28109:PNIG RS17385
gene id: 28109:PNIG_RS17385
uniprot id: A0A379I339
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

28109:PNIG RS19310
gene id: 28109:PNIG_RS19310
uniprot id: A0A379I4C3
names: Similarity
messages: Belongs to the GbsR family.

28109:PNIG RS04865
gene id: 28109:PNIG_RS04865
uniprot id: A0A379HCI8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

28109:PNIG RS01880
gene id: 28109:PNIG_RS01880
uniprot id: A0A379HEH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

28109:PNIG RS04320
gene id: 28109:PNIG_RS04320
uniprot id: A0A379HD09
names: Similarity
messages: Belongs to the type III secretion exporter family.

28109:PNIG RS00590
gene id: 28109:PNIG_RS00590
uniprot id: A0A379H6H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

28109:PNIG RS09100
gene id: 28109:PNIG_RS09100
uniprot id: A0A379HA91
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

28109:PNIG RS13565
gene id: 28109:PNIG_RS13565
uniprot id: A0A379H7W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

28109:PNIG RS04290
gene id: 28109:PNIG_RS04290
uniprot id: A0A379HEL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

28109:PNIG RS10405
gene id: 28109:PNIG_RS10405
uniprot id: A0A379H9R0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

28109:PNIG RS09355
gene id: 28109:PNIG_RS09355
uniprot id: A0A379HA49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

28109:PNIG RS04870
gene id: 28109:PNIG_RS04870
uniprot id: A0A379HCK7
names: Similarity
messages: Belongs to the P(II) protein family.

28109:PNIG RS18130
gene id: 28109:PNIG_RS18130
uniprot id: A0A379I3W7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

28109:PNIG RS01435
gene id: 28109:PNIG_RS01435
uniprot id: A0A379HEH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

28109:PNIG RS02905
gene id: 28109:PNIG_RS02905
uniprot id: A0A379HE15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

28109:PNIG RS00135
gene id: 28109:PNIG_RS00135
uniprot id: A0A379H6C6
names: Similarity
messages: Belongs to the Smg family.

28109:PNIG RS14700
gene id: 28109:PNIG_RS14700
uniprot id: A0A379H7H5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

28109:PNIG RS12220
gene id: 28109:PNIG_RS12220
uniprot id: A0A379H8Q3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

28109:PNIG RS11525
gene id: 28109:PNIG_RS11525
uniprot id: A0A379H8Y0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS04985
gene id: 28109:PNIG_RS04985
uniprot id: A0A379HCJ2
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

28109:PNIG RS02620
gene id: 28109:PNIG_RS02620
uniprot id: A0A379HDX8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

28109:PNIG RS09300
gene id: 28109:PNIG_RS09300
uniprot id: A0A379HA52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

28109:PNIG RS15190
gene id: 28109:PNIG_RS15190
uniprot id: A0A379H6U3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

28109:PNIG RS02095
gene id: 28109:PNIG_RS02095
uniprot id: A0A379HE30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

28109:PNIG RS12680
gene id: 28109:PNIG_RS12680
uniprot id: A0A379H8B9
names: Similarity
messages: Belongs to the BolA/IbaG family.

28109:PNIG RS07370
gene id: 28109:PNIG_RS07370
uniprot id: A0A379HBB5
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

28109:PNIG RS01685
gene id: 28109:PNIG_RS01685
uniprot id: A0A379HEB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

28109:PNIG RS14090
gene id: 28109:PNIG_RS14090
uniprot id: A0A379H977
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

28109:PNIG RS00350
gene id: 28109:PNIG_RS00350
uniprot id: A0A379H684
names: PTM
messages: Binds 1 heme group per subunit.

28109:PNIG RS15060
gene id: 28109:PNIG_RS15060
uniprot id: A0A379H6Z1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Homodimer.

28109:PNIG RS06235
gene id: 28109:PNIG_RS06235
uniprot id: A0A379HDH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmI family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.

28109:PNIG RS11850
gene id: 28109:PNIG_RS11850
uniprot id: A0A379HAD3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

28109:PNIG RS00105
gene id: 28109:PNIG_RS00105
uniprot id: A0A379H681
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

28109:PNIG RS08300
gene id: 28109:PNIG_RS08300
uniprot id: A0A379HAM1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

28109:PNIG RS11275
gene id: 28109:PNIG_RS11275
uniprot id: A0A379H9H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS07940
gene id: 28109:PNIG_RS07940
uniprot id: A0A379HB54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

28109:PNIG RS03255
gene id: 28109:PNIG_RS03255
uniprot id: A0A379HDT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

28109:PNIG RS14080
gene id: 28109:PNIG_RS14080
uniprot id: A0A379H7M0
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS15505
gene id: 28109:PNIG_RS15505
uniprot id: A0A379HEV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

28109:PNIG RS12180
gene id: 28109:PNIG_RS12180
uniprot id: A0A379H8K4
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS15500
gene id: 28109:PNIG_RS15500
uniprot id: A0A379HEK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

28109:PNIG RS05350
gene id: 28109:PNIG_RS05350
uniprot id: A0A379HC97
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

28109:PNIG RS06195
gene id: 28109:PNIG_RS06195
uniprot id: A0A379HC48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

28109:PNIG RS12010
gene id: 28109:PNIG_RS12010
uniprot id: A0A379H8Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

28109:PNIG RS04100
gene id: 28109:PNIG_RS04100
uniprot id: A0A379HD83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

28109:PNIG RS12655
gene id: 28109:PNIG_RS12655
uniprot id: A0A379H9Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

28109:PNIG RS04900
gene id: 28109:PNIG_RS04900
uniprot id: A0A379HE86
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

28109:PNIG RS14230
gene id: 28109:PNIG_RS14230
uniprot id: A0A379H7J6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

28109:PNIG RS14930
gene id: 28109:PNIG_RS14930
uniprot id: A0A379H6Z5
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

28109:PNIG RS06960
gene id: 28109:PNIG_RS06960
uniprot id: A0A379HBM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

28109:PNIG RS04665
gene id: 28109:PNIG_RS04665
uniprot id: A0A379HCP2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

28109:PNIG RS17395
gene id: 28109:PNIG_RS17395
uniprot id: A0A379I3A2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

28109:PNIG RS11060
gene id: 28109:PNIG_RS11060
uniprot id: A0A379H957
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

28109:PNIG RS03790
gene id: 28109:PNIG_RS03790
uniprot id: A0A379HD70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

28109:PNIG RS13130
gene id: 28109:PNIG_RS13130
uniprot id: A0A379H872
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

28109:PNIG RS11805
gene id: 28109:PNIG_RS11805
uniprot id: A0A379H965
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

28109:PNIG RS17740
gene id: 28109:PNIG_RS17740
uniprot id: A0A379I3H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CsgA/CsgB family.
messages: Fimbrium

28109:PNIG RS04380
gene id: 28109:PNIG_RS04380
uniprot id: A0A379HD32
names: Similarity
messages: Belongs to the MlaA family.

28109:PNIG RS08120
gene id: 28109:PNIG_RS08120
uniprot id: A0A379HB41
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

28109:PNIG RS07970
gene id: 28109:PNIG_RS07970
uniprot id: A0A379HAV9
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

28109:PNIG RS00880
gene id: 28109:PNIG_RS00880
uniprot id: A0A379H6I7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

28109:PNIG RS19225
gene id: 28109:PNIG_RS19225
uniprot id: A0A379I461
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

28109:PNIG RS01160
gene id: 28109:PNIG_RS01160
uniprot id: A0A379H6W2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

28109:PNIG RS12905
gene id: 28109:PNIG_RS12905
uniprot id: A0A379H9T8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

28109:PNIG RS10440
gene id: 28109:PNIG_RS10440
uniprot id: A0A379H9G4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

28109:PNIG RS10375
gene id: 28109:PNIG_RS10375
uniprot id: A0A379H9Y2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

28109:PNIG RS05185
gene id: 28109:PNIG_RS05185
uniprot id: A0A379HCM1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

28109:PNIG RS18185
gene id: 28109:PNIG_RS18185
uniprot id: A0A379I3L8
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

28109:PNIG RS07745
gene id: 28109:PNIG_RS07745
uniprot id: A0A379HAZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

28109:PNIG RS06905
gene id: 28109:PNIG_RS06905
uniprot id: A0A379HBG2
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

28109:PNIG RS08035
gene id: 28109:PNIG_RS08035
uniprot id: A0A379HBA9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

28109:PNIG RS13860
gene id: 28109:PNIG_RS13860
uniprot id: A0A379H7S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

28109:PNIG RS01280
gene id: 28109:PNIG_RS01280
uniprot id: A0A379H6Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

28109:PNIG RS03375
gene id: 28109:PNIG_RS03375
uniprot id: A0A379HDP7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

28109:PNIG RS11680
gene id: 28109:PNIG_RS11680
uniprot id: A0A379H920
names: Similarity
messages: Belongs to the Skp family.

28109:PNIG RS11740
gene id: 28109:PNIG_RS11740
uniprot id: A0A379H8U0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

28109:PNIG RS12650
gene id: 28109:PNIG_RS12650
uniprot id: A0A379H8C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

28109:PNIG RS04275
gene id: 28109:PNIG_RS04275
uniprot id: A0A379HD52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

28109:PNIG RS10900
gene id: 28109:PNIG_RS10900
uniprot id: A0A379H9A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

28109:PNIG RS11865
gene id: 28109:PNIG_RS11865
uniprot id: A0A379H8Y7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

28109:PNIG RS14390
gene id: 28109:PNIG_RS14390
uniprot id: A0A379H911
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

28109:PNIG RS13015
gene id: 28109:PNIG_RS13015
uniprot id: A0A379H8B4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

28109:PNIG RS08330
gene id: 28109:PNIG_RS08330
uniprot id: A0A379HAQ7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

28109:PNIG RS01390
gene id: 28109:PNIG_RS01390
uniprot id: A0A379HEI7
names: Similarity
messages: Belongs to the CutA family.

28109:PNIG RS13835
gene id: 28109:PNIG_RS13835
uniprot id: A0A379H7V1
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

28109:PNIG RS01445
gene id: 28109:PNIG_RS01445
uniprot id: A0A379HEJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

28109:PNIG RS16485
gene id: 28109:PNIG_RS16485
uniprot id: A0A379HF71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

28109:PNIG RS12730
gene id: 28109:PNIG_RS12730
uniprot id: A0A379H8B2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

28109:PNIG RS02955
gene id: 28109:PNIG_RS02955
uniprot id: A0A379HDX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

28109:PNIG RS08170
gene id: 28109:PNIG_RS08170
uniprot id: A0A379HB30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

28109:PNIG RS00030
gene id: 28109:PNIG_RS00030
uniprot id: A0A379H5Z1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

28109:PNIG RS15070
gene id: 28109:PNIG_RS15070
uniprot id: A0A379H753
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

28109:PNIG RS04600
gene id: 28109:PNIG_RS04600
uniprot id: A0A379HEF3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

28109:PNIG RS14465
gene id: 28109:PNIG_RS14465
uniprot id: A0A379H7G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

28109:PNIG RS10470
gene id: 28109:PNIG_RS10470
uniprot id: A0A379H9H8
names: Similarity
messages: Belongs to the UPF0352 family.

28109:PNIG RS12950
gene id: 28109:PNIG_RS12950
uniprot id: A0A379H842
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS10390
gene id: 28109:PNIG_RS10390
uniprot id: A0A379H9H4
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

28109:PNIG RS06975
gene id: 28109:PNIG_RS06975
uniprot id: A0A379HBJ5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

28109:PNIG RS09475
gene id: 28109:PNIG_RS09475
uniprot id: A0A379HBP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

28109:PNIG RS09445
gene id: 28109:PNIG_RS09445
uniprot id: A0A379HA16
names: Similarity
messages: Belongs to the DsrF/TusC family.

28109:PNIG RS01865
gene id: 28109:PNIG_RS01865
uniprot id: A0A379HEB0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

28109:PNIG RS00770
gene id: 28109:PNIG_RS00770
uniprot id: A0A379H6N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

28109:PNIG RS02595
gene id: 28109:PNIG_RS02595
uniprot id: A0A379HE63
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

28109:PNIG RS14445
gene id: 28109:PNIG_RS14445
uniprot id: A0A379H7M4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

28109:PNIG RS03715
gene id: 28109:PNIG_RS03715
uniprot id: A0A379HDL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

28109:PNIG RS02445
gene id: 28109:PNIG_RS02445
uniprot id: A0A379HE54
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

28109:PNIG RS01830
gene id: 28109:PNIG_RS01830
uniprot id: A0A379HEI3
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

28109:PNIG RS17625
gene id: 28109:PNIG_RS17625
uniprot id: A0A379I3E3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

28109:PNIG RS14010
gene id: 28109:PNIG_RS14010
uniprot id: A0A379H7K0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

28109:PNIG RS14125
gene id: 28109:PNIG_RS14125
uniprot id: A0A379H7M5
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

28109:PNIG RS05340
gene id: 28109:PNIG_RS05340
uniprot id: A0A379HCG4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

28109:PNIG RS13180
gene id: 28109:PNIG_RS13180
uniprot id: A0A379H886
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

28109:PNIG RS01405
gene id: 28109:PNIG_RS01405
uniprot id: A0A379HEH1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

28109:PNIG RS12330
gene id: 28109:PNIG_RS12330
uniprot id: A0A379H8Q1
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

28109:PNIG RS14615
gene id: 28109:PNIG_RS14615
uniprot id: A0A379H7D7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

28109:PNIG RS14265
gene id: 28109:PNIG_RS14265
uniprot id: A0A379H7F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

28109:PNIG RS11905
gene id: 28109:PNIG_RS11905
uniprot id: A0A379H8S4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS15545
gene id: 28109:PNIG_RS15545
uniprot id: A0A379HEP1
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS10155
gene id: 28109:PNIG_RS10155
uniprot id: A0A379H9W0
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

28109:PNIG RS09805
gene id: 28109:PNIG_RS09805
uniprot id: A0A379H9U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

28109:PNIG RS10200
gene id: 28109:PNIG_RS10200
uniprot id: A0A379H9S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

28109:PNIG RS07520
gene id: 28109:PNIG_RS07520
uniprot id: A0A379HCS7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28109:PNIG RS19060
gene id: 28109:PNIG_RS19060
uniprot id: A0A379I477
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

28109:PNIG RS06490
gene id: 28109:PNIG_RS06490
uniprot id: A0A379HBT7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

28109:PNIG RS17140
gene id: 28109:PNIG_RS17140
uniprot id: A0A379I2Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

28109:PNIG RS00010
gene id: 28109:PNIG_RS00010
uniprot id: A0A379H660
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

28109:PNIG RS18470
gene id: 28109:PNIG_RS18470
uniprot id: A0A379I3T0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

28109:PNIG RS03880
gene id: 28109:PNIG_RS03880
uniprot id: A0A379HDA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

28109:PNIG RS14370
gene id: 28109:PNIG_RS14370
uniprot id: A0A379H7I7
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

28109:PNIG RS00385
gene id: 28109:PNIG_RS00385
uniprot id: A0A379H6D8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

28109:PNIG RS00430
gene id: 28109:PNIG_RS00430
uniprot id: A0A379H6F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

28109:PNIG RS15895
gene id: 28109:PNIG_RS15895
uniprot id: A0A379HF46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

28109:PNIG RS01860
gene id: 28109:PNIG_RS01860
uniprot id: A0A379HE88
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

28109:PNIG RS08335
gene id: 28109:PNIG_RS08335
uniprot id: A0A379HCD0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

28109:PNIG RS04075
gene id: 28109:PNIG_RS04075
uniprot id: A0A379HD93
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

28109:PNIG RS18140
gene id: 28109:PNIG_RS18140
uniprot id: A0A379I3M3
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS10150
gene id: 28109:PNIG_RS10150
uniprot id: A0A379H9T6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

28109:PNIG RS02975
gene id: 28109:PNIG_RS02975
uniprot id: A0A379HDY1
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS13880
gene id: 28109:PNIG_RS13880
uniprot id: A0A379H814
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

28109:PNIG RS12690
gene id: 28109:PNIG_RS12690
uniprot id: A0A379H8E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

28109:PNIG RS14790
gene id: 28109:PNIG_RS14790
uniprot id: A0A379H721
names: Similarity
messages: Belongs to the peptidase U62 family.

28109:PNIG RS12870
gene id: 28109:PNIG_RS12870
uniprot id: A0A379H849
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

28109:PNIG RS16500
gene id: 28109:PNIG_RS16500
uniprot id: A0A379HF76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

28109:PNIG RS09245
gene id: 28109:PNIG_RS09245
uniprot id: A0A379HAF1
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

28109:PNIG RS01700
gene id: 28109:PNIG_RS01700
uniprot id: A0A379HEF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

28109:PNIG RS10235
gene id: 28109:PNIG_RS10235
uniprot id: A0A379H9J6
names: Similarity
messages: Belongs to the citrate synthase family.

28109:PNIG RS00585
gene id: 28109:PNIG_RS00585
uniprot id: A0A379H6H9
names: Similarity
messages: Belongs to the thioredoxin family.

28109:PNIG RS00495
gene id: 28109:PNIG_RS00495
uniprot id: A0A379H6I6
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

28109:PNIG RS00580
gene id: 28109:PNIG_RS00580
uniprot id: A0A379H6A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

28109:PNIG RS16905
gene id: 28109:PNIG_RS16905
uniprot id: A0A379I4K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

28109:PNIG RS06315
gene id: 28109:PNIG_RS06315
uniprot id: A0A379HBT9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

28109:PNIG RS12170
gene id: 28109:PNIG_RS12170
uniprot id: A0A379H8S3
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

28109:PNIG RS16520
gene id: 28109:PNIG_RS16520
uniprot id: A0A379HFE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

28109:PNIG RS14025
gene id: 28109:PNIG_RS14025
uniprot id: A0A379H7P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

28109:PNIG RS18235
gene id: 28109:PNIG_RS18235
uniprot id: A0A379I3M9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

28109:PNIG RS09285
gene id: 28109:PNIG_RS09285
uniprot id: A0A379HA58
names: Similarity
messages: Belongs to the SufE family.

28109:PNIG RS00445
gene id: 28109:PNIG_RS00445
uniprot id: A0A379H6A2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

28109:PNIG RS06115
gene id: 28109:PNIG_RS06115
uniprot id: A0A379HC73
names: Subcellular Location Annotation
messages: Cytoplasm

28109:PNIG RS14785
gene id: 28109:PNIG_RS14785
uniprot id: A0A379H787
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

28109:PNIG RS18995
gene id: 28109:PNIG_RS18995
uniprot id: A0A379I4E2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28109:PNIG RS04235
gene id: 28109:PNIG_RS04235
uniprot id: A0A379HCZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

28109:PNIG RS02600
gene id: 28109:PNIG_RS02600
uniprot id: A0A379HE31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

28109:PNIG RS05365
gene id: 28109:PNIG_RS05365
uniprot id: A0A379HCN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

28109:PNIG RS05650
gene id: 28109:PNIG_RS05650
uniprot id: A0A379HC78
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

28109:PNIG RS15475
gene id: 28109:PNIG_RS15475
uniprot id: A0A379HEJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

28109:PNIG RS01285
gene id: 28109:PNIG_RS01285
uniprot id: A0A379H733
names: Similarity
messages: Belongs to the GSP N family.

28109:PNIG RS09690
gene id: 28109:PNIG_RS09690
uniprot id: A0A379HA53
names: Similarity
messages: Belongs to the fructosamine kinase family.

28109:PNIG RS03690
gene id: 28109:PNIG_RS03690
uniprot id: A0A379HDD6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

28109:PNIG RS06200
gene id: 28109:PNIG_RS06200
uniprot id: A0A379HBV8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS03240
gene id: 28109:PNIG_RS03240
uniprot id: A0A379HDH8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

28109:PNIG RS11310
gene id: 28109:PNIG_RS11310
uniprot id: A0A379H924
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

28109:PNIG RS09825
gene id: 28109:PNIG_RS09825
uniprot id: A0A379H9W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

28109:PNIG RS15970
gene id: 28109:PNIG_RS15970
uniprot id: A0A379HEV9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

28109:PNIG RS16860
gene id: 28109:PNIG_RS16860
uniprot id: A0A379I4Y7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

28109:PNIG RS13560
gene id: 28109:PNIG_RS13560
uniprot id: A0A379H7Y2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

28109:PNIG RS07525
gene id: 28109:PNIG_RS07525
uniprot id: A0A379HBL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

28109:PNIG RS03760
gene id: 28109:PNIG_RS03760
uniprot id: A0A379HDG2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

28109:PNIG RS01695
gene id: 28109:PNIG_RS01695
uniprot id: A0A379HEC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

28109:PNIG RS03235
gene id: 28109:PNIG_RS03235
uniprot id: A0A379HDH6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

28109:PNIG RS14365
gene id: 28109:PNIG_RS14365
uniprot id: A0A379H7C9
names: Similarity
messages: Belongs to the GSP E family.

28109:PNIG RS16090
gene id: 28109:PNIG_RS16090
uniprot id: A0A379HEX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS13175
gene id: 28109:PNIG_RS13175
uniprot id: A0A379H8F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

28109:PNIG RS17100
gene id: 28109:PNIG_RS17100
uniprot id: A0A379I347
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

28109:PNIG RS13740
gene id: 28109:PNIG_RS13740
uniprot id: A0A379H7M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

28109:PNIG RS12960
gene id: 28109:PNIG_RS12960
uniprot id: A0A379H8J3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

28109:PNIG RS14045
gene id: 28109:PNIG_RS14045
uniprot id: A0A379H7X6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS19290
gene id: 28109:PNIG_RS19290
uniprot id: A0A379I4C6
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

28109:PNIG RS17160
gene id: 28109:PNIG_RS17160
uniprot id: A0A379I3F1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

28109:PNIG RS11635
gene id: 28109:PNIG_RS11635
uniprot id: A0A379H923
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

28109:PNIG RS14375
gene id: 28109:PNIG_RS14375
uniprot id: A0A379H7G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

28109:PNIG RS01455
gene id: 28109:PNIG_RS01455
uniprot id: A0A379HEG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

28109:PNIG RS19340
gene id: 28109:PNIG_RS19340
uniprot id: A0A379I4D7
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

28109:PNIG RS04240
gene id: 28109:PNIG_RS04240
uniprot id: A0A379HEM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

28109:PNIG RS15485
gene id: 28109:PNIG_RS15485
uniprot id: A0A379HEX0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

28109:PNIG RS09585
gene id: 28109:PNIG_RS09585
uniprot id: A0A379HAD8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS07585
gene id: 28109:PNIG_RS07585
uniprot id: A0A379HB16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

28109:PNIG RS04590
gene id: 28109:PNIG_RS04590
uniprot id: A0A379HCT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28109:PNIG RS14205
gene id: 28109:PNIG_RS14205
uniprot id: A0A379H7D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

28109:PNIG RS09180
gene id: 28109:PNIG_RS09180
uniprot id: A0A379HA63
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

28109:PNIG RS11575
gene id: 28109:PNIG_RS11575
uniprot id: A0A379H940
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

28109:PNIG RS05825
gene id: 28109:PNIG_RS05825
uniprot id: A0A379HC52
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

28109:PNIG RS08400
gene id: 28109:PNIG_RS08400
uniprot id: A0A379HAJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

28109:PNIG RS17380
gene id: 28109:PNIG_RS17380
uniprot id: A0A379I3G6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

28109:PNIG RS10920
gene id: 28109:PNIG_RS10920
uniprot id: A0A379H9G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

28109:PNIG RS07985
gene id: 28109:PNIG_RS07985
uniprot id: A0A379HBC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

28109:PNIG RS13520
gene id: 28109:PNIG_RS13520
uniprot id: A0A379H7S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

28109:PNIG RS11875
gene id: 28109:PNIG_RS11875
uniprot id: A0A379H8R0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

28109:PNIG RS13575
gene id: 28109:PNIG_RS13575
uniprot id: A0A379H9G3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

28109:PNIG RS03030
gene id: 28109:PNIG_RS03030
uniprot id: A0A379HDK8
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

28109:PNIG RS09835
gene id: 28109:PNIG_RS09835
uniprot id: A0A379HBG8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

28109:PNIG RS01625
gene id: 28109:PNIG_RS01625
uniprot id: A0A379HEQ2
names: Subcellular Location Annotation
messages: Cytoplasm

28109:PNIG RS01410
gene id: 28109:PNIG_RS01410
uniprot id: A0A379HEJ7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

28109:PNIG RS10450
gene id: 28109:PNIG_RS10450
uniprot id: A0A379H9M6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

28109:PNIG RS05645
gene id: 28109:PNIG_RS05645
uniprot id: A0A379HC37
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

28109:PNIG RS10435
gene id: 28109:PNIG_RS10435
uniprot id: A0A379H9F7
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

28109:PNIG RS15940
gene id: 28109:PNIG_RS15940
uniprot id: A0A379HF28
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

28109:PNIG RS03900
gene id: 28109:PNIG_RS03900
uniprot id: A0A379HEW1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

28109:PNIG RS06935
gene id: 28109:PNIG_RS06935
uniprot id: A0A379HBX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

28109:PNIG RS03525
gene id: 28109:PNIG_RS03525
uniprot id: A0A379HDL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

28109:PNIG RS05215
gene id: 28109:PNIG_RS05215
uniprot id: A0A379HCK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

28109:PNIG RS00630
gene id: 28109:PNIG_RS00630
uniprot id: A0A379H6Q5
names: Similarity
messages: Belongs to the UPF0231 family.

28109:PNIG RS15800
gene id: 28109:PNIG_RS15800
uniprot id: A0A379HET8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

28109:PNIG RS04435
gene id: 28109:PNIG_RS04435
uniprot id: A0A379HCT3
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

28109:PNIG RS04760
gene id: 28109:PNIG_RS04760
uniprot id: A0A379HCV2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

28109:PNIG RS16470
gene id: 28109:PNIG_RS16470
uniprot id: A0A379HFC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

28109:PNIG RS00210
gene id: 28109:PNIG_RS00210
uniprot id: A0A379H6D6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS04255
gene id: 28109:PNIG_RS04255
uniprot id: A0A379HCW9
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

28109:PNIG RS11725
gene id: 28109:PNIG_RS11725
uniprot id: A0A379H8V3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

28109:PNIG RS08915
gene id: 28109:PNIG_RS08915
uniprot id: A0A379HC20
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

28109:PNIG RS18180
gene id: 28109:PNIG_RS18180
uniprot id: A0A379I3Y1
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

28109:PNIG RS14105
gene id: 28109:PNIG_RS14105
uniprot id: A0A379H7F4
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

28109:PNIG RS01270
gene id: 28109:PNIG_RS01270
uniprot id: A0A379H6S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

28109:PNIG RS00620
gene id: 28109:PNIG_RS00620
uniprot id: A0A379H696
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

28109:PNIG RS16190
gene id: 28109:PNIG_RS16190
uniprot id: A0A379HEZ9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

28109:PNIG RS14745
gene id: 28109:PNIG_RS14745
uniprot id: A0A379H8T6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

28109:PNIG RS12915
gene id: 28109:PNIG_RS12915
uniprot id: A0A379H8D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

28109:PNIG RS09625
gene id: 28109:PNIG_RS09625
uniprot id: A0A379HA00
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

28109:PNIG RS12740
gene id: 28109:PNIG_RS12740
uniprot id: A0A379H8D2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

28109:PNIG RS00785
gene id: 28109:PNIG_RS00785
uniprot id: A0A379H6D0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

28109:PNIG RS10225
gene id: 28109:PNIG_RS10225
uniprot id: A0A379HA14
names: Similarity
messages: Belongs to the PrpF family.

28109:PNIG RS11175
gene id: 28109:PNIG_RS11175
uniprot id: A0A379H9J4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

28109:PNIG RS11410
gene id: 28109:PNIG_RS11410
uniprot id: A0A379H9E4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

28109:PNIG RS16480
gene id: 28109:PNIG_RS16480
uniprot id: A0A379HGS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

28109:PNIG RS05255
gene id: 28109:PNIG_RS05255
uniprot id: A0A379HCE3
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS07995
gene id: 28109:PNIG_RS07995
uniprot id: A0A379HAT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

28109:PNIG RS07465
gene id: 28109:PNIG_RS07465
uniprot id: A0A379HB57
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

28109:PNIG RS09745
gene id: 28109:PNIG_RS09745
uniprot id: A0A379HAA5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28109:PNIG RS01645
gene id: 28109:PNIG_RS01645
uniprot id: A0A379HED8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

28109:PNIG RS04475
gene id: 28109:PNIG_RS04475
uniprot id: A0A379HCY8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28109:PNIG RS07960
gene id: 28109:PNIG_RS07960
uniprot id: A0A379HB26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

28109:PNIG RS12615
gene id: 28109:PNIG_RS12615
uniprot id: A0A379H8J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

28109:PNIG RS14135
gene id: 28109:PNIG_RS14135
uniprot id: A0A379H7F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

28109:PNIG RS14560
gene id: 28109:PNIG_RS14560
uniprot id: A0A379H788
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

28109:PNIG RS12540
gene id: 28109:PNIG_RS12540
uniprot id: A0A379H8I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

28109:PNIG RS15105
gene id: 28109:PNIG_RS15105
uniprot id: A0A379H6V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

28109:PNIG RS13205
gene id: 28109:PNIG_RS13205
uniprot id: A0A379H848
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

28109:PNIG RS00750
gene id: 28109:PNIG_RS00750
uniprot id: A0A379H844
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

28109:PNIG RS09750
gene id: 28109:PNIG_RS09750
uniprot id: A0A379HA44
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

28109:PNIG RS15495
gene id: 28109:PNIG_RS15495
uniprot id: A0A379HEN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

28109:PNIG RS01200
gene id: 28109:PNIG_RS01200
uniprot id: A0A379H6U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

28109:PNIG RS15215
gene id: 28109:PNIG_RS15215
uniprot id: A0A379H6T5
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

28109:PNIG RS09440
gene id: 28109:PNIG_RS09440
uniprot id: A0A379HA09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

28109:PNIG RS15090
gene id: 28109:PNIG_RS15090
uniprot id: A0A379H8L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

28109:PNIG RS09250
gene id: 28109:PNIG_RS09250
uniprot id: A0A379HA62
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

28109:PNIG RS09170
gene id: 28109:PNIG_RS09170
uniprot id: A0A379HAE2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

28109:PNIG RS00425
gene id: 28109:PNIG_RS00425
uniprot id: A0A379H678
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

28109:PNIG RS05250
gene id: 28109:PNIG_RS05250
uniprot id: A0A379HCB7
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS18810
gene id: 28109:PNIG_RS18810
uniprot id: A0A379I409
names: Similarity
messages: Belongs to the DEAD box helicase family.

28109:PNIG RS16230
gene id: 28109:PNIG_RS16230
uniprot id: A0A379HFA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

28109:PNIG RS13030
gene id: 28109:PNIG_RS13030
uniprot id: A0A379H858
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

28109:PNIG RS05035
gene id: 28109:PNIG_RS05035
uniprot id: A0A379HCI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

28109:PNIG RS13975
gene id: 28109:PNIG_RS13975
uniprot id: A0A379H7Q2
names: Similarity
messages: Belongs to the UPF0102 family.

28109:PNIG RS19555
gene id: 28109:PNIG_RS19555
uniprot id: A0A379I4G5
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

28109:PNIG RS09345
gene id: 28109:PNIG_RS09345
uniprot id: A0A379HAC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

28109:PNIG RS06085
gene id: 28109:PNIG_RS06085
uniprot id: A0A379HCD3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

28109:PNIG RS06390
gene id: 28109:PNIG_RS06390
uniprot id: A0A379HBV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

28109:PNIG RS13240
gene id: 28109:PNIG_RS13240
uniprot id: A0A379H7Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

28109:PNIG RS14695
gene id: 28109:PNIG_RS14695
uniprot id: A0A379H8U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

28109:PNIG RS11815
gene id: 28109:PNIG_RS11815
uniprot id: A0A379H8Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

28109:PNIG RS15975
gene id: 28109:PNIG_RS15975
uniprot id: A0A379HEU5
names: Similarity
messages: Belongs to the UPF0270 family.

28109:PNIG RS12940
gene id: 28109:PNIG_RS12940
uniprot id: A0A379H891
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

28109:PNIG RS00780
gene id: 28109:PNIG_RS00780
uniprot id: A0A379H6G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

28109:PNIG RS09215
gene id: 28109:PNIG_RS09215
uniprot id: A0A379HAL7
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

28109:PNIG RS01915
gene id: 28109:PNIG_RS01915
uniprot id: A0A379HFV6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

28109:PNIG RS12320
gene id: 28109:PNIG_RS12320
uniprot id: A0A379HA50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

28109:PNIG RS13670
gene id: 28109:PNIG_RS13670
uniprot id: A0A379H7P4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a complex with MdtJ.
messages: Membrane

28109:PNIG RS07890
gene id: 28109:PNIG_RS07890
uniprot id: A0A379HB64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

28109:PNIG RS09120
gene id: 28109:PNIG_RS09120
uniprot id: A0A379HAF4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

28109:PNIG RS04585
gene id: 28109:PNIG_RS04585
uniprot id: A0A379HCQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

28109:PNIG RS00115
gene id: 28109:PNIG_RS00115
uniprot id: A0A379H645
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

28109:PNIG RS01205
gene id: 28109:PNIG_RS01205
uniprot id: A0A379H6T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

28109:PNIG RS18630
gene id: 28109:PNIG_RS18630
uniprot id: A0A379I5N2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

28109:PNIG RS05440
gene id: 28109:PNIG_RS05440
uniprot id: A0A379HCE5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

28109:PNIG RS15515
gene id: 28109:PNIG_RS15515
uniprot id: A0A379HEL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

28109:PNIG RS13470
gene id: 28109:PNIG_RS13470
uniprot id: A0A379H9I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

28109:PNIG RS03890
gene id: 28109:PNIG_RS03890
uniprot id: A0A379HD54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

28109:PNIG RS04350
gene id: 28109:PNIG_RS04350
uniprot id: A0A379HD81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

28109:PNIG RS01375
gene id: 28109:PNIG_RS01375
uniprot id: A0A379HER8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

28109:PNIG RS11665
gene id: 28109:PNIG_RS11665
uniprot id: A0A379H8T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

28109:PNIG RS01000
gene id: 28109:PNIG_RS01000
uniprot id: A0A379H6P9
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

28109:PNIG RS09350
gene id: 28109:PNIG_RS09350
uniprot id: A0A379HA41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

28109:PNIG RS00015
gene id: 28109:PNIG_RS00015
uniprot id: A0A379H694
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

28109:PNIG RS03835
gene id: 28109:PNIG_RS03835
uniprot id: A0A379HDF9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

28109:PNIG RS04815
gene id: 28109:PNIG_RS04815
uniprot id: A0A379HCJ4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

28109:PNIG RS10855
gene id: 28109:PNIG_RS10855
uniprot id: A0A379H989
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

28109:PNIG RS12705
gene id: 28109:PNIG_RS12705
uniprot id: A0A379H9X3
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS02935
gene id: 28109:PNIG_RS02935
uniprot id: A0A379HDM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

28109:PNIG RS15490
gene id: 28109:PNIG_RS15490
uniprot id: A0A379HG79
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

28109:PNIG RS07065
gene id: 28109:PNIG_RS07065
uniprot id: A0A379HBP8
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS19370
gene id: 28109:PNIG_RS19370
uniprot id: A0A379I4P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

28109:PNIG RS14750
gene id: 28109:PNIG_RS14750
uniprot id: A0A379H7G2
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

28109:PNIG RS02660
gene id: 28109:PNIG_RS02660
uniprot id: A0A379HDS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

28109:PNIG RS06945
gene id: 28109:PNIG_RS06945
uniprot id: A0A379HBE5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

28109:PNIG RS11720
gene id: 28109:PNIG_RS11720
uniprot id: A0A379H8U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

28109:PNIG RS06140
gene id: 28109:PNIG_RS06140
uniprot id: A0A379HCC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PagL family.
messages: Cell outer membrane
messages: Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.
messages: Homodimer.

28109:PNIG RS13125
gene id: 28109:PNIG_RS13125
uniprot id: A0A379H819
names: Caution
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS02775
gene id: 28109:PNIG_RS02775
uniprot id: A0A379HFG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

28109:PNIG RS03975
gene id: 28109:PNIG_RS03975
uniprot id: A0A379HD41
names: Similarity
messages: Belongs to the UDPGP type 2 family.

28109:PNIG RS19210
gene id: 28109:PNIG_RS19210
uniprot id: A0A379I454
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

28109:PNIG RS00510
gene id: 28109:PNIG_RS00510
uniprot id: A0A379H679
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

28109:PNIG RS18405
gene id: 28109:PNIG_RS18405
uniprot id: A0A379I3V6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

28109:PNIG RS15085
gene id: 28109:PNIG_RS15085
uniprot id: A0A379H6W5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

28109:PNIG RS15460
gene id: 28109:PNIG_RS15460
uniprot id: A0A379HEK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

28109:PNIG RS14085
gene id: 28109:PNIG_RS14085
uniprot id: A0A379H7G3
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

28109:PNIG RS14775
gene id: 28109:PNIG_RS14775
uniprot id: A0A379H7A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

28109:PNIG RS19175
gene id: 28109:PNIG_RS19175
uniprot id: A0A379I4K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

28109:PNIG RS05910
gene id: 28109:PNIG_RS05910
uniprot id: A0A379HCG5
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS00160
gene id: 28109:PNIG_RS00160
uniprot id: A0A379H691
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS16065
gene id: 28109:PNIG_RS16065
uniprot id: A0A379HGI7
names: Similarity
messages: Belongs to the glutamate synthase family.

28109:PNIG RS03470
gene id: 28109:PNIG_RS03470
uniprot id: A0A379HDM5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

28109:PNIG RS01545
gene id: 28109:PNIG_RS01545
uniprot id: A0A379HEF8
names: Similarity
messages: Belongs to the transglycosylase Slt family.

28109:PNIG RS03905
gene id: 28109:PNIG_RS03905
uniprot id: A0A379HDI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

28109:PNIG RS02655
gene id: 28109:PNIG_RS02655
uniprot id: A0A379HDS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

28109:PNIG RS16495
gene id: 28109:PNIG_RS16495
uniprot id: A0A379HFF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

28109:PNIG RS15065
gene id: 28109:PNIG_RS15065
uniprot id: A0A379H6Y4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

28109:PNIG RS15780
gene id: 28109:PNIG_RS15780
uniprot id: A0A379HEQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

28109:PNIG RS14315
gene id: 28109:PNIG_RS14315
uniprot id: A0A379H7D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

28109:PNIG RS15755
gene id: 28109:PNIG_RS15755
uniprot id: A0A379HEQ4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

28109:PNIG RS04920
gene id: 28109:PNIG_RS04920
uniprot id: A0A379HCJ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

28109:PNIG RS08155
gene id: 28109:PNIG_RS08155
uniprot id: A0A379HAS2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

28109:PNIG RS08505
gene id: 28109:PNIG_RS08505
uniprot id: A0A379HAI8
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS01790
gene id: 28109:PNIG_RS01790
uniprot id: A0A379HE92
names: Similarity
messages: Belongs to the histone deacetylase family.

28109:PNIG RS09620
gene id: 28109:PNIG_RS09620
uniprot id: A0A379H9Z7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.

28109:PNIG RS04940
gene id: 28109:PNIG_RS04940
uniprot id: A0A379HCH6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

28109:PNIG RS14005
gene id: 28109:PNIG_RS14005
uniprot id: A0A379H7H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

28109:PNIG RS15985
gene id: 28109:PNIG_RS15985
uniprot id: A0A379HF38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

28109:PNIG RS13540
gene id: 28109:PNIG_RS13540
uniprot id: A0A379H7R7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

28109:PNIG RS01710
gene id: 28109:PNIG_RS01710
uniprot id: A0A379HEB2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

28109:PNIG RS05335
gene id: 28109:PNIG_RS05335
uniprot id: A0A379HCC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

28109:PNIG RS14360
gene id: 28109:PNIG_RS14360
uniprot id: A0A379H7D0
names: Similarity
messages: Belongs to the GSP E family.

28109:PNIG RS14110
gene id: 28109:PNIG_RS14110
uniprot id: A0A379H7I2
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

28109:PNIG RS09815
gene id: 28109:PNIG_RS09815
uniprot id: A0A379HA04
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS14565
gene id: 28109:PNIG_RS14565
uniprot id: A0A379H7E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

28109:PNIG RS09860
gene id: 28109:PNIG_RS09860
uniprot id: A0A379H9Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

28109:PNIG RS01210
gene id: 28109:PNIG_RS01210
uniprot id: A0A379H6X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

28109:PNIG RS11705
gene id: 28109:PNIG_RS11705
uniprot id: A0A379H982
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

28109:PNIG RS11710
gene id: 28109:PNIG_RS11710
uniprot id: A0A379H916
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

28109:PNIG RS13000
gene id: 28109:PNIG_RS13000
uniprot id: A0A379H834
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28109:PNIG RS18340
gene id: 28109:PNIG_RS18340
uniprot id: A0A379I3Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

28109:PNIG RS03895
gene id: 28109:PNIG_RS03895
uniprot id: A0A379HD75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

28109:PNIG RS13020
gene id: 28109:PNIG_RS13020
uniprot id: A0A379H811
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

28109:PNIG RS11235
gene id: 28109:PNIG_RS11235
uniprot id: A0A379H915
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

28109:PNIG RS09235
gene id: 28109:PNIG_RS09235
uniprot id: A0A379HA65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

28109:PNIG RS12560
gene id: 28109:PNIG_RS12560
uniprot id: A0A379H8S0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

28109:PNIG RS03675
gene id: 28109:PNIG_RS03675
uniprot id: A0A379HD90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

28109:PNIG RS11695
gene id: 28109:PNIG_RS11695
uniprot id: A0A379H8V4
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

28109:PNIG RS10490
gene id: 28109:PNIG_RS10490
uniprot id: A0A379H9E8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28109:PNIG RS00545
gene id: 28109:PNIG_RS00545
uniprot id: A0A379H6J6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

28109:PNIG RS00055
gene id: 28109:PNIG_RS00055
uniprot id: A0A379H672
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

28109:PNIG RS15375
gene id: 28109:PNIG_RS15375
uniprot id: A0A379HEI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

28109:PNIG RS16475
gene id: 28109:PNIG_RS16475
uniprot id: A0A379HFF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

28109:PNIG RS03490
gene id: 28109:PNIG_RS03490
uniprot id: A0A379HDH0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

28109:PNIG RS12285
gene id: 28109:PNIG_RS12285
uniprot id: A0A379H8G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

28109:PNIG RS03150
gene id: 28109:PNIG_RS03150
uniprot id: A0A379HDN7
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

28109:PNIG RS04470
gene id: 28109:PNIG_RS04470
uniprot id: A0A379HCT5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS01120
gene id: 28109:PNIG_RS01120
uniprot id: A0A379H6L3
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS09630
gene id: 28109:PNIG_RS09630
uniprot id: A0A379HBL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

28109:PNIG RS00765
gene id: 28109:PNIG_RS00765
uniprot id: A0A379H6J7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

28109:PNIG RS11080
gene id: 28109:PNIG_RS11080
uniprot id: A0A379H936
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

28109:PNIG RS12295
gene id: 28109:PNIG_RS12295
uniprot id: A0A379H8K0
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

28109:PNIG RS08210
gene id: 28109:PNIG_RS08210
uniprot id: A0A379HAS1
names: Similarity
messages: Belongs to the DEAD box helicase family.

28109:PNIG RS14515
gene id: 28109:PNIG_RS14515
uniprot id: A0A379H7F7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

28109:PNIG RS04070
gene id: 28109:PNIG_RS04070
uniprot id: A0A379HD57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

28109:PNIG RS10915
gene id: 28109:PNIG_RS10915
uniprot id: A0A379H9N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

28109:PNIG RS09030
gene id: 28109:PNIG_RS09030
uniprot id: A0A379HAA0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

28109:PNIG RS04355
gene id: 28109:PNIG_RS04355
uniprot id: A0A379HD34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

28109:PNIG RS02950
gene id: 28109:PNIG_RS02950
uniprot id: A0A379HE11
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS04225
gene id: 28109:PNIG_RS04225
uniprot id: A0A379HD63
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

28109:PNIG RS14505
gene id: 28109:PNIG_RS14505
uniprot id: A0A379H7A2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

28109:PNIG RS02980
gene id: 28109:PNIG_RS02980
uniprot id: A0A379HDL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

28109:PNIG RS09520
gene id: 28109:PNIG_RS09520
uniprot id: A0A379HA18
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

28109:PNIG RS02100
gene id: 28109:PNIG_RS02100
uniprot id: A0A379HE50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

28109:PNIG RS02925
gene id: 28109:PNIG_RS02925
uniprot id: A0A379HDQ7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

28109:PNIG RS16545
gene id: 28109:PNIG_RS16545
uniprot id: A0A379HFG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

28109:PNIG RS06170
gene id: 28109:PNIG_RS06170
uniprot id: A0A379HC62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

28109:PNIG RS13305
gene id: 28109:PNIG_RS13305
uniprot id: A0A379H826
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

28109:PNIG RS19750
gene id: 28109:PNIG_RS19750
uniprot id: A0A379I4T9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Binds 1 sodium ion per monomer.
messages: Binds 2 magnesium ions per monomer.
messages: Homotetramer.

28109:PNIG RS03495
gene id: 28109:PNIG_RS03495
uniprot id: A0A379HDN3
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS00025
gene id: 28109:PNIG_RS00025
uniprot id: A0A379H628
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

28109:PNIG RS10425
gene id: 28109:PNIG_RS10425
uniprot id: A0A379H9X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

28109:PNIG RS15365
gene id: 28109:PNIG_RS15365
uniprot id: A0A379HG59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28109:PNIG RS04790
gene id: 28109:PNIG_RS04790
uniprot id: A0A379HCK8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

28109:PNIG RS16030
gene id: 28109:PNIG_RS16030
uniprot id: A0A379HF63
names: Similarity
messages: Belongs to the UPF0319 family.

28109:PNIG RS12545
gene id: 28109:PNIG_RS12545
uniprot id: A0A379H8D1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28109:PNIG RS18350
gene id: 28109:PNIG_RS18350
uniprot id: A0A379I3U7
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS14710
gene id: 28109:PNIG_RS14710
uniprot id: A0A379H729
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

28109:PNIG RS04935
gene id: 28109:PNIG_RS04935
uniprot id: A0A379HCS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

28109:PNIG RS17415
gene id: 28109:PNIG_RS17415
uniprot id: A0A379I4Z4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

28109:PNIG RS05370
gene id: 28109:PNIG_RS05370
uniprot id: A0A379HCH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

28109:PNIG RS13950
gene id: 28109:PNIG_RS13950
uniprot id: A0A379H7I5
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS05830
gene id: 28109:PNIG_RS05830
uniprot id: A0A379HC94
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

28109:PNIG RS13040
gene id: 28109:PNIG_RS13040
uniprot id: A0A379H868
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

28109:PNIG RS00050
gene id: 28109:PNIG_RS00050
uniprot id: A0A379H680
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

28109:PNIG RS10410
gene id: 28109:PNIG_RS10410
uniprot id: A0A379H9J5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

28109:PNIG RS17750
gene id: 28109:PNIG_RS17750
uniprot id: A0A379I3R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

28109:PNIG RS05605
gene id: 28109:PNIG_RS05605
uniprot id: A0A379HC88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

28109:PNIG RS03485
gene id: 28109:PNIG_RS03485
uniprot id: A0A379HDD9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

28109:PNIG RS19250
gene id: 28109:PNIG_RS19250
uniprot id: A0A379I4B8
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

28109:PNIG RS01440
gene id: 28109:PNIG_RS01440
uniprot id: A0A379HEH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

28109:PNIG RS06300
gene id: 28109:PNIG_RS06300
uniprot id: A0A379HC95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

28109:PNIG RS13235
gene id: 28109:PNIG_RS13235
uniprot id: A0A379H7W9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

28109:PNIG RS16920
gene id: 28109:PNIG_RS16920
uniprot id: A0A379I6B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

28109:PNIG RS11930
gene id: 28109:PNIG_RS11930
uniprot id: A0A379HAC4
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS01815
gene id: 28109:PNIG_RS01815
uniprot id: A0A379HEC1
names: Similarity
messages: Belongs to the GARS family.

28109:PNIG RS06980
gene id: 28109:PNIG_RS06980
uniprot id: A0A379HD30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

28109:PNIG RS11530
gene id: 28109:PNIG_RS11530
uniprot id: A0A379H8Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

28109:PNIG RS06430
gene id: 28109:PNIG_RS06430
uniprot id: A0A379HBY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

28109:PNIG RS19065
gene id: 28109:PNIG_RS19065
uniprot id: A0A379I434
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

28109:PNIG RS02415
gene id: 28109:PNIG_RS02415
uniprot id: A0A379HE79
names: Similarity
messages: Belongs to the RelE toxin family.

28109:PNIG RS13780
gene id: 28109:PNIG_RS13780
uniprot id: A0A379H836
names: Similarity
messages: Belongs to the glutathione peroxidase family.

28109:PNIG RS12595
gene id: 28109:PNIG_RS12595
uniprot id: A0A379H8C1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

28109:PNIG RS15920
gene id: 28109:PNIG_RS15920
uniprot id: A0A379HEW6
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS09065
gene id: 28109:PNIG_RS09065
uniprot id: A0A379HAQ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

28109:PNIG RS09515
gene id: 28109:PNIG_RS09515
uniprot id: A0A379HA17
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS04675
gene id: 28109:PNIG_RS04675
uniprot id: A0A379HCP4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

28109:PNIG RS07650
gene id: 28109:PNIG_RS07650
uniprot id: A0A379HB89
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

28109:PNIG RS13845
gene id: 28109:PNIG_RS13845
uniprot id: A0A379H7M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

28109:PNIG RS04420
gene id: 28109:PNIG_RS04420
uniprot id: A0A379HCU4
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

28109:PNIG RS13870
gene id: 28109:PNIG_RS13870
uniprot id: A0A379H7K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

28109:PNIG RS01850
gene id: 28109:PNIG_RS01850
uniprot id: A0A379HEC0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

28109:PNIG RS09265
gene id: 28109:PNIG_RS09265
uniprot id: A0A379HAK7
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

28109:PNIG RS03785
gene id: 28109:PNIG_RS03785
uniprot id: A0A379HDH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

28109:PNIG RS08165
gene id: 28109:PNIG_RS08165
uniprot id: A0A379HAY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

28109:PNIG RS10415
gene id: 28109:PNIG_RS10415
uniprot id: A0A379H9I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

28109:PNIG RS13910
gene id: 28109:PNIG_RS13910
uniprot id: A0A379H7R1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

28109:PNIG RS16215
gene id: 28109:PNIG_RS16215
uniprot id: A0A379HGM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

28109:PNIG RS00715
gene id: 28109:PNIG_RS00715
uniprot id: A0A379H6J2
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS05460
gene id: 28109:PNIG_RS05460
uniprot id: A0A379HDW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

28109:PNIG RS17790
gene id: 28109:PNIG_RS17790
uniprot id: A0A379I3I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

28109:PNIG RS12610
gene id: 28109:PNIG_RS12610
uniprot id: A0A379H8R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

28109:PNIG RS16490
gene id: 28109:PNIG_RS16490
uniprot id: A0A379HF45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

28109:PNIG RS13220
gene id: 28109:PNIG_RS13220
uniprot id: A0A379H9N0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

28109:PNIG RS11675
gene id: 28109:PNIG_RS11675
uniprot id: A0A379H8W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

28109:PNIG RS13665
gene id: 28109:PNIG_RS13665
uniprot id: A0A379H7U7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a complex with MdtI.
messages: Membrane

28109:PNIG RS09590
gene id: 28109:PNIG_RS09590
uniprot id: A0A379HA76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

28109:PNIG RS15950
gene id: 28109:PNIG_RS15950
uniprot id: A0A379HGG8
names: Similarity
messages: Belongs to the SlyX family.

28109:PNIG RS09305
gene id: 28109:PNIG_RS09305
uniprot id: A0A379HA61
names: Similarity
messages: Belongs to the UPF0434 family.

28109:PNIG RS04345
gene id: 28109:PNIG_RS04345
uniprot id: A0A379HEK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

28109:PNIG RS13300
gene id: 28109:PNIG_RS13300
uniprot id: A0A379H843
names: Similarity
messages: Belongs to the peptidase M17 family.

28109:PNIG RS05465
gene id: 28109:PNIG_RS05465
uniprot id: A0A379HCL9
names: Similarity
messages: Belongs to the PhoH family.

28109:PNIG RS03410
gene id: 28109:PNIG_RS03410
uniprot id: A0A379HF47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

28109:PNIG RS13075
gene id: 28109:PNIG_RS13075
uniprot id: A0A379H825
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

28109:PNIG RS09655
gene id: 28109:PNIG_RS09655
uniprot id: A0A379H9X4
names: Subcellular Location Annotation
messages: Cytoplasm

28109:PNIG RS00745
gene id: 28109:PNIG_RS00745
uniprot id: A0A379H6S8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

28109:PNIG RS00775
gene id: 28109:PNIG_RS00775
uniprot id: A0A379H6G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

28109:PNIG RS16025
gene id: 28109:PNIG_RS16025
uniprot id: A0A379HEV4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

28109:PNIG RS16555
gene id: 28109:PNIG_RS16555
uniprot id: A0A379HF70
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

28109:PNIG RS09850
gene id: 28109:PNIG_RS09850
uniprot id: A0A379H9T0
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

28109:PNIG RS15905
gene id: 28109:PNIG_RS15905
uniprot id: A0A379HEV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

28109:PNIG RS18035
gene id: 28109:PNIG_RS18035
uniprot id: A0A379I3I5
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

28109:PNIG RS04090
gene id: 28109:PNIG_RS04090
uniprot id: A0A379HEQ8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

28109:PNIG RS04220
gene id: 28109:PNIG_RS04220
uniprot id: A0A379HD29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

28109:PNIG RS16790
gene id: 28109:PNIG_RS16790
uniprot id: A0A379I4I8
names: Similarity
messages: Belongs to the UPF0178 family.

28109:PNIG RS14510
gene id: 28109:PNIG_RS14510
uniprot id: A0A379H7A0
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

28109:PNIG RS01155
gene id: 28109:PNIG_RS01155
uniprot id: A0A379H6S9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS14765
gene id: 28109:PNIG_RS14765
uniprot id: A0A379H755
names: Similarity
messages: Belongs to the HesB/IscA family.

28109:PNIG RS11395
gene id: 28109:PNIG_RS11395
uniprot id: A0A379H914
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

28109:PNIG RS03090
gene id: 28109:PNIG_RS03090
uniprot id: A0A379HDK4
names: Similarity
messages: Belongs to the peptidase M24B family.

28109:PNIG RS05850
gene id: 28109:PNIG_RS05850
uniprot id: A0A379HDQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

28109:PNIG RS12365
gene id: 28109:PNIG_RS12365
uniprot id: A0A379H8H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

28109:PNIG RS03845
gene id: 28109:PNIG_RS03845
uniprot id: A0A379HD85
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

28109:PNIG RS04095
gene id: 28109:PNIG_RS04095
uniprot id: A0A379HDD1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

28109:PNIG RS18095
gene id: 28109:PNIG_RS18095
uniprot id: A0A379I3P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

28109:PNIG RS04045
gene id: 28109:PNIG_RS04045
uniprot id: A0A379HD17
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

28109:PNIG RS17730
gene id: 28109:PNIG_RS17730
uniprot id: A0A379I3C1
names: Function
messages: May be involved in the biogenesis of curli organelles.

28109:PNIG RS13475
gene id: 28109:PNIG_RS13475
uniprot id: A0A379H889
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

28109:PNIG RS13045
gene id: 28109:PNIG_RS13045
uniprot id: A0A379H839
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

28109:PNIG RS00760
gene id: 28109:PNIG_RS00760
uniprot id: A0A379H6L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

28109:PNIG RS01885
gene id: 28109:PNIG_RS01885
uniprot id: A0A379HE75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

28109:PNIG RS08135
gene id: 28109:PNIG_RS08135
uniprot id: A0A379HCH1
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

28109:PNIG RS16550
gene id: 28109:PNIG_RS16550
uniprot id: A0A379HF85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

28109:PNIG RS03730
gene id: 28109:PNIG_RS03730
uniprot id: A0A379HD86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

28109:PNIG RS19260
gene id: 28109:PNIG_RS19260
uniprot id: A0A379I463
names: Similarity
messages: Belongs to the alkaline phosphatase family.

28109:PNIG RS08080
gene id: 28109:PNIG_RS08080
uniprot id: A0A379HCI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

28109:PNIG RS05200
gene id: 28109:PNIG_RS05200
uniprot id: A0A379HCF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

28109:PNIG RS12980
gene id: 28109:PNIG_RS12980
uniprot id: A0A379H862
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

28109:PNIG RS13650
gene id: 28109:PNIG_RS13650
uniprot id: A0A379H7R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

28109:PNIG RS03810
gene id: 28109:PNIG_RS03810
uniprot id: A0A379HDF3
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS15660
gene id: 28109:PNIG_RS15660
uniprot id: A0A379HEZ0
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

28109:PNIG RS15395
gene id: 28109:PNIG_RS15395
uniprot id: A0A379HEJ0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

28109:PNIG RS11110
gene id: 28109:PNIG_RS11110
uniprot id: A0A379H9B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

28109:PNIG RS13900
gene id: 28109:PNIG_RS13900
uniprot id: A0A379H7L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

28109:PNIG RS13570
gene id: 28109:PNIG_RS13570
uniprot id: A0A379H7R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

28109:PNIG RS04415
gene id: 28109:PNIG_RS04415
uniprot id: A0A379HCU9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

28109:PNIG RS04800
gene id: 28109:PNIG_RS04800
uniprot id: A0A379HEA6
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

28109:PNIG RS01490
gene id: 28109:PNIG_RS01490
uniprot id: A0A379HEG0
names: Similarity
messages: Belongs to the PRORSD1 family.

28109:PNIG RS01540
gene id: 28109:PNIG_RS01540
uniprot id: A0A379HEE9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

28109:PNIG RS05610
gene id: 28109:PNIG_RS05610
uniprot id: A0A379HDU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

28109:PNIG RS15015
gene id: 28109:PNIG_RS15015
uniprot id: A0A379H6Z7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

28109:PNIG RS05090
gene id: 28109:PNIG_RS05090
uniprot id: A0A379HCE7
names: Similarity
messages: Belongs to the RutC family.

28109:PNIG RS14355
gene id: 28109:PNIG_RS14355
uniprot id: A0A379H7A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

28109:PNIG RS03270
gene id: 28109:PNIG_RS03270
uniprot id: A0A379HF74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

28109:PNIG RS09470
gene id: 28109:PNIG_RS09470
uniprot id: A0A379HA29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

28109:PNIG RS01415
gene id: 28109:PNIG_RS01415
uniprot id: A0A379HG50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

28109:PNIG RS14555
gene id: 28109:PNIG_RS14555
uniprot id: A0A379H791
names: Similarity
messages: Belongs to the UPF0758 family.

28109:PNIG RS19285
gene id: 28109:PNIG_RS19285
uniprot id: A0A379I4J8
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

28109:PNIG RS01125
gene id: 28109:PNIG_RS01125
uniprot id: A0A379H6W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

28109:PNIG RS01450
gene id: 28109:PNIG_RS01450
uniprot id: A0A379HER6
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

28109:PNIG RS14420
gene id: 28109:PNIG_RS14420
uniprot id: A0A379H7H6
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS16465
gene id: 28109:PNIG_RS16465
uniprot id: A0A379HF32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

28109:PNIG RS01845
gene id: 28109:PNIG_RS01845
uniprot id: A0A379HE99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

28109:PNIG RS08560
gene id: 28109:PNIG_RS08560
uniprot id: A0A379HAJ5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

28109:PNIG RS16105
gene id: 28109:PNIG_RS16105
uniprot id: A0A379HF62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

28109:PNIG RS01170
gene id: 28109:PNIG_RS01170
uniprot id: A0A379H6Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

28109:PNIG RS05375
gene id: 28109:PNIG_RS05375
uniprot id: A0A379HC83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

28109:PNIG RS08140
gene id: 28109:PNIG_RS08140
uniprot id: A0A379HB86
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

28109:PNIG RS11070
gene id: 28109:PNIG_RS11070
uniprot id: A0A379H9K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

28109:PNIG RS00840
gene id: 28109:PNIG_RS00840
uniprot id: A0A379H6Q1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

28109:PNIG RS01320
gene id: 28109:PNIG_RS01320
uniprot id: A0A379H6T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

28109:PNIG RS12665
gene id: 28109:PNIG_RS12665
uniprot id: A0A379H8I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

28109:PNIG RS10240
gene id: 28109:PNIG_RS10240
uniprot id: A0A379H9K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

28109:PNIG RS00205
gene id: 28109:PNIG_RS00205
uniprot id: A0A379H624
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

28109:PNIG RS14130
gene id: 28109:PNIG_RS14130
uniprot id: A0A379H7L1
names: Subcellular Location Annotation
messages: Cytoplasm

28109:PNIG RS06185
gene id: 28109:PNIG_RS06185
uniprot id: A0A379HDJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

28109:PNIG RS03170
gene id: 28109:PNIG_RS03170
uniprot id: A0A379HF97
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

28109:PNIG RS11690
gene id: 28109:PNIG_RS11690
uniprot id: A0A379H8V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

28109:PNIG RS01175
gene id: 28109:PNIG_RS01175
uniprot id: A0A379H6M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

28109:PNIG RS05560
gene id: 28109:PNIG_RS05560
uniprot id: A0A379HDV2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

28109:PNIG RS13285
gene id: 28109:PNIG_RS13285
uniprot id: A0A379H7V9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS05410
gene id: 28109:PNIG_RS05410
uniprot id: A0A379HDX4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

28109:PNIG RS04875
gene id: 28109:PNIG_RS04875
uniprot id: A0A379HCL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

28109:PNIG RS01135
gene id: 28109:PNIG_RS01135
uniprot id: A0A379H8B7
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

28109:PNIG RS16505
gene id: 28109:PNIG_RS16505
uniprot id: A0A379HF61
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS05175
gene id: 28109:PNIG_RS05175
uniprot id: A0A379HCF6
names: Subunit
messages: Monomer.

28109:PNIG RS04370
gene id: 28109:PNIG_RS04370
uniprot id: A0A379HCV4
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

28109:PNIG RS00395
gene id: 28109:PNIG_RS00395
uniprot id: A0A379H6G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

28109:PNIG RS13995
gene id: 28109:PNIG_RS13995
uniprot id: A0A379H7Z2
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

28109:PNIG RS18730
gene id: 28109:PNIG_RS18730
uniprot id: A0A379I3Y0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

28109:PNIG RS14050
gene id: 28109:PNIG_RS14050
uniprot id: A0A379H7R6
names: Similarity
messages: Belongs to the BolA/IbaG family.

28109:PNIG RS03865
gene id: 28109:PNIG_RS03865
uniprot id: A0A379HD53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

28109:PNIG RS05230
gene id: 28109:PNIG_RS05230
uniprot id: A0A379HCC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

28109:PNIG RS10395
gene id: 28109:PNIG_RS10395
uniprot id: A0A379H9H1
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

28109:PNIG RS01875
gene id: 28109:PNIG_RS01875
uniprot id: A0A379HEK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

28109:PNIG RS07975
gene id: 28109:PNIG_RS07975
uniprot id: A0A379HAY4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

28109:PNIG RS16055
gene id: 28109:PNIG_RS16055
uniprot id: A0A379HF51
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

28109:PNIG RS08085
gene id: 28109:PNIG_RS08085
uniprot id: A0A379HB97
names: Similarity
messages: Belongs to the asparaginase 1 family.

28109:PNIG RS06485
gene id: 28109:PNIG_RS06485
uniprot id: A0A379HBQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

28109:PNIG RS15795
gene id: 28109:PNIG_RS15795
uniprot id: A0A379HGD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

28109:PNIG RS06010
gene id: 28109:PNIG_RS06010
uniprot id: A0A379HCE4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

28109:PNIG RS13720
gene id: 28109:PNIG_RS13720
uniprot id: A0A379H7N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

28109:PNIG RS17420
gene id: 28109:PNIG_RS17420
uniprot id: A0A379I3G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

28109:PNIG RS13215
gene id: 28109:PNIG_RS13215
uniprot id: A0A379H7Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

28109:PNIG RS10430
gene id: 28109:PNIG_RS10430
uniprot id: A0A379H9Q5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

28109:PNIG RS12660
gene id: 28109:PNIG_RS12660
uniprot id: A0A379H8Q2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

28109:PNIG RS14020
gene id: 28109:PNIG_RS14020
uniprot id: A0A379H7R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

28109:PNIG RS15930
gene id: 28109:PNIG_RS15930
uniprot id: A0A379HET5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS05235
gene id: 28109:PNIG_RS05235
uniprot id: A0A379HCE6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

28109:PNIG RS04080
gene id: 28109:PNIG_RS04080
uniprot id: A0A379HD07
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

28109:PNIG RS14755
gene id: 28109:PNIG_RS14755
uniprot id: A0A379H7C6
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

28109:PNIG RS16750
gene id: 28109:PNIG_RS16750
uniprot id: A0A379I4K1
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

28109:PNIG RS09615
gene id: 28109:PNIG_RS09615
uniprot id: A0A379HA74
names: Similarity
messages: Belongs to the AlaDH/PNT family.

28109:PNIG RS06160
gene id: 28109:PNIG_RS06160
uniprot id: A0A379HBZ2
names: Similarity
messages: Belongs to the WrbA family.

28109:PNIG RS01655
gene id: 28109:PNIG_RS01655
uniprot id: A0A379HEM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

28109:PNIG RS04360
gene id: 28109:PNIG_RS04360
uniprot id: A0A379HCU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

28109:PNIG RS07680
gene id: 28109:PNIG_RS07680
uniprot id: A0A379HBB0
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

28109:PNIG RS18660
gene id: 28109:PNIG_RS18660
uniprot id: A0A379I408
names: Similarity
messages: Belongs to the cytochrome b562 family.

28109:PNIG RS03855
gene id: 28109:PNIG_RS03855
uniprot id: A0A379HDI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

28109:PNIG RS12900
gene id: 28109:PNIG_RS12900
uniprot id: A0A379H855
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

28109:PNIG RS06060
gene id: 28109:PNIG_RS06060
uniprot id: A0A379HC12
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

28109:PNIG RS05265
gene id: 28109:PNIG_RS05265
uniprot id: A0A379HCQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

28109:PNIG RS15910
gene id: 28109:PNIG_RS15910
uniprot id: A0A379HET3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

28109:PNIG RS00740
gene id: 28109:PNIG_RS00740
uniprot id: A0A379H6N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

28109:PNIG RS05540
gene id: 28109:PNIG_RS05540
uniprot id: A0A379HCD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

28109:PNIG RS11400
gene id: 28109:PNIG_RS11400
uniprot id: A0A379H906
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

28109:PNIG RS14275
gene id: 28109:PNIG_RS14275
uniprot id: A0A379H7I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

28109:PNIG RS11915
gene id: 28109:PNIG_RS11915
uniprot id: A0A379H8X0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

28109:PNIG RS08040
gene id: 28109:PNIG_RS08040
uniprot id: A0A379HB32
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

28109:PNIG RS12640
gene id: 28109:PNIG_RS12640
uniprot id: A0A379H8F4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

28109:PNIG RS16250
gene id: 28109:PNIG_RS16250
uniprot id: A0A379HEZ7
names: Similarity
messages: Belongs to the Dps family.

28109:PNIG RS15455
gene id: 28109:PNIG_RS15455
uniprot id: A0A379HEK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

28109:PNIG RS04050
gene id: 28109:PNIG_RS04050
uniprot id: A0A379HD44
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

28109:PNIG RS05545
gene id: 28109:PNIG_RS05545
uniprot id: A0A379HCF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

28109:PNIG RS11870
gene id: 28109:PNIG_RS11870
uniprot id: A0A379H8P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

28109:PNIG RS10215
gene id: 28109:PNIG_RS10215
uniprot id: A0A379H9M7
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

28109:PNIG RS11245
gene id: 28109:PNIG_RS11245
uniprot id: A0A379H934
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

28109:PNIG RS11765
gene id: 28109:PNIG_RS11765
uniprot id: A0A379H8R5
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

28109:PNIG RS10895
gene id: 28109:PNIG_RS10895
uniprot id: A0A379H9G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

28109:PNIG RS05390
gene id: 28109:PNIG_RS05390
uniprot id: A0A379HCF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

28109:PNIG RS12600
gene id: 28109:PNIG_RS12600
uniprot id: A0A379H8D4
names: Similarity
messages: Belongs to the histone deacetylase family.

28109:PNIG RS06310
gene id: 28109:PNIG_RS06310
uniprot id: A0A379HBT6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28109:PNIG RS01380
gene id: 28109:PNIG_RS01380
uniprot id: A0A379HEH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

28109:PNIG RS13115
gene id: 28109:PNIG_RS13115
uniprot id: A0A379H897
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

28109:PNIG RS11625
gene id: 28109:PNIG_RS11625
uniprot id: A0A379H8X1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

28109:PNIG RS02990
gene id: 28109:PNIG_RS02990
uniprot id: A0A379HFC3
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

28109:PNIG RS03935
gene id: 28109:PNIG_RS03935
uniprot id: A0A379HDD0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS11845
gene id: 28109:PNIG_RS11845
uniprot id: A0A379H8S5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

28109:PNIG RS11615
gene id: 28109:PNIG_RS11615
uniprot id: A0A379H8U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

28109:PNIG RS05065
gene id: 28109:PNIG_RS05065
uniprot id: A0A379HCG1
names: Similarity
messages: Belongs to the elongation factor P family.

28109:PNIG RS00990
gene id: 28109:PNIG_RS00990
uniprot id: A0A379H6H5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

28109:PNIG RS05210
gene id: 28109:PNIG_RS05210
uniprot id: A0A379HCR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

28109:PNIG RS15385
gene id: 28109:PNIG_RS15385
uniprot id: A0A379HEL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

28109:PNIG RS12845
gene id: 28109:PNIG_RS12845
uniprot id: A0A379H874
names: Similarity
messages: Belongs to the UPF0234 family.

28109:PNIG RS12400
gene id: 28109:PNIG_RS12400
uniprot id: A0A379H8M8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28109:PNIG RS18285
gene id: 28109:PNIG_RS18285
uniprot id: A0A379I403
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

28109:PNIG RS14215
gene id: 28109:PNIG_RS14215
uniprot id: A0A379H7G1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

28109:PNIG RS09240
gene id: 28109:PNIG_RS09240
uniprot id: A0A379HAB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

28109:PNIG RS18670
gene id: 28109:PNIG_RS18670
uniprot id: A0A379I4A0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

28109:PNIG RS09220
gene id: 28109:PNIG_RS09220
uniprot id: A0A379HAD4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

28109:PNIG RS15510
gene id: 28109:PNIG_RS15510
uniprot id: A0A379HEN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

28109:PNIG RS04810
gene id: 28109:PNIG_RS04810
uniprot id: A0A379HCT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

28109:PNIG RS11300
gene id: 28109:PNIG_RS11300
uniprot id: A0A379H981
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

28109:PNIG RS11325
gene id: 28109:PNIG_RS11325
uniprot id: A0A379H9F9
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

28109:PNIG RS14040
gene id: 28109:PNIG_RS14040
uniprot id: A0A379H985
names: Similarity
messages: Belongs to the peptidase S1C family.

28109:PNIG RS04925
gene id: 28109:PNIG_RS04925
uniprot id: A0A379HCK4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

28109:PNIG RS00075
gene id: 28109:PNIG_RS00075
uniprot id: A0A379H607
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

28109:PNIG RS18690
gene id: 28109:PNIG_RS18690
uniprot id: A0A379I5N8
names: Subcellular Location Annotation
messages: Cytoplasm

28109:PNIG RS18820
gene id: 28109:PNIG_RS18820
uniprot id: A0A379I3Z8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

28109:PNIG RS15560
gene id: 28109:PNIG_RS15560
uniprot id: A0A379HEP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

28109:PNIG RS06475
gene id: 28109:PNIG_RS06475
uniprot id: A0A379HBW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

28109:PNIG RS13715
gene id: 28109:PNIG_RS13715
uniprot id: A0A379H7T7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

28109:PNIG RS06015
gene id: 28109:PNIG_RS06015
uniprot id: A0A379HC80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

28109:PNIG RS17990
gene id: 28109:PNIG_RS17990
uniprot id: A0A379I3J1
names: Similarity
messages: Belongs to the transglycosylase Slt family.

28109:PNIG RS07425
gene id: 28109:PNIG_RS07425
uniprot id: A0A379HCU6
names: Similarity
messages: Belongs to the YciI family.

28109:PNIG RS16975
gene id: 28109:PNIG_RS16975
uniprot id: A0A379I510
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

28109:PNIG RS17725
gene id: 28109:PNIG_RS17725
uniprot id: A0A379I3N7
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

28109:PNIG RS13410
gene id: 28109:PNIG_RS13410
uniprot id: A0A379H9J3
names: Similarity
messages: Belongs to the Gfa family.

28109:PNIG RS08175
gene id: 28109:PNIG_RS08175
uniprot id: A0A379HAS5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

28109:PNIG RS00250
gene id: 28109:PNIG_RS00250
uniprot id: A0A379H666
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

28109:PNIG RS06165
gene id: 28109:PNIG_RS06165
uniprot id: A0A379HC36
names: Similarity
messages: Belongs to the ArsC family.

28109:PNIG RS03695
gene id: 28109:PNIG_RS03695
uniprot id: A0A379HDJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

28109:PNIG RS00065
gene id: 28109:PNIG_RS00065
uniprot id: A0A379H634
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

28109:PNIG RS09755
gene id: 28109:PNIG_RS09755
uniprot id: A0A379H9U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

28109:PNIG RS17805
gene id: 28109:PNIG_RS17805
uniprot id: A0A379I3F8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28109:PNIG RS16435
gene id: 28109:PNIG_RS16435
uniprot id: A0A379HF65
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

28109:PNIG RS15220
gene id: 28109:PNIG_RS15220
uniprot id: A0A379H6W3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

28109:PNIG RS19275
gene id: 28109:PNIG_RS19275
uniprot id: A0A379I4A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

28109:PNIG RS07990
gene id: 28109:PNIG_RS07990
uniprot id: A0A379HB43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

28109:PNIG RS10145
gene id: 28109:PNIG_RS10145
uniprot id: A0A379H9M3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

28109:PNIG RS12755
gene id: 28109:PNIG_RS12755
uniprot id: A0A379H9W3
names: Similarity
messages: Belongs to the P(II) protein family.

28109:PNIG RS14715
gene id: 28109:PNIG_RS14715
uniprot id: A0A379H762
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

28109:PNIG RS14810
gene id: 28109:PNIG_RS14810
uniprot id: A0A379H710
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

28109:PNIG RS03575
gene id: 28109:PNIG_RS03575
uniprot id: A0A379HDK3
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

28109:PNIG RS16095
gene id: 28109:PNIG_RS16095
uniprot id: A0A379HEW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

28109:PNIG RS08230
gene id: 28109:PNIG_RS08230
uniprot id: A0A379HAS6
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS03940
gene id: 28109:PNIG_RS03940
uniprot id: A0A379HD39
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

28109:PNIG RS10910
gene id: 28109:PNIG_RS10910
uniprot id: A0A379HAW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

28109:PNIG RS11040
gene id: 28109:PNIG_RS11040
uniprot id: A0A379H9C0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

28109:PNIG RS13820
gene id: 28109:PNIG_RS13820
uniprot id: A0A379H7L3
names: Similarity
messages: Belongs to the phosphoribulokinase family.

28109:PNIG RS09400
gene id: 28109:PNIG_RS09400
uniprot id: A0A379HAB4
names: Similarity
messages: Belongs to the peptidase S41A family.

28109:PNIG RS03700
gene id: 28109:PNIG_RS03700
uniprot id: A0A379HD89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

28109:PNIG RS08310
gene id: 28109:PNIG_RS08310
uniprot id: A0A379HAQ1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

28109:PNIG RS08180
gene id: 28109:PNIG_RS08180
uniprot id: A0A379HAT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

28109:PNIG RS16985
gene id: 28109:PNIG_RS16985
uniprot id: A0A379I6C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

28109:PNIG RS08195
gene id: 28109:PNIG_RS08195
uniprot id: A0A379HAZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

28109:PNIG RS05615
gene id: 28109:PNIG_RS05615
uniprot id: A0A379HCK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS09635
gene id: 28109:PNIG_RS09635
uniprot id: A0A379HAC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

28109:PNIG RS12175
gene id: 28109:PNIG_RS12175
uniprot id: A0A379H8R6
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

28109:PNIG RS17835
gene id: 28109:PNIG_RS17835
uniprot id: A0A379I3F5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

28109:PNIG RS03245
gene id: 28109:PNIG_RS03245
uniprot id: A0A379HDJ5
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

28109:PNIG RS04430
gene id: 28109:PNIG_RS04430
uniprot id: A0A379HD19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

28109:PNIG RS14760
gene id: 28109:PNIG_RS14760
uniprot id: A0A379H719
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

28109:PNIG RS01725
gene id: 28109:PNIG_RS01725
uniprot id: A0A379HEN3
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

28109:PNIG RS00670
gene id: 28109:PNIG_RS00670
uniprot id: A0A379H6L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

28109:PNIG RS06425
gene id: 28109:PNIG_RS06425
uniprot id: A0A379HBU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

28109:PNIG RS16195
gene id: 28109:PNIG_RS16195
uniprot id: A0A379HEY3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

28109:PNIG RS08005
gene id: 28109:PNIG_RS08005
uniprot id: A0A379HAV7
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

28109:PNIG RS08545
gene id: 28109:PNIG_RS08545
uniprot id: A0A379HB14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

28109:PNIG RS03560
gene id: 28109:PNIG_RS03560
uniprot id: A0A379HDD8
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.

28109:PNIG RS15450
gene id: 28109:PNIG_RS15450
uniprot id: A0A379HEM8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

28109:PNIG RS00220
gene id: 28109:PNIG_RS00220
uniprot id: A0A379H7U5
names: Similarity
messages: Belongs to the PspA/IM30 family.

28109:PNIG RS19295
gene id: 28109:PNIG_RS19295
uniprot id: A0A379I4K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

28109:PNIG RS15200
gene id: 28109:PNIG_RS15200
uniprot id: A0A379H776
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

28109:PNIG RS01225
gene id: 28109:PNIG_RS01225
uniprot id: A0A379H6N3
names: Similarity
messages: Belongs to the HSP15 family.

28109:PNIG RS02965
gene id: 28109:PNIG_RS02965
uniprot id: A0A379HDM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

28109:PNIG RS09365
gene id: 28109:PNIG_RS09365
uniprot id: A0A379HAI0
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS19495
gene id: 28109:PNIG_RS19495
uniprot id: A0A379I4C1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

28109:PNIG RS12645
gene id: 28109:PNIG_RS12645
uniprot id: A0A379H8B1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

28109:PNIG RS07395
gene id: 28109:PNIG_RS07395
uniprot id: A0A379HB69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

28109:PNIG RS18650
gene id: 28109:PNIG_RS18650
uniprot id: A0A379I3W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

28109:PNIG RS12505
gene id: 28109:PNIG_RS12505
uniprot id: A0A379H8E1
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS00790
gene id: 28109:PNIG_RS00790
uniprot id: A0A379H6P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

28109:PNIG RS17735
gene id: 28109:PNIG_RS17735
uniprot id: A0A379I3D3
names: Function
messages: May be involved in the biogenesis of curli organelles.

28109:PNIG RS16855
gene id: 28109:PNIG_RS16855
uniprot id: A0A379I4J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

28109:PNIG RS01180
gene id: 28109:PNIG_RS01180
uniprot id: A0A379H6X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

28109:PNIG RS18495
gene id: 28109:PNIG_RS18495
uniprot id: A0A379I3T2
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS09640
gene id: 28109:PNIG_RS09640
uniprot id: A0A379HA66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

28109:PNIG RS14770
gene id: 28109:PNIG_RS14770
uniprot id: A0A379H747
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

28109:PNIG RS14340
gene id: 28109:PNIG_RS14340
uniprot id: A0A379H922
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

28109:PNIG RS18605
gene id: 28109:PNIG_RS18605
uniprot id: A0A379I3X0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28109:PNIG RS08540
gene id: 28109:PNIG_RS08540
uniprot id: A0A379HC90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

28109:PNIG RS07695
gene id: 28109:PNIG_RS07695
uniprot id: A0A379HB24
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

28109:PNIG RS05260
gene id: 28109:PNIG_RS05260
uniprot id: A0A379HE07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

28109:PNIG RS10565
gene id: 28109:PNIG_RS10565
uniprot id: A0A379H9G5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

28109:PNIG RS11590
gene id: 28109:PNIG_RS11590
uniprot id: A0A379H8X2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS16635
gene id: 28109:PNIG_RS16635
uniprot id: A0A379I4F4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28109:PNIG RS11700
gene id: 28109:PNIG_RS11700
uniprot id: A0A379HAG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

28109:PNIG RS08160
gene id: 28109:PNIG_RS08160
uniprot id: A0A379HAT2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS11920
gene id: 28109:PNIG_RS11920
uniprot id: A0A379H8Q7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

28109:PNIG RS13490
gene id: 28109:PNIG_RS13490
uniprot id: A0A379H7U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

28109:PNIG RS04565
gene id: 28109:PNIG_RS04565
uniprot id: A0A379HCR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

28109:PNIG RS11760
gene id: 28109:PNIG_RS11760
uniprot id: A0A379H907
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

28109:PNIG RS10465
gene id: 28109:PNIG_RS10465
uniprot id: A0A379H9I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

28109:PNIG RS12720
gene id: 28109:PNIG_RS12720
uniprot id: A0A379H885
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

28109:PNIG RS03550
gene id: 28109:PNIG_RS03550
uniprot id: A0A379HDM1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

28109:PNIG RS11475
gene id: 28109:PNIG_RS11475
uniprot id: A0A379H8Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

28109:PNIG RS03685
gene id: 28109:PNIG_RS03685
uniprot id: A0A379HDA4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS05395
gene id: 28109:PNIG_RS05395
uniprot id: A0A379HCI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

28109:PNIG RS15480
gene id: 28109:PNIG_RS15480
uniprot id: A0A379HET7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

28109:PNIG RS11345
gene id: 28109:PNIG_RS11345
uniprot id: A0A379H918
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

28109:PNIG RS14975
gene id: 28109:PNIG_RS14975
uniprot id: A0A379H748
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS09085
gene id: 28109:PNIG_RS09085
uniprot id: A0A379HA99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

28109:PNIG RS03595
gene id: 28109:PNIG_RS03595
uniprot id: A0A379HDF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

28109:PNIG RS05405
gene id: 28109:PNIG_RS05405
uniprot id: A0A379HCB4
names: Similarity
messages: Belongs to the peptidase S16 family.

28109:PNIG RS14395
gene id: 28109:PNIG_RS14395
uniprot id: A0A379H7N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

28109:PNIG RS14200
gene id: 28109:PNIG_RS14200
uniprot id: A0A379H7P0
names: Similarity
messages: Belongs to the UPF0438 family.

28109:PNIG RS14520
gene id: 28109:PNIG_RS14520
uniprot id: A0A379H7D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

28109:PNIG RS14545
gene id: 28109:PNIG_RS14545
uniprot id: A0A379H7G8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

28109:PNIG RS07445
gene id: 28109:PNIG_RS07445
uniprot id: A0A379HB53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

28109:PNIG RS15520
gene id: 28109:PNIG_RS15520
uniprot id: A0A379HEL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

28109:PNIG RS13255
gene id: 28109:PNIG_RS13255
uniprot id: A0A379H835
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

28109:PNIG RS07430
gene id: 28109:PNIG_RS07430
uniprot id: A0A379HBN0
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS13250
gene id: 28109:PNIG_RS13250
uniprot id: A0A379H856
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

28109:PNIG RS09875
gene id: 28109:PNIG_RS09875
uniprot id: A0A379H9U5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

28109:PNIG RS00045
gene id: 28109:PNIG_RS00045
uniprot id: A0A379H7R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

28109:PNIG RS04340
gene id: 28109:PNIG_RS04340
uniprot id: A0A379HCY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

28109:PNIG RS18370
gene id: 28109:PNIG_RS18370
uniprot id: A0A379I3R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

28109:PNIG RS06865
gene id: 28109:PNIG_RS06865
uniprot id: A0A379HBP6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

28109:PNIG RS10930
gene id: 28109:PNIG_RS10930
uniprot id: A0A379H979
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

28109:PNIG RS01195
gene id: 28109:PNIG_RS01195
uniprot id: A0A379H6N7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

28109:PNIG RS15000
gene id: 28109:PNIG_RS15000
uniprot id: A0A379H775
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

28109:PNIG RS16085
gene id: 28109:PNIG_RS16085
uniprot id: A0A379HEZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

28109:PNIG RS09260
gene id: 28109:PNIG_RS09260
uniprot id: A0A379HBU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

28109:PNIG RS04720
gene id: 28109:PNIG_RS04720
uniprot id: A0A379HCN7
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

28109:PNIG RS18950
gene id: 28109:PNIG_RS18950
uniprot id: A0A379I465
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28109:PNIG RS11970
gene id: 28109:PNIG_RS11970
uniprot id: A0A379H8V7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS01470
gene id: 28109:PNIG_RS01470
uniprot id: A0A379HES8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

28109:PNIG RS04635
gene id: 28109:PNIG_RS04635
uniprot id: A0A379HCY7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

28109:PNIG RS14285
gene id: 28109:PNIG_RS14285
uniprot id: A0A379H7C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

28109:PNIG RS12035
gene id: 28109:PNIG_RS12035
uniprot id: A0A379H8P8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

28109:PNIG RS05590
gene id: 28109:PNIG_RS05590
uniprot id: A0A379HCC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

28109:PNIG RS05110
gene id: 28109:PNIG_RS05110
uniprot id: A0A379HCN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

28109:PNIG RS05245
gene id: 28109:PNIG_RS05245
uniprot id: A0A379HCL6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

28109:PNIG RS05345
gene id: 28109:PNIG_RS05345
uniprot id: A0A379HCJ0
names: Similarity
messages: Belongs to the UPF0250 family.

28109:PNIG RS15935
gene id: 28109:PNIG_RS15935
uniprot id: A0A379HET4
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

28109:PNIG RS03605
gene id: 28109:PNIG_RS03605
uniprot id: A0A379HDB0
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

28109:PNIG RS08285
gene id: 28109:PNIG_RS08285
uniprot id: A0A379HCE1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

28109:PNIG RS19485
gene id: 28109:PNIG_RS19485
uniprot id: A0A379I4G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

28109:PNIG RS00650
gene id: 28109:PNIG_RS00650
uniprot id: A0A379H6I2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS15790
gene id: 28109:PNIG_RS15790
uniprot id: A0A379HF25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

28109:PNIG RS05855
gene id: 28109:PNIG_RS05855
uniprot id: A0A379HCH5
names: Similarity
messages: Belongs to the CopC family.

28109:PNIG RS18970
gene id: 28109:PNIG_RS18970
uniprot id: A0A379I418
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

28109:PNIG RS02920
gene id: 28109:PNIG_RS02920
uniprot id: A0A379HDN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

28109:PNIG RS03950
gene id: 28109:PNIG_RS03950
uniprot id: A0A379HEU2
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

28109:PNIG RS00730
gene id: 28109:PNIG_RS00730
uniprot id: A0A379H6F7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

28109:PNIG RS04930
gene id: 28109:PNIG_RS04930
uniprot id: A0A379HCP0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

28109:PNIG RS00560
gene id: 28109:PNIG_RS00560
uniprot id: A0A379H689
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

28109:PNIG RS01555
gene id: 28109:PNIG_RS01555
uniprot id: A0A379HEP8
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

28109:PNIG RS04200
gene id: 28109:PNIG_RS04200
uniprot id: A0A379HD65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

28109:PNIG RS05530
gene id: 28109:PNIG_RS05530
uniprot id: A0A379HC72
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

28109:PNIG RS01130
gene id: 28109:PNIG_RS01130
uniprot id: A0A379H704
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

28109:PNIG RS14240
gene id: 28109:PNIG_RS14240
uniprot id: A0A379H951
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

28109:PNIG RS01265
gene id: 28109:PNIG_RS01265
uniprot id: A0A379H6R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

28109:PNIG RS15445
gene id: 28109:PNIG_RS15445
uniprot id: A0A379HEU6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

28109:PNIG RS18645
gene id: 28109:PNIG_RS18645
uniprot id: A0A379I478
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

28109:PNIG RS09255
gene id: 28109:PNIG_RS09255
uniprot id: A0A379HA71
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

28109:PNIG RS04880
gene id: 28109:PNIG_RS04880
uniprot id: A0A379HCQ2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

28109:PNIG RS08205
gene id: 28109:PNIG_RS08205
uniprot id: A0A379HAR2
names: Similarity
messages: Belongs to the CvfB family.

28109:PNIG RS09865
gene id: 28109:PNIG_RS09865
uniprot id: A0A379HA20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MerP family.
messages: Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
messages: Monomer.
messages: Periplasm

28109:PNIG RS05595
gene id: 28109:PNIG_RS05595
uniprot id: A0A379HCE9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28109:PNIG RS14350
gene id: 28109:PNIG_RS14350
uniprot id: A0A379H7K8
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

28109:PNIG RS06205
gene id: 28109:PNIG_RS06205
uniprot id: A0A379HBW6
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

28109:PNIG RS04410
gene id: 28109:PNIG_RS04410
uniprot id: A0A379HCU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

28109:PNIG RS09435
gene id: 28109:PNIG_RS09435
uniprot id: A0A379HA96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

28109:PNIG RS16125
gene id: 28109:PNIG_RS16125
uniprot id: A0A379HEX7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

28109:PNIG RS00755
gene id: 28109:PNIG_RS00755
uniprot id: A0A379H6E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

28109:PNIG RS12590
gene id: 28109:PNIG_RS12590
uniprot id: A0A379H8H3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

28109:PNIG RS04265
gene id: 28109:PNIG_RS04265
uniprot id: A0A379HCX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

28109:PNIG RS09110
gene id: 28109:PNIG_RS09110
uniprot id: A0A379HBX7
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

28109:PNIG RS14705
gene id: 28109:PNIG_RS14705
uniprot id: A0A379H7D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

28109:PNIG RS00480
gene id: 28109:PNIG_RS00480
uniprot id: A0A379H687
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

28109:PNIG RS17605
gene id: 28109:PNIG_RS17605
uniprot id: A0A379I3P1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

28109:PNIG RS13640
gene id: 28109:PNIG_RS13640
uniprot id: A0A379H7P6
names: Similarity
messages: Belongs to the Dps family.

28109:PNIG RS07665
gene id: 28109:PNIG_RS07665
uniprot id: A0A379HB52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Membrane

28109:PNIG RS12110
gene id: 28109:PNIG_RS12110
uniprot id: A0A379H8L9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

28109:PNIG RS15400
gene id: 28109:PNIG_RS15400
uniprot id: A0A379HEI5
names: Similarity
messages: Belongs to the RutC family.

28109:PNIG RS15390
gene id: 28109:PNIG_RS15390
uniprot id: A0A379HEJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

28109:PNIG RS04185
gene id: 28109:PNIG_RS04185
uniprot id: A0A379HD14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

28109:PNIG RS01165
gene id: 28109:PNIG_RS01165
uniprot id: A0A379H6N5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

28109:PNIG RS03265
gene id: 28109:PNIG_RS03265
uniprot id: A0A379HDJ6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

28109:PNIG RS04195
gene id: 28109:PNIG_RS04195
uniprot id: A0A379HDB5
names: Subcellular Location Annotation
messages: Cytoplasm

28109:PNIG RS13210
gene id: 28109:PNIG_RS13210
uniprot id: A0A379H822
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

28109:PNIG RS12735
gene id: 28109:PNIG_RS12735
uniprot id: A0A379H8F9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

28109:PNIG RS03290
gene id: 28109:PNIG_RS03290
uniprot id: A0A379HDH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

28109:PNIG RS18005
gene id: 28109:PNIG_RS18005
uniprot id: A0A379I3W4
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

28109:PNIG RS06405
gene id: 28109:PNIG_RS06405
uniprot id: A0A379HC07
names: Subcellular Location Annotation
messages: Cytoplasm

28109:PNIG RS19505
gene id: 28109:PNIG_RS19505
uniprot id: A0A379I4F5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS14270
gene id: 28109:PNIG_RS14270
uniprot id: A0A379H7K6
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

28109:PNIG RS11795
gene id: 28109:PNIG_RS11795
uniprot id: A0A379H8T5
names: Similarity
messages: Belongs to the PspA/IM30 family.

28109:PNIG RS13035
gene id: 28109:PNIG_RS13035
uniprot id: A0A379H894
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

28109:PNIG RS16540
gene id: 28109:PNIG_RS16540
uniprot id: A0A379HF55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

28109:PNIG RS16285
gene id: 28109:PNIG_RS16285
uniprot id: A0A379HF33
names: Subcellular Location Annotation
messages: Membrane

28109:PNIG RS17115
gene id: 28109:PNIG_RS17115
uniprot id: A0A379I312
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

28109:PNIG RS19055
gene id: 28109:PNIG_RS19055
uniprot id: A0A379I441
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

28109:PNIG RS14310
gene id: 28109:PNIG_RS14310
uniprot id: A0A379H7E1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

28109:PNIG RS02230
gene id: 28109:PNIG_RS02230
uniprot id: A0A379HEA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

28109:PNIG RS07595
gene id: 28109:PNIG_RS07595
uniprot id: A0A379HB44
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

28109:PNIG RS15525
gene id: 28109:PNIG_RS15525
uniprot id: A0A379HEK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

28109:PNIG RS02130
gene id: 28109:PNIG_RS02130
uniprot id: A0A379HEF7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

28109:PNIG RS11775
gene id: 28109:PNIG_RS11775
uniprot id: A0A379H8U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

28109:PNIG RS05565
gene id: 28109:PNIG_RS05565
uniprot id: A0A379HCL2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

28109:PNIG RS04215
gene id: 28109:PNIG_RS04215
uniprot id: A0A379HCY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

28109:PNIG RS14960
gene id: 28109:PNIG_RS14960
uniprot id: A0A379H708
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

28109:PNIG RS11965
gene id: 28109:PNIG_RS11965
uniprot id: A0A379H8W5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

28109:PNIG RS14195
gene id: 28109:PNIG_RS14195
uniprot id: A0A379H7T8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

28109:PNIG RS06930
gene id: 28109:PNIG_RS06930
uniprot id: A0A379HD37
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

28109:PNIG RS17640
gene id: 28109:PNIG_RS17640
uniprot id: A0A379I3F2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

28109:PNIG RS03275
gene id: 28109:PNIG_RS03275
uniprot id: A0A379HDV6
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

28109:PNIG RS07720
gene id: 28109:PNIG_RS07720
uniprot id: A0A379HB39
names: Similarity
messages: Belongs to the peptidase S49 family.

28109:PNIG RS03300
gene id: 28109:PNIG_RS03300
uniprot id: A0A379HDK9
names: Similarity
messages: Belongs to the peptidase M17 family.

28109:PNIG RS06900
gene id: 28109:PNIG_RS06900
uniprot id: A0A379HBG0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

28109:PNIG RS15730
gene id: 28109:PNIG_RS15730
uniprot id: A0A379HEP6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

28109:PNIG RS02090
gene id: 28109:PNIG_RS02090
uniprot id: A0A379HE39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.