen as part of F(1) (PubMed:27373333). The peripheral stalk is seen as part of F(0) (PubMed:27373333). F(0) contains the membrane channel next to the rotor (PubMed:27373333). F-type ATP synthases form dimers but each monomer functions independently in ATP generation (PubMed:27373333). The dimer consists of 17 different polypeptides: ATP1 (subunit alpha, 3 molecules per monomer, part of F(1)), ATP2 (subunit beta, 3 copies per monomer, part of F(1)), ATP3 (subunit gamma, part of the central stalk), ATP4 (subunit b, part of the peripheral stalk), ATP5/OSCP (subunit 5/OSCP, part of the peripheral stalk), ATP6 (subunit a, part of the peripheral stalk), ATP7 (subunit d, part of the peripheral stalk), ATP8 (subunit 8, part of the peripheral stalk), OLI1 (subunit c, part of the rotor, 10 molecules per monomer), ATP14 (subunit h, part of the peripheral stalk), ATP15 (subunit epsilon, part of the central stalk), ATP16 (subunit delta, part of the central stalk), ATP17 (subunit f, part of the peripheral stalk), ATP18 (subunit i/j, part of the peripheral stalk), ATP19 (subunit k, dimer-specific, at interface between monomers), ATP20 (subunit g, at interface between monomers), TIM11 (subunit e, at interface between monomers) (PubMed:27373333, PubMed:25759169).
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169). F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27373333). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (PubMed:27373333). Part of the complex F(0) domain and the peripheral stalk, which acts as a stator to hold the catalytic alpha/ATP1(3)beta/ATP2(3) subcomplex and subunit a/ATP6 static relative to the rotary elements (PubMed:27373333).
messages: Mitochondrion inner membrane

284591:YALI0 E20383g
gene id: 284591:YALI0_E20383g
uniprot id: Q6C578
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYSTM1 family.
messages: Membrane

284591:YALI0 D21934g
gene id: 284591:YALI0_D21934g
uniprot id: Q6C881
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

284591:YALI0 B18348g
gene id: 284591:YALI0_B18348g
uniprot id: Q6CE59
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

284591:YALI0 F31977g
gene id: 284591:YALI0_F31977g
uniprot id: Q6BZP6
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

284591:YALI0 D03960g
gene id: 284591:YALI0_D03960g
uniprot id: Q6CAC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP25 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.
messages: DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
messages: nucleolus

284591:YALI0 F24981g
gene id: 284591:YALI0_F24981g
uniprot id: Q6C0G3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPH3 family.
messages: Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.
messages: Cytoplasm
messages: Nucleus
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising KTI11/DPH3 and a NADH-dependent reductase, predominantly CBR1. Acts as an electron donor to reduce the Fe-S cluster in DPH1-DPH2 keeping the [4Fe-4S] clusters in the active and reduced state. Restores iron to DPH1-DPH2 iron-sulfur clusters which have degraded from [4Fe-4S] to [3Fe-4S] by donating an iron atom to reform [4Fe-4S] clusters, in a manner dependent on the presence of elongation factor 2 and SAM. Associates with the elongator complex and is required for tRNA Wobble base modifications mediated by the elongator complex. The elongator complex is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine).
messages: The DPH-type metal-binding (MB) domain can also bind zinc. However, iron is the physiological binding partner as zinc binding impairs the protein electron donor function.

284591:YALI0 A03443g
gene id: 284591:YALI0_A03443g
uniprot id: Q6CHY6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasm
messages: Membrane
messages: Required for vacuolar protein sorting.
messages: The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization.

284591:YALI0 B00132g
gene id: 284591:YALI0_B00132g
uniprot id: Q6CG77
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 C16643g
gene id: 284591:YALI0_C16643g
uniprot id: Q6CBQ0
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E05533g
gene id: 284591:YALI0_E05533g
uniprot id: P41929
names: Activity Regulation
names: Function
messages: Activity is inhibited by 5-aminovalerate.
messages: Lysine N-6-acetyl transferase (LAT) that catalyzes the first step of the lysine degradation pathway.

284591:YALI0 E23859g
gene id: 284591:YALI0_E23859g
uniprot id: Q6C4T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

284591:YALI0 D12661g
gene id: 284591:YALI0_D12661g
uniprot id: Q6C9A7
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

284591:YALI0 E11011g
gene id: 284591:YALI0_E11011g
uniprot id: Q6C6A9
names: Function
names: Subcellular Location Annotation
messages: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Membrane
messages: Mitochondrion inner membrane
messages: Nucleus

284591:YALI0 C09735g
gene id: 284591:YALI0_C09735g
uniprot id: Q6CCF9
names: Similarity
messages: Belongs to the RutC family.

284591:YALI0 F10010g
gene id: 284591:YALI0_F10010g
uniprot id: Q6C282
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLPL family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lipid hydrolase.
messages: Membrane

284591:YALI0 B21824g
gene id: 284591:YALI0_B21824g
uniprot id: Q6CDR6
names: Similarity
messages: Belongs to the cytochrome P450 family.

284591:YALI0 C04730g
gene id: 284591:YALI0_C04730g
uniprot id: Q6CD11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 B13310g
gene id: 284591:YALI0_B13310g
uniprot id: Q6CES8
names: Similarity
messages: Belongs to the peptidase M14 family.

284591:YALI0 F06358g
gene id: 284591:YALI0_F06358g
uniprot id: Q6C2N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Binds to both phosphatidylinositol (PI) and phosphatidylinositol 3,5-bisphosphate (PIP2).
messages: Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by ATG15 is critical to life span extension (By similarity).
messages: Prevacuolar compartment membrane
messages: multivesicular body membrane

284591:YALI0 D17072g
gene id: 284591:YALI0_D17072g
uniprot id: Q6C8T8
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

284591:YALI0 F15851g
gene id: 284591:YALI0_F15851g
uniprot id: Q6C1J0
names: Similarity
messages: Belongs to the SGT1 family.

284591:YALI0 A05247g
gene id: 284591:YALI0_A05247g
uniprot id: Q6CHT2
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

284591:YALI0 D10923g
gene id: 284591:YALI0_D10923g
uniprot id: Q6C9I6
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Telomere-binding protein that mediates telomere clustering by promoting formation of head-to-head dimers of DNA molecules through the telomeric tracts. Binds specifically 5'-TTAGTCAGGG-3' repeats in subtelomeric regions.
messages: The presence of both Myb domains is required for high affinity telomeric DNA-binding.
messages: telomere

284591:YALI0 E06545g
gene id: 284591:YALI0_E06545g
uniprot id: Q6C6T1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DPH4 family.
messages: Cytoplasm
messages: Nucleus
messages: Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2 (By similarity).
messages: The DPH-type metal-binding (MB) domain can bind either zinc or iron ions.

284591:YALI0 A12969g
gene id: 284591:YALI0_A12969g
uniprot id: Q6CH38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus

284591:YALI0 D23859g
gene id: 284591:YALI0_D23859g
uniprot id: Q6C804
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of a heterotrimeric complex containing IMP3, IMP4 and MPP10.
messages: Component of the U3 small nucleolar ribonucleoprotein. Required for the early cleavages at sites A0, A1 and A2 during 18S ribosomal pre-RNA processing (By similarity).
messages: nucleolus

284591:YALI0 C17831g
gene id: 284591:YALI0_C17831g
uniprot id: Q6CBL1
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

284591:YALI0 C06127g
gene id: 284591:YALI0_C06127g
uniprot id: Q6CCV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284591:YALI0 F06050g
gene id: 284591:YALI0_F06050g
uniprot id: Q6C2Q1
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

284591:YALI0 C12793g
gene id: 284591:YALI0_C12793g
uniprot id: Q6CC37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

284591:YALI0 D02849g
gene id: 284591:YALI0_D02849g
uniprot id: Q6CAG9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
messages: Component of the signal peptidase complex (SPC) composed of a catalytic subunit SEC11 and three accessory subunits SPC1, SPC2 and SPC3 (By similarity). The complex induces a local thinning of the ER membrane which is used to measure the length of the signal peptide (SP) h-region of protein substrates. This ensures the selectivity of the complex towards h-regions shorter than 18-20 amino acids (By similarity). SPC associates with the translocon complex (By similarity).
messages: Endoplasmic reticulum membrane
messages: The C-terminal short (CTS) helix is essential for catalytic activity. It may be accommodated as a transmembrane helix in the thinned membrane environment of the complex, similarly to the signal peptide in the complex substrates.

284591:YALI0 F02431g
gene id: 284591:YALI0_F02431g
uniprot id: Q6C357
names: Similarity
messages: Belongs to the RAD52 family.

284591:YALI0 B15015g
gene id: 284591:YALI0_B15015g
uniprot id: Q6CEK2
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E34826g
gene id: 284591:YALI0_E34826g
uniprot id: B5FVG8
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

284591:YALI0 A20482g
gene id: 284591:YALI0_A20482g
uniprot id: Q6CGC4
names: Function
messages: Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

284591:YALI0 F17820g
gene id: 284591:YALI0_F17820g
uniprot id: Q6C1A9
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

284591:YALI0 C11946g
gene id: 284591:YALI0_C11946g
uniprot id: Q6CC70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO70 family.
messages: Bud
messages: Bud neck
messages: Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst (By similarity).

284591:YALI0 B14487g
gene id: 284591:YALI0_B14487g
uniprot id: Q6CEM6
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

284591:YALI0 F18359g
gene id: 284591:YALI0_F18359g
uniprot id: B5RSL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 C18557g
gene id: 284591:YALI0_C18557g
uniprot id: Q6CBI0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

284591:YALI0 C13090g
gene id: 284591:YALI0_C13090g
uniprot id: Q6CC28
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

284591:YALI0 B00704g
gene id: 284591:YALI0_B00704g
uniprot id: Q6CG57
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.
messages: cytosol

284591:YALI0 E21868g
gene id: 284591:YALI0_E21868g
uniprot id: Q6C516
names: Similarity
messages: Belongs to the AAA ATPase family.

284591:YALI0 D00891g
gene id: 284591:YALI0_D00891g
uniprot id: P87200
names: Function
names: Subcellular Location Annotation
messages: Involved in peroxisome biosynthesis. Required for the import of a subset of matrix proteins into peroxisomes.
messages: Peroxisome membrane

284591:YALI0 C05280g
gene id: 284591:YALI0_C05280g
uniprot id: Q6CCZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 A01353g
gene id: 284591:YALI0_A01353g
uniprot id: Q6CI63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

284591:YALI0 B04840g
gene id: 284591:YALI0_B04840g
uniprot id: Q6CFQ4
names: Similarity
messages: Belongs to the protein kinase superfamily.

284591:YALI0 F04059g
gene id: 284591:YALI0_F04059g
uniprot id: Q6C2Y6
names: Function
names: Similarity
messages: Belongs to the peptidase C14B family.
messages: Involved in cell death (apoptosis).

284591:YALI0 E19987g
gene id: 284591:YALI0_E19987g
uniprot id: Q6C594
names: Similarity
messages: Belongs to the VPS29 family.

284591:YALI0 C04796g
gene id: 284591:YALI0_C04796g
uniprot id: Q6CD09
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B22858g
gene id: 284591:YALI0_B22858g
uniprot id: Q6CDM2
names: Similarity
messages: Belongs to the MON2 family.

284591:YALI0 A04917g
gene id: 284591:YALI0_A04917g
uniprot id: Q6CHU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

284591:YALI0 A09383g
gene id: 284591:YALI0_A09383g
uniprot id: F2Z6D9
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E23133g
gene id: 284591:YALI0_E23133g
uniprot id: Q6C4W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

284591:YALI0 E32241g
gene id: 284591:YALI0_E32241g
uniprot id: Q6C3T6
names: Similarity
messages: Belongs to the NSRP1 family.

284591:YALI0 E09691g
gene id: 284591:YALI0_E09691g
uniprot id: Q6C6G7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

284591:YALI0 C24057g
gene id: 284591:YALI0_C24057g
uniprot id: Q6CAV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

284591:YALI0 F21032g
gene id: 284591:YALI0_F21032g
uniprot id: Q6C0X2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity).
messages: Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
messages: P-body
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284591:YALI0 C13706g
gene id: 284591:YALI0_C13706g
uniprot id: Q6CC10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

284591:YALI0 B22440g
gene id: 284591:YALI0_B22440g
uniprot id: Q6CDP1
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

284591:YALI0 D15114g
gene id: 284591:YALI0_D15114g
uniprot id: Q6C916
names: Similarity
messages: Belongs to the FGGY kinase family.

284591:YALI0 E20185g
gene id: 284591:YALI0_E20185g
uniprot id: Q6C585
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

284591:YALI0 B20504g
gene id: 284591:YALI0_B20504g
uniprot id: Q6CDX3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

284591:YALI0 A01870g
gene id: 284591:YALI0_A01870g
uniprot id: Q6CI44
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

284591:YALI0 F10076g
gene id: 284591:YALI0_F10076g
uniprot id: Q6C279
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

284591:YALI0 B13794g
gene id: 284591:YALI0_B13794g
uniprot id: Q6CEQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

284591:YALI0 F22033g
gene id: 284591:YALI0_F22033g
uniprot id: Q6C0S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

284591:YALI0 E10351g
gene id: 284591:YALI0_E10351g
uniprot id: Q6C6D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284591:YALI0 E12441g
gene id: 284591:YALI0_E12441g
uniprot id: Q6C649
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

284591:YALI0 B04400g
gene id: 284591:YALI0_B04400g
uniprot id: Q6CFR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPDU1 (TC 2.A.43.3) family.
messages: Membrane

284591:YALI0 D20196g
gene id: 284591:YALI0_D20196g
uniprot id: Q6C8F0
names: Disruption Phenotype
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Abolishes citrate export.
messages: Belongs to the major facilitator superfamily.
messages: Cell membrane
messages: Transmembrane transporter that exports citrate across the cell membrane.

284591:YALI0 A13057g
gene id: 284591:YALI0_A13057g
uniprot id: Q6CH35
names: Similarity
messages: Belongs to the RNase Z family.

284591:YALI0 D22264g
gene id: 284591:YALI0_D22264g
uniprot id: Q6C868
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.

284591:YALI0 F16203g
gene id: 284591:YALI0_F16203g
uniprot id: Q6C1H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG8 family.
messages: Membrane

284591:YALI0 D09691g
gene id: 284591:YALI0_D09691g
uniprot id: Q6C9N6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

284591:YALI0 D05071g
gene id: 284591:YALI0_D05071g
uniprot id: Q6CA82
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

284591:YALI0 B12694g
gene id: 284591:YALI0_B12694g
uniprot id: Q6CEV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy (By similarity).

284591:YALI0 F10241g
gene id: 284591:YALI0_F10241g
uniprot id: Q6C271
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284591:YALI0 A04521g
gene id: 284591:YALI0_A04521g
uniprot id: Q6CHV6
names: Similarity
messages: Belongs to the RNase H family.

284591:YALI0 F05610g
gene id: 284591:YALI0_F05610g
uniprot id: Q6C2S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

284591:YALI0 F26521g
gene id: 284591:YALI0_F26521g
uniprot id: Q6C0A1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

284591:YALI0 B02860g
gene id: 284591:YALI0_B02860g
uniprot id: Q6CFX0
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S2 family.

284591:YALI0 A03949g
gene id: 284591:YALI0_A03949g
uniprot id: Q6CHW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284591:YALI0 F15829g
gene id: 284591:YALI0_F15829g
uniprot id: Q6C1J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm.
messages: nucleolus

284591:YALI0 F22539g
gene id: 284591:YALI0_F22539g
uniprot id: Q874C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-3 family.
messages: Involved in peroxisome biosynthesis. Seems to directly or indirectly sequesters components of the peroxisome biogenesis machinery.
messages: Peroxisome membrane

284591:YALI0 F02277g
gene id: 284591:YALI0_F02277g
uniprot id: Q6C364
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

284591:YALI0 C08052g
gene id: 284591:YALI0_C08052g
uniprot id: Q6CCN1
names: Similarity
messages: Belongs to the MAK16 family.

284591:YALI0 A18590g
gene id: 284591:YALI0_A18590g
uniprot id: Q6CGK3
names: Similarity
messages: Belongs to the protein kinase superfamily.

284591:YALI0 F06424g
gene id: 284591:YALI0_F06424g
uniprot id: Q6C2N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

284591:YALI0 E31009g
gene id: 284591:YALI0_E31009g
uniprot id: Q6C3Z7
names: Similarity
messages: Belongs to the uridine kinase family.

284591:YALI0 C18425g
gene id: 284591:YALI0_C18425g
uniprot id: Q6CBI6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284591:YALI0 D17490g
gene id: 284591:YALI0_D17490g
uniprot id: Q6C8S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase j subunit family.
messages: F-type ATP synthases have 2 components, the catalytic core F(1) and the membrane-embedded component F(0), linked together by a central stalk and a peripheral stalk (PubMed:27373333). The central stalk, also called rotor shaft, is often seen as part of F(1) (PubMed:27373333). The peripheral stalk is seen as part of F(0) (PubMed:27373333). F(0) contains the membrane channel next to the rotor (PubMed:27373333). F-type ATP synthases form dimers but each monomer functions independently in ATP generation (PubMed:27373333). The dimer consists of 17 different polypeptides: ATP1 (subunit alpha, 3 molecules per monomer, part of F(1)), ATP2 (subunit beta, 3 copies per monomer, part of F(1)), ATP3 (subunit gamma, part of the central stalk), ATP4 (subunit b, part of the peripheral stalk), ATP5/OSCP (subunit 5/OSCP, part of the peripheral stalk), ATP6 (subunit a, part of the peripheral stalk), ATP7 (subunit d, part of the peripheral stalk), ATP8 (subunit 8, part of the peripheral stalk), OLI1 (subunit c, part of the rotor, 10 molecules per monomer), ATP14 (subunit h, part of the peripheral stalk), ATP15 (subunit epsilon, part of the central stalk), ATP16 (subunit delta, part of the central stalk), ATP17 (subunit f, part of the peripheral stalk), ATP18 (subunit i/j, part of the peripheral stalk), ATP19 (subunit k, dimer-specific, at interface between monomers), ATP20 (subunit g, at interface between monomers), TIM11 (subunit e, at interface between monomers) (PubMed:27373333, PubMed:25759169).
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169). F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27373333). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (PubMed:27373333). Part of the complex F(0) domain (PubMed:27373333). Minor subunit located with subunit a/ATP6 in the membrane (PubMed:27373333).
messages: Mitochondrion inner membrane

284591:YALI0 B17842g
gene id: 284591:YALI0_B17842g
uniprot id: Q6CE79
names: Similarity
messages: Belongs to the WD repeat RTC1 family.

284591:YALI0 F23947g
gene id: 284591:YALI0_F23947g
uniprot id: Q6C0K3
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

284591:YALI0 B12276g
gene id: 284591:YALI0_B12276g
uniprot id: Q6CEW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM MRD1 family.
messages: Involved in pre-rRNA processing.
messages: Nucleus

284591:YALI0 E19701g
gene id: 284591:YALI0_E19701g
uniprot id: Q6C5A4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

284591:YALI0 B16104g
gene id: 284591:YALI0_B16104g
uniprot id: Q6CEF3
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.

284591:YALI0 F22341g
gene id: 284591:YALI0_F22341g
uniprot id: Q6C0R7
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 D06017g
gene id: 284591:YALI0_D06017g
uniprot id: Q6CA44
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

284591:YALI0 D09845g
gene id: 284591:YALI0_D09845g
uniprot id: Q6C9M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MRG family.
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
messages: Nucleus

284591:YALI0 F09669g
gene id: 284591:YALI0_F09669g
uniprot id: Q6C294
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

284591:YALI0 C23232g
gene id: 284591:YALI0_C23232g
uniprot id: Q6CAZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

284591:YALI0 A18986g
gene id: 284591:YALI0_A18986g
uniprot id: Q6CGI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LU7TM family.
messages: Membrane

284591:YALI0 D08998g
gene id: 284591:YALI0_D08998g
uniprot id: Q6C9R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

284591:YALI0 C24255g
gene id: 284591:YALI0_C24255g
uniprot id: Q6CAU5
names: Similarity
messages: Belongs to the PdxS/SNZ family.

284591:YALI0 E33957g
gene id: 284591:YALI0_E33957g
uniprot id: Q6C3L0
names: Similarity
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.

284591:YALI0 B14883g
gene id: 284591:YALI0_B14883g
uniprot id: Q6CEK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
messages: Chromosome
messages: Component of the COMPASS (Set1C) complex.
messages: Nucleus

284591:YALI0 E32725g
gene id: 284591:YALI0_E32725g
uniprot id: Q6C3R4
names: Similarity
messages: Belongs to the MUB1/samB family.

284591:YALI0 E29711g
gene id: 284591:YALI0_E29711g
uniprot id: Q6C448
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

284591:YALI0 E12595g
gene id: 284591:YALI0_E12595g
uniprot id: Q6C642
names: Similarity
messages: Belongs to the AccD/PCCB family.

284591:YALI0 E05225g
gene id: 284591:YALI0_E05225g
uniprot id: Q6C6Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

284591:YALI0 D26103g
gene id: 284591:YALI0_D26103g
uniprot id: Q6C7R2
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

284591:YALI0 F02585g
gene id: 284591:YALI0_F02585g
uniprot id: Q6C352
names: Similarity
messages: Belongs to the AAA ATPase family.

284591:YALI0 C23617g
gene id: 284591:YALI0_C23617g
uniprot id: P41943
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: By acetic acid and ethanol.
messages: Membrane
messages: Plays a role in the adaptation of cell metabolism to the utilization of acetic acid, possibly by inhibiting an anion-transporting ATPase and affecting the plasma membrane H(+)-ATPase. May be indirectly involved in the repression of genes encoding glyoxylate cycle enzymes.

284591:YALI0 D11396g
gene id: 284591:YALI0_D11396g
uniprot id: Q6C9G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

284591:YALI0 E09845g
gene id: 284591:YALI0_E09845g
uniprot id: Q6C6G0
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

284591:YALI0 B05522g
gene id: 284591:YALI0_B05522g
uniprot id: Q6CFM9
names: Similarity
messages: Belongs to the peptidase M18 family.

284591:YALI0 E17281g
gene id: 284591:YALI0_E17281g
uniprot id: Q6C5K6
names: Similarity
messages: Belongs to the WrbA family.

284591:YALI0 C21780g
gene id: 284591:YALI0_C21780g
uniprot id: Q6CB56
names: Similarity
messages: Belongs to the small Tim family.

284591:YALI0 C07436g
gene id: 284591:YALI0_C07436g
uniprot id: Q6CCQ7
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

284591:YALI0 E34672g
gene id: 284591:YALI0_E34672g
uniprot id: Q6C3I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 F20856g
gene id: 284591:YALI0_F20856g
uniprot id: Q6C0Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family.
messages: Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. Binding to F-actin is regulated by tropomyosin. It is the major component of intranuclear and cytoplasmic actin rods. Required for accumulation of actin at the cell division site via depolymerizing actin at the cell ends. In association with myosin II has a role in the assembly of the contractile ring via severing actin filaments. Involved in the maintenance of the contractile ring once formed. In association with profilin and capping protein, has a role in the mitotic reorganization of the actin cytoskeleton (By similarity).
messages: Cytoplasm
messages: Nucleus matrix
messages: cytoskeleton

284591:YALI0 B09273g
gene id: 284591:YALI0_B09273g
uniprot id: Q6CF88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.
messages: Membrane
messages: Vacuole membrane

284591:YALI0 F04169g
gene id: 284591:YALI0_F04169g
uniprot id: Q6C2Y0
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

284591:YALI0 E16456g
gene id: 284591:YALI0_E16456g
uniprot id: Q6C5P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284591:YALI0 E15202g
gene id: 284591:YALI0_E15202g
uniprot id: Q6C5U0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284591:YALI0 E31691g
gene id: 284591:YALI0_E31691g
uniprot id: Q6C3W3
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

284591:YALI0 F08679g
gene id: 284591:YALI0_F08679g
uniprot id: Q6C2E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

284591:YALI0 F20900g
gene id: 284591:YALI0_F20900g
uniprot id: Q6C0X8
names: Similarity
messages: Belongs to the ketopantoate reductase family.

284591:YALI0 A01958g
gene id: 284591:YALI0_A01958g
uniprot id: Q6CI42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 B14289g
gene id: 284591:YALI0_B14289g
uniprot id: Q6CEN5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

284591:YALI0 C09889g
gene id: 284591:YALI0_C09889g
uniprot id: Q6CCF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

284591:YALI0 D26532g
gene id: 284591:YALI0_D26532g
uniprot id: Q6C7P1
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion

284591:YALI0 F13189g
gene id: 284591:YALI0_F13189g
uniprot id: P42781
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family. Furin subfamily.
messages: Membrane

284591:YALI0 B15708g
gene id: 284591:YALI0_B15708g
uniprot id: Q6CEG9
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

284591:YALI0 E04719g
gene id: 284591:YALI0_E04719g
uniprot id: Q6C708
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

284591:YALI0 E14729g
gene id: 284591:YALI0_E14729g
uniprot id: Q6C5V9
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C06460g
gene id: 284591:YALI0_C06460g
uniprot id: Q6CCU4
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

284591:YALI0 D10505g
gene id: 284591:YALI0_D10505g
uniprot id: Q6C9K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm.
messages: nucleolus

284591:YALI0 F09339g
gene id: 284591:YALI0_F09339g
uniprot id: Q6C2B0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

284591:YALI0 E04675g
gene id: 284591:YALI0_E04675g
uniprot id: Q6C710
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autoacetylation at Lys-285 is required for proper function.
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z (By similarity). Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, and histone H2A to form H2AK4ac and H2AK7ac (By similarity). The NuA4 complex is involved in the DNA damage response and is required for chromosome segregation. The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) through homologous recombination (By similarity). Recruitment to promoters depends on H3K4me. Also acetylates non-histone proteins (By similarity). In addition to protein acetyltransferase, can use different acyl-CoA substrates, such as 2-hydroxyisobutanoyl-CoA (2-hydroxyisobutyryl-CoA) or (2E)-butenoyl-CoA (crotonyl-CoA), and is able to mediate protein 2-hydroxyisobutyrylation and crotonylation, respectively (By similarity).
messages: Chromosome
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus

284591:YALI0 B17688g
gene id: 284591:YALI0_B17688g
uniprot id: Q6CE86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
messages: Endoplasmic reticulum membrane

284591:YALI0 F19272g
gene id: 284591:YALI0_F19272g
uniprot id: Q6C148
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

284591:YALI0 C15488g
gene id: 284591:YALI0_C15488g
uniprot id: Q6CBU1
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F04532g
gene id: 284591:YALI0_F04532g
uniprot id: Q6C2W7
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

284591:YALI0 D19558g
gene id: 284591:YALI0_D19558g
uniprot id: Q6C8H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

284591:YALI0 B10472g
gene id: 284591:YALI0_B10472g
uniprot id: Q6CF40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF7 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus

284591:YALI0 B06732g
gene id: 284591:YALI0_B06732g
uniprot id: Q6CFI4
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D13178g
gene id: 284591:YALI0_D13178g
uniprot id: Q6C982
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP6 subfamily.
messages: Component of the SWR1 chromatin remodeling complex.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability (By similarity).
messages: Cytoplasm
messages: Nucleus
messages: cytoskeleton

284591:YALI0 C23562g
gene id: 284591:YALI0_C23562g
uniprot id: Q6CAX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglutaminase-like superfamily. PNGase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins (By similarity).

284591:YALI0 D05467g
gene id: 284591:YALI0_D05467g
uniprot id: F2Z6F1
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.

284591:YALI0 B22506g
gene id: 284591:YALI0_B22506g
uniprot id: Q6CDN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284591:YALI0 B01386g
gene id: 284591:YALI0_B01386g
uniprot id: Q6CG28
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

284591:YALI0 C23793g
gene id: 284591:YALI0_C23793g
uniprot id: Q6CAW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

284591:YALI0 E21956g
gene id: 284591:YALI0_E21956g
uniprot id: Q6C512
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AEP2 family.
messages: Binds to the 5'UTR of the OLI1 mRNA.
messages: Mitochondrion
messages: Required for translation of the mitochondrial OLI1 transcript coding for the mitochondrial ATP synthase subunit 9.

284591:YALI0 A02607g
gene id: 284591:YALI0_A02607g
uniprot id: Q6CI12
names: Similarity
messages: Belongs to the peptidase M20A family.

284591:YALI0 F01254g
gene id: 284591:YALI0_F01254g
uniprot id: Q6C3A6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A15081g
gene id: 284591:YALI0_A15081g
uniprot id: Q6CGX8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

284591:YALI0 F02497g
gene id: 284591:YALI0_F02497g
uniprot id: Q6C354
names: Activity Regulation
names: Disruption Phenotype
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PrpD family.
messages: Component of the methylcitrate cycle that catalyzes the dehydration of 2-methylcitrate to 2-methyl-cis-aconitate. The methylcitrate cycle is a metabolic pathway for the consumption of propionic acid.
messages: Leads to lipid accumulation and increased citrate production when biodiesel-derived waste glycerol is used as substrate.
messages: Mitochondrion
messages: Monomer.
messages: Several bivalent metal ions, such as nickel, copper, zinc, mercury, and lead, inhibit the activity to some extent. Inhibited by structural analogs such as citrate, cis-aconitate, isocitrate, 2-methylisocitrate, tricarballylate and fluorocitrate, but not by trans-aconitate or adipate.
messages: Slightly repressed by glucose.

284591:YALI0 D10104g
gene id: 284591:YALI0_D10104g
uniprot id: Q6C9L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

284591:YALI0 B23188g
gene id: 284591:YALI0_B23188g
uniprot id: Q6CDK7
names: Similarity
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.

284591:YALI0 D16709g
gene id: 284591:YALI0_D16709g
uniprot id: Q6C8V4
names: Similarity
messages: Belongs to the sulfiredoxin family.

284591:YALI0 C14806g
gene id: 284591:YALI0_C14806g
uniprot id: Q6CBW8
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

284591:YALI0 E27027g
gene id: 284591:YALI0_E27027g
uniprot id: Q6C4G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

284591:YALI0 E08646g
gene id: 284591:YALI0_E08646g
uniprot id: Q6C6K8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

284591:YALI0 B12122g
gene id: 284591:YALI0_B12122g
uniprot id: W0TYP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDA2 family.
messages: Cell projection

284591:YALI0 D04246g
gene id: 284591:YALI0_D04246g
uniprot id: Q6CAB6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A18315g
gene id: 284591:YALI0_A18315g
uniprot id: Q6CGL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SGF11 family.
messages: Component of the 1.8 MDa SAGA transcription coactivator-HAT complex. SAGA is built of 5 distinct domains with specialized functions. Within the SAGA complex, SUS1, SGF11, SGF73 and UBP8 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with SGF73, SUS1 and UBP8.
messages: Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). Involved in transcriptional regulation of a subset of SAGA-regulated genes. Within the SAGA complex, participates in a subcomplex, that specifically deubiquitinates histones H2B.
messages: Nucleus

284591:YALI0 B12870g
gene id: 284591:YALI0_B12870g
uniprot id: Q6CEU4
names: Similarity
messages: Belongs to the type-1 OGG1 family.

284591:YALI0 D08866g
gene id: 284591:YALI0_D08866g
uniprot id: Q6C9R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFH5 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Microsome membrane
messages: Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane. Heme-binding protein that may play a role in organic oxidant-induced stress responses.

284591:YALI0 E25179g
gene id: 284591:YALI0_E25179g
uniprot id: Q6C4M8
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F20416g
gene id: 284591:YALI0_F20416g
uniprot id: Q6C100
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).

284591:YALI0 C15114g
gene id: 284591:YALI0_C15114g
uniprot id: Q6CBV8
names: Similarity
messages: Belongs to the cyclin family.

284591:YALI0 D12518g
gene id: 284591:YALI0_D12518g
uniprot id: Q6C9B4
names: Similarity
messages: Belongs to the cullin family.

284591:YALI0 D08976g
gene id: 284591:YALI0_D08976g
uniprot id: Q6C9R4
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

284591:YALI0 E14751g
gene id: 284591:YALI0_E14751g
uniprot id: Q6C5V8
names: Similarity
messages: Belongs to the anthranilate synthase component I family.

284591:YALI0 D08419g
gene id: 284591:YALI0_D08419g
uniprot id: Q6C9T9
names: Similarity
messages: Belongs to the PPP4R2 family.

284591:YALI0 D10131g
gene id: 284591:YALI0_D10131g
uniprot id: Q6C9L5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

284591:YALI0 E34903g
gene id: 284591:YALI0_E34903g
uniprot id: Q6C3H0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D22066g
gene id: 284591:YALI0_D22066g
uniprot id: Q6C875
names: Similarity
messages: Belongs to the PP2C family.

284591:YALI0 D20614g
gene id: 284591:YALI0_D20614g
uniprot id: Q6C8D2
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

284591:YALI0 B19624g
gene id: 284591:YALI0_B19624g
uniprot id: Q6CE09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-3 family.
messages: Membrane
messages: Peroxisome membrane

284591:YALI0 C23188g
gene id: 284591:YALI0_C23188g
uniprot id: Q6CAZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

284591:YALI0 F11143g
gene id: 284591:YALI0_F11143g
uniprot id: Q6C238
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EXO84 family.
messages: Component of the exocyst complex.
messages: Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Plays a role in both the assembly of the exocyst and the polarization of this complex to specific sites of the plasma membrane for exocytosis. Also involved in assembly of the spliceosome (By similarity).
messages: secretory vesicle

284591:YALI0 E09449g
gene id: 284591:YALI0_E09449g
uniprot id: Q6C6H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

284591:YALI0 C16797g
gene id: 284591:YALI0_C16797g
uniprot id: Q6CBP3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

284591:YALI0 C04367g
gene id: 284591:YALI0_C04367g
uniprot id: Q6CD24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

284591:YALI0 C03872g
gene id: 284591:YALI0_C03872g
uniprot id: Q6CD45
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

284591:YALI0 E06831g
gene id: 284591:YALI0_E06831g
uniprot id: Q6C6R8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Coreceptor required for the peroxisomal import of proteins containing a C-terminal PTS2-type peroxisomal targeting signal, such as 3-oxoacyl-CoA thiolase (PubMed:9679140, PubMed:11606420). Acts via its interaction with PEX7, promoting association between PEX7 bound to cargo proteins and the PEX13-PEX14 docking complex (PubMed:9679140, PubMed:11606420). PEX20 along with PEX7 and PTS2-containing cargo proteins are tranlocated into peroxisomes by passing through the PEX13-PEX14 docking complex (PubMed:31042004). PEX20 coreceptor is then retrotranslocated into the cytosol, leading to release of bound cargo in the peroxisome matrix, and reset for a subsequent peroxisome import cycle (By similarity). Also mediates peroxisomal import of proteins that do not contain PTS1- or PTS2-type peroxisomal targeting signals, such as acyl-CoA oxidases (Aox) izozymes (PubMed:31042004). Import of acyl-CoA oxidases (Aox) izozymes is independent of PEX7 (PubMed:31042004).
messages: Interacts (via WxxxF/Y and LVxEF motifs) with PEX14; promoting translocation through the PEX13-PEX14 docking complex (PubMed:31042004). Interacts with PEX7 (PubMed:31042004, PubMed:11606420).
messages: Monoubiquitinated at Cys-4 by PEX2 during PEX20 passage through the PEX2-PEX10-PEX12 retrotranslocation channel: monoubiquitination acts as a signal for PEX20 extraction and is required for proper export from peroxisomes and recycling (By similarity). When PEX5 recycling is compromised, polyubiquitinated at Lys-15 by PEX10 during its passage through the retrotranslocation channel, leading to its degradation (By similarity).
messages: Peroxisome matrix
messages: The WxxxF/Y motifs mediate interaction with PEX14, promoting association with the PEX13-PEX14 docking complex.
messages: cytosol

284591:YALI0 A17534g
gene id: 284591:YALI0_A17534g
uniprot id: Q6CGP4
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B04048g
gene id: 284591:YALI0_B04048g
uniprot id: Q6CFT5
names: Similarity
messages: Belongs to the IST1 family.

284591:YALI0 A00869g
gene id: 284591:YALI0_A00869g
uniprot id: Q6CI79
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B11440g
gene id: 284591:YALI0_B11440g
uniprot id: Q6CF02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ALG14 family.
messages: Endoplasmic reticulum membrane
messages: Heterodimer with ALG13 to form a functional enzyme.
messages: Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway (By similarity).
messages: Nucleus membrane

284591:YALI0 A10615g
gene id: 284591:YALI0_A10615g
uniprot id: Q6CHB1
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

284591:YALI0 D19008g
gene id: 284591:YALI0_D19008g
uniprot id: Q6C8K0
names: Function
names: Subcellular Location Annotation
messages: May act as a zinc-influx transporter.
messages: Membrane

284591:YALI0 E17017g
gene id: 284591:YALI0_E17017g
uniprot id: Q6C5L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 F22737g
gene id: 284591:YALI0_F22737g
uniprot id: Q6C0P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Heterotetramer; composed of two copies of TRM6 and two copies of TRM61.
messages: Nucleus

284591:YALI0 E27852g
gene id: 284591:YALI0_E27852g
uniprot id: Q6C4C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

284591:YALI0 A08129g
gene id: 284591:YALI0_A08129g
uniprot id: Q6CHJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 D05159g
gene id: 284591:YALI0_D05159g
uniprot id: Q6CA79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm

284591:YALI0 E09015g
gene id: 284591:YALI0_E09015g
uniprot id: Q6C6J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

284591:YALI0 F09746g
gene id: 284591:YALI0_F09746g
uniprot id: Q6C292
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

284591:YALI0 C08140g
gene id: 284591:YALI0_C08140g
uniprot id: Q6CCM7
names: Similarity
messages: Belongs to the wetA family.

284591:YALI0 F14751g
gene id: 284591:YALI0_F14751g
uniprot id: Q6C1N5
names: Similarity
messages: Belongs to the TBCC family.

284591:YALI0 C07458g
gene id: 284591:YALI0_C07458g
uniprot id: Q707Y0
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TALE/M-ATYP homeobox family.
messages: Forms a heterodimer with A1.
messages: Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion. Transcriptional corepressor that acts in conjunction with A1 to repress transcription of haploid-specific genes (By similarity).
messages: Nucleus
messages: Only present in B-cells and in A/B diploid cells.

284591:YALI0 D25542g
gene id: 284591:YALI0_D25542g
uniprot id: Q6C7T4
names: Similarity
messages: Belongs to the CoA-transferase III family.

284591:YALI0 D06820g
gene id: 284591:YALI0_D06820g
uniprot id: Q6CA09
names: Subcellular Location Annotation
messages: Cytoplasm

284591:YALI0 A06787g
gene id: 284591:YALI0_A06787g
uniprot id: Q6CHP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.
messages: Endoplasmic reticulum membrane

284591:YALI0 F17842g
gene id: 284591:YALI0_F17842g
uniprot id: Q6C1A8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

284591:YALI0 B01980g
gene id: 284591:YALI0_B01980g
uniprot id: Q6CG06
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.

284591:YALI0 F02937g
gene id: 284591:YALI0_F02937g
uniprot id: Q6C336
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

284591:YALI0 B10406g
gene id: 284591:YALI0_B10406g
uniprot id: Q6CF43
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

284591:YALI0 E14036g
gene id: 284591:YALI0_E14036g
uniprot id: Q6C5Y6
names: Subcellular Location Annotation
messages: Cytoplasm

284591:YALI0 A19976g
gene id: 284591:YALI0_A19976g
uniprot id: Q6CGE6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the calcineurin regulatory subunit family.
messages: Composed of a catalytic subunit (A) and a regulatory subunit (B).
messages: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity (By similarity).
messages: This protein has four functional calcium-binding sites.

284591:YALI0 D26081g
gene id: 284591:YALI0_D26081g
uniprot id: Q6C7R3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C22187g
gene id: 284591:YALI0_C22187g
uniprot id: Q6CB37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BIG1 family.
messages: Endoplasmic reticulum membrane
messages: Required for normal beta-1,6-glucan synthesis.

284591:YALI0 E03806g
gene id: 284591:YALI0_E03806g
uniprot id: Q6C748
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynurenine formamidase family.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
messages: Homodimer.
messages: The main chain amide nitrogen atoms of the second glycine and its adjacent residue in the HGGXW motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.

284591:YALI0 F30701g
gene id: 284591:YALI0_F30701g
uniprot id: Q6BZV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

284591:YALI0 D09955g
gene id: 284591:YALI0_D09955g
uniprot id: Q6C9M4
names: Function
names: Similarity
messages: Belongs to the SNU71 family.
messages: Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway.

284591:YALI0 D17270g
gene id: 284591:YALI0_D17270g
uniprot id: Q6C8S8
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 B15862g
gene id: 284591:YALI0_B15862g
uniprot id: Q6CEG3
names: Similarity
messages: Belongs to the VPS72/YL1 family.

284591:YALI0 F10483g
gene id: 284591:YALI0_F10483g
uniprot id: Q6C265
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 22 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284591:YALI0 E16478g
gene id: 284591:YALI0_E16478g
uniprot id: Q6C5N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 D07370g
gene id: 284591:YALI0_D07370g
uniprot id: Q6C9Y4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Cytoplasm

284591:YALI0 E15125g
gene id: 284591:YALI0_E15125g
uniprot id: Q6C5U4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

284591:YALI0 E34067g
gene id: 284591:YALI0_E34067g
uniprot id: Q6C3K5
names: Similarity
messages: Belongs to the protein kinase superfamily.

284591:YALI0 D14916g
gene id: 284591:YALI0_D14916g
uniprot id: Q6C923
names: Similarity
messages: Belongs to the TRL1 family.

284591:YALI0 C16522g
gene id: 284591:YALI0_C16522g
uniprot id: Q6CBQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 D10901g
gene id: 284591:YALI0_D10901g
uniprot id: Q6C9I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the ISY1 family.
messages: Cytoplasm
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284591:YALI0 E24013g
gene id: 284591:YALI0_E24013g
uniprot id: Q6C4S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

284591:YALI0 B21098g
gene id: 284591:YALI0_B21098g
uniprot id: Q6CDU6
names: Similarity
messages: Belongs to the TPA1 family.

284591:YALI0 E10043g
gene id: 284591:YALI0_E10043g
uniprot id: Q6C6F1
names: Similarity
messages: Belongs to the RCAN family.

284591:YALI0 F06644g
gene id: 284591:YALI0_F06644g
uniprot id: Q6C2M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

284591:YALI0 E19008g
gene id: 284591:YALI0_E19008g
uniprot id: Q6C5D3
names: Similarity
names: Subunit
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.
messages: Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.

284591:YALI0 B17303g
gene id: 284591:YALI0_B17303g
uniprot id: B5FVB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD3 family.
messages: Nucleus
messages: kinetochore
messages: spindle

284591:YALI0 D16313g
gene id: 284591:YALI0_D16313g
uniprot id: Q6C8W7
names: Similarity
messages: Belongs to the CWC22 family.

284591:YALI0 A08151g
gene id: 284591:YALI0_A08151g
uniprot id: Q6CHJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

284591:YALI0 E01078g
gene id: 284591:YALI0_E01078g
uniprot id: Q6C7G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.
messages: Cytoplasm
messages: Monomer.

284591:YALI0 A17875g
gene id: 284591:YALI0_A17875g
uniprot id: Q6CGN3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

284591:YALI0 C06347g
gene id: 284591:YALI0_C06347g
uniprot id: Q6CCU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MON1/SAND family.
messages: Prevacuolar compartment membrane
messages: Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.
messages: Vacuole membrane
messages: multivesicular body membrane

284591:YALI0 B11044g
gene id: 284591:YALI0_B11044g
uniprot id: Q6CF18
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Inhibited by organophosphorus esters.
messages: Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity).

284591:YALI0 C14498g
gene id: 284591:YALI0_C14498g
uniprot id: Q6CBY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284591:YALI0 F18524g
gene id: 284591:YALI0_F18524g
uniprot id: Q6C180
names: Similarity
messages: Belongs to the VPS37 family.

284591:YALI0 F15895g
gene id: 284591:YALI0_F15895g
uniprot id: Q6C1I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex SPC34 family.
messages: Nucleus
messages: kinetochore
messages: spindle

284591:YALI0 F03817g
gene id: 284591:YALI0_F03817g
uniprot id: Q6C2Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
messages: Nucleus

284591:YALI0 D12749g
gene id: 284591:YALI0_D12749g
uniprot id: Q6C9A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 C04477g
gene id: 284591:YALI0_C04477g
uniprot id: Q6CD19
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B20680g
gene id: 284591:YALI0_B20680g
uniprot id: Q6CDW5
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

284591:YALI0 F17116g
gene id: 284591:YALI0_F17116g
uniprot id: Q6C1E1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

284591:YALI0 C08723g
gene id: 284591:YALI0_C08723g
uniprot id: Q6CCK1
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

284591:YALI0 D00737g
gene id: 284591:YALI0_D00737g
uniprot id: F2Z6C0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

284591:YALI0 C17303g
gene id: 284591:YALI0_C17303g
uniprot id: Q6CBM4
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A15950g
gene id: 284591:YALI0_A15950g
uniprot id: Q6CGV2
names: Similarity
messages: In the C-terminal section; belongs to the histidinol dehydrogenase family.

284591:YALI0 C06061g
gene id: 284591:YALI0_C06061g
uniprot id: Q6CCW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

284591:YALI0 D20724g
gene id: 284591:YALI0_D20724g
uniprot id: Q6C8C7
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

284591:YALI0 E27830g
gene id: 284591:YALI0_E27830g
uniprot id: Q6C4C8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

284591:YALI0 F23221g
gene id: 284591:YALI0_F23221g
uniprot id: Q6C0N3
names: Similarity
messages: Belongs to the threonine synthase family.

284591:YALI0 F31317g
gene id: 284591:YALI0_F31317g
uniprot id: Q6BZS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

284591:YALI0 F20812g
gene id: 284591:YALI0_F20812g
uniprot id: Q6C0Y2
names: Similarity
messages: Belongs to the PITHD1 family.

284591:YALI0 E18480g
gene id: 284591:YALI0_E18480g
uniprot id: Q6C5F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

284591:YALI0 A14366g
gene id: 284591:YALI0_A14366g
uniprot id: Q6CH07
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

284591:YALI0 F11561g
gene id: 284591:YALI0_F11561g
uniprot id: Q6C220
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.

284591:YALI0 C00627g
gene id: 284591:YALI0_C00627g
uniprot id: Q6CDG9
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F12925g
gene id: 284591:YALI0_F12925g
uniprot id: Q6C1W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

284591:YALI0 E20361g
gene id: 284591:YALI0_E20361g
uniprot id: Q6C579
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.

284591:YALI0 A15774g
gene id: 284591:YALI0_A15774g
uniprot id: Q6CGV6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B14465g
gene id: 284591:YALI0_B14465g
uniprot id: Q6CEM7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

284591:YALI0 F08459g
gene id: 284591:YALI0_F08459g
uniprot id: Q6C2F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

284591:YALI0 F15433g
gene id: 284591:YALI0_F15433g
uniprot id: Q6C1K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 B19668g
gene id: 284591:YALI0_B19668g
uniprot id: Q6CE07
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DP1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Oligomer.
messages: Required to generate and maintain the structure of the tubular endoplasmic reticulum network and the vacuole. Induces high curvature in membranes and causes membrane tubule formation. Involved in membrane/vesicle trafficking.
messages: The short lumenal loops between transmembrane domains 1 and 2 and between transmembrane domains 3 and 4 may impart a wedge-like configuration, thus deforming membranes.

284591:YALI0 E24035g
gene id: 284591:YALI0_E24035g
uniprot id: Q6C4S8
names: Similarity
messages: Belongs to the TFIIB family.

284591:YALI0 D25058g
gene id: 284591:YALI0_D25058g
uniprot id: Q6C7V4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity).
messages: Forms a stable heterodimer with SPT16. The SPT16-POB3 dimer weakly associates with multiple molecules of NHP6 to form the FACT complex (By similarity).
messages: In contrast to the orthologous protein in animals and plants, this protein does not contain a HMG box DNA-binding domain. This function may instead be provided by the HMG box of the associated NHP6 protein in the FACT complex of fungi.
messages: Nucleus

284591:YALI0 D06545g
gene id: 284591:YALI0_D06545g
uniprot id: Q6CA22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 E03344g
gene id: 284591:YALI0_E03344g
uniprot id: Q6C767
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.

284591:YALI0 C13112g
gene id: 284591:YALI0_C13112g
uniprot id: Q6CC27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

284591:YALI0 F26609g
gene id: 284591:YALI0_F26609g
uniprot id: Q6C097
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethan group.

284591:YALI0 A06105g
gene id: 284591:YALI0_A06105g
uniprot id: Q6CHQ9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

284591:YALI0 D11770g
gene id: 284591:YALI0_D11770g
uniprot id: Q6C9E8
names: Similarity
messages: Belongs to the AAA ATPase family.

284591:YALI0 C15873g
gene id: 284591:YALI0_C15873g
uniprot id: Q6CBS8
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

284591:YALI0 A19162g
gene id: 284591:YALI0_A19162g
uniprot id: Q6CGH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-T/CNN1 family.
messages: Nucleus

284591:YALI0 E24673g
gene id: 284591:YALI0_E24673g
uniprot id: Q6C4P9
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

284591:YALI0 E29139g
gene id: 284591:YALI0_E29139g
uniprot id: Q6C474
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284591:YALI0 F31405g
gene id: 284591:YALI0_F31405g
uniprot id: Q6BZR8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

284591:YALI0 F18194g
gene id: 284591:YALI0_F18194g
uniprot id: Q6C195
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SSU72 phosphatase family.
messages: Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. SSU72 is required for 3'-end formation of snoRNAs (By similarity).
messages: Component of the cleavage and polyadenylation factor (CPF) complex.
messages: Nucleus
messages: Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1).

284591:YALI0 B17732g
gene id: 284591:YALI0_B17732g
uniprot id: Q6CE84
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

284591:YALI0 E08580g
gene id: 284591:YALI0_E08580g
uniprot id: Q6C6L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRM1 family.
messages: Cell membrane
messages: Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.

284591:YALI0 E22198g
gene id: 284591:YALI0_E22198g
uniprot id: Q6C504
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F14729g
gene id: 284591:YALI0_F14729g
uniprot id: Q6C1N6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

284591:YALI0 B23276g
gene id: 284591:YALI0_B23276g
uniprot id: Q6CDK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

284591:YALI0 F24519g
gene id: 284591:YALI0_F24519g
uniprot id: Q6C0H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

284591:YALI0 C04455g
gene id: 284591:YALI0_C04455g
uniprot id: Q6CD20
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F25597g
gene id: 284591:YALI0_F25597g
uniprot id: Q6C0D8
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C07678g
gene id: 284591:YALI0_C07678g
uniprot id: Q6CCP6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E07788g
gene id: 284591:YALI0_E07788g
uniprot id: Q6C6N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism.

284591:YALI0 A14707g
gene id: 284591:YALI0_A14707g
uniprot id: Q6CGZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

284591:YALI0 E04466g
gene id: 284591:YALI0_E04466g
uniprot id: Q6C720
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR1 family.
messages: Membrane

284591:YALI0 D07194g
gene id: 284591:YALI0_D07194g
uniprot id: Q6C9Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284591:YALI0 F17534g
gene id: 284591:YALI0_F17534g
uniprot id: Q6C1C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

284591:YALI0 B06831g
gene id: 284591:YALI0_B06831g
uniprot id: Q6CFH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase d subunit family.
messages: F-type ATP synthases have 2 components, the catalytic core F(1) and the membrane-embedded component F(0), linked together by a central stalk and a peripheral stalk (PubMed:27373333). The central stalk, also called rotor shaft, is often seen as part of F(1) (PubMed:27373333). The peripheral stalk is seen as part of F(0) (PubMed:27373333). F(0) contains the membrane channel next to the rotor (PubMed:27373333). F-type ATP synthases form dimers but each monomer functions independently in ATP generation (PubMed:27373333). The dimer consists of 17 different polypeptides: ATP1 (subunit alpha, 3 molecules per monomer, part of F(1)), ATP2 (subunit beta, 3 copies per monomer, part of F(1)), ATP3 (subunit gamma, part of the central stalk), ATP4 (subunit b, part of the peripheral stalk), ATP5/OSCP (subunit 5/OSCP, part of the peripheral stalk), ATP6 (subunit a, part of the peripheral stalk), ATP7 (subunit d, part of the peripheral stalk), ATP8 (subunit 8, part of the peripheral stalk), OLI1 (subunit c, part of the rotor, 10 molecules per monomer), ATP14 (subunit h, part of the peripheral stalk), ATP15 (subunit epsilon, part of the central stalk), ATP16 (subunit delta, part of the central stalk), ATP17 (subunit f, part of the peripheral stalk), ATP18 (subunit i/j, part of the peripheral stalk), ATP19 (subunit k, dimer-specific, at interface between monomers), ATP20 (subunit g, at interface between monomers), TIM11 (subunit e, at interface between monomers) (PubMed:27373333, PubMed:25759169).
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169). F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27373333). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (PubMed:27373333). Part of the complex F(0) domain and the peripheral stalk, which acts as a stator to hold the catalytic alpha/ATP1(3)beta/ATP2(3) subcomplex and subunit a/ATP6 static relative to the rotary elements (PubMed:27373333).
messages: Mitochondrion inner membrane

284591:YALI0 C21406g
gene id: 284591:YALI0_C21406g
uniprot id: Q6CB72
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284591:YALI0 E10483g
gene id: 284591:YALI0_E10483g
uniprot id: Q6C6D0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E22737g
gene id: 284591:YALI0_E22737g
uniprot id: Q6C4Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG16 family.
messages: Homodimer (By similarity). Part of the ATG5-ATG12/ATG16 complex. Several units of each may be present in this complex (By similarity).
messages: Preautophagosomal structure membrane
messages: Stabilizes the ATG5-ATG12 conjugate which is necessary for autophagy. The ATG5-ATG12/ATG16 complex is required for efficient promotion of ATG8-conjugation to phosphatidylethanolamine and ATG8 localization to the pre-autophagosomal structure (PAS). Recruits also ATG3 to the PAS. Involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress (By similarity).

284591:YALI0 E13640g
gene id: 284591:YALI0_E13640g
uniprot id: Q6C602
names: Similarity
messages: Belongs to the cyclin family.

284591:YALI0 E29337g
gene id: 284591:YALI0_E29337g
uniprot id: Q6C465
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

284591:YALI0 B04774g
gene id: 284591:YALI0_B04774g
uniprot id: Q6CFQ5
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

284591:YALI0 C19195g
gene id: 284591:YALI0_C19195g
uniprot id: Q6CBG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 E17369g
gene id: 284591:YALI0_E17369g
uniprot id: Q6C5K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL67 family.
messages: Mitochondrion
messages: Nucleus
messages: Transcription factor involved in regulation of RNA polymerase II-dependent transcription. Also involved in regulation of mitochondrial DNA recombination, maintenance and repair, and generation of homoplasmic cells (By similarity).

284591:YALI0 E26587g
gene id: 284591:YALI0_E26587g
uniprot id: Q6C4I1
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

284591:YALI0 A08426g
gene id: 284591:YALI0_A08426g
uniprot id: Q6CHI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

284591:YALI0 E23452g
gene id: 284591:YALI0_E23452g
uniprot id: Q6C4V2
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

284591:YALI0 D18568g
gene id: 284591:YALI0_D18568g
uniprot id: Q6C8M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

284591:YALI0 C02783g
gene id: 284591:YALI0_C02783g
uniprot id: Q6CD90
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B14267g
gene id: 284591:YALI0_B14267g
uniprot id: Q6CEN6
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

284591:YALI0 B10516g
gene id: 284591:YALI0_B10516g
uniprot id: Q6CF38
names: Similarity
messages: Belongs to the CAP family.

284591:YALI0 B08448g
gene id: 284591:YALI0_B08448g
uniprot id: Q6CFC0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F24277g
gene id: 284591:YALI0_F24277g
uniprot id: Q6C0J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

284591:YALI0 C18475g
gene id: 284591:YALI0_C18475g
uniprot id: Q9HFD0
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 11 family.

284591:YALI0 B16258g
gene id: 284591:YALI0_B16258g
uniprot id: Q6CEE6
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

284591:YALI0 E13035g
gene id: 284591:YALI0_E13035g
uniprot id: Q6C628
names: Similarity
messages: Belongs to the peptidase M24 family.

284591:YALI0 F24365g
gene id: 284591:YALI0_F24365g
uniprot id: Q6C0I6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

284591:YALI0 C16566g
gene id: 284591:YALI0_C16566g
uniprot id: Q6CBQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

284591:YALI0 E32571g
gene id: 284591:YALI0_E32571g
uniprot id: Q6C3S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nudE family.
messages: Required for nuclear migration.
messages: Self-associates. Interacts with PAC1 (By similarity).
messages: cytoskeleton

284591:YALI0 A01782g
gene id: 284591:YALI0_A01782g
uniprot id: Q6CI47
names: Similarity
messages: Belongs to the AAR2 family.

284591:YALI0 E32901g
gene id: 284591:YALI0_E32901g
uniprot id: Q6C3Q6
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284591:YALI0 F07667g
gene id: 284591:YALI0_F07667g
uniprot id: Q6C2I3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

284591:YALI0 D05093g
gene id: 284591:YALI0_D05093g
uniprot id: Q6CA81
names: Similarity
messages: Belongs to the DNA polymerase delta/II small subunit family.

284591:YALI0 B16522g
gene id: 284591:YALI0_B16522g
uniprot id: Q6CED5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

284591:YALI0 D15620g
gene id: 284591:YALI0_D15620g
uniprot id: Q6C8Z3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

284591:YALI0 F31053g
gene id: 284591:YALI0_F31053g
uniprot id: Q6BZT4
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E27049g
gene id: 284591:YALI0_E27049g
uniprot id: Q6C4G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

284591:YALI0 C15224g
gene id: 284591:YALI0_C15224g
uniprot id: Q6CBV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

284591:YALI0 D13596g
gene id: 284591:YALI0_D13596g
uniprot id: Q6C968
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

284591:YALI0 E25113g
gene id: 284591:YALI0_E25113g
uniprot id: Q6C4N0
names: Similarity
messages: Belongs to the UPP synthase family.

284591:YALI0 A05533g
gene id: 284591:YALI0_A05533g
uniprot id: Q6CHS4
names: Similarity
messages: Belongs to the peptidase S1C family.

284591:YALI0 D02981g
gene id: 284591:YALI0_D02981g
uniprot id: Q6CAG3
names: Similarity
messages: Belongs to the peptidase S8 family.

284591:YALI0 D06413g
gene id: 284591:YALI0_D06413g
uniprot id: Q6CA28
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

284591:YALI0 F05676g
gene id: 284591:YALI0_F05676g
uniprot id: Q6C2R9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).
messages: Cytoplasm

284591:YALI0 D21362g
gene id: 284591:YALI0_D21362g
uniprot id: Q6C8A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the VPS17 family.
messages: Component of the retromer complex.
messages: Plays a role in vesicular protein sorting.

284591:YALI0 E21043g
gene id: 284591:YALI0_E21043g
uniprot id: Q6C548
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

284591:YALI0 E06479g
gene id: 284591:YALI0_E06479g
uniprot id: Q6C6T4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

284591:YALI0 B11836g
gene id: 284591:YALI0_B11836g
uniprot id: Q6CEY6
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

284591:YALI0 F12771g
gene id: 284591:YALI0_F12771g
uniprot id: Q6C1W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in cytoplasmic tRNA.

284591:YALI0 C13596g
gene id: 284591:YALI0_C13596g
uniprot id: Q6CC12
names: Similarity
messages: Belongs to the RRP7 family.

284591:YALI0 F14509g
gene id: 284591:YALI0_F14509g
uniprot id: Q6C1P6
names: Similarity
messages: Belongs to the EIS1 family.

284591:YALI0 E15884g
gene id: 284591:YALI0_E15884g
uniprot id: Q6C5R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation (By similarity).

284591:YALI0 E24717g
gene id: 284591:YALI0_E24717g
uniprot id: Q6C4P7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

284591:YALI0 E10659g
gene id: 284591:YALI0_E10659g
uniprot id: Q99156
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

284591:YALI0 C19624g
gene id: 284591:YALI0_C19624g
uniprot id: Q6CBE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
messages: Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro. Required for respiration and the maintenance of the mitochondrial compartment.
messages: Homodimer.
messages: Mitochondrion matrix

284591:YALI0 D14652g
gene id: 284591:YALI0_D14652g
uniprot id: Q6C931
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Although related to the peptidase M24 family, this protein lacks conserved active site residues suggesting that it may lack peptidase activity.
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity).
messages: Forms a stable heterodimer with POB3. The SPT16-POB3 dimer weakly associates with multiple molecules of NHP6 to form the FACT complex (By similarity).
messages: Nucleus

284591:YALI0 F31339g
gene id: 284591:YALI0_F31339g
uniprot id: Q6BZS1
names: Similarity
messages: Belongs to the EIF1AD family.

284591:YALI0 C00429g
gene id: 284591:YALI0_C00429g
uniprot id: Q6CDH7
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

284591:YALI0 B20724g
gene id: 284591:YALI0_B20724g
uniprot id: Q6CDW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

284591:YALI0 F05940g
gene id: 284591:YALI0_F05940g
uniprot id: Q6C2Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm
messages: Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity.
messages: Homohexamer. Binds to nucleic acids. Binds single-stranded DNA and RNA with higher affinity than double-stranded DNA.
messages: Mitochondrion
messages: The normal physiological role of the enzyme is unknown, but it is not essential for the viability of yeast cells. Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity. Acts as a repressor in the GAL4 regulatory system, but this does not require either the peptidase or nucleic acid-binding activities.

284591:YALI0 E33495g
gene id: 284591:YALI0_E33495g
uniprot id: Q6C3M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors GET1 and GET2, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the GET1-GET2 receptor, and returning it to the cytosol to initiate a new round of targeting. Cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER. Involved in low-level resistance to the oxyanions arsenite and arsenate, and in heat tolerance.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer. Interacts with the chloride channel protein GEF1.

284591:YALI0 E26961g
gene id: 284591:YALI0_E26961g
uniprot id: Q6C4G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

284591:YALI0 F29711g
gene id: 284591:YALI0_F29711g
uniprot id: Q6BZZ0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E26609g
gene id: 284591:YALI0_E26609g
uniprot id: Q6C4I0
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

284591:YALI0 E05423g
gene id: 284591:YALI0_E05423g
uniprot id: Q6C6X8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284591:YALI0 B05610g
gene id: 284591:YALI0_B05610g
uniprot id: Q6CFM6
names: Similarity
messages: Belongs to the GroES chaperonin family.

284591:YALI0 E02794g
gene id: 284591:YALI0_E02794g
uniprot id: Q6C788
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

284591:YALI0 D04378g
gene id: 284591:YALI0_D04378g
uniprot id: Q6CAB0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

284591:YALI0 F30261g
gene id: 284591:YALI0_F30261g
uniprot id: Q6BZX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

284591:YALI0 E17721g
gene id: 284591:YALI0_E17721g
uniprot id: Q6C5I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPI19 family.
messages: Component of the phosphatidylinositol N-acetylglucosaminyltransferase (GPI-GlcNAc transferase) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

284591:YALI0 A15884g
gene id: 284591:YALI0_A15884g
uniprot id: Q6CGV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex, which consists of NDC80, NUF2, SPC24 and SPC25.
messages: Nucleus
messages: kinetochore

284591:YALI0 A06501g
gene id: 284591:YALI0_A06501g
uniprot id: Q6CHQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

284591:YALI0 B06446g
gene id: 284591:YALI0_B06446g
uniprot id: Q6CFJ4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

284591:YALI0 F07579g
gene id: 284591:YALI0_F07579g
uniprot id: Q6C2I7
names: Similarity
messages: Belongs to the UPF0538 family.

284591:YALI0 D12903g
gene id: 284591:YALI0_D12903g
uniprot id: O59950
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

284591:YALI0 F31471g
gene id: 284591:YALI0_F31471g
uniprot id: Q6BZR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

284591:YALI0 F19536g
gene id: 284591:YALI0_F19536g
uniprot id: Q6C137
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B10824g
gene id: 284591:YALI0_B10824g
uniprot id: W0TYN9
names: Function
names: Similarity
messages: Belongs to the REXO4 family.
messages: Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.

284591:YALI0 E04807g
gene id: 284591:YALI0_E04807g
uniprot id: Q6C704
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 D02365g
gene id: 284591:YALI0_D02365g
uniprot id: Q6CAI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

284591:YALI0 B15642g
gene id: 284591:YALI0_B15642g
uniprot id: Q6CEH2
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

284591:YALI0 E05401g
gene id: 284591:YALI0_E05401g
uniprot id: Q6C6X9
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.

284591:YALI0 E07920g
gene id: 284591:YALI0_E07920g
uniprot id: Q6C6N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

284591:YALI0 E05269g
gene id: 284591:YALI0_E05269g
uniprot id: Q6C6Y5
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E13992g
gene id: 284591:YALI0_E13992g
uniprot id: Q6C5Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.
messages: Vacuole membrane

284591:YALI0 F27027g
gene id: 284591:YALI0_F27027g
uniprot id: Q6C082
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

284591:YALI0 A17424g
gene id: 284591:YALI0_A17424g
uniprot id: Q6CGP9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle (By similarity).

284591:YALI0 A20438g
gene id: 284591:YALI0_A20438g
uniprot id: Q6CGC6
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

284591:YALI0 D23661g
gene id: 284591:YALI0_D23661g
uniprot id: Q6C813
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

284591:YALI0 C05775g
gene id: 284591:YALI0_C05775g
uniprot id: Q6CCX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

284591:YALI0 E29843g
gene id: 284591:YALI0_E29843g
uniprot id: Q6C444
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
messages: Endosome

284591:YALI0 F30041g
gene id: 284591:YALI0_F30041g
uniprot id: Q6BZY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284591:YALI0 F08063g
gene id: 284591:YALI0_F08063g
uniprot id: Q6C2G6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E22715g
gene id: 284591:YALI0_E22715g
uniprot id: Q6C4Y5
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
messages: Nucleus
messages: Ubiquitination of histone H2B to form H2BK123ub1 is required for efficient DOT1 methyltransferase activity on histone H3.

284591:YALI0 C08481g
gene id: 284591:YALI0_C08481g
uniprot id: Q6CCL0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E31262g
gene id: 284591:YALI0_E31262g
uniprot id: Q6C3Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

284591:YALI0 E27654g
gene id: 284591:YALI0_E27654g
uniprot id: F2Z627
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

284591:YALI0 F17138g
gene id: 284591:YALI0_F17138g
uniprot id: Q6C1E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diphthine synthase family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

284591:YALI0 B23056g
gene id: 284591:YALI0_B23056g
uniprot id: Q6CDL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

284591:YALI0 C11649g
gene id: 284591:YALI0_C11649g
uniprot id: Q6CC80
names: Similarity
messages: Belongs to the peptidase C19 family.

284591:YALI0 F02959g
gene id: 284591:YALI0_F02959g
uniprot id: Q6C335
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B03960g
gene id: 284591:YALI0_B03960g
uniprot id: Q6CFT8
names: Subcellular Location Annotation
messages: Cytoplasm

284591:YALI0 E26939g
gene id: 284591:YALI0_E26939g
uniprot id: Q6C4G7
names: Similarity
messages: Belongs to the oligoribonuclease family.

284591:YALI0 E04763g
gene id: 284591:YALI0_E04763g
uniprot id: Q6C706
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

284591:YALI0 E24651g
gene id: 284591:YALI0_E24651g
uniprot id: Q6C4Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

284591:YALI0 E10144g
gene id: 284591:YALI0_E10144g
uniprot id: Q6C6E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

284591:YALI0 F30591g
gene id: 284591:YALI0_F30591g
uniprot id: Q6BZV5
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

284591:YALI0 D20064g
gene id: 284591:YALI0_D20064g
uniprot id: Q6C8F6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E10417g
gene id: 284591:YALI0_E10417g
uniprot id: Q6C6D3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D08250g
gene id: 284591:YALI0_D08250g
uniprot id: Q6C9U7
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.

284591:YALI0 B10274g
gene id: 284591:YALI0_B10274g
uniprot id: Q6CF49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX23 family.
messages: Mitochondrion intermembrane space
messages: Required for the assembly of cytochrome c oxidase.

284591:YALI0 B19316g
gene id: 284591:YALI0_B19316g
uniprot id: Q6CE19
names: Similarity
messages: Belongs to the peptidase S8 family.

284591:YALI0 B15488g
gene id: 284591:YALI0_B15488g
uniprot id: Q6CEH9
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A02915g
gene id: 284591:YALI0_A02915g
uniprot id: Q6CI02
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

284591:YALI0 E30129g
gene id: 284591:YALI0_E30129g
uniprot id: Q6C433
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

284591:YALI0 B05368g
gene id: 284591:YALI0_B05368g
uniprot id: Q6CFN6
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

284591:YALI0 A03575g
gene id: 284591:YALI0_A03575g
uniprot id: Q6CHY2
names: Similarity
messages: Belongs to the SKP1 family.

284591:YALI0 D20482g
gene id: 284591:YALI0_D20482g
uniprot id: Q6C8D8
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 D12408g
gene id: 284591:YALI0_D12408g
uniprot id: Q6C9B9
names: Similarity
messages: Belongs to the Rho GDI family.

284591:YALI0 F00462g
gene id: 284591:YALI0_F00462g
uniprot id: Q6C3E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

284591:YALI0 D16379g
gene id: 284591:YALI0_D16379g
uniprot id: Q6C8W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLPL family.
messages: Membrane
messages: Probable lipid hydrolase.

284591:YALI0 B03124g
gene id: 284591:YALI0_B03124g
uniprot id: Q6CFW1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

284591:YALI0 C03201g
gene id: 284591:YALI0_C03201g
uniprot id: Q6CD73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Mitochondrion inner membrane

284591:YALI0 C23056g
gene id: 284591:YALI0_C23056g
uniprot id: Q6CAZ9
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 B12716g
gene id: 284591:YALI0_B12716g
uniprot id: Q6CEV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

284591:YALI0 F06226g
gene id: 284591:YALI0_F06226g
uniprot id: Q6C2P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-22 family.
messages: Involved in peroxisome biogenesis.
messages: Membrane
messages: Peroxisome membrane

284591:YALI0 E03278g
gene id: 284591:YALI0_E03278g
uniprot id: Q6C770
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

284591:YALI0 C22660g
gene id: 284591:YALI0_C22660g
uniprot id: Q6CB15
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E12353g
gene id: 284591:YALI0_E12353g
uniprot id: Q6C653
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

284591:YALI0 E13552g
gene id: 284591:YALI0_E13552g
uniprot id: Q6C606
names: Similarity
messages: Belongs to the MUB1/samB family.

284591:YALI0 C18997g
gene id: 284591:YALI0_C18997g
uniprot id: Q6CBG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

284591:YALI0 F08437g
gene id: 284591:YALI0_F08437g
uniprot id: Q6C2F1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

284591:YALI0 F01210g
gene id: 284591:YALI0_F01210g
uniprot id: Q6C3A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

284591:YALI0 E06149g
gene id: 284591:YALI0_E06149g
uniprot id: Q6C6U5
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

284591:YALI0 E25850g
gene id: 284591:YALI0_E25850g
uniprot id: Q6C4L1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 B17138g
gene id: 284591:YALI0_B17138g
uniprot id: Q6CEA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 F06688g
gene id: 284591:YALI0_F06688g
uniprot id: Q6C2M1
names: Similarity
messages: Belongs to the UPF0047 family.

284591:YALI0 B15664g
gene id: 284591:YALI0_B15664g
uniprot id: Q6CEH1
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

284591:YALI0 E24057g
gene id: 284591:YALI0_E24057g
uniprot id: Q6C4S7
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

284591:YALI0 D26488g
gene id: 284591:YALI0_D26488g
uniprot id: Q6C7P3
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

284591:YALI0 C22682g
gene id: 284591:YALI0_C22682g
uniprot id: Q6CB14
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 C05170g
gene id: 284591:YALI0_C05170g
uniprot id: Q99145
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of the enzymatic activity (By similarity).
messages: Cytoplasm

284591:YALI0 B12188g
gene id: 284591:YALI0_B12188g
uniprot id: Q6CEX3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F14421g
gene id: 284591:YALI0_F14421g
uniprot id: Q6C1Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

284591:YALI0 C07304g
gene id: 284591:YALI0_C07304g
uniprot id: Q6CCR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

284591:YALI0 F21769g
gene id: 284591:YALI0_F21769g
uniprot id: Q6C0U1
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

284591:YALI0 C23320g
gene id: 284591:YALI0_C23320g
uniprot id: Q6CAY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284591:YALI0 C20075g
gene id: 284591:YALI0_C20075g
uniprot id: Q6CBC5
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

284591:YALI0 F26433g
gene id: 284591:YALI0_F26433g
uniprot id: Q6C0A5
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

284591:YALI0 D12100g
gene id: 284591:YALI0_D12100g
uniprot id: Q6C9D4
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B10065g
gene id: 284591:YALI0_B10065g
uniprot id: Q6CF59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

284591:YALI0 E13299g
gene id: 284591:YALI0_E13299g
uniprot id: Q6C616
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: Nucleus
messages: Required for pre-mRNA splicing.

284591:YALI0 A12023g
gene id: 284591:YALI0_A12023g
uniprot id: Q6CH63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cut8/STS1 family.
messages: Binds the proteasome.
messages: Cytoplasm
messages: Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
messages: Nucleus

284591:YALI0 E06853g
gene id: 284591:YALI0_E06853g
uniprot id: Q6C6R7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

284591:YALI0 B22990g
gene id: 284591:YALI0_B22990g
uniprot id: Q6CDL6
names: Similarity
messages: Belongs to the peptidase S8 family.

284591:YALI0 C08220g
gene id: 284591:YALI0_C08220g
uniprot id: Q6CCM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP2 family.
messages: Membrane

284591:YALI0 C03652g
gene id: 284591:YALI0_C03652g
uniprot id: Q6CD54
names: Similarity
messages: Belongs to the peptidase C48 family.

284591:YALI0 E14080g
gene id: 284591:YALI0_E14080g
uniprot id: Q6C5Y4
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 B01892g
gene id: 284591:YALI0_B01892g
uniprot id: Q6CG08
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

284591:YALI0 D16401g
gene id: 284591:YALI0_D16401g
uniprot id: Q6C8W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

284591:YALI0 C00363g
gene id: 284591:YALI0_C00363g
uniprot id: Q6CDI0
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 C16753g
gene id: 284591:YALI0_C16753g
uniprot id: Q6CBP5
names: Similarity
messages: Belongs to the group II decarboxylase family.

284591:YALI0 C07502g
gene id: 284591:YALI0_C07502g
uniprot id: Q6CCQ4
names: Similarity
messages: Belongs to the SLA2 family.

284591:YALI0 A03245g
gene id: 284591:YALI0_A03245g
uniprot id: Q6CHY9
names: Similarity
names: Subunit
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.
messages: Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.

284591:YALI0 F19404g
gene id: 284591:YALI0_F19404g
uniprot id: Q6C143
names: Subcellular Location Annotation
messages: Mitochondrion

284591:YALI0 C11539g
gene id: 284591:YALI0_C11539g
uniprot id: Q6CC85
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

284591:YALI0 B07381g
gene id: 284591:YALI0_B07381g
uniprot id: Q6CFF9
names: Function
names: Similarity
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.

284591:YALI0 D16797g
gene id: 284591:YALI0_D16797g
uniprot id: Q6C8V1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

284591:YALI0 B03036g
gene id: 284591:YALI0_B03036g
uniprot id: Q6CFW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284591:YALI0 E07491g
gene id: 284591:YALI0_E07491g
uniprot id: Q6C6P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

284591:YALI0 D09273g
gene id: 284591:YALI0_D09273g
uniprot id: Q6C9Q0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme c group covalently per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity).
messages: Mitochondrion intermembrane space

284591:YALI0 C18513g
gene id: 284591:YALI0_C18513g
uniprot id: Q6CBI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

284591:YALI0 D18194g
gene id: 284591:YALI0_D18194g
uniprot id: Q6C8N8
names: Similarity
messages: Belongs to the UFD1 family.

284591:YALI0 B15125g
gene id: 284591:YALI0_B15125g
uniprot id: Q6CEJ7
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

284591:YALI0 D11792g
gene id: 284591:YALI0_D11792g
uniprot id: Q6C9E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET5 subfamily.
messages: Cytoplasm
messages: Nucleus
messages: Putative protein lysine methyltransferase.

284591:YALI0 F17886g
gene id: 284591:YALI0_F17886g
uniprot id: Q6C1A6
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E18634g
gene id: 284591:YALI0_E18634g
uniprot id: Q6C5F0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

284591:YALI0 C09218g
gene id: 284591:YALI0_C09218g
uniprot id: Q6CCI0
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

284591:YALI0 D09163g
gene id: 284591:YALI0_D09163g
uniprot id: Q6C9Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNUT3 family.
messages: May play a role in mRNA splicing.
messages: Nucleus
messages: Part of a tri-snRNP complex.

284591:YALI0 C16929g
gene id: 284591:YALI0_C16929g
uniprot id: Q6CBN7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284591:YALI0 B13486g
gene id: 284591:YALI0_B13486g
uniprot id: Q6CES0
names: Similarity
messages: Belongs to the SRR1 family.

284591:YALI0 F04730g
gene id: 284591:YALI0_F04730g
uniprot id: Q8TFK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small GTPase superfamily. Ran family.
messages: Found in a nuclear export complex with RanGTP, exportin and pre-miRNA (By similarity).
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity).
messages: Nucleus

284591:YALI0 C22341g
gene id: 284591:YALI0_C22341g
uniprot id: Q6CB30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTC5 family.
messages: Cytoplasm
messages: May be involved in a process influencing telomere capping.

284591:YALI0 F15279g
gene id: 284591:YALI0_F15279g
uniprot id: Q6C1L1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

284591:YALI0 F04400g
gene id: 284591:YALI0_F04400g
uniprot id: Q6C2X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 F20174g
gene id: 284591:YALI0_F20174g
uniprot id: Q6C111
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E18832g
gene id: 284591:YALI0_E18832g
uniprot id: Q6C5E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

284591:YALI0 B21340g
gene id: 284591:YALI0_B21340g
uniprot id: Q6CDT5
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

284591:YALI0 C10135g
gene id: 284591:YALI0_C10135g
uniprot id: B5FVC3
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 C23639g
gene id: 284591:YALI0_C23639g
uniprot id: Q6CAX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
messages: Nucleus

284591:YALI0 F31845g
gene id: 284591:YALI0_F31845g
uniprot id: Q6BZQ2
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B19800g
gene id: 284591:YALI0_B19800g
uniprot id: Q6CE01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

284591:YALI0 A02453g
gene id: 284591:YALI0_A02453g
uniprot id: Q6CI19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family.
messages: Cell membrane
messages: Vacuole membrane

284591:YALI0 E01628g
gene id: 284591:YALI0_E01628g
uniprot id: Q6C7D8
names: Subcellular Location Annotation
messages: nucleolus

284591:YALI0 D25256g
gene id: 284591:YALI0_D25256g
uniprot id: Q6C7U5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

284591:YALI0 C22066g
gene id: 284591:YALI0_C22066g
uniprot id: Q6CB43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: nuclear pore complex

284591:YALI0 A20086g
gene id: 284591:YALI0_A20086g
uniprot id: Q6CGE1
names: Function
names: Similarity
messages: Belongs to the AB hydrolase superfamily.
messages: Demethylates proteins that have been reversibly carboxymethylated. Demethylates the phosphatase PP2A catalytic subunit (By similarity).

284591:YALI0 A02541g
gene id: 284591:YALI0_A02541g
uniprot id: Q6CI15
names: Function
names: Similarity
messages: Catalyzes three sequential steps of tetrahydrofolate biosynthesis.
messages: In the C-terminal section; belongs to the DHPS family.
messages: In the N-terminal section; belongs to the DHNA family.
messages: In the central section; belongs to the HPPK family.

284591:YALI0 D04983g
gene id: 284591:YALI0_D04983g
uniprot id: Q6CA86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Mitochondrion outer membrane
messages: Monomer. Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.
messages: NADH-dependent reductase for DPH3 and cytochrome b5. Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1. By reducing DPH3, also involved in the formation of the tRNA wobble base modification mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), mediated by the elongator complex. The cytochrome b5/NADH cytochrome b5 reductase electron transfer system supports the catalytic activity of several sterol biosynthetic enzymes.

284591:YALI0 E16258g
gene id: 284591:YALI0_E16258g
uniprot id: Q6C5P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Clp1 family. NOL9/GRC3 subfamily.
messages: Polynucleotide 5'-kinase involved in rRNA processing.
messages: nucleolus

284591:YALI0 D09361g
gene id: 284591:YALI0_D09361g
uniprot id: Q6C9P6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

284591:YALI0 D21846g
gene id: 284591:YALI0_D21846g
uniprot id: Q6CHG3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

284591:YALI0 C22594g
gene id: 284591:YALI0_C22594g
uniprot id: Q6CB18
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F02783g
gene id: 284591:YALI0_F02783g
uniprot id: Q6C343
names: Similarity
messages: Belongs to the NPR2 family.

284591:YALI0 A07018g
gene id: 284591:YALI0_A07018g
uniprot id: Q6CHN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLA1 family.
messages: Cell membrane
messages: Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
messages: Component of the PAN1 actin cytoskeleton-regulatory complex.
messages: Endosome membrane
messages: actin patch

284591:YALI0 B10538g
gene id: 284591:YALI0_B10538g
uniprot id: Q6CF37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus

284591:YALI0 E01826g
gene id: 284591:YALI0_E01826g
uniprot id: Q6C7D0
names: Function
names: Subcellular Location Annotation
messages: Acts as component of the general transcription and DNA repair factor IIH (TFIIH or factor B), which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. TFIIH as CTD kinase activity and DNA-dependent ATPase activity, and is essential for polymerase II transcription (By similarity).
messages: Nucleus

284591:YALI0 D24970g
gene id: 284591:YALI0_D24970g
uniprot id: Q6C7V8
names: Similarity
messages: Belongs to the MYG1 family.

284591:YALI0 B22924g
gene id: 284591:YALI0_B22924g
uniprot id: Q6CDL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

284591:YALI0 F24453g
gene id: 284591:YALI0_F24453g
uniprot id: Q6C0I2
names: Similarity
messages: Belongs to the peptidase S8 family.

284591:YALI0 F19734g
gene id: 284591:YALI0_F19734g
uniprot id: Q6C128
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F13937g
gene id: 284591:YALI0_F13937g
uniprot id: Q6C1S2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284591:YALI0 B16896g
gene id: 284591:YALI0_B16896g
uniprot id: Q6CEB8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in ribosome assembly.
messages: Associates with pre-ribosomal particles.
messages: Belongs to the DEAD box helicase family. DDX27/DRS1 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284591:YALI0 E28270g
gene id: 284591:YALI0_E28270g
uniprot id: Q6C4B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 A19426g
gene id: 284591:YALI0_A19426g
uniprot id: Q6CGH1
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

284591:YALI0 A06699g
gene id: 284591:YALI0_A06699g
uniprot id: Q6CHP5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: G proteins are composed of 3 units, alpha, beta and gamma.
messages: Membrane

284591:YALI0 F16379g
gene id: 284591:YALI0_F16379g
uniprot id: Q6C1G8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

284591:YALI0 C12232g
gene id: 284591:YALI0_C12232g
uniprot id: Q6CC59
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B05390g
gene id: 284591:YALI0_B05390g
uniprot id: Q6CFN5
names: Similarity
messages: Belongs to the RMD1/sif2 family.

284591:YALI0 B11022g
gene id: 284591:YALI0_B11022g
uniprot id: Q6CF19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

284591:YALI0 D21626g
gene id: 284591:YALI0_D21626g
uniprot id: Q6C892
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

284591:YALI0 F25685g
gene id: 284591:YALI0_F25685g
uniprot id: Q6C0D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69.2) family.
messages: Involved in cellular auxin homeostasis by regulating auxin metabolism. Regulates intracellular auxin accumulation at the endoplasmic reticulum and thus auxin availability for nuclear auxin signaling.
messages: Membrane

284591:YALI0 E24409g
gene id: 284591:YALI0_E24409g
uniprot id: Q6C4R1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC4 family.
messages: Mitochondrion intermembrane space
messages: The twin Cx9C motifs are involved in the recognition by the mitochondrial disulfide relay system.

284591:YALI0 E30899g
gene id: 284591:YALI0_E30899g
uniprot id: Q6C402
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-Z subfamily.
messages: Cytoplasm

284591:YALI0 A19536g
gene id: 284591:YALI0_A19536g
uniprot id: Q6CGG6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284591:YALI0 F09295g
gene id: 284591:YALI0_F09295g
uniprot id: Q6C2B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

284591:YALI0 F30217g
gene id: 284591:YALI0_F30217g
uniprot id: Q6BZX2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

284591:YALI0 C10670g
gene id: 284591:YALI0_C10670g
uniprot id: Q6CCC4
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E23408g
gene id: 284591:YALI0_E23408g
uniprot id: Q6C4V4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS11 family.
messages: Component of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex. Component of the class C core vacuole/endosome tethering (CORVET) complex.
messages: Vacuole membrane

284591:YALI0 D26213g
gene id: 284591:YALI0_D26213g
uniprot id: Q6C7Q7
names: Similarity
messages: Belongs to the protein kinase superfamily.

284591:YALI0 D03465g
gene id: 284591:YALI0_D03465g
uniprot id: P30887
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Probably serves to scavenge phosphorus for growing cells.
messages: Secreted

284591:YALI0 E33627g
gene id: 284591:YALI0_E33627g
uniprot id: Q7Z8R5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the palI/RIM9 family.
messages: Cell membrane
messages: It is uncertain whether Met-1 or Met-5 is the initiator.
messages: Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.

284591:YALI0 B01078g
gene id: 284591:YALI0_B01078g
uniprot id: Q6CG40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

284591:YALI0 D15246g
gene id: 284591:YALI0_D15246g
uniprot id: Q6C910
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

284591:YALI0 D06193g
gene id: 284591:YALI0_D06193g
uniprot id: Q6CA38
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E32736g
gene id: 284591:YALI0_E32736g
uniprot id: B5FVG6
names: Function
messages: Cleaves A-5'-PPP-5'A to yield AMP and ADP. Can cleave all dinucleoside polyphosphates, provided the phosphate chain contains at least 3 phosphates and that 1 of the 2 bases composing the nucleotide is a purine. Is most effective on dinucleoside triphosphates. Negatively regulates intracellular dinucleoside polyphosphate levels, which elevate following heat shock.

284591:YALI0 F21406g
gene id: 284591:YALI0_F21406g
uniprot id: Q6C0V4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

284591:YALI0 E10175g
gene id: 284591:YALI0_E10175g
uniprot id: Q6C6E4
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 B02544g
gene id: 284591:YALI0_B02544g
uniprot id: Q6CFY4
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D12584g
gene id: 284591:YALI0_D12584g
uniprot id: Q6C9B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: F-type ATP synthases have 2 components, the catalytic core F(1) and the membrane-embedded component F(0), linked together by a central stalk and a peripheral stalk (PubMed:27373333). The central stalk, also called rotor shaft, is often seen as part of F(1) (PubMed:27373333). The peripheral stalk is seen as part of F(0) (PubMed:27373333). F(0) contains the membrane channel next to the rotor (PubMed:27373333). F-type ATP synthases form dimers but each monomer functions independently in ATP generation (PubMed:27373333). The dimer consists of 17 different polypeptides: ATP1 (subunit alpha, 3 molecules per monomer, part of F(1)), ATP2 (subunit beta, 3 copies per monomer, part of F(1)), ATP3 (subunit gamma, part of the central stalk), ATP4 (subunit b, part of the peripheral stalk), ATP5/OSCP (subunit 5/OSCP, part of the peripheral stalk), ATP6 (subunit a, part of the peripheral stalk), ATP7 (subunit d, part of the peripheral stalk), ATP8 (subunit 8, part of the peripheral stalk), OLI1 (subunit c, part of the rotor, 10 molecules per monomer), ATP14 (subunit h, part of the peripheral stalk), ATP15 (subunit epsilon, part of the central stalk), ATP16 (subunit delta, part of the central stalk), ATP17 (subunit f, part of the peripheral stalk), ATP18 (subunit i/j, part of the peripheral stalk), ATP19 (subunit k, dimer-specific, at interface between monomers), ATP20 (subunit g, at interface between monomers), TIM11 (subunit e, at interface between monomers) (PubMed:27373333, PubMed:25759169).
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169). F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27373333). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (PubMed:27373333). Part of the complex F(0) domain and the peripheral stalk, which acts as a stator to hold the catalytic alpha/ATP1(3)beta/ATP2(3) subcomplex and subunit a/ATP6 static relative to the rotary elements (PubMed:27373333).
messages: Mitochondrion inner membrane

284591:YALI0 E25740g
gene id: 284591:YALI0_E25740g
uniprot id: Q6C4L7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

284591:YALI0 E12023g
gene id: 284591:YALI0_E12023g
uniprot id: Q6C668
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ECO subfamily.
messages: Nucleus
messages: Probable acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by acetylating the cohesin complex component SMC3 (By similarity).

284591:YALI0 E35200g
gene id: 284591:YALI0_E35200g
uniprot id: Q6C3G0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F23485g
gene id: 284591:YALI0_F23485g
uniprot id: Q6C0M2
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E12199g
gene id: 284591:YALI0_E12199g
uniprot id: Q6C659
names: Similarity
messages: Belongs to the glycosyltransferase 34 family.

284591:YALI0 D09911g
gene id: 284591:YALI0_D09911g
uniprot id: Q6C9M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWC4 family.
messages: Component of the SWR1 chromatin-remodeling complex and of the NuA4 histone acetyltransferase complex.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
messages: Nucleus

284591:YALI0 C09141g
gene id: 284591:YALI0_C09141g
uniprot id: O59949
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

284591:YALI0 C10252g
gene id: 284591:YALI0_C10252g
uniprot id: Q6CCD8
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

284591:YALI0 E13464g
gene id: 284591:YALI0_E13464g
uniprot id: Q6C610
names: Similarity
messages: Belongs to the peptidase M24B family.

284591:YALI0 C12771g
gene id: 284591:YALI0_C12771g
uniprot id: Q6CC38
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

284591:YALI0 C09680g
gene id: 284591:YALI0_C09680g
uniprot id: Q6CCG0
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

284591:YALI0 A10813g
gene id: 284591:YALI0_A10813g
uniprot id: Q6CHA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Mitochondrion
messages: Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria (By similarity).

284591:YALI0 D11132g
gene id: 284591:YALI0_D11132g
uniprot id: Q6C9H6
names: Subcellular Location Annotation
messages: Cytoplasm

284591:YALI0 C22946g
gene id: 284591:YALI0_C22946g
uniprot id: Q6CB03
names: Similarity
messages: Belongs to the VPS8 family.

284591:YALI0 C10989g
gene id: 284591:YALI0_C10989g
uniprot id: Q6CCA9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

284591:YALI0 F07623g
gene id: 284591:YALI0_F07623g
uniprot id: Q6C2I5
names: Similarity
messages: Belongs to the FPG family.

284591:YALI0 F05522g
gene id: 284591:YALI0_F05522g
uniprot id: Q6C2S6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

284591:YALI0 A14454g
gene id: 284591:YALI0_A14454g
uniprot id: Q6CH05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 C12881g
gene id: 284591:YALI0_C12881g
uniprot id: Q6CC35
names: Similarity
messages: Belongs to the RRP15 family.

284591:YALI0 A09933g
gene id: 284591:YALI0_A09933g
uniprot id: B5RSK0
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL41 family.
messages: Component of the large ribosomal subunit.

284591:YALI0 F06468g
gene id: 284591:YALI0_F06468g
uniprot id: Q6C2N1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

284591:YALI0 C06754g
gene id: 284591:YALI0_C06754g
uniprot id: Q6CCT3
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

284591:YALI0 F22803g
gene id: 284591:YALI0_F22803g
uniprot id: Q6C0P6
names: Similarity
messages: Belongs to the ZPR1 family.

284591:YALI0 C18821g
gene id: 284591:YALI0_C18821g
uniprot id: Q6CBH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASP family.
messages: Golgi apparatus membrane
messages: Membrane

284591:YALI0 B18238g
gene id: 284591:YALI0_B18238g
uniprot id: Q6CE64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

284591:YALI0 C09328g
gene id: 284591:YALI0_C09328g
uniprot id: Q6CCH5
names: Similarity
messages: Belongs to the SGT family.

284591:YALI0 A11157g
gene id: 284591:YALI0_A11157g
uniprot id: Q6CH90
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 also plays a role in pre-mRNA splicing and spliceosome assembly. May be involved in rDNA and telomeric silencing, and maintenance of genome integrity (By similarity).
messages: Belongs to the DEAD box helicase family. DECD subfamily.
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284591:YALI0 D01309g
gene id: 284591:YALI0_D01309g
uniprot id: Q6CAN2
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

284591:YALI0 C03982g
gene id: 284591:YALI0_C03982g
uniprot id: Q6CD42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Nucleus
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.

284591:YALI0 B05236g
gene id: 284591:YALI0_B05236g
uniprot id: Q6CFP1
names: Similarity
messages: Belongs to the SLX4 family.

284591:YALI0 E29535g
gene id: 284591:YALI0_E29535g
uniprot id: Q6C456
names: Function
names: Subcellular Location Annotation
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus

284591:YALI0 B02068g
gene id: 284591:YALI0_B02068g
uniprot id: Q6CG02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284591:YALI0 B12782g
gene id: 284591:YALI0_B12782g
uniprot id: Q6CEU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIP5 family.
messages: Cytoplasm
messages: May negatively regulate the SNF1 kinase.

284591:YALI0 F14597g
gene id: 284591:YALI0_F14597g
uniprot id: Q6C1P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

284591:YALI0 D25696g
gene id: 284591:YALI0_D25696g
uniprot id: Q6C7S7
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 C16995g
gene id: 284591:YALI0_C16995g
uniprot id: Q6CBN4
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

284591:YALI0 C18381g
gene id: 284591:YALI0_C18381g
uniprot id: Q6CBI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Cytoplasm
messages: Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.
messages: Interacts with NAR1.
messages: Nucleus

284591:YALI0 D01265g
gene id: 284591:YALI0_D01265g
uniprot id: Q6CAN4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

284591:YALI0 D18458g
gene id: 284591:YALI0_D18458g
uniprot id: Q6C8M5
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

284591:YALI0 D00583g
gene id: 284591:YALI0_D00583g
uniprot id: Q6CAR5
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

284591:YALI0 B01166g
gene id: 284591:YALI0_B01166g
uniprot id: Q6CG37
names: Function
messages: F-box protein probably involved in ubiquitin conjugation pathway.

284591:YALI0 A05423g
gene id: 284591:YALI0_A05423g
uniprot id: Q6CHS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

284591:YALI0 B03498g
gene id: 284591:YALI0_B03498g
uniprot id: Q6CFV0
names: Similarity
messages: Belongs to the MT-A70-like family.

284591:YALI0 F08481g
gene id: 284591:YALI0_F08481g
uniprot id: Q9HFC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Heterotrimeric complex composed of SEC61, SEB1 and SSS1.
messages: Necessary for protein translocation in the endoplasmic reticulum.

284591:YALI0 D03619g
gene id: 284591:YALI0_D03619g
uniprot id: Q6CAE1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284591:YALI0 D07282g
gene id: 284591:YALI0_D07282g
uniprot id: Q6C9Y8
names: Similarity
messages: Belongs to the multicopper oxidase family.

284591:YALI0 C10010g
gene id: 284591:YALI0_C10010g
uniprot id: Q6CCE7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284591:YALI0 D09625g
gene id: 284591:YALI0_D09625g
uniprot id: Q6C9N9
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 C08547g
gene id: 284591:YALI0_C08547g
uniprot id: Q6CCK9
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 B14927g
gene id: 284591:YALI0_B14927g
uniprot id: Q6CEK6
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

284591:YALI0 D08624g
gene id: 284591:YALI0_D08624g
uniprot id: Q6C9T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284591:YALI0 B17402g
gene id: 284591:YALI0_B17402g
uniprot id: Q6CE97
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

284591:YALI0 A16863g
gene id: 284591:YALI0_A16863g
uniprot id: Q6CGR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 F28391g
gene id: 284591:YALI0_F28391g
uniprot id: Q6C024
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).
messages: Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.
messages: Component of the U5 snRNP complex.
messages: Cytoplasm
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284591:YALI0 A02695g
gene id: 284591:YALI0_A02695g
uniprot id: Q6CI08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

284591:YALI0 D26972g
gene id: 284591:YALI0_D26972g
uniprot id: Q6C7M1
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

284591:YALI0 F21505g
gene id: 284591:YALI0_F21505g
uniprot id: P41922
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Fungal signal recognition particle consists of a 7S RNA molecule (scR1) and at least six protein subunits: SRP72, SRP68, SRP54, SEC65, SRP21 and SRP14.
messages: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. It must be involved intimately in the translocation of a wide variety of protein substrates (By similarity).

284591:YALI0 E00418g
gene id: 284591:YALI0_E00418g
uniprot id: Q6C7J1
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

284591:YALI0 B00792g
gene id: 284591:YALI0_B00792g
uniprot id: Q6CG53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Complex I is composed of 42 different subunits.
messages: Mitochondrion inner membrane

284591:YALI0 F21791g
gene id: 284591:YALI0_F21791g
uniprot id: Q6C0U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TPT transporter family. SLC35D subfamily.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homooligomer.
messages: Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.

284591:YALI0 A03553g
gene id: 284591:YALI0_A03553g
uniprot id: Q6CHY3
names: Function
names: Similarity
messages: Belongs to the VPS16 family.
messages: Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.

284591:YALI0 A08668g
gene id: 284591:YALI0_A08668g
uniprot id: Q6CHH8
names: Similarity
messages: Belongs to the pyridoxine kinase family.

284591:YALI0 B03630g
gene id: 284591:YALI0_B03630g
uniprot id: Q6CFU6
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

284591:YALI0 F00924g
gene id: 284591:YALI0_F00924g
uniprot id: F2Z619
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

284591:YALI0 E15466g
gene id: 284591:YALI0_E15466g
uniprot id: Q6C5T0
names: Similarity
messages: Belongs to the TSR2 family.

284591:YALI0 E29865g
gene id: 284591:YALI0_E29865g
uniprot id: Q6C443
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXR1 family.
messages: May be involved in protection from oxidative damage.
messages: Mitochondrion

284591:YALI0 D22022g
gene id: 284591:YALI0_D22022g
uniprot id: Q6C877
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATP synthases have 2 components, the catalytic core F(1) and the membrane-embedded component F(0), linked together by a central stalk and a peripheral stalk (PubMed:27373333). The central stalk, also called rotor shaft, is often seen as part of F(1) (PubMed:27373333). The peripheral stalk is seen as part of F(0) (PubMed:27373333). F(0) contains the membrane channel next to the rotor (PubMed:27373333). F-type ATP synthases form dimers but each monomer functions independently in ATP generation (PubMed:27373333). The dimer consists of 17 different polypeptides: ATP1 (subunit alpha, 3 molecules per monomer, part of F(1)), ATP2 (subunit beta, 3 copies per monomer, part of F(1)), ATP3 (subunit gamma, part of the central stalk), ATP4 (subunit b, part of the peripheral stalk), ATP5/OSCP (subunit 5/OSCP, part of the peripheral stalk), ATP6 (subunit a, part of the peripheral stalk), ATP7 (subunit d, part of the peripheral stalk), ATP8 (subunit 8, part of the peripheral stalk), OLI1 (subunit c, part of the rotor, 10 molecules per monomer), ATP14 (subunit h, part of the peripheral stalk), ATP15 (subunit epsilon, part of the central stalk), ATP16 (subunit delta, part of the central stalk), ATP17 (subunit f, part of the peripheral stalk), ATP18 (subunit i/j, part of the peripheral stalk), ATP19 (subunit k, dimer-specific, at interface between monomers), ATP20 (subunit g, at interface between monomers), TIM11 (subunit e, at interface between monomers) (PubMed:27373333, PubMed:25759169).
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169). F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27373333). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (PubMed:27373333). Part of the complex F(1) domain and the central stalk which is part of the complex rotary element (PubMed:27373333). Rotation of the central stalk against the surrounding alpha/ATP1(3)beta/ATP2(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta/ATP2 subunits (PubMed:27373333).
messages: Mitochondrion inner membrane

284591:YALI0 C08943g
gene id: 284591:YALI0_C08943g
uniprot id: Q6CCJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 F18942g
gene id: 284591:YALI0_F18942g
uniprot id: Q6C161
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

284591:YALI0 D14344g
gene id: 284591:YALI0_D14344g
uniprot id: Q6C945
names: Similarity
messages: Belongs to the GET4 family.

284591:YALI0 D25674g
gene id: 284591:YALI0_D25674g
uniprot id: Q6C7S8
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 B13420g
gene id: 284591:YALI0_B13420g
uniprot id: Q6CES3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

284591:YALI0 B13156g
gene id: 284591:YALI0_B13156g
uniprot id: Q6CET3
names: Similarity
messages: Belongs to the calreticulin family.

284591:YALI0 F30745g
gene id: 284591:YALI0_F30745g
uniprot id: Q6BZU8
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

284591:YALI0 D22594g
gene id: 284591:YALI0_D22594g
uniprot id: Q6C854
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Membrane

284591:YALI0 B20988g
gene id: 284591:YALI0_B20988g
uniprot id: Q6CDV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gemin-2 family.
messages: Cytoplasm

284591:YALI0 F16313g
gene id: 284591:YALI0_F16313g
uniprot id: Q6C1H1
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 D06974g
gene id: 284591:YALI0_D06974g
uniprot id: Q6CA02
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

284591:YALI0 C06842g
gene id: 284591:YALI0_C06842g
uniprot id: Q6CCS9
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 D20768g
gene id: 284591:YALI0_D20768g
uniprot id: Q6C8C6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

284591:YALI0 C06952g
gene id: 284591:YALI0_C06952g
uniprot id: Q6CCS4
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

284591:YALI0 D17952g
gene id: 284591:YALI0_D17952g
uniprot id: Q6C8Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 D02145g
gene id: 284591:YALI0_D02145g
uniprot id: Q6CAJ8
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

284591:YALI0 C20999g
gene id: 284591:YALI0_C20999g
uniprot id: Q6CB92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

284591:YALI0 E25025g
gene id: 284591:YALI0_E25025g
uniprot id: Q6C4N4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL19 family.

284591:YALI0 A12067g
gene id: 284591:YALI0_A12067g
uniprot id: Q6CH61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

284591:YALI0 D07326g
gene id: 284591:YALI0_D07326g
uniprot id: Q6C9Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrion

284591:YALI0 E29293g
gene id: 284591:YALI0_E29293g
uniprot id: Q6C468
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NCBP2 family.
messages: Nucleus

284591:YALI0 E28006g
gene id: 284591:YALI0_E28006g
uniprot id: Q6C4C0
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 F27577g
gene id: 284591:YALI0_F27577g
uniprot id: Q6C059
names: Similarity
messages: Belongs to the synembryn family.

284591:YALI0 B21560g
gene id: 284591:YALI0_B21560g
uniprot id: Q6CDS5
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E21175g
gene id: 284591:YALI0_E21175g
uniprot id: Q6C542
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YME2 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape. Involved in the regulation of mtDNA nucleotide structure and number. May have a dispensable role in early maturation of pre-rRNA.

284591:YALI0 F16577g
gene id: 284591:YALI0_F16577g
uniprot id: Q6C1G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFH5 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Microsome membrane
messages: Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane.

284591:YALI0 C02915g
gene id: 284591:YALI0_C02915g
uniprot id: Q6CD84
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 B13684g
gene id: 284591:YALI0_B13684g
uniprot id: Q6CER3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DASH complex DAD1 family.
messages: Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
messages: Nucleus
messages: The DASH complex oligomerizes to form rings that encircle the microtubules.
messages: kinetochore
messages: spindle

284591:YALI0 D15312g
gene id: 284591:YALI0_D15312g
uniprot id: Q6C907
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284591:YALI0 D07986g
gene id: 284591:YALI0_D07986g
uniprot id: Q6C9V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Sterol O-acyltransferase that catalyzes the formation of stery esters.

284591:YALI0 E10285g
gene id: 284591:YALI0_E10285g
uniprot id: Q6C6D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the misato family.
messages: Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.
messages: Mitochondrion

284591:YALI0 F03795g
gene id: 284591:YALI0_F03795g
uniprot id: Q6C2Z8
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D19624g
gene id: 284591:YALI0_D19624g
uniprot id: Q6C8H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LOC1 family.
messages: Component of the 66S pre-ribosomal particle.
messages: Required for efficient assembly and nuclear export of the 60S ribosomal subunit.
messages: nucleolus

284591:YALI0 D06886g
gene id: 284591:YALI0_D06886g
uniprot id: Q6CA06
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MMM1 family.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
messages: Endoplasmic reticulum membrane
messages: Homodimer. Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.
messages: The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.

284591:YALI0 E19074g
gene id: 284591:YALI0_E19074g
uniprot id: Q6C5D0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NBP35 and two labile, bridging clusters between subunits of the NBP35-CFD1 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export.
messages: Cytoplasm
messages: Heterotetramer of 2 NBP35 and 2 CFD1 chains.

284591:YALI0 D01628g
gene id: 284591:YALI0_D01628g
uniprot id: Q6CAL7
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

284591:YALI0 C16951g
gene id: 284591:YALI0_C16951g
uniprot id: Q6CBN6
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284591:YALI0 A09317g
gene id: 284591:YALI0_A09317g
uniprot id: Q6CHG3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

284591:YALI0 A10879g
gene id: 284591:YALI0_A10879g
uniprot id: Q6CHA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.

284591:YALI0 F20790g
gene id: 284591:YALI0_F20790g
uniprot id: Q6C0Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

284591:YALI0 C04433g
gene id: 284591:YALI0_C04433g
uniprot id: Q6CD21
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

284591:YALI0 F17622g
gene id: 284591:YALI0_F17622g
uniprot id: Q6C1B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.
messages: nucleolus

284591:YALI0 B10758g
gene id: 284591:YALI0_B10758g
uniprot id: Q6CF29
names: Similarity
messages: Belongs to the protein kinase superfamily.

284591:YALI0 F07821g
gene id: 284591:YALI0_F07821g
uniprot id: Q6C2H6
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

284591:YALI0 E27269g
gene id: 284591:YALI0_E27269g
uniprot id: Q6C4F2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

284591:YALI0 A05181g
gene id: 284591:YALI0_A05181g
uniprot id: Q6CHT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: May play a role in ribosome biogenesis.
messages: nucleolus
messages: nucleoplasm

284591:YALI0 C18227g
gene id: 284591:YALI0_C18227g
uniprot id: Q6CBJ5
names: Similarity
messages: Belongs to the CBP3 family.

284591:YALI0 C14256g
gene id: 284591:YALI0_C14256g
uniprot id: Q6CBZ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Cytoplasm
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PAB1 (via PABC domain), conferring substrate specificity of the enzyme complex.
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

284591:YALI0 C01573g
gene id: 284591:YALI0_C01573g
uniprot id: Q6CDC9
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E04829g
gene id: 284591:YALI0_E04829g
uniprot id: Q6C703
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.
messages: Component of the COP9 signalosome (CSN) complex.
messages: Cytoplasm
messages: Nucleus
messages: The JAMM motif is essential for the protease activity of the CSN complex resulting in deneddylation of cullins. It constitutes the catalytic center of the complex (By similarity).

284591:YALI0 E21472g
gene id: 284591:YALI0_E21472g
uniprot id: B5FVI1
names: Similarity
messages: Belongs to the thioesterase PaaI family.

284591:YALI0 E30327g
gene id: 284591:YALI0_E30327g
uniprot id: Q6C426
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E14663g
gene id: 284591:YALI0_E14663g
uniprot id: Q6C5W2
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 D15026g
gene id: 284591:YALI0_D15026g
uniprot id: Q6C920
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F13013g
gene id: 284591:YALI0_F13013g
uniprot id: Q6C1V8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

284591:YALI0 A16610g
gene id: 284591:YALI0_A16610g
uniprot id: Q6CGS5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Converts sphingomyelin to ceramide.

284591:YALI0 E09064g
gene id: 284591:YALI0_E09064g
uniprot id: Q6C6J3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F01078g
gene id: 284591:YALI0_F01078g
uniprot id: Q6C3B4
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E23738g
gene id: 284591:YALI0_E23738g
uniprot id: Q6C4T9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

284591:YALI0 E34852g
gene id: 284591:YALI0_E34852g
uniprot id: Q6C3H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

284591:YALI0 E20933g
gene id: 284591:YALI0_E20933g
uniprot id: Q6C553
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

284591:YALI0 F07337g
gene id: 284591:YALI0_F07337g
uniprot id: Q6C2J6
names: Similarity
messages: Belongs to the activator 1 small subunits family.

284591:YALI0 D20240g
gene id: 284591:YALI0_D20240g
uniprot id: Q6C8E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

284591:YALI0 D10285g
gene id: 284591:YALI0_D10285g
uniprot id: Q6C9L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

284591:YALI0 D26906g
gene id: 284591:YALI0_D26906g
uniprot id: Q6C7M4
names: Subcellular Location Annotation
messages: Vacuole

284591:YALI0 E19481g
gene id: 284591:YALI0_E19481g
uniprot id: B5FVI0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.
messages: Cytoplasm

284591:YALI0 E20053g
gene id: 284591:YALI0_E20053g
uniprot id: Q6C590
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

284591:YALI0 E32505g
gene id: 284591:YALI0_E32505g
uniprot id: Q6C3S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

284591:YALI0 E04246g
gene id: 284591:YALI0_E04246g
uniprot id: Q6C730
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.

284591:YALI0 E17853g
gene id: 284591:YALI0_E17853g
uniprot id: Q6C5I2
names: Subcellular Location Annotation
messages: Cytoplasm

284591:YALI0 E02046g
gene id: 284591:YALI0_E02046g
uniprot id: Q6C7C0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Phosphorylation of the TEDS site (Ser-358) is required for the polarization of the actin cytoskeleton. Phosphorylation probably activates the myosin-I ATPase activity (By similarity).
messages: The myosin motor domain displays actin-stimulated ATPase activity and generates a mechanochemical force.
messages: The tail domain participates in molecular interactions that specify the role of the motor domain (By similarity). It is composed of several tail homology (TH) domains, namely a putative phospholipid-binding myosin tail domain (also named TH1), an Ala- and Pro-rich domain (TH2), followed by an SH3 domain and a C-terminal acidic domain (TH3).
messages: Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex (By similarity).
messages: actin patch

284591:YALI0 B15103g
gene id: 284591:YALI0_B15103g
uniprot id: Q6CEJ8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.

284591:YALI0 E01848g
gene id: 284591:YALI0_E01848g
uniprot id: Q6C7C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CGI121/TPRKB family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. CGI121 is not required for tRNA modification (By similarity).
messages: Nucleus
messages: telomere

284591:YALI0 E28787g
gene id: 284591:YALI0_E28787g
uniprot id: Q6C490
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

284591:YALI0 D27324g
gene id: 284591:YALI0_D27324g
uniprot id: Q6C7K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: Cytoplasm
messages: Involved in nuclear export, actin cytoskeleton organization and vesicular transport.
messages: Nucleus

284591:YALI0 F26103g
gene id: 284591:YALI0_F26103g
uniprot id: Q6C0B8
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

284591:YALI0 D14454g
gene id: 284591:YALI0_D14454g
uniprot id: Q6C940
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E11033g
gene id: 284591:YALI0_E11033g
uniprot id: Q6C6A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

284591:YALI0 B04312g
gene id: 284591:YALI0_B04312g
uniprot id: Q6CFS3
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

284591:YALI0 B10736g
gene id: 284591:YALI0_B10736g
uniprot id: Q6CF30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284591:YALI0 E06017g
gene id: 284591:YALI0_E06017g
uniprot id: Q6C6V1
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

284591:YALI0 E02244g
gene id: 284591:YALI0_E02244g
uniprot id: Q6C7B1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

284591:YALI0 C17941g
gene id: 284591:YALI0_C17941g
uniprot id: Q6CBK6
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

284591:YALI0 F30305g
gene id: 284591:YALI0_F30305g
uniprot id: Q6BZW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

284591:YALI0 B01804g
gene id: 284591:YALI0_B01804g
uniprot id: Q6CG12
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F03454g
gene id: 284591:YALI0_F03454g
uniprot id: Q6C314
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

284591:YALI0 C06369g
gene id: 284591:YALI0_C06369g
uniprot id: Q6CCU7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

284591:YALI0 F22781g
gene id: 284591:YALI0_F22781g
uniprot id: Q6C0P7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.

284591:YALI0 E24123g
gene id: 284591:YALI0_E24123g
uniprot id: Q6C4S4
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B23408g
gene id: 284591:YALI0_B23408g
uniprot id: Q6CDJ7
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

284591:YALI0 C00187g
gene id: 284591:YALI0_C00187g
uniprot id: Q6CDI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PC-esterase family. CASD1 subfamily.
messages: Membrane

284591:YALI0 D01485g
gene id: 284591:YALI0_D01485g
uniprot id: Q6CAM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.

284591:YALI0 E07205g
gene id: 284591:YALI0_E07205g
uniprot id: Q6C6Q5
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F11627g
gene id: 284591:YALI0_F11627g
uniprot id: Q6C217
names: Cofactor
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.

284591:YALI0 F03927g
gene id: 284591:YALI0_F03927g
uniprot id: Q6C2Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.

284591:YALI0 E31669g
gene id: 284591:YALI0_E31669g
uniprot id: Q6C3W4
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 F07106g
gene id: 284591:YALI0_F07106g
uniprot id: Q6C2K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

284591:YALI0 E24761g
gene id: 284591:YALI0_E24761g
uniprot id: Q6C4P5
names: Similarity
messages: Belongs to the TRM112 family.

284591:YALI0 E19514g
gene id: 284591:YALI0_E19514g
uniprot id: Q6C5B3
names: Similarity
messages: Belongs to the PAT1 family.

284591:YALI0 B03575g
gene id: 284591:YALI0_B03575g
uniprot id: B5FVB0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284591:YALI0 A04961g
gene id: 284591:YALI0_A04961g
uniprot id: Q6CHU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

284591:YALI0 C17281g
gene id: 284591:YALI0_C17281g
uniprot id: Q6CBM5
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E14256g
gene id: 284591:YALI0_E14256g
uniprot id: Q6C5X6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284591:YALI0 A17985g
gene id: 284591:YALI0_A17985g
uniprot id: Q6CGM8
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B14146g
gene id: 284591:YALI0_B14146g
uniprot id: Q6CEP2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uL10 forms part of the P stalk that participates in recruiting G proteins to the ribosome.

284591:YALI0 E07425g
gene id: 284591:YALI0_E07425g
uniprot id: Q6C6P9
names: Similarity
messages: Belongs to the RRP12 family.

284591:YALI0 E29689g
gene id: 284591:YALI0_E29689g
uniprot id: Q6C449
names: Function
names: Similarity
messages: Belongs to the IRS4 family.
messages: Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity).

284591:YALI0 D02717g
gene id: 284591:YALI0_D02717g
uniprot id: Q6CAH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the RSE1 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284591:YALI0 E31449g
gene id: 284591:YALI0_E31449g
uniprot id: Q6C3X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
messages: May form heterododecamers with RVB1. Component of the SWR1 chromatin remodeling complex, the INO80 chromatin remodeling complex, and of the R2TP complex (By similarity).
messages: Nucleus

284591:YALI0 E29733g
gene id: 284591:YALI0_E29733g
uniprot id: Q6C447
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

284591:YALI0 F26499g
gene id: 284591:YALI0_F26499g
uniprot id: Q6C0A2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

284591:YALI0 F24387g
gene id: 284591:YALI0_F24387g
uniprot id: Q6C0I5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

284591:YALI0 E32835g
gene id: 284591:YALI0_E32835g
uniprot id: O74934
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acyl-CoA oxidase family.
messages: Heteropentamer composed of five different subunits.
messages: Peroxisome

284591:YALI0 F02321g
gene id: 284591:YALI0_F02321g
uniprot id: Q6C362
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

284591:YALI0 F04356g
gene id: 284591:YALI0_F04356g
uniprot id: Q6C2X3
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 F09273g
gene id: 284591:YALI0_F09273g
uniprot id: Q6C2B3
names: Function
names: Similarity
messages: Belongs to the dihydroxyacetone kinase (DAK) family.
messages: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.

284591:YALI0 E26345g
gene id: 284591:YALI0_E26345g
uniprot id: Q6C4J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

284591:YALI0 D07590g
gene id: 284591:YALI0_D07590g
uniprot id: Q6C9X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

284591:YALI0 D22484g
gene id: 284591:YALI0_D22484g
uniprot id: Q6C859
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

284591:YALI0 F27819g
gene id: 284591:YALI0_F27819g
uniprot id: Q6C048
names: Similarity
messages: Belongs to the CENP-C/MIF2 family.

284591:YALI0 D13024g
gene id: 284591:YALI0_D13024g
uniprot id: Q6C990
names: Similarity
messages: Belongs to the glutamine synthetase family.

284591:YALI0 B19580g
gene id: 284591:YALI0_B19580g
uniprot id: Q6CE11
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

284591:YALI0 C04521g
gene id: 284591:YALI0_C04521g
uniprot id: Q6CD17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIF1/spd1 family.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 C03069g
gene id: 284591:YALI0_C03069g
uniprot id: Q6CD77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GST superfamily.
messages: Homodimer.
messages: Plays an important role in the cellular response to the nitrogen source.

284591:YALI0 F13629g
gene id: 284591:YALI0_F13629g
uniprot id: F2Z643
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

284591:YALI0 C19448g
gene id: 284591:YALI0_C19448g
uniprot id: Q6CBE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

284591:YALI0 D14080g
gene id: 284591:YALI0_D14080g
uniprot id: Q6C949
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

284591:YALI0 F26323g
gene id: 284591:YALI0_F26323g
uniprot id: Q6C0B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284591:YALI0 E33143g
gene id: 284591:YALI0_E33143g
uniprot id: Q6C3P7
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

284591:YALI0 C13904g
gene id: 284591:YALI0_C13904g
uniprot id: Q6CC02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

284591:YALI0 F04576g
gene id: 284591:YALI0_F04576g
uniprot id: Q6C2W5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

284591:YALI0 B11352g
gene id: 284591:YALI0_B11352g
uniprot id: Q6CF06
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 D26389g
gene id: 284591:YALI0_D26389g
uniprot id: Q6C7P8
names: Function
names: Similarity
messages: Belongs to the endosulfine family.
messages: Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.

284591:YALI0 C04543g
gene id: 284591:YALI0_C04543g
uniprot id: Q6CD16
names: Similarity
messages: Belongs to the TCF25 family.

284591:YALI0 D11418g
gene id: 284591:YALI0_D11418g
uniprot id: Q6C9G4
names: Similarity
messages: Belongs to the AAA ATPase family.

284591:YALI0 B10494g
gene id: 284591:YALI0_B10494g
uniprot id: Q6CF39
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

284591:YALI0 C15323g
gene id: 284591:YALI0_C15323g
uniprot id: B5FVC6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

284591:YALI0 C18447g
gene id: 284591:YALI0_C18447g
uniprot id: Q6CBI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

284591:YALI0 C16478g
gene id: 284591:YALI0_C16478g
uniprot id: Q6CBQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

284591:YALI0 F15983g
gene id: 284591:YALI0_F15983g
uniprot id: Q6C1I4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284591:YALI0 E03762g
gene id: 284591:YALI0_E03762g
uniprot id: Q6C750
names: Similarity
messages: Belongs to the NRDE2 family.

284591:YALI0 E27159g
gene id: 284591:YALI0_E27159g
uniprot id: Q6C4F7
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E17193g
gene id: 284591:YALI0_E17193g
uniprot id: Q6C5K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Nucleus

284591:YALI0 E26785g
gene id: 284591:YALI0_E26785g
uniprot id: Q6C4H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284591:YALI0 E21395g
gene id: 284591:YALI0_E21395g
uniprot id: Q6C534
names: Similarity
messages: Belongs to the TFP11/STIP family.

284591:YALI0 E21021g
gene id: 284591:YALI0_E21021g
uniprot id: Q6C549
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

284591:YALI0 F12969g
gene id: 284591:YALI0_F12969g
uniprot id: Q6C1W0
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

284591:YALI0 D20636g
gene id: 284591:YALI0_D20636g
uniprot id: Q6C8D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 5 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284591:YALI0 E02882g
gene id: 284591:YALI0_E02882g
uniprot id: Q6C784
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus
messages: Pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase.

284591:YALI0 F31548g
gene id: 284591:YALI0_F31548g
uniprot id: B5RSM8
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

284591:YALI0 D08052g
gene id: 284591:YALI0_D08052g
uniprot id: Q6C9V4
names: Similarity
messages: Belongs to the peptidase S10 family.

284591:YALI0 B13838g
gene id: 284591:YALI0_B13838g
uniprot id: F2Z5W7
names: Similarity
messages: Belongs to the cytochrome P450 family.

284591:YALI0 A11869g
gene id: 284591:YALI0_A11869g
uniprot id: Q6CH67
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

284591:YALI0 C11715g
gene id: 284591:YALI0_C11715g
uniprot id: Q6CC77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SNW family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284591:YALI0 C09933g
gene id: 284591:YALI0_C09933g
uniprot id: Q6CCF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEF1 family.
messages: RNA polymerase II degradation factor recruits the ubiquitination machinery to the RNA polymerase II for polyubiquitination, removal and degradation, when RAD26 fails to efficiently displace stalled RNA polymerase II. Also involved in telomere length regulation.
messages: telomere

284591:YALI0 F22121g
gene id: 284591:YALI0_F22121g
uniprot id: Q6C0S5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

284591:YALI0 B01870g
gene id: 284591:YALI0_B01870g
uniprot id: Q6CG09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: nuclear pore complex

284591:YALI0 C18095g
gene id: 284591:YALI0_C18095g
uniprot id: Q6CBK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

284591:YALI0 E30151g
gene id: 284591:YALI0_E30151g
uniprot id: Q6C432
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

284591:YALI0 F02563g
gene id: 284591:YALI0_F02563g
uniprot id: Q6C353
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284591:YALI0 C00847g
gene id: 284591:YALI0_C00847g
uniprot id: Q6CDF9
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C05709g
gene id: 284591:YALI0_C05709g
uniprot id: Q6CCX7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

284591:YALI0 A03597g
gene id: 284591:YALI0_A03597g
uniprot id: Q6CHY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

284591:YALI0 A09922g
gene id: 284591:YALI0_A09922g
uniprot id: Q6CHD7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

284591:YALI0 C06424g
gene id: 284591:YALI0_C06424g
uniprot id: Q6CCU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 F11033g
gene id: 284591:YALI0_F11033g
uniprot id: Q6C243
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

284591:YALI0 C07150g
gene id: 284591:YALI0_C07150g
uniprot id: Q6CCR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

284591:YALI0 B05104g
gene id: 284591:YALI0_B05104g
uniprot id: Q6CFP5
names: Similarity
messages: Belongs to the peptidase M28 family.

284591:YALI0 B12496g
gene id: 284591:YALI0_B12496g
uniprot id: Q6CEV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

284591:YALI0 D23265g
gene id: 284591:YALI0_D23265g
uniprot id: Q6C829
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

284591:YALI0 C08074g
gene id: 284591:YALI0_C08074g
uniprot id: Q6CCN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284591:YALI0 F16896g
gene id: 284591:YALI0_F16896g
uniprot id: Q6C1F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

284591:YALI0 E28853g
gene id: 284591:YALI0_E28853g
uniprot id: Q6C487
names: Similarity
messages: Belongs to the thioesterase PaaI family.

284591:YALI0 B15444g
gene id: 284591:YALI0_B15444g
uniprot id: P38997
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the NAD(+)-dependent cleavage of saccharopine to L-lysine and 2-oxoglutarate, the final step in the alpha-aminoadipate (AAA) pathway for lysin biosynthesis.
messages: Monomer.

284591:YALI0 C19712g
gene id: 284591:YALI0_C19712g
uniprot id: Q6CBD9
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

284591:YALI0 E26367g
gene id: 284591:YALI0_E26367g
uniprot id: Q6C4J0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-B family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Heterotetramer. Consists of 4 subunits: POL2, DPB2, DPB3 and DPB4 (By similarity).
messages: Nucleus
messages: The CysA-type zinc finger is required for PCNA-binding.
messages: The CysB motif binds 1 4Fe-4S cluster and is required for the formation of polymerase complexes.

284591:YALI0 B06369g
gene id: 284591:YALI0_B06369g
uniprot id: Q6CFJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

284591:YALI0 B11814g
gene id: 284591:YALI0_B11814g
uniprot id: Q6CEY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex, which consists of NDC80, NUF2, SPC24 and SPC25.
messages: Nucleus
messages: kinetochore

284591:YALI0 A00891g
gene id: 284591:YALI0_A00891g
uniprot id: Q6CI78
names: Similarity
messages: Belongs to the PPP phosphatase family.

284591:YALI0 F20768g
gene id: 284591:YALI0_F20768g
uniprot id: Q6C0Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

284591:YALI0 E09823g
gene id: 284591:YALI0_E09823g
uniprot id: Q6C6G1
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

284591:YALI0 F17996g
gene id: 284591:YALI0_F17996g
uniprot id: Q6C1A3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A09768g
gene id: 284591:YALI0_A09768g
uniprot id: Q3V7I4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THI4 family.
messages: Binds 1 Fe cation per subunit.
messages: Cytoplasm
messages: During the catalytic reaction, a sulfide is transferred from Cys-206 to a reaction intermediate, generating a dehydroalanine residue.
messages: Homooctamer.
messages: Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
messages: Nucleus

284591:YALI0 D13948g
gene id: 284591:YALI0_D13948g
uniprot id: Q6C953
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.
messages: Nucleus

284591:YALI0 F28435g
gene id: 284591:YALI0_F28435g
uniprot id: Q6C022
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
messages: Component of the Mediator complex.
messages: Nucleus

284591:YALI0 C03608g
gene id: 284591:YALI0_C03608g
uniprot id: Q6CD56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG22 family.
messages: Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation (By similarity).
messages: Vacuole membrane

284591:YALI0 B22946g
gene id: 284591:YALI0_B22946g
uniprot id: Q6CDL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 D22088g
gene id: 284591:YALI0_D22088g
uniprot id: Q6C874
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

284591:YALI0 B04598g
gene id: 284591:YALI0_B04598g
uniprot id: Q6CFR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG11 family.
messages: Homodimer.
messages: Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion (By similarity).
messages: Preautophagosomal structure membrane
messages: Vacuole membrane

284591:YALI0 D17006g
gene id: 284591:YALI0_D17006g
uniprot id: Q6C8U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CHS7 family.
messages: Chaperone required for the export of the chitin synthase CHS3 from the endoplasmic reticulum.
messages: Endoplasmic reticulum membrane
messages: Interacts with CHS3.

284591:YALI0 D01914g
gene id: 284591:YALI0_D01914g
uniprot id: Q6CAK9
names: Similarity
messages: Belongs to the RMD1/sif2 family.

284591:YALI0 E14575g
gene id: 284591:YALI0_E14575g
uniprot id: Q6C5W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 E23584g
gene id: 284591:YALI0_E23584g
uniprot id: Q6C4U6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

284591:YALI0 A01562g
gene id: 284591:YALI0_A01562g
uniprot id: Q6CI53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Nucleus

284591:YALI0 B16720g
gene id: 284591:YALI0_B16720g
uniprot id: Q6CEC6
names: Similarity
messages: Belongs to the phospholipid scramblase family.

284591:YALI0 D04488g
gene id: 284591:YALI0_D04488g
uniprot id: P45816
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro.

284591:YALI0 D11572g
gene id: 284591:YALI0_D11572g
uniprot id: Q6C9F7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

284591:YALI0 E00198g
gene id: 284591:YALI0_E00198g
uniprot id: Q6C7J9
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

284591:YALI0 C09350g
gene id: 284591:YALI0_C09350g
uniprot id: Q6CCH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX20 family.
messages: Involved in the assembly of the cytochrome c oxidase complex.
messages: Mitochondrion inner membrane

284591:YALI0 F25289g
gene id: 284591:YALI0_F25289g
uniprot id: Q6C0E9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

284591:YALI0 E20273g
gene id: 284591:YALI0_E20273g
uniprot id: Q6C581
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F14839g
gene id: 284591:YALI0_F14839g
uniprot id: Q6C1N1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

284591:YALI0 E29975g
gene id: 284591:YALI0_E29975g
uniprot id: Q6C438
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

284591:YALI0 B09779g
gene id: 284591:YALI0_B09779g
uniprot id: Q6CF69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with nucleolar and cytoplasmic pre-60S particles. At the end of biogenesis it dissociates from cytoplasmic pre-60S particles and is likely to be exchanged for its ribosomal homolog, RPL24.
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Cytoplasm
messages: Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of YALI0_B00990g/NOG1 to pre-60S particles. Activates and recruits ATPase AFG2 to cytoplasmic pre-60S ribosomal particles.
messages: Nucleus

284591:YALI0 A10593g
gene id: 284591:YALI0_A10593g
uniprot id: Q6CHB2
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D14740g
gene id: 284591:YALI0_D14740g
uniprot id: Q9HFC8
names: Caution
names: Function
names: Similarity
messages: Belongs to the peptidase C2 family. PalB/RIM13 subfamily.
messages: It is uncertain whether Met-1 or Met-12 is the initiator.
messages: Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.

284591:YALI0 A09064g
gene id: 284591:YALI0_A09064g
uniprot id: Q6CHG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

284591:YALI0 A01133g
gene id: 284591:YALI0_A01133g
uniprot id: Q6CI67
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

284591:YALI0 C16621g
gene id: 284591:YALI0_C16621g
uniprot id: Q6CBQ1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

284591:YALI0 F12815g
gene id: 284591:YALI0_F12815g
uniprot id: Q6C1W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

284591:YALI0 E13123g
gene id: 284591:YALI0_E13123g
uniprot id: Q6C624
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

284591:YALI0 F08701g
gene id: 284591:YALI0_F08701g
uniprot id: Q6C2D9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
messages: Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.

284591:YALI0 E16126g
gene id: 284591:YALI0_E16126g
uniprot id: Q6C5Q5
names: Similarity
messages: Belongs to the AFG1 ATPase family.

284591:YALI0 F29205g
gene id: 284591:YALI0_F29205g
uniprot id: Q6C002
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

284591:YALI0 F14355g
gene id: 284591:YALI0_F14355g
uniprot id: Q6C1Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

284591:YALI0 F03751g
gene id: 284591:YALI0_F03751g
uniprot id: Q6C300
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B01771g
gene id: 284591:YALI0_B01771g
uniprot id: B5FVA8
names: Similarity
messages: Belongs to the lysophospholipase family.

284591:YALI0 F27555g
gene id: 284591:YALI0_F27555g
uniprot id: Q6C060
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

284591:YALI0 E31911g
gene id: 284591:YALI0_E31911g
uniprot id: Q6C3V2
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

284591:YALI0 E29403g
gene id: 284591:YALI0_E29403g
uniprot id: Q6C462
names: Activity Regulation
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Cytoplasm
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

284591:YALI0 D07084g
gene id: 284591:YALI0_D07084g
uniprot id: Q6C9Z7
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.
messages: Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P).

284591:YALI0 D11352g
gene id: 284591:YALI0_D11352g
uniprot id: Q6C9G7
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 F15235g
gene id: 284591:YALI0_F15235g
uniprot id: Q6C1L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PINX1 family.
messages: Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.
messages: nucleolus

284591:YALI0 E33377g
gene id: 284591:YALI0_E33377g
uniprot id: Q6C3N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Chromosome
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Nucleus

284591:YALI0 D07700g
gene id: 284591:YALI0_D07700g
uniprot id: Q6C9W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
messages: Belongs to the dynein light chain family.
messages: Cytoplasmic dynein consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits which present intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs).
messages: cytoskeleton
messages: nuclear pore complex

284591:YALI0 E32637g
gene id: 284591:YALI0_E32637g
uniprot id: Q6C3R8
names: Similarity
messages: Belongs to the OPI10 family.

284591:YALI0 C06578g
gene id: 284591:YALI0_C06578g
uniprot id: Q6CCT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

284591:YALI0 D03509g
gene id: 284591:YALI0_D03509g
uniprot id: Q6CAE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 E10219g
gene id: 284591:YALI0_E10219g
uniprot id: Q6C6E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

284591:YALI0 B18326g
gene id: 284591:YALI0_B18326g
uniprot id: Q6CE60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NOP16 family.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

284591:YALI0 C19041g
gene id: 284591:YALI0_C19041g
uniprot id: Q6CBG6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

284591:YALI0 B18656g
gene id: 284591:YALI0_B18656g
uniprot id: Q6CE45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYS1 family.
messages: Golgi apparatus membrane
messages: Membrane

284591:YALI0 D23551g
gene id: 284591:YALI0_D23551g
uniprot id: Q6C818
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with nucleolar pre-ribosomal particles.
messages: Belongs to the RSA3 family.
messages: Required for efficient biogenesis of the 60S ribosomal subunit.
messages: nucleolus

284591:YALI0 F17864g
gene id: 284591:YALI0_F17864g
uniprot id: Q6C1A7
names: Function
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.
messages: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

284591:YALI0 F19074g
gene id: 284591:YALI0_F19074g
uniprot id: Q6C157
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

284591:YALI0 E32109g
gene id: 284591:YALI0_E32109g
uniprot id: Q6C3U2
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 B01144g
gene id: 284591:YALI0_B01144g
uniprot id: Q6CG38
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

284591:YALI0 D04026g
gene id: 284591:YALI0_D04026g
uniprot id: F2Z5Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

284591:YALI0 D05687g
gene id: 284591:YALI0_D05687g
uniprot id: Q6CA58
names: Similarity
messages: Belongs to the MGMT family.

284591:YALI0 F14113g
gene id: 284591:YALI0_F14113g
uniprot id: Q6C1R4
names: Similarity
messages: Belongs to the lysophospholipase family.

284591:YALI0 B10582g
gene id: 284591:YALI0_B10582g
uniprot id: Q6CF35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer; composed of two copies of TRM6 and two copies of TRM61.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

284591:YALI0 B16126g
gene id: 284591:YALI0_B16126g
uniprot id: Q6CEF2
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

284591:YALI0 C21043g
gene id: 284591:YALI0_C21043g
uniprot id: Q6CB90
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

284591:YALI0 F28501g
gene id: 284591:YALI0_F28501g
uniprot id: Q6C019
names: Similarity
messages: Belongs to the importin alpha family.

284591:YALI0 E09012g
gene id: 284591:YALI0_E09012g
uniprot id: Q6C6J7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

284591:YALI0 F01903g
gene id: 284591:YALI0_F01903g
uniprot id: Q6C381
names: Similarity
messages: Belongs to the peptidase C19 family.

284591:YALI0 D14300g
gene id: 284591:YALI0_D14300g
uniprot id: Q6C947
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 C10945g
gene id: 284591:YALI0_C10945g
uniprot id: Q6CCB1
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

284591:YALI0 C05753g
gene id: 284591:YALI0_C05753g
uniprot id: Q6CCX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 F05808g
gene id: 284591:YALI0_F05808g
uniprot id: Q6C2R2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

284591:YALI0 C17325g
gene id: 284591:YALI0_C17325g
uniprot id: Q6CBM3
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

284591:YALI0 E13277g
gene id: 284591:YALI0_E13277g
uniprot id: Q6C617
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
messages: Cytoplasm

284591:YALI0 F16335g
gene id: 284591:YALI0_F16335g
uniprot id: Q6C1H0
names: Similarity
messages: Belongs to the TOP6A family.

284591:YALI0 B10604g
gene id: 284591:YALI0_B10604g
uniprot id: Q6CF34
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

284591:YALI0 E15928g
gene id: 284591:YALI0_E15928g
uniprot id: Q6C5R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Nucleus

284591:YALI0 C14344g
gene id: 284591:YALI0_C14344g
uniprot id: Q6CBY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284591:YALI0 E06941g
gene id: 284591:YALI0_E06941g
uniprot id: Q6C6R3
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

284591:YALI0 D06303g
gene id: 284591:YALI0_D06303g
uniprot id: Q6CA33
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

284591:YALI0 C23210g
gene id: 284591:YALI0_C23210g
uniprot id: Q6CAZ2
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

284591:YALI0 F02805g
gene id: 284591:YALI0_F02805g
uniprot id: Q6C342
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

284591:YALI0 B04136g
gene id: 284591:YALI0_B04136g
uniprot id: Q6CFT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity).
messages: nucleolus

284591:YALI0 B21142g
gene id: 284591:YALI0_B21142g
uniprot id: Q6CDU4
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F06446g
gene id: 284591:YALI0_F06446g
uniprot id: Q6C2N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the STAM family.
messages: Component of the ESCRT-0 complex composed of HSE1 and VPS27.
messages: Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).
messages: Endosome membrane

284591:YALI0 A10274g
gene id: 284591:YALI0_A10274g
uniprot id: Q6CHC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 E00814g
gene id: 284591:YALI0_E00814g
uniprot id: Q8J0I8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alternative oxidase family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures (By similarity).
messages: Mitochondrion inner membrane

284591:YALI0 B07667g
gene id: 284591:YALI0_B07667g
uniprot id: F2Z5Z5
names: Similarity
messages: Belongs to the TrpF family.

284591:YALI0 D06237g
gene id: 284591:YALI0_D06237g
uniprot id: Q6CA36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Delta(4)-fatty-acid desaturase which introduces a double bond at the 4-position in the long-chain base (LCB) of ceramides.
messages: Membrane

284591:YALI0 F03179g
gene id: 284591:YALI0_F03179g
uniprot id: Q6C326
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATP synthases have 2 components, the catalytic core F(1) and the membrane-embedded component F(0), linked together by a central stalk and a peripheral stalk (PubMed:27373333). The central stalk, also called rotor shaft, is often seen as part of F(1) (PubMed:27373333). The peripheral stalk is seen as part of F(0) (PubMed:27373333). F(0) contains the membrane channel next to the rotor (PubMed:27373333). F-type ATP synthases form dimers but each monomer functions independently in ATP generation (PubMed:27373333). The dimer consists of 17 different polypeptides: ATP1 (subunit alpha, 3 molecules per monomer, part of F(1)), ATP2 (subunit beta, 3 copies per monomer, part of F(1)), ATP3 (subunit gamma, part of the central stalk), ATP4 (subunit b, part of the peripheral stalk), ATP5/OSCP (subunit 5/OSCP, part of the peripheral stalk), ATP6 (subunit a, part of the peripheral stalk), ATP7 (subunit d, part of the peripheral stalk), ATP8 (subunit 8, part of the peripheral stalk), OLI1 (subunit c, part of the rotor, 10 molecules per monomer), ATP14 (subunit h, part of the peripheral stalk), ATP15 (subunit epsilon, part of the central stalk), ATP16 (subunit delta, part of the central stalk), ATP17 (subunit f, part of the peripheral stalk), ATP18 (subunit i/j, part of the peripheral stalk), ATP19 (subunit k, dimer-specific, at interface between monomers), ATP20 (subunit g, at interface between monomers), TIM11 (subunit e, at interface between monomers) (PubMed:27373333, PubMed:25759169).
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169). F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27373333). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (PubMed:27373333). Subunits alpha/ATP1 and beta/ATP2 form the catalytic core in F(1) (PubMed:27373333). Rotation of the central stalk against the surrounding alpha/ATP1(3)beta/ATP2(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta/ATP2 subunits (PubMed:27373333). Subunit alpha/ATP1 does not bear the catalytic high-affinity ATP-binding sites (PubMed:27373333).
messages: Mitochondrion inner membrane

284591:YALI0 C19063g
gene id: 284591:YALI0_C19063g
uniprot id: Q6CBG5
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 D16753g
gene id: 284591:YALI0_D16753g
uniprot id: Q6C8V3
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

284591:YALI0 B15334g
gene id: 284591:YALI0_B15334g
uniprot id: Q6CEI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

284591:YALI0 F09691g
gene id: 284591:YALI0_F09691g
uniprot id: Q6C293
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284591:YALI0 A03883g
gene id: 284591:YALI0_A03883g
uniprot id: Q6CHX1
names: Similarity
messages: Belongs to the nucleoporin Nup133 family.

284591:YALI0 C21789g
gene id: 284591:YALI0_C21789g
uniprot id: B5FVD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Mitochondrion inner membrane

284591:YALI0 C24145g
gene id: 284591:YALI0_C24145g
uniprot id: Q6CAV0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 E04697g
gene id: 284591:YALI0_E04697g
uniprot id: Q6C709
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the WD repeat PRL1/PRL2 family.
messages: Cytoplasm
messages: Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.
messages: Nucleus

284591:YALI0 B14333g
gene id: 284591:YALI0_B14333g
uniprot id: Q6CEN3
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

284591:YALI0 F21681g
gene id: 284591:YALI0_F21681g
uniprot id: Q6C0U5
names: Similarity
messages: Belongs to the SEC3 family.

284591:YALI0 F09251g
gene id: 284591:YALI0_F09251g
uniprot id: Q6C2B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

284591:YALI0 D12254g
gene id: 284591:YALI0_D12254g
uniprot id: Q6C9C7
names: Similarity
messages: Belongs to the complex I LYR family.

284591:YALI0 E33759g
gene id: 284591:YALI0_E33759g
uniprot id: Q6C3L8
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

284591:YALI0 D26345g
gene id: 284591:YALI0_D26345g
uniprot id: Q6C7Q0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.
messages: The DHHC domain is required for palmitoyltransferase activity.

284591:YALI0 E31383g
gene id: 284591:YALI0_E31383g
uniprot id: Q6C3X9
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E00902g
gene id: 284591:YALI0_E00902g
uniprot id: Q6C7H0
names: Similarity
messages: Belongs to the MYBBP1A family.

284591:YALI0 F15587g
gene id: 284591:YALI0_F15587g
uniprot id: Q6C1K2
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

284591:YALI0 F13299g
gene id: 284591:YALI0_F13299g
uniprot id: Q6C1U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

284591:YALI0 B08074g
gene id: 284591:YALI0_B08074g
uniprot id: Q6CFD6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

284591:YALI0 F23089g
gene id: 284591:YALI0_F23089g
uniprot id: Q6C0N8
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A18832g
gene id: 284591:YALI0_A18832g
uniprot id: Q6CGJ2
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

284591:YALI0 F08195g
gene id: 284591:YALI0_F08195g
uniprot id: Q6C2G0
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

284591:YALI0 E32131g
gene id: 284591:YALI0_E32131g
uniprot id: Q6C3U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with missfolded ER lumenal proteins.
messages: Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation (By similarity).

284591:YALI0 F26697g
gene id: 284591:YALI0_F26697g
uniprot id: Q6C093
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin-conjugating enzyme family.
messages: Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 F03575g
gene id: 284591:YALI0_F03575g
uniprot id: Q6C308
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 15 family.
messages: Nucleus

284591:YALI0 F25069g
gene id: 284591:YALI0_F25069g
uniprot id: Q6C0F9
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

284591:YALI0 C10780g
gene id: 284591:YALI0_C10780g
uniprot id: Q6CCB9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284591:YALI0 F12991g
gene id: 284591:YALI0_F12991g
uniprot id: Q6C1V9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

284591:YALI0 E18942g
gene id: 284591:YALI0_E18942g
uniprot id: Q6C5D6
names: Similarity
messages: Belongs to the polyprenol kinase family.

284591:YALI0 D21912g
gene id: 284591:YALI0_D21912g
uniprot id: Q6C882
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CLASP family.
messages: Interacts with microtubules.
messages: Microtubule binding protein that promotes the stabilization of dynamic microtubules. Required for mitotic spindle formation (By similarity).
messages: Nucleus
messages: cytoskeleton
messages: spindle

284591:YALI0 B07007g
gene id: 284591:YALI0_B07007g
uniprot id: Q6CFH1
names: Similarity
messages: Belongs to the WrbA family.

284591:YALI0 D01111g
gene id: 284591:YALI0_D01111g
uniprot id: Q6CAP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 B17930g
gene id: 284591:YALI0_B17930g
uniprot id: Q6CE75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

284591:YALI0 F31119g
gene id: 284591:YALI0_F31119g
uniprot id: Q6BZT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

284591:YALI0 B16698g
gene id: 284591:YALI0_B16698g
uniprot id: Q6CEC7
names: Similarity
messages: Belongs to the peptidase C12 family.

284591:YALI0 C08030g
gene id: 284591:YALI0_C08030g
uniprot id: Q6CCN2
names: Similarity
messages: Belongs to the PHF5 family.

284591:YALI0 F25905g
gene id: 284591:YALI0_F25905g
uniprot id: Q6C0C4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation of histone H3 leads to transcriptional activation. Acetylated by GCN5 to form H3K14ac. H3K14ac can also be formed by ESA1. H3K56ac formation occurs predominantly in newly synthesized H3 molecules during G1, S and G2/M of the cell cycle and may be involved in DNA repair (By similarity).
messages: Belongs to the histone H3 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).
messages: Mono-, di- and trimethylated by the COMPASS complex to form H3K4me1/2/3. H3K4me activates gene expression by regulating transcription elongation and plays a role in telomere length maintenance. H3K4me enrichment correlates with transcription levels, and occurs in a 5' to 3' gradient with H3K4me3 enrichment at the 5'-end of genes, shifting to H3K4me2 and then H3K4me1. Methylated by SET2 to form H3K36me. H3K36me represses gene expression. Methylated by DOT1 to form H3K79me. H3K79me is required for association of SIR proteins with telomeric regions and for telomeric silencing. The COMPASS-mediated formation of H3K4me2/3 and the DOT1-mediated formation of H3K79me require H2BK123ub1 (By similarity).
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA (By similarity).
messages: To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H3K4me1/2/3 = mono-, di- and trimethylated Lys-5; H3K9ac = acetylated Lys-12; H3K9me1 = monomethylated Lys-12; H3K14ac = acetylated Lys-17; H3K14me2 = dimethylated Lys-17; H3K18ac = acetylated Lys-21; H3K18me1 = monomethylated Lys-21; H3K23ac = acetylated Lys-26; H3K23me1 = monomethylated Lys-26; H3K27ac = acetylated Lys-30; H3K27me1/2/3 = mono-, di- and trimethylated Lys-30; H3K36ac = acetylated Lys-40; H3K36me1/2/3 = mono-, di- and trimethylated Lys-40; H3K56ac = acetylated Lys-62; H3K64ac = acetylated Lys-70; H3K79me1/2/3 = mono-, di- and trimethylated Lys-85.

284591:YALI0 B02816g
gene id: 284591:YALI0_B02816g
uniprot id: Q6CFX3
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

284591:YALI0 B02684g
gene id: 284591:YALI0_B02684g
uniprot id: Q6CFX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane

284591:YALI0 D06864g
gene id: 284591:YALI0_D06864g
uniprot id: Q6CA07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

284591:YALI0 C10824g
gene id: 284591:YALI0_C10824g
uniprot id: Q6CCB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC5 family.
messages: Nucleus

284591:YALI0 A20768g
gene id: 284591:YALI0_A20768g
uniprot id: Q6CGB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Nucleus

284591:YALI0 D05929g
gene id: 284591:YALI0_D05929g
uniprot id: Q6CA49
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284591:YALI0 F05456g
gene id: 284591:YALI0_F05456g
uniprot id: Q6C2S9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Prevacuolar compartment membrane
messages: Required for retention of late Golgi membrane proteins. Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane proteins during the sorting/budding process at the prevacuolar compartment. Binds phosphatidylinositol 3-phosphate (PtdIns(P3)) (By similarity).
messages: The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization.

284591:YALI0 B00220g
gene id: 284591:YALI0_B00220g
uniprot id: Q6CG74
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

284591:YALI0 D07216g
gene id: 284591:YALI0_D07216g
uniprot id: Q6C9Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I LYR family.
messages: Mitochondrion inner membrane

284591:YALI0 B01540g
gene id: 284591:YALI0_B01540g
uniprot id: Q6CG23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 D20922g
gene id: 284591:YALI0_D20922g
uniprot id: Q6C8C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

284591:YALI0 E13706g
gene id: 284591:YALI0_E13706g
uniprot id: Q99170
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Endoplasmic reticulum lumen
messages: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.
messages: The chaperone activity is regulated by ATP-induced allosteric coupling of the nucleotide-binding (NBD) and substrate-binding (SBD) domains. In the ADP-bound and nucleotide-free (apo) states, the two domains have little interaction. In contrast, in the ATP-bound state the two domains are tightly coupled, which results in drastically accelerated kinetics in both binding and release of polypeptide substrates. J domain-containing co-chaperones stimulate the ATPase activity and are required for efficient substrate recognition.

284591:YALI0 E00242g
gene id: 284591:YALI0_E00242g
uniprot id: Q6C7J7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

284591:YALI0 E26323g
gene id: 284591:YALI0_E26323g
uniprot id: Q6C4J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

284591:YALI0 B13640g
gene id: 284591:YALI0_B13640g
uniprot id: P78978
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by C-terminal proteolytic cleavage by signaling protease (probably palB/RIM13) at neutral to alkaline ambient pH.
messages: Belongs to the pacC/RIM101 family.
messages: Binds to DNA. Interacts with RIM20, which binds to the two YPX[LI] motifs and is required for proteolytic processing (By similarity).
messages: Cytoplasm
messages: Nucleus
messages: Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including RIM101 itself) and represses transcription of acid-expressed genes, thereby regulating the synthesis and secretion of alkaline protease XPR2 and acidic protease AXP1 depending on ambient pH. Specifically recognizes and binds the consensus sequence 5'-GCCARG-3'. Required for mating and sporulation.

284591:YALI0 E04070g
gene id: 284591:YALI0_E04070g
uniprot id: Q6C736
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

284591:YALI0 B17072g
gene id: 284591:YALI0_B17072g
uniprot id: Q6CEB0
names: Similarity
messages: Belongs to the peptidase C19 family.

284591:YALI0 E02398g
gene id: 284591:YALI0_E02398g
uniprot id: Q6C7A4
names: Similarity
messages: Belongs to the oxoprolinase family.

284591:YALI0 E13101g
gene id: 284591:YALI0_E13101g
uniprot id: Q6C625
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus

284591:YALI0 E15400g
gene id: 284591:YALI0_E15400g
uniprot id: Q6C5T1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

284591:YALI0 B07205g
gene id: 284591:YALI0_B07205g
uniprot id: Q6CFG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: Membrane

284591:YALI0 E10879g
gene id: 284591:YALI0_E10879g
uniprot id: Q6C6B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

284591:YALI0 C06149g
gene id: 284591:YALI0_C06149g
uniprot id: Q6CCV7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

284591:YALI0 D08888g
gene id: 284591:YALI0_D08888g
uniprot id: Q6C9R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

284591:YALI0 C16027g
gene id: 284591:YALI0_C16027g
uniprot id: Q6CBS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A component of the endosomal sorting required for transport complex III (ESCRT-III).
messages: Belongs to the SNF7 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB). Also required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH (By similarity).

284591:YALI0 A17020g
gene id: 284591:YALI0_A17020g
uniprot id: Q6CGR5
names: Similarity
messages: Belongs to the EIS1 family.

284591:YALI0 C23034g
gene id: 284591:YALI0_C23034g
uniprot id: Q6CB00
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

284591:YALI0 E26829g
gene id: 284591:YALI0_E26829g
uniprot id: Q6C4H2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

284591:YALI0 C20141g
gene id: 284591:YALI0_C20141g
uniprot id: Q6CBC2
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

284591:YALI0 F27973g
gene id: 284591:YALI0_F27973g
uniprot id: Q6C041
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

284591:YALI0 E17325g
gene id: 284591:YALI0_E17325g
uniprot id: Q6C5K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDS23 family.
messages: Cytoplasm
messages: Involved in DNA replication and cell separation.
messages: Nucleus

284591:YALI0 E12551g
gene id: 284591:YALI0_E12551g
uniprot id: Q6C644
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F31207g
gene id: 284591:YALI0_F31207g
uniprot id: Q6BZS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

284591:YALI0 C10230g
gene id: 284591:YALI0_C10230g
uniprot id: Q6CCD9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

284591:YALI0 E08096g
gene id: 284591:YALI0_E08096g
uniprot id: Q6C6M7
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B18590g
gene id: 284591:YALI0_B18590g
uniprot id: Q6CE48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Mitochondrion inner membrane
messages: Required for the effective assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). Probably facilitates the assembly of Fe-S cofactors and subunits of complex I.

284591:YALI0 B17996g
gene id: 284591:YALI0_B17996g
uniprot id: Q6CE74
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

284591:YALI0 E07073g
gene id: 284591:YALI0_E07073g
uniprot id: Q6C6R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

284591:YALI0 D01353g
gene id: 284591:YALI0_D01353g
uniprot id: Q6CAN0
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 C06996g
gene id: 284591:YALI0_C06996g
uniprot id: Q6CCS2
names: Similarity
messages: Belongs to the PPC synthetase family.

284591:YALI0 F22605g
gene id: 284591:YALI0_F22605g
uniprot id: Q6C0Q5
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Homotetramer.

284591:YALI0 D20702g
gene id: 284591:YALI0_D20702g
uniprot id: Q6C8C8
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 B12848g
gene id: 284591:YALI0_B12848g
uniprot id: Q6CEU5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

284591:YALI0 D26279g
gene id: 284591:YALI0_D26279g
uniprot id: Q6C7Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
messages: Component of the HAT-B complex composed of at least HAT1 and HAT2. The HAT-B complex binds to histone H4 tail (By similarity).
messages: Cytoplasm
messages: Nucleus
messages: Regulatory subunit of the histone acetylase B (HAT-B) complex. The complex acetylates 'Lys-12' of histone H4 which is required for telomeric silencing (By similarity).

284591:YALI0 C19129g
gene id: 284591:YALI0_C19129g
uniprot id: Q6CBG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC4 subfamily.
messages: Nucleus

284591:YALI0 B16544g
gene id: 284591:YALI0_B16544g
uniprot id: Q6CED4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

284591:YALI0 D23969g
gene id: 284591:YALI0_D23969g
uniprot id: Q6C7Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.
messages: Homodimer.

284591:YALI0 B02706g
gene id: 284591:YALI0_B02706g
uniprot id: Q6CFX8
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

284591:YALI0 B07183g
gene id: 284591:YALI0_B07183g
uniprot id: W0TYP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
messages: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.

284591:YALI0 F25399g
gene id: 284591:YALI0_F25399g
uniprot id: Q6C0E7
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

284591:YALI0 D16885g
gene id: 284591:YALI0_D16885g
uniprot id: Q6C8U7
names: Similarity
messages: Belongs to the APC1 family.

284591:YALI0 E20493g
gene id: 284591:YALI0_E20493g
uniprot id: Q6C573
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

284591:YALI0 F16687g
gene id: 284591:YALI0_F16687g
uniprot id: Q6C1F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

284591:YALI0 F27775g
gene id: 284591:YALI0_F27775g
uniprot id: Q6C050
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAC3 family.
messages: Nucleus envelope

284591:YALI0 F05060g
gene id: 284591:YALI0_F05060g
uniprot id: Q6C2U6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C10311g
gene id: 284591:YALI0_C10311g
uniprot id: Q6CCD6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A07403g
gene id: 284591:YALI0_A07403g
uniprot id: Q6CHM2
names: Similarity
messages: Belongs to the Rho GDI family.

284591:YALI0 E34265g
gene id: 284591:YALI0_E34265g
uniprot id: Q6C3J7
names: Similarity
messages: Belongs to the catalase family.

284591:YALI0 C03443g
gene id: 284591:YALI0_C03443g
uniprot id: Q6CD64
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

284591:YALI0 F22671g
gene id: 284591:YALI0_F22671g
uniprot id: Q6C0Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

284591:YALI0 D12210g
gene id: 284591:YALI0_D12210g
uniprot id: Q6C9C9
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

284591:YALI0 E23991g
gene id: 284591:YALI0_E23991g
uniprot id: Q6C4T0
names: Similarity
messages: Belongs to the NAD kinase family.

284591:YALI0 C01411g
gene id: 284591:YALI0_C01411g
uniprot id: Q6CDD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

284591:YALI0 D09823g
gene id: 284591:YALI0_D09823g
uniprot id: Q6C9N0
names: Function
names: Similarity
messages: Belongs to the WD repeat DSE1 family.
messages: Involved in cell wall metabolism and required for the separation of the mother and daughter cells.

284591:YALI0 C17369g
gene id: 284591:YALI0_C17369g
uniprot id: Q6CBM1
names: Similarity
messages: Belongs to the Cdt1 family.

284591:YALI0 E34133g
gene id: 284591:YALI0_E34133g
uniprot id: Q6C3K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Endoplasmic reticulum membrane
messages: Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER (By similarity).

284591:YALI0 F05896g
gene id: 284591:YALI0_F05896g
uniprot id: Q6C2Q8
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E33363g
gene id: 284591:YALI0_E33363g
uniprot id: Q6C3N7
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 A19756g
gene id: 284591:YALI0_A19756g
uniprot id: Q6CGF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

284591:YALI0 C10494g
gene id: 284591:YALI0_C10494g
uniprot id: Q6CCD1
names: Similarity
messages: Belongs to the peptidase M18 family.

284591:YALI0 E03608g
gene id: 284591:YALI0_E03608g
uniprot id: Q6C756
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

284591:YALI0 E16599g
gene id: 284591:YALI0_E16599g
uniprot id: P78980
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Peroxisome membrane

284591:YALI0 B11726g
gene id: 284591:YALI0_B11726g
uniprot id: Q6CEZ1
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

284591:YALI0 C19965g
gene id: 284591:YALI0_C19965g
uniprot id: Q6CBC8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284591:YALI0 E25135g
gene id: 284591:YALI0_E25135g
uniprot id: Q6C4M9
names: Activity Regulation
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Activated by tyrosine and threonine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.
messages: Cytoplasm
messages: Dually phosphorylated on Thr-171 and Tyr-173, which activates the enzyme.
messages: Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes (By similarity).
messages: Nucleus
messages: The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.

284591:YALI0 C09636g
gene id: 284591:YALI0_C09636g
uniprot id: Q6CCG2
names: Similarity
messages: Belongs to the acetolactate synthase small subunit family.

284591:YALI0 E21351g
gene id: 284591:YALI0_E21351g
uniprot id: Q6C536
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

284591:YALI0 F06578g
gene id: 284591:YALI0_F06578g
uniprot id: Q6C2M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Sterol O-acyltransferase that catalyzes the formation of stery esters.

284591:YALI0 E33033g
gene id: 284591:YALI0_E33033g
uniprot id: Q6C3Q2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

284591:YALI0 F21879g
gene id: 284591:YALI0_F21879g
uniprot id: Q6C0T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 A11473g
gene id: 284591:YALI0_A11473g
uniprot id: Q6CH81
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B09625g
gene id: 284591:YALI0_B09625g
uniprot id: Q6CF75
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

284591:YALI0 B08866g
gene id: 284591:YALI0_B08866g
uniprot id: Q6CFA4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

284591:YALI0 E14366g
gene id: 284591:YALI0_E14366g
uniprot id: Q6C5X3
names: Similarity
messages: Belongs to the WrbA family.

284591:YALI0 A19580g
gene id: 284591:YALI0_A19580g
uniprot id: Q6CGG4
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D21142g
gene id: 284591:YALI0_D21142g
uniprot id: Q6C8B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

284591:YALI0 B09427g
gene id: 284591:YALI0_B09427g
uniprot id: Q6CF83
names: Similarity
messages: Belongs to the peptidase M20A family.

284591:YALI0 D00132g
gene id: 284591:YALI0_D00132g
uniprot id: Q6CAT5
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284591:YALI0 E22462g
gene id: 284591:YALI0_E22462g
uniprot id: Q6C4Z3
names: Similarity
messages: Belongs to the lysophospholipase family.

284591:YALI0 E01364g
gene id: 284591:YALI0_E01364g
uniprot id: Q6C7F0
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

284591:YALI0 E09350g
gene id: 284591:YALI0_E09350g
uniprot id: Q6CHG3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

284591:YALI0 D08756g
gene id: 284591:YALI0_D08756g
uniprot id: Q6C9S4
names: Similarity
messages: Belongs to the XPC family.

284591:YALI0 A17666g
gene id: 284591:YALI0_A17666g
uniprot id: Q6CGP0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F27093g
gene id: 284591:YALI0_F27093g
uniprot id: Q6C079
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.
messages: Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5.
messages: Nucleus

284591:YALI0 B02574g
gene id: 284591:YALI0_B02574g
uniprot id: Q6CFY2
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

284591:YALI0 F20746g
gene id: 284591:YALI0_F20746g
uniprot id: Q6C0Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

284591:YALI0 D16687g
gene id: 284591:YALI0_D16687g
uniprot id: Q6C8V5
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

284591:YALI0 E33253g
gene id: 284591:YALI0_E33253g
uniprot id: Q6C3P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

284591:YALI0 C17017g
gene id: 284591:YALI0_C17017g
uniprot id: Q6CBN3
names: Similarity
messages: Belongs to the MT-A70-like family.

284591:YALI0 E31766g
gene id: 284591:YALI0_E31766g
uniprot id: B5FVG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

284591:YALI0 E26719g
gene id: 284591:YALI0_E26719g
uniprot id: Q6C4H7
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

284591:YALI0 B13530g
gene id: 284591:YALI0_B13530g
uniprot id: Q6CER8
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

284591:YALI0 E10131g
gene id: 284591:YALI0_E10131g
uniprot id: Q6C6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

284591:YALI0 F24497g
gene id: 284591:YALI0_F24497g
uniprot id: Q6C0I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity).
messages: Component of the U3 snoRNP particle. Binds to the C'/D and B/C motifs in U3 snoRNA. Component of the 25S U4/U6.U5 tri-snRNP particle, a subcomplex of the spliceosome. Binds to the 5' stem-loop of U4 snRNA (By similarity).
messages: nucleolus

284591:YALI0 F20196g
gene id: 284591:YALI0_F20196g
uniprot id: Q6C110
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

284591:YALI0 E25894g
gene id: 284591:YALI0_E25894g
uniprot id: Q6C4K9
names: Similarity
messages: Belongs to the glycosyltransferase 34 family.

284591:YALI0 B22902g
gene id: 284591:YALI0_B22902g
uniprot id: Q6CDM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.

284591:YALI0 A20702g
gene id: 284591:YALI0_A20702g
uniprot id: Q6CGB3
names: Subcellular Location Annotation
messages: Nucleus membrane

284591:YALI0 F28369g
gene id: 284591:YALI0_F28369g
uniprot id: Q6C025
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E29205g
gene id: 284591:YALI0_E29205g
uniprot id: Q6C472
names: Similarity
messages: Belongs to the peptidase M28 family.

284591:YALI0 E17457g
gene id: 284591:YALI0_E17457g
uniprot id: Q6C5J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284591:YALI0 F15059g
gene id: 284591:YALI0_F15059g
uniprot id: Q6C1M1
names: Similarity
messages: Belongs to the ADIP family.

284591:YALI0 F05918g
gene id: 284591:YALI0_F05918g
uniprot id: Q6C2Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM RBM34 family.
messages: Involved in pre-25S rRNA processing.
messages: nucleolus

284591:YALI0 A10362g
gene id: 284591:YALI0_A10362g
uniprot id: Q6CHC0
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

284591:YALI0 E24453g
gene id: 284591:YALI0_E24453g
uniprot id: Q6C4Q9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG3 family.
messages: Cytoplasm
messages: E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8. The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8 from ATG3 to phosphatidylethanolamine (PE). This step is required for the membrane association of ATG8. The formation of the ATG8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt). The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity).
messages: Monomer. Interacts with ATG8 through an intermediate thioester bond through the C-terminal Gly of ATG8. Also interacts with the 40 amino acid C-terminal region of the E1-like ATG7 enzyme. Interacts also with the ATG12-ATG5 conjugate.
messages: The N-terminal region is involved in phosphatidylethanolamine-binding and is required for ATG8-PE conjugation.
messages: The flexible region (FR) is required for ATG7-binding.
messages: The handle region (HR) contains the ATG8 interaction motif (AIM) and mediates binding to ATG8. It is crucial for the cytoplasm-to-vacuole targeting pathway (By similarity).

284591:YALI0 B18260g
gene id: 284591:YALI0_B18260g
uniprot id: Q6CE63
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E10791g
gene id: 284591:YALI0_E10791g
uniprot id: Q6C6B7
names: Similarity
messages: Belongs to the MAD2 family.

284591:YALI0 C12034g
gene id: 284591:YALI0_C12034g
uniprot id: Q6CC67
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B19250g
gene id: 284591:YALI0_B19250g
uniprot id: Q6CE20
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F13959g
gene id: 284591:YALI0_F13959g
uniprot id: Q6C1S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284591:YALI0 E05643g
gene id: 284591:YALI0_E05643g
uniprot id: Q6C6W8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

284591:YALI0 C05665g
gene id: 284591:YALI0_C05665g
uniprot id: F2Z5Y1
names: Similarity
messages: Belongs to the 14-3-3 family.

284591:YALI0 F27929g
gene id: 284591:YALI0_F27929g
uniprot id: Q6C043
names: Similarity
messages: Belongs to the MGR2 family.

284591:YALI0 F20570g
gene id: 284591:YALI0_F20570g
uniprot id: Q6C0Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity).

284591:YALI0 F06402g
gene id: 284591:YALI0_F06402g
uniprot id: Q6C2N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

284591:YALI0 F18766g
gene id: 284591:YALI0_F18766g
uniprot id: Q6C169
names: PTM
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.
messages: Phosphorylated.

284591:YALI0 E22880g
gene id: 284591:YALI0_E22880g
uniprot id: Q6C4X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family.
messages: Cytoplasm
messages: Putative tyrosine-protein phosphatase required for protection against superoxide stress.

284591:YALI0 B05896g
gene id: 284591:YALI0_B05896g
uniprot id: Q6CFL3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL27 family.

284591:YALI0 E12089g
gene id: 284591:YALI0_E12089g
uniprot id: Q6C664
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 F12463g
gene id: 284591:YALI0_F12463g
uniprot id: Q6C1Y2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

284591:YALI0 B20372g
gene id: 284591:YALI0_B20372g
uniprot id: F2Z660
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

284591:YALI0 B12980g
gene id: 284591:YALI0_B12980g
uniprot id: Q6CET9
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D16665g
gene id: 284591:YALI0_D16665g
uniprot id: Q6C8V6
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

284591:YALI0 F19712g
gene id: 284591:YALI0_F19712g
uniprot id: F2Z695
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer.

284591:YALI0 C20273g
gene id: 284591:YALI0_C20273g
uniprot id: Q6CBB7
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 A17919g
gene id: 284591:YALI0_A17919g
uniprot id: Q6CGN1
names: Similarity
messages: Belongs to the PGA52 family.

284591:YALI0 C22704g
gene id: 284591:YALI0_C22704g
uniprot id: Q6CB13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat MDV1/CAF4 family.
messages: Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity).
messages: Mitochondrion outer membrane

284591:YALI0 B02838g
gene id: 284591:YALI0_B02838g
uniprot id: Q6CFX2
names: Similarity
messages: Belongs to the peptidase S9B family.

284591:YALI0 E01804g
gene id: 284591:YALI0_E01804g
uniprot id: Q6C7D1
names: Domain
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Autopalmitoylated.
messages: Belongs to the DHHC palmitoyltransferase family. PFA5 subfamily.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

284591:YALI0 F31075g
gene id: 284591:YALI0_F31075g
uniprot id: Q12726
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
messages: Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.
messages: Mitochondrion

284591:YALI0 E05863g
gene id: 284591:YALI0_E05863g
uniprot id: Q6C6V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGM101 family.
messages: Performs an essential function in the repair of oxidatively damaged mtDNA that is required for the maintenance of the mitochondrial genome. Binds to DNA (By similarity).
messages: mitochondrion nucleoid

284591:YALI0 F29337g
gene id: 284591:YALI0_F29337g
uniprot id: Q6BZZ9
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

284591:YALI0 D04785g
gene id: 284591:YALI0_D04785g
uniprot id: Q6CA95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

284591:YALI0 E11099g
gene id: 284591:YALI0_E11099g
uniprot id: Q6L8K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Essential for n-decane utilization.
messages: Peroxisome

284591:YALI0 E04092g
gene id: 284591:YALI0_E04092g
uniprot id: Q6C735
names: Similarity
messages: Belongs to the XPG/RAD2 endonuclease family.

284591:YALI0 B06963g
gene id: 284591:YALI0_B06963g
uniprot id: Q6CFH3
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

284591:YALI0 F15785g
gene id: 284591:YALI0_F15785g
uniprot id: Q6C1J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus

284591:YALI0 F16181g
gene id: 284591:YALI0_F16181g
uniprot id: Q6C1H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

284591:YALI0 F04774g
gene id: 284591:YALI0_F04774g
uniprot id: Q6C2V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase h subunit family.
messages: F-type ATP synthases have 2 components, the catalytic core F(1) and the membrane-embedded component F(0), linked together by a central stalk and a peripheral stalk (PubMed:27373333). The central stalk, also called rotor shaft, is often seen as part of F(1) (PubMed:27373333). The peripheral stalk is seen as part of F(0) (PubMed:27373333). F(0) contains the membrane channel next to the rotor (PubMed:27373333). F-type ATP synthases form dimers but each monomer functions independently in ATP generation (PubMed:27373333). The dimer consists of 17 different polypeptides: ATP1 (subunit alpha, 3 molecules per monomer, part of F(1)), ATP2 (subunit beta, 3 copies per monomer, part of F(1)), ATP3 (subunit gamma, part of the central stalk), ATP4 (subunit b, part of the peripheral stalk), ATP5/OSCP (subunit 5/OSCP, part of the peripheral stalk), ATP6 (subunit a, part of the peripheral stalk), ATP7 (subunit d, part of the peripheral stalk), ATP8 (subunit 8, part of the peripheral stalk), OLI1 (subunit c, part of the rotor, 10 molecules per monomer), ATP14 (subunit H, part of the peripheral stalk), ATP15 (subunit epsilon, part of the central stalk), ATP16 (subunit delta, part of the central stalk), ATP17 (subunit f, part of the peripheral stalk), ATP18 (subunit i/j, part of the peripheral stalk), ATP19 (subunit k, dimer-specific, at interface between monomers), ATP20 (subunit g, at interface between monomers), TIM11 (subunit e, at interface between monomers) (PubMed:27373333, PubMed:25759169).
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169). F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27373333). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (PubMed:27373333). Part of the peripheral stalk (PubMed:27373333).
messages: Mitochondrion inner membrane

284591:YALI0 D07304g
gene id: 284591:YALI0_D07304g
uniprot id: Q6C9Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

284591:YALI0 B06116g
gene id: 284591:YALI0_B06116g
uniprot id: Q6CFK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS9 family.
messages: Mitochondrion

284591:YALI0 F02365g
gene id: 284591:YALI0_F02365g
uniprot id: Q6C360
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC6 subfamily.
messages: Chromosome
messages: Nucleus

284591:YALI0 D06589g
gene id: 284591:YALI0_D06589g
uniprot id: Q6CA20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

284591:YALI0 C05368g
gene id: 284591:YALI0_C05368g
uniprot id: Q6CCZ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
messages: Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
messages: Nucleus
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

284591:YALI0 F14861g
gene id: 284591:YALI0_F14861g
uniprot id: Q6C1N0
names: Subunit
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

284591:YALI0 E05555g
gene id: 284591:YALI0_E05555g
uniprot id: Q6C6X2
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 E06721g
gene id: 284591:YALI0_E06721g
uniprot id: Q6C6S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: Endoplasmic reticulum membrane
messages: May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.

284591:YALI0 F16291g
gene id: 284591:YALI0_F16291g
uniprot id: Q6C1H2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

284591:YALI0 A02354g
gene id: 284591:YALI0_A02354g
uniprot id: Q6CI24
names: Similarity
messages: Belongs to the OSBP family.

284591:YALI0 E00880g
gene id: 284591:YALI0_E00880g
uniprot id: Q6C7H1
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F21659g
gene id: 284591:YALI0_F21659g
uniprot id: Q6C0U6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

284591:YALI0 D13970g
gene id: 284591:YALI0_D13970g
uniprot id: Q6C952
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B16368g
gene id: 284591:YALI0_B16368g
uniprot id: Q6CEE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Membrane

284591:YALI0 F09185g
gene id: 284591:YALI0_F09185g
uniprot id: P30614
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

284591:YALI0 B11374g
gene id: 284591:YALI0_B11374g
uniprot id: Q6CF05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

284591:YALI0 D06501g
gene id: 284591:YALI0_D06501g
uniprot id: Q6CA24
names: Function
names: Similarity
messages: Belongs to the HTP reductase family.
messages: Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.

284591:YALI0 B19558g
gene id: 284591:YALI0_B19558g
uniprot id: Q6CE12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with TRM82.
messages: Nucleus

284591:YALI0 E14102g
gene id: 284591:YALI0_E14102g
uniprot id: Q6C5Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

284591:YALI0 D14410g
gene id: 284591:YALI0_D14410g
uniprot id: Q6C942
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

284591:YALI0 E11077g
gene id: 284591:YALI0_E11077g
uniprot id: Q6C6A5
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.

284591:YALI0 A03905g
gene id: 284591:YALI0_A03905g
uniprot id: Q6CHX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

284591:YALI0 A14212g
gene id: 284591:YALI0_A14212g
uniprot id: Q6CH11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 B13728g
gene id: 284591:YALI0_B13728g
uniprot id: Q6CER1
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

284591:YALI0 F17248g
gene id: 284591:YALI0_F17248g
uniprot id: F2Z626
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

284591:YALI0 E16060g
gene id: 284591:YALI0_E16060g
uniprot id: Q6C5Q6
names: Similarity
messages: Belongs to the lysophospholipase family.

284591:YALI0 E28153g
gene id: 284591:YALI0_E28153g
uniprot id: Q6C4B9
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

284591:YALI0 B06754g
gene id: 284591:YALI0_B06754g
uniprot id: Q6CFI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDI1 family.
messages: Binds ubiquitin and polyubiquitinated proteins.
messages: Cytoplasm
messages: Probable aspartic protease. May be involved in the regulation of exocytosis. Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation. Required for S-phase checkpoint control.

284591:YALI0 F27247g
gene id: 284591:YALI0_F27247g
uniprot id: Q6C074
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

284591:YALI0 D12859g
gene id: 284591:YALI0_D12859g
uniprot id: Q6C998
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

284591:YALI0 B17644g
gene id: 284591:YALI0_B17644g
uniprot id: Q6CE88
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.
messages: Responsible for the reduction of the keto group on the C-3 of sterols.

284591:YALI0 E26389g
gene id: 284591:YALI0_E26389g
uniprot id: Q6C4I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. The complex is held together by ERB1, which interacts with NOP7 via its N-terminal domain and with YTM1 via a high-affinity interaction between the seven-bladed beta-propeller domains of the 2 proteins. The NOP7 complex associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

284591:YALI0 F28831g
gene id: 284591:YALI0_F28831g
uniprot id: Q6C008
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 A03927g
gene id: 284591:YALI0_A03927g
uniprot id: Q6CHW9
names: Similarity
messages: Belongs to the helicase family.

284591:YALI0 F28039g
gene id: 284591:YALI0_F28039g
uniprot id: Q6C038
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

284591:YALI0 E01496g
gene id: 284591:YALI0_E01496g
uniprot id: Q6C7E4
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

284591:YALI0 C01716g
gene id: 284591:YALI0_C01716g
uniprot id: Q6CDC5
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

284591:YALI0 A18337g
gene id: 284591:YALI0_A18337g
uniprot id: Q6CGL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
messages: Cytoplasm
messages: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates. Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins. Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo.
messages: Nucleus

284591:YALI0 F23595g
gene id: 284591:YALI0_F23595g
uniprot id: Q6C0L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
messages: Belongs to the peptidase S16 family.
messages: Peroxisome matrix

284591:YALI0 E28875g
gene id: 284591:YALI0_E28875g
uniprot id: Q6C486
names: Similarity
messages: Belongs to the peptidase S8 family.

284591:YALI0 F17710g
gene id: 284591:YALI0_F17710g
uniprot id: Q6C1B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Required for vacuolar assembly and vacuolar traffic.
messages: Vacuole

284591:YALI0 C24277g
gene id: 284591:YALI0_C24277g
uniprot id: Q6CAU4
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

284591:YALI0 C16973g
gene id: 284591:YALI0_C16973g
uniprot id: Q6CBN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVF1 family.
messages: Cytoplasm
messages: May be involved in the response to oxidative stress.
messages: Nucleus

284591:YALI0 F11649g
gene id: 284591:YALI0_F11649g
uniprot id: Q6C216
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly (By similarity).

284591:YALI0 D21120g
gene id: 284591:YALI0_D21120g
uniprot id: Q6C8B2
names: Similarity
messages: Belongs to the peptidase C48 family.

284591:YALI0 F24739g
gene id: 284591:YALI0_F24739g
uniprot id: Q6C0H1
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

284591:YALI0 C20405g
gene id: 284591:YALI0_C20405g
uniprot id: Q6CBB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasm
messages: Serine hydrolase involved in the detoxification of formaldehyde.

284591:YALI0 E04356g
gene id: 284591:YALI0_E04356g
uniprot id: Q6C725
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMN1 family.
messages: Cytoplasm
messages: Negative regulator of the mitotic exit network (MEN), required for multiple cell cycle checkpoints. Required for daughter cell separation and chromosome stability. Involved in copper sensitivity.
messages: Nucleus

284591:YALI0 F18238g
gene id: 284591:YALI0_F18238g
uniprot id: Q6C193
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits. Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5.8S rRNAs through the processing of pre-rRNAs at sites C1 and C2 (By similarity).
messages: Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284591:YALI0 E11803g
gene id: 284591:YALI0_E11803g
uniprot id: Q6C678
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

284591:YALI0 E22979g
gene id: 284591:YALI0_E22979g
uniprot id: Q6C4X4
names: Similarity
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Tetramer of two alpha and two beta subunits.

284591:YALI0 B14707g
gene id: 284591:YALI0_B14707g
uniprot id: Q6CEL6
names: Similarity
messages: Belongs to the MIP18 family.

284591:YALI0 C06083g
gene id: 284591:YALI0_C06083g
uniprot id: Q6CCW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.
messages: Homodimer.
messages: Mitochondrion matrix

284591:YALI0 F07084g
gene id: 284591:YALI0_F07084g
uniprot id: Q6C2K6
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

284591:YALI0 D19866g
gene id: 284591:YALI0_D19866g
uniprot id: Q6C8G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

284591:YALI0 C03025g
gene id: 284591:YALI0_C03025g
uniprot id: Q6CD79
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

284591:YALI0 B18759g
gene id: 284591:YALI0_B18759g
uniprot id: Q6CE40
names: Function
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.
messages: Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP.

284591:YALI0 C19668g
gene id: 284591:YALI0_C19668g
uniprot id: Q6CBE2
names: Similarity
messages: Belongs to the WrbA family.

284591:YALI0 A15972g
gene id: 284591:YALI0_A15972g
uniprot id: Q6CGV1
names: Similarity
messages: Belongs to the FBPase class 1 family.

284591:YALI0 C10967g
gene id: 284591:YALI0_C10967g
uniprot id: Q6CCB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
messages: Component of the srb8-11 complex, a regulatory module of the Mediator complex.
messages: Component of the srb8-11 complex. The srb8-11 complex is a regulatory module of the Mediator complex which is itself dependent transcription. The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The srb8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity).
messages: Nucleus

284591:YALI0 B21010g
gene id: 284591:YALI0_B21010g
uniprot id: Q6CDV0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F00418g
gene id: 284591:YALI0_F00418g
uniprot id: Q6C3E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284591:YALI0 F19690g
gene id: 284591:YALI0_F19690g
uniprot id: Q6C130
names: Similarity
messages: Belongs to the SAP30 family.

284591:YALI0 F01430g
gene id: 284591:YALI0_F01430g
uniprot id: Q6C3A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 E15994g
gene id: 284591:YALI0_E15994g
uniprot id: Q6C5Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COPE family.
messages: Cytoplasm
messages: Membrane

284591:YALI0 C05104g
gene id: 284591:YALI0_C05104g
uniprot id: Q6CD01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

284591:YALI0 F16467g
gene id: 284591:YALI0_F16467g
uniprot id: Q6C1G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.
messages: Belongs to the COG6 family.
messages: Component of the conserved oligomeric Golgi complex.
messages: Golgi apparatus membrane
messages: Membrane

284591:YALI0 E21417g
gene id: 284591:YALI0_E21417g
uniprot id: Q6C533
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 C21868g
gene id: 284591:YALI0_C21868g
uniprot id: Q6CB52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
messages: May form heterododecamers with RVB2. Component of the SWR1 chromatin remodeling complex, the INO80 chromatin remodeling complex, and of the R2TP complex (By similarity).
messages: Nucleus

284591:YALI0 B08712g
gene id: 284591:YALI0_B08712g
uniprot id: Q6CFB2
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E05753g
gene id: 284591:YALI0_E05753g
uniprot id: Q6C6W3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

284591:YALI0 D10043g
gene id: 284591:YALI0_D10043g
uniprot id: Q6C9M0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E24167g
gene id: 284591:YALI0_E24167g
uniprot id: Q6C4S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

284591:YALI0 E30965g
gene id: 284591:YALI0_E30965g
uniprot id: Q6C3Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Cytoplasm
messages: Presumably involved in regulating the intracellular acetyl-CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.

284591:YALI0 D06281g
gene id: 284591:YALI0_D06281g
uniprot id: Q6CA34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.

284591:YALI0 F07865g
gene id: 284591:YALI0_F07865g
uniprot id: Q6C2H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fungal TPase family.
messages: First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.
messages: Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.
messages: Nucleus

284591:YALI0 E28358g
gene id: 284591:YALI0_E28358g
uniprot id: Q6C4A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

284591:YALI0 A01375g
gene id: 284591:YALI0_A01375g
uniprot id: Q6CI62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ASF1 family.
messages: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
messages: Interacts with histone H3 and histone H4.
messages: Nucleus

284591:YALI0 D25454g
gene id: 284591:YALI0_D25454g
uniprot id: Q6C7T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Membrane

284591:YALI0 D09713g
gene id: 284591:YALI0_D09713g
uniprot id: Q6C9N5
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

284591:YALI0 B21868g
gene id: 284591:YALI0_B21868g
uniprot id: Q6CDR4
names: Similarity
messages: Belongs to the TTC36 family.

284591:YALI0 B12628g
gene id: 284591:YALI0_B12628g
uniprot id: Q6CEV3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

284591:YALI0 F15631g
gene id: 284591:YALI0_F15631g
uniprot id: Q6C1K0
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

284591:YALI0 D15972g
gene id: 284591:YALI0_D15972g
uniprot id: Q6C8Y0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E21626g
gene id: 284591:YALI0_E21626g
uniprot id: Q6C525
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

284591:YALI0 D19162g
gene id: 284591:YALI0_D19162g
uniprot id: Q9UVF5
names: Function
names: Similarity
messages: Belongs to the arrestin family. PalF/RIM8 subfamily.
messages: Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.

284591:YALI0 E20471g
gene id: 284591:YALI0_E20471g
uniprot id: Q6C574
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D07920g
gene id: 284591:YALI0_D07920g
uniprot id: Q6C9V8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homodimer.
messages: Mitochondrion
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

284591:YALI0 E20163g
gene id: 284591:YALI0_E20163g
uniprot id: Q6C586
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

284591:YALI0 C02409g
gene id: 284591:YALI0_C02409g
uniprot id: Q6CDA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

284591:YALI0 A17468g
gene id: 284591:YALI0_A17468g
uniprot id: Q6CGP7
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 C00759g
gene id: 284591:YALI0_C00759g
uniprot id: Q6CDG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal Na(+)/H(+) exchanger family.
messages: Membrane

284591:YALI0 A19558g
gene id: 284591:YALI0_A19558g
uniprot id: Q6CGG5
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B10846g
gene id: 284591:YALI0_B10846g
uniprot id: Q6CF26
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B17776g
gene id: 284591:YALI0_B17776g
uniprot id: Q6CE82
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E18238g
gene id: 284591:YALI0_E18238g
uniprot id: Q6C5G6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

284591:YALI0 F20966g
gene id: 284591:YALI0_F20966g
uniprot id: Q6C0X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284591:YALI0 F11231g
gene id: 284591:YALI0_F11231g
uniprot id: Q6C234
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

284591:YALI0 C12661g
gene id: 284591:YALI0_C12661g
uniprot id: Q6CC41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

284591:YALI0 C15807g
gene id: 284591:YALI0_C15807g
uniprot id: Q6CBT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

284591:YALI0 E10065g
gene id: 284591:YALI0_E10065g
uniprot id: Q6C6F0
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

284591:YALI0 E15598g
gene id: 284591:YALI0_E15598g
uniprot id: Q6C5S4
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

284591:YALI0 F18392g
gene id: 284591:YALI0_F18392g
uniprot id: Q6C186
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the crooked-neck family.
messages: Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication (By similarity).
messages: Nucleus

284591:YALI0 F21615g
gene id: 284591:YALI0_F21615g
uniprot id: Q6C0U8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family. PreP subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Degrades mitochondrial transit peptides after their cleavage in the intermembrane space or in the matrix, and presequence peptides; clearance of these peptides is required to keep the presequence processing machinery running (By similarity). Preferentially cleaves the N-terminal side of paired basic amino acid residues (By similarity). Also degrades other unstructured peptides (By similarity). May function as an ATP-dependent peptidase as opposed to a metalloendopeptidase (By similarity).
messages: Mitochondrion intermembrane space
messages: Mitochondrion matrix
messages: Monomer and homodimer; homodimerization is induced by binding of the substrate.

284591:YALI0 B02398g
gene id: 284591:YALI0_B02398g
uniprot id: Q6CFY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284591:YALI0 D11704g
gene id: 284591:YALI0_D11704g
uniprot id: Q6C9F1
names: Similarity
messages: Belongs to the aspartokinase family.

284591:YALI0 E01672g
gene id: 284591:YALI0_E01672g
uniprot id: Q6C7D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP25 family.
messages: Mitochondrion inner membrane
messages: Probable mitochondrial mRNA stabilization factor.

284591:YALI0 F06248g
gene id: 284591:YALI0_F06248g
uniprot id: Q6C2P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: High-conductance magnesium-selective channel that mediates the influx of magnesium into the mitochondrial matrix. Essential for the splicing of mRNA group II introns in mitochondria by affecting mitochondrial magnesium concentrations, which are critical for group II intron splicing. It also suppresses a variety of mitochondrial intron mutations and its absence may disturb the assembly of mitochondrial membrane complexes.
messages: Homopentamer. Forms homooligomers. Interacts with MFM1.
messages: Mitochondrion inner membrane

284591:YALI0 B12056g
gene id: 284591:YALI0_B12056g
uniprot id: Q6CEX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

284591:YALI0 E02684g
gene id: 284591:YALI0_E02684g
uniprot id: Q6C793
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activity is inhibited by p-chloromercuribenzoate (pCMB), monoiodoacetamide, H(2)O(2), ATP, ADP, NADH, NADPH, Hg(2+) and Zn(2+).
messages: Belongs to the citrate synthase family.
messages: Component of the methylcitrate cycle that catalyzes the synthesis of (2S,3S)-2-methylcitrate from propionyl-CoA and oxaloacetate. Plays an important role in detoxification of propionyl-CoA, an inhibitor of both primary and secondary metabolism. Has also citrate synthase activity using as substrates acetyl-CoA and oxaloacetate.
messages: Homodimer.
messages: Mitochondrion matrix

284591:YALI0 F17028g
gene id: 284591:YALI0_F17028g
uniprot id: Q6C1E4
names: Function
names: Similarity
messages: Belongs to the palC family.
messages: Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.

284591:YALI0 A11605g
gene id: 284591:YALI0_A11605g
uniprot id: Q6CH77
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B19206g
gene id: 284591:YALI0_B19206g
uniprot id: Q6CE22
names: Similarity
messages: Belongs to the cyclin family.

284591:YALI0 B00836g
gene id: 284591:YALI0_B00836g
uniprot id: Q6CG51
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

284591:YALI0 C21450g
gene id: 284591:YALI0_C21450g
uniprot id: Q6CB70
names: Similarity
messages: Belongs to the MEMO1 family.

284591:YALI0 E22781g
gene id: 284591:YALI0_E22781g
uniprot id: Q6C4Y2
names: Similarity
messages: Belongs to the OSBP family.

284591:YALI0 F07062g
gene id: 284591:YALI0_F07062g
uniprot id: Q6C2K7
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B09537g
gene id: 284591:YALI0_B09537g
uniprot id: Q6CF79
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F16489g
gene id: 284591:YALI0_F16489g
uniprot id: Q6C1G4
names: Similarity
messages: Belongs to the peptidase M20A family.

284591:YALI0 C22484g
gene id: 284591:YALI0_C22484g
uniprot id: Q6CB23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC24 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284591:YALI0 F17512g
gene id: 284591:YALI0_F17512g
uniprot id: Q6C1C3
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

284591:YALI0 D11198g
gene id: 284591:YALI0_D11198g
uniprot id: Q6C9H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

284591:YALI0 E21505g
gene id: 284591:YALI0_E21505g
uniprot id: Q6C531
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YAE1 family.
messages: Cytoplasm
messages: May form a complex with LTO1.
messages: Nucleus
messages: The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery. May be required for biogenesis of the large ribosomal subunit and initiation of translation.

284591:YALI0 D19844g
gene id: 284591:YALI0_D19844g
uniprot id: Q6C8G6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: cytoskeleton

284591:YALI0 D00869g
gene id: 284591:YALI0_D00869g
uniprot id: Q6CAQ2
names: Similarity
messages: Belongs to the amidase family.

284591:YALI0 F18964g
gene id: 284591:YALI0_F18964g
uniprot id: Q6C160
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284591:YALI0 E08448g
gene id: 284591:YALI0_E08448g
uniprot id: Q6C6L7
names: Similarity
messages: Belongs to the LTV1 family.

284591:YALI0 E15312g
gene id: 284591:YALI0_E15312g
uniprot id: Q6C5T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

284591:YALI0 D12793g
gene id: 284591:YALI0_D12793g
uniprot id: Q6C9A1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

284591:YALI0 E27962g
gene id: 284591:YALI0_E27962g
uniprot id: Q6C4C2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

284591:YALI0 B14058g
gene id: 284591:YALI0_B14058g
uniprot id: Q6CEP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

284591:YALI0 C23683g
gene id: 284591:YALI0_C23683g
uniprot id: Q6CAX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC26 family.
messages: Cytoplasm
messages: Involved in pre-mRNA splicing.
messages: Nucleus

284591:YALI0 D14762g
gene id: 284591:YALI0_D14762g
uniprot id: Q6C928
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
messages: Heterodimer of an alpha and a beta subunit.

284591:YALI0 F04378g
gene id: 284591:YALI0_F04378g
uniprot id: Q6C2X2
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

284591:YALI0 E22671g
gene id: 284591:YALI0_E22671g
uniprot id: Q6C4Y6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

284591:YALI0 B13046g
gene id: 284591:YALI0_B13046g
uniprot id: Q6CET8
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F24893g
gene id: 284591:YALI0_F24893g
uniprot id: Q6C0G7
names: Similarity
messages: In the C-terminal section; belongs to the TrpB family.
messages: In the N-terminal section; belongs to the TrpA family.

284591:YALI0 E05665g
gene id: 284591:YALI0_E05665g
uniprot id: Q6C6W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

284591:YALI0 B15180g
gene id: 284591:YALI0_B15180g
uniprot id: Q6CEJ4
names: Similarity
messages: Belongs to the cyclin family.

284591:YALI0 B13112g
gene id: 284591:YALI0_B13112g
uniprot id: Q6CET5
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D11176g
gene id: 284591:YALI0_D11176g
uniprot id: Q6C9H5
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

284591:YALI0 E15620g
gene id: 284591:YALI0_E15620g
uniprot id: Q6C5S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Nucleus

284591:YALI0 C23408g
gene id: 284591:YALI0_C23408g
uniprot id: Q6CAY2
names: Similarity
messages: Belongs to the IlvD/Edd family.

284591:YALI0 B00374g
gene id: 284591:YALI0_B00374g
uniprot id: Q6CG70
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 D17534g
gene id: 284591:YALI0_D17534g
uniprot id: Q6C8R8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

284591:YALI0 E21934g
gene id: 284591:YALI0_E21934g
uniprot id: Q6C513
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

284591:YALI0 C22550g
gene id: 284591:YALI0_C22550g
uniprot id: Q6CB20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

284591:YALI0 E17919g
gene id: 284591:YALI0_E17919g
uniprot id: Q6C5H9
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

284591:YALI0 E09405g
gene id: 284591:YALI0_E09405g
uniprot id: Q6C6H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the peroxisomal translocation machinery.
messages: Peroxisome membrane

284591:YALI0 B17292g
gene id: 284591:YALI0_B17292g
uniprot id: Q6CEA2
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B10714g
gene id: 284591:YALI0_B10714g
uniprot id: Q6CF31
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A00110g
gene id: 284591:YALI0_A00110g
uniprot id: Q6CIA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284591:YALI0 F17402g
gene id: 284591:YALI0_F17402g
uniprot id: Q6C1C8
names: Similarity
messages: Belongs to the glycosyltransferase 34 family.

284591:YALI0 E18414g
gene id: 284591:YALI0_E18414g
uniprot id: Q6C5G0
names: Similarity
messages: Belongs to the SNAP-25 family.

284591:YALI0 F15609g
gene id: 284591:YALI0_F15609g
uniprot id: Q6C1K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

284591:YALI0 B01738g
gene id: 284591:YALI0_B01738g
uniprot id: Q6CG14
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 F04312g
gene id: 284591:YALI0_F04312g
uniprot id: Q6C2X5
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F27533g
gene id: 284591:YALI0_F27533g
uniprot id: Q6C061
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP4 subfamily.
messages: Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (By similarity).
messages: Component of the NuA4 histone acetyltransferase complex, of the INO80 chromatin remodeling complex, and of the SWR1 chromatin remodeling complex.
messages: Nucleus

284591:YALI0 D09119g
gene id: 284591:YALI0_D09119g
uniprot id: Q6C9Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

284591:YALI0 C14586g
gene id: 284591:YALI0_C14586g
uniprot id: Q6CBX8
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

284591:YALI0 D16775g
gene id: 284591:YALI0_D16775g
uniprot id: Q6C8V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM18/AIM46 family.
messages: Mitochondrion

284591:YALI0 B08756g
gene id: 284591:YALI0_B08756g
uniprot id: Q6CFA9
names: Subcellular Location Annotation
messages: nucleolus

284591:YALI0 F24299g
gene id: 284591:YALI0_F24299g
uniprot id: Q6C0I9
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B20482g
gene id: 284591:YALI0_B20482g
uniprot id: Q6CDX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

284591:YALI0 B06105g
gene id: 284591:YALI0_B06105g
uniprot id: B5FVB2
names: Similarity
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.

284591:YALI0 D02585g
gene id: 284591:YALI0_D02585g
uniprot id: Q6CAI1
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E28371g
gene id: 284591:YALI0_E28371g
uniprot id: Q6C4A8
names: Similarity
messages: Belongs to the TOG/XMAP215 family.

284591:YALI0 D09042g
gene id: 284591:YALI0_D09042g
uniprot id: Q6C9R1
names: Similarity
messages: Belongs to the peptidase S10 family.

284591:YALI0 C03465g
gene id: 284591:YALI0_C03465g
uniprot id: Q6CD63
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

284591:YALI0 D22638g
gene id: 284591:YALI0_D22638g
uniprot id: Q6C852
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E03234g
gene id: 284591:YALI0_E03234g
uniprot id: Q6C772
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

284591:YALI0 D18403g
gene id: 284591:YALI0_D18403g
uniprot id: Q6C8M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Cytoplasm
messages: Membrane
messages: Probable sterol 3-beta-glucosyltransferase that is not involved in cytoplasm to vacuole transport (Cvt), pexophagy or nonselective autophagy (By similarity).

284591:YALI0 C03355g
gene id: 284591:YALI0_C03355g
uniprot id: Q6CD68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.

284591:YALI0 F18436g
gene id: 284591:YALI0_F18436g
uniprot id: Q6C184
names: Similarity
messages: Belongs to the dopey family.

284591:YALI0 A00825g
gene id: 284591:YALI0_A00825g
uniprot id: Q6CI81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTC4 family.
messages: May be involved in a process influencing telomere capping.
messages: Nucleus

284591:YALI0 E26059g
gene id: 284591:YALI0_E26059g
uniprot id: Q6C4K2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

284591:YALI0 B15774g
gene id: 284591:YALI0_B15774g
uniprot id: Q6CEG7
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

284591:YALI0 F23463g
gene id: 284591:YALI0_F23463g
uniprot id: Q6C0M3
names: Function
names: Similarity
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.

284591:YALI0 D12144g
gene id: 284591:YALI0_D12144g
uniprot id: Q6C9D2
names: Subcellular Location Annotation
messages: Cytoplasm

284591:YALI0 D17974g
gene id: 284591:YALI0_D17974g
uniprot id: Q6C8P9
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A10310g
gene id: 284591:YALI0_A10310g
uniprot id: Q6CHC2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

284591:YALI0 F16115g
gene id: 284591:YALI0_F16115g
uniprot id: Q6C1H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

284591:YALI0 A03003g
gene id: 284591:YALI0_A03003g
uniprot id: Q6CHZ8
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

284591:YALI0 A21417g
gene id: 284591:YALI0_A21417g
uniprot id: Q6CG81
names: Similarity
messages: Belongs to the threonine aldolase family.

284591:YALI0 B08514g
gene id: 284591:YALI0_B08514g
uniprot id: Q6CFB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: Cytoplasm

284591:YALI0 D24343g
gene id: 284591:YALI0_D24343g
uniprot id: Q6C7Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM54 family.
messages: Component of the TIM22 complex, whose core is composed of TIM22 and TIM54, associated with the 70 kDa heterohexamer composed of TIM9 and TIM10 (or TIM8 and TIM13).
messages: Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
messages: Mitochondrion inner membrane

284591:YALI0 D05511g
gene id: 284591:YALI0_D05511g
uniprot id: Q6CA66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

284591:YALI0 F14223g
gene id: 284591:YALI0_F14223g
uniprot id: Q6C1Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 E14234g
gene id: 284591:YALI0_E14234g
uniprot id: Q6C5X7
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A19008g
gene id: 284591:YALI0_A19008g
uniprot id: Q6CGI6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C05621g
gene id: 284591:YALI0_C05621g
uniprot id: Q6CCY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase inhibitor family.
messages: Forms a one-to-one complex with ATPase to inhibit the enzyme activity completely.
messages: Mitochondrion

284591:YALI0 C06490g
gene id: 284591:YALI0_C06490g
uniprot id: Q6CCU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint (By similarity).

284591:YALI0 E34170g
gene id: 284591:YALI0_E34170g
uniprot id: Q6C3K0
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

284591:YALI0 D18920g
gene id: 284591:YALI0_D18920g
uniprot id: Q6C8K4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Membrane
messages: Mitochondrion inner membrane

284591:YALI0 D24079g
gene id: 284591:YALI0_D24079g
uniprot id: Q6C7Z6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

284591:YALI0 F26587g
gene id: 284591:YALI0_F26587g
uniprot id: Q6C098
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

284591:YALI0 B22572g
gene id: 284591:YALI0_B22572g
uniprot id: Q6CDN5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Associated with pre-ribosomal particles.
messages: Belongs to the DEAD box helicase family. DDX51/DBP6 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284591:YALI0 A04741g
gene id: 284591:YALI0_A04741g
uniprot id: Q6CHU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

284591:YALI0 D11506g
gene id: 284591:YALI0_D11506g
uniprot id: Q6C9G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIR3 family.
messages: Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation.
messages: Nucleus

284591:YALI0 D18271g
gene id: 284591:YALI0_D18271g
uniprot id: Q6C8N4
names: Similarity
messages: Belongs to the cytidylyltransferase family.

284591:YALI0 E15796g
gene id: 284591:YALI0_E15796g
uniprot id: Q6C5R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

284591:YALI0 F29073g
gene id: 284591:YALI0_F29073g
uniprot id: Q6C007
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the RRM CWC2 family.
messages: Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle (By similarity).
messages: Nucleus
messages: The C-terminal RRM domain and the zinc finger motif are necessary for RNA-binding.

284591:YALI0 E14146g
gene id: 284591:YALI0_E14146g
uniprot id: Q6C5Y1
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D09295g
gene id: 284591:YALI0_D09295g
uniprot id: Q6C9P9
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D23881g
gene id: 284591:YALI0_D23881g
uniprot id: Q6C803
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

284591:YALI0 E20669g
gene id: 284591:YALI0_E20669g
uniprot id: Q6C565
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily.

284591:YALI0 A11539g
gene id: 284591:YALI0_A11539g
uniprot id: Q6CH79
names: Similarity
messages: Belongs to the helicase family.

284591:YALI0 B13552g
gene id: 284591:YALI0_B13552g
uniprot id: Q6CER7
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

284591:YALI0 D09669g
gene id: 284591:YALI0_D09669g
uniprot id: Q6C9N7
names: Similarity
messages: Belongs to the helicase family.

284591:YALI0 B03388g
gene id: 284591:YALI0_B03388g
uniprot id: Q6CFV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat ASA1 family.
messages: Component of the ASTRA chromatin remodeling machinery complex.
messages: Component of the ASTRA complex involved in chromatin remodeling.
messages: Nucleus

284591:YALI0 B14223g
gene id: 284591:YALI0_B14223g
uniprot id: Q6CEN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

284591:YALI0 F16423g
gene id: 284591:YALI0_F16423g
uniprot id: Q6C1G6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 B08965g
gene id: 284591:YALI0_B08965g
uniprot id: Q6CF99
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

284591:YALI0 E17765g
gene id: 284591:YALI0_E17765g
uniprot id: Q6C5I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

284591:YALI0 E20031g
gene id: 284591:YALI0_E20031g
uniprot id: Q6C592
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

284591:YALI0 E13420g
gene id: 284591:YALI0_E13420g
uniprot id: Q6C612
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

284591:YALI0 E06193g
gene id: 284591:YALI0_E06193g
uniprot id: Q6C6U3
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

284591:YALI0 D25740g
gene id: 284591:YALI0_D25740g
uniprot id: Q6C7S5
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

284591:YALI0 F18502g
gene id: 284591:YALI0_F18502g
uniprot id: Q6C181
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

284591:YALI0 F25091g
gene id: 284591:YALI0_F25091g
uniprot id: Q6C0F8
names: Similarity
messages: Belongs to the peptidase M16 family.

284591:YALI0 E05929g
gene id: 284591:YALI0_E05929g
uniprot id: Q6C6V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

284591:YALI0 F09229g
gene id: 284591:YALI0_F09229g
uniprot id: Q6C2B5
names: Similarity
messages: Belongs to the NDK family.

284591:YALI0 D06754g
gene id: 284591:YALI0_D06754g
uniprot id: Q6CA12
names: Similarity
messages: Belongs to the multicopper oxidase family.

284591:YALI0 D06578g
gene id: 284591:YALI0_D06578g
uniprot id: B5FVE1
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

284591:YALI0 F27071g
gene id: 284591:YALI0_F27071g
uniprot id: Q6C080
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 D08734g
gene id: 284591:YALI0_D08734g
uniprot id: Q6C9S5
names: Similarity
messages: Belongs to the SPT2 family.

284591:YALI0 B02970g
gene id: 284591:YALI0_B02970g
uniprot id: Q6CFW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX9 family.
messages: Interacts with the 35S, 23S and 20S pre-rRNAs and with the U3 snoRNA.
messages: Involved in ribosome biogenesis. Required for normal pre-rRNA processing in internal transcribed spacer 1 (ITS1). May be involved in the movements of the replication forks.
messages: nucleolus

284591:YALI0 D22935g
gene id: 284591:YALI0_D22935g
uniprot id: Q6C842
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
messages: Nucleus
messages: Serine/threonine-protein kinase involved in transcription regulation. Phosphorylates the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes. Also required for histone H3 methylation. Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase (By similarity).

284591:YALI0 B04070g
gene id: 284591:YALI0_B04070g
uniprot id: Q6CFT4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS27 family.
messages: Both IUM domains are necessary for efficient binding to ubiquitin.
messages: Component of the ESCRT-0 complex composed of HSE1 and VPS27.
messages: Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
messages: Endosome membrane
messages: The FYVE domain is involved in the binding to phosphatidylinositol 3-phosphate (PtdIns(3)P) which is required for the association to endosomal membranes.

284591:YALI0 D22132g
gene id: 284591:YALI0_D22132g
uniprot id: Q6C872
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETT1 family.
messages: Nucleus
messages: Required for correct translation termination and probably involved in regulation of hypoxic gene expression.

284591:YALI0 E13442g
gene id: 284591:YALI0_E13442g
uniprot id: Q6C611
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

284591:YALI0 F23815g
gene id: 284591:YALI0_F23815g
uniprot id: Q6C0K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BYE1 family.
messages: Negative regulator of transcription elongation.
messages: Nucleus

284591:YALI0 F12617g
gene id: 284591:YALI0_F12617g
uniprot id: Q6C1X6
names: Similarity
messages: Belongs to the PP2C family.

284591:YALI0 E29667g
gene id: 284591:YALI0_E29667g
uniprot id: Q6C450
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b560 family.
messages: Membrane

284591:YALI0 F01628g
gene id: 284591:YALI0_F01628g
uniprot id: Q6C393
names: Similarity
messages: Belongs to the LacAB/RpiB family.

284591:YALI0 E24629g
gene id: 284591:YALI0_E24629g
uniprot id: Q6C4Q1
names: Subcellular Location Annotation
messages: Cytoplasm

284591:YALI0 D26664g
gene id: 284591:YALI0_D26664g
uniprot id: Q6C7N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

284591:YALI0 F03597g
gene id: 284591:YALI0_F03597g
uniprot id: Q6C307
names: Similarity
messages: Belongs to the IUNH family.

284591:YALI0 E06765g
gene id: 284591:YALI0_E06765g
uniprot id: Q6C6S1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

284591:YALI0 F20878g
gene id: 284591:YALI0_F20878g
uniprot id: Q6C0X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

284591:YALI0 E29271g
gene id: 284591:YALI0_E29271g
uniprot id: Q6C469
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 F02695g
gene id: 284591:YALI0_F02695g
uniprot id: Q6C347
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity).
messages: Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284591:YALI0 F04191g
gene id: 284591:YALI0_F04191g
uniprot id: Q6C2X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LU7TM family.
messages: Membrane

284591:YALI0 F30679g
gene id: 284591:YALI0_F30679g
uniprot id: Q6BZV1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

284591:YALI0 E23177g
gene id: 284591:YALI0_E23177g
uniprot id: Q6C4W5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. PFA3 subfamily.
messages: Palmitoyltransferase specific for VAC8. Palmitoylates VAC8 at one or more of its N-terminal cysteine residues, which is required for its proper membrane localization (By similarity).
messages: The DHHC domain is required for palmitoyltransferase activity.
messages: Vacuole membrane

284591:YALI0 E02618g
gene id: 284591:YALI0_E02618g
uniprot id: Q6C796
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

284591:YALI0 F07260g
gene id: 284591:YALI0_F07260g
uniprot id: F2Z6C7
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

284591:YALI0 C07260g
gene id: 284591:YALI0_C07260g
uniprot id: Q6CCR3
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

284591:YALI0 C23661g
gene id: 284591:YALI0_C23661g
uniprot id: Q6CAX2
names: Similarity
messages: Belongs to the peptidase S10 family.

284591:YALI0 C21648g
gene id: 284591:YALI0_C21648g
uniprot id: Q6CB61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

284591:YALI0 F28083g
gene id: 284591:YALI0_F28083g
uniprot id: Q6C036
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

284591:YALI0 E03894g
gene id: 284591:YALI0_E03894g
uniprot id: Q6C744
names: Function
names: Similarity
messages: Belongs to the R-transferase family.
messages: Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.

284591:YALI0 A21010g
gene id: 284591:YALI0_A21010g
uniprot id: Q6CG99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 E14619g
gene id: 284591:YALI0_E14619g
uniprot id: Q6C5W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis.
messages: Nucleus

284591:YALI0 E13167g
gene id: 284591:YALI0_E13167g
uniprot id: Q6C622
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 D00605g
gene id: 284591:YALI0_D00605g
uniprot id: Q6CAR4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

284591:YALI0 F27335g
gene id: 284591:YALI0_F27335g
uniprot id: Q6C070
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DASH complex SPC19 family.
messages: Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
messages: Nucleus
messages: The DASH complex oligomerizes to form rings that encircle the microtubules.
messages: kinetochore
messages: spindle

284591:YALI0 C24233g
gene id: 284591:YALI0_C24233g
uniprot id: Q6CAU6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. MetX family.

284591:YALI0 C06644g
gene id: 284591:YALI0_C06644g
uniprot id: Q6CCT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

284591:YALI0 B14245g
gene id: 284591:YALI0_B14245g
uniprot id: Q6CEN7
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

284591:YALI0 D03113g
gene id: 284591:YALI0_D03113g
uniprot id: Q6CAF9
names: Similarity
messages: Belongs to the COG4 family.

284591:YALI0 A08734g
gene id: 284591:YALI0_A08734g
uniprot id: Q6CHH7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

284591:YALI0 D23573g
gene id: 284591:YALI0_D23573g
uniprot id: Q6C817
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

284591:YALI0 E24497g
gene id: 284591:YALI0_E24497g
uniprot id: Q6C4Q7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion matrix

284591:YALI0 E02816g
gene id: 284591:YALI0_E02816g
uniprot id: Q6C787
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

284591:YALI0 C21846g
gene id: 284591:YALI0_C21846g
uniprot id: Q6CB53
names: Subcellular Location Annotation
messages: nucleolus

284591:YALI0 F07018g
gene id: 284591:YALI0_F07018g
uniprot id: Q6C2K9
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F18348g
gene id: 284591:YALI0_F18348g
uniprot id: Q6C188
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferric reductase (FRE) family. AIM14 subfamily.
messages: Membrane
messages: Probable cell surface metalloreductase. May be involved in iron or copper homeostasis (By similarity).

284591:YALI0 E03036g
gene id: 284591:YALI0_E03036g
uniprot id: Q6C781
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer.

284591:YALI0 B18898g
gene id: 284591:YALI0_B18898g
uniprot id: Q6CE35
names: Function
names: Similarity
messages: Belongs to the PanB family.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.

284591:YALI0 D15422g
gene id: 284591:YALI0_D15422g
uniprot id: Q6C902
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E13079g
gene id: 284591:YALI0_E13079g
uniprot id: Q6C626
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus

284591:YALI0 E15268g
gene id: 284591:YALI0_E15268g
uniprot id: Q6C5T7
names: Similarity
messages: Belongs to the frataxin family.

284591:YALI0 C06303g
gene id: 284591:YALI0_C06303g
uniprot id: Q6CCV0
names: Similarity
messages: Belongs to the cytidylyltransferase family.

284591:YALI0 E28600g
gene id: 284591:YALI0_E28600g
uniprot id: Q6C497
names: Function
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.

284591:YALI0 B16940g
gene id: 284591:YALI0_B16940g
uniprot id: Q6CEB6
names: Similarity
messages: Belongs to the BLOC1S2 family.

284591:YALI0 C05599g
gene id: 284591:YALI0_C05599g
uniprot id: Q6CCY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family.
messages: Component of the nucleoplasmic and cytoplasmic pre-60S ribosomal particles.
messages: Cytoplasm
messages: Nucleus
messages: Probable metalloprotease involved in proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit. Accompanies the pre-60S particles to the cytoplasm (By similarity).

284591:YALI0 D16335g
gene id: 284591:YALI0_D16335g
uniprot id: Q6C8W6
names: Similarity
messages: Belongs to the peptidase C19 family.

284591:YALI0 C03399g
gene id: 284591:YALI0_C03399g
uniprot id: Q6CD66
names: Similarity
messages: Belongs to the PP2C family.

284591:YALI0 F25267g
gene id: 284591:YALI0_F25267g
uniprot id: Q6C0F0
names: Similarity
messages: Belongs to the SDO1/SBDS family.

284591:YALI0 E28237g
gene id: 284591:YALI0_E28237g
uniprot id: Q6C4B5
names: Similarity
messages: Belongs to the group II decarboxylase family.

284591:YALI0 D04961g
gene id: 284591:YALI0_D04961g
uniprot id: Q6CA87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.
messages: Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.
messages: Component of the SWR1 chromatin-remodeling complex.
messages: Nucleus

284591:YALI0 B05258g
gene id: 284591:YALI0_B05258g
uniprot id: Q6CFP0
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

284591:YALI0 B02332g
gene id: 284591:YALI0_B02332g
uniprot id: Q6CFZ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

284591:YALI0 B22770g
gene id: 284591:YALI0_B22770g
uniprot id: Q6CDM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRG7 family.
messages: Mitochondrion

284591:YALI0 F21373g
gene id: 284591:YALI0_F21373g
uniprot id: B5RSL9
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

284591:YALI0 E01892g
gene id: 284591:YALI0_E01892g
uniprot id: Q6C7C7
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

284591:YALI0 D01089g
gene id: 284591:YALI0_D01089g
uniprot id: Q6CAP2
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

284591:YALI0 B16500g
gene id: 284591:YALI0_B16500g
uniprot id: Q6CED6
names: Similarity
messages: Belongs to the peptidase S8 family.

284591:YALI0 E13376g
gene id: 284591:YALI0_E13376g
uniprot id: Q6C613
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

284591:YALI0 F16731g
gene id: 284591:YALI0_F16731g
uniprot id: Q6C1F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

284591:YALI0 D06688g
gene id: 284591:YALI0_D06688g
uniprot id: Q6CA15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

284591:YALI0 C03674g
gene id: 284591:YALI0_C03674g
uniprot id: Q6CD53
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

284591:YALI0 A10208g
gene id: 284591:YALI0_A10208g
uniprot id: Q6CHC7
names: Similarity
messages: Belongs to the peptidase S8 family.

284591:YALI0 B05126g
gene id: 284591:YALI0_B05126g
uniprot id: Q6CFP4
names: Similarity
messages: Belongs to the cytochrome P450 family.

284591:YALI0 E10461g
gene id: 284591:YALI0_E10461g
uniprot id: Q6C6D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle. Interacts with NOP7 and RRP1. Interacts with RSA4 (via WD repeats).
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity).
messages: nucleolus

284591:YALI0 E32681g
gene id: 284591:YALI0_E32681g
uniprot id: Q6C3R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

284591:YALI0 F13387g
gene id: 284591:YALI0_F13387g
uniprot id: Q6C1U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

284591:YALI0 D00715g
gene id: 284591:YALI0_D00715g
uniprot id: Q6CAQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to keep the TOM and the TIM23 complexes in close contact. At some point, it is released from the TOM23 complex to allow protein translocation into the mitochondrial matrix (By similarity).
messages: Mitochondrion inner membrane

284591:YALI0 C05302g
gene id: 284591:YALI0_C05302g
uniprot id: Q6CCZ4
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E05467g
gene id: 284591:YALI0_E05467g
uniprot id: Q6C6X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

284591:YALI0 C23100g
gene id: 284591:YALI0_C23100g
uniprot id: Q6CAZ7
names: Similarity
messages: Belongs to the TIP41 family.

284591:YALI0 F19580g
gene id: 284591:YALI0_F19580g
uniprot id: Q6C135
names: Subcellular Location Annotation
messages: Peroxisome membrane

284591:YALI0 C10450g
gene id: 284591:YALI0_C10450g
uniprot id: Q6CCD3
names: Similarity
messages: Belongs to the SUN family.

284591:YALI0 E19052g
gene id: 284591:YALI0_E19052g
uniprot id: Q6C5D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LOT5 family.
messages: Nucleus

284591:YALI0 C11627g
gene id: 284591:YALI0_C11627g
uniprot id: Q6CC81
names: Similarity
messages: Belongs to the cytochrome b5 family.

284591:YALI0 F26873g
gene id: 284591:YALI0_F26873g
uniprot id: Q6C088
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

284591:YALI0 B16478g
gene id: 284591:YALI0_B16478g
uniprot id: Q6CED7
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D21604g
gene id: 284591:YALI0_D21604g
uniprot id: Q6C893
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

284591:YALI0 D04224g
gene id: 284591:YALI0_D04224g
uniprot id: Q6CAB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ODC antizyme family.
messages: Interacts with ODC and thereby sterically blocks ODC homodimerization.
messages: Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome.

284591:YALI0 A09746g
gene id: 284591:YALI0_A09746g
uniprot id: Q6CHE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

284591:YALI0 B06600g
gene id: 284591:YALI0_B06600g
uniprot id: Q6CFI8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

284591:YALI0 E13057g
gene id: 284591:YALI0_E13057g
uniprot id: Q6C627
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
messages: Heterodimer of an alpha and a beta chain.
messages: Mitochondrion matrix
messages: The alpha and beta chains are autoproteolytically processed from a single precursor protein within the mitochondrion.
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

284591:YALI0 F17974g
gene id: 284591:YALI0_F17974g
uniprot id: Q6C1A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm
messages: Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity.
messages: Homohexamer. Binds to nucleic acids. Binds single-stranded DNA and RNA with higher affinity than double-stranded DNA.
messages: Mitochondrion
messages: The normal physiological role of the enzyme is unknown, but it is not essential for the viability of yeast cells. Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity. Acts as a repressor in the GAL4 regulatory system, but this does not require either the peptidase or nucleic acid-binding activities.

284591:YALI0 A09262g
gene id: 284591:YALI0_A09262g
uniprot id: F2Z604
names: Similarity
messages: Belongs to the peptidase S8 family.

284591:YALI0 E30591g
gene id: 284591:YALI0_E30591g
uniprot id: Q6C416
names: Similarity
messages: Belongs to the biotin--protein ligase family.

284591:YALI0 C20265g
gene id: 284591:YALI0_C20265g
uniprot id: Q6CBB8
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E17677g
gene id: 284591:YALI0_E17677g
uniprot id: Q6C5J0
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A09724g
gene id: 284591:YALI0_A09724g
uniprot id: Q6CHE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.
messages: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate-binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions (By similarity).
messages: Heterodimer consisting of MSH2-MSH3 (MutS beta). Forms a ternary complex with MutL alpha (MLH1-PMS1) (By similarity).
messages: Nucleus

284591:YALI0 E08338g
gene id: 284591:YALI0_E08338g
uniprot id: Q6C6M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid transfer protein required for autophagosome completion and peroxisome degradation. Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion. ATG2 binds to the ER exit site (ERES), which is the membrane source for autophagosome formation, using basic residues in its N-terminal region (NR) and to the expanding edge of the IM through its C-terminal region. The latter binding is assisted by an ATG18-PtdIns3P interaction. ATG2 then extracts phospholipids from the membrane source using its NR and transfers them to ATG9 to the IM through its predicted beta-sheet-rich structure for membrane expansion.
messages: Preautophagosomal structure membrane

284591:YALI0 B23078g
gene id: 284591:YALI0_B23078g
uniprot id: Q6CDL2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

284591:YALI0 B03564g
gene id: 284591:YALI0_B03564g
uniprot id: Q6CFU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

284591:YALI0 D17732g
gene id: 284591:YALI0_D17732g
uniprot id: Q6C8Q9
names: Similarity
messages: Belongs to the GCN1 family.

284591:YALI0 F28457g
gene id: 284591:YALI0_F28457g
uniprot id: Q99144
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
messages: Cytoplasm
messages: Peroxisome membrane
messages: Ubiquitination at Cys-10 is UBC4-independent but requires the presence of PEX4. Ubiquitination at Lys-22 is UBC4-dependent (By similarity).

284591:YALI0 C23925g
gene id: 284591:YALI0_C23925g
uniprot id: Q6CAW0
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

284591:YALI0 B22814g
gene id: 284591:YALI0_B22814g
uniprot id: Q6CDM4
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C21934g
gene id: 284591:YALI0_C21934g
uniprot id: Q6CB49
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

284591:YALI0 B14014g
gene id: 284591:YALI0_B14014g
uniprot id: Q6CEP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GMC oxidoreductase family.
messages: Peroxisome matrix

284591:YALI0 E23155g
gene id: 284591:YALI0_E23155g
uniprot id: Q6C4W6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.
messages: Endoplasmic reticulum lumen
messages: Inhibited by cyclosporin A (CsA).
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

284591:YALI0 E20119g
gene id: 284591:YALI0_E20119g
uniprot id: Q6C588
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

284591:YALI0 A02288g
gene id: 284591:YALI0_A02288g
uniprot id: Q6CI27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

284591:YALI0 F21747g
gene id: 284591:YALI0_F21747g
uniprot id: Q6C0U2
names: Function
names: Similarity
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.

284591:YALI0 E25762g
gene id: 284591:YALI0_E25762g
uniprot id: Q6C4L6
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 D21684g
gene id: 284591:YALI0_D21684g
uniprot id: W0TYN1
names: Subcellular Location Annotation
messages: Chromosome

284591:YALI0 F21835g
gene id: 284591:YALI0_F21835g
uniprot id: Q6C0T8
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 C02937g
gene id: 284591:YALI0_C02937g
uniprot id: Q6CD83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BIG1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 D14058g
gene id: 284591:YALI0_D14058g
uniprot id: Q6C950
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

284591:YALI0 D10329g
gene id: 284591:YALI0_D10329g
uniprot id: Q6C9K8
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.

284591:YALI0 D02475g
gene id: 284591:YALI0_D02475g
uniprot id: Q6CAI5
names: Subcellular Location Annotation
messages: Nucleus

284591:YALI0 F08591g
gene id: 284591:YALI0_F08591g
uniprot id: Q6C2E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAK10 family.
messages: Cytoplasm

284591:YALI0 A00418g
gene id: 284591:YALI0_A00418g
uniprot id: Q6CI95
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 C11561g
gene id: 284591:YALI0_C11561g
uniprot id: Q6CC84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SPT5 family.
messages: Component of the SPT4-SPT5 complex. Interacts with RNA polymerase II (By similarity).
messages: Nucleus
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).

284591:YALI0 E05841g
gene id: 284591:YALI0_E05841g
uniprot id: Q6C6V9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

284591:YALI0 E20867g
gene id: 284591:YALI0_E20867g
uniprot id: Q6C556
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

284591:YALI0 E23386g
gene id: 284591:YALI0_E23386g
uniprot id: Q6C4V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

284591:YALI0 B14399g
gene id: 284591:YALI0_B14399g
uniprot id: Q6CEN0
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

284591:YALI0 D09086g
gene id: 284591:YALI0_D09086g
uniprot id: Q6C9Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the SRB8-11 complex, which itself associates with the Mediator complex.
messages: Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
messages: Nucleus

284591:YALI0 E05137g
gene id: 284591:YALI0_E05137g
uniprot id: Q6C6Z1
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

284591:YALI0 E17413g
gene id: 284591:YALI0_E17413g
uniprot id: Q6C5K0
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

284591:YALI0 F00572g
gene id: 284591:YALI0_F00572g
uniprot id: Q6C3D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Cytoplasm
messages: MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle.
messages: Nucleus

284591:YALI0 C07546g
gene id: 284591:YALI0_C07546g
uniprot id: Q6CCQ2
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

284591:YALI0 B21978g
gene id: 284591:YALI0_B21978g
uniprot id: Q6CDQ9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

284591:YALI0 E21307g
gene id: 284591:YALI0_E21307g
uniprot id: Q6C538
names: Similarity
messages: Belongs to the cytochrome b5 family.

284591:YALI0 F03047g
gene id: 284591:YALI0_F03047g
uniprot id: Q6C331
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM16/PAM16 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity).
messages: Heterodimer with PAM18. Component of the PAM complex, at least composed of mtHsp70, MGE1, TIM44, PAM16, PAM17 and PAM18 (By similarity).
messages: Mitochondrion inner membrane
messages: The J-like region, although related to the J domain does not stimulate ATPase activity of mtHSP70. It nevertheless mediates the heterodimerization with the J domain of PAM18 and is therefore essential for PAM complex function (By similarity).

284591:YALI0 F06372g
gene id: 284591:YALI0_F06372g
uniprot id: Q6C2N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.
messages: Nucleus

284591:YALI0 D24926g
gene id: 284591:YALI0_D24926g
uniprot id: Q6C7W0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM34 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
messages: Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.
messages: Mitochondrion outer membrane
messages: The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.

284591:YALI0 A18656g
gene id: 284591:YALI0_A18656g
uniprot id: Q6CGK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM3 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.

284591:YALI0 E28941g
gene id: 284591:YALI0_E28941g
uniprot id: Q6C483
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 D08492g
gene id: 284591:YALI0_D08492g
uniprot id: Q6C9T6
names: Similarity
messages: Belongs to the SEC6 family.

284591:YALI0 A09900g
gene id: 284591:YALI0_A09900g
uniprot id: Q6CHD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Endomembrane system
messages: Vacuole membrane

284591:YALI0 F13123g
gene id: 284591:YALI0_F13123g
uniprot id: Q6C1V4
names: Similarity
messages: Belongs to the HUS1 family.

284591:YALI0 F27313g
gene id: 284591:YALI0_F27313g
uniprot id: Q6C071
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

284591:YALI0 E25652g
gene id: 284591:YALI0_E25652g
uniprot id: Q6C4M1
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

284591:YALI0 D12342g
gene id: 284591:YALI0_D12342g
uniprot id: Q6C9C3
names: Function
names: Similarity
messages: Belongs to the CTR86 family.
messages: Essential protein which may be involved in threonine biosynthesis.

284591:YALI0 C16456g
gene id: 284591:YALI0_C16456g
uniprot id: Q6CBQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the respiratory chain complex III/complex IV supercomplex.
messages: Belongs to the RCF1 family.
messages: Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
messages: Mitochondrion membrane

284591:YALI0 A07579g
gene id: 284591:YALI0_A07579g
uniprot id: Q6CHL8
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E25784g
gene id: 284591:YALI0_E25784g
uniprot id: Q6C4L5
names: Similarity
messages: Belongs to the peptidase A1 family.

284591:YALI0 C05148g
gene id: 284591:YALI0_C05148g
uniprot id: Q6CCZ9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

284591:YALI0 D08635g
gene id: 284591:YALI0_D08635g
uniprot id: B5FVE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 D15598g
gene id: 284591:YALI0_D15598g
uniprot id: Q6C8Z4
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

284591:YALI0 F19646g
gene id: 284591:YALI0_F19646g
uniprot id: Q6C132
names: Similarity
messages: Belongs to the peptidase S8 family.

284591:YALI0 B00968g
gene id: 284591:YALI0_B00968g
uniprot id: Q6CG45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

284591:YALI0 E03190g
gene id: 284591:YALI0_E03190g
uniprot id: Q6C774
names: Function
names: Subcellular Location Annotation
messages: Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 E29623g
gene id: 284591:YALI0_E29623g
uniprot id: Q6C452
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAD1 family.
messages: Central component of the spindle assembly checkpoint.
messages: Nucleus

284591:YALI0 E20427g
gene id: 284591:YALI0_E20427g
uniprot id: Q6C576
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 B21538g
gene id: 284591:YALI0_B21538g
uniprot id: Q6CDS6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
messages: Interacts with the U3 snoRNA and is associated with the 90S and 40S pre-ribosomes.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

284591:YALI0 B11286g
gene id: 284591:YALI0_B11286g
uniprot id: Q6CF09
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

284591:YALI0 F20394g
gene id: 284591:YALI0_F20394g
uniprot id: Q6C101
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Regulates the cell cycle in a nutrient dependent manner.

284591:YALI0 F18722g
gene id: 284591:YALI0_F18722g
uniprot id: Q6C171
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

284591:YALI0 B22066g
gene id: 284591:YALI0_B22066g
uniprot id: Q6CDQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
messages: Cell membrane
messages: The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.

284591:YALI0 A21153g
gene id: 284591:YALI0_A21153g
uniprot id: Q6CG92
names: Similarity
messages: Belongs to the isochorismatase family.

284591:YALI0 E32208g
gene id: 284591:YALI0_E32208g
uniprot id: B5FVG4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

284591:YALI0 D12320g
gene id: 284591:YALI0_D12320g
uniprot id: Q6C9C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL27 family.
messages: Component of the large subunit of mitochondrial ribosome.
messages: Mitochondrion

284591:YALI0 D04004g
gene id: 284591:YALI0_D04004g
uniprot id: Q6CAC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Component of the SRB8-11 complex, a regulatory module of the Mediator complex.
messages: Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity).
messages: Nucleus

284591:YALI0 E17809g
gene id: 284591:YALI0_E17809g
uniprot id: Q6C5I4
names: Similarity
messages: Belongs to the TAF11 family.

284591:YALI0 F05236g
gene id: 284591:YALI0_F05236g
uniprot id: Q6C2T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DASH complex DAM1 family.
messages: Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
messages: Nucleus
messages: The DASH complex oligomerizes to form rings that encircle the microtubules.
messages: kinetochore
messages: spindle

284591:YALI0 E27676g
gene id: 284591:YALI0_E27676g
uniprot id: Q6C4D6
names: Similarity
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.

284591:YALI0 A18062g
gene id: 284591:YALI0_A18062g
uniprot id: Q6CGM4
names: Similarity
messages: Belongs to the cytochrome P450 family.

284591:YALI0 F10769g
gene id: 284591:YALI0_F10769g
uniprot id: Q6C253
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M76 family.
messages: Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity).
messages: Mitochondrion inner membrane

284591:YALI0 E15708g
gene id: 284591:YALI0_E15708g
uniprot id: Q6C5R9
names: Similarity
messages: Belongs to the malate synthase family.

284591:YALI0 E21131g
gene id: 284591:YALI0_E21131g
uniprot id: Q6C544
names: Function
messages: Delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides. Required for the formation of the di-unsaturated sphingoid base (E,E)-sphinga-4,8-dienine during glucosylceramide (GluCer) biosynthesis.

284591:YALI0 B08338g
gene id: 284591:YALI0_B08338g
uniprot id: Q6CFC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the midasin family.
messages: Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits.
messages: nucleolus
messages: nucleoplasm

284591:YALI0 D20944g
gene id: 284591:YALI0_D20944g
uniprot id: Q6C8B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

284591:YALI0 C00165g
gene id: 284591:YALI0_C00165g
uniprot id: Q6CDI9
names: Similarity
messages: Belongs to the peptidase M67C family.

284591:YALI0 C12276g
gene id: 284591:YALI0_C12276g
uniprot id: Q6CC57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Mitochondrion inner membrane

284591:YALI0 B07898g
gene id: 284591:YALI0_B07898g
uniprot id: Q6CFE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284591:YALI0 E14124g
gene id: 284591:YALI0_E14124g
uniprot id: Q6C5Y2
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

284591:YALI0 B05566g
gene id: 284591:YALI0_B05566g
uniprot id: Q6CFM7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

284591:YALI0 F13101g
gene id: 284591:YALI0_F13101g
uniprot id: Q6C1V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CGR1 family.
messages: Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.
messages: nucleolus

284591:YALI0 B16654g
gene id: 284591:YALI0_B16654g
uniprot id: Q6CEC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSA1 family.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

284591:YALI0 F31559g
gene id: 284591:YALI0_F31559g
uniprot id: Q6BZR1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

284591:YALI0 D23397g
gene id: 284591:YALI0_D23397g
uniprot id: Q6C823
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

284591:YALI0 E00836g
gene id: 284591:YALI0_E00836g
uniprot id: Q6C7H3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. MetX family.

284591:YALI0 E18524g
gene id: 284591:YALI0_E18524g
uniprot id: Q6C5F5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily.

284591:YALI0 C00539g
gene id: 284591:YALI0_C00539g
uniprot id: Q6CDH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and regulates mRNA decay through translation termination-coupled poly(A) shortening, probably mediated by PAN (By similarity).
messages: Cytoplasm
messages: Nucleus

284591:YALI0 F23903g
gene id: 284591:YALI0_F23903g
uniprot id: Q6C0K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

284591:YALI0 D14894g
gene id: 284591:YALI0_D14894g
uniprot id: Q6C924
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

284591:YALI0 E24475g
gene id: 284591:YALI0_E24475g
uniprot id: Q6C4Q8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

284591:YALI0 F10032g
gene id: 284591:YALI0_F10032g
uniprot id: Q6C281
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

284591:YALI0 E35112g
gene id: 284591:YALI0_E35112g
uniprot id: Q6C3G3
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 A06908g
gene id: 284591:YALI0_A06908g
uniprot id: Q6CHN5
names: Function
names: Similarity
messages: Belongs to the POA1 family.
messages: Highly specific phosphatase involved in the metabolism of ADP-ribose 1''-phosphate (Appr1p) which is produced as a consequence of tRNA splicing.

284591:YALI0 A21197g
gene id: 284591:YALI0_A21197g
uniprot id: Q6CG90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

284591:YALI0 E11913g
gene id: 284591:YALI0_E11913g
uniprot id: Q6C673
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by ATP (By similarity). ATP binding is a prerequisite to magnesium and substrate binding. ATP binds to 2 of the subunits in the homotetramer inducing a closure of these 2 subunits and the release of the C-terminal loop, thereby activating the enzyme (By similarity).
messages: Belongs to the ISN1 family.
messages: Homotetramer.
messages: IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation.

284591:YALI0 B23298g
gene id: 284591:YALI0_B23298g
uniprot id: Q6CDK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

284591:YALI0 F09405g
gene id: 284591:YALI0_F09405g
uniprot id: Q6C2A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.

284591:YALI0 D20108g
gene id: 284591:YALI0_D20108g
uniprot id: Q6C8F4
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

284591:YALI0 B10263g
gene id: 284591:YALI0_B10263g
uniprot id: Q6CF50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTU2/NCS2 family.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

284591:YALI0 C02541g
gene id: 284591:YALI0_C02541g
uniprot id: Q6CD98
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 E17589g
gene id: 284591:YALI0_E17589g
uniprot id: Q6C5J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

284591:YALI0 B03520g
gene id: 284591:YALI0_B03520g
uniprot id: Q6CFU9
names: Similarity
messages: Belongs to the cullin family.

284591:YALI0 F11935g
gene id: 284591:YALI0_F11935g
uniprot id: Q6C203
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

284591:YALI0 E26653g
gene id: 284591:YALI0_E26653g
uniprot id: Q6C4H8
names: Similarity
messages: Belongs to the TMCO4 family.

284591:YALI0 D06842g
gene id: 284591:YALI0_D06842g
uniprot id: Q6CA08
names: Domain
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DENR family.
messages: Cytoplasm
messages: Interacts with the 40S ribosomal subunit.
messages: The SUI1 domain may be involved in RNA binding.

284591:YALI0 F03498g
gene id: 284591:YALI0_F03498g
uniprot id: Q6C312
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 F15411g
gene id: 284591:YALI0_F15411g
uniprot id: Q6C1K6
names: Subcellular Location Annotation
messages: Membrane

284591:YALI0 D12947g
gene id: 284591:YALI0_D12947g
uniprot id: Q6C994
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAR5 family.
messages: Endoplasmic reticulum membrane
messages: Nucleus membrane
messages: Required for nuclear membrane fusion during karyogamy.

284591:YALI0 D07678g
gene id: 284591:YALI0_D07678g
uniprot id: Q6C9X0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Endomembrane system
messages: Endosome membrane
messages: May be required for cytoplasm to vacuole transport (Cvt) and pexophagy.
messages: The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization to the perivacuolar punctate structures.

284591:YALI0 F24475g
gene id: 284591:YALI0_F24475g
uniprot id: Q6C0I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

284591:YALI0 E33539g
gene id: 284591:YALI0_E33539g
uniprot id: Q6C3M7
names: Similarity
messages: Belongs to the SUN family.