28188:CGC47 RS05180
gene id: 28188:CGC47_RS05180
uniprot id: A0A0B7HH67
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS01965
gene id: 28188:CGC47_RS01965
uniprot id: A0A0B7H5Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

28188:CGC47 RS01905
gene id: 28188:CGC47_RS01905
uniprot id: A0A0B7H0X6
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS02430
gene id: 28188:CGC47_RS02430
uniprot id: A0A0B7H1F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

28188:CGC47 RS01005
gene id: 28188:CGC47_RS01005
uniprot id: A0A0B7HFT8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

28188:CGC47 RS07385
gene id: 28188:CGC47_RS07385
uniprot id: A0A0B7HK08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

28188:CGC47 RS06340
gene id: 28188:CGC47_RS06340
uniprot id: A0A0B7HW59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

28188:CGC47 RS02530
gene id: 28188:CGC47_RS02530
uniprot id: A0A0B7HDG0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

28188:CGC47 RS02965
gene id: 28188:CGC47_RS02965
uniprot id: A0A0B7HBB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

28188:CGC47 RS05615
gene id: 28188:CGC47_RS05615
uniprot id: A0A0B7HDM2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

28188:CGC47 RS05915
gene id: 28188:CGC47_RS05915
uniprot id: A0A0B7HU41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

28188:CGC47 RS08155
gene id: 28188:CGC47_RS08155
uniprot id: A0A0B7HDX3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

28188:CGC47 RS02625
gene id: 28188:CGC47_RS02625
uniprot id: A0A0B7H4E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

28188:CGC47 RS09145
gene id: 28188:CGC47_RS09145
uniprot id: A0A0B7IQD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

28188:CGC47 RS03645
gene id: 28188:CGC47_RS03645
uniprot id: A0A0B7I8A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

28188:CGC47 RS09205
gene id: 28188:CGC47_RS09205
uniprot id: A0A0B7ID35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

28188:CGC47 RS06000
gene id: 28188:CGC47_RS06000
uniprot id: A0A0B7HVE1
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS07100
gene id: 28188:CGC47_RS07100
uniprot id: A0A0B7HH28
names: Similarity
messages: Belongs to the AlaDH/PNT family.

28188:CGC47 RS04510
gene id: 28188:CGC47_RS04510
uniprot id: A0A0B7HRN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

28188:CGC47 RS09180
gene id: 28188:CGC47_RS09180
uniprot id: A0A0B7IQE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

28188:CGC47 RS01835
gene id: 28188:CGC47_RS01835
uniprot id: A0A0B7IG00
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

28188:CGC47 RS09870
gene id: 28188:CGC47_RS09870
uniprot id: A0A0B7HJG1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS06105
gene id: 28188:CGC47_RS06105
uniprot id: A0A250EWA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

28188:CGC47 RS08855
gene id: 28188:CGC47_RS08855
uniprot id: A0A0B7H2W1
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

28188:CGC47 RS04960
gene id: 28188:CGC47_RS04960
uniprot id: A0A0B7HSU7
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS05750
gene id: 28188:CGC47_RS05750
uniprot id: A0A250EYY2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS04230
gene id: 28188:CGC47_RS04230
uniprot id: A0A0B7HLU7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

28188:CGC47 RS04020
gene id: 28188:CGC47_RS04020
uniprot id: A0A0B7HKU0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

28188:CGC47 RS06765
gene id: 28188:CGC47_RS06765
uniprot id: A0A0B7HKW5
names: Similarity
messages: Belongs to the UPF0102 family.

28188:CGC47 RS07045
gene id: 28188:CGC47_RS07045
uniprot id: A0A0B7HKE3
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

28188:CGC47 RS04250
gene id: 28188:CGC47_RS04250
uniprot id: A0A0B7I895
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

28188:CGC47 RS09645
gene id: 28188:CGC47_RS09645
uniprot id: A0A0B7HKA2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

28188:CGC47 RS07905
gene id: 28188:CGC47_RS07905
uniprot id: A0A0B7HLL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

28188:CGC47 RS04220
gene id: 28188:CGC47_RS04220
uniprot id: A0A0B7I3A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

28188:CGC47 RS08375
gene id: 28188:CGC47_RS08375
uniprot id: A0A0B7IFV1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

28188:CGC47 RS03670
gene id: 28188:CGC47_RS03670
uniprot id: A0A0B7HM01
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

28188:CGC47 RS08035
gene id: 28188:CGC47_RS08035
uniprot id: A0A0B7HEG1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

28188:CGC47 RS02925
gene id: 28188:CGC47_RS02925
uniprot id: A0A250EYQ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS04965
gene id: 28188:CGC47_RS04965
uniprot id: A0A0B7HQR7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

28188:CGC47 RS03570
gene id: 28188:CGC47_RS03570
uniprot id: A0A0B7I7U1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

28188:CGC47 RS00665
gene id: 28188:CGC47_RS00665
uniprot id: A0A0B7HEN7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

28188:CGC47 RS04715
gene id: 28188:CGC47_RS04715
uniprot id: A0A0B7IFN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

28188:CGC47 RS00390
gene id: 28188:CGC47_RS00390
uniprot id: A0A0B7H648
names: Similarity
messages: Belongs to the ArsC family.

28188:CGC47 RS08950
gene id: 28188:CGC47_RS08950
uniprot id: A0A0B7H893
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

28188:CGC47 RS04175
gene id: 28188:CGC47_RS04175
uniprot id: A0A0B7IIJ6
names: Similarity
messages: Belongs to the RutC family.

28188:CGC47 RS09275
gene id: 28188:CGC47_RS09275
uniprot id: A0A0B7HBS7
names: Similarity
messages: Belongs to the peptidase S49 family.

28188:CGC47 RS03720
gene id: 28188:CGC47_RS03720
uniprot id: A0A0B7HSB6
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

28188:CGC47 RS08045
gene id: 28188:CGC47_RS08045
uniprot id: A0A0B7H8M4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

28188:CGC47 RS09190
gene id: 28188:CGC47_RS09190
uniprot id: A0A0B7II43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

28188:CGC47 RS09095
gene id: 28188:CGC47_RS09095
uniprot id: A0A0B7ICU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

28188:CGC47 RS03620
gene id: 28188:CGC47_RS03620
uniprot id: A0A250G555
names: Similarity
messages: Belongs to the CarB family.

28188:CGC47 RS07465
gene id: 28188:CGC47_RS07465
uniprot id: A0A250EYY0
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

28188:CGC47 RS05835
gene id: 28188:CGC47_RS05835
uniprot id: A0A250GEX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

28188:CGC47 RS00940
gene id: 28188:CGC47_RS00940
uniprot id: A0A0B7IAW9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

28188:CGC47 RS03520
gene id: 28188:CGC47_RS03520
uniprot id: A0A250EV16
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

28188:CGC47 RS07910
gene id: 28188:CGC47_RS07910
uniprot id: A0A0B7HMM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

28188:CGC47 RS06825
gene id: 28188:CGC47_RS06825
uniprot id: A0A0B7HKR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

28188:CGC47 RS02565
gene id: 28188:CGC47_RS02565
uniprot id: A0A0B7HDJ4
names: Similarity
messages: Belongs to the SusD family.

28188:CGC47 RS09580
gene id: 28188:CGC47_RS09580
uniprot id: A0A0B7HIN4
names: Similarity
messages: Belongs to the aldose epimerase family.

28188:CGC47 RS03255
gene id: 28188:CGC47_RS03255
uniprot id: A0A0B7HL54
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS09535
gene id: 28188:CGC47_RS09535
uniprot id: A0A0B7HLM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

28188:CGC47 RS03695
gene id: 28188:CGC47_RS03695
uniprot id: A0A0B7HM16
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

28188:CGC47 RS09350
gene id: 28188:CGC47_RS09350
uniprot id: A0A0B7IM49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

28188:CGC47 RS09775
gene id: 28188:CGC47_RS09775
uniprot id: A0A0B7HPG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

28188:CGC47 RS04920
gene id: 28188:CGC47_RS04920
uniprot id: A0A0B7HU20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

28188:CGC47 RS03250
gene id: 28188:CGC47_RS03250
uniprot id: A0A0B7HSD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

28188:CGC47 RS10080
gene id: 28188:CGC47_RS10080
uniprot id: A0A0B7HBH9
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

28188:CGC47 RS04485
gene id: 28188:CGC47_RS04485
uniprot id: A0A0B7HUW9
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

28188:CGC47 RS05130
gene id: 28188:CGC47_RS05130
uniprot id: A0A0B7IQ16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

28188:CGC47 RS00645
gene id: 28188:CGC47_RS00645
uniprot id: A0A0B7I909
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

28188:CGC47 RS09220
gene id: 28188:CGC47_RS09220
uniprot id: A0A250G6I1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

28188:CGC47 RS10050
gene id: 28188:CGC47_RS10050
uniprot id: A0A0B7HBE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

28188:CGC47 RS08845
gene id: 28188:CGC47_RS08845
uniprot id: A0A0B7IGR8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

28188:CGC47 RS09875
gene id: 28188:CGC47_RS09875
uniprot id: A0A0B7HPP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

28188:CGC47 RS09000
gene id: 28188:CGC47_RS09000
uniprot id: A0A0B7H9U7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

28188:CGC47 RS08235
gene id: 28188:CGC47_RS08235
uniprot id: A0A0B7H5A7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

28188:CGC47 RS02580
gene id: 28188:CGC47_RS02580
uniprot id: A0A0B7HAU0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

28188:CGC47 RS00475
gene id: 28188:CGC47_RS00475
uniprot id: A0A0B7HG40
names: Similarity
messages: Belongs to the AIR synthase family.

28188:CGC47 RS07755
gene id: 28188:CGC47_RS07755
uniprot id: A0A0B7HN02
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

28188:CGC47 RS00945
gene id: 28188:CGC47_RS00945
uniprot id: A0A0B7HLY4
names: Similarity
messages: Belongs to the DinB family.

28188:CGC47 RS04050
gene id: 28188:CGC47_RS04050
uniprot id: A0A250G4V5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28188:CGC47 RS09395
gene id: 28188:CGC47_RS09395
uniprot id: A0A0B7H3P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

28188:CGC47 RS02915
gene id: 28188:CGC47_RS02915
uniprot id: A0A0B7H8D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

28188:CGC47 RS04375
gene id: 28188:CGC47_RS04375
uniprot id: A0A0B7HK70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

28188:CGC47 RS06040
gene id: 28188:CGC47_RS06040
uniprot id: A0A0B7HVH3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS09010
gene id: 28188:CGC47_RS09010
uniprot id: A0A0B7II97
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

28188:CGC47 RS09260
gene id: 28188:CGC47_RS09260
uniprot id: A0A0B7IQG9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

28188:CGC47 RS02475
gene id: 28188:CGC47_RS02475
uniprot id: A0A0B7H876
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

28188:CGC47 RS00370
gene id: 28188:CGC47_RS00370
uniprot id: A0A0B7I594
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

28188:CGC47 RS01425
gene id: 28188:CGC47_RS01425
uniprot id: A0A0B7H6P0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS08775
gene id: 28188:CGC47_RS08775
uniprot id: A0A250EXM6
names: Similarity
messages: Belongs to the SusD family.

28188:CGC47 RS05460
gene id: 28188:CGC47_RS05460
uniprot id: A0A0B7I6Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

28188:CGC47 RS07150
gene id: 28188:CGC47_RS07150
uniprot id: A0A0B7HFA5
names: Similarity
messages: Belongs to the ArsC family.

28188:CGC47 RS07955
gene id: 28188:CGC47_RS07955
uniprot id: A0A0B7I4A1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

28188:CGC47 RS00230
gene id: 28188:CGC47_RS00230
uniprot id: A0A0B7IK27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

28188:CGC47 RS00995
gene id: 28188:CGC47_RS00995
uniprot id: A0A0B7IAD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

28188:CGC47 RS03135
gene id: 28188:CGC47_RS03135
uniprot id: A0A0B7H7Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

28188:CGC47 RS02295
gene id: 28188:CGC47_RS02295
uniprot id: A0A0B7H410
names: Similarity
messages: Belongs to the citrate synthase family.

28188:CGC47 RS05150
gene id: 28188:CGC47_RS05150
uniprot id: A0A0B7IEK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

28188:CGC47 RS09245
gene id: 28188:CGC47_RS09245
uniprot id: A0A0B7INV4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

28188:CGC47 RS09405
gene id: 28188:CGC47_RS09405
uniprot id: A0A0B7H6B6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

28188:CGC47 RS10650
gene id: 28188:CGC47_RS10650
uniprot id: A0A0B7IMX5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

28188:CGC47 RS07575
gene id: 28188:CGC47_RS07575
uniprot id: A0A250F056
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

28188:CGC47 RS01070
gene id: 28188:CGC47_RS01070
uniprot id: A0A0B7H5A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

28188:CGC47 RS04605
gene id: 28188:CGC47_RS04605
uniprot id: A0A0B7HTJ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

28188:CGC47 RS00425
gene id: 28188:CGC47_RS00425
uniprot id: A0A0B7H0K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

28188:CGC47 RS02820
gene id: 28188:CGC47_RS02820
uniprot id: A0A0B7IR89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

28188:CGC47 RS07665
gene id: 28188:CGC47_RS07665
uniprot id: A0A0B7II18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

28188:CGC47 RS00125
gene id: 28188:CGC47_RS00125
uniprot id: A0A0B7HA44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

28188:CGC47 RS07250
gene id: 28188:CGC47_RS07250
uniprot id: A0A0B7HNS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

28188:CGC47 RS04095
gene id: 28188:CGC47_RS04095
uniprot id: A0A0B7ID36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS07185
gene id: 28188:CGC47_RS07185
uniprot id: A0A0B7H317
names: Similarity
messages: Belongs to the Skp family.

28188:CGC47 RS04520
gene id: 28188:CGC47_RS04520
uniprot id: A0A0B7IDY9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

28188:CGC47 RS05265
gene id: 28188:CGC47_RS05265
uniprot id: A0A0B7IGG7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

28188:CGC47 RS03080
gene id: 28188:CGC47_RS03080
uniprot id: A0A0B7H4F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for cell division and gliding motility.

28188:CGC47 RS09090
gene id: 28188:CGC47_RS09090
uniprot id: A0A0B7IK25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

28188:CGC47 RS02800
gene id: 28188:CGC47_RS02800
uniprot id: A0A0B7HAR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

28188:CGC47 RS05050
gene id: 28188:CGC47_RS05050
uniprot id: A0A0B7IDZ9
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS05125
gene id: 28188:CGC47_RS05125
uniprot id: A0A0B7IJI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

28188:CGC47 RS05490
gene id: 28188:CGC47_RS05490
uniprot id: A0A0B7HHU9
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

28188:CGC47 RS04205
gene id: 28188:CGC47_RS04205
uniprot id: A0A0B7IHQ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

28188:CGC47 RS08530
gene id: 28188:CGC47_RS08530
uniprot id: A0A0B7H5F3
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

28188:CGC47 RS09150
gene id: 28188:CGC47_RS09150
uniprot id: A0A0B7ICM3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

28188:CGC47 RS01440
gene id: 28188:CGC47_RS01440
uniprot id: A0A0B7H985
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS05470
gene id: 28188:CGC47_RS05470
uniprot id: A0A0B7HHX1
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

28188:CGC47 RS01725
gene id: 28188:CGC47_RS01725
uniprot id: A0A250G456
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS02320
gene id: 28188:CGC47_RS02320
uniprot id: A0A0B7H140
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

28188:CGC47 RS00780
gene id: 28188:CGC47_RS00780
uniprot id: A0A0B7IP80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS03700
gene id: 28188:CGC47_RS03700
uniprot id: A0A0B7HTF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

28188:CGC47 RS09670
gene id: 28188:CGC47_RS09670
uniprot id: A0A0B7HKD5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

28188:CGC47 RS08630
gene id: 28188:CGC47_RS08630
uniprot id: A0A0B7H583
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

28188:CGC47 RS04590
gene id: 28188:CGC47_RS04590
uniprot id: A0A0B7HUR2
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

28188:CGC47 RS01825
gene id: 28188:CGC47_RS01825
uniprot id: A0A0B7H2Y8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS03295
gene id: 28188:CGC47_RS03295
uniprot id: A0A0B7HSH8
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

28188:CGC47 RS04215
gene id: 28188:CGC47_RS04215
uniprot id: A0A0B7HLV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

28188:CGC47 RS07035
gene id: 28188:CGC47_RS07035
uniprot id: A0A0B7HH83
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

28188:CGC47 RS00050
gene id: 28188:CGC47_RS00050
uniprot id: A0A0B7HHN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

28188:CGC47 RS03950
gene id: 28188:CGC47_RS03950
uniprot id: A0A0B7HP32
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

28188:CGC47 RS07490
gene id: 28188:CGC47_RS07490
uniprot id: A0A0B7INE4
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS04740
gene id: 28188:CGC47_RS04740
uniprot id: A0A0B7HPB0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28188:CGC47 RS09105
gene id: 28188:CGC47_RS09105
uniprot id: A0A0B7IGI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

28188:CGC47 RS08615
gene id: 28188:CGC47_RS08615
uniprot id: A0A0B7I4T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

28188:CGC47 RS01585
gene id: 28188:CGC47_RS01585
uniprot id: A0A250EU00
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

28188:CGC47 RS02435
gene id: 28188:CGC47_RS02435
uniprot id: A0A0B7ICH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

28188:CGC47 RS09710
gene id: 28188:CGC47_RS09710
uniprot id: A0A0B7HM74
names: Similarity
messages: Belongs to the peptidase S1C family.

28188:CGC47 RS09235
gene id: 28188:CGC47_RS09235
uniprot id: A0A0B7HDM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

28188:CGC47 RS05765
gene id: 28188:CGC47_RS05765
uniprot id: A0A0B7HTW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell membrane

28188:CGC47 RS09990
gene id: 28188:CGC47_RS09990
uniprot id: A0A0B7H772
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

28188:CGC47 RS01995
gene id: 28188:CGC47_RS01995
uniprot id: A0A0B7GZN3
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS09200
gene id: 28188:CGC47_RS09200
uniprot id: A0A0B7HGJ2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

28188:CGC47 RS04880
gene id: 28188:CGC47_RS04880
uniprot id: A0A0B7HMR5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

28188:CGC47 RS05215
gene id: 28188:CGC47_RS05215
uniprot id: A0A0B7HD17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS06680
gene id: 28188:CGC47_RS06680
uniprot id: A0A0B7HL21
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

28188:CGC47 RS10435
gene id: 28188:CGC47_RS10435
uniprot id: A0A0B7H0V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

28188:CGC47 RS06585
gene id: 28188:CGC47_RS06585
uniprot id: A0A0B7HL92
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

28188:CGC47 RS03820
gene id: 28188:CGC47_RS03820
uniprot id: A0A0B7HNJ8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

28188:CGC47 RS07895
gene id: 28188:CGC47_RS07895
uniprot id: A0A0B7HHM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

28188:CGC47 RS07295
gene id: 28188:CGC47_RS07295
uniprot id: A0A0B7HKB4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

28188:CGC47 RS03120
gene id: 28188:CGC47_RS03120
uniprot id: A0A0B7ILH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

28188:CGC47 RS07695
gene id: 28188:CGC47_RS07695
uniprot id: A0A0B7HN37
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

28188:CGC47 RS09700
gene id: 28188:CGC47_RS09700
uniprot id: A0A0B7HKE7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

28188:CGC47 RS08930
gene id: 28188:CGC47_RS08930
uniprot id: A0A0B7H8A8
names: Similarity
messages: Belongs to the arginase family.

28188:CGC47 RS06285
gene id: 28188:CGC47_RS06285
uniprot id: A0A0B7HQZ6
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

28188:CGC47 RS09480
gene id: 28188:CGC47_RS09480
uniprot id: A0A0B7HCV8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

28188:CGC47 RS09960
gene id: 28188:CGC47_RS09960
uniprot id: A0A0B7HJP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

28188:CGC47 RS09100
gene id: 28188:CGC47_RS09100
uniprot id: A0A0B7HFD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

28188:CGC47 RS06530
gene id: 28188:CGC47_RS06530
uniprot id: A0A0B7HNG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

28188:CGC47 RS09210
gene id: 28188:CGC47_RS09210
uniprot id: A0A250GDW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

28188:CGC47 RS05645
gene id: 28188:CGC47_RS05645
uniprot id: A0A0B7HII8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

28188:CGC47 RS09860
gene id: 28188:CGC47_RS09860
uniprot id: A0A250F2A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

28188:CGC47 RS04350
gene id: 28188:CGC47_RS04350
uniprot id: A0A0B7HLJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

28188:CGC47 RS09170
gene id: 28188:CGC47_RS09170
uniprot id: A0A0B7HFJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

28188:CGC47 RS06235
gene id: 28188:CGC47_RS06235
uniprot id: A0A0B7HUU4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

28188:CGC47 RS07640
gene id: 28188:CGC47_RS07640
uniprot id: A0A0B7I3I6
names: Similarity
messages: Belongs to the peptidase S9A family.

28188:CGC47 RS09240
gene id: 28188:CGC47_RS09240
uniprot id: A0A0B7HGQ8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

28188:CGC47 RS08325
gene id: 28188:CGC47_RS08325
uniprot id: A0A0B7HDH3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

28188:CGC47 RS08100
gene id: 28188:CGC47_RS08100
uniprot id: A0A0B7IMI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

28188:CGC47 RS00760
gene id: 28188:CGC47_RS00760
uniprot id: A0A0B7HEH0
names: Similarity
messages: Belongs to the SUI1 family.

28188:CGC47 RS06575
gene id: 28188:CGC47_RS06575
uniprot id: A0A0B7HNB8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

28188:CGC47 RS08505
gene id: 28188:CGC47_RS08505
uniprot id: A0A0B7HK18
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

28188:CGC47 RS04915
gene id: 28188:CGC47_RS04915
uniprot id: A0A0B7HMM9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

28188:CGC47 RS07570
gene id: 28188:CGC47_RS07570
uniprot id: A0A0B7HC48
names: Similarity
messages: Belongs to the DprA/Smf family.

28188:CGC47 RS00910
gene id: 28188:CGC47_RS00910
uniprot id: A0A250G8Z8
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

28188:CGC47 RS03130
gene id: 28188:CGC47_RS03130
uniprot id: A0A0B7H4L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

28188:CGC47 RS01335
gene id: 28188:CGC47_RS01335
uniprot id: A0A0B7H1Q8
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

28188:CGC47 RS03955
gene id: 28188:CGC47_RS03955
uniprot id: A0A250EV68
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

28188:CGC47 RS01975
gene id: 28188:CGC47_RS01975
uniprot id: A0A0B7H5Z0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

28188:CGC47 RS10105
gene id: 28188:CGC47_RS10105
uniprot id: A0A0B7IDH2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

28188:CGC47 RS07355
gene id: 28188:CGC47_RS07355
uniprot id: A0A0B7I7N6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

28188:CGC47 RS00365
gene id: 28188:CGC47_RS00365
uniprot id: A0A0B7H145
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

28188:CGC47 RS09075
gene id: 28188:CGC47_RS09075
uniprot id: A0A0B7IIC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

28188:CGC47 RS01960
gene id: 28188:CGC47_RS01960
uniprot id: A0A0B7I6J3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

28188:CGC47 RS00595
gene id: 28188:CGC47_RS00595
uniprot id: A0A0B7H9U8
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS09770
gene id: 28188:CGC47_RS09770
uniprot id: A0A0B7HQH6
names: Similarity
messages: Belongs to the UPF0173 family.

28188:CGC47 RS08435
gene id: 28188:CGC47_RS08435
uniprot id: A0A0B7IDY2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS05190
gene id: 28188:CGC47_RS05190
uniprot id: A0A0B7HF12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

28188:CGC47 RS08465
gene id: 28188:CGC47_RS08465
uniprot id: A0A0B7IS41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

28188:CGC47 RS10075
gene id: 28188:CGC47_RS10075
uniprot id: A0A0B7HCH7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

28188:CGC47 RS04990
gene id: 28188:CGC47_RS04990
uniprot id: A0A0B7HSS0
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS04745
gene id: 28188:CGC47_RS04745
uniprot id: A0A0B7HR86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

28188:CGC47 RS09615
gene id: 28188:CGC47_RS09615
uniprot id: A0A0B7IFC3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS03200
gene id: 28188:CGC47_RS03200
uniprot id: A0A0B7H9H9
names: Similarity
messages: Belongs to the alkaline phosphatase family.

28188:CGC47 RS01400
gene id: 28188:CGC47_RS01400
uniprot id: A0A0B7H8G9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

28188:CGC47 RS10000
gene id: 28188:CGC47_RS10000
uniprot id: A0A250GCL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

28188:CGC47 RS09250
gene id: 28188:CGC47_RS09250
uniprot id: A0A0B7HAR9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

28188:CGC47 RS02620
gene id: 28188:CGC47_RS02620
uniprot id: A0A0B7H2M5
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS08095
gene id: 28188:CGC47_RS08095
uniprot id: A0A0B7IH82
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

28188:CGC47 RS01925
gene id: 28188:CGC47_RS01925
uniprot id: A0A0B7H615
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

28188:CGC47 RS04360
gene id: 28188:CGC47_RS04360
uniprot id: A0A0B7HQJ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28188:CGC47 RS03430
gene id: 28188:CGC47_RS03430
uniprot id: A0A0B7HMX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS08850
gene id: 28188:CGC47_RS08850
uniprot id: A0A0B7H5X4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

28188:CGC47 RS04405
gene id: 28188:CGC47_RS04405
uniprot id: A0A0B7HK43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

28188:CGC47 RS05910
gene id: 28188:CGC47_RS05910
uniprot id: A0A0B7HS27
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

28188:CGC47 RS09160
gene id: 28188:CGC47_RS09160
uniprot id: A0A0B7HGF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

28188:CGC47 RS00010
gene id: 28188:CGC47_RS00010
uniprot id: A0A0B7ILA6
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

28188:CGC47 RS04235
gene id: 28188:CGC47_RS04235
uniprot id: A0A0B7I7W7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

28188:CGC47 RS09070
gene id: 28188:CGC47_RS09070
uniprot id: A0A250EXT7
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

28188:CGC47 RS06310
gene id: 28188:CGC47_RS06310
uniprot id: A0A0B7HW49
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS04665
gene id: 28188:CGC47_RS04665
uniprot id: A0A0B7HRB7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

28188:CGC47 RS06570
gene id: 28188:CGC47_RS06570
uniprot id: A0A250EZU5
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS00295
gene id: 28188:CGC47_RS00295
uniprot id: A0A0B7H640
names: Similarity
messages: Belongs to the SusD family.

28188:CGC47 RS08370
gene id: 28188:CGC47_RS08370
uniprot id: A0A0B7HEV7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

28188:CGC47 RS10230
gene id: 28188:CGC47_RS10230
uniprot id: A0A0B7H7Y6
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS04995
gene id: 28188:CGC47_RS04995
uniprot id: A0A0B7HNU9
names: Similarity
messages: Belongs to the cytochrome c-552 family.

28188:CGC47 RS08595
gene id: 28188:CGC47_RS08595
uniprot id: A0A0B7IS15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

28188:CGC47 RS04090
gene id: 28188:CGC47_RS04090
uniprot id: A0A250EV79
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

28188:CGC47 RS07830
gene id: 28188:CGC47_RS07830
uniprot id: A0A0B7IQW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

28188:CGC47 RS02570
gene id: 28188:CGC47_RS02570
uniprot id: A0A0B7HCM2
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

28188:CGC47 RS01065
gene id: 28188:CGC47_RS01065
uniprot id: A0A0B7H173
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

28188:CGC47 RS05445
gene id: 28188:CGC47_RS05445
uniprot id: A0A0B7HI01
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

28188:CGC47 RS07030
gene id: 28188:CGC47_RS07030
uniprot id: A0A0B7IEZ8
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS01660
gene id: 28188:CGC47_RS01660
uniprot id: A0A0B7H807
names: Similarity
messages: Belongs to the peptidase C40 family.

28188:CGC47 RS04735
gene id: 28188:CGC47_RS04735
uniprot id: A0A0B7HN08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

28188:CGC47 RS06200
gene id: 28188:CGC47_RS06200
uniprot id: A0A0B7IG78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

28188:CGC47 RS09375
gene id: 28188:CGC47_RS09375
uniprot id: A0A0B7HAX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

28188:CGC47 RS03445
gene id: 28188:CGC47_RS03445
uniprot id: A0A0B7HLJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

28188:CGC47 RS00320
gene id: 28188:CGC47_RS00320
uniprot id: A0A250G6S9
names: Similarity
messages: Belongs to the Skp family.

28188:CGC47 RS00535
gene id: 28188:CGC47_RS00535
uniprot id: A0A0B7H9Z1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS00930
gene id: 28188:CGC47_RS00930
uniprot id: A0A0B7HGZ3
names: Similarity
messages: Belongs to the peptidase C40 family.

28188:CGC47 RS08040
gene id: 28188:CGC47_RS08040
uniprot id: A0A0B7IH42
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

28188:CGC47 RS04370
gene id: 28188:CGC47_RS04370
uniprot id: A0A0B7HNA9
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

28188:CGC47 RS02920
gene id: 28188:CGC47_RS02920
uniprot id: A0A0B7I365
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

28188:CGC47 RS07555
gene id: 28188:CGC47_RS07555
uniprot id: A0A0B7I6B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

28188:CGC47 RS10645
gene id: 28188:CGC47_RS10645
uniprot id: A0A0B7HHF9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

28188:CGC47 RS05575
gene id: 28188:CGC47_RS05575
uniprot id: A0A0B7HIN9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

28188:CGC47 RS04450
gene id: 28188:CGC47_RS04450
uniprot id: A0A0B7HN35
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

28188:CGC47 RS06565
gene id: 28188:CGC47_RS06565
uniprot id: A0A0B7HI86
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

28188:CGC47 RS06185
gene id: 28188:CGC47_RS06185
uniprot id: A0A0B7HUQ1
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS10040
gene id: 28188:CGC47_RS10040
uniprot id: A0A0B7H7B1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

28188:CGC47 RS06980
gene id: 28188:CGC47_RS06980
uniprot id: A0A0B7HHE4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

28188:CGC47 RS01380
gene id: 28188:CGC47_RS01380
uniprot id: A0A0B7H6R0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

28188:CGC47 RS05745
gene id: 28188:CGC47_RS05745
uniprot id: A0A0B7HPV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

28188:CGC47 RS07900
gene id: 28188:CGC47_RS07900
uniprot id: A0A0B7HGB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

28188:CGC47 RS01305
gene id: 28188:CGC47_RS01305
uniprot id: A0A0B7H1P8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28188:CGC47 RS02445
gene id: 28188:CGC47_RS02445
uniprot id: A0A0B7IE77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

28188:CGC47 RS03480
gene id: 28188:CGC47_RS03480
uniprot id: A0A0B7HPS9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

28188:CGC47 RS09940
gene id: 28188:CGC47_RS09940
uniprot id: A0A0B7HKX9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

28188:CGC47 RS05795
gene id: 28188:CGC47_RS05795
uniprot id: A0A0B7HV26
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

28188:CGC47 RS02940
gene id: 28188:CGC47_RS02940
uniprot id: A0A0B7HBD4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

28188:CGC47 RS01985
gene id: 28188:CGC47_RS01985
uniprot id: A0A0B7H6S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

28188:CGC47 RS09760
gene id: 28188:CGC47_RS09760
uniprot id: A0A0B7HPF0
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

28188:CGC47 RS03690
gene id: 28188:CGC47_RS03690
uniprot id: A0A0B7HQ96
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

28188:CGC47 RS07520
gene id: 28188:CGC47_RS07520
uniprot id: A0A250EYX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

28188:CGC47 RS00240
gene id: 28188:CGC47_RS00240
uniprot id: A0A0B7H7B4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

28188:CGC47 RS09125
gene id: 28188:CGC47_RS09125
uniprot id: A0A0B7HFF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

28188:CGC47 RS07885
gene id: 28188:CGC47_RS07885
uniprot id: A0A0B7HMP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

28188:CGC47 RS00550
gene id: 28188:CGC47_RS00550
uniprot id: A0A0B7HVQ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

28188:CGC47 RS01160
gene id: 28188:CGC47_RS01160
uniprot id: A0A0B7IJN4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

28188:CGC47 RS08720
gene id: 28188:CGC47_RS08720
uniprot id: A0A0B7H8Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

28188:CGC47 RS07610
gene id: 28188:CGC47_RS07610
uniprot id: A0A0B7HI68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

28188:CGC47 RS08590
gene id: 28188:CGC47_RS08590
uniprot id: A0A0B7HB19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

28188:CGC47 RS08705
gene id: 28188:CGC47_RS08705
uniprot id: A0A0B7H8X5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

28188:CGC47 RS07085
gene id: 28188:CGC47_RS07085
uniprot id: A0A250EWX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

28188:CGC47 RS05395
gene id: 28188:CGC47_RS05395
uniprot id: A0A0B7HJ52
names: Similarity
messages: Belongs to the peptidase C1 family.

28188:CGC47 RS09620
gene id: 28188:CGC47_RS09620
uniprot id: A0A0B7HIU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

28188:CGC47 RS00220
gene id: 28188:CGC47_RS00220
uniprot id: A0A0B7IDU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

28188:CGC47 RS05195
gene id: 28188:CGC47_RS05195
uniprot id: A0A0B7HF07
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

28188:CGC47 RS10565
gene id: 28188:CGC47_RS10565
uniprot id: A0A0B7IF51
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS03060
gene id: 28188:CGC47_RS03060
uniprot id: A0A0B7HZ23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

28188:CGC47 RS08215
gene id: 28188:CGC47_RS08215
uniprot id: A0A0B7H7S0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

28188:CGC47 RS00160
gene id: 28188:CGC47_RS00160
uniprot id: A0A0B7HBX9
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

28188:CGC47 RS02960
gene id: 28188:CGC47_RS02960
uniprot id: A0A0B7HE36
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

28188:CGC47 RS01800
gene id: 28188:CGC47_RS01800
uniprot id: A0A0B7H623
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

28188:CGC47 RS10470
gene id: 28188:CGC47_RS10470
uniprot id: A0A0B7HC10
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

28188:CGC47 RS04415
gene id: 28188:CGC47_RS04415
uniprot id: A0A0B7IE68
names: Similarity
messages: Belongs to the ParB family.

28188:CGC47 RS05355
gene id: 28188:CGC47_RS05355
uniprot id: A0A0B7H9P3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

28188:CGC47 RS07855
gene id: 28188:CGC47_RS07855
uniprot id: A0A0B7HHR2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS01310
gene id: 28188:CGC47_RS01310
uniprot id: A0A0B7HWR3
names: Similarity
messages: Belongs to the Dps family.

28188:CGC47 RS09020
gene id: 28188:CGC47_RS09020
uniprot id: A0A0B7IIH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

28188:CGC47 RS00795
gene id: 28188:CGC47_RS00795
uniprot id: A0A0B7HL96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

28188:CGC47 RS00325
gene id: 28188:CGC47_RS00325
uniprot id: A0A0B7ILK5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

28188:CGC47 RS05840
gene id: 28188:CGC47_RS05840
uniprot id: A0A0B7HQ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

28188:CGC47 RS01180
gene id: 28188:CGC47_RS01180
uniprot id: A0A0B7H0Q9
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

28188:CGC47 RS00335
gene id: 28188:CGC47_RS00335
uniprot id: A0A0B7H1C2
names: Similarity
messages: Belongs to the UPF0246 family.

28188:CGC47 RS02735
gene id: 28188:CGC47_RS02735
uniprot id: A0A0B7H5V7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS05350
gene id: 28188:CGC47_RS05350
uniprot id: A0A0B7H4M3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

28188:CGC47 RS03745
gene id: 28188:CGC47_RS03745
uniprot id: A0A0B7HSC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

28188:CGC47 RS04060
gene id: 28188:CGC47_RS04060
uniprot id: A0A0B7ID49
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS08190
gene id: 28188:CGC47_RS08190
uniprot id: A0A0B7H539
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

28188:CGC47 RS09880
gene id: 28188:CGC47_RS09880
uniprot id: A0A0B7HPQ2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

28188:CGC47 RS08125
gene id: 28188:CGC47_RS08125
uniprot id: A0A0B7H8W0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

28188:CGC47 RS04400
gene id: 28188:CGC47_RS04400
uniprot id: A0A0B7HN84
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

28188:CGC47 RS04105
gene id: 28188:CGC47_RS04105
uniprot id: A0A0B7HM17
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

28188:CGC47 RS01830
gene id: 28188:CGC47_RS01830
uniprot id: A0A250EU23
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS03730
gene id: 28188:CGC47_RS03730
uniprot id: A0A0B7HTG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

28188:CGC47 RS05760
gene id: 28188:CGC47_RS05760
uniprot id: A0A250EW56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

28188:CGC47 RS08105
gene id: 28188:CGC47_RS08105
uniprot id: A0A0B7HDS6
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

28188:CGC47 RS10095
gene id: 28188:CGC47_RS10095
uniprot id: A0A0B7H7F6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

28188:CGC47 RS05175
gene id: 28188:CGC47_RS05175
uniprot id: A0A0B7HC18
names: Subcellular Location Annotation
messages: Mitochondrion

28188:CGC47 RS06095
gene id: 28188:CGC47_RS06095
uniprot id: A0A0B7HP88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

28188:CGC47 RS00270
gene id: 28188:CGC47_RS00270
uniprot id: A0A0B7ILQ7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

28188:CGC47 RS06510
gene id: 28188:CGC47_RS06510
uniprot id: A0A0B7HLF6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

28188:CGC47 RS09130
gene id: 28188:CGC47_RS09130
uniprot id: A0A0B7ID75
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

28188:CGC47 RS06725
gene id: 28188:CGC47_RS06725
uniprot id: A0A0B7HPA2
names: Similarity
messages: Belongs to the SCO1/2 family.

28188:CGC47 RS03630
gene id: 28188:CGC47_RS03630
uniprot id: A0A0B7IIM2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

28188:CGC47 RS04310
gene id: 28188:CGC47_RS04310
uniprot id: A0A0B7HNJ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

28188:CGC47 RS08050
gene id: 28188:CGC47_RS08050
uniprot id: A0A0B7HBN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

28188:CGC47 RS01970
gene id: 28188:CGC47_RS01970
uniprot id: A0A0B7I8Y5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

28188:CGC47 RS06245
gene id: 28188:CGC47_RS06245
uniprot id: A0A0B7HPL3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

28188:CGC47 RS07315
gene id: 28188:CGC47_RS07315
uniprot id: A0A250EWX0
names: Similarity
messages: Belongs to the asparaginase 1 family.

28188:CGC47 RS06810
gene id: 28188:CGC47_RS06810
uniprot id: A0A0B7HHQ6
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

28188:CGC47 RS04075
gene id: 28188:CGC47_RS04075
uniprot id: A0A0B7IR65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

28188:CGC47 RS09725
gene id: 28188:CGC47_RS09725
uniprot id: A0A0B7HQD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

28188:CGC47 RS05015
gene id: 28188:CGC47_RS05015
uniprot id: A0A0B7IJN1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

28188:CGC47 RS02550
gene id: 28188:CGC47_RS02550
uniprot id: A0A0B7HCJ3
names: Similarity
messages: Belongs to the fabD family.

28188:CGC47 RS09225
gene id: 28188:CGC47_RS09225
uniprot id: A0A0B7ICJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

28188:CGC47 RS09575
gene id: 28188:CGC47_RS09575
uniprot id: A0A0B7HPY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS10685
gene id: 28188:CGC47_RS10685
uniprot id: A0A0B7HHJ1
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

28188:CGC47 RS09885
gene id: 28188:CGC47_RS09885
uniprot id: A0A0B7HPQ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS05790
gene id: 28188:CGC47_RS05790
uniprot id: A0A0B7HNQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

28188:CGC47 RS06230
gene id: 28188:CGC47_RS06230
uniprot id: A0A0B7HSS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

28188:CGC47 RS08550
gene id: 28188:CGC47_RS08550
uniprot id: A0A0B7HB52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

28188:CGC47 RS09140
gene id: 28188:CGC47_RS09140
uniprot id: A0A0B7ID67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

28188:CGC47 RS07670
gene id: 28188:CGC47_RS07670
uniprot id: A0A0B7HJT9
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

28188:CGC47 RS04290
gene id: 28188:CGC47_RS04290
uniprot id: A0A0B7HKG2
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

28188:CGC47 RS06730
gene id: 28188:CGC47_RS06730
uniprot id: A0A0B7HKY4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS05185
gene id: 28188:CGC47_RS05185
uniprot id: A0A0B7HI58
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS04025
gene id: 28188:CGC47_RS04025
uniprot id: A0A250G801
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

28188:CGC47 RS00450
gene id: 28188:CGC47_RS00450
uniprot id: A0A0B7H4C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

28188:CGC47 RS05370
gene id: 28188:CGC47_RS05370
uniprot id: A0A0B7HEB4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

28188:CGC47 RS09185
gene id: 28188:CGC47_RS09185
uniprot id: A0A0B7II76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

28188:CGC47 RS00725
gene id: 28188:CGC47_RS00725
uniprot id: A0A0B7HCK0
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS04610
gene id: 28188:CGC47_RS04610
uniprot id: A0A0B7HPK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

28188:CGC47 RS03540
gene id: 28188:CGC47_RS03540
uniprot id: A0A0B7HS00
names: Similarity
messages: Belongs to the IMPACT family.

28188:CGC47 RS03000
gene id: 28188:CGC47_RS03000
uniprot id: A0A0B7H906
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

28188:CGC47 RS09560
gene id: 28188:CGC47_RS09560
uniprot id: A0A250EY28
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS03145
gene id: 28188:CGC47_RS03145
uniprot id: A0A0B7H7Q5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

28188:CGC47 RS03855
gene id: 28188:CGC47_RS03855
uniprot id: A0A0B7HM95
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS03550
gene id: 28188:CGC47_RS03550
uniprot id: A0A0B7HS37
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

28188:CGC47 RS01735
gene id: 28188:CGC47_RS01735
uniprot id: A0A0B7H666
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

28188:CGC47 RS05410
gene id: 28188:CGC47_RS05410
uniprot id: A0A0B7I6V8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

28188:CGC47 RS10350
gene id: 28188:CGC47_RS10350
uniprot id: A0A0B7I6Q7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS04615
gene id: 28188:CGC47_RS04615
uniprot id: A0A0B7IDE1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

28188:CGC47 RS07660
gene id: 28188:CGC47_RS07660
uniprot id: A0A0B7HI43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

28188:CGC47 RS07600
gene id: 28188:CGC47_RS07600
uniprot id: A0A0B7HC22
names: Similarity
messages: Belongs to the peptidase S8 family.

28188:CGC47 RS04535
gene id: 28188:CGC47_RS04535
uniprot id: A0A0B7II08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

28188:CGC47 RS07380
gene id: 28188:CGC47_RS07380
uniprot id: A0A0B7HM87
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS07020
gene id: 28188:CGC47_RS07020
uniprot id: A0A0B7ICX3
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS07890
gene id: 28188:CGC47_RS07890
uniprot id: A0A0B7IP03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28188:CGC47 RS02665
gene id: 28188:CGC47_RS02665
uniprot id: A0A250EUI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

28188:CGC47 RS09060
gene id: 28188:CGC47_RS09060
uniprot id: A0A0B7HAN3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

28188:CGC47 RS05170
gene id: 28188:CGC47_RS05170
uniprot id: A0A0B7HC23
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

28188:CGC47 RS05450
gene id: 28188:CGC47_RS05450
uniprot id: A0A0B7HIZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

28188:CGC47 RS04120
gene id: 28188:CGC47_RS04120
uniprot id: A0A0B7HNW5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

28188:CGC47 RS04585
gene id: 28188:CGC47_RS04585
uniprot id: A0A0B7INC0
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

28188:CGC47 RS08635
gene id: 28188:CGC47_RS08635
uniprot id: A0A250F0W3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

28188:CGC47 RS03350
gene id: 28188:CGC47_RS03350
uniprot id: A0A0B7I517
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28188:CGC47 RS06155
gene id: 28188:CGC47_RS06155
uniprot id: A0A0B7HUM5
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS07530
gene id: 28188:CGC47_RS07530
uniprot id: A0A250F1N9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

28188:CGC47 RS03800
gene id: 28188:CGC47_RS03800
uniprot id: A0A0B7HSF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

28188:CGC47 RS09025
gene id: 28188:CGC47_RS09025
uniprot id: A0A0B7H849
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

28188:CGC47 RS03090
gene id: 28188:CGC47_RS03090
uniprot id: A0A0B7H7L0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

28188:CGC47 RS09230
gene id: 28188:CGC47_RS09230
uniprot id: A0A0B7II52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

28188:CGC47 RS09005
gene id: 28188:CGC47_RS09005
uniprot id: A0A0B7H526
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

28188:CGC47 RS10310
gene id: 28188:CGC47_RS10310
uniprot id: A0A250EYI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

28188:CGC47 RS09270
gene id: 28188:CGC47_RS09270
uniprot id: A0A0B7INV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28188:CGC47 RS07730
gene id: 28188:CGC47_RS07730
uniprot id: A0A250EZ36
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS09950
gene id: 28188:CGC47_RS09950
uniprot id: A0A0B7ILW1
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

28188:CGC47 RS05415
gene id: 28188:CGC47_RS05415
uniprot id: A0A0B7I0W6
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS10675
gene id: 28188:CGC47_RS10675
uniprot id: A0A0B7IL94
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS09120
gene id: 28188:CGC47_RS09120
uniprot id: A0A0B7IK38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

28188:CGC47 RS06080
gene id: 28188:CGC47_RS06080
uniprot id: A0A0B7HP75
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS05060
gene id: 28188:CGC47_RS05060
uniprot id: A0A0B7IJH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

28188:CGC47 RS07200
gene id: 28188:CGC47_RS07200
uniprot id: A0A0B7H5M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

28188:CGC47 RS10425
gene id: 28188:CGC47_RS10425
uniprot id: A0A250F2C9
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

28188:CGC47 RS05510
gene id: 28188:CGC47_RS05510
uniprot id: A0A0B7HDX6
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

28188:CGC47 RS00210
gene id: 28188:CGC47_RS00210
uniprot id: A0A0B7HD32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

28188:CGC47 RS07160
gene id: 28188:CGC47_RS07160
uniprot id: A0A250EYX1
names: Similarity
messages: Belongs to the DtxR/MntR family.

28188:CGC47 RS09265
gene id: 28188:CGC47_RS09265
uniprot id: A0A0B7HGS5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS07560
gene id: 28188:CGC47_RS07560
uniprot id: A0A0B7H9Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

28188:CGC47 RS02275
gene id: 28188:CGC47_RS02275
uniprot id: A0A0B7H5P9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

28188:CGC47 RS05065
gene id: 28188:CGC47_RS05065
uniprot id: A0A0B7H4W1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28188:CGC47 RS00625
gene id: 28188:CGC47_RS00625
uniprot id: A0A0B7H9S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

28188:CGC47 RS02650
gene id: 28188:CGC47_RS02650
uniprot id: A0A0B7IL82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

28188:CGC47 RS01015
gene id: 28188:CGC47_RS01015
uniprot id: A0A0B7HL27
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS02690
gene id: 28188:CGC47_RS02690
uniprot id: A0A0B7H8U9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

28188:CGC47 RS06955
gene id: 28188:CGC47_RS06955
uniprot id: A0A0B7HFU1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

28188:CGC47 RS09800
gene id: 28188:CGC47_RS09800
uniprot id: A0A0B7IK96
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28188:CGC47 RS07965
gene id: 28188:CGC47_RS07965
uniprot id: A0A0B7HLF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

28188:CGC47 RS00400
gene id: 28188:CGC47_RS00400
uniprot id: A0A0B7I779
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28188:CGC47 RS09390
gene id: 28188:CGC47_RS09390
uniprot id: A0A250F0S0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

28188:CGC47 RS01625
gene id: 28188:CGC47_RS01625
uniprot id: A0A0B7H5L5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

28188:CGC47 RS00655
gene id: 28188:CGC47_RS00655
uniprot id: A0A0B7I6R1
names: Similarity
messages: Belongs to the HSP15 family.

28188:CGC47 RS08355
gene id: 28188:CGC47_RS08355
uniprot id: A0A0B7ILK7
names: Similarity
messages: Belongs to the pyruvate kinase family.

28188:CGC47 RS04885
gene id: 28188:CGC47_RS04885
uniprot id: A0A0B7IEC5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

28188:CGC47 RS01610
gene id: 28188:CGC47_RS01610
uniprot id: A0A0B7H6H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

28188:CGC47 RS08905
gene id: 28188:CGC47_RS08905
uniprot id: A0A0B7H6A9
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

28188:CGC47 RS02980
gene id: 28188:CGC47_RS02980
uniprot id: A0A0B7H878
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS03400
gene id: 28188:CGC47_RS03400
uniprot id: A0A0B7HSU1
names: Similarity
messages: Belongs to the transglycosylase Slt family.

28188:CGC47 RS04925
gene id: 28188:CGC47_RS04925
uniprot id: A0A0B7I8L7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

28188:CGC47 RS03365
gene id: 28188:CGC47_RS03365
uniprot id: A0A0B7HPL1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

28188:CGC47 RS01665
gene id: 28188:CGC47_RS01665
uniprot id: A0A0B7H3U6
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS00610
gene id: 28188:CGC47_RS00610
uniprot id: A0A0B7HFS1
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

28188:CGC47 RS04065
gene id: 28188:CGC47_RS04065
uniprot id: A0A0B7IDL8
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS03330
gene id: 28188:CGC47_RS03330
uniprot id: A0A0B7HSL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

28188:CGC47 RS00720
gene id: 28188:CGC47_RS00720
uniprot id: A0A0B7H9J2
names: Similarity
messages: Belongs to the pirin family.

28188:CGC47 RS07615
gene id: 28188:CGC47_RS07615
uniprot id: A0A0B7IJ48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

28188:CGC47 RS04135
gene id: 28188:CGC47_RS04135
uniprot id: A0A0B7HRX6
names: Similarity
messages: Belongs to the nitroreductase family.

28188:CGC47 RS01000
gene id: 28188:CGC47_RS01000
uniprot id: A0A0B7HM29
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

28188:CGC47 RS06210
gene id: 28188:CGC47_RS06210
uniprot id: A0A250EYX3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS01115
gene id: 28188:CGC47_RS01115
uniprot id: A0A0B7H5Q5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

28188:CGC47 RS08605
gene id: 28188:CGC47_RS08605
uniprot id: A0A0B7H597
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

28188:CGC47 RS08440
gene id: 28188:CGC47_RS08440
uniprot id: A0A0B7HJX6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

28188:CGC47 RS08610
gene id: 28188:CGC47_RS08610
uniprot id: A0A0B7I0E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

28188:CGC47 RS09065
gene id: 28188:CGC47_RS09065
uniprot id: A0A0B7H5K6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

28188:CGC47 RS05240
gene id: 28188:CGC47_RS05240
uniprot id: A0A0B7HEQ9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

28188:CGC47 RS08620
gene id: 28188:CGC47_RS08620
uniprot id: A0A0B7HA09
names: Similarity
messages: Belongs to the universal stress protein A family.

28188:CGC47 RS06525
gene id: 28188:CGC47_RS06525
uniprot id: A0A0B7HIB4
names: Similarity
messages: Belongs to the SusD family.

28188:CGC47 RS00315
gene id: 28188:CGC47_RS00315
uniprot id: A0A0B7H4B5
names: Similarity
messages: Belongs to the Skp family.

28188:CGC47 RS09135
gene id: 28188:CGC47_RS09135
uniprot id: A0A0B7IQC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

28188:CGC47 RS02325
gene id: 28188:CGC47_RS02325
uniprot id: A0A250EXJ7
names: Similarity
messages: Belongs to the aspartokinase family.

28188:CGC47 RS04380
gene id: 28188:CGC47_RS04380
uniprot id: A0A250EYK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

28188:CGC47 RS01730
gene id: 28188:CGC47_RS01730
uniprot id: A0A250EU15
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.

28188:CGC47 RS07300
gene id: 28188:CGC47_RS07300
uniprot id: A0A0B7HIM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

28188:CGC47 RS00575
gene id: 28188:CGC47_RS00575
uniprot id: A0A0B7HAT1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

28188:CGC47 RS07505
gene id: 28188:CGC47_RS07505
uniprot id: A0A0B7HA71
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

28188:CGC47 RS04225
gene id: 28188:CGC47_RS04225
uniprot id: A0A0B7HRR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

28188:CGC47 RS01340
gene id: 28188:CGC47_RS01340
uniprot id: A0A0B7H167
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

28188:CGC47 RS00225
gene id: 28188:CGC47_RS00225
uniprot id: A0A250G6C0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

28188:CGC47 RS03575
gene id: 28188:CGC47_RS03575
uniprot id: A0A0B7IBD5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

28188:CGC47 RS07025
gene id: 28188:CGC47_RS07025
uniprot id: A0A0B7IEA9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28188:CGC47 RS07500
gene id: 28188:CGC47_RS07500
uniprot id: A0A0B7I4A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

28188:CGC47 RS09195
gene id: 28188:CGC47_RS09195
uniprot id: A0A0B7ICK5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

28188:CGC47 RS04435
gene id: 28188:CGC47_RS04435
uniprot id: A0A0B7HK06
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

28188:CGC47 RS06590
gene id: 28188:CGC47_RS06590
uniprot id: A0A0B7HI67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

28188:CGC47 RS06060
gene id: 28188:CGC47_RS06060
uniprot id: A0A0B7HP54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

28188:CGC47 RS07400
gene id: 28188:CGC47_RS07400
uniprot id: A0A0B7HIA0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

28188:CGC47 RS02045
gene id: 28188:CGC47_RS02045
uniprot id: A0A0B7H736
names: Similarity
messages: Belongs to the catalase family.

28188:CGC47 RS02995
gene id: 28188:CGC47_RS02995
uniprot id: A0A0B7IE72
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

28188:CGC47 RS01130
gene id: 28188:CGC47_RS01130
uniprot id: A0A0B7H0S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

28188:CGC47 RS07750
gene id: 28188:CGC47_RS07750
uniprot id: A0A0B7HLW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

28188:CGC47 RS09175
gene id: 28188:CGC47_RS09175
uniprot id: A0A0B7HAJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

28188:CGC47 RS06370
gene id: 28188:CGC47_RS06370
uniprot id: A0A0B7HW68
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

28188:CGC47 RS02485
gene id: 28188:CGC47_RS02485
uniprot id: A0A0B7HAK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

28188:CGC47 RS08875
gene id: 28188:CGC47_RS08875
uniprot id: A0A0B7H684
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

28188:CGC47 RS02405
gene id: 28188:CGC47_RS02405
uniprot id: A0A0B7H703
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS06805
gene id: 28188:CGC47_RS06805
uniprot id: A0A0B7HJ23
names: Similarity
messages: Belongs to the SusD family.

28188:CGC47 RS07845
gene id: 28188:CGC47_RS07845
uniprot id: A0A0B7HMS9
names: Similarity
messages: Belongs to the GARS family.

28188:CGC47 RS01980
gene id: 28188:CGC47_RS01980
uniprot id: A0A0B7IC76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

28188:CGC47 RS06355
gene id: 28188:CGC47_RS06355
uniprot id: A0A0B7IHB4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

28188:CGC47 RS07405
gene id: 28188:CGC47_RS07405
uniprot id: A0A0B7HM71
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

28188:CGC47 RS10655
gene id: 28188:CGC47_RS10655
uniprot id: A0A0B7I975
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

28188:CGC47 RS00440
gene id: 28188:CGC47_RS00440
uniprot id: A0A0B7GZP5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

28188:CGC47 RS07240
gene id: 28188:CGC47_RS07240
uniprot id: A0A0B7HKG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

28188:CGC47 RS03165
gene id: 28188:CGC47_RS03165
uniprot id: A0A0B7HAG6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

28188:CGC47 RS07425
gene id: 28188:CGC47_RS07425
uniprot id: A0A250EYZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

28188:CGC47 RS01685
gene id: 28188:CGC47_RS01685
uniprot id: A0A0B7H3T3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

28188:CGC47 RS02605
gene id: 28188:CGC47_RS02605
uniprot id: A0A0B7H2M9
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

28188:CGC47 RS00075
gene id: 28188:CGC47_RS00075
uniprot id: A0A0B7I4N0
names: Similarity
messages: Belongs to the NusB family.

28188:CGC47 RS08055
gene id: 28188:CGC47_RS08055
uniprot id: A0A0B7HDJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

28188:CGC47 RS06915
gene id: 28188:CGC47_RS06915
uniprot id: A0A0B7IE45
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

28188:CGC47 RS09855
gene id: 28188:CGC47_RS09855
uniprot id: A0A0B7HJE7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

28188:CGC47 RS04595
gene id: 28188:CGC47_RS04595
uniprot id: A0A0B7HNC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

28188:CGC47 RS04430
gene id: 28188:CGC47_RS04430
uniprot id: A0A0B7HLC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

28188:CGC47 RS09790
gene id: 28188:CGC47_RS09790
uniprot id: A0A0B7HME5
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS05705
gene id: 28188:CGC47_RS05705
uniprot id: A0A0B7I9E3
names: Similarity
messages: Belongs to the UPF0145 family.

28188:CGC47 RS04700
gene id: 28188:CGC47_RS04700
uniprot id: A0A0B7HN20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS02645
gene id: 28188:CGC47_RS02645
uniprot id: A0A250EYV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

28188:CGC47 RS05700
gene id: 28188:CGC47_RS05700
uniprot id: A0A0B7HC98
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

28188:CGC47 RS02855
gene id: 28188:CGC47_RS02855
uniprot id: A0A0B7H5D8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

28188:CGC47 RS04670
gene id: 28188:CGC47_RS04670
uniprot id: A0A0B7HN38
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Membrane

28188:CGC47 RS04470
gene id: 28188:CGC47_RS04470
uniprot id: A0A0B7HUX2
names: Similarity
messages: Belongs to the SusD family.

28188:CGC47 RS09155
gene id: 28188:CGC47_RS09155
uniprot id: A0A0B7HDD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

28188:CGC47 RS01315
gene id: 28188:CGC47_RS01315
uniprot id: A0A0B7I453
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

28188:CGC47 RS09110
gene id: 28188:CGC47_RS09110
uniprot id: A0A0B7IJY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

28188:CGC47 RS04850
gene id: 28188:CGC47_RS04850
uniprot id: A0A0B7HR21
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

28188:CGC47 RS06690
gene id: 28188:CGC47_RS06690
uniprot id: A0A0B7HPD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

28188:CGC47 RS01165
gene id: 28188:CGC47_RS01165
uniprot id: A0A0B7H0C2
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS08685
gene id: 28188:CGC47_RS08685
uniprot id: A0A0B7H4U4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28188:CGC47 RS05245
gene id: 28188:CGC47_RS05245
uniprot id: A0A0B7HBS2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

28188:CGC47 RS07495
gene id: 28188:CGC47_RS07495
uniprot id: A0A0B7I9C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

28188:CGC47 RS10160
gene id: 28188:CGC47_RS10160
uniprot id: A0A0B7H339
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

28188:CGC47 RS04345
gene id: 28188:CGC47_RS04345
uniprot id: A0A0B7HRE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

28188:CGC47 RS05430
gene id: 28188:CGC47_RS05430
uniprot id: A0A0B7HCW5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

28188:CGC47 RS07975
gene id: 28188:CGC47_RS07975
uniprot id: A0A0B7HJ50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

28188:CGC47 RS02710
gene id: 28188:CGC47_RS02710
uniprot id: A0A0B7H6H1
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

28188:CGC47 RS01525
gene id: 28188:CGC47_RS01525
uniprot id: A0A0B7H846
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

28188:CGC47 RS02590
gene id: 28188:CGC47_RS02590
uniprot id: A0A0B7HCP2
names: Similarity
messages: Belongs to the ribF family.

28188:CGC47 RS07835
gene id: 28188:CGC47_RS07835
uniprot id: A0A0B7HGG5
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS07055
gene id: 28188:CGC47_RS07055
uniprot id: A0A0B7HJB9
names: Similarity
messages: Belongs to the NAD synthetase family.

28188:CGC47 RS02860
gene id: 28188:CGC47_RS02860
uniprot id: A0A0B7GZV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

28188:CGC47 RS05310
gene id: 28188:CGC47_RS05310
uniprot id: A0A0B7H8M3
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

28188:CGC47 RS04070
gene id: 28188:CGC47_RS04070
uniprot id: A0A0B7IPB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

28188:CGC47 RS09805
gene id: 28188:CGC47_RS09805
uniprot id: A0A0B7HJB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

28188:CGC47 RS03310
gene id: 28188:CGC47_RS03310
uniprot id: A0A0B7HSK0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

28188:CGC47 RS01680
gene id: 28188:CGC47_RS01680
uniprot id: A0A250G737
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

28188:CGC47 RS05595
gene id: 28188:CGC47_RS05595
uniprot id: A0A0B7HIL9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

28188:CGC47 RS04970
gene id: 28188:CGC47_RS04970
uniprot id: A0A0B7HMJ0
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS07950
gene id: 28188:CGC47_RS07950
uniprot id: A0A0B7HJ94
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS09655
gene id: 28188:CGC47_RS09655
uniprot id: A0A0B7HIX6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS02815
gene id: 28188:CGC47_RS02815
uniprot id: A0A0B7H5F6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

28188:CGC47 RS06225
gene id: 28188:CGC47_RS06225
uniprot id: A0A0B7HUT9
names: Similarity
messages: Belongs to the transposase 27 family.

28188:CGC47 RS02340
gene id: 28188:CGC47_RS02340
uniprot id: A0A0B7IT83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

28188:CGC47 RS04840
gene id: 28188:CGC47_RS04840
uniprot id: A0A0B7HMU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

28188:CGC47 RS03440
gene id: 28188:CGC47_RS03440
uniprot id: A0A0B7I8C4
names: Similarity
messages: Belongs to the Fur family.

28188:CGC47 RS09215
gene id: 28188:CGC47_RS09215
uniprot id: A0A0B7IQF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

28188:CGC47 RS02390
gene id: 28188:CGC47_RS02390
uniprot id: A0A0B7I9I6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

28188:CGC47 RS01910
gene id: 28188:CGC47_RS01910
uniprot id: A0A0B7H614
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

28188:CGC47 RS08935
gene id: 28188:CGC47_RS08935
uniprot id: A0A0B7H2Q8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

28188:CGC47 RS04975
gene id: 28188:CGC47_RS04975
uniprot id: A0A0B7IJS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

28188:CGC47 RS02825
gene id: 28188:CGC47_RS02825
uniprot id: A0A0B7H4K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

28188:CGC47 RS04985
gene id: 28188:CGC47_RS04985
uniprot id: A0A0B7HQQ4
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS08255
gene id: 28188:CGC47_RS08255
uniprot id: A0A0B7HJC1
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

28188:CGC47 RS07680
gene id: 28188:CGC47_RS07680
uniprot id: A0A0B7HI32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

28188:CGC47 RS07980
gene id: 28188:CGC47_RS07980
uniprot id: A0A0B7HHE6
names: Similarity
messages: Belongs to the peptidase M24B family.

28188:CGC47 RS09115
gene id: 28188:CGC47_RS09115
uniprot id: A0A0B7HFE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

28188:CGC47 RS06175
gene id: 28188:CGC47_RS06175
uniprot id: A0A0B7IBT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS03650
gene id: 28188:CGC47_RS03650
uniprot id: A0A0B7ID81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

28188:CGC47 RS02365
gene id: 28188:CGC47_RS02365
uniprot id: A0A0B7H4H4
names: Similarity
messages: Belongs to the DEAD box helicase family.

28188:CGC47 RS09985
gene id: 28188:CGC47_RS09985
uniprot id: A0A0B7HCA7
names: Similarity
messages: Belongs to the BshC family.

28188:CGC47 RS09515
gene id: 28188:CGC47_RS09515
uniprot id: A0A0B7H0A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

28188:CGC47 RS05845
gene id: 28188:CGC47_RS05845
uniprot id: A0A0B7HU14
names: Similarity
messages: Belongs to the DapA family.

28188:CGC47 RS08750
gene id: 28188:CGC47_RS08750
uniprot id: A0A0B7HA06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

28188:CGC47 RS09910
gene id: 28188:CGC47_RS09910
uniprot id: A0A0B7IF10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

28188:CGC47 RS05115
gene id: 28188:CGC47_RS05115
uniprot id: A0A0B7H214
names: Similarity
messages: Belongs to the RecJ family.

28188:CGC47 RS00785
gene id: 28188:CGC47_RS00785
uniprot id: A0A0B7INI2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

28188:CGC47 RS10315
gene id: 28188:CGC47_RS10315
uniprot id: A0A250F1R5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28188:CGC47 RS05610
gene id: 28188:CGC47_RS05610
uniprot id: A0A0B7I031
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

28188:CGC47 RS10415
gene id: 28188:CGC47_RS10415
uniprot id: A0A0B7HIG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

28188:CGC47 RS10345
gene id: 28188:CGC47_RS10345
uniprot id: A0A0B7HF87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

28188:CGC47 RS05815
gene id: 28188:CGC47_RS05815
uniprot id: A0A250EW59
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

28188:CGC47 RS06335
gene id: 28188:CGC47_RS06335
uniprot id: A0A0B7HPU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

28188:CGC47 RS10340
gene id: 28188:CGC47_RS10340
uniprot id: A0A0B7HLI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Cytoplasm

28188:CGC47 RS06600
gene id: 28188:CGC47_RS06600
uniprot id: A0A0B7HJI4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

28188:CGC47 RS07825
gene id: 28188:CGC47_RS07825
uniprot id: A0A0B7HMU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

28188:CGC47 RS09830
gene id: 28188:CGC47_RS09830
uniprot id: A0A0B7HKN8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28188:CGC47 RS06735
gene id: 28188:CGC47_RS06735
uniprot id: A0A0B7HHV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

28188:CGC47 RS01445
gene id: 28188:CGC47_RS01445
uniprot id: A0A0B7H461
names: Similarity
messages: Belongs to the Gram-positive plasmids replication protein type 1 family.

28188:CGC47 RS06760
gene id: 28188:CGC47_RS06760
uniprot id: A0A0B7I9C8
names: Similarity
messages: Belongs to the SufE family.

28188:CGC47 RS06190
gene id: 28188:CGC47_RS06190
uniprot id: A0A0B7IRA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

28188:CGC47 RS09705
gene id: 28188:CGC47_RS09705
uniprot id: A0A0B7HM70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

28188:CGC47 RS10355
gene id: 28188:CGC47_RS10355
uniprot id: A0A0B7I665
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

28188:CGC47 RS02455
gene id: 28188:CGC47_RS02455
uniprot id: A0A0B7ICB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

28188:CGC47 RS08365
gene id: 28188:CGC47_RS08365
uniprot id: A0A0B7HDJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

28188:CGC47 RS09935
gene id: 28188:CGC47_RS09935
uniprot id: A0A0B7IS76
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

28188:CGC47 RS09295
gene id: 28188:CGC47_RS09295
uniprot id: A0A0B7HDQ2
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

28188:CGC47 RS06015
gene id: 28188:CGC47_RS06015
uniprot id: A0A250G3G1
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS00195
gene id: 28188:CGC47_RS00195
uniprot id: A0A0B7H775
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

28188:CGC47 RS01915
gene id: 28188:CGC47_RS01915
uniprot id: A0A0B7IAJ7
names: Subcellular Location Annotation
messages: Membrane

28188:CGC47 RS05020
gene id: 28188:CGC47_RS05020
uniprot id: A0A0B7HQP1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS05100
gene id: 28188:CGC47_RS05100
uniprot id: A0A0B7H4Z1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS07735
gene id: 28188:CGC47_RS07735
uniprot id: A0A0B7HLX7
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS05320
gene id: 28188:CGC47_RS05320
uniprot id: A0A0B7H6Y5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

28188:CGC47 RS07580
gene id: 28188:CGC47_RS07580
uniprot id: A0A0B7H921
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

28188:CGC47 RS02470
gene id: 28188:CGC47_RS02470
uniprot id: A0A0B7HCA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

28188:CGC47 RS01645
gene id: 28188:CGC47_RS01645
uniprot id: A0A0B7H822
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

28188:CGC47 RS08340
gene id: 28188:CGC47_RS08340
uniprot id: A0A0B7HIN2
names: Similarity
messages: Belongs to the SCO1/2 family.

28188:CGC47 RS09050
gene id: 28188:CGC47_RS09050
uniprot id: A0A0B7H5L7
names: Similarity
messages: Belongs to the heat shock protein 90 family.

28188:CGC47 RS08285
gene id: 28188:CGC47_RS08285
uniprot id: A0A0B7HIF3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

28188:CGC47 RS02070
gene id: 28188:CGC47_RS02070
uniprot id: A0A0B7H253
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS04085
gene id: 28188:CGC47_RS04085
uniprot id: A0A0B7HRZ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS01675
gene id: 28188:CGC47_RS01675
uniprot id: A0A0B7H391
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS08480
gene id: 28188:CGC47_RS08480
uniprot id: A0A0B7HGT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

28188:CGC47 RS01760
gene id: 28188:CGC47_RS01760
uniprot id: A0A0B7H652
names: Similarity
messages: Belongs to the LOG family.

28188:CGC47 RS00755
gene id: 28188:CGC47_RS00755
uniprot id: A0A0B7H9G6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28188:CGC47 RS03560
gene id: 28188:CGC47_RS03560
uniprot id: A0A0B7HQ23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

28188:CGC47 RS04445
gene id: 28188:CGC47_RS04445
uniprot id: A0A0B7HR59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

28188:CGC47 RS07745
gene id: 28188:CGC47_RS07745
uniprot id: A0A0B7HN12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

28188:CGC47 RS05755
gene id: 28188:CGC47_RS05755
uniprot id: A0A0B7IJL6
names: Similarity
messages: Belongs to the thioredoxin family.

28188:CGC47 RS00900
gene id: 28188:CGC47_RS00900
uniprot id: A0A250EYP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

28188:CGC47 RS02750
gene id: 28188:CGC47_RS02750
uniprot id: A0A0B7H8Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

28188:CGC47 RS03920
gene id: 28188:CGC47_RS03920
uniprot id: A0A250EYB9
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

28188:CGC47 RS00095
gene id: 28188:CGC47_RS00095
uniprot id: A0A0B7HCT5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28188:CGC47 RS09695
gene id: 28188:CGC47_RS09695
uniprot id: A0A0B7HP85
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.