28377:LOC100555786
gene id: 28377:LOC100555786
uniprot id: A0A803TLL5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Snake venom subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:sirt5
gene id: 28377:sirt5
uniprot id: G1KC04
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-106 and Arg-109) that bind to malonylated and succinylated substrates and define the specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
messages: Nucleus
messages: cytosol

28377:tes
gene id: 28377:tes
uniprot id: G1KFK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prickle / espinas / testin family.
messages: focal adhesion

28377:ribc2
gene id: 28377:ribc2
uniprot id: G1KQ77
names: Similarity
messages: Belongs to the RIB43A family.

28377:uba5
gene id: 28377:uba5
uniprot id: G1K8M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
messages: Golgi apparatus

28377:notch3
gene id: 28377:notch3
uniprot id: G1KTN8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

28377:tmem184c
gene id: 28377:tmem184c
uniprot id: G1KCB4
names: Subcellular Location Annotation
messages: Membrane

28377:nr2e1
gene id: 28377:nr2e1
uniprot id: G1KEV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

28377:LOC100559794
gene id: 28377:LOC100559794
uniprot id: R4GBW2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

28377:p4ha2
gene id: 28377:p4ha2
uniprot id: A0A803SW13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

28377:tph2
gene id: 28377:tph2
uniprot id: G1KGT8
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

28377:enpp6
gene id: 28377:enpp6
uniprot id: G1KBD6
names: Similarity
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.

28377:LOC100557814
gene id: 28377:LOC100557814
uniprot id: A0A803SQC0
uniprot id: G1KBH3
names: Similarity
messages: Belongs to the aldo/keto reductase family.

28377:LOC100553834
gene id: 28377:LOC100553834
uniprot id: A0A803U023
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction.
messages: Membrane

28377:irx4
gene id: 28377:irx4
uniprot id: G1K8P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

28377:atad2
gene id: 28377:atad2
uniprot id: G1KJ60
names: Similarity
messages: Belongs to the AAA ATPase family.

28377:areg
gene id: 28377:areg
uniprot id: R4GAL3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:slc26a6
gene id: 28377:slc26a6
uniprot id: G1K940
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:rap2b
gene id: 28377:rap2b
uniprot id: G1KL05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

28377:pif1
gene id: 28377:pif1
uniprot id: G1KND2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
messages: Mitochondrion
messages: Monomer.
messages: Nucleus

28377:fkbp6
gene id: 28377:fkbp6
uniprot id: G1KG59
names: Function
names: Similarity
messages: Belongs to the FKBP6 family.
messages: Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes.

28377:b4galt5
gene id: 28377:b4galt5
uniprot id: G1KRN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

28377:gjd3
gene id: 28377:gjd3
uniprot id: G1KAM8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28377:hbp1
gene id: 28377:hbp1
uniprot id: G1KQL8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

28377:LOC100563609
gene id: 28377:LOC100563609
uniprot id: R4G924
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:ppargc1a
gene id: 28377:ppargc1a
uniprot id: G1K8Y9
names: Subcellular Location Annotation
messages: PML body

28377:slc28a3
gene id: 28377:slc28a3
uniprot id: G1K9F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

28377:zeb1
gene id: 28377:zeb1
uniprot id: A0A803U028
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

28377:etv1
gene id: 28377:etv1
uniprot id: A0A803TE69
uniprot id: A0A803TGZ3
uniprot id: A0A803TL52
uniprot id: G1KNE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

28377:LOC107982633
gene id: 28377:LOC107982633
uniprot id: G1KY08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S1 family. Snake venom subfamily.
messages: Heterodimer of a light chain and a heavy chain linked by a disulfide bond.
messages: Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:sucnr1
gene id: 28377:sucnr1
uniprot id: R4G9L5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:serinc5
gene id: 28377:serinc5
uniprot id: G1KSQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Cell membrane
messages: Membrane

28377:mmp13
gene id: 28377:mmp13
uniprot id: G1KMI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Secreted

28377:traf5
gene id: 28377:traf5
uniprot id: G1KSI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

28377:isl1
gene id: 28377:isl1
uniprot id: G1KCT9
uniprot id: R4GCB0
names: Subcellular Location Annotation
messages: Nucleus

28377:bpnt1
gene id: 28377:bpnt1
uniprot id: G1K9J6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

28377:ddx18
gene id: 28377:ddx18
uniprot id: G1KAA2
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.

28377:exosc9
gene id: 28377:exosc9
uniprot id: G1KMQ7
names: Subcellular Location Annotation
messages: Cytoplasm

28377:LOC100556505
gene id: 28377:LOC100556505
uniprot id: G1KB86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

28377:rad50
gene id: 28377:rad50
uniprot id: G1KMS1
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

28377:alg6
gene id: 28377:alg6
uniprot id: G1KHE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:trmt10c
gene id: 28377:trmt10c
uniprot id: G1KXE4
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

28377:LOC100555334
gene id: 28377:LOC100555334
uniprot id: G1KNY2
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

28377:pomt2
gene id: 28377:pomt2
uniprot id: G1KTL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

28377:h3f3a
gene id: 28377:h3f3a
uniprot id: G1KGC9
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

28377:cdk7
gene id: 28377:cdk7
uniprot id: G1KSN0
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

28377:psmd11
gene id: 28377:psmd11
uniprot id: G1KSS2
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

28377:rev3l
gene id: 28377:rev3l
uniprot id: G1KL83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

28377:nfe2l1
gene id: 28377:nfe2l1
uniprot id: G1KFJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. CNC subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

28377:ndfip1
gene id: 28377:ndfip1
uniprot id: G1KNQ5
names: Subcellular Location Annotation
messages: Membrane

28377:osbpl3
gene id: 28377:osbpl3
uniprot id: A0A803TZF3
uniprot id: G1KND1
names: Similarity
messages: Belongs to the OSBP family.

28377:LOC100556190
gene id: 28377:LOC100556190
uniprot id: R4GAA4
names: Similarity
messages: Belongs to the amidase family.

28377:grk7
gene id: 28377:grk7
uniprot id: G1KDL7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

28377:LOC103279307
gene id: 28377:LOC103279307
uniprot id: A0A803T107
uniprot id: H9G8X6
names: Subcellular Location Annotation
messages: Secreted

28377:actr3
gene id: 28377:actr3
uniprot id: G1KB09
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

28377:maml2
gene id: 28377:maml2
uniprot id: G1KNX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

28377:tjp2
gene id: 28377:tjp2
uniprot id: A0A803TTD2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

28377:dnmt3l
gene id: 28377:dnmt3l
uniprot id: A0A803TK47
uniprot id: R4GDL3
names: Subcellular Location Annotation
messages: Nucleus

28377:tcp1
gene id: 28377:tcp1
uniprot id: A0A803TJF7
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

28377:ndufv1
gene id: 28377:ndufv1
uniprot id: G1KJW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

28377:gpd1l
gene id: 28377:gpd1l
uniprot id: G1KQ41
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

28377:psmb6
gene id: 28377:psmb6
uniprot id: G1KJL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

28377:rb1
gene id: 28377:rb1
uniprot id: G1KBZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

28377:romo1
gene id: 28377:romo1
uniprot id: G1KFC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

28377:ing5
gene id: 28377:ing5
uniprot id: G1K8N5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

28377:des
gene id: 28377:des
uniprot id: G1KPB3
names: Similarity
messages: Belongs to the intermediate filament family.

28377:suclg2
gene id: 28377:suclg2
uniprot id: A0A803T2D4
uniprot id: G1KQT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.
messages: Mitochondrion

28377:LOC100551724
gene id: 28377:LOC100551724
uniprot id: A0A803TRT8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

28377:fip1l1
gene id: 28377:fip1l1
uniprot id: A0A803T897
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

28377:LOC100566883
gene id: 28377:LOC100566883
uniprot id: V5ZDW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

28377:cygb
gene id: 28377:cygb
uniprot id: A0A803TN90
names: Similarity
messages: Belongs to the globin family.

28377:LOC100559672
gene id: 28377:LOC100559672
uniprot id: H9GHD5
names: Subcellular Location Annotation
messages: Nucleus

28377:epn3
gene id: 28377:epn3
uniprot id: G1KDN4
names: Similarity
messages: Belongs to the epsin family.

28377:LOC100565035
gene id: 28377:LOC100565035
uniprot id: A0A803TU23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

28377:c6h18orf21
gene id: 28377:c6h18orf21
uniprot id: G1KFS9
names: Similarity
messages: Belongs to the UPF0711 family.

28377:proz
gene id: 28377:proz
uniprot id: G1K8D2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:c1d
gene id: 28377:c1d
uniprot id: G1K9A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the C1D family.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Nucleus
messages: Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
messages: nucleolus

28377:ednra
gene id: 28377:ednra
uniprot id: G1KCC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

28377:plk2
gene id: 28377:plk2
uniprot id: G1KIX7
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

28377:LOC100554808
gene id: 28377:LOC100554808
uniprot id: A0A803SRW6
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

28377:agl
gene id: 28377:agl
uniprot id: A0A803SN98
uniprot id: G1KCM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

28377:znf326
gene id: 28377:znf326
uniprot id: G1K968
names: Similarity
messages: Belongs to the AKAP95 family.

28377:pdia4
gene id: 28377:pdia4
uniprot id: G1KPJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

28377:ston1
gene id: 28377:ston1
uniprot id: G1KPS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Cytoplasm
messages: May be involved in the endocytic machinery.

28377:galm
gene id: 28377:galm
uniprot id: G1KEZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldose epimerase family.
messages: Monomer.
messages: Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism.

28377:taf4b
gene id: 28377:taf4b
uniprot id: G1KA85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

28377:vars2
gene id: 28377:vars2
uniprot id: G1KUT8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

28377:ecsit
gene id: 28377:ecsit
uniprot id: G1KTD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ECSIT family.
messages: Cytoplasm
messages: Mitochondrion
messages: Nucleus

28377:LOC100555314
gene id: 28377:LOC100555314
uniprot id: G1KTZ2
names: Similarity
messages: Belongs to the CD225/Dispanin family.

28377:olfm3
gene id: 28377:olfm3
uniprot id: A0A803T5C9
uniprot id: G1KBH1
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

28377:msh3
gene id: 28377:msh3
uniprot id: G1KKD1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

28377:dars
gene id: 28377:dars
uniprot id: G1K905
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

28377:LOC100553709
gene id: 28377:LOC100553709
uniprot id: G1KLF6
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

28377:LOC100552570
gene id: 28377:LOC100552570
uniprot id: G1KHZ0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

28377:LOC100337545
gene id: 28377:LOC100337545
uniprot id: B6Z1W5
names: Similarity
messages: Belongs to the intermediate filament family.

28377:usp37
gene id: 28377:usp37
uniprot id: G1KAT4
names: Similarity
messages: Belongs to the peptidase C19 family.

28377:LOC100555460
gene id: 28377:LOC100555460
uniprot id: G1KG29
names: Similarity
messages: Belongs to the peptidase M14 family.

28377:agtr1
gene id: 28377:agtr1
uniprot id: G1KFX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

28377:LOC100555389
gene id: 28377:LOC100555389
uniprot id: G1KNB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

28377:sdha
gene id: 28377:sdha
uniprot id: G1KJ75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

28377:bmpr1b
gene id: 28377:bmpr1b
uniprot id: G1KP73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: Secreted

28377:lin7a
gene id: 28377:lin7a
uniprot id: G1KPW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

28377:osgepl1
gene id: 28377:osgepl1
uniprot id: G1KPS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Mitochondrion
messages: Monomer.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

28377:wtap
gene id: 28377:wtap
uniprot id: G1KCU9
names: Similarity
messages: Belongs to the fl(2)d family.

28377:adcy8
gene id: 28377:adcy8
uniprot id: A0A803TL20
uniprot id: G1KKD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

28377:tsc22d2
gene id: 28377:tsc22d2
uniprot id: A0A803SUG0
uniprot id: G1KGW9
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

28377:pax6
gene id: 28377:pax6
uniprot id: A0A803TIT1
uniprot id: G1KAP0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

28377:lhpp
gene id: 28377:lhpp
uniprot id: A0A803T2P1
uniprot id: G1KU51
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

28377:LOC100556182
gene id: 28377:LOC100556182
uniprot id: G1KUN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

28377:LOC100567765
gene id: 28377:LOC100567765
uniprot id: G1KTI9
names: Similarity
messages: Belongs to the TTC39 family.

28377:cep57
gene id: 28377:cep57
uniprot id: G1KP63
names: Similarity
messages: Belongs to the translokin family.

28377:LOC107982244
gene id: 28377:LOC107982244
uniprot id: A0A803SYY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

28377:adi1
gene id: 28377:adi1
uniprot id: G1KEU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

28377:ywhaz
gene id: 28377:ywhaz
uniprot id: A0A803TEF5
names: Similarity
messages: Belongs to the 14-3-3 family.

28377:kiaa0391
gene id: 28377:kiaa0391
uniprot id: G1KA25
names: Similarity
messages: Belongs to the PPR family. P subfamily.

28377:tmed5
gene id: 28377:tmed5
uniprot id: G1KEJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

28377:LOC100561542
gene id: 28377:LOC100561542
uniprot id: G1KNN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

28377:LOC100557693
gene id: 28377:LOC100557693
uniprot id: G1K8Z8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

28377:sema3b
gene id: 28377:sema3b
uniprot id: G1KIX8
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:gart
gene id: 28377:gart
uniprot id: A0A803SP58
uniprot id: G1KD17
names: Similarity
messages: In the C-terminal section; belongs to the GART family.
messages: In the N-terminal section; belongs to the GARS family.
messages: In the central section; belongs to the AIR synthase family.

28377:lgr6
gene id: 28377:lgr6
uniprot id: G1KCW5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28377:dtx3l
gene id: 28377:dtx3l
uniprot id: G1KJ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

28377:cep63
gene id: 28377:cep63
uniprot id: G1KJ28
names: Similarity
messages: Belongs to the CEP63 family.

28377:tmem267
gene id: 28377:tmem267
uniprot id: G1KKJ1
names: Subcellular Location Annotation
messages: Membrane

28377:LOC100561560
gene id: 28377:LOC100561560
uniprot id: G1KAI2
names: Similarity
messages: Belongs to the thioesterase PaaI family.

28377:ttc39c
gene id: 28377:ttc39c
uniprot id: G1K992
names: Similarity
messages: Belongs to the TTC39 family.

28377:osbpl7
gene id: 28377:osbpl7
uniprot id: G1KG14
names: Similarity
messages: Belongs to the OSBP family.

28377:LOC100562946
gene id: 28377:LOC100562946
uniprot id: G1KEI6
names: Similarity
messages: Belongs to the CBP3 family.

28377:LOC100566097
gene id: 28377:LOC100566097
uniprot id: A0A803T806
names: Subcellular Location Annotation
messages: Membrane

28377:tlr2
gene id: 28377:tlr2
uniprot id: G1KUN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
messages: Membrane

28377:qpct
gene id: 28377:qpct
uniprot id: G1K927
names: Function
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.
messages: Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation.

28377:hsp90b1
gene id: 28377:hsp90b1
uniprot id: G1KSD1
names: Similarity
messages: Belongs to the heat shock protein 90 family.

28377:cnih3
gene id: 28377:cnih3
uniprot id: A0A803TVG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

28377:myd88
gene id: 28377:myd88
uniprot id: R4GCS1
names: Function
names: Subcellular Location Annotation
messages: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
messages: Cytoplasm

28377:slco1a2
gene id: 28377:slco1a2
uniprot id: A0A803SKW6
uniprot id: G1KTZ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:acvr1b
gene id: 28377:acvr1b
uniprot id: A0A803SW16
uniprot id: G1KT77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: Secreted

28377:dync1li1
gene id: 28377:dync1li1
uniprot id: G1KQ93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

28377:tyrp1
gene id: 28377:tyrp1
uniprot id: G1KL56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

28377:pomk
gene id: 28377:pomk
uniprot id: G1KIL5
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif.

28377:sox21
gene id: 28377:sox21
uniprot id: G1KAS3
names: Subcellular Location Annotation
messages: Nucleus

28377:pdp1
gene id: 28377:pdp1
uniprot id: G1KBZ9
names: Similarity
messages: Belongs to the PP2C family.

28377:slc29a3
gene id: 28377:slc29a3
uniprot id: G1KRZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

28377:fgf6
gene id: 28377:fgf6
uniprot id: A0A803SL30
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

28377:atp6v1e1
gene id: 28377:atp6v1e1
uniprot id: G1KMC4
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

28377:rbks
gene id: 28377:rbks
uniprot id: G1KWF4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

28377:avpr1a
gene id: 28377:avpr1a
uniprot id: G1K8H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

28377:aip
gene id: 28377:aip
uniprot id: G1KJA3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with RET in the pituitary gland; this interaction prevents the formation of the AIP-survivin complex.
messages: May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting.

28377:slc35f1
gene id: 28377:slc35f1
uniprot id: G1KPT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

28377:pkn1
gene id: 28377:pkn1
uniprot id: G1KTB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

28377:LOC100563580
gene id: 28377:LOC100563580
uniprot id: G1KUQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

28377:usp14
gene id: 28377:usp14
uniprot id: A0A803TII2
uniprot id: G1KHK9
names: Similarity
names: Subunit
messages: Belongs to the peptidase C19 family. USP14/UBP6 subfamily.
messages: Homodimer (Potential). Associates with the 26S proteasome. Interacts with FANCC, CXCR4 and ERN1. Interacts with TRIM14; this interaction recruits USP14 to cleave ubiquitin chains of CGAS.

28377:b9d2
gene id: 28377:b9d2
uniprot id: H9G827
names: Subcellular Location Annotation
messages: cilium basal body

28377:mme
gene id: 28377:mme
uniprot id: G1KCJ6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

28377:man1a1
gene id: 28377:man1a1
uniprot id: G1KUB9
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

28377:kansl2
gene id: 28377:kansl2
uniprot id: G1KI58
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
messages: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.
messages: Nucleus

28377:got1
gene id: 28377:got1
uniprot id: G1KC46
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

28377:cry2
gene id: 28377:cry2
uniprot id: G1KQ76
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

28377:tmem59
gene id: 28377:tmem59
uniprot id: G1KPI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

28377:slc6a17
gene id: 28377:slc6a17
uniprot id: G1KMN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

28377:naaladl2
gene id: 28377:naaladl2
uniprot id: R4GB38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Membrane

28377:akap3
gene id: 28377:akap3
uniprot id: G1KJ24
names: Similarity
messages: Belongs to the AKAP110 family.

28377:rbm6
gene id: 28377:rbm6
uniprot id: G1KHX7
names: Subcellular Location Annotation
messages: Nucleus

28377:slc6a7
gene id: 28377:slc6a7
uniprot id: G1KQY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

28377:asip
gene id: 28377:asip
uniprot id: A0A803SW56
uniprot id: A0A803TJ35
names: Subcellular Location Annotation
messages: Secreted

28377:d2hgdh
gene id: 28377:d2hgdh
uniprot id: G1K8L8
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

28377:rag1
gene id: 28377:rag1
uniprot id: G1KDK1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAG1 family.
messages: Binds 1 divalent metal cation per subunit. Mg(2+) or Mn(2+).
messages: Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.
messages: Homodimer.
messages: Nucleus
messages: The NBD (nonamer binding) DNA-binding domain mediates the specific binding to the nonamer RSS motif by forming a tightly interwoven homodimer that binds and synapses 2 nonamer elements, with each NBD making contact with both DNA molecules. Each RSS is composed of well-conserved heptamer (consensus 5'-CACAGTG-3') and nonamer (consensus 5'-ACAAAAACC-3') sequences separated by a spacer of either 12 bp or 23 bp.

28377:vwc2l
gene id: 28377:vwc2l
uniprot id: A0A803TY67
uniprot id: G1KR36
names: Subcellular Location Annotation
messages: Synapse

28377:best4
gene id: 28377:best4
uniprot id: G1KRF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

28377:ccr7
gene id: 28377:ccr7
uniprot id: A0A803SVQ2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:foxo1
gene id: 28377:foxo1
uniprot id: G1KSU9
names: Subcellular Location Annotation
messages: Nucleus

28377:tmem47
gene id: 28377:tmem47
uniprot id: G1KS28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

28377:cdk2ap2
gene id: 28377:cdk2ap2
uniprot id: G1KJR5
names: Similarity
messages: Belongs to the CDK2AP family.

28377:gsx2
gene id: 28377:gsx2
uniprot id: G1KX04
names: Subcellular Location Annotation
messages: Nucleus

28377:itpr2
gene id: 28377:itpr2
uniprot id: G1KLX9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

28377:cd79b
gene id: 28377:cd79b
uniprot id: A0A803TUE3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28377:pmpcb
gene id: 28377:pmpcb
uniprot id: G1KFG6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family.
messages: Heterodimer of PMPCA (alpha) and PMPCB (beta) subunits, forming the mitochondrial processing protease (MPP) in which PMPCA is involved in substrate recognition and binding and PMPCB is the catalytic subunit.
messages: Mitochondrion matrix

28377:nfib
gene id: 28377:nfib
uniprot id: A0A803T720
uniprot id: G1KUE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

28377:adra2a
gene id: 28377:adra2a
uniprot id: G1KRQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:lrrc8b
gene id: 28377:lrrc8b
uniprot id: G1KZ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

28377:sec61b
gene id: 28377:sec61b
uniprot id: G1KIE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

28377:esf1
gene id: 28377:esf1
uniprot id: G1K8X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

28377:galc
gene id: 28377:galc
uniprot id: G1KNS6
names: Similarity
messages: Belongs to the glycosyl hydrolase 59 family.

28377:mdm4
gene id: 28377:mdm4
uniprot id: G1KGI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.
messages: Nucleus

28377:dhps
gene id: 28377:dhps
uniprot id: G1KCS7
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

28377:prpf38a
gene id: 28377:prpf38a
uniprot id: G1KHK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRP38 family.
messages: Component of the spliceosome B complex.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: Nucleus

28377:LOC100557468
gene id: 28377:LOC100557468
uniprot id: A0A803T3I3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28377:LOC100553581
gene id: 28377:LOC100553581
uniprot id: H9G8Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNF-like-inhibitor family.
messages: Secreted

28377:taz
gene id: 28377:taz
uniprot id: G1KMR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the taffazin family.
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane

28377:LOC100554601
gene id: 28377:LOC100554601
uniprot id: L7MZF7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:slc7a11
gene id: 28377:slc7a11
uniprot id: G1KA07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Membrane

28377:adcyap1r1
gene id: 28377:adcyap1r1
uniprot id: A0A803THH6
uniprot id: G1KFA9
names: Subcellular Location Annotation
messages: Membrane

28377:LOC100563850
gene id: 28377:LOC100563850
uniprot id: G1KJR4
names: Similarity
messages: Belongs to the 14-3-3 family.

28377:nit2
gene id: 28377:nit2
uniprot id: G1KL30
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

28377:psmc5
gene id: 28377:psmc5
uniprot id: G1KUJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

28377:map2k6
gene id: 28377:map2k6
uniprot id: R4GDI3
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:il12b
gene id: 28377:il12b
uniprot id: G1KRP1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-12B family.
messages: Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

28377:slc22a18
gene id: 28377:slc22a18
uniprot id: G1KZB5
names: Subcellular Location Annotation
messages: Membrane

28377:LOC100558930
gene id: 28377:LOC100558930
uniprot id: G1KPV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

28377:sec23b
gene id: 28377:sec23b
uniprot id: G1KGF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

28377:ing2
gene id: 28377:ing2
uniprot id: G1KFY5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

28377:fgd5
gene id: 28377:fgd5
uniprot id: G1KLT5
names: Subcellular Location Annotation
messages: cytoskeleton

28377:lancl1
gene id: 28377:lancl1
uniprot id: G1KKC6
names: Similarity
messages: Belongs to the LanC-like protein family.

28377:shroom1
gene id: 28377:shroom1
uniprot id: A0A803TN87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

28377:dck
gene id: 28377:dck
uniprot id: G1KN26
names: Similarity
messages: Belongs to the DCK/DGK family.

28377:LOC100560231
gene id: 28377:LOC100560231
uniprot id: G1KVG1
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

28377:stard3
gene id: 28377:stard3
uniprot id: G1KCA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

28377:chd1
gene id: 28377:chd1
uniprot id: G1KLI0
names: Subcellular Location Annotation
messages: Nucleus

28377:lrrfip2
gene id: 28377:lrrfip2
uniprot id: G1KJL5
names: Similarity
messages: Belongs to the LRRFIP family.

28377:LOC100552777
gene id: 28377:LOC100552777
uniprot id: A0A803TT71
names: Similarity
messages: Belongs to the IUNH family.

28377:lmln
gene id: 28377:lmln
uniprot id: G1KJC1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M8 family.
messages: Binds 1 zinc ion per subunit.

28377:slc6a11
gene id: 28377:slc6a11
uniprot id: G1KJK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

28377:amotl1
gene id: 28377:amotl1
uniprot id: A0A803T240
uniprot id: G1KPF3
names: Similarity
messages: Belongs to the angiomotin family.

28377:taf4
gene id: 28377:taf4
uniprot id: G1KSB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

28377:ppfia3
gene id: 28377:ppfia3
uniprot id: A0A803TVP1
uniprot id: G1KNF5
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

28377:ssrp1
gene id: 28377:ssrp1
uniprot id: A0A803TVB1
uniprot id: G1KGS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

28377:nfix
gene id: 28377:nfix
uniprot id: G1KTH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

28377:npffr2
gene id: 28377:npffr2
uniprot id: A0A803TWI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

28377:tmem106b
gene id: 28377:tmem106b
uniprot id: A0A803SM18
names: Similarity
messages: Belongs to the TMEM106 family.

28377:LOC100567580
gene id: 28377:LOC100567580
uniprot id: A0A803T367
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

28377:xrcc4
gene id: 28377:xrcc4
uniprot id: G1KKY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XRCC4 subfamily.
messages: Nucleus

28377:stard3nl
gene id: 28377:stard3nl
uniprot id: G1KU92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

28377:pdgfd
gene id: 28377:pdgfd
uniprot id: G1KLM4
names: Caution
names: Subunit
messages: Homodimer; disulfide-linked. Interacts with PDGFRB homodimers, and with heterodimers formed by PDGFRA and PDGFRB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:crbn
gene id: 28377:crbn
uniprot id: G1KEF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRBN family.
messages: Nucleus

28377:steap1
gene id: 28377:steap1
uniprot id: G1KRU2
names: Subcellular Location Annotation
messages: Membrane

28377:arhgap26
gene id: 28377:arhgap26
uniprot id: A0A803T7T0
uniprot id: A0A803TYN2
uniprot id: G1KP18
names: Subcellular Location Annotation
messages: cytoskeleton
messages: focal adhesion

28377:dynlt1
gene id: 28377:dynlt1
uniprot id: G1KD68
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

28377:LOC100553824
gene id: 28377:LOC100553824
uniprot id: A0A803TB36
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

28377:fam13a
gene id: 28377:fam13a
uniprot id: A0A803TEU0
uniprot id: A0A803TGX2
uniprot id: G1KNK6
names: Similarity
messages: Belongs to the FAM13 family.

28377:LOC100552964
gene id: 28377:LOC100552964
uniprot id: G1KK45
names: Similarity
messages: Belongs to the cytochrome P450 family.

28377:ell2
gene id: 28377:ell2
uniprot id: G1KMZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

28377:LOC100567906
gene id: 28377:LOC100567906
uniprot id: R4GBC5
names: Function
names: Subcellular Location Annotation
messages: Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.
messages: Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.
messages: Secreted

28377:patl1
gene id: 28377:patl1
uniprot id: G1KFK1
names: Similarity
messages: Belongs to the PAT1 family.

28377:LOC100566148
gene id: 28377:LOC100566148
uniprot id: G1KLZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

28377:igf1
gene id: 28377:igf1
uniprot id: A0A803TEA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

28377:pros1
gene id: 28377:pros1
uniprot id: G1K8T9
names: Caution
names: Function
messages: Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:kctd3
gene id: 28377:kctd3
uniprot id: G1KU80
names: Similarity
messages: Belongs to the KCTD3 family.

28377:kcnj11
gene id: 28377:kcnj11
uniprot id: G1K877
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ11 subfamily.
messages: Membrane

28377:mrpl37
gene id: 28377:mrpl37
uniprot id: G1KPL1
names: Subcellular Location Annotation
messages: Mitochondrion

28377:nkx1-2
gene id: 28377:nkx1-2
uniprot id: G1KVY8
names: Subcellular Location Annotation
messages: Nucleus

28377:rad21
gene id: 28377:rad21
uniprot id: G1KKS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

28377:panx1
gene id: 28377:panx1
uniprot id: G1KPN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

28377:sept11
gene id: 28377:sept11
uniprot id: A0A803SXX3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

28377:vim
gene id: 28377:vim
uniprot id: G1KDR6
names: Function
names: Similarity
messages: Belongs to the intermediate filament family.
messages: Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.

28377:madd
gene id: 28377:madd
uniprot id: A0A803T6I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MADD family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

28377:lrp12
gene id: 28377:lrp12
uniprot id: A0A803TLY6
uniprot id: G1KJE0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:p2ry1
gene id: 28377:p2ry1
uniprot id: G1KL06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:foxi3
gene id: 28377:foxi3
uniprot id: G1KGL5
names: Subcellular Location Annotation
messages: Nucleus

28377:hoxb1
gene id: 28377:hoxb1
uniprot id: A0A803TYE2
names: Subcellular Location Annotation
messages: Nucleus

28377:ucn3
gene id: 28377:ucn3
uniprot id: G1KB15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

28377:kcnk2
gene id: 28377:kcnk2
uniprot id: A0A803T5V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

28377:plppr1
gene id: 28377:plppr1
uniprot id: G1KTW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Cell membrane
messages: May play a role in neurite outgrowth and neurogenesis.
messages: Membrane
messages: neuron projection

28377:yipf2
gene id: 28377:yipf2
uniprot id: G1KQZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

28377:parvb
gene id: 28377:parvb
uniprot id: A0A803SNJ9
uniprot id: G1KXP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

28377:zdhhc23
gene id: 28377:zdhhc23
uniprot id: G1KV57
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

28377:rnpc3
gene id: 28377:rnpc3
uniprot id: G1KAA4
names: Subcellular Location Annotation
messages: Nucleus

28377:usp16
gene id: 28377:usp16
uniprot id: G1K9U0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. USP16 subfamily.
messages: Homotetramer.
messages: Nucleus
messages: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.
messages: The UBP-type zinc finger binds 3 zinc ions that form a pair of cross-braced ring fingers encapsulated within a third zinc finger in the primary structure. It recognizes the C-terminal tail of free ubiquitin.

28377:akt1
gene id: 28377:akt1
uniprot id: G1KLB6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

28377:ubl3
gene id: 28377:ubl3
uniprot id: G1KEN4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28377:galnt2
gene id: 28377:galnt2
uniprot id: G1K9H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

28377:p2rx3
gene id: 28377:p2rx3
uniprot id: G1KGM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

28377:wdfy2
gene id: 28377:wdfy2
uniprot id: G1KLW1
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

28377:dok3
gene id: 28377:dok3
uniprot id: G1KEU3
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

28377:gabbr2
gene id: 28377:gabbr2
uniprot id: G1KAG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

28377:guf1
gene id: 28377:guf1
uniprot id: G1KG38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

28377:foxa1
gene id: 28377:foxa1
uniprot id: A0A803TSG9
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC100558074
gene id: 28377:LOC100558074
uniprot id: G1KAU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

28377:axl
gene id: 28377:axl
uniprot id: H9G8C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

28377:hoxc13
gene id: 28377:hoxc13
uniprot id: G1KKK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

28377:amigo2
gene id: 28377:amigo2
uniprot id: G1K9S7
names: Similarity
messages: Belongs to the immunoglobulin superfamily. AMIGO family.

28377:mrpl3
gene id: 28377:mrpl3
uniprot id: G1K9Q3
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

28377:LOC100564770
gene id: 28377:LOC100564770
uniprot id: A0A803T626
uniprot id: R4G946
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28377:zic1
gene id: 28377:zic1
uniprot id: G1KFX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

28377:LOC100561092
gene id: 28377:LOC100561092
uniprot id: G1KPR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

28377:irf6
gene id: 28377:irf6
uniprot id: G1KEV4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

28377:rpl3
gene id: 28377:rpl3
uniprot id: G1KH03
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

28377:myog
gene id: 28377:myog
uniprot id: G1KD71
names: Subcellular Location Annotation
messages: Nucleus

28377:clp1
gene id: 28377:clp1
uniprot id: G1KG72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex. Component of pre-mRNA cleavage complex II (CF-II).
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

28377:glra3
gene id: 28377:glra3
uniprot id: G1KEG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

28377:atp7b
gene id: 28377:atp7b
uniprot id: G1KT84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

28377:cnrip1
gene id: 28377:cnrip1
uniprot id: G1K8Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

28377:fga
gene id: 28377:fga
uniprot id: G1KRE2
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

28377:pfkl
gene id: 28377:pfkl
uniprot id: G1KID2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:galr2
gene id: 28377:galr2
uniprot id: A0A803U085
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

28377:cnpy2
gene id: 28377:cnpy2
uniprot id: G1KGV7
names: Similarity
messages: Belongs to the canopy family.

28377:pdk2
gene id: 28377:pdk2
uniprot id: G1KE56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

28377:LOC100559827
gene id: 28377:LOC100559827
uniprot id: G1KIC7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
messages: Heterodimer of an alpha and a beta subunit.

28377:sqle
gene id: 28377:sqle
uniprot id: G1KJU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane

28377:dnajc24
gene id: 28377:dnajc24
uniprot id: A0A803TJA5
names: Similarity
messages: Belongs to the DPH4 family.

28377:cd180
gene id: 28377:cd180
uniprot id: G1KSD5
names: Similarity
messages: Belongs to the Toll-like receptor family.

28377:LOC100563080
gene id: 28377:LOC100563080
uniprot id: G1KR33
names: Subcellular Location Annotation
messages: Membrane

28377:uxt
gene id: 28377:uxt
uniprot id: G1KD45
names: Similarity
messages: Belongs to the UXT family.

28377:tmed2
gene id: 28377:tmed2
uniprot id: A0A803SS45
uniprot id: A0A803TVV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

28377:araf
gene id: 28377:araf
uniprot id: G1KL07
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

28377:LOC100556582
gene id: 28377:LOC100556582
uniprot id: G1K9X4
names: Similarity
messages: Belongs to the CLCR family.

28377:apom
gene id: 28377:apom
uniprot id: A0A803U0U4
uniprot id: G1KM70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
messages: Interacts with LRP2; LRP2 mediates APOM renal uptake and subsequent lysosomal degradation.
messages: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.
messages: Secreted

28377:snx4
gene id: 28377:snx4
uniprot id: R4GB33
names: Similarity
messages: Belongs to the sorting nexin family.

28377:LOC100562920
gene id: 28377:LOC100562920
uniprot id: A0A803T106
uniprot id: G1KCM0
names: Similarity
messages: Belongs to the serpin family.

28377:mrpl32
gene id: 28377:mrpl32
uniprot id: A0A803SVE8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

28377:tmtc3
gene id: 28377:tmtc3
uniprot id: G1KLD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

28377:LOC100565422
gene id: 28377:LOC100565422
uniprot id: G1KG34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

28377:LOC100561108
gene id: 28377:LOC100561108
uniprot id: G1KM68
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28377:tbce
gene id: 28377:tbce
uniprot id: R4GAP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

28377:tmem33
gene id: 28377:tmem33
uniprot id: G1KLT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

28377:pcmtd2
gene id: 28377:pcmtd2
uniprot id: A0A803SSB3
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

28377:b4galt4
gene id: 28377:b4galt4
uniprot id: G1KCW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

28377:haus1
gene id: 28377:haus1
uniprot id: G1KMM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

28377:LOC100557661
gene id: 28377:LOC100557661
uniprot id: G1KDK9
names: Subcellular Location Annotation
messages: Cytoplasm

28377:LOC100567830
gene id: 28377:LOC100567830
uniprot id: G1KN48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

28377:sfrp5
gene id: 28377:sfrp5
uniprot id: G1KBI3
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:LOC100559642
gene id: 28377:LOC100559642
uniprot id: G1KIT2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28377:dfna5
gene id: 28377:dfna5
uniprot id: G1KNI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

28377:rgs7bp
gene id: 28377:rgs7bp
uniprot id: G1KRB0
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

28377:aifm2
gene id: 28377:aifm2
uniprot id: G1KUD7
names: Similarity
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.

28377:dnajb12
gene id: 28377:dnajb12
uniprot id: A0A803TMX9
uniprot id: G1K918
names: Subcellular Location Annotation
messages: Membrane

28377:slc24a2
gene id: 28377:slc24a2
uniprot id: G1KU78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

28377:st6gal1
gene id: 28377:st6gal1
uniprot id: A0A803TN77
uniprot id: E4ZFG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

28377:fam19a4
gene id: 28377:fam19a4
uniprot id: R4G9F8
names: Similarity
messages: Belongs to the TAFA family.

28377:ppdpf
gene id: 28377:ppdpf
uniprot id: G1KEX0
names: Similarity
messages: Belongs to the PPDPF family.

28377:fitm2
gene id: 28377:fitm2
uniprot id: G1KT26
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:plaa
gene id: 28377:plaa
uniprot id: G1KU18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PLAP family.
messages: Cytoplasm

28377:timp2
gene id: 28377:timp2
uniprot id: A0A803SMV3
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

28377:gpr87
gene id: 28377:gpr87
uniprot id: G1KVB4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:scin
gene id: 28377:scin
uniprot id: A0A803T8A7
uniprot id: G1KNZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: cytoskeleton
messages: podosome

28377:dnm1l
gene id: 28377:dnm1l
uniprot id: A0A803T7M5
uniprot id: G1KMD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: Endomembrane system
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: clathrin-coated pit
messages: cytosol
messages: synaptic vesicle membrane

28377:gstz1
gene id: 28377:gstz1
uniprot id: G1KTM3
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

28377:LOC100564439
gene id: 28377:LOC100564439
uniprot id: G1KRK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:anapc13
gene id: 28377:anapc13
uniprot id: A0A803TP20
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

28377:mael
gene id: 28377:mael
uniprot id: R4GC38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the maelstrom family.
messages: Nucleus
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage.

28377:LOC100560181
gene id: 28377:LOC100560181
uniprot id: G1KMP9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

28377:trh
gene id: 28377:trh
uniprot id: A0A803TI60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRH family.
messages: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
messages: Secreted

28377:kcna4
gene id: 28377:kcna4
uniprot id: G1KA04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: axon

28377:ripply2
gene id: 28377:ripply2
uniprot id: A0A803TKI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

28377:LOC100556256
gene id: 28377:LOC100556256
uniprot id: A0A803T3S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Membrane
messages: Microsome membrane

28377:atp1b3
gene id: 28377:atp1b3
uniprot id: G1KDL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

28377:atl2
gene id: 28377:atl2
uniprot id: A0A803TLX0
uniprot id: G1KQ36
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

28377:zdhhc17
gene id: 28377:zdhhc17
uniprot id: G1KFQ3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

28377:acox1
gene id: 28377:acox1
uniprot id: A0A803TM37
uniprot id: G1KH33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

28377:p2rx7
gene id: 28377:p2rx7
uniprot id: H9GQC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P2X receptor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

28377:pex1
gene id: 28377:pex1
uniprot id: G1KR45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

28377:atp9b
gene id: 28377:atp9b
uniprot id: A0A803T860
uniprot id: G1K8V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

28377:LOC100554943
gene id: 28377:LOC100554943
uniprot id: G1KP03
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

28377:pou3f2
gene id: 28377:pou3f2
uniprot id: G1KXS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

28377:abcd3
gene id: 28377:abcd3
uniprot id: G1KDK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

28377:inhbb
gene id: 28377:inhbb
uniprot id: R4GDL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

28377:akap8l
gene id: 28377:akap8l
uniprot id: G1KTQ8
names: Similarity
messages: Belongs to the AKAP95 family.

28377:stag1
gene id: 28377:stag1
uniprot id: G1KGT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

28377:LOC100556634
gene id: 28377:LOC100556634
uniprot id: A0A803SZB0
uniprot id: G1KMP7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

28377:sh3glb1
gene id: 28377:sh3glb1
uniprot id: A0A803TCX9
uniprot id: G1K9U9
uniprot id: R4GCT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Mitochondrion outer membrane

28377:crls1
gene id: 28377:crls1
uniprot id: A0A803TMG6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

28377:vill
gene id: 28377:vill
uniprot id: G1KE69
names: Similarity
messages: Belongs to the villin/gelsolin family.

28377:sdpr
gene id: 28377:sdpr
uniprot id: A0A803TEC5
uniprot id: G1KFN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

28377:fam168b
gene id: 28377:fam168b
uniprot id: G1KDB1
names: Similarity
messages: Belongs to the FAM168 family.

28377:ppil1
gene id: 28377:ppil1
uniprot id: G1KKA8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

28377:enpp3
gene id: 28377:enpp3
uniprot id: G1K9M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Secreted

28377:ngb
gene id: 28377:ngb
uniprot id: A0A803TPD9
names: Similarity
messages: Belongs to the globin family.

28377:adcy6
gene id: 28377:adcy6
uniprot id: G1KHZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

28377:c7
gene id: 28377:c7
uniprot id: G1KJY2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:hdac3
gene id: 28377:hdac3
uniprot id: G1KLP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
messages: Nucleus

28377:qtrt2
gene id: 28377:qtrt2
uniprot id: G1KJG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane
messages: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

28377:ccl20
gene id: 28377:ccl20
uniprot id: R4G9F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

28377:itpk1
gene id: 28377:itpk1
uniprot id: G1KI84
names: Similarity
messages: Belongs to the ITPK1 family.

28377:slc20a2
gene id: 28377:slc20a2
uniprot id: A0A803SKW2
uniprot id: G1KIP7
uniprot id: R4G9N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

28377:ctsl
gene id: 28377:ctsl
uniprot id: A0A803TVI0
names: Similarity
messages: Belongs to the peptidase C1 family.

28377:pnn
gene id: 28377:pnn
uniprot id: G1KRV3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pinin family.
messages: Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.
messages: Nucleus speckle
messages: desmosome

28377:slc6a15
gene id: 28377:slc6a15
uniprot id: G1KKT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily.
messages: Membrane

28377:LOC100552076
gene id: 28377:LOC100552076
uniprot id: R4G9U3
names: Similarity
messages: Belongs to the intermediate filament family.

28377:h3f3b
gene id: 28377:h3f3b
uniprot id: G1KGC9
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

28377:coro1b
gene id: 28377:coro1b
uniprot id: G1KHU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat coronin family.
messages: Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction.
messages: stress fiber

28377:LOC103279038
gene id: 28377:LOC103279038
uniprot id: R4G9B2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

28377:elk3
gene id: 28377:elk3
uniprot id: G1KP19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

28377:slc6a19
gene id: 28377:slc6a19
uniprot id: G1K9X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

28377:LOC100557882
gene id: 28377:LOC100557882
uniprot id: A0A803T8P3
uniprot id: G1KEM0
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

28377:sh3yl1
gene id: 28377:sh3yl1
uniprot id: L7MZM8
names: Similarity
messages: Belongs to the SH3YL1 family.

28377:rab21
gene id: 28377:rab21
uniprot id: G1KGJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cleavage furrow
messages: Cytoplasmic vesicle membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: neuron projection
messages: trans-Golgi network

28377:leprot
gene id: 28377:leprot
uniprot id: G1KIC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

28377:LOC100564496
gene id: 28377:LOC100564496
uniprot id: R4GC31
names: Subcellular Location Annotation
messages: Secreted

28377:sgsm3
gene id: 28377:sgsm3
uniprot id: G1KE59
names: Similarity
messages: Belongs to the small G protein signaling modulator family.

28377:opn3
gene id: 28377:opn3
uniprot id: G1KBW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

28377:exoc7
gene id: 28377:exoc7
uniprot id: A0A803TV19
uniprot id: G1KHD7
names: Function
names: Similarity
messages: Belongs to the EXO70 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

28377:nr4a1
gene id: 28377:nr4a1
uniprot id: G1KT44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR4 subfamily.
messages: Cytoplasm
messages: Nucleus

28377:LOC100562367
gene id: 28377:LOC100562367
uniprot id: G1KLK9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

28377:ppp1r21
gene id: 28377:ppp1r21
uniprot id: G1KPS2
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

28377:kdm4c
gene id: 28377:kdm4c
uniprot id: G1KCZ9
names: Similarity
messages: Belongs to the JHDM3 histone demethylase family.

28377:rft1
gene id: 28377:rft1
uniprot id: G1KHQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: May be involved in N-linked oligosaccharide assembly.
messages: Membrane

28377:tk1
gene id: 28377:tk1
uniprot id: C3VAL3
uniprot id: G1KT08
names: Similarity
messages: Belongs to the thymidine kinase family.

28377:dlgap4
gene id: 28377:dlgap4
uniprot id: G1KJD8
names: Similarity
messages: Belongs to the SAPAP family.

28377:tfeb
gene id: 28377:tfeb
uniprot id: G1KB16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

28377:fmod
gene id: 28377:fmod
uniprot id: G1KAB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis.
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to type I and type II collagen.
messages: extracellular matrix

28377:desi1
gene id: 28377:desi1
uniprot id: G1KCY7
names: Similarity
messages: Belongs to the DeSI family.

28377:mrps33
gene id: 28377:mrps33
uniprot id: A0A803TD31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

28377:denr
gene id: 28377:denr
uniprot id: H9GMV2
names: Similarity
messages: Belongs to the DENR family.

28377:LOC100556641
gene id: 28377:LOC100556641
uniprot id: G1KN92
names: Similarity
messages: Belongs to the PHAF1 family.

28377:smad9
gene id: 28377:smad9
uniprot id: G1KCU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

28377:stxbp5
gene id: 28377:stxbp5
uniprot id: G1KGA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

28377:npy
gene id: 28377:npy
uniprot id: G1KNP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

28377:kcnb2
gene id: 28377:kcnb2
uniprot id: G1KYA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Perikaryon

28377:smim15
gene id: 28377:smim15
uniprot id: G1KI83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

28377:cnksr3
gene id: 28377:cnksr3
uniprot id: G1KE49
names: Similarity
messages: Belongs to the CNKSR family.

28377:stat1
gene id: 28377:stat1
uniprot id: G1KF84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

28377:trappc6b
gene id: 28377:trappc6b
uniprot id: G1KRS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

28377:alox5ap
gene id: 28377:alox5ap
uniprot id: A0A803STA1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

28377:anapc11
gene id: 28377:anapc11
uniprot id: A0A803TAQ8
names: Similarity
messages: Belongs to the RING-box family.

28377:trmt11
gene id: 28377:trmt11
uniprot id: G1KAB8
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

28377:lrrc16a
gene id: 28377:lrrc16a
uniprot id: G1K9V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

28377:prkg2
gene id: 28377:prkg2
uniprot id: G1KJX1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

28377:pwp2
gene id: 28377:pwp2
uniprot id: G1KUF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

28377:fam19a2
gene id: 28377:fam19a2
uniprot id: R4GBI7
names: Similarity
messages: Belongs to the TAFA family.

28377:LOC100553624
gene id: 28377:LOC100553624
uniprot id: G1K9T2
uniprot id: R4GAE4
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

28377:dcstamp
gene id: 28377:dcstamp
uniprot id: G1KJ52
names: Subcellular Location Annotation
messages: Membrane

28377:arpc4
gene id: 28377:arpc4
uniprot id: G1KJF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

28377:rpia
gene id: 28377:rpia
uniprot id: A0A803T954
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

28377:nfasc
gene id: 28377:nfasc
uniprot id: G1KP86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

28377:utp15
gene id: 28377:utp15
uniprot id: G1KIV1
names: Subcellular Location Annotation
messages: nucleolus

28377:sfxn2
gene id: 28377:sfxn2
uniprot id: G1KCP7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

28377:nsun7
gene id: 28377:nsun7
uniprot id: G1KLL8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:ralb
gene id: 28377:ralb
uniprot id: A0A803SRY0
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

28377:ctso
gene id: 28377:ctso
uniprot id: G1KT79
names: Similarity
messages: Belongs to the peptidase C1 family.

28377:oprm1
gene id: 28377:oprm1
uniprot id: G1KE66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: axon
messages: dendrite

28377:adrm1
gene id: 28377:adrm1
uniprot id: A0A803TX70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADRM1 family.
messages: Cytoplasm
messages: Nucleus

28377:eif3d
gene id: 28377:eif3d
uniprot id: G1KSG6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

28377:sparc
gene id: 28377:sparc
uniprot id: A0A803T5M1
uniprot id: G1KJH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
messages: Belongs to the SPARC family.
messages: Membrane
messages: basement membrane

28377:cpn1
gene id: 28377:cpn1
uniprot id: G1KCP4
names: Similarity
messages: Belongs to the peptidase M14 family.

28377:pgap3
gene id: 28377:pgap3
uniprot id: G1KC81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Golgi apparatus membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Membrane

28377:fam161a
gene id: 28377:fam161a
uniprot id: G1KE87
names: Similarity
messages: Belongs to the FAM161 family.

28377:LOC100552666
gene id: 28377:LOC100552666
uniprot id: H9GLW2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

28377:dusp9
gene id: 28377:dusp9
uniprot id: G1KIJ6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

28377:scube2
gene id: 28377:scube2
uniprot id: A0A803TGY9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:tmem135
gene id: 28377:tmem135
uniprot id: A0A803T9V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM135 family.
messages: Membrane
messages: Peroxisome membrane

28377:LOC100558870
gene id: 28377:LOC100558870
uniprot id: R4GB63
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.
messages: perinuclear region

28377:akap5
gene id: 28377:akap5
uniprot id: G1KXM8
names: Subcellular Location Annotation
messages: Membrane

28377:slc15a1
gene id: 28377:slc15a1
uniprot id: A0A803T6J5
uniprot id: G1KST4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

28377:il6
gene id: 28377:il6
uniprot id: R4GCE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

28377:anxa1
gene id: 28377:anxa1
uniprot id: G1KLU8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the annexin family.
messages: Cell membrane
messages: Cytoplasm
messages: Lateral cell membrane
messages: Membrane
messages: Nucleus
messages: The full-length protein can bind eight Ca(2+) ions via the annexin repeats. Calcium binding causes a major conformation change that modifies dimer contacts and leads to surface exposure of the N-terminal phosphorylation sites; in the absence of Ca(2+), these sites are buried in the interior of the protein core. The N-terminal region becomes disordered in response to calcium-binding.
messages: cilium

28377:zeb2
gene id: 28377:zeb2
uniprot id: G1KZE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.
messages: Nucleus

28377:LOC100552579
gene id: 28377:LOC100552579
uniprot id: G1KP83
names: Similarity
messages: Belongs to the histone H3 family.

28377:LOC100561746
gene id: 28377:LOC100561746
uniprot id: A0A803SSG8
names: Similarity
messages: Belongs to the FBPase class 1 family.

28377:ppp4r2
gene id: 28377:ppp4r2
uniprot id: G1KQF0
names: Similarity
messages: Belongs to the PPP4R2 family.

28377:LOC100567438
gene id: 28377:LOC100567438
uniprot id: G1KDQ0
names: Subcellular Location Annotation
messages: Nucleus

28377:myoz2
gene id: 28377:myoz2
uniprot id: G1KNR7
names: Similarity
messages: Belongs to the myozenin family.

28377:oxr1
gene id: 28377:oxr1
uniprot id: A0A803SQG2
uniprot id: G1KJJ0
names: Similarity
messages: Belongs to the OXR1 family.

28377:cndp1
gene id: 28377:cndp1
uniprot id: G1KC31
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

28377:gucy1a3
gene id: 28377:gucy1a3
uniprot id: G1KTE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

28377:steap4
gene id: 28377:steap4
uniprot id: G1KRV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

28377:kynu
gene id: 28377:kynu
uniprot id: A0A803TNS6
uniprot id: G1KBM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:LOC100564432
gene id: 28377:LOC100564432
uniprot id: R4GDE7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

28377:irak4
gene id: 28377:irak4
uniprot id: G1KBF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

28377:arf3
gene id: 28377:arf3
uniprot id: G1KHJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

28377:ston2
gene id: 28377:ston2
uniprot id: A0A803TGN7
uniprot id: G1KTX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating.
messages: Belongs to the Stoned B family.
messages: Cytoplasm
messages: synaptosome

28377:osbpl5
gene id: 28377:osbpl5
uniprot id: G1K896
names: Similarity
messages: Belongs to the OSBP family.

28377:LOC103278032
gene id: 28377:LOC103278032
uniprot id: G1KLC8
names: Subcellular Location Annotation
messages: Secreted

28377:calb1
gene id: 28377:calb1
uniprot id: G1KK84
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.

28377:borcs7
gene id: 28377:borcs7
uniprot id: A0A803T8T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS7 family.
messages: Membrane

28377:foxj1
gene id: 28377:foxj1
uniprot id: G1KHE4
names: Subcellular Location Annotation
messages: Nucleus

28377:dlst
gene id: 28377:dlst
uniprot id: G1KT20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

28377:ano7
gene id: 28377:ano7
uniprot id: G1K9Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

28377:rab4b
gene id: 28377:rab4b
uniprot id: H9GK45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

28377:LOC100555255
gene id: 28377:LOC100555255
uniprot id: G1KU55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

28377:faim2
gene id: 28377:faim2
uniprot id: G1KHS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

28377:LOC100561212
gene id: 28377:LOC100561212
uniprot id: A0A803T7U3
uniprot id: A0A803TUG7
uniprot id: G1KWL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

28377:LOC107982237
gene id: 28377:LOC107982237
uniprot id: G1KPX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

28377:otulin
gene id: 28377:otulin
uniprot id: G1K8E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

28377:sptlc3
gene id: 28377:sptlc3
uniprot id: G1KZA9
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

28377:c4h6orf89
gene id: 28377:c4h6orf89
uniprot id: G1KSX6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

28377:spats2l
gene id: 28377:spats2l
uniprot id: G1KS29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPATS2 family.
messages: Cytoplasm

28377:prtfdc1
gene id: 28377:prtfdc1
uniprot id: A0A803SMR0
uniprot id: A0A803TKL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

28377:lum
gene id: 28377:lum
uniprot id: A0A803SSI0
uniprot id: G1KM64
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to laminin.
messages: extracellular matrix

28377:tp53rk
gene id: 28377:tp53rk
uniprot id: G1KSY3
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

28377:epyc
gene id: 28377:epyc
uniprot id: G1KM57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
messages: extracellular matrix

28377:nr2c2
gene id: 28377:nr2c2
uniprot id: G1KM19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

28377:LOC100564129
gene id: 28377:LOC100564129
uniprot id: G1KFF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

28377:ip6k3
gene id: 28377:ip6k3
uniprot id: A0A803TP65
uniprot id: G1KS75
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

28377:iars
gene id: 28377:iars
uniprot id: G1KJ05
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

28377:sugct
gene id: 28377:sugct
uniprot id: G1KU60
names: Similarity
messages: Belongs to the CoA-transferase III family.

28377:cav1
gene id: 28377:cav1
uniprot id: G1KFH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Membrane raft
messages: caveola

28377:inip
gene id: 28377:inip
uniprot id: A0A803TA35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus

28377:trim16
gene id: 28377:trim16
uniprot id: G1KU47
names: Similarity
messages: Belongs to the ohanin/vespryn family.

28377:st7
gene id: 28377:st7
uniprot id: A0A803U0K8
uniprot id: G1KHG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

28377:LOC100560052
gene id: 28377:LOC100560052
uniprot id: A0A803SSH4
uniprot id: G1K997
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

28377:st3gal6
gene id: 28377:st3gal6
uniprot id: A0A803TMM1
uniprot id: G1KKN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

28377:myh7b
gene id: 28377:myh7b
uniprot id: L7MZS4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

28377:LOC100556963
gene id: 28377:LOC100556963
uniprot id: G1KCZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

28377:insig1
gene id: 28377:insig1
uniprot id: G1KKP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

28377:LOC100552698
gene id: 28377:LOC100552698
uniprot id: A0A803TFW8
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

28377:rfx1
gene id: 28377:rfx1
uniprot id: A0A803SWQ3
uniprot id: A0A803TI98
uniprot id: A0A803TNS8
uniprot id: G1KRG3
names: Subcellular Location Annotation
messages: Nucleus

28377:ube2k
gene id: 28377:ube2k
uniprot id: G1KL25
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

28377:ing3
gene id: 28377:ing3
uniprot id: G1KG43
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

28377:ninj2
gene id: 28377:ninj2
uniprot id: A0A803TMA4
uniprot id: G1K861
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

28377:kcnj8
gene id: 28377:kcnj8
uniprot id: G1KTJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

28377:fgd6
gene id: 28377:fgd6
uniprot id: G1KN38
names: Subcellular Location Annotation
messages: cytoskeleton

28377:cul2
gene id: 28377:cul2
uniprot id: A0A803U060
uniprot id: G1K8W4
names: Similarity
messages: Belongs to the cullin family.

28377:mfsd14a
gene id: 28377:mfsd14a
uniprot id: G1KC18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

28377:ssbp1
gene id: 28377:ssbp1
uniprot id: G1KLA3
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

28377:serpina10
gene id: 28377:serpina10
uniprot id: G1KCG5
names: Similarity
messages: Belongs to the serpin family.

28377:s1pr5
gene id: 28377:s1pr5
uniprot id: G1KS14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

28377:LOC103278531
gene id: 28377:LOC103278531
uniprot id: A0A803TAG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Nucleus

28377:pex2
gene id: 28377:pex2
uniprot id: G1KNL9
names: Function
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.
messages: Somewhat implicated in the biogenesis of peroxisomes.

28377:LOC100554292
gene id: 28377:LOC100554292
uniprot id: G1KLF4
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

28377:hnf4a
gene id: 28377:hnf4a
uniprot id: G1KT65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

28377:slc25a39
gene id: 28377:slc25a39
uniprot id: A0A803SR27
uniprot id: G1KTR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

28377:LOC100564200
gene id: 28377:LOC100564200
uniprot id: A0A803SR03
uniprot id: G1KUG5
names: Similarity
messages: Belongs to the intermediate filament family.

28377:figf
gene id: 28377:figf
uniprot id: G1KMB4
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

28377:gclm
gene id: 28377:gclm
uniprot id: G1KDY6
names: Similarity
names: Subunit
messages: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
messages: Heterodimer of a catalytic heavy chain and a regulatory light chain.

28377:LOC100557734
gene id: 28377:LOC100557734
uniprot id: G1KE38
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:igfbp1
gene id: 28377:igfbp1
uniprot id: G1KHC0
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:pde6h
gene id: 28377:pde6h
uniprot id: G1KUR7
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

28377:med23
gene id: 28377:med23
uniprot id: G1K9V6
uniprot id: R4G9H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 23 family.
messages: Nucleus

28377:gjd2
gene id: 28377:gjd2
uniprot id: G1K942
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

28377:pard3
gene id: 28377:pard3
uniprot id: A0A803SRN1
uniprot id: G1K955
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

28377:pth2r
gene id: 28377:pth2r
uniprot id: G1KKX5
names: Subcellular Location Annotation
messages: Membrane

28377:pld3
gene id: 28377:pld3
uniprot id: H9G710
names: Similarity
messages: Belongs to the phospholipase D family.

28377:elmo1
gene id: 28377:elmo1
uniprot id: G1KUB6
names: Subcellular Location Annotation
messages: Cytoplasm

28377:mb
gene id: 28377:mb
uniprot id: G1KST1
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

28377:LOC100552581
gene id: 28377:LOC100552581
uniprot id: G1KEP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

28377:bace2
gene id: 28377:bace2
uniprot id: G1KET0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Membrane

28377:cnn3
gene id: 28377:cnn3
uniprot id: G1KD90
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

28377:pik3r3
gene id: 28377:pik3r3
uniprot id: A0A803T5A6
uniprot id: G1KRT8
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

28377:c3h11orf54
gene id: 28377:c3h11orf54
uniprot id: G1KQ09
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

28377:ap4b1
gene id: 28377:ap4b1
uniprot id: A0A803T7N3
uniprot id: G1KAG2
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

28377:smarca5
gene id: 28377:smarca5
uniprot id: G1KBM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

28377:c3h2orf49
gene id: 28377:c3h2orf49
uniprot id: A0A803TVW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ashwin family.
messages: Nucleus

28377:ppp2r5e
gene id: 28377:ppp2r5e
uniprot id: A0A803SLS6
uniprot id: G1KS59
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

28377:ntrk2
gene id: 28377:ntrk2
uniprot id: G1K941
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

28377:csad
gene id: 28377:csad
uniprot id: G1KG61
names: Similarity
messages: Belongs to the group II decarboxylase family.

28377:drd3
gene id: 28377:drd3
uniprot id: G1KJF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation.
messages: Membrane

28377:tef
gene id: 28377:tef
uniprot id: A0A803TMH8
uniprot id: G1KD66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

28377:rsbn1
gene id: 28377:rsbn1
uniprot id: G1K8C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

28377:wdr48
gene id: 28377:wdr48
uniprot id: G1KIZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR48 family.
messages: Endosome
messages: Late endosome

28377:ppp1r12b
gene id: 28377:ppp1r12b
uniprot id: A0A803T4E8
uniprot id: G1KC84
uniprot id: R4GAW3
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.

28377:gtpbp1
gene id: 28377:gtpbp1
uniprot id: A0A803TWY0
uniprot id: G1KHD5
names: Function
messages: Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity.

28377:ano10
gene id: 28377:ano10
uniprot id: A0A803SMN9
uniprot id: A0A803T8K0
uniprot id: G1KQK7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:rap2a
gene id: 28377:rap2a
uniprot id: A0A803TZK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

28377:entpd5
gene id: 28377:entpd5
uniprot id: G1KSD8
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

28377:LOC100557806
gene id: 28377:LOC100557806
uniprot id: A0A803SV69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

28377:znf330
gene id: 28377:znf330
uniprot id: G1KB20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOA36 family.
messages: nucleolus

28377:grk6
gene id: 28377:grk6
uniprot id: A0A803TNB1
uniprot id: G1KF64
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

28377:golm1
gene id: 28377:golm1
uniprot id: G1K8H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

28377:n4bp3
gene id: 28377:n4bp3
uniprot id: G1KFJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N4BP3 family.
messages: Cytoplasmic vesicle
messages: Vesicle
messages: axon
messages: dendrite

28377:harbi1
gene id: 28377:harbi1
uniprot id: G1KCG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

28377:sts
gene id: 28377:sts
uniprot id: A0A803TTR6
uniprot id: G1K8G6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

28377:phkb
gene id: 28377:phkb
uniprot id: A0A803SMZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.

28377:ppp1r10
gene id: 28377:ppp1r10
uniprot id: G1KKH3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers.

28377:gskip
gene id: 28377:gskip
uniprot id: A0A803TYN5
names: Similarity
messages: Belongs to the GSKIP family.

28377:hoxb9
gene id: 28377:hoxb9
uniprot id: A0A803T461
uniprot id: A0A803TE50
uniprot id: A0A803TQC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

28377:mccc2
gene id: 28377:mccc2
uniprot id: G1KJJ7
names: Similarity
messages: Belongs to the AccD/PCCB family.

28377:dhfr
gene id: 28377:dhfr
uniprot id: G1KK77
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

28377:cp
gene id: 28377:cp
uniprot id: G1KGN3
names: Similarity
messages: Belongs to the multicopper oxidase family.

28377:igf2bp1
gene id: 28377:igf2bp1
uniprot id: G1KF72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Nucleus
messages: filopodium
messages: growth cone
messages: lamellipodium
messages: perinuclear region

28377:slc35d2
gene id: 28377:slc35d2
uniprot id: A0A803SMD6
names: Subcellular Location Annotation
messages: Membrane

28377:cdc42ep1
gene id: 28377:cdc42ep1
uniprot id: G1KRM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

28377:kcnh8
gene id: 28377:kcnh8
uniprot id: A0A803TVZ9
uniprot id: G1K854
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

28377:rnpep
gene id: 28377:rnpep
uniprot id: G1KCJ3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

28377:dpy19l1
gene id: 28377:dpy19l1
uniprot id: A0A803SQ63
uniprot id: G1KGN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

28377:psmb1
gene id: 28377:psmb1
uniprot id: G1KAZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

28377:pnpt1
gene id: 28377:pnpt1
uniprot id: G1KCA1
names: Similarity
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.

28377:ccna1
gene id: 28377:ccna1
uniprot id: A0A803SQ41
uniprot id: G1KCT3
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

28377:mylk
gene id: 28377:mylk
uniprot id: G1KKG2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

28377:pcnx1
gene id: 28377:pcnx1
uniprot id: G1KD95
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:LOC100567846
gene id: 28377:LOC100567846
uniprot id: G1KGG3
names: Similarity
messages: Belongs to the ohanin/vespryn family.

28377:ccdc65
gene id: 28377:ccdc65
uniprot id: G1KHL0
names: Subcellular Location Annotation
names: Subunit
messages: Component of the nexin-dynein regulatory complex (N-DRC).
messages: flagellum axoneme

28377:LOC100563146
gene id: 28377:LOC100563146
uniprot id: A0A803T5K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Mitochondrion intermembrane space

28377:alg10
gene id: 28377:alg10
uniprot id: A0A803TBB7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:tmem106a
gene id: 28377:tmem106a
uniprot id: G1KNJ9
names: Similarity
messages: Belongs to the TMEM106 family.

28377:rpl7
gene id: 28377:rpl7
uniprot id: G1KPV4
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

28377:pigx
gene id: 28377:pigx
uniprot id: A0A803THV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis.

28377:LOC100565025
gene id: 28377:LOC100565025
uniprot id: G1KMU6
names: Similarity
messages: Belongs to the cytochrome P450 family.

28377:aldh1a1
gene id: 28377:aldh1a1
uniprot id: G1KMC0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

28377:matn4
gene id: 28377:matn4
uniprot id: G1KM62
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:slc1a2
gene id: 28377:slc1a2
uniprot id: A0A803T2F3
uniprot id: G1KCV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

28377:pik3c2b
gene id: 28377:pik3c2b
uniprot id: G1KGS9
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

28377:LOC100567184
gene id: 28377:LOC100567184
uniprot id: A0A803TQW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:rnh1
gene id: 28377:rnh1
uniprot id: G1KQE3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Forms high-affinity heterodimers with RNASE1, ANG and RNASE2.
messages: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis.

28377:LOC103281183
gene id: 28377:LOC103281183
uniprot id: A0A803TUC5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28377:lpin2
gene id: 28377:lpin2
uniprot id: A0A803T0N6
uniprot id: G1KIM5
names: Similarity
messages: Belongs to the lipin family.

28377:nsa2
gene id: 28377:nsa2
uniprot id: A0A803TW35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

28377:st13
gene id: 28377:st13
uniprot id: G1KDW2
names: Similarity
messages: Belongs to the FAM10 family.

28377:mrpl18
gene id: 28377:mrpl18
uniprot id: G1KCN2
names: Similarity
messages: Belongs to the universal ribosomal protein uL18 family.

28377:csrnp2
gene id: 28377:csrnp2
uniprot id: G1KMA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

28377:arhgef7
gene id: 28377:arhgef7
uniprot id: A0A803T6B1
uniprot id: G1KF97
names: Subcellular Location Annotation
messages: lamellipodium

28377:sap130
gene id: 28377:sap130
uniprot id: G1KDS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

28377:itga2
gene id: 28377:itga2
uniprot id: G1KCG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

28377:cnpy1
gene id: 28377:cnpy1
uniprot id: A0A803T698
uniprot id: A0A803TSP0
uniprot id: G1KKQ7
names: Similarity
messages: Belongs to the canopy family.

28377:slitrk3
gene id: 28377:slitrk3
uniprot id: G1KU71
names: Similarity
messages: Belongs to the SLITRK family.

28377:chst11
gene id: 28377:chst11
uniprot id: G1KRU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

28377:syndig1l
gene id: 28377:syndig1l
uniprot id: G1KSM4
names: Similarity
messages: Belongs to the CD225/Dispanin family.

28377:nipa2
gene id: 28377:nipa2
uniprot id: G1KMN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

28377:chst15
gene id: 28377:chst15
uniprot id: G1KU30
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

28377:atp2a2
gene id: 28377:atp2a2
uniprot id: H9GN00
uniprot id: R4GAT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

28377:b4galnt4
gene id: 28377:b4galnt4
uniprot id: G1KNR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

28377:gjd4
gene id: 28377:gjd4
uniprot id: A0A803TXK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

28377:tsfm
gene id: 28377:tsfm
uniprot id: G1KN68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion

28377:ccng2
gene id: 28377:ccng2
uniprot id: G1KLY4
names: Similarity
messages: Belongs to the cyclin family.

28377:c2h17orf62
gene id: 28377:c2h17orf62
uniprot id: G1KT85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYBC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:LOC100555978
gene id: 28377:LOC100555978
uniprot id: G1KUS3
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:brpf1
gene id: 28377:brpf1
uniprot id: G1KJR0
names: Subcellular Location Annotation
messages: Nucleus

28377:chsy3
gene id: 28377:chsy3
uniprot id: G1K9G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

28377:erlec1
gene id: 28377:erlec1
uniprot id: G1KM94
names: Subcellular Location Annotation
messages: Endoplasmic reticulum lumen

28377:cers6
gene id: 28377:cers6
uniprot id: A0A803TT83
uniprot id: G1K9E6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

28377:churc1
gene id: 28377:churc1
uniprot id: G1KIE2
names: Similarity
messages: Belongs to the Churchill family.

28377:LOC100554401
gene id: 28377:LOC100554401
uniprot id: G1KKC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

28377:elovl4
gene id: 28377:elovl4
uniprot id: G1KTV6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL4 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Oligomer.
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

28377:ilf3
gene id: 28377:ilf3
uniprot id: G1KRG5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

28377:smc5
gene id: 28377:smc5
uniprot id: A0A803SYB1
uniprot id: G1K8W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Nucleus

28377:amotl2
gene id: 28377:amotl2
uniprot id: G1KJ49
names: Similarity
messages: Belongs to the angiomotin family.

28377:irf1
gene id: 28377:irf1
uniprot id: G1KMN6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

28377:csf1r
gene id: 28377:csf1r
uniprot id: G1KRD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Membrane

28377:nek9
gene id: 28377:nek9
uniprot id: G1KT87
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

28377:ube2l6
gene id: 28377:ube2l6
uniprot id: G1KG86
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

28377:LOC100566150
gene id: 28377:LOC100566150
uniprot id: A0A803TQY1
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

28377:ribc1
gene id: 28377:ribc1
uniprot id: G1KIU0
names: Similarity
messages: Belongs to the RIB43A family.

28377:uimc1
gene id: 28377:uimc1
uniprot id: G1KDZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAP80 family.
messages: Nucleus

28377:polr2d
gene id: 28377:polr2d
uniprot id: G1KDT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

28377:bnip1
gene id: 28377:bnip1
uniprot id: G1KQQ9
names: Subcellular Location Annotation
messages: Membrane

28377:dlc1
gene id: 28377:dlc1
uniprot id: A0A803T732
uniprot id: A0A803TK68
uniprot id: G1KI70
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.
messages: Interacts with EF1A1, facilitates EF1A1 distribution to the membrane periphery and ruffles upon growth factor stimulation and suppresses cell migration.
messages: Membrane
messages: focal adhesion

28377:samm50
gene id: 28377:samm50
uniprot id: G1KRW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

28377:dgkg
gene id: 28377:dgkg
uniprot id: A0A803TJA8
uniprot id: A0A803TU05
uniprot id: G1KHJ2
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

28377:lasp1
gene id: 28377:lasp1
uniprot id: A0A803T8G4
names: Function
names: Subcellular Location Annotation
messages: Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types.
messages: cell cortex
messages: cytoskeleton

28377:sufu
gene id: 28377:sufu
uniprot id: G1KCJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUFU family.
messages: Cytoplasm
messages: Nucleus

28377:tmem9
gene id: 28377:tmem9
uniprot id: A0A803TFB3
names: Similarity
messages: Belongs to the TMEM9 family.

28377:tgfb3
gene id: 28377:tgfb3
uniprot id: G1KTG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
messages: extracellular matrix

28377:ubqln1
gene id: 28377:ubqln1
uniprot id: G1KA21
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus
messages: autophagosome

28377:LOC100567378
gene id: 28377:LOC100567378
uniprot id: A0A803TPN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:isca1
gene id: 28377:isca1
uniprot id: A0A803TJK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

28377:nhs
gene id: 28377:nhs
uniprot id: G1KLB0
names: Similarity
messages: Belongs to the NHS family.

28377:hectd1
gene id: 28377:hectd1
uniprot id: G1KQQ3
names: Function
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

28377:spry2
gene id: 28377:spry2
uniprot id: G1KS17
names: Similarity
messages: Belongs to the sprouty family.

28377:xkr9
gene id: 28377:xkr9
uniprot id: G1KQA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

28377:amt
gene id: 28377:amt
uniprot id: G1KGM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

28377:nodal
gene id: 28377:nodal
uniprot id: G1KHQ1
names: Similarity
messages: Belongs to the TGF-beta family.

28377:kcnk9
gene id: 28377:kcnk9
uniprot id: G1K8B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane
messages: pH-dependent, voltage-insensitive, background potassium channel protein.

28377:LOC100561485
gene id: 28377:LOC100561485
uniprot id: A0A803TQU1
uniprot id: G1KTV4
names: Similarity
messages: Belongs to the paralemmin family.

28377:pcnp
gene id: 28377:pcnp
uniprot id: G1KLM9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus

28377:calcr
gene id: 28377:calcr
uniprot id: G1KNG6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Interacts with GPRASP2.
messages: Membrane

28377:c5ar1
gene id: 28377:c5ar1
uniprot id: H9G8H5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:nrxn3
gene id: 28377:nrxn3
uniprot id: G1KTT1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:ccdc43
gene id: 28377:ccdc43
uniprot id: G1KMG5
names: Similarity
messages: Belongs to the CCDC43 family.

28377:avl9
gene id: 28377:avl9
uniprot id: G1KIZ5
names: Subcellular Location Annotation
messages: Endosome
messages: Recycling endosome

28377:fdxr
gene id: 28377:fdxr
uniprot id: G1KEM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
messages: Mitochondrion
messages: Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.

28377:LOC100556624
gene id: 28377:LOC100556624
uniprot id: G1KMN7
names: Similarity
messages: Belongs to the cytochrome P450 family.

28377:tyr
gene id: 28377:tyr
uniprot id: G1KQJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

28377:uggt1
gene id: 28377:uggt1
uniprot id: G1KDP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

28377:orc6
gene id: 28377:orc6
uniprot id: H9GJX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

28377:cdc20
gene id: 28377:cdc20
uniprot id: G1KNN9
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

28377:edem2
gene id: 28377:edem2
uniprot id: G1KHS2
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

28377:eya2
gene id: 28377:eya2
uniprot id: G1KSX3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

28377:LOC100561045
gene id: 28377:LOC100561045
uniprot id: G1KKF9
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

28377:LOC100566106
gene id: 28377:LOC100566106
uniprot id: A0A803T1V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

28377:fam58a
gene id: 28377:fam58a
uniprot id: G1KIK6
names: Similarity
messages: Belongs to the cyclin family. Cyclin-like FAM58 subfamily.

28377:spty2d1
gene id: 28377:spty2d1
uniprot id: G1K891
names: Similarity
messages: Belongs to the SPT2 family.

28377:suv39h1
gene id: 28377:suv39h1
uniprot id: G1KF95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Nucleus
messages: centromere

28377:clul1
gene id: 28377:clul1
uniprot id: G1KHS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Secreted

28377:yipf1
gene id: 28377:yipf1
uniprot id: G1KIB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

28377:aasdh
gene id: 28377:aasdh
uniprot id: G1KIG6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

28377:vat1
gene id: 28377:vat1
uniprot id: G1KNV6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

28377:LOC100556950
gene id: 28377:LOC100556950
uniprot id: G1KM71
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:letmd1
gene id: 28377:letmd1
uniprot id: G1KV41
names: Subcellular Location Annotation
messages: Membrane

28377:LOC103277701
gene id: 28377:LOC103277701
uniprot id: A0A803TLA5
uniprot id: R4GDH8
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

28377:c3
gene id: 28377:c3
uniprot id: G1KQS3
uniprot id: G1KTS0
names: Subcellular Location Annotation
messages: Secreted

28377:LOC100553954
gene id: 28377:LOC100553954
uniprot id: G1KSN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

28377:gria2
gene id: 28377:gria2
uniprot id: A0A803SWT9
uniprot id: A0A803TZZ9
uniprot id: G1KT27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

28377:myh9
gene id: 28377:myh9
uniprot id: G1KSP5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

28377:foxp3
gene id: 28377:foxp3
uniprot id: G1KNU3
names: Subcellular Location Annotation
messages: Nucleus

28377:crem
gene id: 28377:crem
uniprot id: G1K907
names: Subcellular Location Annotation
messages: Nucleus

28377:acsl1
gene id: 28377:acsl1
uniprot id: G1KB02
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

28377:LOC100559058
gene id: 28377:LOC100559058
uniprot id: G1KYN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

28377:srd5a1
gene id: 28377:srd5a1
uniprot id: R4GBJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
messages: Membrane
messages: Microsome membrane

28377:tada3
gene id: 28377:tada3
uniprot id: G1KJG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

28377:galnt12
gene id: 28377:galnt12
uniprot id: G1KAJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

28377:rpe
gene id: 28377:rpe
uniprot id: G1KKI6
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

28377:ppp4r3b
gene id: 28377:ppp4r3b
uniprot id: G1KC48
names: Similarity
messages: Belongs to the SMEK family.

28377:eya1
gene id: 28377:eya1
uniprot id: A0A803SRT0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

28377:b3galt1
gene id: 28377:b3galt1
uniprot id: G1K9L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

28377:LOC100565748
gene id: 28377:LOC100565748
uniprot id: G1KK37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

28377:meox1
gene id: 28377:meox1
uniprot id: A0A803SPM2
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC100566752
gene id: 28377:LOC100566752
uniprot id: G1KUK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

28377:stt3b
gene id: 28377:stt3b
uniprot id: G1KPY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

28377:osbpl2
gene id: 28377:osbpl2
uniprot id: G1KD33
names: Similarity
messages: Belongs to the OSBP family.

28377:LOC100555467
gene id: 28377:LOC100555467
uniprot id: G1KNA5
names: Subcellular Location Annotation
messages: Membrane

28377:tm4sf4
gene id: 28377:tm4sf4
uniprot id: G1KGP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

28377:rdh10
gene id: 28377:rdh10
uniprot id: A0A803TJ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

28377:tle4
gene id: 28377:tle4
uniprot id: G1KBE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

28377:tmem183a
gene id: 28377:tmem183a
uniprot id: G1KDD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM183 family.
messages: Membrane

28377:inha
gene id: 28377:inha
uniprot id: A0A803T6Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.
messages: Secreted

28377:mcm5
gene id: 28377:mcm5
uniprot id: G1KSW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

28377:cmtm8
gene id: 28377:cmtm8
uniprot id: R4G9M5
names: Subcellular Location Annotation
messages: Membrane

28377:ccdc22
gene id: 28377:ccdc22
uniprot id: G1KNU1
names: Similarity
messages: Belongs to the CCDC22 family.

28377:dusp7
gene id: 28377:dusp7
uniprot id: G1KFU8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

28377:mstn
gene id: 28377:mstn
uniprot id: G1KCN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

28377:srprb
gene id: 28377:srprb
uniprot id: A0A803SSR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:LOC100560655
gene id: 28377:LOC100560655
uniprot id: A0A803TKE1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

28377:dock3
gene id: 28377:dock3
uniprot id: G1KGW0
names: Similarity
messages: Belongs to the DOCK family.

28377:znf277
gene id: 28377:znf277
uniprot id: G1KG84
names: Similarity
messages: Belongs to the ZNF277 family.

28377:gc
gene id: 28377:gc
uniprot id: G1KNL0
names: Function
names: Subcellular Location Annotation
messages: Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
messages: Secreted

28377:amigo1
gene id: 28377:amigo1
uniprot id: G1KKN6
names: Similarity
messages: Belongs to the immunoglobulin superfamily. AMIGO family.

28377:trappc13
gene id: 28377:trappc13
uniprot id: G1KRQ8
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

28377:suclg1
gene id: 28377:suclg1
uniprot id: G1K8H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.

28377:mmp20
gene id: 28377:mmp20
uniprot id: G1KUQ8
names: Similarity
messages: Belongs to the peptidase M10A family.

28377:gja1
gene id: 28377:gja1
uniprot id: G1KZB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

28377:ephx1
gene id: 28377:ephx1
uniprot id: G1KER3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

28377:grk2
gene id: 28377:grk2
uniprot id: G1KH29
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

28377:slc10a7
gene id: 28377:slc10a7
uniprot id: G1KCF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Cell membrane
messages: Does not show transport activity towards bile acids or steroid sulfates.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

28377:mri1
gene id: 28377:mri1
uniprot id: G1KBX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

28377:LOC100566411
gene id: 28377:LOC100566411
uniprot id: G1KFQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

28377:LOC100564185
gene id: 28377:LOC100564185
uniprot id: G1KT55
names: Similarity
messages: Belongs to the cytochrome P450 family.

28377:st8sia5
gene id: 28377:st8sia5
uniprot id: A0A803T542
uniprot id: A5I881
uniprot id: G1KME3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

28377:dnaja2
gene id: 28377:dnaja2
uniprot id: H9GK58
names: Subcellular Location Annotation
messages: Membrane

28377:ptprn
gene id: 28377:ptprn
uniprot id: G1KP25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

28377:gjc1
gene id: 28377:gjc1
uniprot id: G1KLV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Gamma-type subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

28377:vsnl1
gene id: 28377:vsnl1
uniprot id: G1K9T4
names: Function
messages: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

28377:celf1
gene id: 28377:celf1
uniprot id: G1KAD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

28377:fam208a
gene id: 28377:fam208a
uniprot id: A0A803SLZ1
uniprot id: A0A803SYN9
uniprot id: G1KER4
names: Similarity
messages: Belongs to the TASOR family.

28377:npepps
gene id: 28377:npepps
uniprot id: G1KGF3
names: Similarity
messages: Belongs to the peptidase M1 family.

28377:mtrf1l
gene id: 28377:mtrf1l
uniprot id: G1KED9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

28377:LOC100566235
gene id: 28377:LOC100566235
uniprot id: A0A803STI1
uniprot id: A0A803T5T5
uniprot id: A0A803TI18
uniprot id: G1KIQ1
names: Similarity
messages: Belongs to the SEC3 family.

28377:serping1
gene id: 28377:serping1
uniprot id: G1KG82
names: Similarity
messages: Belongs to the serpin family.

28377:bcl9
gene id: 28377:bcl9
uniprot id: G1KP94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

28377:fuca2
gene id: 28377:fuca2
uniprot id: G1KHC4
names: Function
names: Similarity
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.

28377:mpl
gene id: 28377:mpl
uniprot id: G1KYT2
names: Subcellular Location Annotation
messages: Membrane

28377:LOC100555135
gene id: 28377:LOC100555135
uniprot id: G1KNY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm
messages: May play a role in lipid transport protein in Schwann cells. May bind cholesterol.
messages: Monomer.

28377:plcg2
gene id: 28377:plcg2
uniprot id: A0A803SVM1
uniprot id: H9GF62
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

28377:dmrta1
gene id: 28377:dmrta1
uniprot id: G1KU29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

28377:acod1
gene id: 28377:acod1
uniprot id: A0A803SUN1
uniprot id: G1KWH4
names: Similarity
messages: Belongs to the PrpD family.

28377:nr1h2
gene id: 28377:nr1h2
uniprot id: G1KMJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

28377:ralyl
gene id: 28377:ralyl
uniprot id: R4G9A3
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

28377:keap1
gene id: 28377:keap1
uniprot id: G1KID3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KEAP1 family.
messages: Cytoplasm
messages: Nucleus

28377:LOC100564706
gene id: 28377:LOC100564706
uniprot id: G1KL94
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

28377:galnt11
gene id: 28377:galnt11
uniprot id: G1KPK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

28377:LOC100554815
gene id: 28377:LOC100554815
uniprot id: G1KTZ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:mief1
gene id: 28377:mief1
uniprot id: A0A803TFR7
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

28377:acy3
gene id: 28377:acy3
uniprot id: G1KHW7
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

28377:LOC100558396
gene id: 28377:LOC100558396
uniprot id: G1KVB5
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

28377:slc35a1
gene id: 28377:slc35a1
uniprot id: G1KQN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

28377:shq1
gene id: 28377:shq1
uniprot id: G1KQC4
names: Similarity
messages: Belongs to the SHQ1 family.

28377:snx3
gene id: 28377:snx3
uniprot id: G1KEW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome
messages: Endosome
messages: phagosome

28377:asrgl1
gene id: 28377:asrgl1
uniprot id: G1KHY8
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

28377:LOC103279306
gene id: 28377:LOC103279306
uniprot id: A0A803TFB1
names: Subcellular Location Annotation
messages: Secreted

28377:entpd3
gene id: 28377:entpd3
uniprot id: A0A803THC8
uniprot id: G1KBF4
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

28377:slc25a40
gene id: 28377:slc25a40
uniprot id: R4GA36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

28377:ptprn2
gene id: 28377:ptprn2
uniprot id: A0A803U0W4
names: Subcellular Location Annotation
messages: Membrane
messages: secretory vesicle membrane

28377:sept8
gene id: 28377:sept8
uniprot id: G1KN43
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

28377:tmcc2
gene id: 28377:tmcc2
uniprot id: A0A803TZB8
uniprot id: G1KPX0
names: Similarity
messages: Belongs to the TEX28 family.

28377:dync2h1
gene id: 28377:dync2h1
uniprot id: G1KM78
names: Similarity
messages: Belongs to the dynein heavy chain family.

28377:mtrf1
gene id: 28377:mtrf1
uniprot id: A0A803SWP5
uniprot id: G1K8Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

28377:fam212b
gene id: 28377:fam212b
uniprot id: A0A803TR73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

28377:cldn24
gene id: 28377:cldn24
uniprot id: G1KUS2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

28377:tshz1
gene id: 28377:tshz1
uniprot id: A0A803SYG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

28377:ca8
gene id: 28377:ca8
uniprot id: G1KEH4
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

28377:cd200
gene id: 28377:cd200
uniprot id: G1KQT7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28377:rps3a
gene id: 28377:rps3a
uniprot id: G1KBE1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S).
messages: Cytoplasm

28377:coq2
gene id: 28377:coq2
uniprot id: G1KKG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

28377:pi16
gene id: 28377:pi16
uniprot id: A0A803TV37
names: Similarity
messages: Belongs to the CRISP family.

28377:parl
gene id: 28377:parl
uniprot id: G1KD18
names: Subcellular Location Annotation
messages: Membrane

28377:mrps6
gene id: 28377:mrps6
uniprot id: A0A803TWF2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

28377:gnpat
gene id: 28377:gnpat
uniprot id: G1KAU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Peroxisome membrane

28377:nhej1
gene id: 28377:nhej1
uniprot id: G1KBL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XLF subfamily.
messages: Nucleus

28377:tm9sf2
gene id: 28377:tm9sf2
uniprot id: G1KIE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

28377:asah1
gene id: 28377:asah1
uniprot id: G1KFU3
names: Similarity
messages: Belongs to the acid ceramidase family.

28377:rnf13
gene id: 28377:rnf13
uniprot id: G1KGV9
names: Subcellular Location Annotation
messages: Membrane

28377:rnf182
gene id: 28377:rnf182
uniprot id: G1KC39
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with ATP6V0C.
messages: Membrane

28377:podxl2
gene id: 28377:podxl2
uniprot id: G1KGK8
names: Subcellular Location Annotation
messages: Membrane

28377:LOC100561960
gene id: 28377:LOC100561960
uniprot id: G1K868
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WASH1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Recycling endosome membrane

28377:xrcc1
gene id: 28377:xrcc1
uniprot id: H9G8R9
names: Subcellular Location Annotation
messages: Nucleus

28377:mast4
gene id: 28377:mast4
uniprot id: A0A803TNC4
uniprot id: A0A803TNR3
uniprot id: G1KSD0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

28377:ackr3
gene id: 28377:ackr3
uniprot id: G1KK52
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:calcb
gene id: 28377:calcb
uniprot id: A0A803U0U0
uniprot id: G1KMP3
names: Similarity
messages: Belongs to the calcitonin family.

28377:fgg
gene id: 28377:fgg
uniprot id: G1KRE0
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

28377:gprin3
gene id: 28377:gprin3
uniprot id: G1KWM0
names: Function
messages: May be involved in neurite outgrowth.

28377:picalm
gene id: 28377:picalm
uniprot id: A0A803T6K3
uniprot id: A0A803TMT4
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

28377:LOC100558251
gene id: 28377:LOC100558251
uniprot id: G1KKD4
names: Subcellular Location Annotation
messages: Membrane

28377:imp4
gene id: 28377:imp4
uniprot id: G1KET8
names: Subcellular Location Annotation
messages: nucleolus

28377:ptpn2
gene id: 28377:ptpn2
uniprot id: R4G923
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

28377:slc6a9
gene id: 28377:slc6a9
uniprot id: G1KQ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily.
messages: Cell membrane
messages: Membrane

28377:irf3
gene id: 28377:irf3
uniprot id: A0A0X7YTM9
uniprot id: G1KPE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

28377:hacl1
gene id: 28377:hacl1
uniprot id: G1KAP3
names: Similarity
messages: Belongs to the TPP enzyme family.

28377:rab32
gene id: 28377:rab32
uniprot id: A0A803U153
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

28377:serinc1
gene id: 28377:serinc1
uniprot id: G1K9H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

28377:hoxb5
gene id: 28377:hoxb5
uniprot id: A0A803TV01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

28377:ppt2
gene id: 28377:ppt2
uniprot id: G1KKE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the palmitoyl-protein thioesterase family.
messages: Lysosome

28377:mbtps1
gene id: 28377:mbtps1
uniprot id: G1KN46
names: Similarity
messages: Belongs to the peptidase S8 family.

28377:agk
gene id: 28377:agk
uniprot id: G1KL63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AGK family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

28377:atat1
gene id: 28377:atat1
uniprot id: G1KKM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase ATAT1 family.
messages: Cytoplasm
messages: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. May be involved in neuron development.
messages: axon
messages: clathrin-coated pit
messages: cytoskeleton
messages: focal adhesion
messages: spindle

28377:kcnc1
gene id: 28377:kcnc1
uniprot id: G1K883
names: Subcellular Location Annotation
messages: Membrane

28377:metrnl
gene id: 28377:metrnl
uniprot id: A0A803SM86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the meteorin family.
messages: Secreted

28377:gpbp1l1
gene id: 28377:gpbp1l1
uniprot id: G1KRH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

28377:p4hb
gene id: 28377:p4hb
uniprot id: G1KKB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

28377:gpcpd1
gene id: 28377:gpcpd1
uniprot id: A0A803SZ51
uniprot id: A0A803TWN4
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

28377:gabra1
gene id: 28377:gabra1
uniprot id: G1KQK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

28377:edem1
gene id: 28377:edem1
uniprot id: G1KMD7
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

28377:tmem50b
gene id: 28377:tmem50b
uniprot id: G1KCM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

28377:bckdha
gene id: 28377:bckdha
uniprot id: H9G813
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BCKDHA family.
messages: Heterotetramer of alpha and beta chains.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

28377:gucy1a2
gene id: 28377:gucy1a2
uniprot id: G1KKU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

28377:LOC100566604
gene id: 28377:LOC100566604
uniprot id: G1KLP5
names: Similarity
messages: Belongs to the ohanin/vespryn family.

28377:cnp
gene id: 28377:cnp
uniprot id: G1KTD6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2H phosphoesterase superfamily. CNPase family.
messages: Exists as monomers and homodimers.
messages: Melanosome
messages: Membrane

28377:LOC100565491
gene id: 28377:LOC100565491
uniprot id: G1KCL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

28377:mdk
gene id: 28377:mdk
uniprot id: A0A803T2L7
names: Similarity
messages: Belongs to the pleiotrophin family.

28377:stat3
gene id: 28377:stat3
uniprot id: G1KUK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

28377:rpap1
gene id: 28377:rpap1
uniprot id: G1KPH2
names: Similarity
messages: Belongs to the RPAP1 family.

28377:qrsl1
gene id: 28377:qrsl1
uniprot id: G1KEK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

28377:hn1
gene id: 28377:hn1
uniprot id: G1KF37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

28377:LOC100553620
gene id: 28377:LOC100553620
uniprot id: G1KGT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:anapc16
gene id: 28377:anapc16
uniprot id: G1K970
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

28377:LOC100565764
gene id: 28377:LOC100565764
uniprot id: G1K9M5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

28377:ppp1ca
gene id: 28377:ppp1ca
uniprot id: G1KHF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cytoplasm

28377:LOC100566872
gene id: 28377:LOC100566872
uniprot id: G1KRA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase CarF family.
messages: Membrane

28377:tma16
gene id: 28377:tma16
uniprot id: G1KDM4
names: Function
names: Similarity
names: Subunit
messages: Associates with pre-60S ribosomal particles.
messages: Belongs to the TMA16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.

28377:LOC100562073
gene id: 28377:LOC100562073
uniprot id: G1KDU9
names: Similarity
messages: Belongs to the PACS family.

28377:med21
gene id: 28377:med21
uniprot id: G1KM38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

28377:vsx1
gene id: 28377:vsx1
uniprot id: G1KP43
names: Subcellular Location Annotation
messages: Nucleus

28377:tcf7
gene id: 28377:tcf7
uniprot id: A0A803TZW1
uniprot id: G1KB47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

28377:psat1
gene id: 28377:psat1
uniprot id: G1KF15
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

28377:tbl1xr1
gene id: 28377:tbl1xr1
uniprot id: A0A803TZ34
uniprot id: G1KNU8
names: Similarity
messages: Belongs to the WD repeat EBI family.

28377:esrrb
gene id: 28377:esrrb
uniprot id: G1KTH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

28377:LOC100557568
gene id: 28377:LOC100557568
uniprot id: L7MZL7
uniprot id: R4GBG5
names: Similarity
messages: Belongs to the cytochrome P450 family.

28377:cdc25c
gene id: 28377:cdc25c
uniprot id: G1KG01
names: Similarity
messages: Belongs to the MPI phosphatase family.

28377:mtfr1
gene id: 28377:mtfr1
uniprot id: G1KT28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

28377:sfxn1
gene id: 28377:sfxn1
uniprot id: G1KQJ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

28377:ildr2
gene id: 28377:ildr2
uniprot id: A0A803SNM3
uniprot id: A0A803SPT2
uniprot id: A0A803TGJ6
uniprot id: G1KJ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

28377:mdh1
gene id: 28377:mdh1
uniprot id: G1KET7
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

28377:pomgnt1
gene id: 28377:pomgnt1
uniprot id: G1KAX0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose.
messages: The manganese ion interacts primarily with the substrate UDP-N-acetylglucosamine.
messages: The stem domain mediates specific interaction with beta-linked N-acetylglucosamine moieties of O-glycosylated proteins. It also interacts with its product, N-acetyl-beta-D-glucosaminyl-(1->2)-O-alpha-D-mannosylprotein.

28377:alg11
gene id: 28377:alg11
uniprot id: G1KT53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

28377:kiaa0196
gene id: 28377:kiaa0196
uniprot id: G1KJY7
names: Similarity
messages: Belongs to the strumpellin family.

28377:kcnk15
gene id: 28377:kcnk15
uniprot id: G1KWT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

28377:azin1
gene id: 28377:azin1
uniprot id: G1KIN5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

28377:gss
gene id: 28377:gss
uniprot id: G1KGM7
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

28377:bgn
gene id: 28377:bgn
uniprot id: G1KJA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: May be involved in collagen fiber assembly.
messages: extracellular matrix

28377:dynlrb2
gene id: 28377:dynlrb2
uniprot id: H9GEB0
names: Similarity
messages: Belongs to the GAMAD family.

28377:trpc4
gene id: 28377:trpc4
uniprot id: G1KU62
names: Subcellular Location Annotation
messages: Membrane

28377:grem1
gene id: 28377:grem1
uniprot id: G1KRN7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:spin1
gene id: 28377:spin1
uniprot id: A0A803TWI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

28377:jag1
gene id: 28377:jag1
uniprot id: G1K9X7
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

28377:mfsd1
gene id: 28377:mfsd1
uniprot id: G1KFY4
names: Subcellular Location Annotation
messages: Membrane

28377:hoxc11
gene id: 28377:hoxc11
uniprot id: G1KKK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

28377:st6galnac2
gene id: 28377:st6galnac2
uniprot id: G1KHS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

28377:unk
gene id: 28377:unk
uniprot id: G1KGG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

28377:riok2
gene id: 28377:riok2
uniprot id: G1KLM0
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

28377:pdgfc
gene id: 28377:pdgfc
uniprot id: G1KT70
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:zdhhc14
gene id: 28377:zdhhc14
uniprot id: G1KVC6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

28377:tex10
gene id: 28377:tex10
uniprot id: A0A803TD06
names: Similarity
messages: Belongs to the IPI1/TEX10 family.

28377:evpl
gene id: 28377:evpl
uniprot id: G1KYJ6
names: Subcellular Location Annotation
messages: cytoskeleton

28377:myc
gene id: 28377:myc
uniprot id: G1KK08
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus
messages: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.

28377:ugcg
gene id: 28377:ugcg
uniprot id: G1KTQ7
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

28377:pld5
gene id: 28377:pld5
uniprot id: G1KBT8
names: Similarity
messages: Belongs to the phospholipase D family.

28377:fundc1
gene id: 28377:fundc1
uniprot id: A0A803TNZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

28377:gpr61
gene id: 28377:gpr61
uniprot id: G1KKP0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:rtcb
gene id: 28377:rtcb
uniprot id: G1KQE8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Cytoplasm
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

28377:mfng
gene id: 28377:mfng
uniprot id: G1KRT9
names: Subcellular Location Annotation
messages: Membrane

28377:actr8
gene id: 28377:actr8
uniprot id: G1KLI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

28377:hlcs
gene id: 28377:hlcs
uniprot id: G1KI79
names: Similarity
messages: Belongs to the biotin--protein ligase family.

28377:tmem115
gene id: 28377:tmem115
uniprot id: G1KG08
names: Subcellular Location Annotation
messages: Membrane

28377:mcm9
gene id: 28377:mcm9
uniprot id: A0A803TKV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

28377:dnal4
gene id: 28377:dnal4
uniprot id: G1KH53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

28377:sptssb
gene id: 28377:sptssb
uniprot id: G1KUP1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:nus1
gene id: 28377:nus1
uniprot id: G1KPR7
names: Similarity
messages: Belongs to the UPP synthase family.

28377:dse
gene id: 28377:dse
uniprot id: G1KP68
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

28377:cd82
gene id: 28377:cd82
uniprot id: G1KPW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

28377:b3gnt8
gene id: 28377:b3gnt8
uniprot id: H9GQP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

28377:slc25a10
gene id: 28377:slc25a10
uniprot id: G1KKH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

28377:adam17
gene id: 28377:adam17
uniprot id: G1K9M0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

28377:ndc1
gene id: 28377:ndc1
uniprot id: G1KIA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

28377:sptbn1
gene id: 28377:sptbn1
uniprot id: A0A803TN83
uniprot id: G1KM40
names: Similarity
messages: Belongs to the spectrin family.

28377:gap43
gene id: 28377:gap43
uniprot id: G1KQH4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neuromodulin family.
messages: Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.
messages: Cell membrane
messages: Membrane
messages: Palmitoylated. Palmitoylation is essential for plasma membrane association.
messages: Synapse
messages: This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
messages: filopodium membrane
messages: growth cone membrane

28377:LOC100561221
gene id: 28377:LOC100561221
uniprot id: R4GDB1
names: Similarity
messages: Belongs to the peptidase S8 family.

28377:nln
gene id: 28377:nln
uniprot id: G1KRY5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

28377:mrps18b
gene id: 28377:mrps18b
uniprot id: A0A803SQW3
uniprot id: A0A803U087
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mS40 subfamily.
messages: Mitochondrion

28377:zc3h14
gene id: 28377:zc3h14
uniprot id: G1KNC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZC3H14 family.
messages: Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
messages: Nucleus speckle

28377:cd74
gene id: 28377:cd74
uniprot id: G1KQJ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:fam13b
gene id: 28377:fam13b
uniprot id: A0A803THG0
uniprot id: G1KYA6
names: Similarity
messages: Belongs to the FAM13 family.

28377:pelo
gene id: 28377:pelo
uniprot id: G1KCR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.
messages: Nucleus

28377:inpp5d
gene id: 28377:inpp5d
uniprot id: G1KF42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane

28377:dner
gene id: 28377:dner
uniprot id: G1KEJ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:fam163a
gene id: 28377:fam163a
uniprot id: A0A803TL05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

28377:ipo11
gene id: 28377:ipo11
uniprot id: A0A803TJL0
uniprot id: G1KHV5
names: Subcellular Location Annotation
messages: Cytoplasm

28377:dsel
gene id: 28377:dsel
uniprot id: G1KMA8
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

28377:s1pr3
gene id: 28377:s1pr3
uniprot id: G1KSQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

28377:nav3
gene id: 28377:nav3
uniprot id: G1KQ75
names: Similarity
messages: Belongs to the Nav/unc-53 family.

28377:clec11a
gene id: 28377:clec11a
uniprot id: G1KLV3
names: Subcellular Location Annotation
messages: Secreted

28377:LOC100566990
gene id: 28377:LOC100566990
uniprot id: A0A803T2J5
names: Similarity
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.

28377:LOC100561503
gene id: 28377:LOC100561503
uniprot id: A0A803TH23
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

28377:ndel1
gene id: 28377:ndel1
uniprot id: A0A803T1I2
uniprot id: A0A803TFN2
uniprot id: G1KU53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

28377:myo1d
gene id: 28377:myo1d
uniprot id: A0A803SLZ0
uniprot id: G1KSK0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

28377:lace1
gene id: 28377:lace1
uniprot id: G1KEW9
names: Similarity
messages: Belongs to the AFG1 ATPase family.

28377:pigm
gene id: 28377:pigm
uniprot id: G1KBW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

28377:cnnm1
gene id: 28377:cnnm1
uniprot id: G1KC03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

28377:kif16b
gene id: 28377:kif16b
uniprot id: G1K8J9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

28377:cacng2
gene id: 28377:cacng2
uniprot id: A0A803SKV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

28377:a4gnt
gene id: 28377:a4gnt
uniprot id: G1KIM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

28377:dlgap2
gene id: 28377:dlgap2
uniprot id: G1KDV0
names: Similarity
messages: Belongs to the SAPAP family.

28377:tm4sf18
gene id: 28377:tm4sf18
uniprot id: G1KGP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

28377:birc7
gene id: 28377:birc7
uniprot id: A0A803SWD0
names: Similarity
messages: Belongs to the IAP family.

28377:LOC100554659
gene id: 28377:LOC100554659
uniprot id: A0A803TSU9
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:camk2a
gene id: 28377:camk2a
uniprot id: A0A803TQZ5
uniprot id: L7MZY1
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

28377:rpl14
gene id: 28377:rpl14
uniprot id: G1KBH2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

28377:ugp2
gene id: 28377:ugp2
uniprot id: G1KEX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

28377:LOC100551988
gene id: 28377:LOC100551988
uniprot id: A0A803SXH3
names: Similarity
messages: Belongs to the peptidase S1 family. Snake venom subfamily.

28377:cmc1
gene id: 28377:cmc1
uniprot id: A0A803T2T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

28377:slc34a1
gene id: 28377:slc34a1
uniprot id: G1KFC5
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

28377:timp4
gene id: 28377:timp4
uniprot id: G1KNU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: Secreted

28377:LOC100563070
gene id: 28377:LOC100563070
uniprot id: G1KGE3
names: Similarity
messages: Belongs to the ohanin/vespryn family.

28377:apopt1
gene id: 28377:apopt1
uniprot id: A0A803TQD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COA8 family.
messages: Mitochondrion inner membrane

28377:acsl6
gene id: 28377:acsl6
uniprot id: G1KM83
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

28377:dlx6
gene id: 28377:dlx6
uniprot id: G1KQ69
names: Subcellular Location Annotation
messages: Nucleus

28377:banf2
gene id: 28377:banf2
uniprot id: R4G921
names: Subcellular Location Annotation
messages: Nucleus

28377:sema3c
gene id: 28377:sema3c
uniprot id: G1KRJ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:shcbp1
gene id: 28377:shcbp1
uniprot id: A0A803TRL7
uniprot id: H9GJQ9
names: Subcellular Location Annotation
messages: spindle

28377:fmnl1
gene id: 28377:fmnl1
uniprot id: A0A803SMZ0
uniprot id: G1KSN7
names: Similarity
messages: Belongs to the formin homology family.

28377:naa10
gene id: 28377:naa10
uniprot id: G1KM18
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

28377:ggps1
gene id: 28377:ggps1
uniprot id: G1K9G5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

28377:tns4
gene id: 28377:tns4
uniprot id: G1KS71
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

28377:mgat1
gene id: 28377:mgat1
uniprot id: G1KL90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

28377:bet1
gene id: 28377:bet1
uniprot id: G1KNI2
names: Subcellular Location Annotation
messages: Membrane

28377:med19
gene id: 28377:med19
uniprot id: G1KG31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

28377:wnt7b
gene id: 28377:wnt7b
uniprot id: G1KPV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

28377:glrx
gene id: 28377:glrx
uniprot id: G1KMZ3
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

28377:LOC100566300
gene id: 28377:LOC100566300
uniprot id: G1KRE4
names: Subcellular Location Annotation
messages: Membrane

28377:gfod1
gene id: 28377:gfod1
uniprot id: A0A803TH18
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

28377:LOC100555056
gene id: 28377:LOC100555056
uniprot id: A0A803T209
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

28377:pkp1
gene id: 28377:pkp1
uniprot id: R4GBL1
names: Similarity
messages: Belongs to the beta-catenin family.

28377:dennd6a
gene id: 28377:dennd6a
uniprot id: G1KBG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Endosome
messages: Recycling endosome

28377:armc8
gene id: 28377:armc8
uniprot id: G1KGB2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

28377:rps6ka2
gene id: 28377:rps6ka2
uniprot id: A0A803T4Z7
uniprot id: A0A803U1V0
uniprot id: G1KR88
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

28377:nrg1
gene id: 28377:nrg1
uniprot id: A0A803TMP5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:atg13
gene id: 28377:atg13
uniprot id: G1KCG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG13 family. Metazoan subfamily.
messages: Preautophagosomal structure

28377:ubr1
gene id: 28377:ubr1
uniprot id: G1KRV4
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

28377:capn9
gene id: 28377:capn9
uniprot id: G1KA77
names: Similarity
messages: Belongs to the peptidase C2 family.

28377:cenpn
gene id: 28377:cenpn
uniprot id: H9GEG8
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

28377:COX3
gene id: 28377:COX3
uniprot id: B3GSZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane

28377:aldh6a1
gene id: 28377:aldh6a1
uniprot id: G1KSG4
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

28377:gpr68
gene id: 28377:gpr68
uniprot id: G1KJC5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:ramp2
gene id: 28377:ramp2
uniprot id: G1KPU5
names: Similarity
messages: Belongs to the RAMP family.

28377:rxfp1
gene id: 28377:rxfp1
uniprot id: G1KST2
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:kcnk10
gene id: 28377:kcnk10
uniprot id: G1KNM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

28377:kiaa1324l
gene id: 28377:kiaa1324l
uniprot id: G1KSS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

28377:chrm3
gene id: 28377:chrm3
uniprot id: G1KC26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

28377:sdhaf4
gene id: 28377:sdhaf4
uniprot id: A0A803TG33
names: Similarity
messages: Belongs to the SDHAF4 family.

28377:lpcat2
gene id: 28377:lpcat2
uniprot id: H9GNF5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

28377:plg
gene id: 28377:plg
uniprot id: G1KBV2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Belongs to the peptidase S1 family. Snake venom subfamily.
messages: Converted into plasmin by plasminogen activators, both plasminogen and its activator being bound to fibrin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.
messages: Secreted

28377:capn7
gene id: 28377:capn7
uniprot id: G1KB21
names: Similarity
messages: Belongs to the peptidase C2 family.

28377:immt
gene id: 28377:immt
uniprot id: A0A803TAX1
uniprot id: G1KLN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

28377:LOC100567853
gene id: 28377:LOC100567853
uniprot id: G1KD64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

28377:mipep
gene id: 28377:mipep
uniprot id: A0A803TVD1
uniprot id: G1KBM1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

28377:LOC100552176
gene id: 28377:LOC100552176
uniprot id: G1KSZ1
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

28377:lyrm7
gene id: 28377:lyrm7
uniprot id: G1K9E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.
messages: Belongs to the complex I LYR family.
messages: Interacts with UQCRFS1.
messages: Mitochondrion matrix

28377:numbl
gene id: 28377:numbl
uniprot id: A0A803TG76
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a role in the process of neurogenesis.

28377:ldha
gene id: 28377:ldha
uniprot id: G1K888
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

28377:vps25
gene id: 28377:vps25
uniprot id: A0A803TFN7
names: Similarity
messages: Belongs to the VPS25 family.

28377:srsf2
gene id: 28377:srsf2
uniprot id: G1KHX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus

28377:LOC100563157
gene id: 28377:LOC100563157
uniprot id: L7MZV0
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

28377:foxp4
gene id: 28377:foxp4
uniprot id: A0A803STZ0
uniprot id: G1KAZ1
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC100566596
gene id: 28377:LOC100566596
uniprot id: A0A803TPU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

28377:slf2
gene id: 28377:slf2
uniprot id: A0A803THV6
uniprot id: A0A803U0A0
names: Similarity
messages: Belongs to the FAM178 family.

28377:tnr
gene id: 28377:tnr
uniprot id: G1KQK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

28377:ypel5
gene id: 28377:ypel5
uniprot id: A0A803SQ29
names: Similarity
messages: Belongs to the yippee family.

28377:plcd1
gene id: 28377:plcd1
uniprot id: A0A803T1M3
uniprot id: G1KDV8
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

28377:fabp2
gene id: 28377:fabp2
uniprot id: G1KNM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

28377:cav2
gene id: 28377:cav2
uniprot id: A0A803SS16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

28377:LOC100553362
gene id: 28377:LOC100553362
uniprot id: R4G9M8
names: Subcellular Location Annotation
messages: Membrane

28377:nxph3
gene id: 28377:nxph3
uniprot id: A0A803TKQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

28377:fat3
gene id: 28377:fat3
uniprot id: A0A803SS42
uniprot id: A0A803TH37
uniprot id: A0A803TVX6
uniprot id: G1KQA3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:elk1
gene id: 28377:elk1
uniprot id: G1KD37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

28377:inpp1
gene id: 28377:inpp1
uniprot id: G1KHB7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

28377:rsad1
gene id: 28377:rsad1
uniprot id: A0A803SSC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Mitochondrion

28377:lonp2
gene id: 28377:lonp2
uniprot id: H9GL04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
messages: Belongs to the peptidase S16 family.
messages: Peroxisome matrix

28377:LOC100554428
gene id: 28377:LOC100554428
uniprot id: G1KH64
names: Similarity
messages: Belongs to the FAM20 family.

28377:LOC100555183
gene id: 28377:LOC100555183
uniprot id: A0A803T7Z6
names: Similarity
messages: Belongs to the TMEM178 family.

28377:osbpl11
gene id: 28377:osbpl11
uniprot id: A0A803TJJ7
uniprot id: G1KJF7
names: Similarity
messages: Belongs to the OSBP family.

28377:LOC100553036
gene id: 28377:LOC100553036
uniprot id: G1KWS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:eif6
gene id: 28377:eif6
uniprot id: G1KE62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: nucleolus

28377:osgin1
gene id: 28377:osgin1
uniprot id: A0A803TC54
names: Similarity
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.

28377:LOC100554621
gene id: 28377:LOC100554621
uniprot id: G1KM91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

28377:nox4
gene id: 28377:nox4
uniprot id: A0A803T0F8
uniprot id: G1KQH3
names: Subcellular Location Annotation
messages: Membrane

28377:chst9
gene id: 28377:chst9
uniprot id: G1KAC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

28377:txnl4a
gene id: 28377:txnl4a
uniprot id: G1K996
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

28377:LOC100554103
gene id: 28377:LOC100554103
uniprot id: G1KLF4
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

28377:fgb
gene id: 28377:fgb
uniprot id: G1KRF4
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

28377:znf706
gene id: 28377:znf706
uniprot id: G1KI42
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

28377:nck2
gene id: 28377:nck2
uniprot id: G1KK46
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

28377:ihh
gene id: 28377:ihh
uniprot id: A0A803TAA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: Secreted
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

28377:elf2
gene id: 28377:elf2
uniprot id: A0A803T572
uniprot id: G1KA65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

28377:greb1l
gene id: 28377:greb1l
uniprot id: G1KH91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

28377:agt
gene id: 28377:agt
uniprot id: G1K9T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family.
messages: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
messages: Secreted
messages: Stimulates aldosterone release.

28377:LOC100564788
gene id: 28377:LOC100564788
uniprot id: G1KLZ7
names: Similarity
messages: Belongs to the aldo/keto reductase family.

28377:fgf14
gene id: 28377:fgf14
uniprot id: G1KBQ9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

28377:cnksr2
gene id: 28377:cnksr2
uniprot id: G1KYD6
names: Similarity
messages: Belongs to the CNKSR family.

28377:farsb
gene id: 28377:farsb
uniprot id: A0A803T1L6
uniprot id: G1KDC4
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

28377:apaf1
gene id: 28377:apaf1
uniprot id: G1KNE2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Monomer. Oligomerizes upon binding of cytochrome c and dATP.
messages: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.

28377:tarbp2
gene id: 28377:tarbp2
uniprot id: G1KZ83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TARBP2 family.
messages: Cytoplasm
messages: Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
messages: Self-associates. Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC.

28377:LOC100564195
gene id: 28377:LOC100564195
uniprot id: A0A803TR93
names: Similarity
messages: Belongs to the cornifelin family.

28377:chst1
gene id: 28377:chst1
uniprot id: G1KQ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

28377:tcta
gene id: 28377:tcta
uniprot id: A0A803U0H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTA family.
messages: Membrane

28377:phc3
gene id: 28377:phc3
uniprot id: A0A803T6U1
uniprot id: A0A803U0Q0
uniprot id: G1KRQ9
names: Subcellular Location Annotation
messages: Nucleus

28377:tprkb
gene id: 28377:tprkb
uniprot id: A0A803T344
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

28377:vip
gene id: 28377:vip
uniprot id: G1KEE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted
messages: VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.

28377:b4galnt2
gene id: 28377:b4galnt2
uniprot id: G1KF32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

28377:phactr1
gene id: 28377:phactr1
uniprot id: A0A803T8F1
uniprot id: G1KCS1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Nucleus
messages: Synapse

28377:hnrnpa1
gene id: 28377:hnrnpa1
uniprot id: A0A803TGK2
uniprot id: G1KG94
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

28377:LOC100567003
gene id: 28377:LOC100567003
uniprot id: G1KR32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.5/KCNA5 sub-subfamily.
messages: Cell membrane
messages: Membrane

28377:rbl1
gene id: 28377:rbl1
uniprot id: G1KFZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

28377:LOC100561640
gene id: 28377:LOC100561640
uniprot id: G1KMJ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28377:panx2
gene id: 28377:panx2
uniprot id: G1KAJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

28377:atg9a
gene id: 28377:atg9a
uniprot id: G1KNA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

28377:LOC100553635
gene id: 28377:LOC100553635
uniprot id: G1KVT7
names: Similarity
messages: Belongs to the peptidase M10A family.

28377:LOC100567856
gene id: 28377:LOC100567856
uniprot id: G1K953
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Monomer.

28377:LOC100566861
gene id: 28377:LOC100566861
uniprot id: G1KZA1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

28377:LOC100553421
gene id: 28377:LOC100553421
uniprot id: G1K9Q4
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

28377:dym
gene id: 28377:dym
uniprot id: A0A803TV22
uniprot id: G1KUM3
names: Similarity
messages: Belongs to the dymeclin family.

28377:atg4d
gene id: 28377:atg4d
uniprot id: G1KS12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

28377:tctn3
gene id: 28377:tctn3
uniprot id: G1KCU2
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

28377:nr1d1
gene id: 28377:nr1d1
uniprot id: G1KB93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

28377:cecr1
gene id: 28377:cecr1
uniprot id: G1KM25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

28377:tmem173
gene id: 28377:tmem173
uniprot id: G1KAA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STING family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: autophagosome membrane
messages: perinuclear region

28377:LOC103279484
gene id: 28377:LOC103279484
uniprot id: R4G9M9
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

28377:tspan4
gene id: 28377:tspan4
uniprot id: G1KR70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

28377:ism1
gene id: 28377:ism1
uniprot id: G1K920
names: Similarity
messages: Belongs to the isthmin family.

28377:LOC100558083
gene id: 28377:LOC100558083
uniprot id: G1KMX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

28377:tradd
gene id: 28377:tradd
uniprot id: G1KXS9
names: Subcellular Location Annotation
messages: Nucleus
messages: cytoskeleton

28377:syt2
gene id: 28377:syt2
uniprot id: G1KCC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

28377:acat2
gene id: 28377:acat2
uniprot id: G1KCU1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

28377:fgf1
gene id: 28377:fgf1
uniprot id: A0A803SLR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

28377:mpc2
gene id: 28377:mpc2
uniprot id: G1KIW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

28377:LOC100567523
gene id: 28377:LOC100567523
uniprot id: G1KB82
names: Similarity
messages: Belongs to the peptidase A1 family.

28377:eif2s2
gene id: 28377:eif2s2
uniprot id: A0A803TTC2
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

28377:nampt
gene id: 28377:nampt
uniprot id: A0A803TNL4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

28377:birc2
gene id: 28377:birc2
uniprot id: G1KMP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

28377:pp
gene id: 28377:pp
uniprot id: G1KLK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

28377:LOC100567056
gene id: 28377:LOC100567056
uniprot id: G1KW15
names: Similarity
names: Subunit
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
messages: Interacts with PDZK1.

28377:pfn2
gene id: 28377:pfn2
uniprot id: G1KGW8
names: Function
names: Similarity
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

28377:kbtbd8
gene id: 28377:kbtbd8
uniprot id: G1KQN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KBTBD8 family.
messages: Golgi apparatus
messages: spindle

28377:abcg1
gene id: 28377:abcg1
uniprot id: G1KBK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

28377:LOC100565902
gene id: 28377:LOC100565902
uniprot id: G1KH12
names: Similarity
messages: Belongs to the CRISP family.

28377:LOC100551610
gene id: 28377:LOC100551610
uniprot id: G1KLW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

28377:rc3h1
gene id: 28377:rc3h1
uniprot id: G1KQZ5
names: Subcellular Location Annotation
messages: P-body

28377:LOC100554742
gene id: 28377:LOC100554742
uniprot id: G1KP40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm
messages: May play a role in lipid transport protein in Schwann cells. May bind cholesterol.
messages: Monomer.

28377:btd
gene id: 28377:btd
uniprot id: G1KAS1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

28377:cpsf2
gene id: 28377:cpsf2
uniprot id: G1KIP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

28377:slc41a2
gene id: 28377:slc41a2
uniprot id: G1KRT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

28377:slc16a1
gene id: 28377:slc16a1
uniprot id: G1KUK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane
messages: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

28377:gys2
gene id: 28377:gys2
uniprot id: G1KTH7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

28377:wfikkn2
gene id: 28377:wfikkn2
uniprot id: G1K9Q5
names: Similarity
messages: Belongs to the WFIKKN family.

28377:LOC107982730
gene id: 28377:LOC107982730
uniprot id: R4G9I6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

28377:npm1
gene id: 28377:npm1
uniprot id: A0A803TXR4
uniprot id: G1KRE8
names: Similarity
messages: Belongs to the nucleoplasmin family.

28377:canx
gene id: 28377:canx
uniprot id: G1KSE2
names: Similarity
messages: Belongs to the calreticulin family.

28377:LOC100558455
gene id: 28377:LOC100558455
uniprot id: G1KT34
names: Cofactor
messages: Binds 1 zinc ion per subunit.

28377:ndfip2
gene id: 28377:ndfip2
uniprot id: A0A803TLR5
names: Subcellular Location Annotation
messages: Membrane

28377:aim1
gene id: 28377:aim1
uniprot id: G1KEG6
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

28377:cpb2
gene id: 28377:cpb2
uniprot id: G1KSK1
names: Similarity
messages: Belongs to the peptidase M14 family.

28377:rpl23
gene id: 28377:rpl23
uniprot id: A0A803SPV1
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

28377:cnot10
gene id: 28377:cnot10
uniprot id: G1KQD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT10 family.
messages: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.
messages: Cytoplasm
messages: Nucleus

28377:grin2c
gene id: 28377:grin2c
uniprot id: G1KEI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

28377:cntn1
gene id: 28377:cntn1
uniprot id: G1KSH9
names: Similarity
messages: Belongs to the immunoglobulin superfamily. Contactin family.

28377:vdac1
gene id: 28377:vdac1
uniprot id: G1KB85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft

28377:pcyt1b
gene id: 28377:pcyt1b
uniprot id: A0A803TAZ9
uniprot id: G1KG28
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

28377:stk10
gene id: 28377:stk10
uniprot id: G1KR20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Cell membrane

28377:pno1
gene id: 28377:pno1
uniprot id: G1K9A2
names: Similarity
messages: Belongs to the PNO1 family.

28377:mon1a
gene id: 28377:mon1a
uniprot id: G1KHU2
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

28377:rpl7l1
gene id: 28377:rpl7l1
uniprot id: A0A803TL42
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

28377:arl6ip4
gene id: 28377:arl6ip4
uniprot id: A0A803TQ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL6IP4 family.
messages: Nucleus speckle
messages: nucleolus

28377:atf7
gene id: 28377:atf7
uniprot id: G1K969
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Homodimer; binds DNA as homodimer. Heterodimer; heterodimerizes with other members of ATF family and with JUN family members.
messages: Nucleus
messages: Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation. In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes such as STAT1 in adipocytes, or genes involved in innate immunity in macrophages and adipocytes. Stress induces ATF7 phosphorylation that disrupts interactions with histone methyltransferase and enhances the association with coactivators containing histone acetyltransferase and/or histone demethylase, leading to disruption of the heterochromatin-like structure and subsequently transcriptional activation. In response to TNF-alpha, which is induced by various stresses, phosphorylated ATF7 and telomerase are released from telomeres leading to telomere shortening.

28377:xdh
gene id: 28377:xdh
uniprot id: G1KG49
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Peroxisome

28377:mtap
gene id: 28377:mtap
uniprot id: G1KU49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

28377:rpl26l1
gene id: 28377:rpl26l1
uniprot id: G1KQT1
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

28377:tssc4
gene id: 28377:tssc4
uniprot id: G1KB35
names: Similarity
messages: Belongs to the TSSC4 family.

28377:mnf1
gene id: 28377:mnf1
uniprot id: A0A803T101
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

28377:acy1
gene id: 28377:acy1
uniprot id: G1KLT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Cytoplasm

28377:frg1
gene id: 28377:frg1
uniprot id: G1KFW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: Cajal body
messages: nucleolus

28377:cdh5
gene id: 28377:cdh5
uniprot id: H9G471
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell junction
messages: Cell membrane
messages: Membrane

28377:LOC103278044
gene id: 28377:LOC103278044
uniprot id: A0A803TFD0
names: Similarity
messages: Belongs to the ohanin/vespryn family.

28377:grm4
gene id: 28377:grm4
uniprot id: G1KS01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

28377:slc41a3
gene id: 28377:slc41a3
uniprot id: A0A803SSQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

28377:mettl14
gene id: 28377:mettl14
uniprot id: G1KP31
names: Similarity
messages: Belongs to the MT-A70-like family.

28377:ubr2
gene id: 28377:ubr2
uniprot id: G1K908
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

28377:asph
gene id: 28377:asph
uniprot id: A0A803SZY2
names: Subcellular Location Annotation
messages: Membrane

28377:pik3cg
gene id: 28377:pik3cg
uniprot id: G1KQF3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

28377:glyctk
gene id: 28377:glyctk
uniprot id: G1KFJ3
names: Similarity
messages: Belongs to the glycerate kinase type-2 family.

28377:vgll2
gene id: 28377:vgll2
uniprot id: G1KPN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

28377:tagln3
gene id: 28377:tagln3
uniprot id: G1KQR0
names: Similarity
messages: Belongs to the calponin family.

28377:LOC100564326
gene id: 28377:LOC100564326
uniprot id: G1KFK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

28377:vrtn
gene id: 28377:vrtn
uniprot id: G1KSL7
names: Similarity
messages: Belongs to the vertnin family.

28377:taf13
gene id: 28377:taf13
uniprot id: G1KJT3
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC100562477
gene id: 28377:LOC100562477
uniprot id: G1KNG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

28377:obfc1
gene id: 28377:obfc1
uniprot id: G1KDE1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
messages: Component of the CST complex.
messages: Nucleus
messages: telomere

28377:rab18
gene id: 28377:rab18
uniprot id: A0A803TH47
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

28377:fam162b
gene id: 28377:fam162b
uniprot id: A0A803STD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

28377:kcne4
gene id: 28377:kcne4
uniprot id: A0A803TES1
names: Similarity
messages: Belongs to the potassium channel KCNE family.

28377:LOC100558735
gene id: 28377:LOC100558735
uniprot id: G1KAZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

28377:gatb
gene id: 28377:gatb
uniprot id: G1KB84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

28377:dcaf13
gene id: 28377:dcaf13
uniprot id: G1KIY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

28377:wnt2b
gene id: 28377:wnt2b
uniprot id: G1KUI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

28377:htra1
gene id: 28377:htra1
uniprot id: A0A803T192
names: Similarity
messages: Belongs to the peptidase S1C family.

28377:irf7
gene id: 28377:irf7
uniprot id: G1KQL4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

28377:fam3d
gene id: 28377:fam3d
uniprot id: G1KL39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

28377:LOC100557105
gene id: 28377:LOC100557105
uniprot id: A0A803T006
names: Similarity
messages: Belongs to the dickkopf family.

28377:klhl3
gene id: 28377:klhl3
uniprot id: G1KTL8
names: Subcellular Location Annotation
messages: cytoskeleton
messages: cytosol

28377:dip2c
gene id: 28377:dip2c
uniprot id: A0A803SM24
uniprot id: A0A803TDP6
uniprot id: G1KB76
names: Similarity
messages: Belongs to the DIP2 family.

28377:cog6
gene id: 28377:cog6
uniprot id: G1KSU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COG6 family.
messages: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
messages: Golgi apparatus membrane
messages: Membrane
messages: Required for normal Golgi function.

28377:arl6ip5
gene id: 28377:arl6ip5
uniprot id: A0A803TEF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

28377:kif18b
gene id: 28377:kif18b
uniprot id: G1KGP3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

28377:gldc
gene id: 28377:gldc
uniprot id: G1KCW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

28377:mx1
gene id: 28377:mx1
uniprot id: G1KEM8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

28377:chaf1b
gene id: 28377:chaf1b
uniprot id: G1KMQ3
names: Subcellular Location Annotation
messages: Nucleus

28377:pard6g
gene id: 28377:pard6g
uniprot id: G1K9E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

28377:ranbp9
gene id: 28377:ranbp9
uniprot id: G1KC27
names: Similarity
messages: Belongs to the RANBP9/10 family.

28377:mpc1
gene id: 28377:mpc1
uniprot id: G1KR89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

28377:b4galt7
gene id: 28377:b4galt7
uniprot id: G1KFJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

28377:ap4s1
gene id: 28377:ap4s1
uniprot id: G1KQN3
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

28377:tfcp2l1
gene id: 28377:tfcp2l1
uniprot id: G1KCS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

28377:LOC100557289
gene id: 28377:LOC100557289
uniprot id: A0A803SVQ5
uniprot id: A0A803THF8
names: Similarity
messages: Belongs to the CD99 family.

28377:foxd3
gene id: 28377:foxd3
uniprot id: G1KHB1
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC100553238
gene id: 28377:LOC100553238
uniprot id: G1KXX7
names: Similarity
messages: Belongs to the peptidase M10A family.

28377:mfsd6l
gene id: 28377:mfsd6l
uniprot id: A0A803TKR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

28377:mrgbp
gene id: 28377:mrgbp
uniprot id: R4GAN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Nucleus

28377:mlh3
gene id: 28377:mlh3
uniprot id: A0A803T4A0
uniprot id: G1KT63
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

28377:psma6
gene id: 28377:psma6
uniprot id: G1K9Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus

28377:slc35b2
gene id: 28377:slc35b2
uniprot id: G1KQ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

28377:LOC100562140
gene id: 28377:LOC100562140
uniprot id: G1KKY5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

28377:unc5c
gene id: 28377:unc5c
uniprot id: G1KPC0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

28377:dtx4
gene id: 28377:dtx4
uniprot id: G1KFR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

28377:LOC100562810
gene id: 28377:LOC100562810
uniprot id: G1KAS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

28377:mpp6
gene id: 28377:mpp6
uniprot id: A0A803TEN1
uniprot id: G1KNN4
names: Similarity
messages: Belongs to the MAGUK family.

28377:ndufaf3
gene id: 28377:ndufaf3
uniprot id: G1KMA7
names: Function
names: Subcellular Location Annotation
messages: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Membrane
messages: Mitochondrion inner membrane
messages: Nucleus

28377:map1lc3c
gene id: 28377:map1lc3c
uniprot id: A0A803TLH6
names: Similarity
messages: Belongs to the ATG8 family.

28377:klkb1
gene id: 28377:klkb1
uniprot id: G1K9G8
names: Similarity
messages: Belongs to the peptidase S1 family. Snake venom subfamily.

28377:xrcc6
gene id: 28377:xrcc6
uniprot id: G1KCX9
names: Subcellular Location Annotation
messages: Nucleus

28377:atp2c1
gene id: 28377:atp2c1
uniprot id: G1KAI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Golgi stack membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer. Homodimer.
messages: trans-Golgi network membrane

28377:LOC100553977
gene id: 28377:LOC100553977
uniprot id: H9G8Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNF-like-inhibitor family.
messages: Secreted

28377:rapgef6
gene id: 28377:rapgef6
uniprot id: A0A803T248
uniprot id: A0A803TMM0
uniprot id: G1KLW8
names: Similarity
messages: Belongs to the RAPGEF2 family.

28377:COX2
gene id: 28377:COX2
uniprot id: B3GSZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

28377:pnldc1
gene id: 28377:pnldc1
uniprot id: G1KP33
names: Similarity
messages: Belongs to the CAF1 family.

28377:eny2
gene id: 28377:eny2
uniprot id: A0A803T5D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

28377:prkag1
gene id: 28377:prkag1
uniprot id: G1KHH2
names: Similarity
names: Subunit
messages: AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or PRKAG3). Interacts with FNIP1 and FNIP2.
messages: Belongs to the 5'-AMP-activated protein kinase gamma subunit family.

28377:dtymk
gene id: 28377:dtymk
uniprot id: G1K8P8
names: Similarity
messages: Belongs to the thymidylate kinase family.

28377:lnpep
gene id: 28377:lnpep
uniprot id: G1KM27
names: Similarity
messages: Belongs to the peptidase M1 family.

28377:rps16
gene id: 28377:rps16
uniprot id: G1KPL2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

28377:kdm3b
gene id: 28377:kdm3b
uniprot id: G1KG85
names: Subcellular Location Annotation
messages: Nucleus

28377:dlx3
gene id: 28377:dlx3
uniprot id: A0A803TF43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

28377:alas2
gene id: 28377:alas2
uniprot id: A0A803T105
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

28377:LOC100556842
gene id: 28377:LOC100556842
uniprot id: H9G9C0
names: Similarity
messages: Belongs to the cytochrome P450 family.

28377:fam83d
gene id: 28377:fam83d
uniprot id: A0A803SS20
names: Similarity
messages: Belongs to the FAM83 family.

28377:spryd4
gene id: 28377:spryd4
uniprot id: G1KYE7
names: Similarity
messages: Belongs to the ohanin/vespryn family.

28377:kif3a
gene id: 28377:kif3a
uniprot id: A0A803T2I2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

28377:LOC100565481
gene id: 28377:LOC100565481
uniprot id: M1ZMM8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

28377:LOC100555193
gene id: 28377:LOC100555193
uniprot id: A0A803T988
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

28377:LOC100555911
gene id: 28377:LOC100555911
uniprot id: G1KF88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:gpr137b
gene id: 28377:gpr137b
uniprot id: G1KAK8
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

28377:LOC100567848
gene id: 28377:LOC100567848
uniprot id: G1KAW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

28377:lrp4
gene id: 28377:lrp4
uniprot id: G1KC02
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:nr3c1
gene id: 28377:nr3c1
uniprot id: G1KP59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

28377:arl14
gene id: 28377:arl14
uniprot id: G1KGE8
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

28377:LOC100564498
gene id: 28377:LOC100564498
uniprot id: G1KM80
names: Similarity
messages: Belongs to the CRISP family.

28377:cbfb
gene id: 28377:cbfb
uniprot id: G1KNE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF-beta family.
messages: Nucleus

28377:efhc2
gene id: 28377:efhc2
uniprot id: G1KUH5
names: Subcellular Location Annotation
messages: cilium axoneme

28377:uchl1
gene id: 28377:uchl1
uniprot id: G1KLS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C12 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:LOC100565099
gene id: 28377:LOC100565099
uniprot id: G1KL27
names: Similarity
messages: Belongs to the ohanin/vespryn family.

28377:nemp2
gene id: 28377:nemp2
uniprot id: G1K8U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

28377:pitpnm1
gene id: 28377:pitpnm1
uniprot id: G1KJQ7
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

28377:plk4
gene id: 28377:plk4
uniprot id: G1KLA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
messages: centriole

28377:polr3h
gene id: 28377:polr3h
uniprot id: G1KL02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

28377:mfsd5
gene id: 28377:mfsd5
uniprot id: G1KFP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Cell membrane
messages: Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
messages: Membrane

28377:kitlg
gene id: 28377:kitlg
uniprot id: R4GD07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCF family.
messages: Cytoplasm
messages: Homodimer, non-covalently linked.
messages: Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis.
messages: Secreted
messages: filopodium
messages: lamellipodium

28377:scml4
gene id: 28377:scml4
uniprot id: G1KEN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

28377:grm2
gene id: 28377:grm2
uniprot id: G1KL62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

28377:LOC100559198
gene id: 28377:LOC100559198
uniprot id: G1KBJ5
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

28377:LOC100566102
gene id: 28377:LOC100566102
uniprot id: G1KMI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

28377:edil3
gene id: 28377:edil3
uniprot id: G1KL84
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:ano6
gene id: 28377:ano6
uniprot id: A0A803T2F6
uniprot id: G1KAT6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:fam98b
gene id: 28377:fam98b
uniprot id: G1KRU8
names: Similarity
messages: Belongs to the FAM98 family.

28377:LOC100554488
gene id: 28377:LOC100554488
uniprot id: G1KLP8
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

28377:ppp2r2d
gene id: 28377:ppp2r2d
uniprot id: G1KHE3
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

28377:hsdl1
gene id: 28377:hsdl1
uniprot id: A0A803SVI5
uniprot id: G1KN59
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28377:LOC100565295
gene id: 28377:LOC100565295
uniprot id: G1KLA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Belongs to the ohanin/vespryn family.
messages: Membrane

28377:clrn2
gene id: 28377:clrn2
uniprot id: G1KKZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

28377:hcrt
gene id: 28377:hcrt
uniprot id: G1KUK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the orexin family.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum
messages: Synapse
messages: Vesicle

28377:csnk1d
gene id: 28377:csnk1d
uniprot id: A0A803TIN8
uniprot id: A0A803TR49
uniprot id: G1KAV5
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:cc2d1b
gene id: 28377:cc2d1b
uniprot id: G1KHH0
names: Similarity
messages: Belongs to the CC2D1 family.

28377:zdhhc5
gene id: 28377:zdhhc5
uniprot id: G1KG66
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

28377:cryl1
gene id: 28377:cryl1
uniprot id: G1KAH7
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

28377:poc5
gene id: 28377:poc5
uniprot id: G1KHQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POC5 family.
messages: Essential for the assembly of the distal half of centrioles, required for centriole elongation.
messages: centriole

28377:pcid2
gene id: 28377:pcid2
uniprot id: G1K8D9
names: Similarity
messages: Belongs to the CSN12 family.

28377:stx6
gene id: 28377:stx6
uniprot id: G1KD93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Golgi apparatus membrane

28377:tmem177
gene id: 28377:tmem177
uniprot id: G1KCB2
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

28377:arglu1
gene id: 28377:arglu1
uniprot id: G1KAX2
names: Similarity
messages: Belongs to the UPF0430 family.

28377:sost
gene id: 28377:sost
uniprot id: A0A803TJI0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the sclerostin family.
messages: Interacts with LRP4 (via the extracellular domain); the interaction facilitates the inhibition of Wnt signaling. Interacts with LRP5 (via the first two YWTD-EGF repeat domains); the interaction inhibits Wnt-mediated signaling. Interacts with LRP6.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

28377:aspn
gene id: 28377:aspn
uniprot id: G1KII0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: extracellular matrix

28377:LOC100561418
gene id: 28377:LOC100561418
uniprot id: G1K8Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

28377:hoxb7
gene id: 28377:hoxb7
uniprot id: A0A803TRP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

28377:bicd1
gene id: 28377:bicd1
uniprot id: G1KMR4
names: Similarity
messages: Belongs to the BicD family.

28377:c2h5orf63
gene id: 28377:c2h5orf63
uniprot id: A0A803U1W1
names: Similarity
messages: Belongs to the glutaredoxin family.

28377:LOC100566597
gene id: 28377:LOC100566597
uniprot id: G1KCJ4
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:LOC100553899
gene id: 28377:LOC100553899
uniprot id: G1KUB8
names: Subcellular Location Annotation
messages: Membrane

28377:nsun3
gene id: 28377:nsun3
uniprot id: G1K8I3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

28377:rassf1
gene id: 28377:rassf1
uniprot id: A0A803TAD7
names: Subcellular Location Annotation
messages: cytoskeleton

28377:gpr179
gene id: 28377:gpr179
uniprot id: A0A803SMV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

28377:klhl15
gene id: 28377:klhl15
uniprot id: G1KGI5
names: Subcellular Location Annotation
messages: Nucleus

28377:ero1b
gene id: 28377:ero1b
uniprot id: G1KAL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

28377:LOC103278063
gene id: 28377:LOC103278063
uniprot id: A0A803TLI2
names: Similarity
messages: Belongs to the ohanin/vespryn family.

28377:atp23
gene id: 28377:atp23
uniprot id: G1K9M9
names: Similarity
messages: Belongs to the peptidase M76 family.

28377:rps5
gene id: 28377:rps5
uniprot id: A0A803TUU8
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

28377:agpat1
gene id: 28377:agpat1
uniprot id: A0A803TN66
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

28377:cfl2
gene id: 28377:cfl2
uniprot id: G1KAM4
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

28377:ccdc39
gene id: 28377:ccdc39
uniprot id: G1KCH7
names: Similarity
messages: Belongs to the CCDC39 family.

28377:polr3f
gene id: 28377:polr3f
uniprot id: G1KPS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

28377:pde7a
gene id: 28377:pde7a
uniprot id: R4GB46
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

28377:c2h19orf53
gene id: 28377:c2h19orf53
uniprot id: G1KIL8
names: Similarity
messages: Belongs to the UPF0390 family.

28377:b3gnt2
gene id: 28377:b3gnt2
uniprot id: G1KEJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

28377:slc4a9
gene id: 28377:slc4a9
uniprot id: G1KNW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

28377:scg2
gene id: 28377:scg2
uniprot id: G1KCZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

28377:LOC100555583
gene id: 28377:LOC100555583
uniprot id: G1KN79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Cell membrane
messages: Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.
messages: Membrane

28377:kif23
gene id: 28377:kif23
uniprot id: A0A803SKR8
uniprot id: A0A803TXD2
uniprot id: G1KA35
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

28377:khdrbs2
gene id: 28377:khdrbs2
uniprot id: G1KFP6
names: Similarity
messages: Belongs to the KHDRBS family.

28377:isy1
gene id: 28377:isy1
uniprot id: G1KNC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

28377:LOC100566849
gene id: 28377:LOC100566849
uniprot id: R4GCD6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

28377:smim19
gene id: 28377:smim19
uniprot id: G1KIM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM19 family.
messages: Membrane

28377:ric8a
gene id: 28377:ric8a
uniprot id: G1KU21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

28377:fam105a
gene id: 28377:fam105a
uniprot id: G1KEE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

28377:fam189a2
gene id: 28377:fam189a2
uniprot id: G1K974
names: Similarity
messages: Belongs to the ENTREP family.

28377:ccdc53
gene id: 28377:ccdc53
uniprot id: A0A803TE02
names: Similarity
messages: Belongs to the CCDC53 family.

28377:mon1b
gene id: 28377:mon1b
uniprot id: G1KEY9
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

28377:pgm3
gene id: 28377:pgm3
uniprot id: G1KTQ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

28377:epb41l5
gene id: 28377:epb41l5
uniprot id: A0A803T4K6
uniprot id: G1KCG3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Photoreceptor inner segment
messages: Plays a role in the formation and organization of tight junctions during the establishment of polarity in epithelial cells.

28377:rrp15
gene id: 28377:rrp15
uniprot id: G1KQF4
names: Similarity
messages: Belongs to the RRP15 family.

28377:sh3gl2
gene id: 28377:sh3gl2
uniprot id: A0A803T859
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

28377:cask
gene id: 28377:cask
uniprot id: A0A803T0M4
uniprot id: A0A803U1J1
uniprot id: G1KUI6
names: Similarity
messages: Belongs to the MAGUK family.

28377:prps2
gene id: 28377:prps2
uniprot id: G1K9N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

28377:lbh
gene id: 28377:lbh
uniprot id: A0A803TZ49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LBH family.
messages: Cytoplasm
messages: Nucleus
messages: Transcriptional activator.

28377:ormdl3
gene id: 28377:ormdl3
uniprot id: G1KBQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

28377:sema4g
gene id: 28377:sema4g
uniprot id: G1KCD5
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:scarb2
gene id: 28377:scarb2
uniprot id: G1KMI7
names: Similarity
messages: Belongs to the CD36 family.

28377:LOC100554861
gene id: 28377:LOC100554861
uniprot id: G1KFS6
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Monomer.

28377:elovl5
gene id: 28377:elovl5
uniprot id: G1KHX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL5 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: dendrite

28377:c3hxorf23
gene id: 28377:c3hxorf23
uniprot id: G1KMH8
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

28377:slc30a9
gene id: 28377:slc30a9
uniprot id: G1KLV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum
messages: Membrane
messages: Nucleus
messages: Vesicle

28377:ampd2
gene id: 28377:ampd2
uniprot id: A0A803SSN3
uniprot id: A0A803SYK8
uniprot id: A0A803THQ2
uniprot id: G1KLF1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

28377:phospho1
gene id: 28377:phospho1
uniprot id: G1KEZ8
uniprot id: R4GAZ4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

28377:ndufaf2
gene id: 28377:ndufaf2
uniprot id: A0A803TDD4
names: Similarity
messages: Belongs to the complex I NDUFA12 subunit family.

28377:ddx11
gene id: 28377:ddx11
uniprot id: G1K869
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

28377:col4a3
gene id: 28377:col4a3
uniprot id: G1KCR9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

28377:mnd1
gene id: 28377:mnd1
uniprot id: A0A803T3K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MND1 family.
messages: Nucleus
messages: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.

28377:slc37a1
gene id: 28377:slc37a1
uniprot id: G1KBB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

28377:gpr6
gene id: 28377:gpr6
uniprot id: G1KXE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:rpl22l1
gene id: 28377:rpl22l1
uniprot id: G1KS27
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

28377:cpne4
gene id: 28377:cpne4
uniprot id: G1K9L1
names: Similarity
messages: Belongs to the copine family.

28377:plpp1
gene id: 28377:plpp1
uniprot id: A0A803SRP0
uniprot id: A0A803TNL0
uniprot id: G1KQN7
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: caveola

28377:tamm41
gene id: 28377:tamm41
uniprot id: R4G9U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Mitochondrion inner membrane

28377:pi4k2a
gene id: 28377:pi4k2a
uniprot id: G1KBF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

28377:mrps27
gene id: 28377:mrps27
uniprot id: G1KJD7
names: Subcellular Location Annotation
messages: Mitochondrion

28377:kif19
gene id: 28377:kif19
uniprot id: G1KQL0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

28377:c1h14orf1
gene id: 28377:c1h14orf1
uniprot id: A0A803TRX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:dcbld2
gene id: 28377:dcbld2
uniprot id: G1KKS5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:LOC100555068
gene id: 28377:LOC100555068
uniprot id: G1KN80
names: Similarity
messages: Belongs to the peptidase A1 family.

28377:lrrc8e
gene id: 28377:lrrc8e
uniprot id: G1KJG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

28377:clcf1
gene id: 28377:clcf1
uniprot id: A0A803T531
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

28377:b3gnt9
gene id: 28377:b3gnt9
uniprot id: G1KN94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

28377:taf5l
gene id: 28377:taf5l
uniprot id: G1K983
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

28377:nelfe
gene id: 28377:nelfe
uniprot id: G1KLE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NELF-E family.
messages: Chromosome
messages: Nucleus

28377:kat2a
gene id: 28377:kat2a
uniprot id: G1KUL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus
messages: centrosome

28377:usp44
gene id: 28377:usp44
uniprot id: G1KPI7
names: Similarity
messages: Belongs to the peptidase C19 family.

28377:plin2
gene id: 28377:plin2
uniprot id: A0A803SXS3
names: Similarity
messages: Belongs to the perilipin family.

28377:mab21l2
gene id: 28377:mab21l2
uniprot id: A0A803T3X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mab-21 family.
messages: Cytoplasm
messages: Nucleus

28377:LOC100564832
gene id: 28377:LOC100564832
uniprot id: G1KPB0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

28377:sypl2
gene id: 28377:sypl2
uniprot id: G1KKM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

28377:syt14
gene id: 28377:syt14
uniprot id: A0A803TIR7
uniprot id: G1K9E7
names: Similarity
messages: Belongs to the synaptotagmin family.

28377:actr3b
gene id: 28377:actr3b
uniprot id: G1KKF5
names: Similarity
messages: Belongs to the actin family.

28377:grb2
gene id: 28377:grb2
uniprot id: G1KFH8
names: Subcellular Location Annotation
messages: Endosome
messages: Golgi apparatus
messages: Nucleus

28377:LOC100557431
gene id: 28377:LOC100557431
uniprot id: G1KRG0
names: Similarity
messages: Belongs to the cytochrome P450 family.

28377:grik4
gene id: 28377:grik4
uniprot id: H9G757
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

28377:cryaa
gene id: 28377:cryaa
uniprot id: G1KUE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm

28377:ndufa5
gene id: 28377:ndufa5
uniprot id: A0A803TFZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

28377:eif2ak3
gene id: 28377:eif2ak3
uniprot id: G1KAG9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

28377:stac2
gene id: 28377:stac2
uniprot id: G1KTZ5
names: Subcellular Location Annotation
messages: sarcolemma

28377:echdc2
gene id: 28377:echdc2
uniprot id: G1KHT5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

28377:LOC100565755
gene id: 28377:LOC100565755
uniprot id: G1KM15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

28377:toe1
gene id: 28377:toe1
uniprot id: G1KQR3
names: Similarity
messages: Belongs to the CAF1 family.

28377:sod2
gene id: 28377:sod2
uniprot id: G1KCW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homotetramer.
messages: Mitochondrion matrix

28377:mrpl10
gene id: 28377:mrpl10
uniprot id: G1KFV8
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

28377:kctd20
gene id: 28377:kctd20
uniprot id: G1KST3
names: Subcellular Location Annotation
messages: Cytoplasm

28377:nnt
gene id: 28377:nnt
uniprot id: A0A803TAX5
uniprot id: G1KKU9
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

28377:tmc8
gene id: 28377:tmc8
uniprot id: G1KT29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

28377:hpse2
gene id: 28377:hpse2
uniprot id: G1KBY9
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

28377:LOC100557938
gene id: 28377:LOC100557938
uniprot id: A0A803T919
names: Similarity
messages: Belongs to the ohanin/vespryn family.

28377:ccdc130
gene id: 28377:ccdc130
uniprot id: G1KIL0
names: Similarity
messages: Belongs to the CWC16 family.

28377:LOC100553366
gene id: 28377:LOC100553366
uniprot id: R4GDG1
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

28377:tmem19
gene id: 28377:tmem19
uniprot id: G1KGJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

28377:atg16l1
gene id: 28377:atg16l1
uniprot id: A0A803TQB0
uniprot id: G1KF02
uniprot id: R4G9G5
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

28377:fgfr2
gene id: 28377:fgfr2
uniprot id: A0A803T6X6
uniprot id: G1KTN6
uniprot id: R4GC14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Membrane

28377:erg
gene id: 28377:erg
uniprot id: G1KIN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

28377:sgcg
gene id: 28377:sgcg
uniprot id: G1KBF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: cytoskeleton
messages: sarcolemma

28377:gabra2
gene id: 28377:gabra2
uniprot id: G1KG07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: dendrite

28377:ankzf1
gene id: 28377:ankzf1
uniprot id: G1KND4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

28377:pdcd4
gene id: 28377:pdcd4
uniprot id: G1KRL9
names: Similarity
messages: Belongs to the PDCD4 family.

28377:fam53b
gene id: 28377:fam53b
uniprot id: G1KPU2
names: Similarity
messages: Belongs to the FAM53 family.

28377:gnmt
gene id: 28377:gnmt
uniprot id: G1KEE2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.

28377:galr1
gene id: 28377:galr1
uniprot id: G1KE48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

28377:ipo7
gene id: 28377:ipo7
uniprot id: G1KIZ4
names: Subcellular Location Annotation
messages: Cytoplasm

28377:peli1
gene id: 28377:peli1
uniprot id: A0A803U030
names: Similarity
messages: Belongs to the pellino family.

28377:stk32a
gene id: 28377:stk32a
uniprot id: G1KPZ0
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:tbcc
gene id: 28377:tbcc
uniprot id: G1K8N1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCC family.
messages: Cytoplasm
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.

28377:dmrt2
gene id: 28377:dmrt2
uniprot id: G1KAN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

28377:casp6
gene id: 28377:casp6
uniprot id: G1KMX0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C14A family.
messages: Cytoplasm
messages: Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (Caspase-6 subunit p18) and a 11 kDa (Caspase-6 subunit p11) subunit.
messages: Nucleus

28377:spag9
gene id: 28377:spag9
uniprot id: G1KAB2
uniprot id: R4GBD4
names: Similarity
messages: Belongs to the JIP scaffold family.

28377:ezh1
gene id: 28377:ezh1
uniprot id: A0A803SVE4
uniprot id: G1KPU3
names: Subcellular Location Annotation
messages: Nucleus

28377:nt5dc3
gene id: 28377:nt5dc3
uniprot id: A0A803SPE1
uniprot id: G1KSF7
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

28377:prkcd
gene id: 28377:prkcd
uniprot id: G1KHZ5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

28377:tmsb4x
gene id: 28377:tmsb4x
uniprot id: A0A803STT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

28377:ccne2
gene id: 28377:ccne2
uniprot id: G1KCG6
names: Similarity
messages: Belongs to the cyclin family. Cyclin E subfamily.

28377:pla2g15
gene id: 28377:pla2g15
uniprot id: A0A803SWS5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

28377:map3k12
gene id: 28377:map3k12
uniprot id: G1K8Z9
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: May be an activator of the JNK/SAPK pathway.

28377:dclre1b
gene id: 28377:dclre1b
uniprot id: A0A803TBP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

28377:pgf
gene id: 28377:pgf
uniprot id: A0A803SMR1
uniprot id: A0A803TL04
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

28377:fam110b
gene id: 28377:fam110b
uniprot id: G1KDW0
names: Similarity
messages: Belongs to the FAM110 family.

28377:LOC100556911
gene id: 28377:LOC100556911
uniprot id: H9GL58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

28377:mcm3
gene id: 28377:mcm3
uniprot id: G1KDS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

28377:LOC100559713
gene id: 28377:LOC100559713
uniprot id: G1KNC9
names: Similarity
messages: Belongs to the cytochrome P450 family.

28377:wbp4
gene id: 28377:wbp4
uniprot id: G1K8U7
names: Subcellular Location Annotation
messages: Nucleus

28377:ube2b
gene id: 28377:ube2b
uniprot id: G1KAU9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

28377:gadd45gip1
gene id: 28377:gadd45gip1
uniprot id: G1KTI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
messages: Belongs to the mitochondrion-specific ribosomal protein mL64 family.
messages: Mitochondrion
messages: Nucleus

28377:LOC100560189
gene id: 28377:LOC100560189
uniprot id: R4GBA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

28377:pdcd10
gene id: 28377:pdcd10
uniprot id: G1KUG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

28377:snx18
gene id: 28377:snx18
uniprot id: G1KR67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

28377:lgr5
gene id: 28377:lgr5
uniprot id: G1KGE4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28377:slc10a2
gene id: 28377:slc10a2
uniprot id: G1KB29
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane
messages: Monomer and homodimer.

28377:trpc6
gene id: 28377:trpc6
uniprot id: G1KMX6
names: Subcellular Location Annotation
messages: Membrane

28377:rad54l2
gene id: 28377:rad54l2
uniprot id: G1KRR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

28377:lamb3
gene id: 28377:lamb3
uniprot id: G1KEN9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:c8b
gene id: 28377:c8b
uniprot id: A0A803SQ81
uniprot id: G1KFX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:adam12
gene id: 28377:adam12
uniprot id: G1K8S9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:mcmbp
gene id: 28377:mcmbp
uniprot id: G1KTJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCMBP family.
messages: Nucleus

28377:LOC100563651
gene id: 28377:LOC100563651
uniprot id: G1K9S4
names: Function
names: Similarity
messages: Belongs to the queuosine salvage protein family.
messages: Involved in salvaging queuosine.

28377:smim8
gene id: 28377:smim8
uniprot id: G1KQS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM8 family.
messages: Membrane

28377:msl3
gene id: 28377:msl3
uniprot id: G1K9H5
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC100561433
gene id: 28377:LOC100561433
uniprot id: G1KMJ3
names: Similarity
messages: Belongs to the peptidase M10A family.

28377:ccng1
gene id: 28377:ccng1
uniprot id: G1KQ42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin G subfamily.
messages: May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.
messages: Nucleus

28377:acad9
gene id: 28377:acad9
uniprot id: G1KN90
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

28377:arhgdib
gene id: 28377:arhgdib
uniprot id: G1KKK5
names: Similarity
messages: Belongs to the Rho GDI family.

28377:gabrg1
gene id: 28377:gabrg1
uniprot id: G1KWC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

28377:ggt7
gene id: 28377:ggt7
uniprot id: G1KJ41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

28377:myod1
gene id: 28377:myod1
uniprot id: A0A803U034
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

28377:ate1
gene id: 28377:ate1
uniprot id: A0A803TB07
uniprot id: A0A803TJ95
uniprot id: A0A803TPU5
names: Function
names: Similarity
messages: Belongs to the R-transferase family.
messages: Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.

28377:vldlr
gene id: 28377:vldlr
uniprot id: A0A803SME3
uniprot id: G1KBI9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: clathrin-coated pit

28377:fam134b
gene id: 28377:fam134b
uniprot id: A0A803TJN1
uniprot id: G1K8F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Membrane

28377:smpd2
gene id: 28377:smpd2
uniprot id: A0A803TWA1
uniprot id: G1KIQ0
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

28377:LOC100558643
gene id: 28377:LOC100558643
uniprot id: G1KRP7
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

28377:chrna9
gene id: 28377:chrna9
uniprot id: G1KLI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

28377:cpxm2
gene id: 28377:cpxm2
uniprot id: G1KU22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

28377:vps36
gene id: 28377:vps36
uniprot id: G1KT38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

28377:oca2
gene id: 28377:oca2
uniprot id: G1KKX6
names: Subcellular Location Annotation
messages: Membrane

28377:prom1
gene id: 28377:prom1
uniprot id: A0A803SU19
uniprot id: G1KMB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

28377:twf2
gene id: 28377:twf2
uniprot id: G1KFM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

28377:LOC100553170
gene id: 28377:LOC100553170
uniprot id: A0A803TUI8
names: Similarity
messages: Belongs to the ohanin/vespryn family.

28377:rpl10a
gene id: 28377:rpl10a
uniprot id: G1KIW5
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

28377:cdh2
gene id: 28377:cdh2
uniprot id: G1KKW9
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

28377:btf3l4
gene id: 28377:btf3l4
uniprot id: A0A803TWR6
names: Similarity
messages: Belongs to the NAC-beta family.

28377:ccdc85a
gene id: 28377:ccdc85a
uniprot id: G1KCF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

28377:tctn2
gene id: 28377:tctn2
uniprot id: A0A803TX16
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

28377:znrd1
gene id: 28377:znrd1
uniprot id: G1KL81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
messages: nucleolus

28377:gata1
gene id: 28377:gata1
uniprot id: G1KH54
names: Subcellular Location Annotation
messages: Nucleus

28377:tspo2
gene id: 28377:tspo2
uniprot id: A0A803SYB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

28377:ascc3
gene id: 28377:ascc3
uniprot id: G1KJW3
names: Similarity
messages: Belongs to the helicase family.

28377:nol8
gene id: 28377:nol8
uniprot id: A0A803T5G0
names: Subcellular Location Annotation
messages: nucleolus

28377:tube1
gene id: 28377:tube1
uniprot id: G1KLK0
names: Similarity
messages: Belongs to the tubulin family.

28377:dock10
gene id: 28377:dock10
uniprot id: A0A803TTX4
uniprot id: G1KCG2
uniprot id: R4GCF5
names: Similarity
messages: Belongs to the DOCK family.

28377:pm20d2
gene id: 28377:pm20d2
uniprot id: G1KQ65
names: Similarity
messages: Belongs to the peptidase M20A family.

28377:esyt3
gene id: 28377:esyt3
uniprot id: G1KJ31
names: Subcellular Location Annotation
messages: Membrane

28377:cks2
gene id: 28377:cks2
uniprot id: G1KSS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

28377:tspan1
gene id: 28377:tspan1
uniprot id: R4G9D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

28377:ccdc90b
gene id: 28377:ccdc90b
uniprot id: G1K9I2
names: Similarity
messages: Belongs to the CCDC90 family.

28377:kcns1
gene id: 28377:kcns1
uniprot id: G1KM14
names: Subcellular Location Annotation
messages: Membrane

28377:dph2
gene id: 28377:dph2
uniprot id: G1KPS5
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

28377:psmg2
gene id: 28377:psmg2
uniprot id: G1KNR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

28377:nploc4
gene id: 28377:nploc4
uniprot id: G1KQR1
names: Similarity
messages: Belongs to the NPL4 family.

28377:LOC100554736
gene id: 28377:LOC100554736
uniprot id: G1KN45
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse
messages: axon
messages: dendrite

28377:lrrc8c
gene id: 28377:lrrc8c
uniprot id: G1K985
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

28377:LOC103279179
gene id: 28377:LOC103279179
uniprot id: A0A803THP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zona pellucida-binding protein Sp38 family.
messages: Secreted

28377:tnfrsf21
gene id: 28377:tnfrsf21
uniprot id: G1KNP9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:spop
gene id: 28377:spop
uniprot id: G1KDC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tdpoz family.
messages: Nucleus speckle

28377:nsun4
gene id: 28377:nsun4
uniprot id: A0A803SL53
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

28377:LOC100556885
gene id: 28377:LOC100556885
uniprot id: G1KPP1
names: Similarity
messages: Belongs to the NipSnap family.

28377:extl2
gene id: 28377:extl2
uniprot id: G1KBJ7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

28377:utp18
gene id: 28377:utp18
uniprot id: G1KAS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

28377:dr1
gene id: 28377:dr1
uniprot id: G1KE76
names: Similarity
messages: Belongs to the NC2 beta/DR1 family.

28377:ak3
gene id: 28377:ak3
uniprot id: G1KC24
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

28377:uba7
gene id: 28377:uba7
uniprot id: G1KGJ3
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

28377:gcat
gene id: 28377:gcat
uniprot id: G1KR54
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

28377:slc25a19
gene id: 28377:slc25a19
uniprot id: G1KFF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

28377:gpbp1
gene id: 28377:gpbp1
uniprot id: G1KQ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

28377:ppp2ca
gene id: 28377:ppp2ca
uniprot id: H9G796
names: Similarity
messages: Belongs to the PPP phosphatase family.

28377:gnpda2
gene id: 28377:gnpda2
uniprot id: G1KG22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

28377:mgmt
gene id: 28377:mgmt
uniprot id: A0A803SV62
names: Function
names: Similarity
messages: Belongs to the MGMT family.
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

28377:mrpl23
gene id: 28377:mrpl23
uniprot id: G1KJ71
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

28377:kpna5
gene id: 28377:kpna5
uniprot id: G1KPI9
names: Similarity
messages: Belongs to the importin alpha family.

28377:itgb1
gene id: 28377:itgb1
uniprot id: A0A803T2U2
uniprot id: G1KFZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Melanosome
messages: Membrane
messages: invadopodium membrane
messages: lamellipodium
messages: ruffle membrane

28377:ssr4
gene id: 28377:ssr4
uniprot id: G1KL41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-delta family.
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

28377:cwc15
gene id: 28377:cwc15
uniprot id: G1KPD7
names: Similarity
messages: Belongs to the CWC15 family.

28377:LOC100556626
gene id: 28377:LOC100556626
uniprot id: G1KHS3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

28377:hspa4
gene id: 28377:hspa4
uniprot id: G1KNK5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

28377:dlx5
gene id: 28377:dlx5
uniprot id: G1KQ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

28377:ruvbl1
gene id: 28377:ruvbl1
uniprot id: G1KGA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

28377:LOC100559122
gene id: 28377:LOC100559122
uniprot id: A0A803U0A4
uniprot id: G1KUV2
names: Similarity
messages: Belongs to the ohanin/vespryn family.

28377:pde3a
gene id: 28377:pde3a
uniprot id: G1KU23
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

28377:LOC100555997
gene id: 28377:LOC100555997
uniprot id: R4GB47
names: Similarity
messages: Belongs to the MS4A family.

28377:olfml3
gene id: 28377:olfml3
uniprot id: A0A803T162
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OLFML3 family.
messages: Secreted

28377:lrp5
gene id: 28377:lrp5
uniprot id: G1KQ71
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDLR family.
messages: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes.
messages: Homodimer; disulfide-linked. Forms phosphorylated oligomer aggregates on Wnt-signaling.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:hexim1
gene id: 28377:hexim1
uniprot id: G1KSF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEXIM family.
messages: Nucleus

28377:LOC100562622
gene id: 28377:LOC100562622
uniprot id: R4G9J2
names: Similarity
messages: Belongs to the cornifelin family.

28377:jph2
gene id: 28377:jph2
uniprot id: G1KT07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

28377:slc7a6os
gene id: 28377:slc7a6os
uniprot id: H9GG60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWR1/SLC7A6OS family.
messages: Cytoplasm
messages: Directs RNA polymerase II nuclear import.
messages: Nucleus

28377:LOC100558328
gene id: 28377:LOC100558328
uniprot id: R4GC13
names: Similarity
messages: Belongs to the ohanin/vespryn family.

28377:tek
gene id: 28377:tek
uniprot id: G1KU09
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:mrpl19
gene id: 28377:mrpl19
uniprot id: A0A803TTE4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

28377:snf8
gene id: 28377:snf8
uniprot id: A0A803THN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

28377:LOC100553037
gene id: 28377:LOC100553037
uniprot id: R4GBV1
names: Subunit
messages: Monomer.

28377:camsap3
gene id: 28377:camsap3
uniprot id: G1KVF4
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

28377:LOC100564988
gene id: 28377:LOC100564988
uniprot id: A0A803TGI1
names: Similarity
messages: Belongs to the centrin family.

28377:ppp2r3c
gene id: 28377:ppp2r3c
uniprot id: G1KA76
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

28377:tmbim6
gene id: 28377:tmbim6
uniprot id: G1KIA1
uniprot id: G1KZB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

28377:hoxb4
gene id: 28377:hoxb4
uniprot id: G1KFF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

28377:LOC100564911
gene id: 28377:LOC100564911
uniprot id: G1K9V7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

28377:sgsh
gene id: 28377:sgsh
uniprot id: G1KRH7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

28377:cds1
gene id: 28377:cds1
uniprot id: G1KL44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

28377:trhr
gene id: 28377:trhr
uniprot id: G1KK31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

28377:inpp5a
gene id: 28377:inpp5a
uniprot id: G1KEM1
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

28377:sgcz
gene id: 28377:sgcz
uniprot id: G1KE54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

28377:LOC100560662
gene id: 28377:LOC100560662
uniprot id: A0A803T8B7
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

28377:tada1
gene id: 28377:tada1
uniprot id: G1KR84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TADA1 family.
messages: Nucleus
messages: Probably involved in transcriptional regulation.

28377:gtpbp10
gene id: 28377:gtpbp10
uniprot id: G1KRQ6
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

28377:scn4a
gene id: 28377:scn4a
uniprot id: G1KMZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

28377:pus7l
gene id: 28377:pus7l
uniprot id: G1KBG1
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

28377:hibch
gene id: 28377:hibch
uniprot id: G1K8R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
messages: Mitochondrion

28377:cdk5rap3
gene id: 28377:cdk5rap3
uniprot id: G1KFP2
names: Similarity
messages: Belongs to the CDK5RAP3 family.

28377:LOC100552377
gene id: 28377:LOC100552377
uniprot id: A0A803T3I0
names: Subcellular Location Annotation
messages: Membrane

28377:atf4
gene id: 28377:atf4
uniprot id: G1KGS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

28377:phc1
gene id: 28377:phc1
uniprot id: G1KTY4
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC100562609
gene id: 28377:LOC100562609
uniprot id: G1KG25
names: Similarity
messages: Belongs to the peptidase M14 family.

28377:htr5a
gene id: 28377:htr5a
uniprot id: G1KKP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:polr3b
gene id: 28377:polr3b
uniprot id: G1KR53
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

28377:lsm14b
gene id: 28377:lsm14b
uniprot id: A0A803T3X9
uniprot id: G1KSA2
names: Similarity
messages: Belongs to the LSM14 family.

28377:ins
gene id: 28377:ins
uniprot id: G1KJA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

28377:tmem106c
gene id: 28377:tmem106c
uniprot id: A0A803T5Z9
uniprot id: G1KNT8
names: Similarity
messages: Belongs to the TMEM106 family.

28377:slc26a7
gene id: 28377:slc26a7
uniprot id: G1KBS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

28377:LOC100567116
gene id: 28377:LOC100567116
uniprot id: A0A803TQX0
uniprot id: G1K9E5
names: Similarity
messages: Belongs to the peptidase C2 family.

28377:tcp11l1
gene id: 28377:tcp11l1
uniprot id: G1KB66
names: Similarity
messages: Belongs to the TCP11 family.

28377:mocs2
gene id: 28377:mocs2
uniprot id: G1KCD1
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.
messages: Belongs to the MoaD family. MOCS2A subfamily.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: This protein is produced by a bicistronic gene which also produces the large subunit (MOCS2B).
messages: cytosol

28377:chst14
gene id: 28377:chst14
uniprot id: G1KVL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

28377:parp1
gene id: 28377:parp1
uniprot id: G1KFB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Chromosome
messages: Nucleus
messages: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.

28377:btg2
gene id: 28377:btg2
uniprot id: G1KJJ2
names: Similarity
messages: Belongs to the BTG family.

28377:plekha8
gene id: 28377:plekha8
uniprot id: R4GC20
names: Subcellular Location Annotation
messages: Membrane
messages: trans-Golgi network membrane

28377:LOC100555256
gene id: 28377:LOC100555256
uniprot id: G1KJG4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:mknk1
gene id: 28377:mknk1
uniprot id: G1K9Z6
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:asz1
gene id: 28377:asz1
uniprot id: G1KHF2
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with DDX4, PIWIL1, RANBP9 and TDRD1.

28377:l1cam
gene id: 28377:l1cam
uniprot id: A0A803SND1
uniprot id: A0A803SR05
uniprot id: G1KLK3
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

28377:yipf7
gene id: 28377:yipf7
uniprot id: G1KG47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

28377:tysnd1
gene id: 28377:tysnd1
uniprot id: G1K9F7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1B family.
messages: Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
messages: Peroxisome
messages: The full-lengh TYSND1 is the active the proteolytic processing of PTS1- and PTS2-proteins and in self-cleavage, and intermolecular self-cleavage of TYSND1 down-regulates its protease activity.

28377:cdc37
gene id: 28377:cdc37
uniprot id: G1KI32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

28377:actr5
gene id: 28377:actr5
uniprot id: G1KPJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family. ARP5 subfamily.
messages: Nucleus

28377:itga8
gene id: 28377:itga8
uniprot id: G1KSU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

28377:myo10
gene id: 28377:myo10
uniprot id: A0A803SNS8
uniprot id: G1K8Y4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

28377:LOC100568117
gene id: 28377:LOC100568117
uniprot id: R4GBL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNF-like-inhibitor family.
messages: Secreted

28377:LOC100559577
gene id: 28377:LOC100559577
uniprot id: A0A803TH58
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

28377:c1h14orf169
gene id: 28377:c1h14orf169
uniprot id: A0A803SWF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family. NO66 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
messages: nucleolus

28377:LOC100566080
gene id: 28377:LOC100566080
uniprot id: G1KFV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:syndig1
gene id: 28377:syndig1
uniprot id: G1K9I1
names: Similarity
messages: Belongs to the CD225/Dispanin family.

28377:LOC103278941
gene id: 28377:LOC103278941
uniprot id: G1KYY2
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

28377:steap2
gene id: 28377:steap2
uniprot id: G1KRT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

28377:kiaa1024l
gene id: 28377:kiaa1024l
uniprot id: G1K9G7
names: Similarity
messages: Belongs to the MINAR family.

28377:stx19
gene id: 28377:stx19
uniprot id: G1K8L2
names: Similarity
messages: Belongs to the syntaxin family.

28377:sh3bp5l
gene id: 28377:sh3bp5l
uniprot id: G1KXP0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

28377:pik3c3
gene id: 28377:pik3c3
uniprot id: A0A803TMD1
uniprot id: G1KPF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
messages: Midbody

28377:parp4
gene id: 28377:parp4
uniprot id: A0A803TIW7
uniprot id: G1K9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

28377:rab3b
gene id: 28377:rab3b
uniprot id: A0A803TDU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

28377:rnf157
gene id: 28377:rnf157
uniprot id: G1KHH4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

28377:phka2
gene id: 28377:phka2
uniprot id: A0A803TF64
uniprot id: G1KLN6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

28377:map3k10
gene id: 28377:map3k10
uniprot id: H9GJL5
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

28377:LOC100555971
gene id: 28377:LOC100555971
uniprot id: G1KWC5
names: Subcellular Location Annotation
messages: Membrane

28377:LOC100554472
gene id: 28377:LOC100554472
uniprot id: G1KWQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

28377:kif26a
gene id: 28377:kif26a
uniprot id: G1KKU6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

28377:vdr
gene id: 28377:vdr
uniprot id: G1KNX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

28377:slc43a1
gene id: 28377:slc43a1
uniprot id: G1KGB8
names: Subcellular Location Annotation
messages: Membrane

28377:numb
gene id: 28377:numb
uniprot id: A0A803SXF5
uniprot id: G1KS68
uniprot id: R4GAY9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Plays a role in the process of neurogenesis.

28377:cdc5l
gene id: 28377:cdc5l
uniprot id: G1KMZ5
names: Similarity
messages: Belongs to the CEF1 family.

28377:chst13
gene id: 28377:chst13
uniprot id: A0A803SZN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

28377:amd1
gene id: 28377:amd1
uniprot id: G1KKY9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.

28377:ruvbl2
gene id: 28377:ruvbl2
uniprot id: G1KMP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

28377:sae1
gene id: 28377:sae1
uniprot id: A0A803TQ31
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

28377:txnrd1
gene id: 28377:txnrd1
uniprot id: G1KRY9
names: Similarity
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.

28377:sephs1
gene id: 28377:sephs1
uniprot id: G1K913
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

28377:lss
gene id: 28377:lss
uniprot id: G1KDD4
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

28377:trappc2
gene id: 28377:trappc2
uniprot id: G1K9S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

28377:ddo
gene id: 28377:ddo
uniprot id: A0A803TTI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

28377:tac1
gene id: 28377:tac1
uniprot id: A0A803TFL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted
messages: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

28377:eif4e3
gene id: 28377:eif4e3
uniprot id: A0A803T2K3
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

28377:flt4
gene id: 28377:flt4
uniprot id: G1KRW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Membrane
messages: Nucleus

28377:slc25a22
gene id: 28377:slc25a22
uniprot id: R4GBV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

28377:LOC100558133
gene id: 28377:LOC100558133
uniprot id: G1KK72
names: Similarity
messages: Belongs to the ohanin/vespryn family.

28377:ezr
gene id: 28377:ezr
uniprot id: G1KD48
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

28377:plrg1
gene id: 28377:plrg1
uniprot id: G1KRH3
names: Similarity
messages: Belongs to the WD repeat PRL1/PRL2 family.

28377:mfn1
gene id: 28377:mfn1
uniprot id: G1KD85
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

28377:hcfc2
gene id: 28377:hcfc2
uniprot id: R4GAS0
names: Subcellular Location Annotation
messages: Nucleus

28377:susd1
gene id: 28377:susd1
uniprot id: A0A803SKM7
uniprot id: G1KYE4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:prkd3
gene id: 28377:prkd3
uniprot id: G1K9B8
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

28377:spx
gene id: 28377:spx
uniprot id: R4GAW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spexin family.
messages: Secreted

28377:lrrfip1
gene id: 28377:lrrfip1
uniprot id: A0A803SVN5
uniprot id: A0A803T179
names: Similarity
messages: Belongs to the LRRFIP family.

28377:entpd1
gene id: 28377:entpd1
uniprot id: G1KCT1
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

28377:ap1s2
gene id: 28377:ap1s2
uniprot id: A0A803SZX3
uniprot id: A0A803TFE5
uniprot id: G1KTG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

28377:yaf2
gene id: 28377:yaf2
uniprot id: A0A803TR09
uniprot id: G1KBM8
names: Subcellular Location Annotation
messages: Nucleus

28377:sox4
gene id: 28377:sox4
uniprot id: G1KZB1
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC103279322
gene id: 28377:LOC103279322
uniprot id: H9GQT4
names: Subcellular Location Annotation
messages: Nucleus

28377:tie1
gene id: 28377:tie1
uniprot id: G1KNK3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:spc24
gene id: 28377:spc24
uniprot id: A0A803TPC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC24 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

28377:c1h14orf159
gene id: 28377:c1h14orf159
uniprot id: G1KJE6
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

28377:gaa
gene id: 28377:gaa
uniprot id: G1KRW0
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:phactr3
gene id: 28377:phactr3
uniprot id: A0A803SVQ9
uniprot id: G1KC59
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

28377:ahcy
gene id: 28377:ahcy
uniprot id: G1KIL2
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

28377:mrps10
gene id: 28377:mrps10
uniprot id: G1K988
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Mitochondrion

28377:kcnmb1
gene id: 28377:kcnmb1
uniprot id: R4GAN8
names: Subcellular Location Annotation
messages: Membrane

28377:nifk
gene id: 28377:nifk
uniprot id: G1KD10
names: Subcellular Location Annotation
messages: nucleolus

28377:insig2
gene id: 28377:insig2
uniprot id: A0A803TSZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

28377:neu4
gene id: 28377:neu4
uniprot id: G1K8I1
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

28377:fgf18
gene id: 28377:fgf18
uniprot id: A0A803T3T2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

28377:pik3r1
gene id: 28377:pik3r1
uniprot id: A0A803TIM1
uniprot id: G1KSH1
uniprot id: R4GAH3
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

28377:fgfr4
gene id: 28377:fgfr4
uniprot id: G1KE82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Membrane

28377:borcs5
gene id: 28377:borcs5
uniprot id: G1KCT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS5 family.
messages: Lysosome membrane
messages: Membrane

28377:wdr82
gene id: 28377:wdr82
uniprot id: G1KFK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SWD2 family.
messages: Nucleus

28377:gramd1b
gene id: 28377:gramd1b
uniprot id: H9G9K2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:LOC100559330
gene id: 28377:LOC100559330
uniprot id: R4G965
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 18 family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Monomer.
messages: extracellular space

28377:ntf4
gene id: 28377:ntf4
uniprot id: G1KNJ6
names: Similarity
messages: Belongs to the NGF-beta family.

28377:LOC100553180
gene id: 28377:LOC100553180
uniprot id: G1KIY1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:LOC100567136
gene id: 28377:LOC100567136
uniprot id: G1KMC5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28377:LOC100551943
gene id: 28377:LOC100551943
uniprot id: A0A803TIY7
names: Similarity
messages: Belongs to the cytochrome P450 family.

28377:nfyb
gene id: 28377:nfyb
uniprot id: G1KS07
names: Function
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.

28377:LOC100552727
gene id: 28377:LOC100552727
uniprot id: A0A803TR14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

28377:atp6v0a2
gene id: 28377:atp6v0a2
uniprot id: H9GM07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

28377:ncoa2
gene id: 28377:ncoa2
uniprot id: G1KQR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

28377:maml3
gene id: 28377:maml3
uniprot id: G1KAG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

28377:cd36
gene id: 28377:cd36
uniprot id: G1KRS5
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the CD36 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: Membrane raft

28377:mtx3
gene id: 28377:mtx3
uniprot id: G1KSV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

28377:esrp2
gene id: 28377:esrp2
uniprot id: A0A803TWE2
uniprot id: H9GFU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESRP family.
messages: Nucleus

28377:rps6
gene id: 28377:rps6
uniprot id: G1KU84
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

28377:rrp1b
gene id: 28377:rrp1b
uniprot id: G1KUF1
names: Similarity
messages: Belongs to the RRP1 family.

28377:slc7a2
gene id: 28377:slc7a2
uniprot id: G1KFG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

28377:mdfic
gene id: 28377:mdfic
uniprot id: G1KFM4
names: Similarity
messages: Belongs to the MDFI family.

28377:nxpe3
gene id: 28377:nxpe3
uniprot id: A0A803TK30
uniprot id: G1KLU5
names: Similarity
messages: Belongs to the NXPE family.

28377:cc2d1a
gene id: 28377:cc2d1a
uniprot id: G1KRR0
names: Similarity
messages: Belongs to the CC2D1 family.

28377:acad11
gene id: 28377:acad11
uniprot id: G1K8S8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

28377:gphb5
gene id: 28377:gphb5
uniprot id: A0A803T788
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

28377:ggh
gene id: 28377:ggh
uniprot id: G1KT97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

28377:riok3
gene id: 28377:riok3
uniprot id: G1K8C9
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

28377:rpl5
gene id: 28377:rpl5
uniprot id: A0A803TC78
uniprot id: G1KCQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

28377:mrpl50
gene id: 28377:mrpl50
uniprot id: A0A803TXV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

28377:slc6a1
gene id: 28377:slc6a1
uniprot id: G1KJU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

28377:ift43
gene id: 28377:ift43
uniprot id: G1KTG5
names: Similarity
messages: Belongs to the IFT43 family.

28377:CYTB
gene id: 28377:CYTB
uniprot id: B3GT02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The cytochrome bc1 complex contains 3 respiratory subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and UQCRC2) and probably 6 low-molecular weight proteins.

28377:cldn11
gene id: 28377:cldn11
uniprot id: G1KS09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

28377:en2
gene id: 28377:en2
uniprot id: G1KKR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

28377:ca3
gene id: 28377:ca3
uniprot id: G1KY16
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

28377:immp1l
gene id: 28377:immp1l
uniprot id: G1KAB0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

28377:tubgcp3
gene id: 28377:tubgcp3
uniprot id: G1KFE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

28377:atp5c1
gene id: 28377:atp5c1
uniprot id: A0A803T1I5
uniprot id: G1KCP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

28377:ppp4r3a
gene id: 28377:ppp4r3a
uniprot id: G1KJ53
names: Similarity
messages: Belongs to the SMEK family.

28377:st6galnac1
gene id: 28377:st6galnac1
uniprot id: G1KHU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

28377:syk
gene id: 28377:syk
uniprot id: A0A803TC51
uniprot id: G1K8U5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

28377:ldlrad1
gene id: 28377:ldlrad1
uniprot id: G1KPG8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:cebpz
gene id: 28377:cebpz
uniprot id: G1K9H6
names: Similarity
messages: Belongs to the CBF/MAK21 family.

28377:foxn3
gene id: 28377:foxn3
uniprot id: A0A803T9F9
uniprot id: G1KMS5
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC100566534
gene id: 28377:LOC100566534
uniprot id: G1KBP0
names: Subcellular Location Annotation
messages: Nucleus

28377:scube3
gene id: 28377:scube3
uniprot id: A0A803TAJ7
uniprot id: G1KA86
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:gnaq
gene id: 28377:gnaq
uniprot id: G1KEY8
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

28377:ace2
gene id: 28377:ace2
uniprot id: G1KTF3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Membrane
messages: Secreted
messages: cilium

28377:acsf2
gene id: 28377:acsf2
uniprot id: G1KDS5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

28377:gem
gene id: 28377:gem
uniprot id: G1KC41
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

28377:sh3pxd2b
gene id: 28377:sh3pxd2b
uniprot id: A0A803SNN9
uniprot id: A0A803SPR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm
messages: podosome

28377:fam83c
gene id: 28377:fam83c
uniprot id: G1KE70
names: Similarity
messages: Belongs to the FAM83 family.

28377:tubgcp6
gene id: 28377:tubgcp6
uniprot id: G1KAD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: centrosome

28377:rfc5
gene id: 28377:rfc5
uniprot id: H9GNG0
names: Similarity
messages: Belongs to the activator 1 small subunits family.

28377:lhfpl2
gene id: 28377:lhfpl2
uniprot id: G1KMG6
names: Subcellular Location Annotation
messages: Membrane

28377:ergic3
gene id: 28377:ergic3
uniprot id: G1KEP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

28377:LOC103278110
gene id: 28377:LOC103278110
uniprot id: R4GB89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Nucleus

28377:psmc3
gene id: 28377:psmc3
uniprot id: G1KAN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

28377:gtdc1
gene id: 28377:gtdc1
uniprot id: A0A803SNW6
uniprot id: A0A803T476
uniprot id: G1KBG8
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.

28377:rpl9
gene id: 28377:rpl9
uniprot id: G1KGG6
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

28377:gprc5a
gene id: 28377:gprc5a
uniprot id: G1KKC9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28377:eif5a2
gene id: 28377:eif5a2
uniprot id: G1KS44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane

28377:mcoln1
gene id: 28377:mcoln1
uniprot id: G1KSG8
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

28377:mef2c
gene id: 28377:mef2c
uniprot id: A0A803T3R7
uniprot id: A0A803T4E6
uniprot id: A0A803THX0
uniprot id: G1K8K0
names: Subcellular Location Annotation
messages: Nucleus

28377:stk17a
gene id: 28377:stk17a
uniprot id: G1KU03
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:LOC100562756
gene id: 28377:LOC100562756
uniprot id: G1KII1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

28377:rad9a
gene id: 28377:rad9a
uniprot id: G1KHD3
names: Similarity
messages: Belongs to the rad9 family.

28377:atp2b1
gene id: 28377:atp2b1
uniprot id: A0A803TUD6
uniprot id: G1KM20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:prrt1
gene id: 28377:prrt1
uniprot id: G1KK97
names: Similarity
messages: Belongs to the CD225/Dispanin family.

28377:nav2
gene id: 28377:nav2
uniprot id: A0A803TZD4
names: Similarity
messages: Belongs to the Nav/unc-53 family.

28377:ptcd2
gene id: 28377:ptcd2
uniprot id: A0A803SN94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTCD2 family.
messages: Mitochondrion

28377:nfil3
gene id: 28377:nfil3
uniprot id: G1K8V6
names: Similarity
messages: Belongs to the bZIP family. NFIL3 subfamily.

28377:wnt5b
gene id: 28377:wnt5b
uniprot id: G1K857
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

28377:chmp4c
gene id: 28377:chmp4c
uniprot id: G1KP71
names: Similarity
messages: Belongs to the SNF7 family.

28377:tpra1
gene id: 28377:tpra1
uniprot id: G1KGQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

28377:adgrg2
gene id: 28377:adgrg2
uniprot id: G1KLX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

28377:LOC100562486
gene id: 28377:LOC100562486
uniprot id: G1KXR0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28377:msx2
gene id: 28377:msx2
uniprot id: G1KQK2
names: Subcellular Location Annotation
messages: Nucleus

28377:neurod6
gene id: 28377:neurod6
uniprot id: G1KJ70
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

28377:dact2
gene id: 28377:dact2
uniprot id: G1KHV8
names: Similarity
messages: Belongs to the dapper family.

28377:sat1
gene id: 28377:sat1
uniprot id: G1KGL8
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family.
messages: Homodimer.

28377:hook1
gene id: 28377:hook1
uniprot id: G1KGA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

28377:orc3
gene id: 28377:orc3
uniprot id: G1KQH7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC3 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.
messages: Nucleus

28377:srd5a2
gene id: 28377:srd5a2
uniprot id: A0A803U1D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

28377:shkbp1
gene id: 28377:shkbp1
uniprot id: H9G800
names: Similarity
messages: Belongs to the KCTD3 family.

28377:LOC100551729
gene id: 28377:LOC100551729
uniprot id: G1KQD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

28377:homer1
gene id: 28377:homer1
uniprot id: A0A803T0N5
uniprot id: G1KT14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

28377:hcn1
gene id: 28377:hcn1
uniprot id: G1KL10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

28377:atp5j
gene id: 28377:atp5j
uniprot id: G1KQE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

28377:fam69a
gene id: 28377:fam69a
uniprot id: A0A803SRJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

28377:scml2
gene id: 28377:scml2
uniprot id: G1KLD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

28377:slc35b1
gene id: 28377:slc35b1
uniprot id: G1KDE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

28377:sec23a
gene id: 28377:sec23a
uniprot id: G1KRP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

28377:fam135b
gene id: 28377:fam135b
uniprot id: G1KLX4
names: Similarity
messages: Belongs to the FAM135 family.

28377:LOC100565110
gene id: 28377:LOC100565110
uniprot id: G1KRT0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28377:itgb5
gene id: 28377:itgb5
uniprot id: G1KJY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

28377:fam69c
gene id: 28377:fam69c
uniprot id: G1KC64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

28377:LOC100564895
gene id: 28377:LOC100564895
uniprot id: A0A803TJ68
names: Subcellular Location Annotation
messages: Secreted

28377:LOC100563862
gene id: 28377:LOC100563862
uniprot id: G1KKW2
names: Subcellular Location Annotation
messages: Membrane

28377:dopey1
gene id: 28377:dopey1
uniprot id: A0A803TRJ0
uniprot id: G1KTQ9
names: Similarity
messages: Belongs to the dopey family.

28377:braf
gene id: 28377:braf
uniprot id: A0A803ST73
uniprot id: A0A803TT54
uniprot id: G1KL20
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

28377:lrp6
gene id: 28377:lrp6
uniprot id: G1KD13
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDLR family.
messages: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes.
messages: Homodimer; disulfide-linked. Forms phosphorylated oligomer aggregates on Wnt-signaling.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:nkx2-3
gene id: 28377:nkx2-3
uniprot id: A0A803TB06
names: Subcellular Location Annotation
messages: Nucleus

28377:slc39a13
gene id: 28377:slc39a13
uniprot id: G1KAR5
names: Subcellular Location Annotation
messages: Membrane

28377:LOC100553181
gene id: 28377:LOC100553181
uniprot id: G1KBV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

28377:tyro3
gene id: 28377:tyro3
uniprot id: G1KPQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

28377:nrdc
gene id: 28377:nrdc
uniprot id: G1KHA3
names: Similarity
messages: Belongs to the peptidase M16 family.

28377:sdad1
gene id: 28377:sdad1
uniprot id: G1KMV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

28377:pex5l
gene id: 28377:pex5l
uniprot id: A0A803TBH4
uniprot id: A0A803TZM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Cytoplasm
messages: Membrane

28377:slc35a3
gene id: 28377:slc35a3
uniprot id: G1KC60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

28377:LOC100566014
gene id: 28377:LOC100566014
uniprot id: G1KBQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

28377:ippk
gene id: 28377:ippk
uniprot id: G1KIF2
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 2 family.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

28377:nadsyn1
gene id: 28377:nadsyn1
uniprot id: G1KRU6
names: Similarity
names: Subunit
messages: Homohexamer.
messages: In the C-terminal section; belongs to the NAD synthetase family.

28377:plp2
gene id: 28377:plp2
uniprot id: R4GDD4
names: Subcellular Location Annotation
messages: Membrane

28377:atp2b4
gene id: 28377:atp2b4
uniprot id: A0A803SXC7
uniprot id: A0A803TCK8
uniprot id: G1KK12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:st6gal2
gene id: 28377:st6gal2
uniprot id: E4ZFG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

28377:slc22a3
gene id: 28377:slc22a3
uniprot id: G1KBW0
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

28377:mtch1
gene id: 28377:mtch1
uniprot id: R4GAF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

28377:mien1
gene id: 28377:mien1
uniprot id: G1KBY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

28377:eif4ebp2
gene id: 28377:eif4ebp2
uniprot id: G1KHQ0
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

28377:maf
gene id: 28377:maf
uniprot id: H9GW01
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

28377:lrp8
gene id: 28377:lrp8
uniprot id: A0A803TC95
uniprot id: G1KI88
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:bpgm
gene id: 28377:bpgm
uniprot id: A0A803TA28
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

28377:slc24a3
gene id: 28377:slc24a3
uniprot id: G1KDR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

28377:gria4
gene id: 28377:gria4
uniprot id: G1KLJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

28377:tdrd5
gene id: 28377:tdrd5
uniprot id: G1KVT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDRD5 family.
messages: Cytoplasm

28377:slc29a1
gene id: 28377:slc29a1
uniprot id: R4GAH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

28377:ctnna1
gene id: 28377:ctnna1
uniprot id: A0A803STG8
uniprot id: G1KSA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction
messages: cytoskeleton

28377:lamp1
gene id: 28377:lamp1
uniprot id: G1K8E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

28377:bag6
gene id: 28377:bag6
uniprot id: G1KM96
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Released extracellularly via exosomes, it is a ligand of the natural killer/NK cells receptor NCR3 and stimulates NK cells cytotoxicity. It may thereby trigger NK cells cytotoxicity against neighboring tumor cells and immature myeloid dendritic cells (DC).
messages: extracellular exosome

28377:LOC100558842
gene id: 28377:LOC100558842
uniprot id: A0A803TPR6
uniprot id: G1K916
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

28377:ap3b1
gene id: 28377:ap3b1
uniprot id: A0A803SMF1
uniprot id: G1KGW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

28377:zdhhc21
gene id: 28377:zdhhc21
uniprot id: G1KUE0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

28377:ss18l1
gene id: 28377:ss18l1
uniprot id: G1KS70
names: Similarity
messages: Belongs to the SS18 family.

28377:ets2
gene id: 28377:ets2
uniprot id: G1KIR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus
messages: Transcription factor.

28377:LOC100564389
gene id: 28377:LOC100564389
uniprot id: G1KMA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

28377:snx7
gene id: 28377:snx7
uniprot id: G1K8N3
names: Similarity
messages: Belongs to the sorting nexin family.

28377:atp2b2
gene id: 28377:atp2b2
uniprot id: A0A803T936
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:LOC100557158
gene id: 28377:LOC100557158
uniprot id: G1KCZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

28377:kcnk1
gene id: 28377:kcnk1
uniprot id: G1K923
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

28377:dock2
gene id: 28377:dock2
uniprot id: G1KSA0
names: Similarity
messages: Belongs to the DOCK family.

28377:paqr3
gene id: 28377:paqr3
uniprot id: G1KFE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

28377:LOC100562282
gene id: 28377:LOC100562282
uniprot id: R4GAL0
names: Subcellular Location Annotation
messages: Membrane

28377:ncoa7
gene id: 28377:ncoa7
uniprot id: A0A803TF29
uniprot id: G1KA58
names: Similarity
messages: Belongs to the OXR1 family.

28377:arhgef28
gene id: 28377:arhgef28
uniprot id: G1KIR4
names: Subcellular Location Annotation
messages: Cytoplasm

28377:dnpep
gene id: 28377:dnpep
uniprot id: G1KP81
names: Similarity
names: Subunit
messages: Belongs to the peptidase M18 family.
messages: Tetrahedron-shaped homododecamer built from six homodimers.

28377:sulf1
gene id: 28377:sulf1
uniprot id: A0A803SL44
uniprot id: G1KQZ3
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

28377:gclc
gene id: 28377:gclc
uniprot id: G1KHV4
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

28377:fam3c
gene id: 28377:fam3c
uniprot id: A0A803TT60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

28377:rhbdf2
gene id: 28377:rhbdf2
uniprot id: G1KHP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

28377:csgalnact1
gene id: 28377:csgalnact1
uniprot id: G1KIE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

28377:mdga1
gene id: 28377:mdga1
uniprot id: A0A803TBQ9
uniprot id: A0A803TJA0
uniprot id: R4GAC6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28377:adamts2
gene id: 28377:adamts2
uniprot id: G1KSQ7
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

28377:capza1
gene id: 28377:capza1
uniprot id: G1KUJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

28377:afap1l1
gene id: 28377:afap1l1
uniprot id: G1KR98
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in podosome and invadosome formation.
messages: invadopodium
messages: podosome

28377:pax3
gene id: 28377:pax3
uniprot id: G1KDH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

28377:ntng1
gene id: 28377:ntng1
uniprot id: A0A803STG9
uniprot id: A0A803SV50
uniprot id: A0A803T435
uniprot id: A0A803T5D7
uniprot id: A0A803TCD7
uniprot id: G1K9F5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:cldn20
gene id: 28377:cldn20
uniprot id: G1KDU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

28377:snx14
gene id: 28377:snx14
uniprot id: G1KR43
names: Similarity
messages: Belongs to the sorting nexin family.

28377:srpx
gene id: 28377:srpx
uniprot id: G1KQ90
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:prph2
gene id: 28377:prph2
uniprot id: G1K8N9
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

28377:pqlc1
gene id: 28377:pqlc1
uniprot id: A0A803T3E0
uniprot id: A0A803TNQ7
names: Subcellular Location Annotation
messages: Membrane

28377:erbb4
gene id: 28377:erbb4
uniprot id: G1KJS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

28377:mff
gene id: 28377:mff
uniprot id: A0A803SS56
uniprot id: G1KCL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

28377:fgd4
gene id: 28377:fgd4
uniprot id: G1KMM8
names: Subcellular Location Annotation
messages: cytoskeleton

28377:plxnb3
gene id: 28377:plxnb3
uniprot id: G1KHW4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:psme3
gene id: 28377:psme3
uniprot id: G1KP54
names: Similarity
messages: Belongs to the PA28 family.

28377:slc37a3
gene id: 28377:slc37a3
uniprot id: G1KMT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

28377:agtpbp1
gene id: 28377:agtpbp1
uniprot id: A0A803TX86
uniprot id: G1K8V2
uniprot id: G1KW25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

28377:ano9
gene id: 28377:ano9
uniprot id: G1KXW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

28377:fam83f
gene id: 28377:fam83f
uniprot id: G1KGI1
names: Similarity
messages: Belongs to the FAM83 family.

28377:elac2
gene id: 28377:elac2
uniprot id: G1KTV9
names: Similarity
messages: Belongs to the RNase Z family.

28377:LOC100559929
gene id: 28377:LOC100559929
uniprot id: R4GAI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

28377:hmx3
gene id: 28377:hmx3
uniprot id: G1KU04
names: Subcellular Location Annotation
messages: Nucleus

28377:mysm1
gene id: 28377:mysm1
uniprot id: G1KE68
names: Similarity
messages: Belongs to the peptidase M67A family. MYSM1 subfamily.

28377:LOC100561817
gene id: 28377:LOC100561817
uniprot id: G1KSC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:cdc37l1
gene id: 28377:cdc37l1
uniprot id: G1KC11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

28377:slc23a1
gene id: 28377:slc23a1
uniprot id: G1KSI6
names: Subcellular Location Annotation
messages: Membrane

28377:spdya
gene id: 28377:spdya
uniprot id: G1KIS1
names: Similarity
messages: Belongs to the Speedy/Ringo family.

28377:cga
gene id: 28377:cga
uniprot id: A0A803SMK5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Heterodimer of an alpha and a beta chain.
messages: Secreted

28377:coq6
gene id: 28377:coq6
uniprot id: G1KSA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
messages: Cell projection
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ7.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Golgi apparatus
messages: Mitochondrion inner membrane

28377:rcan1
gene id: 28377:rcan1
uniprot id: A0A803TDZ0
uniprot id: G1KDK3
names: Similarity
messages: Belongs to the RCAN family.

28377:tgfbr1
gene id: 28377:tgfbr1
uniprot id: G1KIM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: Secreted

28377:mastl
gene id: 28377:mastl
uniprot id: G1KHC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Nucleus
messages: centrosome

28377:haus3
gene id: 28377:haus3
uniprot id: G1KN52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS3 family.
messages: spindle

28377:gabrb2
gene id: 28377:gabrb2
uniprot id: A0A803T7J4
uniprot id: G1KQV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

28377:hif1a
gene id: 28377:hif1a
uniprot id: G1KSA4
names: Subcellular Location Annotation
messages: Cytoplasm

28377:nipa1
gene id: 28377:nipa1
uniprot id: G1KMN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

28377:psmc3ip
gene id: 28377:psmc3ip
uniprot id: G1KP46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

28377:pde8b
gene id: 28377:pde8b
uniprot id: G1KH36
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

28377:smc1b
gene id: 28377:smc1b
uniprot id: A0A803SKT6
uniprot id: A0A803T669
uniprot id: G1KQI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

28377:dus4l
gene id: 28377:dus4l
uniprot id: G1KQT0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

28377:fam98a
gene id: 28377:fam98a
uniprot id: G1KIY3
names: Similarity
messages: Belongs to the FAM98 family.

28377:gfap
gene id: 28377:gfap
uniprot id: A0A803TEM3
uniprot id: G1KGU4
names: Similarity
messages: Belongs to the intermediate filament family.

28377:b4galnt3
gene id: 28377:b4galnt3
uniprot id: G1K862
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

28377:rpa3
gene id: 28377:rpa3
uniprot id: G1KN66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

28377:diexf
gene id: 28377:diexf
uniprot id: G1K9D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP25 family.
messages: nucleolus

28377:pde4d
gene id: 28377:pde4d
uniprot id: A0A803TEX6
uniprot id: A0A803TQC2
uniprot id: G1KIP2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

28377:LOC100566088
gene id: 28377:LOC100566088
uniprot id: G1KGX8
names: Similarity
messages: Belongs to the intermediate filament family.

28377:rps13
gene id: 28377:rps13
uniprot id: G1K874
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

28377:lmod2
gene id: 28377:lmod2
uniprot id: G1K8X9
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

28377:ext2
gene id: 28377:ext2
uniprot id: G1KPS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

28377:aass
gene id: 28377:aass
uniprot id: A0A803TXH5
uniprot id: G1KFR3
names: Similarity
messages: In the C-terminal section; belongs to the saccharopine dehydrogenase family.
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

28377:cdk6
gene id: 28377:cdk6
uniprot id: G1KQY0
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:stxbp2
gene id: 28377:stxbp2
uniprot id: G1KTL2
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

28377:bod1
gene id: 28377:bod1
uniprot id: G1KQN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BOD1 family.
messages: centrosome
messages: kinetochore

28377:LOC100559860
gene id: 28377:LOC100559860
uniprot id: G1KST0
names: Similarity
messages: Belongs to the apolipoprotein L family.

28377:sult4a1
gene id: 28377:sult4a1
uniprot id: G1KSC5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

28377:dst
gene id: 28377:dst
uniprot id: A0A803TH08
names: Subcellular Location Annotation
messages: cytoskeleton

28377:scrn1
gene id: 28377:scrn1
uniprot id: G1K8W8
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

28377:nxph1
gene id: 28377:nxph1
uniprot id: G1KNG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

28377:adamts1
gene id: 28377:adamts1
uniprot id: G1KQ54
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

28377:csnk1a1
gene id: 28377:csnk1a1
uniprot id: A0A803TT69
uniprot id: G1KRF6
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:slc25a31
gene id: 28377:slc25a31
uniprot id: G1KLN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

28377:arl5b
gene id: 28377:arl5b
uniprot id: A0A803TYC3
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

28377:kcnc4
gene id: 28377:kcnc4
uniprot id: G1KMP2
names: Subcellular Location Annotation
messages: Membrane

28377:LOC100555417
gene id: 28377:LOC100555417
uniprot id: G1KUJ2
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

28377:tspan12
gene id: 28377:tspan12
uniprot id: G1KG80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

28377:wdyhv1
gene id: 28377:wdyhv1
uniprot id: G1KJ74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NTAQ1 family.
messages: Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
messages: Monomer.

28377:tor1aip2
gene id: 28377:tor1aip2
uniprot id: A0A803T9R0
uniprot id: G1K935
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

28377:rpl10
gene id: 28377:rpl10
uniprot id: G1KHH7
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

28377:tdrd3
gene id: 28377:tdrd3
uniprot id: A0A803T506
uniprot id: G1KDC8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins.

28377:il17rb
gene id: 28377:il17rb
uniprot id: G1KLE5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28377:tmem70
gene id: 28377:tmem70
uniprot id: G1KN55
names: Similarity
messages: Belongs to the TMEM70 family.

28377:LOC100553289
gene id: 28377:LOC100553289
uniprot id: A0A803TJ75
uniprot id: G1KID1
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

28377:cul3
gene id: 28377:cul3
uniprot id: G1KCQ3
names: Similarity
messages: Belongs to the cullin family.

28377:pou2f1
gene id: 28377:pou2f1
uniprot id: A0A803THI0
uniprot id: G1KJ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

28377:bdkrb2
gene id: 28377:bdkrb2
uniprot id: G1KNH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

28377:kcna2
gene id: 28377:kcna2
uniprot id: G1KUR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
messages: Cell membrane
messages: Membrane

28377:LOC100553034
gene id: 28377:LOC100553034
uniprot id: G1KYB1
names: Function
names: Similarity
messages: Belongs to the ficolin lectin family. Veficolin subfamily.
messages: Initiates complement activation and/or interferes in platelet aggregation and/or blood coagulation.

28377:slc10a3
gene id: 28377:slc10a3
uniprot id: G1KY98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

28377:map3k8
gene id: 28377:map3k8
uniprot id: G1KGS0
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

28377:ilvbl
gene id: 28377:ilvbl
uniprot id: G1KS36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPP enzyme family.
messages: Membrane

28377:hoxc9
gene id: 28377:hoxc9
uniprot id: G1KKM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

28377:hmces
gene id: 28377:hmces
uniprot id: G1KEX9
names: Function
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.
messages: Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction.

28377:myoz3
gene id: 28377:myoz3
uniprot id: A0A803SXW7
names: Similarity
messages: Belongs to the myozenin family.

28377:slc25a13
gene id: 28377:slc25a13
uniprot id: A0A803U1E6
uniprot id: G1KQ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

28377:etv6
gene id: 28377:etv6
uniprot id: G1KD30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

28377:dusp16
gene id: 28377:dusp16
uniprot id: G1KCT0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

28377:amigo3
gene id: 28377:amigo3
uniprot id: G1KGZ3
names: Similarity
messages: Belongs to the immunoglobulin superfamily. AMIGO family.

28377:LOC100553910
gene id: 28377:LOC100553910
uniprot id: A0A803T295
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

28377:LOC100551807
gene id: 28377:LOC100551807
uniprot id: G1KKI8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.
messages: Belongs to the osteocalcin/matrix Gla protein family.
messages: Requires vitamin K-dependent gamma-carboxylation for its function.
messages: Secreted

28377:LOC100557088
gene id: 28377:LOC100557088
uniprot id: G1KYZ2
uniprot id: R4GAB8
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

28377:ND5
gene id: 28377:ND5
uniprot id: B3GT00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

28377:ddx4
gene id: 28377:ddx4
uniprot id: G1KQJ8
names: Similarity
messages: Belongs to the DEAD box helicase family.

28377:LOC100337546
gene id: 28377:LOC100337546
uniprot id: B6Z1W6
names: Similarity
messages: Belongs to the intermediate filament family.

28377:LOC100565304
gene id: 28377:LOC100565304
uniprot id: G1KJ99
names: Subcellular Location Annotation
messages: Nucleus

28377:cpeb4
gene id: 28377:cpeb4
uniprot id: A0A803SUH2
uniprot id: G1KQM8
names: Similarity
messages: Belongs to the RRM CPEB family.

28377:LOC100555397
gene id: 28377:LOC100555397
uniprot id: G1KQP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

28377:ada
gene id: 28377:ada
uniprot id: G1KT90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Cell junction
messages: Cell membrane
messages: Cytoplasmic vesicle lumen

28377:ergic1
gene id: 28377:ergic1
uniprot id: A0A803TG51
uniprot id: G1KQV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

28377:aacs
gene id: 28377:aacs
uniprot id: H9GLA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Converts acetoacetate to acetoacetyl-CoA in the cytosol.
messages: cytosol

28377:ppef1
gene id: 28377:ppef1
uniprot id: G1KLG7
names: Similarity
messages: Belongs to the PPP phosphatase family.

28377:pan2
gene id: 28377:pan2
uniprot id: R4GD02
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: P-body
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

28377:aqp5
gene id: 28377:aqp5
uniprot id: G1KHU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

28377:usp1
gene id: 28377:usp1
uniprot id: G1KH47
names: Similarity
messages: Belongs to the peptidase C19 family.

28377:hapln1
gene id: 28377:hapln1
uniprot id: G1KL49
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:cntnap1
gene id: 28377:cntnap1
uniprot id: G1KPM3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: paranodal septate junction

28377:rars
gene id: 28377:rars
uniprot id: A0A803TC76
uniprot id: G1KDF6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

28377:cpne8
gene id: 28377:cpne8
uniprot id: G1KH50
names: Similarity
messages: Belongs to the copine family.

28377:rln3
gene id: 28377:rln3
uniprot id: A0A803SY97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

28377:tbca
gene id: 28377:tbca
uniprot id: A0A803TYV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
messages: cytoskeleton

28377:elovl1
gene id: 28377:elovl1
uniprot id: G1KNR6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

28377:akirin2
gene id: 28377:akirin2
uniprot id: G1KQC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

28377:alcam
gene id: 28377:alcam
uniprot id: G1KFD3
names: Subcellular Location Annotation
messages: Cell membrane
messages: axon
messages: dendrite

28377:ltbp1
gene id: 28377:ltbp1
uniprot id: G1KIP0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

28377:mrps5
gene id: 28377:mrps5
uniprot id: G1K8V8
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

28377:tdo2
gene id: 28377:tdo2
uniprot id: G1KT95
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:ip6k2
gene id: 28377:ip6k2
uniprot id: G1K9X5
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

28377:kif27
gene id: 28377:kif27
uniprot id: G1K9W1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

28377:lyrm2
gene id: 28377:lyrm2
uniprot id: G1KPV5
names: Similarity
messages: Belongs to the complex I LYR family.

28377:cd14
gene id: 28377:cd14
uniprot id: G1KN28
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: Membrane raft
messages: Secreted

28377:LOC100566938
gene id: 28377:LOC100566938
uniprot id: G1KX50
names: Similarity
messages: Belongs to the peptidase A1 family.

28377:krt36
gene id: 28377:krt36
uniprot id: B6Z1W3
names: Similarity
messages: Belongs to the intermediate filament family.

28377:rpap2
gene id: 28377:rpap2
uniprot id: A0A803TE38
uniprot id: G1KCW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.

28377:tlr5
gene id: 28377:tlr5
uniprot id: G1KAR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

28377:rock1
gene id: 28377:rock1
uniprot id: G1KHH5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Homodimer.
messages: Membrane
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.

28377:LOC100563926
gene id: 28377:LOC100563926
uniprot id: G1KSQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

28377:dock6
gene id: 28377:dock6
uniprot id: G1KT35
names: Similarity
messages: Belongs to the DOCK family.

28377:ep300
gene id: 28377:ep300
uniprot id: G1KDQ6
names: Subcellular Location Annotation
messages: Cytoplasm

28377:gga3
gene id: 28377:gga3
uniprot id: G1KFC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

28377:prmt7
gene id: 28377:prmt7
uniprot id: H9GG55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

28377:hmga1
gene id: 28377:hmga1
uniprot id: G1KRT7
uniprot id: G1KY66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGA family.
messages: Nucleus

28377:syn3
gene id: 28377:syn3
uniprot id: A0A803TIJ2
names: Similarity
messages: Belongs to the synapsin family.

28377:uts2r
gene id: 28377:uts2r
uniprot id: G1KL43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

28377:smco4
gene id: 28377:smco4
uniprot id: G1KQ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMCO4 family.
messages: Membrane

28377:xpc
gene id: 28377:xpc
uniprot id: A0A803STU8
uniprot id: G1KNY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPC family.
messages: Nucleus

28377:tcp11l2
gene id: 28377:tcp11l2
uniprot id: G1KR74
names: Similarity
messages: Belongs to the TCP11 family.

28377:ppp1r12a
gene id: 28377:ppp1r12a
uniprot id: A0A803SXD0
uniprot id: A0A803THU1
uniprot id: A0A803TVQ8
uniprot id: G1KPJ2
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.

28377:LOC103278888
gene id: 28377:LOC103278888
uniprot id: A0A803TTX2
names: Similarity
messages: Belongs to the CRISP family.

28377:pdgfrb
gene id: 28377:pdgfrb
uniprot id: G1KR75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Membrane

28377:cartpt
gene id: 28377:cartpt
uniprot id: G1KJH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

28377:rspo2
gene id: 28377:rspo2
uniprot id: G1KJT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-spondin family.
messages: Secreted

28377:LOC100560301
gene id: 28377:LOC100560301
uniprot id: G1KJ64
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

28377:rapsn
gene id: 28377:rapsn
uniprot id: G1KAG0
names: Similarity
messages: Belongs to the RAPsyn family.

28377:slc15a2
gene id: 28377:slc15a2
uniprot id: A0A803SVT4
uniprot id: G1KDE4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

28377:LOC100563136
gene id: 28377:LOC100563136
uniprot id: R4G9Q4
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

28377:capza3
gene id: 28377:capza3
uniprot id: G1KU75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

28377:sfmbt2
gene id: 28377:sfmbt2
uniprot id: G1KDI2
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC100565027
gene id: 28377:LOC100565027
uniprot id: R4G9G9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

28377:LOC100560224
gene id: 28377:LOC100560224
uniprot id: G1KC28
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

28377:cd151
gene id: 28377:cd151
uniprot id: G1KR65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

28377:gtf2h1
gene id: 28377:gtf2h1
uniprot id: G1K887
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

28377:pdk3
gene id: 28377:pdk3
uniprot id: G1KG97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

28377:prox1
gene id: 28377:prox1
uniprot id: G1KF25
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC100567007
gene id: 28377:LOC100567007
uniprot id: H9GFI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

28377:nt5c3b
gene id: 28377:nt5c3b
uniprot id: G1KTJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

28377:parp9
gene id: 28377:parp9
uniprot id: G1KJ88
names: Similarity
messages: Belongs to the ARTD/PARP family.

28377:tspo
gene id: 28377:tspo
uniprot id: G1KRS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

28377:sft2d3
gene id: 28377:sft2d3
uniprot id: A0A803SPE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

28377:setd7
gene id: 28377:setd7
uniprot id: G1KAF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET7 subfamily.
messages: Chromosome
messages: Nucleus

28377:LOC100561568
gene id: 28377:LOC100561568
uniprot id: G1KT60
names: Similarity
messages: Belongs to the ARTD/PARP family.

28377:anxa3
gene id: 28377:anxa3
uniprot id: G1KFA2
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

28377:LOC100566860
gene id: 28377:LOC100566860
uniprot id: A0A803TER0
names: Similarity
names: Subunit
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
messages: Interacts with PDZK1.

28377:slc9a8
gene id: 28377:slc9a8
uniprot id: G1KRI9
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

28377:cln8
gene id: 28377:cln8
uniprot id: G1KDQ2
names: Subcellular Location Annotation
messages: Membrane

28377:prokr1
gene id: 28377:prokr1
uniprot id: G1K8T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

28377:fbxl5
gene id: 28377:fbxl5
uniprot id: A0A803SM02
names: Subcellular Location Annotation
messages: perinuclear region

28377:mtmr7
gene id: 28377:mtmr7
uniprot id: G1KFD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

28377:LOC100557236
gene id: 28377:LOC100557236
uniprot id: A0A803STF3
names: Similarity
messages: Belongs to the cytochrome P450 family.

28377:ppara
gene id: 28377:ppara
uniprot id: G1KD82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

28377:ndufaf1
gene id: 28377:ndufaf1
uniprot id: G1KXZ2
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

28377:rab3gap2
gene id: 28377:rab3gap2
uniprot id: G1K9V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP regulatory subunit family.
messages: Cytoplasm

28377:clvs2
gene id: 28377:clvs2
uniprot id: G1K9P4
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network membrane

28377:atg4c
gene id: 28377:atg4c
uniprot id: G1KHE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

28377:acss3
gene id: 28377:acss3
uniprot id: G1KPY7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

28377:laptm4b
gene id: 28377:laptm4b
uniprot id: G1KRY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAPTM4/LAPTM5 transporter family.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: multivesicular body lumen
messages: multivesicular body membrane

28377:sptbn4
gene id: 28377:sptbn4
uniprot id: H9G7V0
names: Similarity
messages: Belongs to the spectrin family.

28377:tsr2
gene id: 28377:tsr2
uniprot id: A0A803T7C1
names: Function
names: Similarity
messages: Belongs to the TSR2 family.
messages: May be involved in 20S pre-rRNA processing.

28377:chmp2b
gene id: 28377:chmp2b
uniprot id: A0A803SQP3
names: Similarity
messages: Belongs to the SNF7 family.

28377:clk4
gene id: 28377:clk4
uniprot id: A0A803SWY5
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:zadh2
gene id: 28377:zadh2
uniprot id: G1KDW9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

28377:tcn1
gene id: 28377:tcn1
uniprot id: G1KJJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

28377:tyk2
gene id: 28377:tyk2
uniprot id: G1KHZ7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.

28377:dusp5
gene id: 28377:dusp5
uniprot id: G1KEU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

28377:bmp3
gene id: 28377:bmp3
uniprot id: G1KJS6
names: Similarity
messages: Belongs to the TGF-beta family.

28377:adamts5
gene id: 28377:adamts5
uniprot id: G1KPY2
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

28377:LOC100565626
gene id: 28377:LOC100565626
uniprot id: G1KI31
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:mkx
gene id: 28377:mkx
uniprot id: G1KH38
names: Subcellular Location Annotation
messages: Nucleus

28377:itga9
gene id: 28377:itga9
uniprot id: G1KJB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

28377:tspan2
gene id: 28377:tspan2
uniprot id: G1KBW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

28377:LOC100553373
gene id: 28377:LOC100553373
uniprot id: A0A803T3A9
names: Similarity
messages: Belongs to the cytochrome b5 family.

28377:pot1
gene id: 28377:pot1
uniprot id: G1K9A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the telombin family.
messages: Nucleus
messages: telomere

28377:lipg
gene id: 28377:lipg
uniprot id: G1KUM0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:samhd1
gene id: 28377:samhd1
uniprot id: G1KG42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAMHD1 family.
messages: Chromosome

28377:colec12
gene id: 28377:colec12
uniprot id: G1KHR4
names: Subcellular Location Annotation
messages: Secreted

28377:chl1
gene id: 28377:chl1
uniprot id: A0A803TET0
uniprot id: G1K9T3
uniprot id: R4GA37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

28377:ptpn3
gene id: 28377:ptpn3
uniprot id: G1KG45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

28377:habp4
gene id: 28377:habp4
uniprot id: G1KMY4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

28377:dars2
gene id: 28377:dars2
uniprot id: R4G9Q0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

28377:klc1
gene id: 28377:klc1
uniprot id: G1KKG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

28377:slc17a9
gene id: 28377:slc17a9
uniprot id: G1KE80
names: Subcellular Location Annotation
messages: Membrane

28377:scg5
gene id: 28377:scg5
uniprot id: G1KRQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 7B2 family.
messages: Secreted

28377:slc7a14
gene id: 28377:slc7a14
uniprot id: G1KS19
names: Subcellular Location Annotation
messages: Membrane

28377:hint1
gene id: 28377:hint1
uniprot id: A0A803T6X4
names: Similarity
messages: Belongs to the HINT family.

28377:LOC100565550
gene id: 28377:LOC100565550
uniprot id: A0A803SN84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

28377:tmprss2
gene id: 28377:tmprss2
uniprot id: G1KE28
names: Caution
names: Similarity
messages: Belongs to the peptidase S1 family. Snake venom subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:slc5a7
gene id: 28377:slc5a7
uniprot id: G1KAQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

28377:LOC100559528
gene id: 28377:LOC100559528
uniprot id: G1KBZ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 18 family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Monomer.
messages: extracellular space

28377:alas1
gene id: 28377:alas1
uniprot id: G1KFQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

28377:LOC100567780
gene id: 28377:LOC100567780
uniprot id: G1KMS7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

28377:psmd13
gene id: 28377:psmd13
uniprot id: G1KU14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S11 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

28377:dock1
gene id: 28377:dock1
uniprot id: G1KGL2
names: Similarity
messages: Belongs to the DOCK family.

28377:asic1
gene id: 28377:asic1
uniprot id: A0A803TTZ0
uniprot id: G1KTF6
names: Subcellular Location Annotation
messages: Membrane

28377:LOC100567926
gene id: 28377:LOC100567926
uniprot id: H9GS66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Membrane
messages: Microsome membrane

28377:LOC103278061
gene id: 28377:LOC103278061
uniprot id: R4GD95
names: Similarity
messages: Belongs to the ohanin/vespryn family.

28377:hs2st1
gene id: 28377:hs2st1
uniprot id: G1K9R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane

28377:adgra3
gene id: 28377:adgra3
uniprot id: G1K980
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

28377:gnpda1
gene id: 28377:gnpda1
uniprot id: G1KNQ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

28377:c2
gene id: 28377:c2
uniprot id: A0A803TNT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Snake venom subfamily.
messages: Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:ptrf
gene id: 28377:ptrf
uniprot id: G1KUJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

28377:tmem87a
gene id: 28377:tmem87a
uniprot id: A0A803T2L9
uniprot id: G1KQY9
names: Subcellular Location Annotation
messages: Membrane

28377:thnsl1
gene id: 28377:thnsl1
uniprot id: G1KHW5
names: Similarity
messages: Belongs to the threonine synthase family.

28377:exo1
gene id: 28377:exo1
uniprot id: G1KBV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

28377:snx25
gene id: 28377:snx25
uniprot id: G1KAI8
names: Similarity
messages: Belongs to the sorting nexin family.

28377:mpeg1
gene id: 28377:mpeg1
uniprot id: G1KFN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPEG1 family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

28377:sprtn
gene id: 28377:sprtn
uniprot id: G1KB79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spartan family.
messages: Chromosome
messages: Nucleus

28377:tiparp
gene id: 28377:tiparp
uniprot id: G1K9I0
names: Similarity
messages: Belongs to the ARTD/PARP family.

28377:grem2
gene id: 28377:grem2
uniprot id: A0A803SVP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

28377:zdhhc22
gene id: 28377:zdhhc22
uniprot id: R4GBC6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

28377:slco4a1
gene id: 28377:slco4a1
uniprot id: G1KDM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

28377:eef1akmt1
gene id: 28377:eef1akmt1
uniprot id: A0A803SRA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

28377:rbp2
gene id: 28377:rbp2
uniprot id: G1KBY5
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

28377:tgfb1
gene id: 28377:tgfb1
uniprot id: H9GR44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
messages: extracellular matrix

28377:rbm48
gene id: 28377:rbm48
uniprot id: G1KR14
names: Similarity
messages: Belongs to the RBM48 family.

28377:psmc2
gene id: 28377:psmc2
uniprot id: G1KFN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

28377:asf1a
gene id: 28377:asf1a
uniprot id: G1KUA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

28377:fam150b
gene id: 28377:fam150b
uniprot id: G1KE11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

28377:cenpq
gene id: 28377:cenpq
uniprot id: R4GB65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-Q/OKP1 family.
messages: Nucleus

28377:dhcr7
gene id: 28377:dhcr7
uniprot id: A0A803TYD6
uniprot id: G1KRP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

28377:LOC100555992
gene id: 28377:LOC100555992
uniprot id: G1KA45
names: Similarity
messages: Belongs to the amidase family.

28377:tmem80
gene id: 28377:tmem80
uniprot id: G1KQQ5
names: Subcellular Location Annotation
messages: Membrane

28377:LOC100564642
gene id: 28377:LOC100564642
uniprot id: G1KY82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

28377:LOC100556126
gene id: 28377:LOC100556126
uniprot id: G1KD14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

28377:pcnx2
gene id: 28377:pcnx2
uniprot id: G1K8X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

28377:ppm1l
gene id: 28377:ppm1l
uniprot id: G1KXV5
names: Similarity
messages: Belongs to the PP2C family.

28377:LOC100554738
gene id: 28377:LOC100554738
uniprot id: G1KJN3
names: Similarity
messages: Belongs to the transferrin family.

28377:ptar1
gene id: 28377:ptar1
uniprot id: G1KVH4
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

28377:tulp4
gene id: 28377:tulp4
uniprot id: R4GA07
names: Similarity
messages: Belongs to the TUB family.

28377:bfsp1
gene id: 28377:bfsp1
uniprot id: G1KXK6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cell cortex
messages: cytoskeleton

28377:LOC100562614
gene id: 28377:LOC100562614
uniprot id: G1KE01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

28377:tspan7
gene id: 28377:tspan7
uniprot id: G1KQ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

28377:LOC100552382
gene id: 28377:LOC100552382
uniprot id: G1KPD5
names: Similarity
messages: Belongs to the cytochrome P450 family.

28377:bet1l
gene id: 28377:bet1l
uniprot id: A0A803T2V1
names: Subcellular Location Annotation
messages: Membrane

28377:kdelc1
gene id: 28377:kdelc1
uniprot id: G1KBB5
names: Similarity
messages: Belongs to the KDELC family.

28377:tjap1
gene id: 28377:tjap1
uniprot id: G1KJ48
names: Subcellular Location Annotation
messages: Membrane

28377:optn
gene id: 28377:optn
uniprot id: G1K9C2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Endosome
messages: Golgi apparatus
messages: May act by regulating membrane trafficking and cellular morphogenesis.
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: perinuclear region
messages: trans-Golgi network

28377:tiprl
gene id: 28377:tiprl
uniprot id: G1KKH2
names: Similarity
messages: Belongs to the TIP41 family.

28377:atp6v1c1
gene id: 28377:atp6v1c1
uniprot id: G1KIS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

28377:rplp2
gene id: 28377:rplp2
uniprot id: A0A803TD03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Heterodimer with RPLP1 at the lateral ribosomal stalk of the large ribosomal subunit.
messages: Plays an important role in the elongation step of protein synthesis.

28377:LOC100552705
gene id: 28377:LOC100552705
uniprot id: A0A803SPN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola
messages: sarcolemma

28377:LOC100559118
gene id: 28377:LOC100559118
uniprot id: A0A803SM81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

28377:ddx41
gene id: 28377:ddx41
uniprot id: G1KES9
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX41 subfamily.

28377:ptgis
gene id: 28377:ptgis
uniprot id: G1KRR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

28377:ccser1
gene id: 28377:ccser1
uniprot id: A0A803SVU2
uniprot id: G1KWX5
names: Similarity
messages: Belongs to the CCSER family.

28377:LOC100564569
gene id: 28377:LOC100564569
uniprot id: L7MZU4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28377:zdhhc13
gene id: 28377:zdhhc13
uniprot id: R4G950
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

28377:kif5b
gene id: 28377:kif5b
uniprot id: G1KGA8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

28377:rag2
gene id: 28377:rag2
uniprot id: G1KDJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAG2 family.
messages: Nucleus

28377:cacybp
gene id: 28377:cacybp
uniprot id: G1KQM7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
messages: Nucleus

28377:dct
gene id: 28377:dct
uniprot id: G1KB12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

28377:mcm8
gene id: 28377:mcm8
uniprot id: G1K8S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

28377:mfsd10
gene id: 28377:mfsd10
uniprot id: G1KVQ2
names: Subcellular Location Annotation
messages: Membrane

28377:tmem27
gene id: 28377:tmem27
uniprot id: G1KTF4
names: Subcellular Location Annotation
messages: Membrane

28377:arl4c
gene id: 28377:arl4c
uniprot id: G1KJP0
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

28377:ovol2
gene id: 28377:ovol2
uniprot id: G1KPM6
names: Subcellular Location Annotation
messages: Nucleus

28377:abhd12
gene id: 28377:abhd12
uniprot id: G1KPN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serine esterase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:tmem98
gene id: 28377:tmem98
uniprot id: A0A803T427
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM98 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: extracellular exosome

28377:rbx1
gene id: 28377:rbx1
uniprot id: G1KDQ9
names: Similarity
messages: Belongs to the RING-box family.

28377:tmem165
gene id: 28377:tmem165
uniprot id: G1KJ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

28377:hsf2
gene id: 28377:hsf2
uniprot id: G1K9B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

28377:msantd3
gene id: 28377:msantd3
uniprot id: G1KYI8
names: Similarity
messages: Belongs to the MSANTD3 family.

28377:capza2
gene id: 28377:capza2
uniprot id: G1KHL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

28377:npffr1
gene id: 28377:npffr1
uniprot id: G1KQU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

28377:orc5
gene id: 28377:orc5
uniprot id: G1KFY6
names: Subcellular Location Annotation
messages: Nucleus

28377:bora
gene id: 28377:bora
uniprot id: G1K8L4
names: Similarity
messages: Belongs to the BORA family.

28377:murc
gene id: 28377:murc
uniprot id: A0A803T1S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola
messages: sarcomere

28377:LOC107982405
gene id: 28377:LOC107982405
uniprot id: A0A803T5X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistin/FIZZ family.
messages: Secreted

28377:mkrn2
gene id: 28377:mkrn2
uniprot id: G1KNL1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

28377:gls2
gene id: 28377:gls2
uniprot id: G1KSU1
names: Similarity
messages: Belongs to the glutaminase family.

28377:ppard
gene id: 28377:ppard
uniprot id: G1KAH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

28377:crygs
gene id: 28377:crygs
uniprot id: G1KIH1
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

28377:pex16
gene id: 28377:pex16
uniprot id: G1KQE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Peroxisome membrane

28377:rpl24
gene id: 28377:rpl24
uniprot id: G1KLR6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

28377:spata6l
gene id: 28377:spata6l
uniprot id: A0A803TNY4
uniprot id: R4GC64
names: Similarity
messages: Belongs to the SPATA6 family.

28377:pdk4
gene id: 28377:pdk4
uniprot id: G1KPJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

28377:slco5a1
gene id: 28377:slco5a1
uniprot id: G1KQU4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:gabpa
gene id: 28377:gabpa
uniprot id: G1KQE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

28377:pcca
gene id: 28377:pcca
uniprot id: G1KC45
names: Subcellular Location Annotation
messages: Mitochondrion matrix

28377:yae1d1
gene id: 28377:yae1d1
uniprot id: A0A803SKX8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

28377:pkn2
gene id: 28377:pkn2
uniprot id: G1K9M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Midbody
messages: Nucleus

28377:s100z
gene id: 28377:s100z
uniprot id: A0A803TXS3
names: Similarity
messages: Belongs to the S-100 family.

28377:agpat3
gene id: 28377:agpat3
uniprot id: G1KUF3
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

28377:tmem255b
gene id: 28377:tmem255b
uniprot id: G1K8H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

28377:adhfe1
gene id: 28377:adhfe1
uniprot id: G1KSW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

28377:LOC100554046
gene id: 28377:LOC100554046
uniprot id: R4G9Y4
names: Similarity
messages: Belongs to the intermediate filament family.

28377:gtf2f1
gene id: 28377:gtf2f1
uniprot id: G1KR81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

28377:mms22l
gene id: 28377:mms22l
uniprot id: G1KK93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MMS22 family. MMS22L subfamily.
messages: Chromosome
messages: Nucleus

28377:LOC100566358
gene id: 28377:LOC100566358
uniprot id: G1KUE6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

28377:LOC100563415
gene id: 28377:LOC100563415
uniprot id: H9GUC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

28377:kcns2
gene id: 28377:kcns2
uniprot id: G1KS67
names: Subcellular Location Annotation
messages: Membrane

28377:ldah
gene id: 28377:ldah
uniprot id: G1KKE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

28377:ccdc67
gene id: 28377:ccdc67
uniprot id: G1KQC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP63 family.
messages: Cytoplasm

28377:LOC100562425
gene id: 28377:LOC100562425
uniprot id: G1KM52
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

28377:dzip1l
gene id: 28377:dzip1l
uniprot id: G1KIM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DZIP C2H2-type zinc-finger protein family.
messages: centriole
messages: cilium basal body

28377:ftcd
gene id: 28377:ftcd
uniprot id: G1KD94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds and promotes bundling of vimentin filaments originating from the Golgi.
messages: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.
messages: Golgi apparatus
messages: Homooctamer, including four polyglutamate binding sites. The subunits are arranged as a tetramer of dimers, and form a planar ring-shaped structure.
messages: In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family.
messages: In the N-terminal section; belongs to the formiminotransferase family.
messages: centriole

28377:tatdn3
gene id: 28377:tatdn3
uniprot id: G1KF93
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

28377:tcte3
gene id: 28377:tcte3
uniprot id: G1KB55
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

28377:parp3
gene id: 28377:parp3
uniprot id: G1KLC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

28377:mcu
gene id: 28377:mcu
uniprot id: G1K8V1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

28377:ren
gene id: 28377:ren
uniprot id: G1KH55
names: Similarity
messages: Belongs to the peptidase A1 family.

28377:rbfox2
gene id: 28377:rbfox2
uniprot id: A0A803T119
uniprot id: A0A803TEN8
uniprot id: G1KSS4
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

28377:mcur1
gene id: 28377:mcur1
uniprot id: G1KC38
names: Similarity
messages: Belongs to the CCDC90 family.

28377:rpl8
gene id: 28377:rpl8
uniprot id: G1KUJ6
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

28377:dnm2
gene id: 28377:dnm2
uniprot id: A0A803SQT7
uniprot id: A0A803SST4
uniprot id: G1KR95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: cytoskeleton

28377:LOC100558338
gene id: 28377:LOC100558338
uniprot id: A0A803TH21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

28377:myo3a
gene id: 28377:myo3a
uniprot id: G1KHV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: In the C-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

28377:recql5
gene id: 28377:recql5
uniprot id: G1KFY1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

28377:btf3
gene id: 28377:btf3
uniprot id: A0A803TIH9
names: Similarity
messages: Belongs to the NAC-beta family.

28377:dpysl3
gene id: 28377:dpysl3
uniprot id: A0A803TY90
uniprot id: G1KQA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Cytoplasm
messages: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
messages: growth cone

28377:dpy30
gene id: 28377:dpy30
uniprot id: G1K8Q1
names: Similarity
messages: Belongs to the dpy-30 family.

28377:atg2b
gene id: 28377:atg2b
uniprot id: G1KNQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

28377:prss12
gene id: 28377:prss12
uniprot id: G1KP66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Snake venom subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.
messages: Secreted

28377:ND2
gene id: 28377:ND2
uniprot id: B3GSZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 2 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

28377:idnk
gene id: 28377:idnk
uniprot id: G1KA38
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

28377:kcnk13
gene id: 28377:kcnk13
uniprot id: A0A803TQP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

28377:abhd3
gene id: 28377:abhd3
uniprot id: G1KH59
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

28377:slc16a5
gene id: 28377:slc16a5
uniprot id: G1KF31
names: Subcellular Location Annotation
messages: Membrane

28377:akt2
gene id: 28377:akt2
uniprot id: H9G6X3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

28377:il2rb
gene id: 28377:il2rb
uniprot id: A0A803T4P8
uniprot id: A0A803TD52
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Cell membrane
messages: Membrane
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Interacts with SHB upon interleukin stimulation.

28377:aff4
gene id: 28377:aff4
uniprot id: G1KV91
names: Similarity
messages: Belongs to the AF4 family.

28377:fbln5
gene id: 28377:fbln5
uniprot id: G1KIX9
names: Caution
names: Similarity
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:fam134c
gene id: 28377:fam134c
uniprot id: G1KP55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Membrane

28377:atp6v0b
gene id: 28377:atp6v0b
uniprot id: G1KPU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: clathrin-coated vesicle membrane

28377:hspa4l
gene id: 28377:hspa4l
uniprot id: G1KLL7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

28377:tmem41b
gene id: 28377:tmem41b
uniprot id: G1KJ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

28377:tppp
gene id: 28377:tppp
uniprot id: G1KIV9
names: Similarity
messages: Belongs to the TPPP family.

28377:arrdc3
gene id: 28377:arrdc3
uniprot id: G1KNQ9
names: Similarity
messages: Belongs to the arrestin family.

28377:mapk9
gene id: 28377:mapk9
uniprot id: A0A803TPY9
uniprot id: A0A803U046
uniprot id: G1KSZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

28377:ntf3
gene id: 28377:ntf3
uniprot id: A0A803TRM2
uniprot id: G1KIN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted
messages: Seems to promote the survival of visceral and proprioceptive sensory neurons.

28377:asun
gene id: 28377:asun
uniprot id: A0A803SSA3
uniprot id: G1KLZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the asunder family.
messages: Cytoplasm
messages: Nucleus

28377:scn3b
gene id: 28377:scn3b
uniprot id: H9G9H8
names: Subcellular Location Annotation
messages: Membrane

28377:nsmce2
gene id: 28377:nsmce2
uniprot id: G1KJZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

28377:fam160a1
gene id: 28377:fam160a1
uniprot id: G1KBB6
names: Similarity
messages: Belongs to the FHIP family.

28377:chrna4
gene id: 28377:chrna4
uniprot id: G1KER0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

28377:emc10
gene id: 28377:emc10
uniprot id: G1KM47
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC10 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

28377:slc7a13
gene id: 28377:slc7a13
uniprot id: G1KPC5
names: Subcellular Location Annotation
messages: Membrane

28377:me3
gene id: 28377:me3
uniprot id: G1KB19
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

28377:stmn2
gene id: 28377:stmn2
uniprot id: G1KNP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the stathmin family.
messages: Cytoplasm
messages: Membrane
messages: lamellipodium

28377:cntnap5
gene id: 28377:cntnap5
uniprot id: G1KFB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.
messages: Membrane

28377:gpr25
gene id: 28377:gpr25
uniprot id: G1KJP2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:LOC100566109
gene id: 28377:LOC100566109
uniprot id: A0A803TC62
uniprot id: A0A803TSF1
uniprot id: G1KJ19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

28377:LOC100557683
gene id: 28377:LOC100557683
uniprot id: A0A803SPS6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

28377:LOC100564769
gene id: 28377:LOC100564769
uniprot id: G1KMX1
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

28377:actr6
gene id: 28377:actr6
uniprot id: G1KMN2
names: Similarity
messages: Belongs to the actin family. ARP6 subfamily.

28377:tmem45a
gene id: 28377:tmem45a
uniprot id: G1KL80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

28377:wnt8a
gene id: 28377:wnt8a
uniprot id: G1KTD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

28377:grin3a
gene id: 28377:grin3a
uniprot id: G1KKS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

28377:snx9
gene id: 28377:snx9
uniprot id: A0A803ST54
uniprot id: G1KDL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

28377:LOC100564964
gene id: 28377:LOC100564964
uniprot id: G1KN22
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

28377:adgre5
gene id: 28377:adgre5
uniprot id: A0A803T6T4
uniprot id: A0A803TKJ7
uniprot id: G1KKJ9
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:ago2
gene id: 28377:ago2
uniprot id: G1K8D5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family. Ago subfamily.
messages: Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of dicer1, ago2 and tarbp2. Note that the trimeric RLC/miRLC is also referred to as RISC.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by ago2. Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity. The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur.
messages: The Piwi domain may perform RNA cleavage by a mechanism similar to that of RNase H. However, while RNase H utilizes a triad of Asp-Asp-Glu (DDE) for metal ion coordination, this protein appears to utilize a triad of Asp-Asp-His (DDH).

28377:LOC100558140
gene id: 28377:LOC100558140
uniprot id: G1KJG0
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

28377:pkp3
gene id: 28377:pkp3
uniprot id: G1KNU2
names: Similarity
messages: Belongs to the beta-catenin family.

28377:cfap206
gene id: 28377:cfap206
uniprot id: G1KQR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP206 family.
messages: cilium axoneme
messages: cilium basal body

28377:acss1
gene id: 28377:acss1
uniprot id: G1KP87
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

28377:mrpl43
gene id: 28377:mrpl43
uniprot id: A0A803TAI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

28377:ndnf
gene id: 28377:ndnf
uniprot id: G1KN23
names: Subcellular Location Annotation
messages: Secreted

28377:rell2
gene id: 28377:rell2
uniprot id: A0A803TH65
uniprot id: G1KLH2
names: Similarity
messages: Belongs to the RELT family.

28377:gja5
gene id: 28377:gja5
uniprot id: G1KPB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

28377:LOC100564904
gene id: 28377:LOC100564904
uniprot id: G1KL93
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

28377:atp11a
gene id: 28377:atp11a
uniprot id: A0A803ST26
uniprot id: G1KFM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

28377:cdc6
gene id: 28377:cdc6
uniprot id: G1KAT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
messages: Nucleus

28377:enkur
gene id: 28377:enkur
uniprot id: G1KHX8
names: Subcellular Location Annotation
messages: cilium axoneme

28377:mki67
gene id: 28377:mki67
uniprot id: A0A803TS10
names: Subcellular Location Annotation
messages: Nucleus

28377:tmem39a
gene id: 28377:tmem39a
uniprot id: G1KUA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

28377:senp6
gene id: 28377:senp6
uniprot id: A0A803T835
uniprot id: A0A803TA42
uniprot id: G1KDF3
names: Similarity
messages: Belongs to the peptidase C48 family.

28377:gpr17
gene id: 28377:gpr17
uniprot id: G1KE19
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:rpl37
gene id: 28377:rpl37
uniprot id: A0A803TIH1
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

28377:LOC100567205
gene id: 28377:LOC100567205
uniprot id: H9GFJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

28377:tmeff1
gene id: 28377:tmeff1
uniprot id: G1K9W6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:LOC100552897
gene id: 28377:LOC100552897
uniprot id: A0A803TZE7
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

28377:hyal1
gene id: 28377:hyal1
uniprot id: G1KX26
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Monomer.

28377:ipo8
gene id: 28377:ipo8
uniprot id: A0A803SX82
uniprot id: G1KN53
names: Subcellular Location Annotation
messages: Cytoplasm

28377:p2rx4
gene id: 28377:p2rx4
uniprot id: H9GN73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

28377:snx13
gene id: 28377:snx13
uniprot id: G1KM72
names: Similarity
messages: Belongs to the sorting nexin family.

28377:LOC100564437
gene id: 28377:LOC100564437
uniprot id: G1KEQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

28377:adgrg6
gene id: 28377:adgrg6
uniprot id: A0A803TQD1
uniprot id: G1KHR0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:dpt
gene id: 28377:dpt
uniprot id: G1KKE7
names: Similarity
messages: Belongs to the dermatopontin family.

28377:gtpbp4
gene id: 28377:gtpbp4
uniprot id: G1KBJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

28377:sdc1
gene id: 28377:sdc1
uniprot id: G1KK50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane
messages: extracellular exosome

28377:mtf2
gene id: 28377:mtf2
uniprot id: A0A803TIJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

28377:tsen2
gene id: 28377:tsen2
uniprot id: G1KNL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

28377:abcc3
gene id: 28377:abcc3
uniprot id: G1K9J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

28377:LOC103277727
gene id: 28377:LOC103277727
uniprot id: G1KR96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

28377:tfb1m
gene id: 28377:tfb1m
uniprot id: A0A803SRT3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

28377:sptlc2
gene id: 28377:sptlc2
uniprot id: G1KTP4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

28377:mterf2
gene id: 28377:mterf2
uniprot id: G1KQX1
names: Similarity
messages: Belongs to the mTERF family.

28377:lamb1
gene id: 28377:lamb1
uniprot id: G1KCX1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

28377:gtf2h5
gene id: 28377:gtf2h5
uniprot id: A0A803T9V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

28377:eef1a2
gene id: 28377:eef1a2
uniprot id: G1KEW8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

28377:vrk1
gene id: 28377:vrk1
uniprot id: G1KP35
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:nop14
gene id: 28377:nop14
uniprot id: G1KDZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

28377:sema3e
gene id: 28377:sema3e
uniprot id: A0A803SM90
uniprot id: G1KSB1
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:nkx2-2
gene id: 28377:nkx2-2
uniprot id: G1KEI4
names: Subcellular Location Annotation
messages: Nucleus

28377:tmem167b
gene id: 28377:tmem167b
uniprot id: G1KJQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

28377:LOC100556776
gene id: 28377:LOC100556776
uniprot id: L7MZH4
names: Similarity
messages: Belongs to the CLCR family.

28377:myf6
gene id: 28377:myf6
uniprot id: A0A803TTJ0
names: Subcellular Location Annotation
messages: Nucleus

28377:rimklb
gene id: 28377:rimklb
uniprot id: G1KTW5
names: Similarity
messages: Belongs to the RimK family.

28377:ube2f
gene id: 28377:ube2f
uniprot id: A0A803U131
uniprot id: G1KRU9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

28377:slc25a4
gene id: 28377:slc25a4
uniprot id: G1KAL3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

28377:dis3
gene id: 28377:dis3
uniprot id: A0A803SWG8
names: Similarity
messages: Belongs to the RNR ribonuclease family.

28377:nfya
gene id: 28377:nfya
uniprot id: A0A803SVQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

28377:LOC100560379
gene id: 28377:LOC100560379
uniprot id: A0A803TEX0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

28377:ogn
gene id: 28377:ogn
uniprot id: G1KIK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
messages: Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
messages: extracellular matrix

28377:esrrg
gene id: 28377:esrrg
uniprot id: A0A803T607
uniprot id: A0A803TAH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

28377:nek3
gene id: 28377:nek3
uniprot id: G1KT47
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:sim2
gene id: 28377:sim2
uniprot id: G1KYD3
names: Subcellular Location Annotation
messages: Nucleus

28377:tusc3
gene id: 28377:tusc3
uniprot id: A0A803TTU8
uniprot id: A0A803U186
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:nr1h3
gene id: 28377:nr1h3
uniprot id: G1KBE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

28377:plppr5
gene id: 28377:plppr5
uniprot id: A0A803SQD6
uniprot id: R4GDG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

28377:tspan18
gene id: 28377:tspan18
uniprot id: G1KPX8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:mcm2
gene id: 28377:mcm2
uniprot id: G1KGN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

28377:g6pd
gene id: 28377:g6pd
uniprot id: G1KMH2
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.

28377:LOC103278483
gene id: 28377:LOC103278483
uniprot id: G1KUR9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:LOC100562879
gene id: 28377:LOC100562879
uniprot id: A0A803TXV5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

28377:parp8
gene id: 28377:parp8
uniprot id: G1KCX2
names: Similarity
messages: Belongs to the ARTD/PARP family.

28377:cpa6
gene id: 28377:cpa6
uniprot id: G1KSF0
names: Similarity
messages: Belongs to the peptidase M14 family.

28377:ocln
gene id: 28377:ocln
uniprot id: G1KWJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

28377:arhgef3
gene id: 28377:arhgef3
uniprot id: A0A803TZP1
names: Function
names: Subcellular Location Annotation
messages: Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
messages: Cytoplasm

28377:ghrhr
gene id: 28377:ghrhr
uniprot id: A0A803TI46
uniprot id: A0A803TRI7
names: Subcellular Location Annotation
messages: Membrane

28377:galnt1
gene id: 28377:galnt1
uniprot id: G1KFW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

28377:lias
gene id: 28377:lias
uniprot id: G1KGD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

28377:gatad1
gene id: 28377:gatad1
uniprot id: A0A803TAW1
uniprot id: G1KR66
names: Subcellular Location Annotation
messages: Nucleus

28377:casc3
gene id: 28377:casc3
uniprot id: A0A803TXR6
uniprot id: G1KB37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASC3 family.
messages: Nucleus speckle
messages: dendrite
messages: perinuclear region

28377:prkab2
gene id: 28377:prkab2
uniprot id: G1KNE5
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

28377:prss35
gene id: 28377:prss35
uniprot id: G1KCP3
names: Similarity
messages: Belongs to the peptidase S1 family. Snake venom subfamily.

28377:aplnr
gene id: 28377:aplnr
uniprot id: L7MZR0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:ergic2
gene id: 28377:ergic2
uniprot id: G1KHL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

28377:snrpe
gene id: 28377:snrpe
uniprot id: G1KJN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

28377:LOC100560626
gene id: 28377:LOC100560626
uniprot id: G1KMQ2
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.

28377:epha4
gene id: 28377:epha4
uniprot id: G1KDW5
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome
messages: Membrane

28377:pitrm1
gene id: 28377:pitrm1
uniprot id: G1KHM5
names: Subunit
messages: Monomer and homodimer; homodimerization is induced by binding of the substrate.

28377:LOC100555543
gene id: 28377:LOC100555543
uniprot id: H9GNI2
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

28377:ctnnbip1
gene id: 28377:ctnnbip1
uniprot id: A0A803TVA7
names: Similarity
messages: Belongs to the CTNNBIP1 family.

28377:nos1
gene id: 28377:nos1
uniprot id: H9GND1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOS family.
messages: dendritic spine
messages: sarcolemma

28377:notum
gene id: 28377:notum
uniprot id: G1KJY3
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

28377:tsn
gene id: 28377:tsn
uniprot id: A0A803TAL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the translin family.
messages: DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.
messages: Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
messages: Nucleus
messages: Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring.

28377:degs1
gene id: 28377:degs1
uniprot id: G1KE41
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Interacts with RLBP1; the interaction increases synthesis of chromophore-precursors by DEGS1.
messages: Membrane

28377:prkci
gene id: 28377:prkci
uniprot id: G1KRY6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

28377:ptpn4
gene id: 28377:ptpn4
uniprot id: G1KUQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

28377:prss16
gene id: 28377:prss16
uniprot id: H9GHB0
names: Similarity
messages: Belongs to the peptidase S28 family.

28377:sept3
gene id: 28377:sept3
uniprot id: A0A803THZ0
uniprot id: G1KCI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cytoplasm

28377:LOC100557361
gene id: 28377:LOC100557361
uniprot id: G1KW35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

28377:tmem131
gene id: 28377:tmem131
uniprot id: G1KM90
names: Similarity
messages: Belongs to the TMEM131 family.

28377:LOC100564897
gene id: 28377:LOC100564897
uniprot id: L7MZY8
uniprot id: L7MZZ1
names: Similarity
messages: Belongs to the cytochrome P450 family.

28377:atp5f1
gene id: 28377:atp5f1
uniprot id: A0A803STE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

28377:zdhhc2
gene id: 28377:zdhhc2
uniprot id: G1KF61
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

28377:vsx2
gene id: 28377:vsx2
uniprot id: G1KSG9
names: Subcellular Location Annotation
messages: Nucleus

28377:usp15
gene id: 28377:usp15
uniprot id: A0A803TDV1
uniprot id: G1K9E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Nucleus

28377:atp10a
gene id: 28377:atp10a
uniprot id: G1KLR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

28377:arsb
gene id: 28377:arsb
uniprot id: G1KT81
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

28377:mpped1
gene id: 28377:mpped1
uniprot id: A0A803SMV2
names: Similarity
messages: Belongs to the UPF0046 family.

28377:LOC100562210
gene id: 28377:LOC100562210
uniprot id: A0A803TMD4
names: Similarity
messages: Belongs to the NDK family.

28377:sv2c
gene id: 28377:sv2c
uniprot id: G1KHP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

28377:gng4
gene id: 28377:gng4
uniprot id: G1K9Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

28377:bbs7
gene id: 28377:bbs7
uniprot id: G1KMJ2
names: Function
names: Subunit
messages: Part of BBSome complex.
messages: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.

28377:lig4
gene id: 28377:lig4
uniprot id: G1KPZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

28377:gcnt4
gene id: 28377:gcnt4
uniprot id: G1KIA8
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

28377:kiz
gene id: 28377:kiz
uniprot id: R4GBP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kizuna family.
messages: Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.
messages: centrosome
messages: cilium basal body

28377:gda
gene id: 28377:gda
uniprot id: G1KMU1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

28377:LOC100564704
gene id: 28377:LOC100564704
uniprot id: G1KB50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

28377:slitrk5
gene id: 28377:slitrk5
uniprot id: G1KJF8
names: Similarity
messages: Belongs to the SLITRK family.

28377:fshr
gene id: 28377:fshr
uniprot id: G1KSH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
messages: Membrane

28377:tmem63c
gene id: 28377:tmem63c
uniprot id: R4GD55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

28377:msh6
gene id: 28377:msh6
uniprot id: G1KPH8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

28377:nap1l4
gene id: 28377:nap1l4
uniprot id: G1K899
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

28377:kcnn4
gene id: 28377:kcnn4
uniprot id: H9G9A0
names: Subcellular Location Annotation
messages: Membrane

28377:cacnb2
gene id: 28377:cacnb2
uniprot id: A0A803SZ96
uniprot id: G1KEE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
messages: sarcolemma

28377:rps27a
gene id: 28377:rps27a
uniprot id: G1KBR8
names: Similarity
names: Subunit
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Ribosomal protein S27a is part of the 40S ribosomal subunit.

28377:bcap29
gene id: 28377:bcap29
uniprot id: G1KQS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

28377:pnpo
gene id: 28377:pnpo
uniprot id: G1KFQ7
names: Function
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

28377:ostc
gene id: 28377:ostc
uniprot id: G1KMF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OSTC family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

28377:fh
gene id: 28377:fh
uniprot id: G1KJB7
names: Function
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH.

28377:odf1
gene id: 28377:odf1
uniprot id: G1KII8
names: Function
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.

28377:thnsl2
gene id: 28377:thnsl2
uniprot id: G1KHS9
names: Similarity
messages: Belongs to the threonine synthase family.

28377:fam161b
gene id: 28377:fam161b
uniprot id: A0A803SU21
uniprot id: G1KS76
names: Similarity
messages: Belongs to the FAM161 family.

28377:snw1
gene id: 28377:snw1
uniprot id: G1KTQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNW family.
messages: Identified in the spliceosome C complex.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

28377:prss23
gene id: 28377:prss23
uniprot id: G1KB22
names: Similarity
messages: Belongs to the peptidase S1 family. Snake venom subfamily.

28377:manf
gene id: 28377:manf
uniprot id: G1KGX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

28377:med14
gene id: 28377:med14
uniprot id: A0A803TCF6
uniprot id: G1KPT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

28377:krr1
gene id: 28377:krr1
uniprot id: G1KH40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

28377:mbtps2
gene id: 28377:mbtps2
uniprot id: G1KT01
names: Similarity
messages: Belongs to the peptidase M50A family.

28377:fam171a2
gene id: 28377:fam171a2
uniprot id: G1KM06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

28377:amer3
gene id: 28377:amer3
uniprot id: G1KD76
names: Similarity
messages: Belongs to the Amer family.

28377:trappc3l
gene id: 28377:trappc3l
uniprot id: A0A803U079
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

28377:march11
gene id: 28377:march11
uniprot id: G1K8F0
names: Subcellular Location Annotation
messages: Membrane

28377:cct5
gene id: 28377:cct5
uniprot id: G1KK81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

28377:hs3st5
gene id: 28377:hs3st5
uniprot id: G1KM36
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

28377:LOC100557302
gene id: 28377:LOC100557302
uniprot id: G1KCB5
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

28377:otop2
gene id: 28377:otop2
uniprot id: G1KER1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

28377:ppp1r9a
gene id: 28377:ppp1r9a
uniprot id: G1KVZ2
names: Subcellular Location Annotation
messages: cytoskeleton

28377:LOC103279059
gene id: 28377:LOC103279059
uniprot id: A0A803TBM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

28377:apob
gene id: 28377:apob
uniprot id: G1KKJ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:aco2
gene id: 28377:aco2
uniprot id: G1KD44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Mitochondrion

28377:LOC100563983
gene id: 28377:LOC100563983
uniprot id: G1KI33
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Monomer.

28377:ggact
gene id: 28377:ggact
uniprot id: G1KBZ7
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine.

28377:txlng
gene id: 28377:txlng
uniprot id: G1KL89
names: Similarity
messages: Belongs to the taxilin family.

28377:slc7a1
gene id: 28377:slc7a1
uniprot id: G1KCP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

28377:rpl30
gene id: 28377:rpl30
uniprot id: G1KS11
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

28377:ppp2r5d
gene id: 28377:ppp2r5d
uniprot id: G1KE39
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

28377:fam221a
gene id: 28377:fam221a
uniprot id: G1KNU4
names: Similarity
messages: Belongs to the FAM221 family.

28377:LOC100560217
gene id: 28377:LOC100560217
uniprot id: G1KWY8
names: Similarity
messages: Belongs to the serpin family.

28377:LOC100566793
gene id: 28377:LOC100566793
uniprot id: R4GBP5
names: Subcellular Location Annotation
messages: Secreted

28377:mpped2
gene id: 28377:mpped2
uniprot id: G1KW46
names: Similarity
messages: Belongs to the UPF0046 family.

28377:LOC100554951
gene id: 28377:LOC100554951
uniprot id: G1KNM9
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

28377:fshb
gene id: 28377:fshb
uniprot id: G1KA28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

28377:ckap2
gene id: 28377:ckap2
uniprot id: G1KT45
names: Similarity
messages: Belongs to the CKAP2 family.

28377:LOC100564587
gene id: 28377:LOC100564587
uniprot id: G1KX70
names: Similarity
messages: Belongs to the aldo/keto reductase family.

28377:mrpl2
gene id: 28377:mrpl2
uniprot id: G1KDM8
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

28377:uroc1
gene id: 28377:uroc1
uniprot id: G1KP64
names: Similarity
messages: Belongs to the urocanase family.

28377:npy2r
gene id: 28377:npy2r
uniprot id: G1KR99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:sybu
gene id: 28377:sybu
uniprot id: A0A803SXI6
names: Subcellular Location Annotation
messages: Membrane

28377:cfap36
gene id: 28377:cfap36
uniprot id: G1KC16
names: Similarity
messages: Belongs to the CFAP36 family.

28377:st7l
gene id: 28377:st7l
uniprot id: G1KUJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

28377:psmg1
gene id: 28377:psmg1
uniprot id: G1K897
names: Similarity
messages: Belongs to the PSMG1 family.

28377:mterf3
gene id: 28377:mterf3
uniprot id: G1KCK0
names: Similarity
messages: Belongs to the mTERF family.

28377:LOC100556372
gene id: 28377:LOC100556372
uniprot id: G1KRJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sulfate transporter. May play a role in endochondral bone formation.

28377:sec24d
gene id: 28377:sec24d
uniprot id: G1KP05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

28377:fzd2
gene id: 28377:fzd2
uniprot id: G1KME9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:tbxas1
gene id: 28377:tbxas1
uniprot id: G1KTB2
names: Similarity
messages: Belongs to the cytochrome P450 family.

28377:foxm1
gene id: 28377:foxm1
uniprot id: A0A803T1D9
uniprot id: A0A803TP83
uniprot id: G1KQZ9
names: Subcellular Location Annotation
messages: Nucleus

28377:vgll4
gene id: 28377:vgll4
uniprot id: G1KJY4
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

28377:atg101
gene id: 28377:atg101
uniprot id: A0A803TH95
names: Similarity
messages: Belongs to the ATG101 family.

28377:senp7
gene id: 28377:senp7
uniprot id: G1KLK5
names: Similarity
messages: Belongs to the peptidase C48 family.

28377:ndc80
gene id: 28377:ndc80
uniprot id: G1KI76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

28377:qki
gene id: 28377:qki
uniprot id: G1KBR3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

28377:slitrk6
gene id: 28377:slitrk6
uniprot id: G1KCS9
names: Similarity
messages: Belongs to the SLITRK family.

28377:LOC100552242
gene id: 28377:LOC100552242
uniprot id: G1KB61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

28377:ndufb9
gene id: 28377:ndufb9
uniprot id: G1KJK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

28377:aqp4
gene id: 28377:aqp4
uniprot id: G1KAC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

28377:acp1
gene id: 28377:acp1
uniprot id: G1KE09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

28377:kdelc2
gene id: 28377:kdelc2
uniprot id: A0A803T7T2
uniprot id: G1KDW4
names: Similarity
messages: Belongs to the KDELC family.

28377:pfdn1
gene id: 28377:pfdn1
uniprot id: G1KNY0
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

28377:gps1
gene id: 28377:gps1
uniprot id: G1KJP1
uniprot id: R4G9Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN1 family.
messages: Cytoplasm
messages: Nucleus

28377:kcnab1
gene id: 28377:kcnab1
uniprot id: G1K9F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

28377:fam91a1
gene id: 28377:fam91a1
uniprot id: G1KJH3
names: Similarity
messages: Belongs to the FAM91 family.

28377:npvf
gene id: 28377:npvf
uniprot id: G1KN65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

28377:xylb
gene id: 28377:xylb
uniprot id: G1KM28
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.

28377:foxred2
gene id: 28377:foxred2
uniprot id: G1KSH7
names: Similarity
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.

28377:mgat5
gene id: 28377:mgat5
uniprot id: G1KAW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Secreted

28377:ptk7
gene id: 28377:ptk7
uniprot id: G1KDC3
names: Subcellular Location Annotation
messages: Membrane

28377:rp2
gene id: 28377:rp2
uniprot id: G1KLV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
messages: Belongs to the TBCC family.
messages: Cell membrane
messages: Membrane

28377:LOC100558542
gene id: 28377:LOC100558542
uniprot id: G1KU16
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:LOC100567919
gene id: 28377:LOC100567919
uniprot id: G1KMX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion membrane

28377:LOC100554616
gene id: 28377:LOC100554616
uniprot id: A0A803TQN6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

28377:eef2
gene id: 28377:eef2
uniprot id: G1KM79
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

28377:chchd4
gene id: 28377:chchd4
uniprot id: G1KP24
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

28377:impa1
gene id: 28377:impa1
uniprot id: G1KP58
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

28377:tmem136
gene id: 28377:tmem136
uniprot id: H9G7E2
names: Subcellular Location Annotation
messages: Membrane

28377:pik3cb
gene id: 28377:pik3cb
uniprot id: G1KBQ4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

28377:itfg1
gene id: 28377:itfg1
uniprot id: H9GKF2
names: Similarity
messages: Belongs to the TIP family.

28377:LOC100567055
gene id: 28377:LOC100567055
uniprot id: G1KHP6
names: Similarity
messages: Belongs to the intermediate filament family.

28377:fasn
gene id: 28377:fasn
uniprot id: G1KJG9
names: Function
messages: Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.

28377:mtus1
gene id: 28377:mtus1
uniprot id: A0A803SS71
uniprot id: A0A803T599
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTUS1 family.
messages: Nucleus

28377:arl8a
gene id: 28377:arl8a
uniprot id: G1KCL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

28377:pld4
gene id: 28377:pld4
uniprot id: G1KL33
names: Similarity
messages: Belongs to the phospholipase D family.

28377:c1h11orf58
gene id: 28377:c1h11orf58
uniprot id: G1K872
names: Similarity
messages: Belongs to the SMAP family.

28377:emc7
gene id: 28377:emc7
uniprot id: G1KR03
names: Similarity
names: Subunit
messages: Belongs to the EMC7 family.
messages: Component of the ER membrane protein complex (EMC).

28377:eif2a
gene id: 28377:eif2a
uniprot id: G1KGY6
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

28377:LOC100555013
gene id: 28377:LOC100555013
uniprot id: G1KM29
names: Similarity
messages: Belongs to the perilipin family.

28377:sec61g
gene id: 28377:sec61g
uniprot id: A0A803SRE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:gad2
gene id: 28377:gad2
uniprot id: G1KHN1
names: Similarity
messages: Belongs to the group II decarboxylase family.

28377:dlgap1
gene id: 28377:dlgap1
uniprot id: A0A803T2S8
uniprot id: A0A803TUV2
uniprot id: G1KZ33
names: Similarity
messages: Belongs to the SAPAP family.

28377:c3h2orf40
gene id: 28377:c3h2orf40
uniprot id: G1KK53
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the augurin family.
messages: Cytoplasm
messages: Membrane
messages: Secreted

28377:LOC100564371
gene id: 28377:LOC100564371
uniprot id: P41592
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. This opsin uses a vitamin A2 chromophore.

28377:tpd52
gene id: 28377:tpd52
uniprot id: A0A803SVF2
names: Similarity
messages: Belongs to the TPD52 family.

28377:max
gene id: 28377:max
uniprot id: A0A803SRT9
names: Similarity
messages: Belongs to the MAX family.

28377:ccdc107
gene id: 28377:ccdc107
uniprot id: R4G995
names: Similarity
messages: Belongs to the ric-3 family.

28377:mpp2
gene id: 28377:mpp2
uniprot id: G1KDF5
names: Similarity
messages: Belongs to the MAGUK family.

28377:sdhaf3
gene id: 28377:sdhaf3
uniprot id: A0A803TFZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

28377:LOC100556689
gene id: 28377:LOC100556689
uniprot id: G1KRB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

28377:smg9
gene id: 28377:smg9
uniprot id: H9G947
names: Similarity
messages: Belongs to the SMG9 family.

28377:pan3
gene id: 28377:pan3
uniprot id: G1KIR2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PABPC1 (via PABC domain), conferring substrate specificity of the enzyme complex. Interacts with the GW182 family proteins TNRC6A, TNRC6B and TNRC6C.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: P-body
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

28377:bcl2l13
gene id: 28377:bcl2l13
uniprot id: G1KME5
names: Similarity
messages: Belongs to the Bcl-2 family.

28377:LOC100559647
gene id: 28377:LOC100559647
uniprot id: R4GBC1
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Homotetramer.

28377:LOC100551746
gene id: 28377:LOC100551746
uniprot id: R4G936
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNF-like-inhibitor family.
messages: Secreted

28377:sod3
gene id: 28377:sod3
uniprot id: G1K8G8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

28377:adcy2
gene id: 28377:adcy2
uniprot id: G1KJT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

28377:dph6
gene id: 28377:dph6
uniprot id: A0A803TXM5
uniprot id: R4G926
names: Similarity
messages: Belongs to the Diphthine--ammonia ligase family.

28377:LOC100561305
gene id: 28377:LOC100561305
uniprot id: A0A803SY83
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28377:sesn1
gene id: 28377:sesn1
uniprot id: G1KF20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

28377:nt5dc2
gene id: 28377:nt5dc2
uniprot id: G1KG58
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

28377:ctnnd1
gene id: 28377:ctnnd1
uniprot id: A0A803TFZ4
uniprot id: G1KG06
names: Similarity
messages: Belongs to the beta-catenin family.

28377:dusp8
gene id: 28377:dusp8
uniprot id: R4GDI9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

28377:c2h17orf80
gene id: 28377:c2h17orf80
uniprot id: A0A803T0U7
names: Function
names: Similarity
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

28377:exoc8
gene id: 28377:exoc8
uniprot id: G1KB83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO84 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: growth cone
messages: perinuclear region

28377:khdrbs3
gene id: 28377:khdrbs3
uniprot id: G1KLV1
names: Similarity
messages: Belongs to the KHDRBS family.

28377:plppr2
gene id: 28377:plppr2
uniprot id: A0A803SMM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

28377:ypel4
gene id: 28377:ypel4
uniprot id: G1KG73
names: Similarity
messages: Belongs to the yippee family.

28377:LOC100562752
gene id: 28377:LOC100562752
uniprot id: G1KSL1
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

28377:hdac2
gene id: 28377:hdac2
uniprot id: G1KM32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
messages: Nucleus

28377:hacd4
gene id: 28377:hacd4
uniprot id: R4GA96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:btg1
gene id: 28377:btg1
uniprot id: A0A803TSG1
names: Function
names: Similarity
messages: Anti-proliferative protein.
messages: Belongs to the BTG family.

28377:tgfb2
gene id: 28377:tgfb2
uniprot id: G1K950
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

28377:smarca2
gene id: 28377:smarca2
uniprot id: G1KBB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

28377:g6pc3
gene id: 28377:g6pc3
uniprot id: G1KCY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

28377:c3h21orf59
gene id: 28377:c3h21orf59
uniprot id: G1KBD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP298 family.
messages: cilium basal body

28377:frem1
gene id: 28377:frem1
uniprot id: G1KUD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRAS1 family.
messages: Secreted

28377:gpt2
gene id: 28377:gpt2
uniprot id: H9GK05
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

28377:ldlr
gene id: 28377:ldlr
uniprot id: G1KSU0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:LOC100566807
gene id: 28377:LOC100566807
uniprot id: A0A803TR52
names: Similarity
messages: Belongs to the osteocalcin/matrix Gla protein family.

28377:rps19bp1
gene id: 28377:rps19bp1
uniprot id: G1KGR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AROS family.
messages: nucleolus

28377:synj2
gene id: 28377:synj2
uniprot id: G1KDF1
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

28377:epc1
gene id: 28377:epc1
uniprot id: G1KG32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

28377:atic
gene id: 28377:atic
uniprot id: G1KRC2
names: Similarity
messages: Belongs to the PurH family.

28377:inhba
gene id: 28377:inhba
uniprot id: G1KU54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

28377:LOC100561357
gene id: 28377:LOC100561357
uniprot id: G1KP45
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:LOC100563852
gene id: 28377:LOC100563852
uniprot id: G1KRH4
names: Similarity
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.

28377:agxt
gene id: 28377:agxt
uniprot id: G1KG79
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

28377:ip6k1
gene id: 28377:ip6k1
uniprot id: G1KGD5
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

28377:vegfc
gene id: 28377:vegfc
uniprot id: G1KEU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

28377:gli3
gene id: 28377:gli3
uniprot id: A0A803U1R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus

28377:LOC100562478
gene id: 28377:LOC100562478
uniprot id: R4GBZ0
names: Similarity
messages: Belongs to the tigger transposable element derived protein family.

28377:mrps7
gene id: 28377:mrps7
uniprot id: G1KFD7
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

28377:LOC100567925
gene id: 28377:LOC100567925
uniprot id: A0A803TSD2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

28377:cep170b
gene id: 28377:cep170b
uniprot id: A0A803T6W0
uniprot id: G1KL52
names: Similarity
messages: Belongs to the CEP170 family.

28377:kcna7
gene id: 28377:kcna7
uniprot id: A0A803TTA0
names: Subcellular Location Annotation
messages: Membrane

28377:pter
gene id: 28377:pter
uniprot id: G1KSW9
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:zfpm2
gene id: 28377:zfpm2
uniprot id: A0A803TT44
names: Subcellular Location Annotation
messages: Nucleus

28377:xpr1
gene id: 28377:xpr1
uniprot id: G1KDD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

28377:e2f8
gene id: 28377:e2f8
uniprot id: G1KRJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

28377:gabra6
gene id: 28377:gabra6
uniprot id: G1KQN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

28377:rdx
gene id: 28377:rdx
uniprot id: A0A803T3G2
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

28377:LOC100568176
gene id: 28377:LOC100568176
uniprot id: G1KBS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

28377:LOC100553301
gene id: 28377:LOC100553301
uniprot id: G1KHG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

28377:kif6
gene id: 28377:kif6
uniprot id: G1KAC6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

28377:dyrk1a
gene id: 28377:dyrk1a
uniprot id: G1KII2
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

28377:gucy1b3
gene id: 28377:gucy1b3
uniprot id: G1KTC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

28377:rplp1
gene id: 28377:rplp1
uniprot id: G1K8D7
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

28377:cachd1
gene id: 28377:cachd1
uniprot id: A0A803TZ28
uniprot id: G1KHS1
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

28377:atg4b
gene id: 28377:atg4b
uniprot id: G1K8U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Endoplasmic reticulum
messages: Mitochondrion
messages: autophagosome
messages: cytosol

28377:foxn2
gene id: 28377:foxn2
uniprot id: G1KPN1
names: Subcellular Location Annotation
messages: Nucleus

28377:bok
gene id: 28377:bok
uniprot id: G1K8X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

28377:chst3
gene id: 28377:chst3
uniprot id: G1KUD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

28377:rapgef2
gene id: 28377:rapgef2
uniprot id: A0A803SUD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAPGEF2 family.
messages: Cell junction
messages: Endosome
messages: Late endosome
messages: perinuclear region

28377:brox
gene id: 28377:brox
uniprot id: A0A803SYM4
uniprot id: G1KAP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BROX family.
messages: Membrane

28377:LOC100558604
gene id: 28377:LOC100558604
uniprot id: G1KNA9
uniprot id: R4GD94
names: Subcellular Location Annotation
messages: Membrane

28377:p2ry13
gene id: 28377:p2ry13
uniprot id: G1KUN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:traf6
gene id: 28377:traf6
uniprot id: A0A803T038
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family. A subfamily.
messages: Lipid droplet
messages: Nucleus
messages: cell cortex

28377:ncapg
gene id: 28377:ncapg
uniprot id: G1KAA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

28377:LOC100563006
gene id: 28377:LOC100563006
uniprot id: R4GBS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

28377:hpgd
gene id: 28377:hpgd
uniprot id: A0A803SZJ4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28377:cpne3
gene id: 28377:cpne3
uniprot id: G1KJN5
names: Similarity
messages: Belongs to the copine family.

28377:utp23
gene id: 28377:utp23
uniprot id: A0A803TDQ7
names: Subcellular Location Annotation
messages: nucleolus

28377:b3galnt1
gene id: 28377:b3galnt1
uniprot id: G1KGE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

28377:calhm2
gene id: 28377:calhm2
uniprot id: G1KDA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

28377:LOC100558470
gene id: 28377:LOC100558470
uniprot id: G1K8B0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:acss2
gene id: 28377:acss2
uniprot id: A0A803T8T3
uniprot id: G1KGH1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

28377:napb
gene id: 28377:napb
uniprot id: A0A803T190
uniprot id: G1KQP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

28377:LOC100558940
gene id: 28377:LOC100558940
uniprot id: A0A803T5I6
names: Similarity
messages: Belongs to the cytochrome P450 family.

28377:lmod1
gene id: 28377:lmod1
uniprot id: G1KDF7
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

28377:LOC100555907
gene id: 28377:LOC100555907
uniprot id: G1KRD1
names: Similarity
messages: Belongs to the cystatin family.

28377:pnpla4
gene id: 28377:pnpla4
uniprot id: G1K8H3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:snx10
gene id: 28377:snx10
uniprot id: A0A803T2K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

28377:cab39
gene id: 28377:cab39
uniprot id: G1KB07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

28377:cdc42bpa
gene id: 28377:cdc42bpa
uniprot id: G1KFT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: lamellipodium

28377:mpdz
gene id: 28377:mpdz
uniprot id: G1KL12
names: Subcellular Location Annotation
messages: tight junction

28377:cenpl
gene id: 28377:cenpl
uniprot id: G1KR38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-L/IML3 family.
messages: Nucleus

28377:LOC100561946
gene id: 28377:LOC100561946
uniprot id: G1KUY8
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

28377:vps37b
gene id: 28377:vps37b
uniprot id: H9GMN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

28377:oprl1
gene id: 28377:oprl1
uniprot id: A0A803SYE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
messages: Membrane
messages: Vesicle

28377:LOC103277978
gene id: 28377:LOC103277978
uniprot id: G1K8M7
uniprot id: G1K8T2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28377:efnb2
gene id: 28377:efnb2
uniprot id: A0A803TTX9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:slc11a1
gene id: 28377:slc11a1
uniprot id: A0A803TML1
uniprot id: G1KA06
names: Similarity
messages: Belongs to the NRAMP family.

28377:sec22c
gene id: 28377:sec22c
uniprot id: G1KFL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

28377:gal
gene id: 28377:gal
uniprot id: A0A803TG73
uniprot id: G1KPK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galanin family.
messages: Secreted

28377:dcbld1
gene id: 28377:dcbld1
uniprot id: G1KPP2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:gpr180
gene id: 28377:gpr180
uniprot id: G1KAU1
names: Subcellular Location Annotation
messages: Membrane

28377:ablim3
gene id: 28377:ablim3
uniprot id: G1KR80
names: Subcellular Location Annotation
messages: Cytoplasm

28377:itgb4
gene id: 28377:itgb4
uniprot id: A0A803U0K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

28377:foxp2
gene id: 28377:foxp2
uniprot id: G1KFZ6
names: Subcellular Location Annotation
messages: Nucleus

28377:npc2
gene id: 28377:npc2
uniprot id: A0A803SML8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPC2 family.
messages: Secreted

28377:sass6
gene id: 28377:sass6
uniprot id: G1KC00
names: Subcellular Location Annotation
messages: centrosome

28377:ssbp2
gene id: 28377:ssbp2
uniprot id: A0A803T347
uniprot id: R4GBL2
names: Subcellular Location Annotation
messages: Nucleus

28377:fignl1
gene id: 28377:fignl1
uniprot id: G1KY50
names: Similarity
messages: Belongs to the AAA ATPase family.

28377:ttc38
gene id: 28377:ttc38
uniprot id: G1KD52
names: Similarity
messages: Belongs to the TTC38 family.

28377:golt1a
gene id: 28377:golt1a
uniprot id: R4GBL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

28377:dph5
gene id: 28377:dph5
uniprot id: A0A803TD74
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

28377:ptx3
gene id: 28377:ptx3
uniprot id: A0A803SRQ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:strn
gene id: 28377:strn
uniprot id: A0A803TJS2
uniprot id: R4GDF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

28377:grpel1
gene id: 28377:grpel1
uniprot id: G1KA62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

28377:LOC100552862
gene id: 28377:LOC100552862
uniprot id: R4GAI6
names: Similarity
messages: Belongs to the intermediate filament family.

28377:mut
gene id: 28377:mut
uniprot id: G1KMV1
names: Function
names: Similarity
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.

28377:coq3
gene id: 28377:coq3
uniprot id: G1KK62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

28377:abt1
gene id: 28377:abt1
uniprot id: G1KFJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

28377:pfkfb1
gene id: 28377:pfkfb1
uniprot id: A0A803TQ15
uniprot id: G1KLB3
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

28377:mettl16
gene id: 28377:mettl16
uniprot id: G1KT98
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure.

28377:LOC100560423
gene id: 28377:LOC100560423
uniprot id: G1KC35
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

28377:ccr10
gene id: 28377:ccr10
uniprot id: G1KP85
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:LOC100554362
gene id: 28377:LOC100554362
uniprot id: G1KDI5
names: Similarity
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.

28377:c5h4orf47
gene id: 28377:c5h4orf47
uniprot id: G1KA78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0602 family.
messages: centrosome

28377:parvg
gene id: 28377:parvg
uniprot id: A0A803STC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

28377:LOC100566309
gene id: 28377:LOC100566309
uniprot id: A0A803SQI9
uniprot id: G1KJ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

28377:tmem161b
gene id: 28377:tmem161b
uniprot id: A0A803SRT1
uniprot id: G1K8K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

28377:pde6g
gene id: 28377:pde6g
uniprot id: G1KQM6
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

28377:mrpl42
gene id: 28377:mrpl42
uniprot id: G1KMI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL42 family.
messages: Mitochondrion

28377:rprd1a
gene id: 28377:rprd1a
uniprot id: A0A803T197
uniprot id: G1KFS5
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

28377:arsj
gene id: 28377:arsj
uniprot id: G1KLJ8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

28377:ehd4
gene id: 28377:ehd4
uniprot id: G1KQG3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

28377:egf
gene id: 28377:egf
uniprot id: A0A803SNT5
uniprot id: A0A803SU34
uniprot id: A0A803TYV4
uniprot id: G1KJV5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:atp4b
gene id: 28377:atp4b
uniprot id: A0A803SWM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

28377:myt1
gene id: 28377:myt1
uniprot id: A0A803T6M7
uniprot id: A0A803TZJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

28377:nup133
gene id: 28377:nup133
uniprot id: G1K922
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin Nup133 family.
messages: nuclear pore complex

28377:sgo1
gene id: 28377:sgo1
uniprot id: G1K849
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

28377:LOC103278845
gene id: 28377:LOC103278845
uniprot id: A0A803U182
names: Similarity
messages: Belongs to the apolipoprotein L family.

28377:tom1
gene id: 28377:tom1
uniprot id: G1KX91
names: Similarity
messages: Belongs to the TOM1 family.

28377:kat2b
gene id: 28377:kat2b
uniprot id: G1K850
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus
messages: centrosome

28377:mid1ip1
gene id: 28377:mid1ip1
uniprot id: G1KWB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

28377:bche
gene id: 28377:bche
uniprot id: A0A803T8U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

28377:clic5
gene id: 28377:clic5
uniprot id: G1KN71
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

28377:serinc3
gene id: 28377:serinc3
uniprot id: G1KT74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

28377:LOC100557540
gene id: 28377:LOC100557540
uniprot id: G1KE85
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:p4ha1
gene id: 28377:p4ha1
uniprot id: A0A803T0H2
uniprot id: G1K8Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

28377:eed
gene id: 28377:eed
uniprot id: G1KAU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ESC family.
messages: Nucleus

28377:ace
gene id: 28377:ace
uniprot id: G1KNF0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 2 Zn(2+) ions per subunit.

28377:pgm1
gene id: 28377:pgm1
uniprot id: G1KHK5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

28377:LOC100557660
gene id: 28377:LOC100557660
uniprot id: A0A803T425
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28377:trmu
gene id: 28377:trmu
uniprot id: G1KH08
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

28377:pdgfra
gene id: 28377:pdgfra
uniprot id: G1KK54
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Interacts with homodimeric PDGFA, PDGFB and PDGFC, and with heterodimers formed by PDGFA and PDGFB. Monomer in the absence of bound ligand.
messages: Membrane
messages: Present in an inactive conformation in the absence of bound ligand. Binding of PDGFA and/or PDGFB leads to dimerization and activation by autophosphorylation on tyrosine residues.
messages: Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.

28377:LOC103278024
gene id: 28377:LOC103278024
uniprot id: A0A803T4W6
names: Similarity
messages: Belongs to the ohanin/vespryn family.

28377:etnppl
gene id: 28377:etnppl
uniprot id: A0A803TRI4
uniprot id: G1KMJ9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

28377:pik3c2a
gene id: 28377:pik3c2a
uniprot id: G1K875
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

28377:tram1
gene id: 28377:tram1
uniprot id: G1KQI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

28377:asic4
gene id: 28377:asic4
uniprot id: A0A803TFB2
uniprot id: G1KPL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

28377:laptm4a
gene id: 28377:laptm4a
uniprot id: A0A803T9Q4
uniprot id: G1KPY6
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

28377:elavl3
gene id: 28377:elavl3
uniprot id: A0A803T4P2
uniprot id: A0A803T6G8
uniprot id: G1KTC3
names: Similarity
messages: Belongs to the RRM elav family.

28377:hspa8
gene id: 28377:hspa8
uniprot id: H9G9N5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

28377:arl1
gene id: 28377:arl1
uniprot id: G1KLB7
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

28377:kcnv1
gene id: 28377:kcnv1
uniprot id: G1KAW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.1/KCNV1 sub-subfamily.
messages: Heteromultimer with KCNB1 and KCNB2. Interacts with KCNC4 and KCND1.
messages: Membrane
messages: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.

28377:fggy
gene id: 28377:fggy
uniprot id: G1KG52
names: Similarity
messages: Belongs to the FGGY kinase family.

28377:LOC100552468
gene id: 28377:LOC100552468
uniprot id: L7N044
names: Similarity
messages: Belongs to the intermediate filament family.

28377:LOC100565293
gene id: 28377:LOC100565293
uniprot id: R4GDK2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28377:ATP6
gene id: 28377:ATP6
uniprot id: B3GSZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

28377:skap1
gene id: 28377:skap1
uniprot id: A0A803TUC9
uniprot id: G1KFG7
names: Similarity
messages: Belongs to the SKAP family.

28377:nab1
gene id: 28377:nab1
uniprot id: G1K8C5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

28377:LOC100568179
gene id: 28377:LOC100568179
uniprot id: A0A803SVA9
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

28377:nucb2
gene id: 28377:nucb2
uniprot id: A0A803SP67
uniprot id: G1K876
names: Similarity
messages: Belongs to the nucleobindin family.

28377:ppp1r9b
gene id: 28377:ppp1r9b
uniprot id: R4G978
names: Subcellular Location Annotation
messages: cytoskeleton

28377:tbp
gene id: 28377:tbp
uniprot id: G1KAY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

28377:chmp4b
gene id: 28377:chmp4b
uniprot id: G1KIA2
names: Similarity
messages: Belongs to the SNF7 family.

28377:tmed1
gene id: 28377:tmed1
uniprot id: G1KR35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

28377:tcp11
gene id: 28377:tcp11
uniprot id: G1KA00
names: Similarity
messages: Belongs to the TCP11 family.

28377:hao1
gene id: 28377:hao1
uniprot id: G1KBH8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

28377:tmeff2
gene id: 28377:tmeff2
uniprot id: G1KFP7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:zcchc11
gene id: 28377:zcchc11
uniprot id: G1KHK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

28377:fzd6
gene id: 28377:fzd6
uniprot id: G1KIU5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Cell surface
messages: Cytoplasmic vesicle membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:satb1
gene id: 28377:satb1
uniprot id: A0A803STW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

28377:ccdc126
gene id: 28377:ccdc126
uniprot id: A0A803TA74
names: Subcellular Location Annotation
messages: Secreted

28377:rnf168
gene id: 28377:rnf168
uniprot id: A0A803U145
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNF168 family.
messages: E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Nucleus
messages: The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).

28377:bak1
gene id: 28377:bak1
uniprot id: G1KSN2
names: Similarity
messages: Belongs to the Bcl-2 family.

28377:pigf
gene id: 28377:pigf
uniprot id: R4GDJ8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:usp9x
gene id: 28377:usp9x
uniprot id: G1KUK4
names: Similarity
messages: Belongs to the peptidase C19 family.

28377:tmem14a
gene id: 28377:tmem14a
uniprot id: G1KIE3
names: Similarity
messages: Belongs to the TMEM14 family.

28377:tnpo1
gene id: 28377:tnpo1
uniprot id: G1KJ76
names: Subcellular Location Annotation
messages: Cytoplasm

28377:arfgef1
gene id: 28377:arfgef1
uniprot id: A0A803TUZ0
uniprot id: G1KSI7
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

28377:ptger1
gene id: 28377:ptger1
uniprot id: G1KTE4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28377:adck2
gene id: 28377:adck2
uniprot id: G1KKX0
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

28377:LOC103278680
gene id: 28377:LOC103278680
uniprot id: A0A803SXS9
names: Similarity
messages: Belongs to the TRIM/RBCC family.

28377:ybey
gene id: 28377:ybey
uniprot id: G1KDH9
names: Similarity
messages: Belongs to the endoribonuclease YbeY family.

28377:LOC100564638
gene id: 28377:LOC100564638
uniprot id: G1KRK8
names: Similarity
messages: Belongs to the ohanin/vespryn family.

28377:slc45a4
gene id: 28377:slc45a4
uniprot id: G1K8N7
names: Subcellular Location Annotation
messages: Membrane

28377:gorasp1
gene id: 28377:gorasp1
uniprot id: G1KJ15
names: Similarity
messages: Belongs to the GORASP family.

28377:rock2
gene id: 28377:rock2
uniprot id: A0A803SRZ3
uniprot id: A0A803SWY4
uniprot id: A0A803TQY8
uniprot id: G1K8E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cell membrane
messages: Membrane
messages: centrosome

28377:mtr
gene id: 28377:mtr
uniprot id: G1KBM2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methylcob(III)alamin (MeCbl) to homocysteine, yielding enzyme-bound cob(I)alamin and methionine in the cytosol. MeCbl is an active form of cobalamin (vitamin B12) used as a cofactor for methionine biosynthesis. Cob(I)alamin form is regenerated to MeCbl by a transfer of a methyl group from 5-methyltetrahydrofolate. The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine.
messages: Cytoplasm
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

28377:prkaa1
gene id: 28377:prkaa1
uniprot id: A0A803T6Q0
uniprot id: G1KJX3
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

28377:hmgcs1
gene id: 28377:hmgcs1
uniprot id: A0A803T0X4
uniprot id: G1KKI9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

28377:cdh11
gene id: 28377:cdh11
uniprot id: H9GM15
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

28377:neto2
gene id: 28377:neto2
uniprot id: A0A803SWC0
uniprot id: H9GK82
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:LOC100565091
gene id: 28377:LOC100565091
uniprot id: M1ZMR2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

28377:slc1a1
gene id: 28377:slc1a1
uniprot id: A0A803TH92
uniprot id: G1KC01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

28377:slc25a26
gene id: 28377:slc25a26
uniprot id: G1KAQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

28377:igfbp3
gene id: 28377:igfbp3
uniprot id: A0A803TUV7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:gif
gene id: 28377:gif
uniprot id: G1KJI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

28377:yme1l1
gene id: 28377:yme1l1
uniprot id: G1KHA6
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

28377:LOC100559434
gene id: 28377:LOC100559434
uniprot id: G1KW27
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

28377:inpp4a
gene id: 28377:inpp4a
uniprot id: G1KML1
uniprot id: R4GBP4
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

28377:LOC103277804
gene id: 28377:LOC103277804
uniprot id: R4GA14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistin/FIZZ family.
messages: Secreted

28377:slc39a5
gene id: 28377:slc39a5
uniprot id: G1KVI4
names: Subcellular Location Annotation
messages: Membrane

28377:LOC100552501
gene id: 28377:LOC100552501
uniprot id: A0A803STP1
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

28377:LOC100557669
gene id: 28377:LOC100557669
uniprot id: G1KR50
names: Similarity
messages: Belongs to the peptidase S1 family. Snake venom subfamily.

28377:amdhd1
gene id: 28377:amdhd1
uniprot id: A0A803TRU7
uniprot id: G1KPF4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.

28377:mettl6
gene id: 28377:mettl6
uniprot id: G1KB69
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

28377:spib
gene id: 28377:spib
uniprot id: R4G9Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

28377:trip13
gene id: 28377:trip13
uniprot id: G1KIT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. PCH2 subfamily.
messages: Nucleus
messages: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.

28377:zfyve9
gene id: 28377:zfyve9
uniprot id: G1KHG2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Early endosome membrane

28377:ttll1
gene id: 28377:ttll1
uniprot id: A0A803TYI9
uniprot id: G1KRU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin polyglutamylase family.
messages: cilium basal body

28377:dirc2
gene id: 28377:dirc2
uniprot id: G1KDG9
names: Subcellular Location Annotation
messages: Membrane

28377:sft2d1
gene id: 28377:sft2d1
uniprot id: A0A803SKY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

28377:tomm7
gene id: 28377:tomm7
uniprot id: G1KPE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom7 family.
messages: Membrane
messages: Mitochondrion outer membrane

28377:pik3ca
gene id: 28377:pik3ca
uniprot id: G1KDE7
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

28377:r3hdml
gene id: 28377:r3hdml
uniprot id: G1KT36
names: Similarity
messages: Belongs to the CRISP family.

28377:spi1
gene id: 28377:spi1
uniprot id: A0A803SVU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

28377:LOC100556508
gene id: 28377:LOC100556508
uniprot id: G1KV96
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:dag1
gene id: 28377:dag1
uniprot id: A0A803SP95
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

28377:lhfpl4
gene id: 28377:lhfpl4
uniprot id: A0A803T3I2
uniprot id: A0A803TJI2
names: Subcellular Location Annotation
messages: Membrane

28377:psmd3
gene id: 28377:psmd3
uniprot id: G1KBP6
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

28377:dram2
gene id: 28377:dram2
uniprot id: R4G9P2
names: Subcellular Location Annotation
messages: Membrane

28377:pdhb
gene id: 28377:pdhb
uniprot id: A0A803TCJ3
uniprot id: G1KLD8
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

28377:LOC100559926
gene id: 28377:LOC100559926
uniprot id: G1KBT3
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

28377:lgalsl
gene id: 28377:lgalsl
uniprot id: G1K9N4
names: Function
messages: Does not bind lactose, and may not bind carbohydrates.

28377:msrb3
gene id: 28377:msrb3
uniprot id: A0A803THG1
uniprot id: A0A803TYD3
uniprot id: G1KBY3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

28377:pgm5
gene id: 28377:pgm5
uniprot id: G1K9N7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

28377:mat2b
gene id: 28377:mat2b
uniprot id: R4G925
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
messages: Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.
messages: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.

28377:c1galt1
gene id: 28377:c1galt1
uniprot id: G1KN54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.
messages: Membrane

28377:LOC100563808
gene id: 28377:LOC100563808
uniprot id: G1KUF8
names: Similarity
messages: Belongs to the intermediate filament family.

28377:LOC103278210
gene id: 28377:LOC103278210
uniprot id: G1KSC4
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

28377:LOC103278936
gene id: 28377:LOC103278936
uniprot id: G1KHA5
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

28377:phtf1
gene id: 28377:phtf1
uniprot id: G1K8C4
names: Subcellular Location Annotation
messages: Membrane

28377:LOC103283027
gene id: 28377:LOC103283027
uniprot id: G1KXU3
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

28377:zfx
gene id: 28377:zfx
uniprot id: G1KGC2
names: Subcellular Location Annotation
messages: Nucleus

28377:dbt
gene id: 28377:dbt
uniprot id: R4GCR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

28377:chd9
gene id: 28377:chd9
uniprot id: H9GN21
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

28377:mfsd4b
gene id: 28377:mfsd4b
uniprot id: G1KL55
names: Subcellular Location Annotation
messages: Membrane

28377:adgb
gene id: 28377:adgb
uniprot id: G1KGC3
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:ube2d2
gene id: 28377:ube2d2
uniprot id: G1KAB3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

28377:LOC100565228
gene id: 28377:LOC100565228
uniprot id: A0A803TEJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

28377:abi3
gene id: 28377:abi3
uniprot id: G1KF21
names: Similarity
messages: Belongs to the ABI family.

28377:hoxc6
gene id: 28377:hoxc6
uniprot id: G1KKM7
names: Subcellular Location Annotation
messages: Nucleus

28377:bmp2
gene id: 28377:bmp2
uniprot id: A0A803SPC0
names: Similarity
messages: Belongs to the TGF-beta family.

28377:rars2
gene id: 28377:rars2
uniprot id: G1KQM3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

28377:galnt15
gene id: 28377:galnt15
uniprot id: G1KGZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

28377:lhfpl3
gene id: 28377:lhfpl3
uniprot id: A0A803T8S2
uniprot id: G1KK04
names: Subcellular Location Annotation
messages: Membrane

28377:dclk3
gene id: 28377:dclk3
uniprot id: G1KJT0
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

28377:mettl10
gene id: 28377:mettl10
uniprot id: A0A803SMA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: Nucleus
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'.

28377:psip1
gene id: 28377:psip1
uniprot id: G1KUD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

28377:cntf
gene id: 28377:cntf
uniprot id: G1KFR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

28377:flvcr2
gene id: 28377:flvcr2
uniprot id: A0A803SMW4
uniprot id: G1KTC7
names: Subcellular Location Annotation
messages: Membrane

28377:sptssa
gene id: 28377:sptssa
uniprot id: A0A803TJZ1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:LOC100562595
gene id: 28377:LOC100562595
uniprot id: A0A803TUP6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

28377:aqr
gene id: 28377:aqr
uniprot id: G1K915
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWF11 family.
messages: Nucleus

28377:chodl
gene id: 28377:chodl
uniprot id: G1KQD4
names: Subcellular Location Annotation
messages: Secreted

28377:kcnv2
gene id: 28377:kcnv2
uniprot id: G1KBK6
names: Subcellular Location Annotation
messages: Membrane

28377:rhbdd1
gene id: 28377:rhbdd1
uniprot id: G1KC94
names: Subcellular Location Annotation
messages: Membrane

28377:map2k4
gene id: 28377:map2k4
uniprot id: A0A803TC26
uniprot id: G1KTZ0
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:coch
gene id: 28377:coch
uniprot id: G1KQD9
names: Function
messages: Plays a role in the control of cell shape and motility in the trabecular meshwork.

28377:LOC100559320
gene id: 28377:LOC100559320
uniprot id: G1KK66
names: Similarity
messages: Belongs to the ohanin/vespryn family.

28377:cdk4
gene id: 28377:cdk4
uniprot id: A0A803T5Z1
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:spcs3
gene id: 28377:spcs3
uniprot id: A0A803T7V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane

28377:hoxc4
gene id: 28377:hoxc4
uniprot id: G1KKN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

28377:ambn
gene id: 28377:ambn
uniprot id: A0A0K2GMW1
uniprot id: A0A803TIS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ameloblastin family.
messages: Involved in the mineralization and structural organization of enamel.
messages: extracellular matrix

28377:mcrip1
gene id: 28377:mcrip1
uniprot id: G1KKC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

28377:LOC100565285
gene id: 28377:LOC100565285
uniprot id: R4G9Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPEG1 family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

28377:sumf1
gene id: 28377:sumf1
uniprot id: G1KJZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

28377:plxnb1
gene id: 28377:plxnb1
uniprot id: G1KK91
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:grhl1
gene id: 28377:grhl1
uniprot id: A0A803TKT8
names: Subcellular Location Annotation
messages: Nucleus

28377:ror1
gene id: 28377:ror1
uniprot id: G1KHM7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:dpysl4
gene id: 28377:dpysl4
uniprot id: G1KH68
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

28377:LOC100552057
gene id: 28377:LOC100552057
uniprot id: G1KDC5
names: Similarity
messages: Belongs to the HEBP family.

28377:LOC100552069
gene id: 28377:LOC100552069
uniprot id: G1K865
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A13 subfamily.
messages: Cell membrane
messages: Membrane

28377:kdm4a
gene id: 28377:kdm4a
uniprot id: G1KPP0
names: Similarity
messages: Belongs to the JHDM3 histone demethylase family.

28377:camk2d
gene id: 28377:camk2d
uniprot id: A0A803SS99
uniprot id: A0A803SX49
uniprot id: A0A803TV78
uniprot id: L7MZX9
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

28377:impact
gene id: 28377:impact
uniprot id: G1K9U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

28377:shoc2
gene id: 28377:shoc2
uniprot id: G1KRP6
names: Function
names: Similarity
messages: Belongs to the SHOC2 family.
messages: Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.

28377:tmem91
gene id: 28377:tmem91
uniprot id: H9G821
names: Similarity
messages: Belongs to the CD225/Dispanin family.

28377:gar1
gene id: 28377:gar1
uniprot id: G1KJM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

28377:rnaseh2b
gene id: 28377:rnaseh2b
uniprot id: G1KLE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H2 subunit B family.
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus
messages: The RNase H2 complex is a heterotrimer composed of the catalytic subunit RNASEH2A and the non-catalytic subunits RNASEH2B and RNASEH2C.

28377:dpf3
gene id: 28377:dpf3
uniprot id: G1KSJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the requiem/DPF family.
messages: Nucleus

28377:txnrd3
gene id: 28377:txnrd3
uniprot id: G1KPH0
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.

28377:tceanc2
gene id: 28377:tceanc2
uniprot id: A0A803T6D4
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC100337544
gene id: 28377:LOC100337544
uniprot id: B6Z1W4
names: Similarity
messages: Belongs to the intermediate filament family.

28377:tmem63a
gene id: 28377:tmem63a
uniprot id: G1KEV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

28377:LOC103279270
gene id: 28377:LOC103279270
uniprot id: G1KF75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.
messages: Secreted

28377:gars
gene id: 28377:gars
uniprot id: G1KEH7
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

28377:vps35
gene id: 28377:vps35
uniprot id: H9GJW8
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

28377:carm1
gene id: 28377:carm1
uniprot id: A0A803TVL8
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC100567311
gene id: 28377:LOC100567311
uniprot id: G1KML6
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

28377:llgl2
gene id: 28377:llgl2
uniprot id: G1KFR8
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

28377:gata5
gene id: 28377:gata5
uniprot id: G1KDJ4
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC100564182
gene id: 28377:LOC100564182
uniprot id: G1KUI4
names: Similarity
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.

28377:pitx2
gene id: 28377:pitx2
uniprot id: A0A803T1S7
uniprot id: G1KUT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

28377:itgb8
gene id: 28377:itgb8
uniprot id: A0A803U1L3
uniprot id: G1KLF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

28377:c8a
gene id: 28377:c8a
uniprot id: G1KFV6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:gdap1
gene id: 28377:gdap1
uniprot id: A0A803SPZ1
names: Similarity
messages: Belongs to the GST superfamily.

28377:slc30a5
gene id: 28377:slc30a5
uniprot id: G1KSJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Membrane
messages: trans-Golgi network membrane

28377:lactb2
gene id: 28377:lactb2
uniprot id: G1KQC0
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

28377:ebna1bp2
gene id: 28377:ebna1bp2
uniprot id: G1KNE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: Required for the processing of the 27S pre-rRNA.
messages: nucleolus

28377:nt5c3a
gene id: 28377:nt5c3a
uniprot id: A0A803T217
uniprot id: G1KIT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

28377:LOC100560836
gene id: 28377:LOC100560836
uniprot id: A0A803TNC6
names: Similarity
messages: Belongs to the CFAP97 family.

28377:pitpnm2
gene id: 28377:pitpnm2
uniprot id: H9GMK4
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

28377:rpf2
gene id: 28377:rpf2
uniprot id: G1KL21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

28377:fam49b
gene id: 28377:fam49b
uniprot id: G1KK20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

28377:ska3
gene id: 28377:ska3
uniprot id: A0A803TMK8
uniprot id: A0A803TXM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA3 family.
messages: kinetochore
messages: spindle

28377:ints10
gene id: 28377:ints10
uniprot id: A0A803SZM5
uniprot id: G1KII5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 10 family.
messages: Nucleus

28377:serpinc1
gene id: 28377:serpinc1
uniprot id: G1KR22
names: Similarity
messages: Belongs to the serpin family.

28377:aarsd1
gene id: 28377:aarsd1
uniprot id: R4GCQ3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.

28377:slc26a5
gene id: 28377:slc26a5
uniprot id: G1KFT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

28377:LOC103279063
gene id: 28377:LOC103279063
uniprot id: A0A803TQS8
names: Similarity
messages: Belongs to the FAM47 family.

28377:fam151b
gene id: 28377:fam151b
uniprot id: G1KK61
names: Similarity
messages: Belongs to the FAM151 family.

28377:pvalb
gene id: 28377:pvalb
uniprot id: G1KSC8
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

28377:gdf5
gene id: 28377:gdf5
uniprot id: G1KEJ5
names: Similarity
messages: Belongs to the TGF-beta family.

28377:prok1
gene id: 28377:prok1
uniprot id: A0A803TFD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

28377:susd4
gene id: 28377:susd4
uniprot id: G1KAS8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:fam19a3
gene id: 28377:fam19a3
uniprot id: A0A803SL83
names: Similarity
messages: Belongs to the TAFA family.

28377:LOC103277689
gene id: 28377:LOC103277689
uniprot id: G1KWE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

28377:LOC100555331
gene id: 28377:LOC100555331
uniprot id: G1KG10
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Snake venom subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:fut8
gene id: 28377:fut8
uniprot id: G1KA08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 23 family.
messages: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
messages: Golgi stack membrane
messages: Membrane

28377:LOC100559769
gene id: 28377:LOC100559769
uniprot id: R4G9M7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:clk1
gene id: 28377:clk1
uniprot id: G1KTF0
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:prkar2b
gene id: 28377:prkar2b
uniprot id: G1KQJ7
names: Similarity
messages: Belongs to the cAMP-dependent kinase regulatory chain family.

28377:pyroxd2
gene id: 28377:pyroxd2
uniprot id: G1KBU8
names: Similarity
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.

28377:sesn3
gene id: 28377:sesn3
uniprot id: G1KPC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

28377:gtf2b
gene id: 28377:gtf2b
uniprot id: G1K9D7
names: Similarity
messages: Belongs to the TFIIB family.

28377:cfap97
gene id: 28377:cfap97
uniprot id: G1KAJ3
names: Similarity
messages: Belongs to the CFAP97 family.

28377:c3h11orf87
gene id: 28377:c3h11orf87
uniprot id: G1KY40
names: Subcellular Location Annotation
messages: Membrane

28377:supt3h
gene id: 28377:supt3h
uniprot id: A0A803SY65
uniprot id: G1KN25
names: Subcellular Location Annotation
messages: Nucleus

28377:tnfsf11
gene id: 28377:tnfsf11
uniprot id: A0A803SXH1
names: Similarity
messages: Belongs to the tumor necrosis factor family.

28377:parp11
gene id: 28377:parp11
uniprot id: A0A803T3P8
names: Similarity
messages: Belongs to the ARTD/PARP family.

28377:ddc
gene id: 28377:ddc
uniprot id: G1KHR5
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

28377:dmbx1
gene id: 28377:dmbx1
uniprot id: G1KA14
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC100564568
gene id: 28377:LOC100564568
uniprot id: G1KMU4
names: Similarity
messages: Belongs to the BicD family.

28377:LOC100559260
gene id: 28377:LOC100559260
uniprot id: G1KF19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

28377:hnf4g
gene id: 28377:hnf4g
uniprot id: G1KNJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

28377:pdcd11
gene id: 28377:pdcd11
uniprot id: G1KDA1
names: Subcellular Location Annotation
messages: nucleolus

28377:bccip
gene id: 28377:bccip
uniprot id: G1K8V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: spindle pole

28377:cftr
gene id: 28377:cftr
uniprot id: G1KHB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
messages: Recycling endosome membrane

28377:LOC103279244
gene id: 28377:LOC103279244
uniprot id: G1KS08
names: Similarity
messages: Belongs to the intermediate filament family.

28377:LOC100556910
gene id: 28377:LOC100556910
uniprot id: A0A803T9G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

28377:ube3a
gene id: 28377:ube3a
uniprot id: G1KLV9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
messages: Nucleus

28377:fgd1
gene id: 28377:fgd1
uniprot id: A0A803SWV0
uniprot id: G1KME2
names: Subcellular Location Annotation
messages: cytoskeleton

28377:eif3m
gene id: 28377:eif3m
uniprot id: G1KAY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

28377:nup210
gene id: 28377:nup210
uniprot id: G1KMY0
names: Similarity
messages: Belongs to the NUP210 family.

28377:sim1
gene id: 28377:sim1
uniprot id: G1KJZ0
names: Subcellular Location Annotation
messages: Nucleus

28377:vangl1
gene id: 28377:vangl1
uniprot id: G1KBK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

28377:gpr182
gene id: 28377:gpr182
uniprot id: G1KGG2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:ppp2r2c
gene id: 28377:ppp2r2c
uniprot id: A0A803SWT2
uniprot id: A0A803TXJ3
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

28377:dph3
gene id: 28377:dph3
uniprot id: G1KGZ9
names: Similarity
messages: Belongs to the DPH3 family.

28377:cant1
gene id: 28377:cant1
uniprot id: G1KSA6
names: Similarity
messages: Belongs to the apyrase family.

28377:cap2
gene id: 28377:cap2
uniprot id: G1KCH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane

28377:rybp
gene id: 28377:rybp
uniprot id: A0A803TAL8
uniprot id: G1KQ99
names: Subcellular Location Annotation
messages: Nucleus

28377:gpm6b
gene id: 28377:gpm6b
uniprot id: A0A803SPU6
uniprot id: A0A803TEX1
uniprot id: A0A803TXP0
uniprot id: G1KA16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

28377:map3k9
gene id: 28377:map3k9
uniprot id: A0A803SVK2
uniprot id: G1KDB6
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

28377:LOC100557356
gene id: 28377:LOC100557356
uniprot id: G1KK17
names: Subcellular Location Annotation
messages: Membrane

28377:appl1
gene id: 28377:appl1
uniprot id: G1KEI9
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Nucleus
messages: phagosome
messages: ruffle

28377:fbxo25
gene id: 28377:fbxo25
uniprot id: G1KDX9
uniprot id: R4GBM6
names: Subcellular Location Annotation
messages: Nucleus

28377:c4h20orf24
gene id: 28377:c4h20orf24
uniprot id: G1KJ79
names: Subcellular Location Annotation
messages: Membrane

28377:b4galt2
gene id: 28377:b4galt2
uniprot id: G1KPW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

28377:dpy19l4
gene id: 28377:dpy19l4
uniprot id: G1KCA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

28377:tfdp1
gene id: 28377:tfdp1
uniprot id: G1K8K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

28377:LOC100562947
gene id: 28377:LOC100562947
uniprot id: G1KUS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

28377:hmx2
gene id: 28377:hmx2
uniprot id: G1KU05
names: Subcellular Location Annotation
messages: Nucleus

28377:aspdh
gene id: 28377:aspdh
uniprot id: G1KLT7
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.

28377:elovl6
gene id: 28377:elovl6
uniprot id: A0A803T7R7
uniprot id: A0A803TM80
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

28377:tfap2d
gene id: 28377:tfap2d
uniprot id: G1KDY1
names: Similarity
messages: Belongs to the AP-2 family.

28377:irak1bp1
gene id: 28377:irak1bp1
uniprot id: G1KD55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

28377:trmt6
gene id: 28377:trmt6
uniprot id: G1K8L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

28377:tmbim1
gene id: 28377:tmbim1
uniprot id: A0A803SWD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

28377:spdef
gene id: 28377:spdef
uniprot id: G1KRL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

28377:tlx3
gene id: 28377:tlx3
uniprot id: A0A803SX43
uniprot id: A0A803T5Y3
names: Subcellular Location Annotation
messages: Nucleus

28377:gcsh
gene id: 28377:gcsh
uniprot id: H9GEJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

28377:hspa2
gene id: 28377:hspa2
uniprot id: G1KRK2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

28377:LOC100565705
gene id: 28377:LOC100565705
uniprot id: A0A803SX99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

28377:tsg101
gene id: 28377:tsg101
uniprot id: G1K889
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

28377:LOC100556109
gene id: 28377:LOC100556109
uniprot id: G1KMA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

28377:bivm
gene id: 28377:bivm
uniprot id: G1KB98
names: Similarity
messages: Belongs to the BIVM family.

28377:fam19a5
gene id: 28377:fam19a5
uniprot id: A0A803T4Z1
uniprot id: A0A803T529
names: Similarity
messages: Belongs to the TAFA family.

28377:slc16a3
gene id: 28377:slc16a3
uniprot id: G1KAX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

28377:drd1
gene id: 28377:drd1
uniprot id: G1KQJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:ndp
gene id: 28377:ndp
uniprot id: G1KUH6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:cmtr1
gene id: 28377:cmtr1
uniprot id: G1KQ10
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1).
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.

28377:fam53c
gene id: 28377:fam53c
uniprot id: G1KG13
names: Similarity
messages: Belongs to the FAM53 family.

28377:rbpjl
gene id: 28377:rbpjl
uniprot id: G1KMB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

28377:fam206a
gene id: 28377:fam206a
uniprot id: G1K9Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABITRAM family.
messages: growth cone
messages: lamellipodium

28377:zdhhc11
gene id: 28377:zdhhc11
uniprot id: A0A803T4Z4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

28377:kdm1b
gene id: 28377:kdm1b
uniprot id: G1KBR2
names: Similarity
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.

28377:LOC100562555
gene id: 28377:LOC100562555
uniprot id: G1KSP0
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

28377:kcnk12
gene id: 28377:kcnk12
uniprot id: G1KPF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

28377:slc25a15
gene id: 28377:slc25a15
uniprot id: G1KSW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

28377:cnih4
gene id: 28377:cnih4
uniprot id: G1KE58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

28377:dll1
gene id: 28377:dll1
uniprot id: G1KB45
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

28377:sphkap
gene id: 28377:sphkap
uniprot id: G1KQD8
names: Similarity
messages: Belongs to the AKAP110 family.

28377:myadml2
gene id: 28377:myadml2
uniprot id: L7MZV6
names: Subcellular Location Annotation
messages: Membrane

28377:phlda3
gene id: 28377:phlda3
uniprot id: G1KC58
names: Subcellular Location Annotation
messages: Cytoplasm

28377:ndufaf7
gene id: 28377:ndufaf7
uniprot id: A0A803TGP0
uniprot id: G1K9D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

28377:jak1
gene id: 28377:jak1
uniprot id: G1KI54
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.

28377:gpat3
gene id: 28377:gpat3
uniprot id: A0A803U0B7
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

28377:vta1
gene id: 28377:vta1
uniprot id: G1KHT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

28377:LOC100565889
gene id: 28377:LOC100565889
uniprot id: R4GD57
names: Subcellular Location Annotation
messages: Secreted

28377:pabpc1l
gene id: 28377:pabpc1l
uniprot id: G1KLR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

28377:urod
gene id: 28377:urod
uniprot id: G1KQY1
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

28377:dhx8
gene id: 28377:dhx8
uniprot id: G1KP21
names: Subcellular Location Annotation
messages: Nucleus

28377:kcnq1
gene id: 28377:kcnq1
uniprot id: A0A803SQK8
uniprot id: R4GA42
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum
messages: Lateral cell membrane
messages: Membrane
messages: Membrane raft

28377:gdf6
gene id: 28377:gdf6
uniprot id: R4GCR5
names: Similarity
messages: Belongs to the TGF-beta family.

28377:rpl27
gene id: 28377:rpl27
uniprot id: G1KNX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

28377:cldn12
gene id: 28377:cldn12
uniprot id: G1KRP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Membrane
messages: tight junction

28377:LOC100560644
gene id: 28377:LOC100560644
uniprot id: G1KAC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRH/QCR6 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

28377:nbn
gene id: 28377:nbn
uniprot id: G1KK41
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
messages: Component of the MRN complex.
messages: Nucleus
messages: telomere

28377:mrs2
gene id: 28377:mrs2
uniprot id: G1KB99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

28377:gdap1l1
gene id: 28377:gdap1l1
uniprot id: A0A803THX4
names: Similarity
messages: Belongs to the GST superfamily.

28377:pspc1
gene id: 28377:pspc1
uniprot id: G1KAB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PSPC family.
messages: Cytoplasm
messages: Nucleus matrix
messages: Nucleus speckle
messages: nucleolus

28377:plch1
gene id: 28377:plch1
uniprot id: A0A803SZW4
uniprot id: G1KCL6
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

28377:polh
gene id: 28377:polh
uniprot id: G1KJL3
names: Subcellular Location Annotation
messages: Nucleus

28377:plpp3
gene id: 28377:plpp3
uniprot id: G1K8D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

28377:rpl19
gene id: 28377:rpl19
uniprot id: A0A803SMV5
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

28377:lmbr1
gene id: 28377:lmbr1
uniprot id: G1KKY1
names: Similarity
messages: Belongs to the LIMR family.

28377:creb3l2
gene id: 28377:creb3l2
uniprot id: G1KLG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family. ATF subfamily.
messages: Binds DNA as a dimer.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

28377:ict1
gene id: 28377:ict1
uniprot id: G1KEY2
names: Subcellular Location Annotation
messages: Mitochondrion

28377:renbp
gene id: 28377:renbp
uniprot id: G1KM50
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

28377:st3gal3
gene id: 28377:st3gal3
uniprot id: A0A803TVM0
uniprot id: A0A803U022
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

28377:trmt13
gene id: 28377:trmt13
uniprot id: G1KBZ1
names: Function
names: Similarity
messages: Belongs to the methyltransferase TRM13 family.
messages: tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

28377:slc30a1
gene id: 28377:slc30a1
uniprot id: G1KSH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

28377:dnah10
gene id: 28377:dnah10
uniprot id: H9GM01
names: Similarity
messages: Belongs to the dynein heavy chain family.

28377:LOC100555644
gene id: 28377:LOC100555644
uniprot id: A0A803T4S2
uniprot id: G1KPB0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

28377:pdxk
gene id: 28377:pdxk
uniprot id: G1KUF2
names: Similarity
messages: Belongs to the pyridoxine kinase family.

28377:pfkfb3
gene id: 28377:pfkfb3
uniprot id: A0A803TSP4
uniprot id: A0A803TT92
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

28377:a4galt
gene id: 28377:a4galt
uniprot id: G1KS37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

28377:ywhab
gene id: 28377:ywhab
uniprot id: G1KLJ0
names: Similarity
messages: Belongs to the 14-3-3 family.

28377:chrm5
gene id: 28377:chrm5
uniprot id: G1KXM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

28377:atp6v0a1
gene id: 28377:atp6v0a1
uniprot id: A0A803SPA5
uniprot id: G1KUJ8
uniprot id: R4GD75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

28377:LOC100552532
gene id: 28377:LOC100552532
uniprot id: A0A803T5K5
uniprot id: G1KP27
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

28377:zfyve27
gene id: 28377:zfyve27
uniprot id: A0A803TFU6
uniprot id: G1KBH4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: growth cone membrane

28377:ddx47
gene id: 28377:ddx47
uniprot id: G1KKF6
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

28377:pms1
gene id: 28377:pms1
uniprot id: G1KCK9
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

28377:med8
gene id: 28377:med8
uniprot id: G1KNT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.
messages: Component of the Mediator complex.
messages: Nucleus

28377:nol10
gene id: 28377:nol10
uniprot id: G1KMW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

28377:il17d
gene id: 28377:il17d
uniprot id: A0A803T2E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

28377:epor
gene id: 28377:epor
uniprot id: G1KT92
names: Subcellular Location Annotation
messages: Membrane

28377:copb2
gene id: 28377:copb2
uniprot id: G1KBX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

28377:wee2
gene id: 28377:wee2
uniprot id: G1KL87
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

28377:mical1
gene id: 28377:mical1
uniprot id: G1KIU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
messages: Cytoplasm

28377:rab33b
gene id: 28377:rab33b
uniprot id: G1KAE4
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

28377:vprbp
gene id: 28377:vprbp
uniprot id: G1KGY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPRBP/DCAF1 family.
messages: Nucleus

28377:sf3b6
gene id: 28377:sf3b6
uniprot id: G1KLC2
names: Subcellular Location Annotation
messages: Nucleus

28377:cebpb
gene id: 28377:cebpb
uniprot id: G1KR93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

28377:tert
gene id: 28377:tert
uniprot id: A0A803STA3
uniprot id: G1K9H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

28377:atxn10
gene id: 28377:atxn10
uniprot id: G1KPT2
names: Function
names: Similarity
messages: Belongs to the ataxin-10 family.
messages: Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.

28377:dynlrb1
gene id: 28377:dynlrb1
uniprot id: A0A803U0H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: cytoskeleton

28377:pclo
gene id: 28377:pclo
uniprot id: A0A803TK82
uniprot id: G1KS77
names: Subcellular Location Annotation
messages: Presynaptic active zone

28377:wasf1
gene id: 28377:wasf1
uniprot id: G1KKG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

28377:frk
gene id: 28377:frk
uniprot id: G1KMB1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

28377:amer2
gene id: 28377:amer2
uniprot id: G1KBR9
names: Similarity
messages: Belongs to the Amer family.

28377:lix1
gene id: 28377:lix1
uniprot id: G1KLQ5
names: Similarity
messages: Belongs to the LIX1 family.

28377:eif1ax
gene id: 28377:eif1ax
uniprot id: G1KML8
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

28377:tv23b
gene id: 28377:tv23b
uniprot id: G1KU77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

28377:tpd52l2
gene id: 28377:tpd52l2
uniprot id: A0A803T3S1
uniprot id: G1KC50
names: Similarity
messages: Belongs to the TPD52 family.

28377:LOC100551599
gene id: 28377:LOC100551599
uniprot id: G1KWI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

28377:LOC100552374
gene id: 28377:LOC100552374
uniprot id: G1KBP7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

28377:plcb4
gene id: 28377:plcb4
uniprot id: G1KAY9
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

28377:lin7b
gene id: 28377:lin7b
uniprot id: A0A803TWT8
uniprot id: G1KNG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

28377:trim67
gene id: 28377:trim67
uniprot id: G1KAM1
names: Subcellular Location Annotation
messages: cytoskeleton

28377:LOC103278849
gene id: 28377:LOC103278849
uniprot id: A0A803SQV0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

28377:mmaa
gene id: 28377:mmaa
uniprot id: G1KC15
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

28377:LOC100562999
gene id: 28377:LOC100562999
uniprot id: G1KLM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

28377:map1lc3a
gene id: 28377:map1lc3a
uniprot id: G1KIS9
names: Similarity
messages: Belongs to the ATG8 family.

28377:nr2c1
gene id: 28377:nr2c1
uniprot id: G1KMY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

28377:gabbr1
gene id: 28377:gabbr1
uniprot id: G1KKP4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:uba1
gene id: 28377:uba1
uniprot id: G1KE14
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

28377:katnal2
gene id: 28377:katnal2
uniprot id: G1KLT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily.
messages: Cytoplasm
messages: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
messages: cytoskeleton
messages: spindle
messages: spindle pole

28377:nobox
gene id: 28377:nobox
uniprot id: G1KA94
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC100561551
gene id: 28377:LOC100561551
uniprot id: G1KSQ9
names: Similarity
messages: Belongs to the cytochrome P450 family.

28377:gcnt1
gene id: 28377:gcnt1
uniprot id: G1KE93
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

28377:bcat1
gene id: 28377:bcat1
uniprot id: A0A803SL94
uniprot id: G1KTU1
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

28377:shroom3
gene id: 28377:shroom3
uniprot id: A0A803TWN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

28377:LOC100565965
gene id: 28377:LOC100565965
uniprot id: G1KBT2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

28377:fbln1
gene id: 28377:fbln1
uniprot id: G1KQ48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

28377:wdr55
gene id: 28377:wdr55
uniprot id: A0A803T2B8
uniprot id: A0A803U189
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR55 family.
messages: Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis.
messages: nucleolus

28377:smad1
gene id: 28377:smad1
uniprot id: G1KC06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

28377:ltv1
gene id: 28377:ltv1
uniprot id: A0A803TN78
uniprot id: G1KH95
names: Similarity
messages: Belongs to the LTV1 family.

28377:gfra3
gene id: 28377:gfra3
uniprot id: G1KFX7
names: Similarity
messages: Belongs to the GDNFR family.

28377:met
gene id: 28377:met
uniprot id: G1KI46
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:smpdl3a
gene id: 28377:smpdl3a
uniprot id: G1K9M3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

28377:lama3
gene id: 28377:lama3
uniprot id: G1K957
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:LOC100558194
gene id: 28377:LOC100558194
uniprot id: A0A803TN37
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

28377:arf1
gene id: 28377:arf1
uniprot id: G1KFW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

28377:dxo
gene id: 28377:dxo
uniprot id: G1KLV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Binds 2 magnesium ions.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

28377:xylt2
gene id: 28377:xylt2
uniprot id: G1KDY5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

28377:iapp
gene id: 28377:iapp
uniprot id: G1KTW7
names: Similarity
messages: Belongs to the calcitonin family.

28377:ndufa12
gene id: 28377:ndufa12
uniprot id: G1KMR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

28377:tmem86a
gene id: 28377:tmem86a
uniprot id: G1K892
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

28377:atp6v1c2
gene id: 28377:atp6v1c2
uniprot id: G1KN14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

28377:rnf7
gene id: 28377:rnf7
uniprot id: A0A803T8X5
names: Similarity
messages: Belongs to the RING-box family.

28377:acp5
gene id: 28377:acp5
uniprot id: G1KTF9
names: Cofactor
messages: Binds 2 iron ions per subunit.

28377:lsm3
gene id: 28377:lsm3
uniprot id: G1KNV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

28377:mpp3
gene id: 28377:mpp3
uniprot id: G1KD43
names: Similarity
messages: Belongs to the MAGUK family.

28377:galk1
gene id: 28377:galk1
uniprot id: G1KGC6
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

28377:col4a3bp
gene id: 28377:col4a3bp
uniprot id: A0A803TFU0
uniprot id: G1KI18
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

28377:myo6
gene id: 28377:myo6
uniprot id: A0A803TNN6
uniprot id: A0A803TWI5
uniprot id: G1KDE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: clathrin-coated pit
messages: clathrin-coated vesicle
messages: filopodium
messages: microvillus

28377:igf2bp3
gene id: 28377:igf2bp3
uniprot id: G1KNZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Cytoplasm
messages: Nucleus

28377:fut4
gene id: 28377:fut4
uniprot id: G1KPG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

28377:dram1
gene id: 28377:dram1
uniprot id: G1KSS7
names: Subcellular Location Annotation
messages: Membrane

28377:LOC100563524
gene id: 28377:LOC100563524
uniprot id: R4G9W1
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

28377:LOC100557218
gene id: 28377:LOC100557218
uniprot id: G1KTX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCO1/2 family.
messages: Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.
messages: Homodimer.
messages: Mitochondrion inner membrane

28377:LOC100560252
gene id: 28377:LOC100560252
uniprot id: G1KRJ2
names: Similarity
messages: Belongs to the folate receptor family.

28377:pparg
gene id: 28377:pparg
uniprot id: G1KNP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Cytoplasm
messages: Heterodimer with other nuclear receptors.
messages: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. May play a role in the regulation of circadian rhythm.
messages: Nucleus

28377:acyp1
gene id: 28377:acyp1
uniprot id: G1KT64
names: Similarity
messages: Belongs to the acylphosphatase family.

28377:batf
gene id: 28377:batf
uniprot id: G1KTB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

28377:grb7
gene id: 28377:grb7
uniprot id: A0A803SMR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

28377:LOC100558522
gene id: 28377:LOC100558522
uniprot id: G1KTH4
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion membrane

28377:hdac4
gene id: 28377:hdac4
uniprot id: A0A803T4T9
uniprot id: A0A803T8I1
uniprot id: G1KJ78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

28377:kif21a
gene id: 28377:kif21a
uniprot id: G1KHC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

28377:syt1
gene id: 28377:syt1
uniprot id: G1KPD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

28377:ppa1
gene id: 28377:ppa1
uniprot id: A0A803TF59
names: Similarity
messages: Belongs to the PPase family.

28377:hmgcr
gene id: 28377:hmgcr
uniprot id: G1KI99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane

28377:rwdd3
gene id: 28377:rwdd3
uniprot id: G1KD60
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

28377:eps8l2
gene id: 28377:eps8l2
uniprot id: G1KQU8
names: Similarity
messages: Belongs to the EPS8 family.

28377:f12
gene id: 28377:f12
uniprot id: G1KF85
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Snake venom subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:syn2
gene id: 28377:syn2
uniprot id: G1KNS8
names: Similarity
messages: Belongs to the synapsin family.

28377:neto1
gene id: 28377:neto1
uniprot id: G1KC92
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:ctdp1
gene id: 28377:ctdp1
uniprot id: G1KVK5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

28377:tm4sf19
gene id: 28377:tm4sf19
uniprot id: G1K8H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

28377:ntsr1
gene id: 28377:ntsr1
uniprot id: G1KX65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:LOC100554364
gene id: 28377:LOC100554364
uniprot id: R4GCN4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

28377:capn2
gene id: 28377:capn2
uniprot id: A0A803TYH8
uniprot id: G1KC29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C2 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

28377:rara
gene id: 28377:rara
uniprot id: A0A803T1B0
uniprot id: G1KAS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

28377:egfl6
gene id: 28377:egfl6
uniprot id: G1K9P9
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:crh
gene id: 28377:crh
uniprot id: G1KSW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

28377:cept1
gene id: 28377:cept1
uniprot id: A0A803SVS8
uniprot id: G1KCZ8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

28377:LOC100564196
gene id: 28377:LOC100564196
uniprot id: G1KWG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
messages: Membrane

28377:gas6
gene id: 28377:gas6
uniprot id: A0A803T8U3
uniprot id: A0A803TIR2
uniprot id: G1K8T5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:cd8a
gene id: 28377:cd8a
uniprot id: G1KL70
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28377:itga3
gene id: 28377:itga3
uniprot id: A0A803U0C7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:ccdc93
gene id: 28377:ccdc93
uniprot id: G1KA46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC93 family.
messages: Early endosome

28377:nmt2
gene id: 28377:nmt2
uniprot id: G1KSL0
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

28377:acot13
gene id: 28377:acot13
uniprot id: G1KAI0
names: Similarity
messages: Belongs to the thioesterase PaaI family.

28377:tlr7
gene id: 28377:tlr7
uniprot id: G1K9P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

28377:LOC100555069
gene id: 28377:LOC100555069
uniprot id: G1KMB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

28377:cacnb1
gene id: 28377:cacnb1
uniprot id: A0A803SM98
uniprot id: A0A803TH12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Membrane
messages: sarcolemma

28377:fam120b
gene id: 28377:fam120b
uniprot id: G1KB05
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

28377:LOC100567188
gene id: 28377:LOC100567188
uniprot id: R4GD93
names: Similarity
messages: Belongs to the actin family.

28377:ghsr
gene id: 28377:ghsr
uniprot id: G1KSJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine).

28377:ap1s3
gene id: 28377:ap1s3
uniprot id: G1KCY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

28377:LOC100567570
gene id: 28377:LOC100567570
uniprot id: A0A803T9I8
uniprot id: G1KGS4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28377:armc1
gene id: 28377:armc1
uniprot id: G1KT37
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

28377:LOC100552454
gene id: 28377:LOC100552454
uniprot id: G1KYQ0
names: Similarity
messages: Belongs to the peptidase M10A family.

28377:cmas
gene id: 28377:cmas
uniprot id: A0A803STF5
uniprot id: G1KTP0
names: Similarity
messages: Belongs to the CMP-NeuNAc synthase family.

28377:dock8
gene id: 28377:dock8
uniprot id: A0A803TZW6
uniprot id: G1KAF3
names: Similarity
messages: Belongs to the DOCK family.

28377:atp6v1g2
gene id: 28377:atp6v1g2
uniprot id: G1KLZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

28377:thra
gene id: 28377:thra
uniprot id: G1KBE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

28377:nmt1
gene id: 28377:nmt1
uniprot id: A0A803T143
uniprot id: G1KGM0
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

28377:rarg
gene id: 28377:rarg
uniprot id: A0A803SLV9
uniprot id: A0A803SU22
uniprot id: G1KFW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

28377:slc25a18
gene id: 28377:slc25a18
uniprot id: G1KM82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

28377:LOC100564372
gene id: 28377:LOC100564372
uniprot id: G1KIS3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28377:ankrd13d
gene id: 28377:ankrd13d
uniprot id: G1KH90
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

28377:capn13
gene id: 28377:capn13
uniprot id: G1KGI9
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:gab1
gene id: 28377:gab1
uniprot id: A0A803SWY0
uniprot id: A0A803T7T6
uniprot id: G1KBE7
names: Similarity
messages: Belongs to the GAB family.

28377:col18a1
gene id: 28377:col18a1
uniprot id: A0A803T999
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:dazap2
gene id: 28377:dazap2
uniprot id: G1KM01
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus speckle
messages: nuclear body

28377:nkiras2
gene id: 28377:nkiras2
uniprot id: A0A803T4N2
uniprot id: G1KTA9
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

28377:wnt1
gene id: 28377:wnt1
uniprot id: A0A803TJF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

28377:ubac2
gene id: 28377:ubac2
uniprot id: A0A803TN19
names: Subcellular Location Annotation
messages: Membrane

28377:LOC100554014
gene id: 28377:LOC100554014
uniprot id: G1K9A8
names: Similarity
messages: Belongs to the intermediate filament family.

28377:atxn1
gene id: 28377:atxn1
uniprot id: G1KCC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

28377:pdia6
gene id: 28377:pdia6
uniprot id: G1KN70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

28377:tram2
gene id: 28377:tram2
uniprot id: G1KDK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

28377:pxmp4
gene id: 28377:pxmp4
uniprot id: A0A803SLS7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Interacts with PEX19.
messages: Peroxisome membrane

28377:elf3
gene id: 28377:elf3
uniprot id: A0A803TFP0
uniprot id: G1KCK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

28377:hnrnpdl
gene id: 28377:hnrnpdl
uniprot id: G1KK24
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

28377:pgr
gene id: 28377:pgr
uniprot id: G1KP48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

28377:plk3
gene id: 28377:plk3
uniprot id: G1KRC9
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

28377:ppp3r1
gene id: 28377:ppp3r1
uniprot id: A0A803SNH9
uniprot id: A0A803SU11
uniprot id: A0A803TZD2
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

28377:tbc1d7
gene id: 28377:tbc1d7
uniprot id: G1KCQ7
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Vesicle

28377:ccnb1
gene id: 28377:ccnb1
uniprot id: G1KSK4
names: Similarity
messages: Belongs to the cyclin family.

28377:phf10
gene id: 28377:phf10
uniprot id: G1KEE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAYP family.
messages: Nucleus

28377:ndufb1
gene id: 28377:ndufb1
uniprot id: G1KX62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

28377:kiaa1147
gene id: 28377:kiaa1147
uniprot id: G1KL73
names: Similarity
messages: Belongs to the DENND11 family.

28377:gpr37l1
gene id: 28377:gpr37l1
uniprot id: A0A803T793
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28377:postn
gene id: 28377:postn
uniprot id: A0A803SYR2
uniprot id: A0A803TMA7
uniprot id: A0A803TQ92
uniprot id: A0A803TVY1
uniprot id: G1KU83
names: Subcellular Location Annotation
messages: extracellular matrix

28377:cdc20b
gene id: 28377:cdc20b
uniprot id: A0A803T7H5
uniprot id: A0A803TR89
uniprot id: G1KR39
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

28377:nfx1
gene id: 28377:nfx1
uniprot id: G1KAY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

28377:LOC100562739
gene id: 28377:LOC100562739
uniprot id: G1KL23
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

28377:LOC100558791
gene id: 28377:LOC100558791
uniprot id: G1KFN5
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Monomer.

28377:atp6ap2
gene id: 28377:atp6ap2
uniprot id: G1KPW9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

28377:vwc2
gene id: 28377:vwc2
uniprot id: G1KHG8
names: Subcellular Location Annotation
messages: Synapse

28377:LOC100565570
gene id: 28377:LOC100565570
uniprot id: G1KSR7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

28377:olfm4
gene id: 28377:olfm4
uniprot id: G1K8G3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:kcne1
gene id: 28377:kcne1
uniprot id: G1KDJ1
names: Similarity
messages: Belongs to the potassium channel KCNE family.

28377:rngtt
gene id: 28377:rngtt
uniprot id: G1KQB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
messages: In the C-terminal section; belongs to the eukaryotic GTase family.
messages: In the N-terminal section; belongs to the non-receptor class of the protein-tyrosine phosphatase family.
messages: Nucleus

28377:spic
gene id: 28377:spic
uniprot id: A0A803SW30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

28377:LOC103278031
gene id: 28377:LOC103278031
uniprot id: A0A803SZ65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Nucleus

28377:fam175b
gene id: 28377:fam175b
uniprot id: A0A803TYQ8
names: Subcellular Location Annotation
messages: Nucleus

28377:reep2
gene id: 28377:reep2
uniprot id: G1KGB1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:sh3bgrl2
gene id: 28377:sh3bgrl2
uniprot id: G1KTW0
names: Similarity
messages: Belongs to the SH3BGR family.

28377:bre
gene id: 28377:bre
uniprot id: G1KJ43
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BABAM2 family.
messages: Component of the ARISC complex. Component of the BRCA1-A complex. Component of the BRISC complex. Binds polyubiquitin.
messages: Contains 2 ubiquitin-conjugating enzyme family-like (UEV-like) regions. These regions lack the critical Cys residues required for ubiquitination but retain the ability to bind ubiquitin.
messages: Cytoplasm
messages: May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway.
messages: Nucleus

28377:prkaa2
gene id: 28377:prkaa2
uniprot id: G1KFT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: Cytoplasm

28377:ND4L
gene id: 28377:ND4L
uniprot id: B3GSZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
messages: Membrane
messages: Mitochondrion inner membrane

28377:tdp1
gene id: 28377:tdp1
uniprot id: A0A803SNZ7
uniprot id: G1KQ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

28377:adipor2
gene id: 28377:adipor2
uniprot id: G1K856
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

28377:krt23
gene id: 28377:krt23
uniprot id: R4GBD3
names: Similarity
messages: Belongs to the intermediate filament family.

28377:cep19
gene id: 28377:cep19
uniprot id: G1KSD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body
messages: spindle pole

28377:LOC100566354
gene id: 28377:LOC100566354
uniprot id: R4GCB7
names: Subcellular Location Annotation
messages: Membrane

28377:pgs1
gene id: 28377:pgs1
uniprot id: G1KSY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

28377:zpbp
gene id: 28377:zpbp
uniprot id: G1KHI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zona pellucida-binding protein Sp38 family.
messages: Secreted

28377:fam110c
gene id: 28377:fam110c
uniprot id: G1KDY2
names: Similarity
messages: Belongs to the FAM110 family.

28377:slc39a6
gene id: 28377:slc39a6
uniprot id: G1K9Y6
names: Subcellular Location Annotation
messages: Membrane

28377:sar1a
gene id: 28377:sar1a
uniprot id: G1K9I8
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

28377:pacsin1
gene id: 28377:pacsin1
uniprot id: G1KRR6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytosol
messages: ruffle membrane
messages: synaptosome

28377:nup50
gene id: 28377:nup50
uniprot id: G1KRG1
names: Subcellular Location Annotation
messages: nuclear pore complex

28377:actrt3
gene id: 28377:actrt3
uniprot id: G1KRF3
names: Similarity
messages: Belongs to the actin family.

28377:ngfr
gene id: 28377:ngfr
uniprot id: G1KD91
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:naxd
gene id: 28377:naxd
uniprot id: G1KF06
names: Function
names: Similarity
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.

28377:api5
gene id: 28377:api5
uniprot id: G1KRG2
names: Similarity
messages: Belongs to the API5 family.

28377:itpkc
gene id: 28377:itpkc
uniprot id: H9GJZ6
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

28377:slc43a3
gene id: 28377:slc43a3
uniprot id: A0A803T9S8
uniprot id: G1KGE5
names: Subcellular Location Annotation
messages: Membrane

28377:kiaa1324
gene id: 28377:kiaa1324
uniprot id: G1KJW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

28377:smarcd2
gene id: 28377:smarcd2
uniprot id: G1KUI3
names: Similarity
messages: Belongs to the SMARCD family.

28377:eme1
gene id: 28377:eme1
uniprot id: G1KDU1
names: Similarity
messages: Belongs to the EME1/MMS4 family.

28377:amhr2
gene id: 28377:amhr2
uniprot id: A0A803TUX2
uniprot id: G1K8P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Secreted

28377:oxct1
gene id: 28377:oxct1
uniprot id: G1KKA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
messages: Mitochondrion

28377:acadsb
gene id: 28377:acadsb
uniprot id: G1KU01
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

28377:il6st
gene id: 28377:il6st
uniprot id: G1KQG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

28377:arhgdia
gene id: 28377:arhgdia
uniprot id: G1KK92
names: Similarity
messages: Belongs to the Rho GDI family.

28377:cct8
gene id: 28377:cct8
uniprot id: A0A803T8A4
uniprot id: G1KA10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: cilium basal body

28377:alg5
gene id: 28377:alg5
uniprot id: G1KU96
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

28377:coq10a
gene id: 28377:coq10a
uniprot id: G1KGQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

28377:clvs1
gene id: 28377:clvs1
uniprot id: G1KEX3
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network membrane

28377:syngr2
gene id: 28377:syngr2
uniprot id: G1KT11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

28377:palmd
gene id: 28377:palmd
uniprot id: G1KCD7
names: Similarity
messages: Belongs to the paralemmin family.

28377:crhbp
gene id: 28377:crhbp
uniprot id: G1KH88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

28377:LOC100556974
gene id: 28377:LOC100556974
uniprot id: G1KTP2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

28377:bcap31
gene id: 28377:bcap31
uniprot id: G1KI14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

28377:tmem150c
gene id: 28377:tmem150c
uniprot id: A0A803U1L5
names: Subcellular Location Annotation
messages: Membrane

28377:aldob
gene id: 28377:aldob
uniprot id: A0A803SNH7
uniprot id: G1KTX7
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

28377:mterf1
gene id: 28377:mterf1
uniprot id: G1KRK0
names: Similarity
messages: Belongs to the mTERF family.

28377:klc4
gene id: 28377:klc4
uniprot id: G1KDL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

28377:aldh1l2
gene id: 28377:aldh1l2
uniprot id: G1KRQ0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

28377:cenph
gene id: 28377:cenph
uniprot id: G1KSK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-H/MCM16 family.
messages: Nucleus
messages: kinetochore

28377:glo1
gene id: 28377:glo1
uniprot id: A0A803TV79
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

28377:sec61a1
gene id: 28377:sec61a1
uniprot id: A0A803T481
uniprot id: G1KGE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:ppargc1b
gene id: 28377:ppargc1b
uniprot id: G1KRI7
names: Subcellular Location Annotation
messages: Nucleus

28377:nlgn4x
gene id: 28377:nlgn4x
uniprot id: D2X2I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

28377:gmppa
gene id: 28377:gmppa
uniprot id: A0A803SV96
uniprot id: G1KPI0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

28377:carnmt1
gene id: 28377:carnmt1
uniprot id: R4GAZ3
names: Similarity
messages: Belongs to the carnosine N-methyltransferase family.

28377:c3hxorf36
gene id: 28377:c3hxorf36
uniprot id: G1KUG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

28377:yif1b
gene id: 28377:yif1b
uniprot id: H9G8A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

28377:scgn
gene id: 28377:scgn
uniprot id: G1K9J9
names: Subcellular Location Annotation
messages: Cytoplasm

28377:uba6
gene id: 28377:uba6
uniprot id: G1KNA2
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

28377:slc25a20
gene id: 28377:slc25a20
uniprot id: G1KLX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

28377:psen1
gene id: 28377:psen1
uniprot id: A0A803SNS1
uniprot id: G1KSC0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Cytoplasmic granule
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: Synapse
messages: The PAL motif is required for normal active site conformation.
messages: axon
messages: neuron projection

28377:psma2
gene id: 28377:psma2
uniprot id: G1KU31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Nucleus

28377:lca5
gene id: 28377:lca5
uniprot id: G1KCX4
names: Similarity
messages: Belongs to the LCA5 family.

28377:cfi
gene id: 28377:cfi
uniprot id: G1KJP9
names: Caution
names: Similarity
messages: Belongs to the peptidase S1 family. Snake venom subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:mmp24
gene id: 28377:mmp24
uniprot id: G1KE46
names: Similarity
messages: Belongs to the peptidase M10A family.

28377:LOC103278592
gene id: 28377:LOC103278592
uniprot id: A0A803U1A2
names: Similarity
messages: Belongs to the CD225/Dispanin family.

28377:acta1
gene id: 28377:acta1
uniprot id: G1K932
uniprot id: L7MZF2
names: Similarity
messages: Belongs to the actin family.

28377:csrnp1
gene id: 28377:csrnp1
uniprot id: G1KJA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

28377:eif2b2
gene id: 28377:eif2b2
uniprot id: G1KT52
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

28377:aga
gene id: 28377:aga
uniprot id: G1KEX1
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

28377:aldh9a1
gene id: 28377:aldh9a1
uniprot id: G1KNT0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

28377:mdfi
gene id: 28377:mdfi
uniprot id: G1KAZ3
names: Similarity
messages: Belongs to the MDFI family.

28377:cry1
gene id: 28377:cry1
uniprot id: A0A803STD7
uniprot id: G1KQX0
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

28377:cpq
gene id: 28377:cpq
uniprot id: G1KCR8
names: Subcellular Location Annotation
names: Subunit
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. The monomeric form is inactive while the homodimer is active.
messages: Lysosome
messages: Secreted

28377:smug1
gene id: 28377:smug1
uniprot id: A0A803SQG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. SMUG1 family.
messages: Nucleus

28377:LOC100562413
gene id: 28377:LOC100562413
uniprot id: G1KAF8
names: Similarity
messages: Belongs to the NDK family.

28377:gpr35
gene id: 28377:gpr35
uniprot id: G1KX02
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:alx1
gene id: 28377:alx1
uniprot id: G1KKV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

28377:slc33a1
gene id: 28377:slc33a1
uniprot id: G1K8J3
names: Subcellular Location Annotation
messages: Membrane

28377:kcnq2
gene id: 28377:kcnq2
uniprot id: A0A803TM57
uniprot id: G1KEV7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28377:LOC100566739
gene id: 28377:LOC100566739
uniprot id: G1KAY0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

28377:tbx20
gene id: 28377:tbx20
uniprot id: G1KGN2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

28377:slc12a2
gene id: 28377:slc12a2
uniprot id: A0A803SSP9
uniprot id: G1KAX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

28377:glra2
gene id: 28377:glra2
uniprot id: G1KKB4
uniprot id: H9GFL1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

28377:LOC100554797
gene id: 28377:LOC100554797
uniprot id: G1KZB8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:ppil6
gene id: 28377:ppil6
uniprot id: G1KF63
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

28377:trpc1
gene id: 28377:trpc1
uniprot id: G1KD53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
messages: Membrane
messages: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

28377:sfrp2
gene id: 28377:sfrp2
uniprot id: G1KRK6
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:tlr3
gene id: 28377:tlr3
uniprot id: G1K9T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

28377:ispd
gene id: 28377:ispd
uniprot id: G1KMW3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Homodimer.
messages: cytosol

28377:nr3c2
gene id: 28377:nr3c2
uniprot id: A0A803TKW1
names: Subcellular Location Annotation
messages: Nucleus

28377:nfs1
gene id: 28377:nfs1
uniprot id: G1KFC2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

28377:pdlim3
gene id: 28377:pdlim3
uniprot id: G1KA73
names: Subcellular Location Annotation
messages: Z line

28377:abi1
gene id: 28377:abi1
uniprot id: A0A803SQC5
uniprot id: A0A803T6L1
uniprot id: G1KHE5
uniprot id: G1KUV5
names: Similarity
messages: Belongs to the ABI family.

28377:cstf3
gene id: 28377:cstf3
uniprot id: G1KBE9
names: Subcellular Location Annotation
messages: Nucleus

28377:chrm4
gene id: 28377:chrm4
uniprot id: G1KCJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

28377:ltn1
gene id: 28377:ltn1
uniprot id: G1K9J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

28377:LOC100553704
gene id: 28377:LOC100553704
uniprot id: A0A803TC86
names: Subcellular Location Annotation
messages: Membrane

28377:LOC100564631
gene id: 28377:LOC100564631
uniprot id: A0A803TW74
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

28377:sema3a
gene id: 28377:sema3a
uniprot id: G1KSF9
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:LOC100566415
gene id: 28377:LOC100566415
uniprot id: G1KLQ7
names: Similarity
messages: Belongs to the ohanin/vespryn family.

28377:cwf19l2
gene id: 28377:cwf19l2
uniprot id: A0A803TZM6
uniprot id: G1KKR3
names: Similarity
messages: Belongs to the CWF19 family.

28377:LOC100565219
gene id: 28377:LOC100565219
uniprot id: A0A803SY69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GST superfamily. Pi family.
messages: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Nucleus

28377:ovch1
gene id: 28377:ovch1
uniprot id: G1K871
names: Caution
names: Similarity
messages: Belongs to the peptidase S1 family. Snake venom subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:ackr4
gene id: 28377:ackr4
uniprot id: G1K8T0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:LOC100554740
gene id: 28377:LOC100554740
uniprot id: G1KEP9
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

28377:agap2
gene id: 28377:agap2
uniprot id: A0A803T124
uniprot id: G1KNR8
names: Similarity
messages: Belongs to the centaurin gamma-like family.

28377:prdx1
gene id: 28377:prdx1
uniprot id: G1KQP3
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

28377:npy1r
gene id: 28377:npy1r
uniprot id: G1KDK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:vwde
gene id: 28377:vwde
uniprot id: G1KV13
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:prr5l
gene id: 28377:prr5l
uniprot id: G1KDP1
names: Similarity
messages: Belongs to the PROTOR family.

28377:serp1
gene id: 28377:serp1
uniprot id: A0A803SVU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

28377:il17b
gene id: 28377:il17b
uniprot id: G1KRD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

28377:tmem132c
gene id: 28377:tmem132c
uniprot id: A0A803TPS4
uniprot id: H9GL19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

28377:ca10
gene id: 28377:ca10
uniprot id: G1KTU6
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

28377:cntnap4
gene id: 28377:cntnap4
uniprot id: A0A803THJ2
uniprot id: G1KSM0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:tmem200c
gene id: 28377:tmem200c
uniprot id: G1KJF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

28377:c4h1orf123
gene id: 28377:c4h1orf123
uniprot id: G1KI50
names: Similarity
messages: Belongs to the UPF0587 family.

28377:nts
gene id: 28377:nts
uniprot id: G1KKX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurotensin family.
messages: Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
messages: Secreted
messages: Vesicle
messages: secretory vesicle

28377:htt
gene id: 28377:htt
uniprot id: A0A803SPD1
uniprot id: G1KE86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the huntingtin family.
messages: Cytoplasm
messages: May play a role in microtubule-mediated transport or vesicle function.
messages: Nucleus

28377:hbegf
gene id: 28377:hbegf
uniprot id: A0A803SZA9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:gsto1
gene id: 28377:gsto1
uniprot id: G1KDR7
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

28377:rnf114
gene id: 28377:rnf114
uniprot id: G1KRD0
names: Subunit
messages: Interacts with XAF1, the interaction increases XAF1 stability and proapoptotic effects, and may regulate IFN signaling.

28377:chpf
gene id: 28377:chpf
uniprot id: G1KPM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

28377:lsm12
gene id: 28377:lsm12
uniprot id: A0A803TRN5
names: Similarity
messages: Belongs to the LSM12 family.

28377:kcnq3
gene id: 28377:kcnq3
uniprot id: A0A803TYN1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28377:LOC100563155
gene id: 28377:LOC100563155
uniprot id: G1KNS4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:phb
gene id: 28377:phb
uniprot id: G1KD73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

28377:fyn
gene id: 28377:fyn
uniprot id: A0A803T3N6
uniprot id: A0A803TM61
uniprot id: G1KLG4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

28377:ccnt1
gene id: 28377:ccnt1
uniprot id: G1KI49
names: Similarity
messages: Belongs to the cyclin family. Cyclin C subfamily.

28377:ptdss2
gene id: 28377:ptdss2
uniprot id: G1KNZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:LOC100565290
gene id: 28377:LOC100565290
uniprot id: A0A803SYQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

28377:cpt2
gene id: 28377:cpt2
uniprot id: G1KI37
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

28377:scp2
gene id: 28377:scp2
uniprot id: G1KHY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Cytoplasm
messages: Mitochondrion
messages: Peroxisome

28377:c3h11orf73
gene id: 28377:c3h11orf73
uniprot id: A0A803TJ45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
messages: Belongs to the OPI10 family.
messages: Cytoplasm
messages: Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.
messages: Nucleus
messages: cytosol

28377:gja8
gene id: 28377:gja8
uniprot id: G1KPB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

28377:mfsd6
gene id: 28377:mfsd6
uniprot id: A0A803TA43
uniprot id: G1K8S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

28377:wisp1
gene id: 28377:wisp1
uniprot id: G1KLD0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:grm5
gene id: 28377:grm5
uniprot id: A0A803TND1
uniprot id: G1KQQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

28377:gpn3
gene id: 28377:gpn3
uniprot id: H9GMW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

28377:slc44a2
gene id: 28377:slc44a2
uniprot id: A0A803TA58
uniprot id: G1KRQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

28377:crhr1
gene id: 28377:crhr1
uniprot id: G1KUI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

28377:arpc3
gene id: 28377:arpc3
uniprot id: H9GMW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

28377:cblb
gene id: 28377:cblb
uniprot id: A0A803T3M5
uniprot id: G1KFF7
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

28377:fam135a
gene id: 28377:fam135a
uniprot id: G1KHT7
names: Similarity
messages: Belongs to the FAM135 family.

28377:pias2
gene id: 28377:pias2
uniprot id: G1KM13
names: Similarity
messages: Belongs to the PIAS family.

28377:chga
gene id: 28377:chga
uniprot id: G1KI85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

28377:rnmt
gene id: 28377:rnmt
uniprot id: R4GB35
names: Similarity
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.

28377:pir
gene id: 28377:pir
uniprot id: G1KM88
names: Similarity
messages: Belongs to the pirin family.

28377:LOC103277827
gene id: 28377:LOC103277827
uniprot id: A0A803T3R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

28377:abcc8
gene id: 28377:abcc8
uniprot id: G1K878
names: Subunit
messages: Interacts with KCNJ11.

28377:LOC103277774
gene id: 28377:LOC103277774
uniprot id: A0A803THB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

28377:chmp6
gene id: 28377:chmp6
uniprot id: G1KR78
names: Similarity
messages: Belongs to the SNF7 family.

28377:ccdc181
gene id: 28377:ccdc181
uniprot id: G1KK94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC181 family.
messages: Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
messages: cytoskeleton
messages: flagellum

28377:zc2hc1c
gene id: 28377:zc2hc1c
uniprot id: G1KT67
names: Similarity
messages: Belongs to the ZC2HC1 family.

28377:sgtb
gene id: 28377:sgtb
uniprot id: G1KRT3
names: Similarity
messages: Belongs to the SGT family.

28377:slc30a8
gene id: 28377:slc30a8
uniprot id: G1KKM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Cell membrane
messages: Membrane
messages: secretory vesicle membrane

28377:dtd1
gene id: 28377:dtd1
uniprot id: G1KG77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

28377:prcp
gene id: 28377:prcp
uniprot id: G1K911
names: Similarity
messages: Belongs to the peptidase S28 family.

28377:ddx1
gene id: 28377:ddx1
uniprot id: G1KL19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX1 subfamily.
messages: Cytoplasmic granule

28377:uros
gene id: 28377:uros
uniprot id: G1K8Y2
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

28377:brinp2
gene id: 28377:brinp2
uniprot id: G1KPX2
names: Similarity
messages: Belongs to the BRINP family.

28377:tmtc4
gene id: 28377:tmtc4
uniprot id: G1KBZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

28377:add3
gene id: 28377:add3
uniprot id: A0A803T5Y7
uniprot id: G1KF70
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

28377:LOC100559872
gene id: 28377:LOC100559872
uniprot id: G1KGC9
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

28377:atp5b
gene id: 28377:atp5b
uniprot id: G1KT22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

28377:sfmbt1
gene id: 28377:sfmbt1
uniprot id: G1KHN7
names: Subcellular Location Annotation
messages: Nucleus

28377:terf1
gene id: 28377:terf1
uniprot id: G1KPX9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
messages: Homodimer.
messages: Nucleus

28377:nkain4
gene id: 28377:nkain4
uniprot id: G1KXT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

28377:rftn1
gene id: 28377:rftn1
uniprot id: G1KH26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

28377:cldn10
gene id: 28377:cldn10
uniprot id: G1KA53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

28377:tmpo
gene id: 28377:tmpo
uniprot id: A0A803TF01
uniprot id: A0A803TYP9
uniprot id: G1KNK2
names: Similarity
messages: Belongs to the LEM family.

28377:LOC100555455
gene id: 28377:LOC100555455
uniprot id: G1KGN7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

28377:htr4
gene id: 28377:htr4
uniprot id: A0A803SS49
uniprot id: A0A803TJX6
uniprot id: G1KRL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

28377:foxg1
gene id: 28377:foxg1
uniprot id: G1KS18
names: Subcellular Location Annotation
messages: Nucleus

28377:ppm1k
gene id: 28377:ppm1k
uniprot id: G1KMY3
names: Similarity
messages: Belongs to the PP2C family.

28377:dcn
gene id: 28377:dcn
uniprot id: G1KM87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: Binds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN.
messages: May affect the rate of fibrils formation.
messages: extracellular matrix

28377:LOC100565773
gene id: 28377:LOC100565773
uniprot id: A0A803T7V3
names: Subcellular Location Annotation
messages: Membrane

28377:fam198b
gene id: 28377:fam198b
uniprot id: G1KST9
names: Similarity
messages: Belongs to the GASK family.

28377:mlh1
gene id: 28377:mlh1
uniprot id: G1KJR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

28377:ednrb
gene id: 28377:ednrb
uniprot id: A0A803T6S5
uniprot id: G1KSC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:LOC103278482
gene id: 28377:LOC103278482
uniprot id: A0A803T8M9
uniprot id: A0A803TAS9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:chdh
gene id: 28377:chdh
uniprot id: G1KLE3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.

28377:dmap1
gene id: 28377:dmap1
uniprot id: G1KQ81
names: Subcellular Location Annotation
messages: Nucleus

28377:prr15l
gene id: 28377:prr15l
uniprot id: G1KFP4
names: Similarity
messages: Belongs to the PRR15 family.

28377:smpx
gene id: 28377:smpx
uniprot id: G1KSZ9
names: Function
names: Similarity
messages: Belongs to the SMPX family.
messages: Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair.

28377:hoxc5
gene id: 28377:hoxc5
uniprot id: G1KKN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

28377:ppp1cb
gene id: 28377:ppp1cb
uniprot id: G1KIW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cytoplasm

28377:tspan8
gene id: 28377:tspan8
uniprot id: G1KG83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

28377:yars2
gene id: 28377:yars2
uniprot id: G1KM69
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

28377:dusp10
gene id: 28377:dusp10
uniprot id: G1KA87
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

28377:hal
gene id: 28377:hal
uniprot id: G1KPE2
names: Similarity
messages: Belongs to the PAL/histidase family.

28377:mrps14
gene id: 28377:mrps14
uniprot id: A0A803TRZ3
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

28377:neu1
gene id: 28377:neu1
uniprot id: G1KLY3
uniprot id: K0PUN9
names: Miscellaneous
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.

28377:rbm22
gene id: 28377:rbm22
uniprot id: G1KQA8
names: Similarity
messages: Belongs to the SLT11 family.

28377:etv5
gene id: 28377:etv5
uniprot id: G1KHF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

28377:clgn
gene id: 28377:clgn
uniprot id: G1KAL5
names: Similarity
messages: Belongs to the calreticulin family.

28377:naa35
gene id: 28377:naa35
uniprot id: G1K8P6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MAK10 family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
messages: Cytoplasm

28377:enah
gene id: 28377:enah
uniprot id: A0A803TNH2
uniprot id: G1KEM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: cytoskeleton

28377:ccni
gene id: 28377:ccni
uniprot id: G1KM05
names: Similarity
messages: Belongs to the cyclin family.

28377:c5h16orf70
gene id: 28377:c5h16orf70
uniprot id: G1KND5
names: Similarity
messages: Belongs to the PHAF1 family.

28377:triqk
gene id: 28377:triqk
uniprot id: G1KBV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIQK family.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:qsox1
gene id: 28377:qsox1
uniprot id: G1K901
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

28377:snrpc
gene id: 28377:snrpc
uniprot id: A0A803TGH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

28377:sf3b5
gene id: 28377:sf3b5
uniprot id: G1KH75
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

28377:gbe1
gene id: 28377:gbe1
uniprot id: A0A803TSP8
uniprot id: G1KAH1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

28377:dmrt3
gene id: 28377:dmrt3
uniprot id: G1KAM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

28377:LOC100566795
gene id: 28377:LOC100566795
uniprot id: G1KLM2
names: Similarity
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.

28377:add1
gene id: 28377:add1
uniprot id: A0A803TMD0
uniprot id: G1KDT9
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

28377:slc25a32
gene id: 28377:slc25a32
uniprot id: G1KIX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

28377:sh3bp4
gene id: 28377:sh3bp4
uniprot id: G1KJN7
names: Subcellular Location Annotation
messages: Nucleus
messages: Vesicle
messages: clathrin-coated pit
messages: clathrin-coated vesicle

28377:per2
gene id: 28377:per2
uniprot id: G1KB77
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

28377:ube2n
gene id: 28377:ube2n
uniprot id: G1KMH7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

28377:galnt7
gene id: 28377:galnt7
uniprot id: A0A803T275
uniprot id: G1KE43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

28377:slc1a4
gene id: 28377:slc1a4
uniprot id: G1K9W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

28377:LOC100555783
gene id: 28377:LOC100555783
uniprot id: G1KFM8
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:LOC100560613
gene id: 28377:LOC100560613
uniprot id: G1KCM4
names: Similarity
messages: Belongs to the serpin family.

28377:LOC103278072
gene id: 28377:LOC103278072
uniprot id: A0A803TBZ2
uniprot id: R4GBN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Cell membrane
messages: Membrane
messages: Secreted
messages: The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.

28377:sostdc1
gene id: 28377:sostdc1
uniprot id: A0A803T8H7
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:LOC100551649
gene id: 28377:LOC100551649
uniprot id: A0A803SS02
names: Similarity
messages: Belongs to the CD225/Dispanin family.

28377:ckmt2
gene id: 28377:ckmt2
uniprot id: G1KKN7
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

28377:ccdc167
gene id: 28377:ccdc167
uniprot id: A0A803SVT8
names: Subcellular Location Annotation
messages: Membrane

28377:tmco3
gene id: 28377:tmco3
uniprot id: A0A803TFY0
uniprot id: G1K8H0
names: Subcellular Location Annotation
messages: Membrane

28377:cdc14b
gene id: 28377:cdc14b
uniprot id: A0A803T948
uniprot id: A0A803TA17
uniprot id: A0A803TK81
uniprot id: A0A803U058
uniprot id: G1KVB1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

28377:slc7a6
gene id: 28377:slc7a6
uniprot id: H9GGF1
names: Subcellular Location Annotation
messages: Membrane

28377:tp53inp2
gene id: 28377:tp53inp2
uniprot id: A0A803SME6
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

28377:skil
gene id: 28377:skil
uniprot id: G1KRY8
names: Similarity
messages: Belongs to the SKI family.

28377:ttc4
gene id: 28377:ttc4
uniprot id: G1KQ35
names: Similarity
messages: Belongs to the TTC4 family.

28377:mcm10
gene id: 28377:mcm10
uniprot id: G1K9B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

28377:jph1
gene id: 28377:jph1
uniprot id: G1KN76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

28377:pla2g12a
gene id: 28377:pla2g12a
uniprot id: A0A803TGE4
names: Subcellular Location Annotation
messages: Secreted

28377:gpr75
gene id: 28377:gpr75
uniprot id: G1KM77
names: Similarity
messages: Belongs to the BLM10 family.

28377:arid1b
gene id: 28377:arid1b
uniprot id: A0A803SL05
uniprot id: A0A803TRD5
uniprot id: A0A803TU99
uniprot id: G1KDQ1
names: Subcellular Location Annotation
messages: Nucleus

28377:dynlt3
gene id: 28377:dynlt3
uniprot id: A0A803SML4
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

28377:LOC100552765
gene id: 28377:LOC100552765
uniprot id: R4GCL6
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

28377:srd5a3
gene id: 28377:srd5a3
uniprot id: G1KJ34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Also able to convert testosterone (T) into 5-alpha-dihydrotestosterone (DHT).
messages: Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism.

28377:mrps18c
gene id: 28377:mrps18c
uniprot id: G1KKN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Mitochondrion

28377:aste1
gene id: 28377:aste1
uniprot id: G1K9T1
names: Similarity
messages: Belongs to the asteroid family.

28377:kcnj15
gene id: 28377:kcnj15
uniprot id: A0A803TU69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

28377:memo1
gene id: 28377:memo1
uniprot id: A0A803T1B3
uniprot id: G1K8P2
names: Similarity
messages: Belongs to the MEMO1 family.

28377:ldlrad3
gene id: 28377:ldlrad3
uniprot id: G1KDP6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:LOC100568046
gene id: 28377:LOC100568046
uniprot id: L7MZN3
names: Similarity
messages: Belongs to the TCAF family.

28377:ing1
gene id: 28377:ing1
uniprot id: G1KF27
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

28377:cdc42se2
gene id: 28377:cdc42se2
uniprot id: G1K9D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

28377:pyy
gene id: 28377:pyy
uniprot id: G1KDC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

28377:wnt5a
gene id: 28377:wnt5a
uniprot id: G1KTY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

28377:ltbp2
gene id: 28377:ltbp2
uniprot id: A0A803TKY9
uniprot id: G1KSS0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

28377:crhr2
gene id: 28377:crhr2
uniprot id: A0A803TPD2
uniprot id: G1KEL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

28377:fam198a
gene id: 28377:fam198a
uniprot id: G1KBI0
names: Similarity
messages: Belongs to the GASK family.

28377:ppp2r5a
gene id: 28377:ppp2r5a
uniprot id: R4GAU5
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

28377:sbf2
gene id: 28377:sbf2
uniprot id: A0A803TNQ2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

28377:lin52
gene id: 28377:lin52
uniprot id: A0A803SQT3
uniprot id: G1KSG5
names: Similarity
messages: Belongs to the lin-52 family.

28377:cndp2
gene id: 28377:cndp2
uniprot id: G1KC62
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

28377:tfcp2
gene id: 28377:tfcp2
uniprot id: G1KM92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

28377:hps5
gene id: 28377:hps5
uniprot id: A0A803SKL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPS5 family.
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: cytosol

28377:pcbd1
gene id: 28377:pcbd1
uniprot id: G1KI78
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

28377:mis18a
gene id: 28377:mis18a
uniprot id: G1KB64
names: Function
names: Subcellular Location Annotation
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

28377:fev
gene id: 28377:fev
uniprot id: A0A803TP37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

28377:dazl
gene id: 28377:dazl
uniprot id: G1KH34
names: Subcellular Location Annotation
messages: Cytoplasm

28377:LOC100556452
gene id: 28377:LOC100556452
uniprot id: R4GBW3
names: Similarity
messages: Belongs to the cytochrome P450 family.

28377:stab1
gene id: 28377:stab1
uniprot id: G1KG37
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

28377:rgmb
gene id: 28377:rgmb
uniprot id: G1KLJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

28377:aars2
gene id: 28377:aars2
uniprot id: G1KQ51
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

28377:LOC100556586
gene id: 28377:LOC100556586
uniprot id: G1KTJ5
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

28377:nim1k
gene id: 28377:nim1k
uniprot id: G1KKG7
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:hrh1
gene id: 28377:hrh1
uniprot id: G1KJV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:fam46a
gene id: 28377:fam46a
uniprot id: A0A803SQZ3
names: Similarity
messages: Belongs to the TENT family.

28377:dock7
gene id: 28377:dock7
uniprot id: A0A803SLW6
uniprot id: G1KHC5
names: Similarity
messages: Belongs to the DOCK family.

28377:pycr1
gene id: 28377:pycr1
uniprot id: G1KK19
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

28377:lect1
gene id: 28377:lect1
uniprot id: G1K8K4
names: Similarity
messages: Belongs to the chondromodulin-1 family.

28377:LOC100558055
gene id: 28377:LOC100558055
uniprot id: G1K8M7
uniprot id: R4GA71
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28377:rgs14
gene id: 28377:rgs14
uniprot id: G1KFE4
names: Subcellular Location Annotation
messages: dendrite

28377:timp3
gene id: 28377:timp3
uniprot id: A0A803SXP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: extracellular matrix

28377:adcy1
gene id: 28377:adcy1
uniprot id: G1KHB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

28377:cep70
gene id: 28377:cep70
uniprot id: G1KJ57
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Directly interacts with tubulin-gamma; this interaction determines centrosomal localization.
messages: Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.
messages: centrosome

28377:sigirr
gene id: 28377:sigirr
uniprot id: G1KNW6
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

28377:gmpr
gene id: 28377:gmpr
uniprot id: G1KCB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

28377:hsd17b6
gene id: 28377:hsd17b6
uniprot id: A0A803TSY7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28377:fam188b
gene id: 28377:fam188b
uniprot id: G1KEN1
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

28377:shh
gene id: 28377:shh
uniprot id: A0A803SKN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

28377:nmd3
gene id: 28377:nmd3
uniprot id: G1KGH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

28377:soga1
gene id: 28377:soga1
uniprot id: A0A803TZX2
names: Similarity
messages: Belongs to the SOGA family.

28377:foxp1
gene id: 28377:foxp1
uniprot id: G1KPA1
uniprot id: R4GBW0
names: Subcellular Location Annotation
messages: Nucleus

28377:ccdc103
gene id: 28377:ccdc103
uniprot id: G1KGU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC103/PR46b family.
messages: Cytoplasm
messages: Dynein-attachment factor required for cilia motility.
messages: Homodimer.
messages: flagellum

28377:ndufs4
gene id: 28377:ndufs4
uniprot id: G1KR79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mitochondrion inner membrane

28377:ND1
gene id: 28377:ND1
uniprot id: B3GSZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

28377:gngt2
gene id: 28377:gngt2
uniprot id: A0A803SZW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

28377:rbm5
gene id: 28377:rbm5
uniprot id: G1KI28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBM5/RBM10 family.
messages: Nucleus

28377:LOC100554045
gene id: 28377:LOC100554045
uniprot id: G1KL57
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:jun
gene id: 28377:jun
uniprot id: G1KG27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

28377:stk38
gene id: 28377:stk38
uniprot id: G1KSU7
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:nipal2
gene id: 28377:nipal2
uniprot id: G1KS65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

28377:dpf1
gene id: 28377:dpf1
uniprot id: H9GJW0
names: Similarity
messages: Belongs to the requiem/DPF family.

28377:gfm1
gene id: 28377:gfm1
uniprot id: G1KFW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
messages: Mitochondrion

28377:otc
gene id: 28377:otc
uniprot id: G1KQ60
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
messages: Homotrimer.

28377:LOC100560578
gene id: 28377:LOC100560578
uniprot id: G1KDV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

28377:rnaset2
gene id: 28377:rnaset2
uniprot id: G1KK73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Lysosome lumen

28377:tgfbr2
gene id: 28377:tgfbr2
uniprot id: G1KPQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: Membrane raft
messages: Secreted

28377:ebf3
gene id: 28377:ebf3
uniprot id: G1KI56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

28377:adprm
gene id: 28377:adprm
uniprot id: G1KTX6
names: Similarity
names: Subunit
messages: Belongs to the ADPRibase-Mn family.
messages: Monomer.

28377:nsun2
gene id: 28377:nsun2
uniprot id: G1K8Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: extracellular exosome

28377:ptprb
gene id: 28377:ptprb
uniprot id: A0A803TW57
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

28377:fn3krp
gene id: 28377:fn3krp
uniprot id: G1KTU8
names: Similarity
messages: Belongs to the fructosamine kinase family.

28377:phf5a
gene id: 28377:phf5a
uniprot id: G1KD50
names: Similarity
messages: Belongs to the PHF5 family.

28377:pon2
gene id: 28377:pon2
uniprot id: G1KPD0
names: Cofactor
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.

28377:LOC103278612
gene id: 28377:LOC103278612
uniprot id: G1KMY1
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: Membrane raft
messages: Secreted

28377:ebag9
gene id: 28377:ebag9
uniprot id: G1KAT9
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

28377:kiaa1429
gene id: 28377:kiaa1429
uniprot id: G1KC69
names: Similarity
messages: Belongs to the vir family.

28377:itpr3
gene id: 28377:itpr3
uniprot id: G1KSL8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

28377:ssh3
gene id: 28377:ssh3
uniprot id: G1KHA2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

28377:stc2
gene id: 28377:stc2
uniprot id: A0A803TK18
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

28377:adam11
gene id: 28377:adam11
uniprot id: A0A803TD60
uniprot id: G1KMP1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:smad2
gene id: 28377:smad2
uniprot id: A0A803SMT4
uniprot id: G1KUM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

28377:gfm2
gene id: 28377:gfm2
uniprot id: G1KIH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

28377:cel
gene id: 28377:cel
uniprot id: A0A803TGI9
uniprot id: G1KDB8
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

28377:atp8a1
gene id: 28377:atp8a1
uniprot id: G1KGP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

28377:ctbp2
gene id: 28377:ctbp2
uniprot id: A0A803SWG4
uniprot id: A0A803TNR1
uniprot id: G1KQ30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

28377:sugt1
gene id: 28377:sugt1
uniprot id: G1K8M8
names: Similarity
messages: Belongs to the SGT1 family.

28377:ccno
gene id: 28377:ccno
uniprot id: G1KR21
names: Similarity
messages: Belongs to the cyclin family.

28377:clpp
gene id: 28377:clpp
uniprot id: G1KRA1
names: Similarity
messages: Belongs to the peptidase S14 family.

28377:LOC100560702
gene id: 28377:LOC100560702
uniprot id: G1KQE7
names: Similarity
messages: Belongs to the JAKMIP family.

28377:wdpcp
gene id: 28377:wdpcp
uniprot id: G1KEQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat fritz family.
messages: Cell membrane
messages: Membrane
messages: cilium axoneme

28377:pfn3
gene id: 28377:pfn3
uniprot id: G1KA02
names: Similarity
messages: Belongs to the profilin family.

28377:tbk1
gene id: 28377:tbk1
uniprot id: G1KBS7
names: Subcellular Location Annotation
messages: Cytoplasm

28377:LOC100553449
gene id: 28377:LOC100553449
uniprot id: A0A803T9I6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

28377:pkia
gene id: 28377:pkia
uniprot id: G1KNM1
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

28377:wrb
gene id: 28377:wrb
uniprot id: G1KE30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WRB/GET1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:LOC100561762
gene id: 28377:LOC100561762
uniprot id: G1KT94
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:dcp1a
gene id: 28377:dcp1a
uniprot id: G1KKS9
names: Similarity
messages: Belongs to the DCP1 family.

28377:meis2
gene id: 28377:meis2
uniprot id: A0A803TGH3
uniprot id: A0A803TJP6
uniprot id: G1K8M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

28377:LOC100564712
gene id: 28377:LOC100564712
uniprot id: A0A803U018
names: Similarity
messages: Belongs to the TMEM14 family.

28377:meox2
gene id: 28377:meox2
uniprot id: G1KMW8
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC100564639
gene id: 28377:LOC100564639
uniprot id: G1KFF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

28377:rab3c
gene id: 28377:rab3c
uniprot id: G1KIQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

28377:LOC100558405
gene id: 28377:LOC100558405
uniprot id: G1KNK4
names: Subcellular Location Annotation
messages: Membrane

28377:LOC100557878
gene id: 28377:LOC100557878
uniprot id: R4GBT6
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

28377:ddb2
gene id: 28377:ddb2
uniprot id: A0A803SLK1
uniprot id: G1KBJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Nucleus

28377:tm7sf3
gene id: 28377:tm7sf3
uniprot id: A0A803T749
names: Subcellular Location Annotation
messages: Membrane

28377:LOC100564169
gene id: 28377:LOC100564169
uniprot id: G1KHX4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

28377:cdc14a
gene id: 28377:cdc14a
uniprot id: A0A803TZI5
uniprot id: G1KBN9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

28377:mboat1
gene id: 28377:mboat1
uniprot id: G1KBL2
names: Subcellular Location Annotation
messages: Membrane

28377:ppp1r14a
gene id: 28377:ppp1r14a
uniprot id: H9G8B8
names: Similarity
messages: Belongs to the PP1 inhibitor family.

28377:tmem65
gene id: 28377:tmem65
uniprot id: G1KJI6
names: Subcellular Location Annotation
messages: Membrane

28377:ints7
gene id: 28377:ints7
uniprot id: G1KFM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 7 family.
messages: Nucleus

28377:cs
gene id: 28377:cs
uniprot id: G1KGV0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the citrate synthase family.
messages: Homodimer.
messages: Mitochondrion matrix

28377:flt3
gene id: 28377:flt3
uniprot id: G1KIN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Membrane

28377:mfap5
gene id: 28377:mfap5
uniprot id: G1KTW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

28377:lyplal1
gene id: 28377:lyplal1
uniprot id: A0A803TKH0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

28377:ttc39b
gene id: 28377:ttc39b
uniprot id: G1KUD2
names: Similarity
messages: Belongs to the TTC39 family.

28377:brf1
gene id: 28377:brf1
uniprot id: G1KRH9
names: Similarity
messages: Belongs to the TFIIB family.

28377:sypl1
gene id: 28377:sypl1
uniprot id: G1KQ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

28377:LOC100565029
gene id: 28377:LOC100565029
uniprot id: G1KBV1
names: Similarity
messages: Belongs to the PRORSD1 family.

28377:ndufs6
gene id: 28377:ndufs6
uniprot id: A0A803TY25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS6 subunit family.
messages: Mitochondrion inner membrane

28377:LOC100566498
gene id: 28377:LOC100566498
uniprot id: G1KBT9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28377:pmm1
gene id: 28377:pmm1
uniprot id: G1KD11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

28377:ptpn14
gene id: 28377:ptpn14
uniprot id: G1KF00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

28377:fnip2
gene id: 28377:fnip2
uniprot id: A0A803T985
uniprot id: A0A803TU13
uniprot id: G1KSM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

28377:LOC103279240
gene id: 28377:LOC103279240
uniprot id: G1KVP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

28377:fgfbp2
gene id: 28377:fgfbp2
uniprot id: G1KM24
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

28377:tmem198
gene id: 28377:tmem198
uniprot id: G1KPM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

28377:nkx2-5
gene id: 28377:nkx2-5
uniprot id: G1KQP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NK-2 homeobox family.
messages: Nucleus

28377:apex2
gene id: 28377:apex2
uniprot id: G1KKZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

28377:rab9a
gene id: 28377:rab9a
uniprot id: G1K9R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

28377:stx3
gene id: 28377:stx3
uniprot id: A0A803T112
names: Similarity
messages: Belongs to the syntaxin family.

28377:jagn1
gene id: 28377:jagn1
uniprot id: G1KJC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:c2h2orf88
gene id: 28377:c2h2orf88
uniprot id: A0A803TNT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small membrane AKAP family.
messages: Cell membrane
messages: Membrane

28377:gtf2h4
gene id: 28377:gtf2h4
uniprot id: G1KK03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

28377:akr1d1
gene id: 28377:akr1d1
uniprot id: G1KNT7
names: Similarity
messages: Belongs to the aldo/keto reductase family.

28377:snx5
gene id: 28377:snx5
uniprot id: G1KPK8
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

28377:st3gal1
gene id: 28377:st3gal1
uniprot id: G1KLN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

28377:ywhaq
gene id: 28377:ywhaq
uniprot id: G1K9B0
names: Similarity
messages: Belongs to the 14-3-3 family.

28377:adcyap1
gene id: 28377:adcyap1
uniprot id: A0A803TVX1
uniprot id: G1KI35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

28377:LOC100567693
gene id: 28377:LOC100567693
uniprot id: A0A803TE59
uniprot id: A0A803TQV8
names: Subunit
messages: Monomer.

28377:bmt2
gene id: 28377:bmt2
uniprot id: G1KG09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BMT2 family.
messages: Interacts with the GATOR1 complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine. Interacts with the KICSTOR complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine.
messages: S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.

28377:fam188a
gene id: 28377:fam188a
uniprot id: G1KSW3
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

28377:akap9
gene id: 28377:akap9
uniprot id: A0A803SVH7
names: Subcellular Location Annotation
messages: centrosome

28377:LOC100553851
gene id: 28377:LOC100553851
uniprot id: A0A803T7J2
names: Similarity
messages: Belongs to the intermediate filament family.

28377:LOC100556565
gene id: 28377:LOC100556565
uniprot id: A0A803T3D9
uniprot id: G1KCF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b5 family.
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Endoplasmic reticulum

28377:stat2
gene id: 28377:stat2
uniprot id: G1KV19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

28377:fam76b
gene id: 28377:fam76b
uniprot id: R4G9A0
names: Similarity
messages: Belongs to the FAM76 family.

28377:tpd52l1
gene id: 28377:tpd52l1
uniprot id: A0A803T152
uniprot id: A0A803TRI6
uniprot id: G1K9U2
names: Similarity
messages: Belongs to the TPD52 family.

28377:c4h8orf37
gene id: 28377:c4h8orf37
uniprot id: G1KX11
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in photoreceptor outer segment disk morphogenesis.
messages: Photoreceptor inner segment

28377:adgrl1
gene id: 28377:adgrl1
uniprot id: A0A803SQ51
uniprot id: A0A803T4Y7
uniprot id: G1KL00
names: Subcellular Location Annotation
messages: Membrane

28377:LOC100553835
gene id: 28377:LOC100553835
uniprot id: G1KMK4
names: Similarity
messages: Belongs to the peptidase M10A family.

28377:LOC100564396
gene id: 28377:LOC100564396
uniprot id: G1KYT1
names: Similarity
messages: Belongs to the intermediate filament family.

28377:pdgfb
gene id: 28377:pdgfb
uniprot id: R4GCL3
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

28377:mturn
gene id: 28377:mturn
uniprot id: A0A803TQA5
uniprot id: G1KB92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTURN family.
messages: Cytoplasm

28377:LOC103278754
gene id: 28377:LOC103278754
uniprot id: R4GC76
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:phykpl
gene id: 28377:phykpl
uniprot id: G1KTB5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

28377:slc19a1
gene id: 28377:slc19a1
uniprot id: G1KK60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

28377:ephb1
gene id: 28377:ephb1
uniprot id: G1KIZ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: dendrite

28377:rh2
gene id: 28377:rh2
uniprot id: P51471
uniprot id: Q549F5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. This opsin uses a vitamin A2 chromophore.

28377:prpf18
gene id: 28377:prpf18
uniprot id: G1K8V0
uniprot id: R4GAS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

28377:dicer1
gene id: 28377:dicer1
uniprot id: G1KND9
names: Function
names: Similarity
messages: Belongs to the helicase family. Dicer subfamily.
messages: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes.

28377:mbp
gene id: 28377:mbp
uniprot id: A0A803SS85
uniprot id: A0A803TKL9
uniprot id: A0A803TPR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

28377:glrb
gene id: 28377:glrb
uniprot id: G1KT50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

28377:glis3
gene id: 28377:glis3
uniprot id: A0A803T5Z4
uniprot id: G1KBV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

28377:smc1a
gene id: 28377:smc1a
uniprot id: G1KJ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

28377:odf2l
gene id: 28377:odf2l
uniprot id: A0A803TLG9
uniprot id: G1KPI8
uniprot id: G1KYP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

28377:psen2
gene id: 28377:psen2
uniprot id: G1KFF8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

28377:gpr65
gene id: 28377:gpr65
uniprot id: G1KNM2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:zdhhc20
gene id: 28377:zdhhc20
uniprot id: A0A803TNM9
uniprot id: G1KB70
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

28377:cdk19
gene id: 28377:cdk19
uniprot id: G1KKT2
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:LOC100560370
gene id: 28377:LOC100560370
uniprot id: G1KSR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

28377:mrpl12
gene id: 28377:mrpl12
uniprot id: G1KKH4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

28377:dync1i1
gene id: 28377:dync1i1
uniprot id: A0A803SN77
uniprot id: G1KQ03
names: Similarity
messages: Belongs to the dynein intermediate chain family.

28377:gmppb
gene id: 28377:gmppb
uniprot id: G1KGR0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

28377:spry1
gene id: 28377:spry1
uniprot id: G1KLF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sprouty family.
messages: Cytoplasm
messages: Membrane

28377:msra
gene id: 28377:msra
uniprot id: G1KJN4
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

28377:nrp1
gene id: 28377:nrp1
uniprot id: G1KFQ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:lmod3
gene id: 28377:lmod3
uniprot id: G1KR11
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

28377:fam216b
gene id: 28377:fam216b
uniprot id: A0A803TS19
names: Similarity
messages: Belongs to the FAM216 family.

28377:tmem251
gene id: 28377:tmem251
uniprot id: G1KI71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM251 family.
messages: Membrane

28377:prpsap1
gene id: 28377:prpsap1
uniprot id: G1KHJ6
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

28377:appl2
gene id: 28377:appl2
uniprot id: G1KRF1
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Nucleus
messages: phagosome
messages: ruffle

28377:opn5
gene id: 28377:opn5
uniprot id: G1KNV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

28377:snx30
gene id: 28377:snx30
uniprot id: G1KTU9
names: Similarity
messages: Belongs to the sorting nexin family.

28377:stk3
gene id: 28377:stk3
uniprot id: G1KSA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

28377:LOC100556198
gene id: 28377:LOC100556198
uniprot id: G1KT72
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

28377:atp6v0d2
gene id: 28377:atp6v0d2
uniprot id: G1KJ03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

28377:pmp22
gene id: 28377:pmp22
uniprot id: A0A803T054
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Might be involved in growth regulation, and in myelinization in the peripheral nervous system.

28377:siah1
gene id: 28377:siah1
uniprot id: H9GL05
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

28377:gcgr
gene id: 28377:gcgr
uniprot id: G1KKF1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28377:oat
gene id: 28377:oat
uniprot id: G1KU46
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

28377:hnrnpd
gene id: 28377:hnrnpd
uniprot id: A0A803T0C8
uniprot id: G1KK21
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

28377:LOC100558465
gene id: 28377:LOC100558465
uniprot id: L7MZI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

28377:wasl
gene id: 28377:wasl
uniprot id: G1K952
uniprot id: R4GBY4
names: Subcellular Location Annotation
messages: Nucleus

28377:pold1
gene id: 28377:pold1
uniprot id: G1KXJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

28377:kcns3
gene id: 28377:kcns3
uniprot id: G1K9L4
names: Subcellular Location Annotation
messages: Membrane

28377:ampd1
gene id: 28377:ampd1
uniprot id: A0A803SSR9
uniprot id: G1KBG7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

28377:tecr
gene id: 28377:tecr
uniprot id: G1KTG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:scoc
gene id: 28377:scoc
uniprot id: A0A803TNR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCOC family.
messages: Positive regulator of amino acid starvation-induced autophagy.
messages: trans-Golgi network

28377:nkain3
gene id: 28377:nkain3
uniprot id: A0A803SZ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

28377:gabra5
gene id: 28377:gabra5
uniprot id: G1KL95
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

28377:zhx1
gene id: 28377:zhx1
uniprot id: G1KJ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

28377:hddc2
gene id: 28377:hddc2
uniprot id: G1K9V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

28377:crybg3
gene id: 28377:crybg3
uniprot id: A0A803T6B7
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

28377:nprl2
gene id: 28377:nprl2
uniprot id: G1KFZ4
names: Similarity
messages: Belongs to the NPR2 family.

28377:ucma
gene id: 28377:ucma
uniprot id: G1K954
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UCMA family.
messages: May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.
messages: extracellular matrix

28377:tbl1x
gene id: 28377:tbl1x
uniprot id: A0A803TNJ4
uniprot id: A0A803TQK0
names: Similarity
messages: Belongs to the WD repeat EBI family.

28377:cldn18
gene id: 28377:cldn18
uniprot id: G1KIJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

28377:mtnr1b
gene id: 28377:mtnr1b
uniprot id: A0A803T9J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:nup205
gene id: 28377:nup205
uniprot id: G1KL92
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

28377:pln
gene id: 28377:pln
uniprot id: G1KUA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholamban family.
messages: Endoplasmic reticulum membrane
messages: Homopentamer.
messages: Membrane
messages: Mitochondrion membrane
messages: Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
messages: Sarcoplasmic reticulum membrane

28377:tyms
gene id: 28377:tyms
uniprot id: G1KHU7
names: Similarity
messages: Belongs to the thymidylate synthase family.

28377:atp2b3
gene id: 28377:atp2b3
uniprot id: A0A803U024
uniprot id: G1KJ35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:fam212a
gene id: 28377:fam212a
uniprot id: A0A803TZ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

28377:fmo5
gene id: 28377:fmo5
uniprot id: G1KYK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as Baeyer-Villiger monooxygenase on a broad range of substrates. Catalyzes the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters.
messages: Belongs to the FMO family.
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

28377:gnb4
gene id: 28377:gnb4
uniprot id: G1KD23
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

28377:arfgef2
gene id: 28377:arfgef2
uniprot id: A0A803SLE5
uniprot id: G1KS74
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

28377:dgkb
gene id: 28377:dgkb
uniprot id: G1KN57
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

28377:lrrc8d
gene id: 28377:lrrc8d
uniprot id: G1KUQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

28377:esco1
gene id: 28377:esco1
uniprot id: G1KH60
names: Subcellular Location Annotation
messages: Nucleus

28377:rmi1
gene id: 28377:rmi1
uniprot id: G1K9F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RMI1 family.
messages: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
messages: Nucleus

28377:ND4
gene id: 28377:ND4
uniprot id: B3GSZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion membrane

28377:tead3
gene id: 28377:tead3
uniprot id: G1KIN3
uniprot id: R4GA16
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

28377:osbpl1a
gene id: 28377:osbpl1a
uniprot id: A0A803T9U9
uniprot id: G1K9P2
names: Similarity
messages: Belongs to the OSBP family.

28377:cdk3
gene id: 28377:cdk3
uniprot id: G1KH44
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:sft2d2
gene id: 28377:sft2d2
uniprot id: G1KKG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

28377:ptges3
gene id: 28377:ptges3
uniprot id: G1KIJ3
names: Similarity
messages: Belongs to the p23/wos2 family.

28377:LOC100557280
gene id: 28377:LOC100557280
uniprot id: R4G9T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

28377:tfpi2
gene id: 28377:tfpi2
uniprot id: G1KNH2
names: Subcellular Location Annotation
messages: Secreted

28377:serpine2
gene id: 28377:serpine2
uniprot id: G1KCT2
names: Similarity
messages: Belongs to the serpin family.

28377:bco1
gene id: 28377:bco1
uniprot id: H9GES3
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

28377:LOC103278034
gene id: 28377:LOC103278034
uniprot id: G1KLF5
names: Subcellular Location Annotation
messages: Secreted

28377:adam8
gene id: 28377:adam8
uniprot id: G1KTY5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:LOC100552978
gene id: 28377:LOC100552978
uniprot id: G1KUR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

28377:mrpl44
gene id: 28377:mrpl44
uniprot id: G1KCK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.
messages: Mitochondrion

28377:lxn
gene id: 28377:lxn
uniprot id: G1KFW7
names: Similarity
messages: Belongs to the protease inhibitor I47 (latexin) family.

28377:entpd7
gene id: 28377:entpd7
uniprot id: G1KC74
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

28377:LOC100557857
gene id: 28377:LOC100557857
uniprot id: A0A803SQ92
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

28377:ahcyl1
gene id: 28377:ahcyl1
uniprot id: G1KM02
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

28377:spopl
gene id: 28377:spopl
uniprot id: G1K8H7
names: Similarity
messages: Belongs to the Tdpoz family.

28377:LOC100564767
gene id: 28377:LOC100564767
uniprot id: G1KHE2
names: Subcellular Location Annotation
messages: Nucleus

28377:slc25a3
gene id: 28377:slc25a3
uniprot id: G1KNG5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Interacts with PPIF; the interaction is impaired by CsA.
messages: Membrane
messages: Mitochondrion inner membrane

28377:idh1
gene id: 28377:idh1
uniprot id: G1KJG1
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

28377:atp5g2
gene id: 28377:atp5g2
uniprot id: G1K987
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

28377:dusp3
gene id: 28377:dusp3
uniprot id: G1KD57
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

28377:ND3
gene id: 28377:ND3
uniprot id: B3GSZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

28377:LOC100566351
gene id: 28377:LOC100566351
uniprot id: G1KRR3
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:elavl2
gene id: 28377:elavl2
uniprot id: A0A803SPV3
uniprot id: G1KU25
names: Similarity
messages: Belongs to the RRM elav family.

28377:crmp1
gene id: 28377:crmp1
uniprot id: G1KQV0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

28377:snx11
gene id: 28377:snx11
uniprot id: G1KFI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

28377:lpcat1
gene id: 28377:lpcat1
uniprot id: G1K8X6
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

28377:sulf2
gene id: 28377:sulf2
uniprot id: A0A803T8H3
uniprot id: G1KSG0
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

28377:nr0b1
gene id: 28377:nr0b1
uniprot id: A0A803T644
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

28377:grb10
gene id: 28377:grb10
uniprot id: G1KHW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

28377:hnrnpk
gene id: 28377:hnrnpk
uniprot id: G1K9R8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleoplasm

28377:c1h11orf49
gene id: 28377:c1h11orf49
uniprot id: G1KBR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSTPP1 family.
messages: centriolar satellite

28377:ppil3
gene id: 28377:ppil3
uniprot id: G1KTF5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

28377:slc16a7
gene id: 28377:slc16a7
uniprot id: G1K9H3
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cytoplasm
messages: Membrane

28377:grm6
gene id: 28377:grm6
uniprot id: G1KFJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

28377:cldn14
gene id: 28377:cldn14
uniprot id: G1KMQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

28377:c3h11orf70
gene id: 28377:c3h11orf70
uniprot id: G1KMT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP300 family.
messages: Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly.
messages: Cytoplasm

28377:atp6v0e1
gene id: 28377:atp6v0e1
uniprot id: G1KQR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

28377:slc4a1
gene id: 28377:slc4a1
uniprot id: G1KTP9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:nup85
gene id: 28377:nup85
uniprot id: G1KF71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: nuclear pore complex

28377:ndrg3
gene id: 28377:ndrg3
uniprot id: A0A803TVD0
uniprot id: G1KFN4
names: Similarity
messages: Belongs to the NDRG family.

28377:trpc3
gene id: 28377:trpc3
uniprot id: A0A803TJ37
uniprot id: G1KME8
names: Subcellular Location Annotation
messages: Membrane

28377:ric8b
gene id: 28377:ric8b
uniprot id: G1KQY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

28377:LOC100557873
gene id: 28377:LOC100557873
uniprot id: G1KQX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

28377:kcna10
gene id: 28377:kcna10
uniprot id: G1KRX8
names: Subcellular Location Annotation
messages: Membrane

28377:LOC100565436
gene id: 28377:LOC100565436
uniprot id: G1KAM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

28377:grm1
gene id: 28377:grm1
uniprot id: A0A803T4R7
uniprot id: G1KGH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

28377:hsdl2
gene id: 28377:hsdl2
uniprot id: G1KTT6
names: Subcellular Location Annotation
messages: Peroxisome

28377:cd47
gene id: 28377:cd47
uniprot id: R4GAV1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28377:LOC100559308
gene id: 28377:LOC100559308
uniprot id: G1KI64
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

28377:rbm12
gene id: 28377:rbm12
uniprot id: G1KF90
names: Similarity
messages: Belongs to the copine family.

28377:fam126a
gene id: 28377:fam126a
uniprot id: A0A803TCX7
uniprot id: G1KPE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM126 family.
messages: Cell membrane
messages: Membrane
messages: cytosol

28377:svopl
gene id: 28377:svopl
uniprot id: G1KP06
names: Subcellular Location Annotation
messages: Membrane

28377:mmp16
gene id: 28377:mmp16
uniprot id: A0A803TPW0
names: Similarity
messages: Belongs to the peptidase M10A family.

28377:myo1b
gene id: 28377:myo1b
uniprot id: A0A803SKX1
uniprot id: A0A803T3K2
uniprot id: A0A803TJG8
uniprot id: A0A803TSF2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

28377:pomgnt2
gene id: 28377:pomgnt2
uniprot id: G1KBI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 61 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:fzd4
gene id: 28377:fzd4
uniprot id: G1KB27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

28377:mical3
gene id: 28377:mical3
uniprot id: G1KMJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
messages: Nucleus
messages: cytoskeleton

28377:tmem18
gene id: 28377:tmem18
uniprot id: R4GCR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM18 family.
messages: Membrane
messages: Nucleus membrane

28377:emc3
gene id: 28377:emc3
uniprot id: A0A803THP1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

28377:cnot9
gene id: 28377:cnot9
uniprot id: G1KAW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT9 family.
messages: P-body

28377:wdfy1
gene id: 28377:wdfy1
uniprot id: G1KCW8
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

28377:tpmt
gene id: 28377:tpmt
uniprot id: G1KBT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

28377:cnot6
gene id: 28377:cnot6
uniprot id: G1KSS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

28377:dpyd
gene id: 28377:dpyd
uniprot id: A0A803TH67
uniprot id: G1KED2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
messages: Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.
messages: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine.

28377:LOC100553914
gene id: 28377:LOC100553914
uniprot id: G1KS40
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

28377:ptdss1
gene id: 28377:ptdss1
uniprot id: G1KCP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:LOC100567189
gene id: 28377:LOC100567189
uniprot id: R4GD21
names: Similarity
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.

28377:tmem168
gene id: 28377:tmem168
uniprot id: G1KG11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM168 family.
messages: Membrane

28377:ifrd2
gene id: 28377:ifrd2
uniprot id: G1KI72
names: Similarity
messages: Belongs to the IFRD family.

28377:mecom
gene id: 28377:mecom
uniprot id: G1KRE9
names: Subcellular Location Annotation
messages: Nucleus

28377:bysl
gene id: 28377:bysl
uniprot id: G1KBH5
names: Similarity
messages: Belongs to the bystin family.

28377:LOC100562074
gene id: 28377:LOC100562074
uniprot id: A0A803TKC8
uniprot id: G1KN24
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

28377:LOC100552047
gene id: 28377:LOC100552047
uniprot id: G1KGT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:b3galnt2
gene id: 28377:b3galnt2
uniprot id: G1K9Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

28377:dnmbp
gene id: 28377:dnmbp
uniprot id: G1KCK3
names: Subcellular Location Annotation
messages: Cell junction
messages: Golgi stack
messages: Synapse
messages: cytoskeleton

28377:ncoa3
gene id: 28377:ncoa3
uniprot id: G1KSL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

28377:dhrs7c
gene id: 28377:dhrs7c
uniprot id: G1KTB0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28377:tmem2
gene id: 28377:tmem2
uniprot id: G1KN10
names: Similarity
messages: Belongs to the CEMIP family.

28377:itgb7
gene id: 28377:itgb7
uniprot id: G1KFZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

28377:ttc27
gene id: 28377:ttc27
uniprot id: A0A803SQ39
uniprot id: G1KIC6
names: Similarity
messages: Belongs to the TTC27 family.

28377:dnase1l3
gene id: 28377:dnase1l3
uniprot id: G1KA37
names: Similarity
messages: Belongs to the DNase I family.

28377:LOC103278887
gene id: 28377:LOC103278887
uniprot id: A0A803T3C6
names: Similarity
messages: Belongs to the CRISP family.

28377:cenpm
gene id: 28377:cenpm
uniprot id: A0A803TL21
names: Subcellular Location Annotation
messages: Nucleus

28377:acox2
gene id: 28377:acox2
uniprot id: G1KLB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

28377:cdca7l
gene id: 28377:cdca7l
uniprot id: G1KPI5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

28377:sec22a
gene id: 28377:sec22a
uniprot id: G1KKS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

28377:lhx4
gene id: 28377:lhx4
uniprot id: A0A803TUW7
uniprot id: G1K8W9
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC100554941
gene id: 28377:LOC100554941
uniprot id: G1KEP9
uniprot id: G1KZ17
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

28377:xpot
gene id: 28377:xpot
uniprot id: G1KBN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

28377:LOC100563066
gene id: 28377:LOC100563066
uniprot id: G1KD62
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

28377:tns1
gene id: 28377:tns1
uniprot id: A0A803TBX2
uniprot id: G1K8Y8
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

28377:oaf
gene id: 28377:oaf
uniprot id: H9G7J5
names: Similarity
messages: Belongs to the OAF family.

28377:ccr6
gene id: 28377:ccr6
uniprot id: G1KK39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

28377:syngr1
gene id: 28377:syngr1
uniprot id: A0A803TSR4
uniprot id: G1KXB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

28377:manea
gene id: 28377:manea
uniprot id: G1KAJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

28377:lamp3
gene id: 28377:lamp3
uniprot id: G1KGN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

28377:rragd
gene id: 28377:rragd
uniprot id: G1KPY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

28377:jag2
gene id: 28377:jag2
uniprot id: A0A803THM0
uniprot id: G1KJ33
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

28377:znf622
gene id: 28377:znf622
uniprot id: G1K8F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

28377:pigu
gene id: 28377:pigu
uniprot id: G1KIW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:fzd1
gene id: 28377:fzd1
uniprot id: G1KRK4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:slc35c1
gene id: 28377:slc35c1
uniprot id: G1KQ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPT transporter family. SLC35C subfamily.
messages: Membrane

28377:ipo13
gene id: 28377:ipo13
uniprot id: G1KPQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the importin beta family.
messages: Cytoplasm
messages: Interacts with UBC9, RAN, RBM8A, eIF-1A and PAX6.
messages: Nucleus

28377:timeless
gene id: 28377:timeless
uniprot id: G1KSP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the timeless family.
messages: Nucleus

28377:slc35a5
gene id: 28377:slc35a5
uniprot id: A0A803TYY4
uniprot id: G1KJW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

28377:tnfsf14
gene id: 28377:tnfsf14
uniprot id: A0A803SYA8
names: Similarity
messages: Belongs to the tumor necrosis factor family.

28377:atp5o
gene id: 28377:atp5o
uniprot id: G1KDI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

28377:med25
gene id: 28377:med25
uniprot id: A0A803SYN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 25 family.
messages: Nucleus

28377:htr1e
gene id: 28377:htr1e
uniprot id: G1KQU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:vps41
gene id: 28377:vps41
uniprot id: A0A803TP13
uniprot id: G1KU87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network

28377:tmem123
gene id: 28377:tmem123
uniprot id: G1KMK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

28377:aqp1
gene id: 28377:aqp1
uniprot id: G1KEQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

28377:cep76
gene id: 28377:cep76
uniprot id: G1KNT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP76 family.
messages: Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication.
messages: centriole

28377:sec22b
gene id: 28377:sec22b
uniprot id: A0A803TX37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

28377:ptgr2
gene id: 28377:ptgr2
uniprot id: G1KRZ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer.

28377:zufsp
gene id: 28377:zufsp
uniprot id: A0A803TYT4
names: Similarity
names: Subunit
messages: Belongs to the peptidase C78 family. ZUFSP subfamily.
messages: Interacts with RPA1 and RPA2.

28377:LOC103277700
gene id: 28377:LOC103277700
uniprot id: R4G941
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

28377:khsrp
gene id: 28377:khsrp
uniprot id: G1KR51
names: Subcellular Location Annotation
messages: Nucleus

28377:fgfr1op
gene id: 28377:fgfr1op
uniprot id: G1KK59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP43 family.
messages: cilium basal body

28377:itprip
gene id: 28377:itprip
uniprot id: G1KDR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Cell membrane
messages: Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release.
messages: Membrane
messages: Nucleus outer membrane

28377:c5h6orf120
gene id: 28377:c5h6orf120
uniprot id: G1KEF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0669 family.
messages: Secreted

28377:LOC100565746
gene id: 28377:LOC100565746
uniprot id: G1KD81
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:LOC100558726
gene id: 28377:LOC100558726
uniprot id: G1KZC5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

28377:ifrd1
gene id: 28377:ifrd1
uniprot id: A0A803TZK1
uniprot id: G1KG48
names: Similarity
messages: Belongs to the IFRD family.

28377:hmmr
gene id: 28377:hmmr
uniprot id: R4G9R9
names: Subcellular Location Annotation
messages: Nucleus
messages: spindle

28377:baz2a
gene id: 28377:baz2a
uniprot id: G1KT13
names: Similarity
messages: Belongs to the WAL family.

28377:mmachc
gene id: 28377:mmachc
uniprot id: G1KQS9
names: Similarity
messages: Belongs to the MMACHC family.

28377:slc16a4
gene id: 28377:slc16a4
uniprot id: A0A803SZH6
uniprot id: G1KMT8
names: Subcellular Location Annotation
messages: Membrane

28377:mfsd8
gene id: 28377:mfsd8
uniprot id: G1KL78
names: Subcellular Location Annotation
messages: Membrane

28377:hpdl
gene id: 28377:hpdl
uniprot id: A0A803STW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

28377:LOC100562953
gene id: 28377:LOC100562953
uniprot id: L7MZN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

28377:pcyox1l
gene id: 28377:pcyox1l
uniprot id: G1KRC4
names: Similarity
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
messages: Belongs to the prenylcysteine oxidase family.

28377:rps21
gene id: 28377:rps21
uniprot id: A0A803T1Q3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

28377:mcph1
gene id: 28377:mcph1
uniprot id: G1KVY5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex.
messages: Interacts with CDC27 and maybe other components of the APC/C complex. Interacts with histone variant H2AX under DNA damage conditions.
messages: centrosome

28377:gpr20
gene id: 28377:gpr20
uniprot id: G1K8N8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:grpr
gene id: 28377:grpr
uniprot id: G1KTG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:LOC100554550
gene id: 28377:LOC100554550
uniprot id: G1KN84
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

28377:hyi
gene id: 28377:hyi
uniprot id: G1KNW7
names: Function
names: Similarity
messages: Belongs to the hyi family.
messages: Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).

28377:nol12
gene id: 28377:nol12
uniprot id: G1KR91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

28377:tssc1
gene id: 28377:tssc1
uniprot id: G1KEQ7
names: Similarity
messages: Belongs to the WD repeat EIPR1 family.

28377:trappc11
gene id: 28377:trappc11
uniprot id: G1KBN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPPC11 family.
messages: Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
messages: cis-Golgi network

28377:sec63
gene id: 28377:sec63
uniprot id: G1KET9
names: Subcellular Location Annotation
messages: Membrane

28377:rgn
gene id: 28377:rgn
uniprot id: G1KLQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

28377:eaf2
gene id: 28377:eaf2
uniprot id: G1KD80
names: Similarity
messages: Belongs to the EAF family.

28377:nr4a3
gene id: 28377:nr4a3
uniprot id: G1KIE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

28377:erap1
gene id: 28377:erap1
uniprot id: G1KMG9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

28377:ltc4s
gene id: 28377:ltc4s
uniprot id: R4GBF4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

28377:esr2
gene id: 28377:esr2
uniprot id: G1KRR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

28377:htr1f
gene id: 28377:htr1f
uniprot id: G1KP41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
messages: Membrane

28377:hus1
gene id: 28377:hus1
uniprot id: G1KHF0
names: Similarity
messages: Belongs to the HUS1 family.

28377:cdk20
gene id: 28377:cdk20
uniprot id: G1KH48
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:LOC100553319
gene id: 28377:LOC100553319
uniprot id: G1KWP1
names: Subcellular Location Annotation
messages: Secreted

28377:eif3e
gene id: 28377:eif3e
uniprot id: G1KJX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm
messages: Nucleus

28377:LOC103278362
gene id: 28377:LOC103278362
uniprot id: G1KE10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

28377:grm3
gene id: 28377:grm3
uniprot id: G1KSM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

28377:slc12a4
gene id: 28377:slc12a4
uniprot id: H9GFF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

28377:gpr89b
gene id: 28377:gpr89b
uniprot id: G1KPD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Golgi pH regulator (TC 1.A.38) family.
messages: Membrane

28377:synj1
gene id: 28377:synj1
uniprot id: A0A803SUB3
uniprot id: A0A803TUK8
uniprot id: G1KY92
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

28377:LOC100565553
gene id: 28377:LOC100565553
uniprot id: A0A803SNV0
names: Similarity
messages: Belongs to the TCP10 family.

28377:fgf19
gene id: 28377:fgf19
uniprot id: G1KS16
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

28377:ND6
gene id: 28377:ND6
uniprot id: B3GT01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion membrane

28377:tmem9b
gene id: 28377:tmem9b
uniprot id: G1KJE7
names: Similarity
messages: Belongs to the TMEM9 family.

28377:crispld1
gene id: 28377:crispld1
uniprot id: G1KNF4
names: Similarity
messages: Belongs to the CRISP family.

28377:slc35a4
gene id: 28377:slc35a4
uniprot id: G1KN33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

28377:nsmce4a
gene id: 28377:nsmce4a
uniprot id: G1KTQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus
messages: telomere

28377:taldo1
gene id: 28377:taldo1
uniprot id: G1KQV8
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

28377:atp5h
gene id: 28377:atp5h
uniprot id: G1KEZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

28377:rab3d
gene id: 28377:rab3d
uniprot id: G1KT46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

28377:nceh1
gene id: 28377:nceh1
uniprot id: G1KSJ9
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

28377:prkd1
gene id: 28377:prkd1
uniprot id: A0A803SR45
uniprot id: A0A803TTW3
uniprot id: G1KS05
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

28377:sh3bp5
gene id: 28377:sh3bp5
uniprot id: G1KB58
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

28377:slc16a14
gene id: 28377:slc16a14
uniprot id: G1KE06
names: Subcellular Location Annotation
messages: Membrane

28377:vps37a
gene id: 28377:vps37a
uniprot id: G1KF83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

28377:cxxc5
gene id: 28377:cxxc5
uniprot id: A0A803TTG3
uniprot id: G1KAB6
names: Subcellular Location Annotation
messages: Cytoplasm

28377:tgif1
gene id: 28377:tgif1
uniprot id: A0A803TS58
names: Subcellular Location Annotation
messages: Nucleus

28377:nhp2
gene id: 28377:nhp2
uniprot id: G1KFL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

28377:gpr37
gene id: 28377:gpr37
uniprot id: G1K991
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28377:srp9
gene id: 28377:srp9
uniprot id: G1KEM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

28377:LOC100567335
gene id: 28377:LOC100567335
uniprot id: G1KUL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

28377:mettl1
gene id: 28377:mettl1
uniprot id: G1KN86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with WDR4.
messages: Nucleus

28377:gns
gene id: 28377:gns
uniprot id: G1KBV9
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

28377:uhrf2
gene id: 28377:uhrf2
uniprot id: G1KCR6
names: Subcellular Location Annotation
messages: Nucleus

28377:prdx6
gene id: 28377:prdx6
uniprot id: A0A803TBB8
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

28377:cd164
gene id: 28377:cd164
uniprot id: A0A803TD01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

28377:enpp1
gene id: 28377:enpp1
uniprot id: G1K9C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Secreted

28377:megf10
gene id: 28377:megf10
uniprot id: A0A803SQJ0
uniprot id: G1KB28
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:tp53i11
gene id: 28377:tp53i11
uniprot id: G1KPZ1
names: Subcellular Location Annotation
messages: Membrane

28377:sars
gene id: 28377:sars
uniprot id: G1KK14
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

28377:mrps31
gene id: 28377:mrps31
uniprot id: G1KSV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS31 family.
messages: Mitochondrion

28377:LOC100553182
gene id: 28377:LOC100553182
uniprot id: G1KNZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

28377:tdp2
gene id: 28377:tdp2
uniprot id: G1KAK0
names: Subcellular Location Annotation
messages: PML body

28377:stk4
gene id: 28377:stk4
uniprot id: G1KLZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

28377:kif25
gene id: 28377:kif25
uniprot id: A0A803T3Q0
uniprot id: G1KYN1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

28377:ptcd3
gene id: 28377:ptcd3
uniprot id: G1KLU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS39 family.
messages: Mitochondrion

28377:mogat1
gene id: 28377:mogat1
uniprot id: G1KD42
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:prdm4
gene id: 28377:prdm4
uniprot id: A0A803SVX3
uniprot id: A0A803T0L2
uniprot id: A0A803TTV5
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor involved in cell differentiation.
messages: Nucleus

28377:fam3a
gene id: 28377:fam3a
uniprot id: G1KDG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

28377:cnot7
gene id: 28377:cnot7
uniprot id: G1KF69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

28377:egfr
gene id: 28377:egfr
uniprot id: G1KTY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

28377:cdc42ep3
gene id: 28377:cdc42ep3
uniprot id: G1KHW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

28377:LOC100556956
gene id: 28377:LOC100556956
uniprot id: G1KKD3
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

28377:unc50
gene id: 28377:unc50
uniprot id: G1KMM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

28377:cpt1c
gene id: 28377:cpt1c
uniprot id: G1KP61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

28377:mlnr
gene id: 28377:mlnr
uniprot id: G1K9N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:gata6
gene id: 28377:gata6
uniprot id: G1KH24
names: Subcellular Location Annotation
messages: Nucleus

28377:fam109b
gene id: 28377:fam109b
uniprot id: G1KCC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

28377:rrp36
gene id: 28377:rrp36
uniprot id: A0A803SZ90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
messages: nucleolus

28377:yipf3
gene id: 28377:yipf3
uniprot id: G1KJA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis.
messages: Membrane
messages: cis-Golgi network membrane

28377:nudt6
gene id: 28377:nudt6
uniprot id: G1KLL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Cytoplasm
messages: May contribute to the regulation of cell proliferation.
messages: Mitochondrion
messages: Monomer and homodimer.
messages: Nucleus

28377:kcne2
gene id: 28377:kcne2
uniprot id: A0A803SXX4
names: Similarity
messages: Belongs to the potassium channel KCNE family.

28377:tmem205
gene id: 28377:tmem205
uniprot id: A0A803TKP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM205 family.
messages: Membrane

28377:pld1
gene id: 28377:pld1
uniprot id: G1KSE7
names: Similarity
messages: Belongs to the phospholipase D family.

28377:magoh
gene id: 28377:magoh
uniprot id: G1KI51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

28377:rgs4
gene id: 28377:rgs4
uniprot id: G1KG87
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.

28377:fnbp1l
gene id: 28377:fnbp1l
uniprot id: A0A803TNT3
uniprot id: G1KE72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNBP1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Membrane
messages: Vesicle
messages: cell cortex
messages: cytoskeleton

28377:acyp2
gene id: 28377:acyp2
uniprot id: A0A803SL11
names: Similarity
messages: Belongs to the acylphosphatase family.

28377:sept2
gene id: 28377:sept2
uniprot id: G1K9J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

28377:fos
gene id: 28377:fos
uniprot id: G1KTB4
names: Similarity
messages: Belongs to the bZIP family. Fos subfamily.

28377:scn8a
gene id: 28377:scn8a
uniprot id: A0A803TCI4
uniprot id: F9W2Y6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

28377:kmt5b
gene id: 28377:kmt5b
uniprot id: A0A803TAG6
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

28377:LOC100556446
gene id: 28377:LOC100556446
uniprot id: G1KYJ0
names: Similarity
messages: Belongs to the PROTOR family.

28377:dhx29
gene id: 28377:dhx29
uniprot id: G1KR16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity.
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Cytoplasm
messages: Part of the 43S pre-initiation complex (PIC).

28377:bcdin3d
gene id: 28377:bcdin3d
uniprot id: G1KHR3
names: Similarity
messages: Belongs to the methyltransferase superfamily.

28377:galr3
gene id: 28377:galr3
uniprot id: A0A803T956
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

28377:ndrg1
gene id: 28377:ndrg1
uniprot id: G1KLK6
names: Similarity
messages: Belongs to the NDRG family.

28377:anxa5
gene id: 28377:anxa5
uniprot id: G1KMZ9
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

28377:LOC100552049
gene id: 28377:LOC100552049
uniprot id: A0A803T2A8
uniprot id: A0A803T772
uniprot id: A0A803TLL0
uniprot id: G1KUP7
uniprot id: G1KUU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

28377:tmx2
gene id: 28377:tmx2
uniprot id: G1KG21
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

28377:lpgat1
gene id: 28377:lpgat1
uniprot id: A0A803TFS3
uniprot id: G1KSF2
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

28377:cxcr4
gene id: 28377:cxcr4
uniprot id: G1K8R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: Lysosome
messages: Membrane

28377:s1pr1
gene id: 28377:s1pr1
uniprot id: A0A803T1B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:gsc
gene id: 28377:gsc
uniprot id: G1KN40
names: Subcellular Location Annotation
messages: Nucleus

28377:ppfia4
gene id: 28377:ppfia4
uniprot id: A0A803SZR4
uniprot id: G1KDB2
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

28377:gabrg2
gene id: 28377:gabrg2
uniprot id: A0A803SWE3
uniprot id: G1KQE5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

28377:tmed9
gene id: 28377:tmed9
uniprot id: G1KFI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:slc25a6
gene id: 28377:slc25a6
uniprot id: A0A803TIW0
uniprot id: G1KEX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

28377:LOC100337549
gene id: 28377:LOC100337549
uniprot id: B6Z1W2
names: Similarity
messages: Belongs to the intermediate filament family.

28377:snap25
gene id: 28377:snap25
uniprot id: G1KA11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
messages: synaptosome

28377:lsm6
gene id: 28377:lsm6
uniprot id: G1KCF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

28377:adssl1
gene id: 28377:adssl1
uniprot id: G1KLI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

28377:xrcc3
gene id: 28377:xrcc3
uniprot id: G1KKH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Cytoplasm
messages: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions.
messages: Nucleus

28377:inpp4b
gene id: 28377:inpp4b
uniprot id: A0A803T0L6
uniprot id: G1KB71
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

28377:mmp2
gene id: 28377:mmp2
uniprot id: H9GNC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: extracellular matrix

28377:emc2
gene id: 28377:emc2
uniprot id: A0A803SRQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

28377:grik1
gene id: 28377:grik1
uniprot id: A0A803SWH0
uniprot id: A0A803T2M3
uniprot id: G1KAD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

28377:taf1d
gene id: 28377:taf1d
uniprot id: G1KQ11
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. Interacts with UBTF.
messages: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
messages: Nucleus

28377:slc46a3
gene id: 28377:slc46a3
uniprot id: G1KJ59
names: Subcellular Location Annotation
messages: Membrane

28377:LOC100565895
gene id: 28377:LOC100565895
uniprot id: R4G9F0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

28377:arl6
gene id: 28377:arl6
uniprot id: A0A803SR74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

28377:tdrd9
gene id: 28377:tdrd9
uniprot id: G1KKN5
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily.

28377:znf830
gene id: 28377:znf830
uniprot id: G1KJC6
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

28377:psmb3
gene id: 28377:psmb3
uniprot id: G1KNE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

28377:slc35b4
gene id: 28377:slc35b4
uniprot id: A0A803TED3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

28377:efemp1
gene id: 28377:efemp1
uniprot id: A0A803U1U1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:ATP8
gene id: 28377:ATP8
uniprot id: B3GSZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase protein 8 family.
messages: Membrane
messages: Mitochondrion membrane

28377:f2
gene id: 28377:f2
uniprot id: G1KCA5
names: Caution
names: Function
names: Similarity
messages: Belongs to the peptidase S1 family. Snake venom subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

28377:alg2
gene id: 28377:alg2
uniprot id: G1KIF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
messages: Membrane

28377:dpys
gene id: 28377:dpys
uniprot id: G1KJD0
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

28377:mov10
gene id: 28377:mov10
uniprot id: G1KUK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

28377:gosr2
gene id: 28377:gosr2
uniprot id: A0A803TWJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOSR2 family.
messages: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
messages: Membrane

28377:tmem242
gene id: 28377:tmem242
uniprot id: R4GC78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

28377:lclat1
gene id: 28377:lclat1
uniprot id: A0A803TUY3
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

28377:hdhd2
gene id: 28377:hdhd2
uniprot id: A0A803SKK1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

28377:LOC100556702
gene id: 28377:LOC100556702
uniprot id: G1KEU6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:aldh5a1
gene id: 28377:aldh5a1
uniprot id: G1KB06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
messages: Homotetramer.
messages: Mitochondrion

28377:gli2
gene id: 28377:gli2
uniprot id: G1KCN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

28377:tspan10
gene id: 28377:tspan10
uniprot id: G1KQN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

28377:mrpl16
gene id: 28377:mrpl16
uniprot id: G1KJH6
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

28377:snx6
gene id: 28377:snx6
uniprot id: A0A803T4I4
uniprot id: G1KAW0
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

28377:tshb
gene id: 28377:tshb
uniprot id: A0A803ST38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

28377:LOC100557286
gene id: 28377:LOC100557286
uniprot id: G1KYZ2
uniprot id: R4GAB8
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

28377:cxcr1
gene id: 28377:cxcr1
uniprot id: G1K910
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:rala
gene id: 28377:rala
uniprot id: G1KU67
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

28377:nell2
gene id: 28377:nell2
uniprot id: G1KB72
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:cacna2d3
gene id: 28377:cacna2d3
uniprot id: A0A803TMZ1
uniprot id: G1KLR0
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

28377:kcng2
gene id: 28377:kcng2
uniprot id: G1K979
names: Subcellular Location Annotation
messages: Membrane

28377:timm17a
gene id: 28377:timm17a
uniprot id: G1KDF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

28377:LOC100560843
gene id: 28377:LOC100560843
uniprot id: R4GBD7
names: Similarity
messages: Belongs to the amidase family.

28377:rnf8
gene id: 28377:rnf8
uniprot id: G1K9T9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CHFR family.
messages: Belongs to the RNF8 family.
messages: E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53BP1 and BRCA1 ionizing radiation-induced foci (IRIF). H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Also catalyzes the formation of 'Lys-48'-linked polyubiquitin chains, leading to degradation of substrate proteins. In addition to its function in damage signaling, also plays a role in higher-order chromatin structure by mediating extensive chromatin decondensation.
messages: Homodimer. Forms a E2-E3 ubiquitin ligase complex composed of the RNF8 homodimer and a E2 heterodimer of UBE2N and UBE2V2.
messages: Nucleus
messages: The FHA domain specifically recognizes and binds ATM-phosphorylated MDC1.

28377:rfx3
gene id: 28377:rfx3
uniprot id: G1KBT1
names: Subcellular Location Annotation
messages: Nucleus

28377:rtn4ip1
gene id: 28377:rtn4ip1
uniprot id: R4GCV2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

28377:kcnj13
gene id: 28377:kcnj13
uniprot id: G1KFD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

28377:ddx3x
gene id: 28377:ddx3x
uniprot id: A0A803T483
uniprot id: A0A803TKA3
uniprot id: G1KUJ3
names: Similarity
messages: Belongs to the DEAD box helicase family.

28377:cfap52
gene id: 28377:cfap52
uniprot id: G1KUC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP52 family.
messages: Cytoplasm
messages: flagellum

28377:wnt3
gene id: 28377:wnt3
uniprot id: G1KSX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

28377:LOC100567051
gene id: 28377:LOC100567051
uniprot id: G1KW33
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:stat4
gene id: 28377:stat4
uniprot id: A0A803TAI1
uniprot id: A0A803TV40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

28377:hip1r
gene id: 28377:hip1r
uniprot id: H9GMU9
names: Similarity
messages: Belongs to the SLA2 family.

28377:fam65b
gene id: 28377:fam65b
uniprot id: A0A803TJL3
uniprot id: G1KAD6
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the RIPOR family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: stereocilium membrane

28377:rbm10
gene id: 28377:rbm10
uniprot id: G1KEN8
names: Subcellular Location Annotation
messages: Nucleus

28377:psma7
gene id: 28377:psma7
uniprot id: G1KS92
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

28377:pdha1
gene id: 28377:pdha1
uniprot id: A0A803TCP6
uniprot id: G1KM26
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

28377:becn1
gene id: 28377:becn1
uniprot id: G1KP93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beclin family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Mitochondrion membrane
messages: Plays a central role in autophagy.
messages: autophagosome
messages: trans-Golgi network membrane

28377:pigp
gene id: 28377:pigp
uniprot id: G1KI81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

28377:slc17a6
gene id: 28377:slc17a6
uniprot id: G1KQR9
names: Subcellular Location Annotation
messages: Membrane

28377:iah1
gene id: 28377:iah1
uniprot id: G1K9P3
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

28377:ppef2
gene id: 28377:ppef2
uniprot id: G1KMR3
names: Similarity
messages: Belongs to the PPP phosphatase family.

28377:eif2b1
gene id: 28377:eif2b1
uniprot id: A0A803THL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

28377:LOC100557674
gene id: 28377:LOC100557674
uniprot id: G1KQY2
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC100553233
gene id: 28377:LOC100553233
uniprot id: G1KJJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:vil1
gene id: 28377:vil1
uniprot id: G1KAJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: filopodium tip
messages: lamellipodium
messages: microvillus
messages: ruffle

28377:fam118a
gene id: 28377:fam118a
uniprot id: G1KQJ3
names: Similarity
messages: Belongs to the FAM118 family.

28377:tbx21
gene id: 28377:tbx21
uniprot id: A0A803TLA0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

28377:nat9
gene id: 28377:nat9
uniprot id: G1KE42
names: Similarity
messages: Belongs to the acetyltransferase family. GNAT subfamily.

28377:eif1
gene id: 28377:eif1
uniprot id: A0A803T3C4
names: Similarity
messages: Belongs to the SUI1 family.

28377:ankh
gene id: 28377:ankh
uniprot id: G1KED7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

28377:gpr183
gene id: 28377:gpr183
uniprot id: G1KUP3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:slc11a2
gene id: 28377:slc11a2
uniprot id: G1KMM6
names: Similarity
messages: Belongs to the NRAMP family.

28377:psmc1
gene id: 28377:psmc1
uniprot id: G1KQ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

28377:prdm1
gene id: 28377:prdm1
uniprot id: G1KE67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

28377:LOC100556245
gene id: 28377:LOC100556245
uniprot id: G1K8A9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

28377:raf1
gene id: 28377:raf1
uniprot id: G1KNI7
uniprot id: R4G9F6
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

28377:cops8
gene id: 28377:cops8
uniprot id: G1KK67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN8 family.
messages: Cytoplasm
messages: Nucleus

28377:clstn2
gene id: 28377:clstn2
uniprot id: A0A803TI45
uniprot id: G1KC08
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

28377:paics
gene id: 28377:paics
uniprot id: G1KIB3
names: Similarity
names: Subunit
messages: Homooctamer.
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily.
messages: In the N-terminal section; belongs to the SAICAR synthetase family.

28377:cse1l
gene id: 28377:cse1l
uniprot id: G1KRY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPO2/CSE1 family.
messages: Cytoplasm

28377:pbx2
gene id: 28377:pbx2
uniprot id: G1KMK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

28377:sema5a
gene id: 28377:sema5a
uniprot id: G1KK42
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:ppp1r16b
gene id: 28377:ppp1r16b
uniprot id: A0A803TNZ5
uniprot id: G1KPN6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28377:map3k13
gene id: 28377:map3k13
uniprot id: G1KH56
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

28377:c2h18orf32
gene id: 28377:c2h18orf32
uniprot id: R4GA25
names: Similarity
messages: Belongs to the UPF0729 family.

28377:alox5
gene id: 28377:alox5
uniprot id: G1KP84
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:vgll3
gene id: 28377:vgll3
uniprot id: G1KP20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.
messages: Nucleus

28377:plpp4
gene id: 28377:plpp4
uniprot id: R4GC42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

28377:LOC100557872
gene id: 28377:LOC100557872
uniprot id: G1KR15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

28377:slc9a9
gene id: 28377:slc9a9
uniprot id: G1KJ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Endosome membrane
messages: Membrane

28377:sgce
gene id: 28377:sgce
uniprot id: A0A803SMH8
uniprot id: G1KP52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan alpha/epsilon family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: Golgi apparatus
messages: dendrite
messages: sarcolemma

28377:hmox1
gene id: 28377:hmox1
uniprot id: G1KSW4
names: Similarity
messages: Belongs to the heme oxygenase family.

28377:thbs2
gene id: 28377:thbs2
uniprot id: G1KBH7
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:LOC100554096
gene id: 28377:LOC100554096
uniprot id: G1KGZ5
names: Similarity
messages: Belongs to the SelWTH family. Selenoprotein T subfamily.

28377:tmem263
gene id: 28377:tmem263
uniprot id: G1KX94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

28377:LOC100554027
gene id: 28377:LOC100554027
uniprot id: G1K8I4
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

28377:mettl4
gene id: 28377:mettl4
uniprot id: G1KI45
names: Similarity
messages: Belongs to the MT-A70-like family.

28377:cer1
gene id: 28377:cer1
uniprot id: G1KUD8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

28377:rrm2b
gene id: 28377:rrm2b
uniprot id: G1KIC0
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

28377:aadac
gene id: 28377:aadac
uniprot id: G1KH99
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

28377:LOC100557659
gene id: 28377:LOC100557659
uniprot id: G1KS43
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

28377:tpk1
gene id: 28377:tpk1
uniprot id: G1KTU3
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

28377:gipc1
gene id: 28377:gipc1
uniprot id: G1KTE8
names: Similarity
messages: Belongs to the GIPC family.

28377:pex3
gene id: 28377:pex3
uniprot id: G1KHF4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PEX19.
messages: Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
messages: Peroxisome membrane

28377:chmp5
gene id: 28377:chmp5
uniprot id: A0A803SKY8
names: Similarity
messages: Belongs to the SNF7 family.

28377:cacna2d1
gene id: 28377:cacna2d1
uniprot id: G1KNB8
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

28377:LOC100559708
gene id: 28377:LOC100559708
uniprot id: G1KID7
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

28377:cmpk2
gene id: 28377:cmpk2
uniprot id: G1KG41
names: Similarity
messages: Belongs to the thymidylate kinase family.

28377:kcnk17
gene id: 28377:kcnk17
uniprot id: G1KA72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

28377:LOC100563798
gene id: 28377:LOC100563798
uniprot id: G1KES1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

28377:tigd1
gene id: 28377:tigd1
uniprot id: G1KUS1
names: Subcellular Location Annotation
messages: Nucleus

28377:tmem63b
gene id: 28377:tmem63b
uniprot id: A0A803SL79
uniprot id: G1K9L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

28377:arv1
gene id: 28377:arv1
uniprot id: G1KAH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane

28377:rimbp2
gene id: 28377:rimbp2
uniprot id: H9GKV9
names: Similarity
messages: Belongs to the RIMBP family.

28377:bsn
gene id: 28377:bsn
uniprot id: G1KVM6
names: Subcellular Location Annotation
messages: Presynaptic active zone

28377:elp4
gene id: 28377:elp4
uniprot id: G1KAE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

28377:alkbh8
gene id: 28377:alkbh8
uniprot id: G1KKM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkB family.
messages: Cytoplasm

28377:LOC100567117
gene id: 28377:LOC100567117
uniprot id: G1KII4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

28377:LOC100558850
gene id: 28377:LOC100558850
uniprot id: A0A803TA47
uniprot id: G1KRD1
names: Similarity
messages: Belongs to the cystatin family.

28377:slc46a2
gene id: 28377:slc46a2
uniprot id: G1KTV3
names: Subcellular Location Annotation
messages: Membrane

28377:elovl7
gene id: 28377:elovl7
uniprot id: G1KIC3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL7 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

28377:msrb2
gene id: 28377:msrb2
uniprot id: R4GCW9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

28377:npbwr2
gene id: 28377:npbwr2
uniprot id: G1KF80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:atp5a1
gene id: 28377:atp5a1
uniprot id: G1KMR9
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

28377:clrn3
gene id: 28377:clrn3
uniprot id: G1KGL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

28377:mrpl27
gene id: 28377:mrpl27
uniprot id: G1KDU3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

28377:pi15
gene id: 28377:pi15
uniprot id: A0A803TEC4
names: Similarity
messages: Belongs to the CRISP family.

28377:kcnh4
gene id: 28377:kcnh4
uniprot id: G1KUL0
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

28377:ilkap
gene id: 28377:ilkap
uniprot id: G1KFI7
names: Similarity
messages: Belongs to the PP2C family.

28377:prkx
gene id: 28377:prkx
uniprot id: G1KEK9
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:nusap1
gene id: 28377:nusap1
uniprot id: G1KC67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUSAP family.
messages: Cytoplasm

28377:olfml2b
gene id: 28377:olfml2b
uniprot id: G1K9A1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:scrn2
gene id: 28377:scrn2
uniprot id: G1KFU7
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

28377:LOC100566729
gene id: 28377:LOC100566729
uniprot id: G1KJ85
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

28377:itih5
gene id: 28377:itih5
uniprot id: G1KDB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

28377:mid1
gene id: 28377:mid1
uniprot id: G1K9B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ohanin/vespryn family.
messages: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
messages: cytoskeleton

28377:rack1
gene id: 28377:rack1
uniprot id: G1KLU0
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

28377:vipr2
gene id: 28377:vipr2
uniprot id: G1KAG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

28377:ormdl1
gene id: 28377:ormdl1
uniprot id: G1KPR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

28377:nsf
gene id: 28377:nsf
uniprot id: A0A803SW71
uniprot id: G1KSV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

28377:b3gnt5
gene id: 28377:b3gnt5
uniprot id: G1KGV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

28377:LOC100554852
gene id: 28377:LOC100554852
uniprot id: G1KSJ6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

28377:cpt1a
gene id: 28377:cpt1a
uniprot id: A0A803SMQ6
uniprot id: G1KPJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

28377:anapc10
gene id: 28377:anapc10
uniprot id: G1KBT5
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

28377:slc30a7
gene id: 28377:slc30a7
uniprot id: G1KBI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Homooligomer.
messages: Membrane
messages: trans-Golgi network membrane

28377:jak2
gene id: 28377:jak2
uniprot id: G1KCE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system
messages: Nucleus

28377:acer2
gene id: 28377:acer2
uniprot id: G1KU81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:cdkn2aipnl
gene id: 28377:cdkn2aipnl
uniprot id: A0A803TK83
names: Similarity
messages: Belongs to the CARF family.

28377:ptprf
gene id: 28377:ptprf
uniprot id: A0A803T423
uniprot id: A0A803TC59
uniprot id: A0A803TIC2
uniprot id: A0A803TLP7
uniprot id: G1KPK7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

28377:ldlrad4
gene id: 28377:ldlrad4
uniprot id: A0A803SSM4
uniprot id: A0A803TEE7
uniprot id: G1KND0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:LOC100562152
gene id: 28377:LOC100562152
uniprot id: G1KDJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

28377:ehd3
gene id: 28377:ehd3
uniprot id: A0A803U1W6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: cilium membrane

28377:arl8b
gene id: 28377:arl8b
uniprot id: A0A803TSE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

28377:ctsc
gene id: 28377:ctsc
uniprot id: G1KQT4
names: Similarity
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

28377:pnpla6
gene id: 28377:pnpla6
uniprot id: A0A803SM78
uniprot id: A0A803SQF2
uniprot id: A0A803T3X5
uniprot id: G1KSE9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28377:ibsp
gene id: 28377:ibsp
uniprot id: G1KML5
names: Function
names: Subcellular Location Annotation
messages: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
messages: Secreted

28377:gkap1
gene id: 28377:gkap1
uniprot id: A0A803TT67
uniprot id: G1K9X6
names: Similarity
messages: Belongs to the GKAP1 family.

28377:osgin2
gene id: 28377:osgin2
uniprot id: G1KK32
names: Similarity
messages: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.

28377:was
gene id: 28377:was
uniprot id: G1KF86
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC100553963
gene id: 28377:LOC100553963
uniprot id: G1KVL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

28377:sfr1
gene id: 28377:sfr1
uniprot id: A0A803U1H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

28377:nmu
gene id: 28377:nmu
uniprot id: R4GCU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NmU family.
messages: Secreted

28377:COX1
gene id: 28377:COX1
uniprot id: B3GSZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

28377:mmrn1
gene id: 28377:mmrn1
uniprot id: G1KNP1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28377:hyal3
gene id: 28377:hyal3
uniprot id: G1KI40
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Early endosome
messages: Endoplasmic reticulum
messages: Endosome
messages: Membrane
messages: Monomer.
messages: acrosome

28377:atp1b1
gene id: 28377:atp1b1
uniprot id: G1KKE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Cell membrane

28377:ptp4a3
gene id: 28377:ptp4a3
uniprot id: G1K8Q4
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

28377:slc1a7
gene id: 28377:slc1a7
uniprot id: G1KI25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

28377:ss18
gene id: 28377:ss18
uniprot id: A0A803TEV3
uniprot id: G1KA52
names: Similarity
messages: Belongs to the SS18 family.

28377:kdr
gene id: 28377:kdr
uniprot id: G1KJF5
names: Subcellular Location Annotation
messages: Membrane

28377:vcan
gene id: 28377:vcan
uniprot id: G1KL45
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

28377:hacd2
gene id: 28377:hacd2
uniprot id: G1KKH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:caskin2
gene id: 28377:caskin2
uniprot id: A0A803TDE5
uniprot id: G1KFM2
names: Subcellular Location Annotation
messages: Cytoplasm

28377:mab21l1
gene id: 28377:mab21l1
uniprot id: G1KCK2
names: Similarity
messages: Belongs to the mab-21 family.

28377:luc7l3
gene id: 28377:luc7l3
uniprot id: A0A803TB08
names: Similarity
messages: Belongs to the Luc7 family.

28377:senp2
gene id: 28377:senp2
uniprot id: A0A803T6U9
names: Similarity
messages: Belongs to the peptidase C48 family.

28377:f3
gene id: 28377:f3
uniprot id: G1KDB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

28377:LOC100553961
gene id: 28377:LOC100553961
uniprot id: R4G9W3
names: Similarity
messages: Belongs to the protein kinase superfamily.

28377:ptch2
gene id: 28377:ptch2
uniprot id: G1KR57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

28377:foxi1
gene id: 28377:foxi1
uniprot id: G1KRV9
names: Subcellular Location Annotation
messages: Nucleus

28377:mapt
gene id: 28377:mapt
uniprot id: A0A803TSA1
names: Subcellular Location Annotation
messages: Membrane
messages: axon
messages: cytoskeleton
messages: cytosol

28377:tmcc3
gene id: 28377:tmcc3
uniprot id: A0A803T1D6
uniprot id: A0A803TJ60
uniprot id: G1KMQ8
names: Similarity
messages: Belongs to the TEX28 family.

28377:tmtc1
gene id: 28377:tmtc1
uniprot id: G1KN82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

28377:LOC100560069
gene id: 28377:LOC100560069
uniprot id: A0A803SS94
uniprot id: G1KH37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Nucleus

28377:fbxo32
gene id: 28377:fbxo32
uniprot id: G1KJ90
names: Subcellular Location Annotation
messages: Nucleus

28377:LOC100551718
gene id: 28377:LOC100551718
uniprot id: G1KKZ6
uniprot id: R4GDH8
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

28377:qtrt1
gene id: 28377:qtrt1
uniprot id: G1KRB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane

28377:nosip
gene id: 28377:nosip
uniprot id: G1KPB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOSIP family.
messages: Cytoplasm
messages: Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity.
messages: Nucleus

28377:gins1
gene id: 28377:gins1
uniprot id: A0A803SNN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

28377:LOC100552272
gene id: 28377:LOC100552272
uniprot id: A0A803TZX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNF-like-inhibitor family.
messages: Secreted

28377:LOC100560433
gene id: 28377:LOC100560433
uniprot id: R4GBM1
names: Similarity
messages: Belongs to the intermediate filament family.

28377:LOC100558797
gene id: 28377:LOC100558797
uniprot id: G1KXN5
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

28377:LOC100568171
gene id: 28377:LOC100568171
uniprot id: G1KJK1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

28377:tmed10
gene id: 28377:tmed10
uniprot id: A0A803SS95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

28377:tbc1d23
gene id: 28377:tbc1d23
uniprot id: G1KL14
names: Subcellular Location Annotation
messages: trans-Golgi network

28377:hoxc10
gene id: 28377:hoxc10
uniprot id: G1KYB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

28377:grn
gene id: 28377:grn
uniprot id: G1KLY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

28377:isca2
gene id: 28377:isca2
uniprot id: A0A803TNP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

28377:cdr2l
gene id: 28377:cdr2l
uniprot id: G1KEX7
names: Similarity
messages: Belongs to the CDR2 family.

28377:syt16
gene id: 28377:syt16
uniprot id: G1KS90
names: Similarity
messages: Belongs to the synaptotagmin family.

28377:tph1
gene id: 28377:tph1
uniprot id: G1K884
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

28377:elavl4
gene id: 28377:elavl4
uniprot id: G1KCV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm
messages: Perikaryon
messages: axon
messages: dendrite
messages: growth cone

28377:acvrl1
gene id: 28377:acvrl1
uniprot id: G1KT96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: Secreted

28377:rpl27a
gene id: 28377:rpl27a
uniprot id: G1KJK2
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

28377:lta4h
gene id: 28377:lta4h
uniprot id: G1KP96
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

28377:mecp2
gene id: 28377:mecp2
uniprot id: G1KME7
names: Subcellular Location Annotation
messages: Nucleus

28377:skp1
gene id: 28377:skp1
uniprot id: A0A803TCY2
uniprot id: G1KB17
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1.

28377:tsnax
gene id: 28377:tsnax
uniprot id: A0A803TBT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

28377:sgpl1
gene id: 28377:sgpl1
uniprot id: G1KI73
names: Similarity
messages: Belongs to the group II decarboxylase family.

28377:mterf4
gene id: 28377:mterf4
uniprot id: G1KA49
names: Similarity
messages: Belongs to the mTERF family.

28377:kif2c
gene id: 28377:kif2c
uniprot id: G1KQF7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

28377:adck1
gene id: 28377:adck1
uniprot id: G1KTR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Secreted

28377:mboat2
gene id: 28377:mboat2
uniprot id: G1KAL2
names: Subcellular Location Annotation
messages: Membrane

28377:htr1b
gene id: 28377:htr1b
uniprot id: G1KD63
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homodimer. Heterodimer with HTR1D.
messages: Membrane

28377:sstr3
gene id: 28377:sstr3
uniprot id: G1KS46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

28377:rcl1
gene id: 28377:rcl1
uniprot id: G1KC43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA.
messages: nucleolus

28377:gjc2
gene id: 28377:gjc2
uniprot id: G1KFU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction