278992:SAM23877 RS00455
gene id: 278992:SAM23877_RS00455
uniprot id: Q1RQY8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

278992:SAM23877 RS09140
gene id: 278992:SAM23877_RS09140
uniprot id: A0A0K2AQA2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

278992:SAM23877 RS01535
gene id: 278992:SAM23877_RS01535
uniprot id: A0A0K2AKH7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

278992:SAM23877 RS10145
gene id: 278992:SAM23877_RS10145
uniprot id: A0A0K2AQD2
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

278992:SAM23877 RS09045
gene id: 278992:SAM23877_RS09045
uniprot id: A0A0K2APQ8
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

278992:SAM23877 RS10135
gene id: 278992:SAM23877_RS10135
uniprot id: A0A0K2AQM2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

278992:SAM23877 RS26135
gene id: 278992:SAM23877_RS26135
uniprot id: A0A0K2B082
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS33995
gene id: 278992:SAM23877_RS33995
uniprot id: A0ACE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

278992:SAM23877 RS28335
gene id: 278992:SAM23877_RS28335
uniprot id: A0A0K2B0Y2
names: Similarity
messages: Belongs to the IucA/IucC family.

278992:SAM23877 RS24350
gene id: 278992:SAM23877_RS24350
uniprot id: A0A0K2AZC0
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

278992:SAM23877 RS14495
gene id: 278992:SAM23877_RS14495
uniprot id: A0A0K2AT25
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

278992:SAM23877 RS02395
gene id: 278992:SAM23877_RS02395
uniprot id: A3KIF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

278992:SAM23877 RS21865
gene id: 278992:SAM23877_RS21865
uniprot id: A0A0K2AXA0
names: Similarity
messages: Belongs to the peptidase C40 family.

278992:SAM23877 RS21475
gene id: 278992:SAM23877_RS21475
uniprot id: A0A0K2AXF1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS05885
gene id: 278992:SAM23877_RS05885
uniprot id: A3KKE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

278992:SAM23877 RS06315
gene id: 278992:SAM23877_RS06315
uniprot id: A3KKN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

278992:SAM23877 RS24490
gene id: 278992:SAM23877_RS24490
uniprot id: A0A0K2AZ75
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

278992:SAM23877 RS28015
gene id: 278992:SAM23877_RS28015
uniprot id: A0A0K2B1B7
names: Similarity
messages: Belongs to the CdaR family.

278992:SAM23877 RS25225
gene id: 278992:SAM23877_RS25225
uniprot id: A0A0K2AZG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

278992:SAM23877 RS08410
gene id: 278992:SAM23877_RS08410
uniprot id: A0A0K2APL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

278992:SAM23877 RS19810
gene id: 278992:SAM23877_RS19810
uniprot id: A0A0K2AW26
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

278992:SAM23877 RS17265
gene id: 278992:SAM23877_RS17265
uniprot id: A0A0K2AV45
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

278992:SAM23877 RS23060
gene id: 278992:SAM23877_RS23060
uniprot id: A0A0K2AXZ5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

278992:SAM23877 RS14800
gene id: 278992:SAM23877_RS14800
uniprot id: A0A0K2AT59
names: Similarity
messages: Belongs to the CFA/CMAS family.

278992:SAM23877 RS31550
gene id: 278992:SAM23877_RS31550
uniprot id: A0ADS8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

278992:SAM23877 RS09315
gene id: 278992:SAM23877_RS09315
uniprot id: A0A0K2AQD6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

278992:SAM23877 RS19595
gene id: 278992:SAM23877_RS19595
uniprot id: A0A0K2AWA3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

278992:SAM23877 RS21750
gene id: 278992:SAM23877_RS21750
uniprot id: A0A0K2AWX9
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

278992:SAM23877 RS11710
gene id: 278992:SAM23877_RS11710
uniprot id: A0A0K2ARW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS28610
gene id: 278992:SAM23877_RS28610
uniprot id: A0A0K2B135
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

278992:SAM23877 RS26730
gene id: 278992:SAM23877_RS26730
uniprot id: A0A0K2B068
names: Similarity
messages: Belongs to the cytochrome P450 family.

278992:SAM23877 RS10045
gene id: 278992:SAM23877_RS10045
uniprot id: A0A0K2AQ03
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS17715
gene id: 278992:SAM23877_RS17715
uniprot id: A0A0K2AV51
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS17115
gene id: 278992:SAM23877_RS17115
uniprot id: A0A0K2AUS9
names: Similarity
messages: Belongs to the GARS family.

278992:SAM23877 RS08835
gene id: 278992:SAM23877_RS08835
uniprot id: A0A0K2APN6
names: Similarity
messages: Belongs to the peptidase S8 family.

278992:SAM23877 RS01255
gene id: 278992:SAM23877_RS01255
uniprot id: Q1RR95
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

278992:SAM23877 RS31990
gene id: 278992:SAM23877_RS31990
uniprot id: A0ADJ1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

278992:SAM23877 RS32060
gene id: 278992:SAM23877_RS32060
uniprot id: A0ADH7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

278992:SAM23877 RS04980
gene id: 278992:SAM23877_RS04980
uniprot id: A3KJW6
names: Similarity
messages: Belongs to the CdaR family.

278992:SAM23877 RS02970
gene id: 278992:SAM23877_RS02970
uniprot id: A3KIR2
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS10545
gene id: 278992:SAM23877_RS10545
uniprot id: A0A0K2AQ99
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

278992:SAM23877 RS15645
gene id: 278992:SAM23877_RS15645
uniprot id: A0A0K2ATX5
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS25240
gene id: 278992:SAM23877_RS25240
uniprot id: A0A0K2AZM5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

278992:SAM23877 RS09740
gene id: 278992:SAM23877_RS09740
uniprot id: A0A0K2AQ50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

278992:SAM23877 RS30365
gene id: 278992:SAM23877_RS30365
uniprot id: A0A0K2B2K3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

278992:SAM23877 RS06900
gene id: 278992:SAM23877_RS06900
uniprot id: A3KKZ7
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

278992:SAM23877 RS06750
gene id: 278992:SAM23877_RS06750
uniprot id: A3KKW6
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS23895
gene id: 278992:SAM23877_RS23895
uniprot id: A0A0K2AY91
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

278992:SAM23877 RS16385
gene id: 278992:SAM23877_RS16385
uniprot id: A0A0K2AU71
names: Subcellular Location Annotation
messages: Cell membrane

278992:SAM23877 RS13190
gene id: 278992:SAM23877_RS13190
uniprot id: A0A0K2ASE6
names: Similarity
messages: Belongs to the TPP enzyme family.

278992:SAM23877 RS03505
gene id: 278992:SAM23877_RS03505
uniprot id: A3KJ19
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

278992:SAM23877 RS00230
gene id: 278992:SAM23877_RS00230
uniprot id: Q1RR38
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

278992:SAM23877 RS09480
gene id: 278992:SAM23877_RS09480
uniprot id: A0A0K2APQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

278992:SAM23877 RS32610
gene id: 278992:SAM23877_RS32610
uniprot id: A0AD65
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

278992:SAM23877 RS24285
gene id: 278992:SAM23877_RS24285
uniprot id: A0A0K2AYX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

278992:SAM23877 RS07885
gene id: 278992:SAM23877_RS07885
uniprot id: A0A0K2ANR4
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS32900
gene id: 278992:SAM23877_RS32900
uniprot id: A0AD08
names: Similarity
messages: Belongs to the FemABX family.

278992:SAM23877 RS03815
gene id: 278992:SAM23877_RS03815
uniprot id: A3KJ82
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

278992:SAM23877 RS17545
gene id: 278992:SAM23877_RS17545
uniprot id: A0A0K2AUD2
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS22110
gene id: 278992:SAM23877_RS22110
uniprot id: A0A0K2AX50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

278992:SAM23877 RS07020
gene id: 278992:SAM23877_RS07020
uniprot id: A0A0K2ANK3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

278992:SAM23877 RS30265
gene id: 278992:SAM23877_RS30265
uniprot id: A0A0K2B2U1
names: Similarity
messages: Belongs to the YciI family.

278992:SAM23877 RS19395
gene id: 278992:SAM23877_RS19395
uniprot id: A0A0K2AVY2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

278992:SAM23877 RS16365
gene id: 278992:SAM23877_RS16365
uniprot id: A0A0K2AU46
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

278992:SAM23877 RS03710
gene id: 278992:SAM23877_RS03710
uniprot id: A3KJ62
names: Similarity
messages: Belongs to the catalase family.

278992:SAM23877 RS18155
gene id: 278992:SAM23877_RS18155
uniprot id: A0A0K2AV58
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

278992:SAM23877 RS19170
gene id: 278992:SAM23877_RS19170
uniprot id: A0A0K2AVP7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

278992:SAM23877 RS21730
gene id: 278992:SAM23877_RS21730
uniprot id: A0A0K2AXJ7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

278992:SAM23877 RS11670
gene id: 278992:SAM23877_RS11670
uniprot id: A0A0K2ARC0
names: Similarity
messages: Belongs to the aldose epimerase family.

278992:SAM23877 RS12860
gene id: 278992:SAM23877_RS12860
uniprot id: A0A0K2ARM3
names: Similarity
messages: Belongs to the melC1 family.

278992:SAM23877 RS06085
gene id: 278992:SAM23877_RS06085
uniprot id: A3KKI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

278992:SAM23877 RS04520
gene id: 278992:SAM23877_RS04520
uniprot id: A0A0K2AMJ6
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS05840
gene id: 278992:SAM23877_RS05840
uniprot id: A3KKD6
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

278992:SAM23877 RS21205
gene id: 278992:SAM23877_RS21205
uniprot id: A0A0K2AX24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

278992:SAM23877 RS16465
gene id: 278992:SAM23877_RS16465
uniprot id: A0A0K2ATU9
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS19605
gene id: 278992:SAM23877_RS19605
uniprot id: A0A0K2AW21
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

278992:SAM23877 RS17925
gene id: 278992:SAM23877_RS17925
uniprot id: A0A0K2AV92
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

278992:SAM23877 RS28720
gene id: 278992:SAM23877_RS28720
uniprot id: A0A0K2B1Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS25970
gene id: 278992:SAM23877_RS25970
uniprot id: A0A0K2AZY5
names: Similarity
messages: Belongs to the AHA1 family.

278992:SAM23877 RS26145
gene id: 278992:SAM23877_RS26145
uniprot id: A0A0K2B016
names: Similarity
messages: Belongs to the peptidase M1 family.

278992:SAM23877 RS25400
gene id: 278992:SAM23877_RS25400
uniprot id: A0A0K2AZJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

278992:SAM23877 RS12890
gene id: 278992:SAM23877_RS12890
uniprot id: A0A0K2AS85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

278992:SAM23877 RS18560
gene id: 278992:SAM23877_RS18560
uniprot id: A0A0K2AVA7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS09810
gene id: 278992:SAM23877_RS09810
uniprot id: A0A0K2AQN0
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS15720
gene id: 278992:SAM23877_RS15720
uniprot id: A0A0K2ATR9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

278992:SAM23877 RS27255
gene id: 278992:SAM23877_RS27255
uniprot id: A0A0K2B101
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

278992:SAM23877 RS21370
gene id: 278992:SAM23877_RS21370
uniprot id: A0A0K2AXD3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

278992:SAM23877 RS35410
gene id: 278992:SAM23877_RS35410
uniprot id: Q1RQS9
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

278992:SAM23877 RS04945
gene id: 278992:SAM23877_RS04945
uniprot id: A3KJV9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

278992:SAM23877 RS06390
gene id: 278992:SAM23877_RS06390
uniprot id: A3KKP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS15260
gene id: 278992:SAM23877_RS15260
uniprot id: A0A0K2ATP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

278992:SAM23877 RS07365
gene id: 278992:SAM23877_RS07365
uniprot id: A0A0K2AP78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

278992:SAM23877 RS22005
gene id: 278992:SAM23877_RS22005
uniprot id: A0A0K2AXC7
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

278992:SAM23877 RS06705
gene id: 278992:SAM23877_RS06705
uniprot id: A3KKV7
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

278992:SAM23877 RS27500
gene id: 278992:SAM23877_RS27500
uniprot id: A0A0K2B152
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.

278992:SAM23877 RS23135
gene id: 278992:SAM23877_RS23135
uniprot id: A0A0K2AY09
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

278992:SAM23877 RS22255
gene id: 278992:SAM23877_RS22255
uniprot id: A0A0K2AX79
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

278992:SAM23877 RS14230
gene id: 278992:SAM23877_RS14230
uniprot id: A0A0K2AT18
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

278992:SAM23877 RS16750
gene id: 278992:SAM23877_RS16750
uniprot id: A0A0K2AUV5
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS15100
gene id: 278992:SAM23877_RS15100
uniprot id: A0A0K2ATC4
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS12050
gene id: 278992:SAM23877_RS12050
uniprot id: A0A0K2AS23
names: Similarity
messages: Belongs to the Fur family.

278992:SAM23877 RS17945
gene id: 278992:SAM23877_RS17945
uniprot id: A0A0K2AUL4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

278992:SAM23877 RS09845
gene id: 278992:SAM23877_RS09845
uniprot id: A0A0K2AQ71
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

278992:SAM23877 RS11785
gene id: 278992:SAM23877_RS11785
uniprot id: A0A0K2ARE1
names: Similarity
messages: Belongs to the peptidase S8 family.

278992:SAM23877 RS33030
gene id: 278992:SAM23877_RS33030
uniprot id: A0ACY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

278992:SAM23877 RS11145
gene id: 278992:SAM23877_RS11145
uniprot id: A0A0K2ARG3
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

278992:SAM23877 RS26785
gene id: 278992:SAM23877_RS26785
uniprot id: A0A0K2B0R1
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

278992:SAM23877 RS06895
gene id: 278992:SAM23877_RS06895
uniprot id: A3KKZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

278992:SAM23877 RS29550
gene id: 278992:SAM23877_RS29550
uniprot id: A0A0K2B2A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS27910
gene id: 278992:SAM23877_RS27910
uniprot id: A0A0K2B0L1
names: Similarity
messages: Belongs to the TPP enzyme family.

278992:SAM23877 RS09585
gene id: 278992:SAM23877_RS09585
uniprot id: A0A0K2AQA8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

278992:SAM23877 RS02780
gene id: 278992:SAM23877_RS02780
uniprot id: A0A0K2ALB1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

278992:SAM23877 RS07235
gene id: 278992:SAM23877_RS07235
uniprot id: A0A0K2ANP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

278992:SAM23877 RS21595
gene id: 278992:SAM23877_RS21595
uniprot id: A0A0K2AXB6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS09100
gene id: 278992:SAM23877_RS09100
uniprot id: A0A0K2APU0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS24520
gene id: 278992:SAM23877_RS24520
uniprot id: A0A0K2AZF4
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

278992:SAM23877 RS06080
gene id: 278992:SAM23877_RS06080
uniprot id: A3KKI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

278992:SAM23877 RS10680
gene id: 278992:SAM23877_RS10680
uniprot id: A0A0K2AQX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

278992:SAM23877 RS21260
gene id: 278992:SAM23877_RS21260
uniprot id: A0A0K2AWZ6
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS05635
gene id: 278992:SAM23877_RS05635
uniprot id: A3KK96
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

278992:SAM23877 RS25700
gene id: 278992:SAM23877_RS25700
uniprot id: A0A0K2AZR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS12000
gene id: 278992:SAM23877_RS12000
uniprot id: A0A0K2ARQ8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

278992:SAM23877 RS08800
gene id: 278992:SAM23877_RS08800
uniprot id: A0A0K2APT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

278992:SAM23877 RS23005
gene id: 278992:SAM23877_RS23005
uniprot id: A0A0K2AY53
names: Similarity
messages: Belongs to the FBPase class 2 family.

278992:SAM23877 RS07055
gene id: 278992:SAM23877_RS07055
uniprot id: A0A0K2ANU2
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

278992:SAM23877 RS25975
gene id: 278992:SAM23877_RS25975
uniprot id: A0A0K2AZT0
names: Similarity
messages: Belongs to the FPG family.

278992:SAM23877 RS17365
gene id: 278992:SAM23877_RS17365
uniprot id: A0A0K2AUP0
names: Subcellular Location Annotation
messages: Cell membrane

278992:SAM23877 RS23390
gene id: 278992:SAM23877_RS23390
uniprot id: A0A0K2AY66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

278992:SAM23877 RS05930
gene id: 278992:SAM23877_RS05930
uniprot id: A3KKF6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

278992:SAM23877 RS26945
gene id: 278992:SAM23877_RS26945
uniprot id: A0A0K2B0U4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

278992:SAM23877 RS13625
gene id: 278992:SAM23877_RS13625
uniprot id: A0A0K2ASX6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

278992:SAM23877 RS05185
gene id: 278992:SAM23877_RS05185
uniprot id: A3KK08
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

278992:SAM23877 RS21235
gene id: 278992:SAM23877_RS21235
uniprot id: A0A0K2AWP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

278992:SAM23877 RS24905
gene id: 278992:SAM23877_RS24905
uniprot id: A0A0K2AZM3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

278992:SAM23877 RS25125
gene id: 278992:SAM23877_RS25125
uniprot id: A0A0K2AZK3
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

278992:SAM23877 RS13470
gene id: 278992:SAM23877_RS13470
uniprot id: A0A0K2ASF2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

278992:SAM23877 RS06625
gene id: 278992:SAM23877_RS06625
uniprot id: A0A0K2ANB4
names: Similarity
messages: Belongs to the UPF0749 family.

278992:SAM23877 RS02950
gene id: 278992:SAM23877_RS02950
uniprot id: A3KIQ8
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS23775
gene id: 278992:SAM23877_RS23775
uniprot id: A0A0K2AYG6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

278992:SAM23877 RS24625
gene id: 278992:SAM23877_RS24625
uniprot id: A0A0K2AZ40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

278992:SAM23877 RS15320
gene id: 278992:SAM23877_RS15320
uniprot id: A0A0K2ATI9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

278992:SAM23877 RS28265
gene id: 278992:SAM23877_RS28265
uniprot id: A0A0K2B1H1
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

278992:SAM23877 RS22440
gene id: 278992:SAM23877_RS22440
uniprot id: A0A0K2AXT6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS12165
gene id: 278992:SAM23877_RS12165
uniprot id: A0A0K2ARL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

278992:SAM23877 RS20785
gene id: 278992:SAM23877_RS20785
uniprot id: A0A0K2AWN4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

278992:SAM23877 RS26125
gene id: 278992:SAM23877_RS26125
uniprot id: A0A0K2AZV7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

278992:SAM23877 RS00630
gene id: 278992:SAM23877_RS00630
uniprot id: Q1RQV2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

278992:SAM23877 RS06810
gene id: 278992:SAM23877_RS06810
uniprot id: A3KKX8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

278992:SAM23877 RS24675
gene id: 278992:SAM23877_RS24675
uniprot id: A0A0K2AZ50
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

278992:SAM23877 RS16390
gene id: 278992:SAM23877_RS16390
uniprot id: A0A0K2AU49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

278992:SAM23877 RS09950
gene id: 278992:SAM23877_RS09950
uniprot id: A0A0K2APY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

278992:SAM23877 RS14840
gene id: 278992:SAM23877_RS14840
uniprot id: A0A0K2AT67
names: Similarity
messages: Belongs to the cytochrome P450 family.

278992:SAM23877 RS19050
gene id: 278992:SAM23877_RS19050
uniprot id: A0A0K2AW77
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS04320
gene id: 278992:SAM23877_RS04320
uniprot id: A3KJI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

278992:SAM23877 RS21335
gene id: 278992:SAM23877_RS21335
uniprot id: A0A0K2AX07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

278992:SAM23877 RS23790
gene id: 278992:SAM23877_RS23790
uniprot id: A0A0K2AZ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

278992:SAM23877 RS25450
gene id: 278992:SAM23877_RS25450
uniprot id: A0A0K2AZL0
names: Similarity
messages: Belongs to the UPF0102 family.

278992:SAM23877 RS17280
gene id: 278992:SAM23877_RS17280
uniprot id: A0A0K2AU82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

278992:SAM23877 RS11215
gene id: 278992:SAM23877_RS11215
uniprot id: A0A0K2AR07
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS01540
gene id: 278992:SAM23877_RS01540
uniprot id: A3KHY4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

278992:SAM23877 RS33140
gene id: 278992:SAM23877_RS33140
uniprot id: A0ACW0
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

278992:SAM23877 RS22835
gene id: 278992:SAM23877_RS22835
uniprot id: A0A0K2AYE8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS19980
gene id: 278992:SAM23877_RS19980
uniprot id: A0A0K2AWI5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS20160
gene id: 278992:SAM23877_RS20160
uniprot id: A0A0K2AWL8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

278992:SAM23877 RS21165
gene id: 278992:SAM23877_RS21165
uniprot id: A0A0K2AWM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

278992:SAM23877 RS21935
gene id: 278992:SAM23877_RS21935
uniprot id: A0A0K2AXH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

278992:SAM23877 RS11130
gene id: 278992:SAM23877_RS11130
uniprot id: A0A0K2AQZ6
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS08780
gene id: 278992:SAM23877_RS08780
uniprot id: A0A0K2APZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

278992:SAM23877 RS19890
gene id: 278992:SAM23877_RS19890
uniprot id: A0A0K2AW81
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS08630
gene id: 278992:SAM23877_RS08630
uniprot id: A0A0K2APQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

278992:SAM23877 RS24550
gene id: 278992:SAM23877_RS24550
uniprot id: A0A0K2AZ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS08895
gene id: 278992:SAM23877_RS08895
uniprot id: A0A0K2APV4
names: Similarity
messages: Belongs to the asp23 family.

278992:SAM23877 RS25640
gene id: 278992:SAM23877_RS25640
uniprot id: A0A0K2AZV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS07255
gene id: 278992:SAM23877_RS07255
uniprot id: A0A0K2AP59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

278992:SAM23877 RS22745
gene id: 278992:SAM23877_RS22745
uniprot id: A0A0K2AXS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

278992:SAM23877 RS30270
gene id: 278992:SAM23877_RS30270
uniprot id: A0A0K2B2I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

278992:SAM23877 RS02670
gene id: 278992:SAM23877_RS02670
uniprot id: A3KIK3
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

278992:SAM23877 RS23715
gene id: 278992:SAM23877_RS23715
uniprot id: A0A0K2AZ02
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

278992:SAM23877 RS20350
gene id: 278992:SAM23877_RS20350
uniprot id: A0A0K2AWY2
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS27565
gene id: 278992:SAM23877_RS27565
uniprot id: A0A0K2B0D2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

278992:SAM23877 RS26470
gene id: 278992:SAM23877_RS26470
uniprot id: A0A0K2B0F1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS19105
gene id: 278992:SAM23877_RS19105
uniprot id: A0A0K2AVS2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

278992:SAM23877 RS29580
gene id: 278992:SAM23877_RS29580
uniprot id: A0A0K2B2F9
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS08160
gene id: 278992:SAM23877_RS08160
uniprot id: A0A0K2AP73
names: Similarity
messages: Belongs to the peptidase S45 family.

278992:SAM23877 RS18200
gene id: 278992:SAM23877_RS18200
uniprot id: A0A0K2AVE9
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

278992:SAM23877 RS09900
gene id: 278992:SAM23877_RS09900
uniprot id: A0A0K2APX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.
messages: Belongs to the glycosyl hydrolase 46 family.
messages: Secreted

278992:SAM23877 RS16680
gene id: 278992:SAM23877_RS16680
uniprot id: A0A0K2AUC5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

278992:SAM23877 RS21615
gene id: 278992:SAM23877_RS21615
uniprot id: A0A0K2AX60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

278992:SAM23877 RS08830
gene id: 278992:SAM23877_RS08830
uniprot id: A0A0K2APK9
names: Similarity
messages: Belongs to the peptidase S8 family.

278992:SAM23877 RS20955
gene id: 278992:SAM23877_RS20955
uniprot id: A0A0K2AWS3
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

278992:SAM23877 RS31160
gene id: 278992:SAM23877_RS31160
uniprot id: A0AE06
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

278992:SAM23877 RS12485
gene id: 278992:SAM23877_RS12485
uniprot id: A0A0K2ARF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

278992:SAM23877 RS33335
gene id: 278992:SAM23877_RS33335
uniprot id: A0ACS2
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

278992:SAM23877 RS10955
gene id: 278992:SAM23877_RS10955
uniprot id: A0A0K2AQV3
names: Similarity
messages: Belongs to the glutamine synthetase family.

278992:SAM23877 RS07460
gene id: 278992:SAM23877_RS07460
uniprot id: A0A0K2ANT0
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

278992:SAM23877 RS06685
gene id: 278992:SAM23877_RS06685
uniprot id: A3KKV3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

278992:SAM23877 RS17230
gene id: 278992:SAM23877_RS17230
uniprot id: A0A0K2AUJ3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

278992:SAM23877 RS27395
gene id: 278992:SAM23877_RS27395
uniprot id: A0A0K2B0Y4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

278992:SAM23877 RS26565
gene id: 278992:SAM23877_RS26565
uniprot id: A0A0K2B0H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 62 family.
messages: Involved in the degradation of xylan and is a key enzyme in the complete degradation of the plant cell wall. It has a specific arabinofuranose-debranching activity on xylan from gramineae. Acts synergistically with the xylanases and binds specifically to xylan. From small arabinoxylo-oligosides (ranging from arabinoxylotriose to arabinoxylohexaose), it liberates arabinose and, after prolonged incubation, the purified enzyme exhibits some xylanolytic activity as well.
messages: Secreted

278992:SAM23877 RS07035
gene id: 278992:SAM23877_RS07035
uniprot id: A0A0K2AP15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

278992:SAM23877 RS11700
gene id: 278992:SAM23877_RS11700
uniprot id: A0A0K2AR09
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

278992:SAM23877 RS24630
gene id: 278992:SAM23877_RS24630
uniprot id: A0A0K2AYY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

278992:SAM23877 RS15140
gene id: 278992:SAM23877_RS15140
uniprot id: A0A0K2ATV9
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

278992:SAM23877 RS02645
gene id: 278992:SAM23877_RS02645
uniprot id: A3KIJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS07070
gene id: 278992:SAM23877_RS07070
uniprot id: A0A0K2ANL2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS06850
gene id: 278992:SAM23877_RS06850
uniprot id: A3KKY6
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

278992:SAM23877 RS07605
gene id: 278992:SAM23877_RS07605
uniprot id: A0A0K2ANV9
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

278992:SAM23877 RS14165
gene id: 278992:SAM23877_RS14165
uniprot id: A0A0K2ASG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

278992:SAM23877 RS22855
gene id: 278992:SAM23877_RS22855
uniprot id: A0A0K2AY75
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS21855
gene id: 278992:SAM23877_RS21855
uniprot id: A0A0K2AXV7
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS12275
gene id: 278992:SAM23877_RS12275
uniprot id: A0A0K2AS67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

278992:SAM23877 RS14255
gene id: 278992:SAM23877_RS14255
uniprot id: A0A0K2AT23
names: Similarity
messages: Belongs to the OsmC/Ohr family.

278992:SAM23877 RS13715
gene id: 278992:SAM23877_RS13715
uniprot id: A0A0K2AS53
names: Similarity
messages: Belongs to the AHA1 family.

278992:SAM23877 RS06125
gene id: 278992:SAM23877_RS06125
uniprot id: A3KKJ5
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

278992:SAM23877 RS13180
gene id: 278992:SAM23877_RS13180
uniprot id: A0A0K2AS69
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS07135
gene id: 278992:SAM23877_RS07135
uniprot id: A0A0K2AP35
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

278992:SAM23877 RS14830
gene id: 278992:SAM23877_RS14830
uniprot id: A0A0K2ATD8
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

278992:SAM23877 RS07050
gene id: 278992:SAM23877_RS07050
uniprot id: A0A0K2ANC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

278992:SAM23877 RS08420
gene id: 278992:SAM23877_RS08420
uniprot id: A0A0K2APC7
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS06320
gene id: 278992:SAM23877_RS06320
uniprot id: A3KKN3
names: Similarity
messages: Belongs to the IMPACT family.

278992:SAM23877 RS07960
gene id: 278992:SAM23877_RS07960
uniprot id: A0A0K2APC0
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

278992:SAM23877 RS04295
gene id: 278992:SAM23877_RS04295
uniprot id: A3KJH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

278992:SAM23877 RS24655
gene id: 278992:SAM23877_RS24655
uniprot id: A0A0K2AYZ0
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

278992:SAM23877 RS06015
gene id: 278992:SAM23877_RS06015
uniprot id: A3KKH3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

278992:SAM23877 RS23130
gene id: 278992:SAM23877_RS23130
uniprot id: A0A0K2AY79
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS15325
gene id: 278992:SAM23877_RS15325
uniprot id: A0A0K2AT48
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

278992:SAM23877 RS18870
gene id: 278992:SAM23877_RS18870
uniprot id: A0A0K2AVM4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS26415
gene id: 278992:SAM23877_RS26415
uniprot id: A0A0K2B066
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS13270
gene id: 278992:SAM23877_RS13270
uniprot id: A0A0K2ASR0
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

278992:SAM23877 RS24980
gene id: 278992:SAM23877_RS24980
uniprot id: A0A0K2AZB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

278992:SAM23877 RS02355
gene id: 278992:SAM23877_RS02355
uniprot id: A3KIE4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

278992:SAM23877 RS22075
gene id: 278992:SAM23877_RS22075
uniprot id: A0A0K2AXK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Belongs to the peptidase S8 family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS22350
gene id: 278992:SAM23877_RS22350
uniprot id: A0A0K2AXJ6
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS09895
gene id: 278992:SAM23877_RS09895
uniprot id: A0A0K2AQA0
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS07105
gene id: 278992:SAM23877_RS07105
uniprot id: A0A0K2ANV1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

278992:SAM23877 RS21375
gene id: 278992:SAM23877_RS21375
uniprot id: A0A0K2AXL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

278992:SAM23877 RS02105
gene id: 278992:SAM23877_RS02105
uniprot id: A3KI94
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

278992:SAM23877 RS02975
gene id: 278992:SAM23877_RS02975
uniprot id: A0A0K2ALL1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS25410
gene id: 278992:SAM23877_RS25410
uniprot id: A0A0K2AZ36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

278992:SAM23877 RS03595
gene id: 278992:SAM23877_RS03595
uniprot id: A3KJ38
names: Similarity
messages: Belongs to the peptidase S1 family.

278992:SAM23877 RS26185
gene id: 278992:SAM23877_RS26185
uniprot id: A0A0K2B090
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

278992:SAM23877 RS04045
gene id: 278992:SAM23877_RS04045
uniprot id: A3KJC7
names: Similarity
messages: Belongs to the universal stress protein A family.

278992:SAM23877 RS00775
gene id: 278992:SAM23877_RS00775
uniprot id: Q1RQS3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

278992:SAM23877 RS24085
gene id: 278992:SAM23877_RS24085
uniprot id: A0A0K2AYT7
names: Subcellular Location Annotation
messages: Cell membrane

278992:SAM23877 RS10475
gene id: 278992:SAM23877_RS10475
uniprot id: A0A0K2AR31
names: Similarity
messages: Belongs to the peptidase C40 family.

278992:SAM23877 RS14435
gene id: 278992:SAM23877_RS14435
uniprot id: A0A0K2ASY5
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS21365
gene id: 278992:SAM23877_RS21365
uniprot id: A0A0K2AWR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

278992:SAM23877 RS19005
gene id: 278992:SAM23877_RS19005
uniprot id: A0A0K2AVX9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

278992:SAM23877 RS13920
gene id: 278992:SAM23877_RS13920
uniprot id: A0A0K2AS99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

278992:SAM23877 RS02365
gene id: 278992:SAM23877_RS02365
uniprot id: A3KIE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

278992:SAM23877 RS12005
gene id: 278992:SAM23877_RS12005
uniprot id: A0A0K2AS15
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS21965
gene id: 278992:SAM23877_RS21965
uniprot id: A0A0K2AX17
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

278992:SAM23877 RS13360
gene id: 278992:SAM23877_RS13360
uniprot id: A0A0K2ASI0
names: Subcellular Location Annotation
messages: Cell membrane

278992:SAM23877 RS36415
gene id: 278992:SAM23877_RS36415
uniprot id: A0A0K2B5T3
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

278992:SAM23877 RS10470
gene id: 278992:SAM23877_RS10470
uniprot id: A0A0K2AQU3
names: Similarity
messages: Belongs to the peptidase C40 family.

278992:SAM23877 RS19470
gene id: 278992:SAM23877_RS19470
uniprot id: A0A0K2AWG6
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS30165
gene id: 278992:SAM23877_RS30165
uniprot id: A0A0K2B2M3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

278992:SAM23877 RS30665
gene id: 278992:SAM23877_RS30665
uniprot id: A0AEA3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

278992:SAM23877 RS10200
gene id: 278992:SAM23877_RS10200
uniprot id: A0A0K2AQG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS28640
gene id: 278992:SAM23877_RS28640
uniprot id: A0A0K2B1R2
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

278992:SAM23877 RS07060
gene id: 278992:SAM23877_RS07060
uniprot id: A0A0K2AP20
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

278992:SAM23877 RS30590
gene id: 278992:SAM23877_RS30590
uniprot id: A0AEB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS35065
gene id: 278992:SAM23877_RS35065
uniprot id: Q1RQK5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS25760
gene id: 278992:SAM23877_RS25760
uniprot id: A0A0K2AZB3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

278992:SAM23877 RS26705
gene id: 278992:SAM23877_RS26705
uniprot id: A0A0K2B063
names: Similarity
messages: Belongs to the thioesterase family.

278992:SAM23877 RS07300
gene id: 278992:SAM23877_RS07300
uniprot id: A0A0K2ANZ0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS27685
gene id: 278992:SAM23877_RS27685
uniprot id: A0A0K2B0G1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

278992:SAM23877 RS25205
gene id: 278992:SAM23877_RS25205
uniprot id: A0A0K2AZA4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

278992:SAM23877 RS07190
gene id: 278992:SAM23877_RS07190
uniprot id: A0A0K2ANN2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

278992:SAM23877 RS13060
gene id: 278992:SAM23877_RS13060
uniprot id: A0A0K2AS48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

278992:SAM23877 RS12055
gene id: 278992:SAM23877_RS12055
uniprot id: A0A0K2ARI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

278992:SAM23877 RS25215
gene id: 278992:SAM23877_RS25215
uniprot id: A0A0K2AZL9
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

278992:SAM23877 RS05095
gene id: 278992:SAM23877_RS05095
uniprot id: A3KJY9
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

278992:SAM23877 RS02735
gene id: 278992:SAM23877_RS02735
uniprot id: A3KIL5
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

278992:SAM23877 RS25630
gene id: 278992:SAM23877_RS25630
uniprot id: A0A0K2AZI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

278992:SAM23877 RS34265
gene id: 278992:SAM23877_RS34265
uniprot id: A0AC90
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

278992:SAM23877 RS25955
gene id: 278992:SAM23877_RS25955
uniprot id: A0A0K2AZH5
names: Similarity
messages: Belongs to the Dps family.

278992:SAM23877 RS25045
gene id: 278992:SAM23877_RS25045
uniprot id: A0A0K2AZD2
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

278992:SAM23877 RS31670
gene id: 278992:SAM23877_RS31670
uniprot id: A0ADQ4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

278992:SAM23877 RS09915
gene id: 278992:SAM23877_RS09915
uniprot id: A0A0K2AQ85
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS10755
gene id: 278992:SAM23877_RS10755
uniprot id: A0A0K2AR86
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

278992:SAM23877 RS06210
gene id: 278992:SAM23877_RS06210
uniprot id: A3KKL1
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

278992:SAM23877 RS06090
gene id: 278992:SAM23877_RS06090
uniprot id: A3KKI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS32175
gene id: 278992:SAM23877_RS32175
uniprot id: A0ADF4
names: Similarity
messages: Belongs to the peptidase S1 family.

278992:SAM23877 RS12400
gene id: 278992:SAM23877_RS12400
uniprot id: A0A0K2ARZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

278992:SAM23877 RS22545
gene id: 278992:SAM23877_RS22545
uniprot id: A0A0K2AY10
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

278992:SAM23877 RS11645
gene id: 278992:SAM23877_RS11645
uniprot id: A0A0K2ARB5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

278992:SAM23877 RS26405
gene id: 278992:SAM23877_RS26405
uniprot id: A0A0K2B0D6
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

278992:SAM23877 RS13300
gene id: 278992:SAM23877_RS13300
uniprot id: A0A0K2ASB8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

278992:SAM23877 RS24570
gene id: 278992:SAM23877_RS24570
uniprot id: A0A0K2AZG2
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS19015
gene id: 278992:SAM23877_RS19015
uniprot id: A0A0K2AVL7
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

278992:SAM23877 RS29895
gene id: 278992:SAM23877_RS29895
uniprot id: A0A0K2B1S9
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS28625
gene id: 278992:SAM23877_RS28625
uniprot id: A0A0K2B1J8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

278992:SAM23877 RS23825
gene id: 278992:SAM23877_RS23825
uniprot id: A0A0K2AYH5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS14655
gene id: 278992:SAM23877_RS14655
uniprot id: A0A0K2ASQ8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

278992:SAM23877 RS10125
gene id: 278992:SAM23877_RS10125
uniprot id: A0A0K2AQE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

278992:SAM23877 RS20790
gene id: 278992:SAM23877_RS20790
uniprot id: A0A0K2AWC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

278992:SAM23877 RS31505
gene id: 278992:SAM23877_RS31505
uniprot id: A0ADT7
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

278992:SAM23877 RS13700
gene id: 278992:SAM23877_RS13700
uniprot id: A0A0K2ASZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

278992:SAM23877 RS25735
gene id: 278992:SAM23877_RS25735
uniprot id: A0A0K2AZA8
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS15005
gene id: 278992:SAM23877_RS15005
uniprot id: A0A0K2ATA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

278992:SAM23877 RS11065
gene id: 278992:SAM23877_RS11065
uniprot id: A0A0K2AQL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

278992:SAM23877 RS09170
gene id: 278992:SAM23877_RS09170
uniprot id: A0A0K2APV1
names: Similarity
messages: Belongs to the DapA family.

278992:SAM23877 RS19825
gene id: 278992:SAM23877_RS19825
uniprot id: A0A0K2AWM6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS22535
gene id: 278992:SAM23877_RS22535
uniprot id: A0A0K2AXN4
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

278992:SAM23877 RS33040
gene id: 278992:SAM23877_RS33040
uniprot id: A0ACX9
names: Similarity
messages: Belongs to the Fur family.

278992:SAM23877 RS25835
gene id: 278992:SAM23877_RS25835
uniprot id: A0A0K2AZT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

278992:SAM23877 RS16080
gene id: 278992:SAM23877_RS16080
uniprot id: A0A0K2ATZ7
names: Subcellular Location Annotation
messages: Cytoplasm

278992:SAM23877 RS08720
gene id: 278992:SAM23877_RS08720
uniprot id: A0A0K2APK8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

278992:SAM23877 RS30535
gene id: 278992:SAM23877_RS30535
uniprot id: A0A0K2B2H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

278992:SAM23877 RS09450
gene id: 278992:SAM23877_RS09450
uniprot id: A0A0K2AQ22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

278992:SAM23877 RS21175
gene id: 278992:SAM23877_RS21175
uniprot id: A0A0K2AXH4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

278992:SAM23877 RS22930
gene id: 278992:SAM23877_RS22930
uniprot id: A0A0K2AY36
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

278992:SAM23877 RS14835
gene id: 278992:SAM23877_RS14835
uniprot id: A0A0K2AT97
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

278992:SAM23877 RS15670
gene id: 278992:SAM23877_RS15670
uniprot id: A0A0K2ATR1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS24205
gene id: 278992:SAM23877_RS24205
uniprot id: A0A0K2AZ15
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS16015
gene id: 278992:SAM23877_RS16015
uniprot id: A0A0K2ATJ3
names: Similarity
messages: Belongs to the CutC family.

278992:SAM23877 RS12440
gene id: 278992:SAM23877_RS12440
uniprot id: A0A0K2ARS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

278992:SAM23877 RS13990
gene id: 278992:SAM23877_RS13990
uniprot id: A0A0K2ASQ1
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

278992:SAM23877 RS04500
gene id: 278992:SAM23877_RS04500
uniprot id: A3KJL8
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS31855
gene id: 278992:SAM23877_RS31855
uniprot id: A0ADL8
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS21540
gene id: 278992:SAM23877_RS21540
uniprot id: A0A0K2AWU4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

278992:SAM23877 RS21155
gene id: 278992:SAM23877_RS21155
uniprot id: A0A0K2AWX8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

278992:SAM23877 RS33280
gene id: 278992:SAM23877_RS33280
uniprot id: A0ACT3
names: Subcellular Location Annotation
messages: Cytoplasm

278992:SAM23877 RS11595
gene id: 278992:SAM23877_RS11595
uniprot id: A0A0K2ARA4
names: Similarity
messages: Belongs to the aldose epimerase family.

278992:SAM23877 RS17755
gene id: 278992:SAM23877_RS17755
uniprot id: A0A0K2AUU8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

278992:SAM23877 RS23205
gene id: 278992:SAM23877_RS23205
uniprot id: A0A0K2AY23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

278992:SAM23877 RS24705
gene id: 278992:SAM23877_RS24705
uniprot id: A0A0K2AYZ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

278992:SAM23877 RS22985
gene id: 278992:SAM23877_RS22985
uniprot id: A0A0K2AXX9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

278992:SAM23877 RS13555
gene id: 278992:SAM23877_RS13555
uniprot id: A0A0K2AS22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS08965
gene id: 278992:SAM23877_RS08965
uniprot id: A0A0K2APW9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

278992:SAM23877 RS24425
gene id: 278992:SAM23877_RS24425
uniprot id: A0A0K2AZD5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

278992:SAM23877 RS32845
gene id: 278992:SAM23877_RS32845
uniprot id: A0A0K2B4F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

278992:SAM23877 RS35430
gene id: 278992:SAM23877_RS35430
uniprot id: Q1RQT3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

278992:SAM23877 RS34445
gene id: 278992:SAM23877_RS34445
uniprot id: A0AC55
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

278992:SAM23877 RS30930
gene id: 278992:SAM23877_RS30930
uniprot id: A0A0K2B2H8
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS07555
gene id: 278992:SAM23877_RS07555
uniprot id: A0A0K2APB1
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS07230
gene id: 278992:SAM23877_RS07230
uniprot id: A0A0K2AP55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

278992:SAM23877 RS31685
gene id: 278992:SAM23877_RS31685
uniprot id: A0ADQ1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS26970
gene id: 278992:SAM23877_RS26970
uniprot id: A0A0K2B0H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

278992:SAM23877 RS29760
gene id: 278992:SAM23877_RS29760
uniprot id: A0A0K2B213
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

278992:SAM23877 RS16075
gene id: 278992:SAM23877_RS16075
uniprot id: A0A0K2AUF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

278992:SAM23877 RS05895
gene id: 278992:SAM23877_RS05895
uniprot id: A3KKE8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS23640
gene id: 278992:SAM23877_RS23640
uniprot id: A0A0K2AYY7
names: Similarity
messages: Belongs to the peptidase S16 family.

278992:SAM23877 RS21620
gene id: 278992:SAM23877_RS21620
uniprot id: A0A0K2AWW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

278992:SAM23877 RS15760
gene id: 278992:SAM23877_RS15760
uniprot id: A0A0K2AU02
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

278992:SAM23877 RS12170
gene id: 278992:SAM23877_RS12170
uniprot id: A0A0K2ARL4
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS13890
gene id: 278992:SAM23877_RS13890
uniprot id: A0A0K2ASN9
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS04590
gene id: 278992:SAM23877_RS04590
uniprot id: A3KJN6
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

278992:SAM23877 RS33645
gene id: 278992:SAM23877_RS33645
uniprot id: A0ACL2
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

278992:SAM23877 RS06115
gene id: 278992:SAM23877_RS06115
uniprot id: A3KKJ3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS03580
gene id: 278992:SAM23877_RS03580
uniprot id: A3KJ35
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

278992:SAM23877 RS18505
gene id: 278992:SAM23877_RS18505
uniprot id: A0A0K2AVT8
names: Subcellular Location Annotation
messages: Cytoplasm

278992:SAM23877 RS31015
gene id: 278992:SAM23877_RS31015
uniprot id: A0AE35
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

278992:SAM23877 RS07815
gene id: 278992:SAM23877_RS07815
uniprot id: A0A0K2AP91
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

278992:SAM23877 RS02770
gene id: 278992:SAM23877_RS02770
uniprot id: A3KIM2
names: Function
names: Subcellular Location Annotation
messages: Involved in chitin degradation. Catalyzes the oxidative cleavage of glycosidic bonds in chitin via a copper-dependent mechanism, leading to oxidized chitooligomers with degrees of polymerization of 4-6. Is not active on cellulose.
messages: Secreted

278992:SAM23877 RS02180
gene id: 278992:SAM23877_RS02180
uniprot id: A3KIA9
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

278992:SAM23877 RS04840
gene id: 278992:SAM23877_RS04840
uniprot id: A3KJT8
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

278992:SAM23877 RS23030
gene id: 278992:SAM23877_RS23030
uniprot id: A0A0K2AY58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

278992:SAM23877 RS03575
gene id: 278992:SAM23877_RS03575
uniprot id: A3KJ34
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

278992:SAM23877 RS06910
gene id: 278992:SAM23877_RS06910
uniprot id: A3KKZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

278992:SAM23877 RS29450
gene id: 278992:SAM23877_RS29450
uniprot id: A0A0K2B1J4
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

278992:SAM23877 RS32630
gene id: 278992:SAM23877_RS32630
uniprot id: A0AD61
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

278992:SAM23877 RS22575
gene id: 278992:SAM23877_RS22575
uniprot id: A0A0K2AXE0
names: Similarity
messages: Belongs to the peptidase S8 family.

278992:SAM23877 RS20810
gene id: 278992:SAM23877_RS20810
uniprot id: A0A0K2AWN9
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS10170
gene id: 278992:SAM23877_RS10170
uniprot id: A0A0K2AQD7
names: Similarity
messages: Belongs to the YggT family.

278992:SAM23877 RS20805
gene id: 278992:SAM23877_RS20805
uniprot id: A0A0K2AWS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

278992:SAM23877 RS00870
gene id: 278992:SAM23877_RS00870
uniprot id: Q1RQQ4
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

278992:SAM23877 RS29790
gene id: 278992:SAM23877_RS29790
uniprot id: A0A0K2B1Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

278992:SAM23877 RS01695
gene id: 278992:SAM23877_RS01695
uniprot id: A3KI17
names: Function
names: Miscellaneous
names: Similarity
messages: 2-MIB is a volatile organic compound that has an unusually low odor threshold. Together with geosmin, methylisoborneol is responsible for the characteristic smell of moist soil as well as unpleasant taste and odor episodes associated with public water supplies and contamination of various foodstuffs, including fish, wine, and beer.
messages: Belongs to the terpene synthase family. 2-methylisoborneol synthase subfamily.
messages: Catalyzes the cyclization of 2-methylgeranyl diphosphate (2-MeGPP) to 2-methylisoborneol (2-MIB), which likely involves the intermediacy of 2-methyllinalyl diphosphate.

278992:SAM23877 RS23345
gene id: 278992:SAM23877_RS23345
uniprot id: A0A0K2AY56
names: Similarity
messages: Belongs to the LOG family.

278992:SAM23877 RS25195
gene id: 278992:SAM23877_RS25195
uniprot id: A0A0K2AZL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

278992:SAM23877 RS29595
gene id: 278992:SAM23877_RS29595
uniprot id: A0A0K2B1M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS25050
gene id: 278992:SAM23877_RS25050
uniprot id: A0A0K2AZ77
names: Similarity
messages: Belongs to the agmatine deiminase family.

278992:SAM23877 RS04720
gene id: 278992:SAM23877_RS04720
uniprot id: A3KJR2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

278992:SAM23877 RS05690
gene id: 278992:SAM23877_RS05690
uniprot id: A3KKA7
names: Similarity
messages: Belongs to the tannase family.

278992:SAM23877 RS05750
gene id: 278992:SAM23877_RS05750
uniprot id: A0A0K2AMT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

278992:SAM23877 RS18855
gene id: 278992:SAM23877_RS18855
uniprot id: A0A0K2AV77
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS09015
gene id: 278992:SAM23877_RS09015
uniprot id: A0A0K2APY1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

278992:SAM23877 RS24470
gene id: 278992:SAM23877_RS24470
uniprot id: A0A0K2AZE4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS19740
gene id: 278992:SAM23877_RS19740
uniprot id: A0A0K2AVP8
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

278992:SAM23877 RS21885
gene id: 278992:SAM23877_RS21885
uniprot id: A0A0K2AXG8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

278992:SAM23877 RS27470
gene id: 278992:SAM23877_RS27470
uniprot id: A0A0K2B0Z9
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

278992:SAM23877 RS26140
gene id: 278992:SAM23877_RS26140
uniprot id: A0A0K2B0D5
names: Similarity
messages: Belongs to the RelA/SpoT family.

278992:SAM23877 RS23930
gene id: 278992:SAM23877_RS23930
uniprot id: A0A0K2AZ42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS22155
gene id: 278992:SAM23877_RS22155
uniprot id: A0A0K2AXF8
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS24045
gene id: 278992:SAM23877_RS24045
uniprot id: A0A0K2AYB3
names: Similarity
messages: Belongs to the peptidase C40 family.

278992:SAM23877 RS04995
gene id: 278992:SAM23877_RS04995
uniprot id: A3KJW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS21815
gene id: 278992:SAM23877_RS21815
uniprot id: A0A0K2AX92
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

278992:SAM23877 RS09350
gene id: 278992:SAM23877_RS09350
uniprot id: A0A0K2AQ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS29995
gene id: 278992:SAM23877_RS29995
uniprot id: A0A0K2B2I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

278992:SAM23877 RS21350
gene id: 278992:SAM23877_RS21350
uniprot id: A0A0K2AXK8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

278992:SAM23877 RS09780
gene id: 278992:SAM23877_RS09780
uniprot id: A0A0K2AQE5
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

278992:SAM23877 RS06950
gene id: 278992:SAM23877_RS06950
uniprot id: A0A0K2ANA3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS25040
gene id: 278992:SAM23877_RS25040
uniprot id: A0A0K2AZQ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits.
messages: In the C-terminal section; belongs to the urease beta subunit family.
messages: In the N-terminal section; belongs to the urease gamma subunit family.

278992:SAM23877 RS11865
gene id: 278992:SAM23877_RS11865
uniprot id: A0A0K2ARY7
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS26260
gene id: 278992:SAM23877_RS26260
uniprot id: A0A0K2B037
names: Similarity
messages: Belongs to the Nudix hydrolase family.

278992:SAM23877 RS10310
gene id: 278992:SAM23877_RS10310
uniprot id: A0A0K2AQQ7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS05485
gene id: 278992:SAM23877_RS05485
uniprot id: A3KK66
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

278992:SAM23877 RS26305
gene id: 278992:SAM23877_RS26305
uniprot id: A0A0K2AZY7
names: Subcellular Location Annotation
messages: Cytoplasm

278992:SAM23877 RS25935
gene id: 278992:SAM23877_RS25935
uniprot id: A0A0K2B023
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

278992:SAM23877 RS12805
gene id: 278992:SAM23877_RS12805
uniprot id: A0A0K2ARL3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

278992:SAM23877 RS32840
gene id: 278992:SAM23877_RS32840
uniprot id: A0AD20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

278992:SAM23877 RS33560
gene id: 278992:SAM23877_RS33560
uniprot id: A0ACM7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

278992:SAM23877 RS32770
gene id: 278992:SAM23877_RS32770
uniprot id: A0AD34
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

278992:SAM23877 RS06700
gene id: 278992:SAM23877_RS06700
uniprot id: A3KKV6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS09120
gene id: 278992:SAM23877_RS09120
uniprot id: A0A0K2APS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

278992:SAM23877 RS21280
gene id: 278992:SAM23877_RS21280
uniprot id: A0A0K2AX39
names: Similarity
messages: Belongs to the peptidase S1 family.

278992:SAM23877 RS25605
gene id: 278992:SAM23877_RS25605
uniprot id: A0A0K2AZI1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

278992:SAM23877 RS32820
gene id: 278992:SAM23877_RS32820
uniprot id: A0A0K2B491
names: Similarity
messages: Belongs to the XFP family.

278992:SAM23877 RS04700
gene id: 278992:SAM23877_RS04700
uniprot id: A3KJQ8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

278992:SAM23877 RS34685
gene id: 278992:SAM23877_RS34685
uniprot id: A0AC09
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

278992:SAM23877 RS16915
gene id: 278992:SAM23877_RS16915
uniprot id: A0A0K2AUP8
names: Function
names: Similarity
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

278992:SAM23877 RS09960
gene id: 278992:SAM23877_RS09960
uniprot id: A0A0K2AQQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

278992:SAM23877 RS33705
gene id: 278992:SAM23877_RS33705
uniprot id: A0ACJ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

278992:SAM23877 RS15570
gene id: 278992:SAM23877_RS15570
uniprot id: A0A0K2ATV8
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

278992:SAM23877 RS00635
gene id: 278992:SAM23877_RS00635
uniprot id: A0A0K2AJL7
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

278992:SAM23877 RS09475
gene id: 278992:SAM23877_RS09475
uniprot id: A0A0K2AQ25
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

278992:SAM23877 RS08775
gene id: 278992:SAM23877_RS08775
uniprot id: A0A0K2APT3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

278992:SAM23877 RS06560
gene id: 278992:SAM23877_RS06560
uniprot id: A3KKT2
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

278992:SAM23877 RS09435
gene id: 278992:SAM23877_RS09435
uniprot id: A0A0K2AQ83
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS30735
gene id: 278992:SAM23877_RS30735
uniprot id: A0AE93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

278992:SAM23877 RS25030
gene id: 278992:SAM23877_RS25030
uniprot id: A0A0K2AZ71
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

278992:SAM23877 RS26675
gene id: 278992:SAM23877_RS26675
uniprot id: A0A0K2B0B8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

278992:SAM23877 RS06940
gene id: 278992:SAM23877_RS06940
uniprot id: A0A0K2ANJ5
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS20185
gene id: 278992:SAM23877_RS20185
uniprot id: A0A0K2AWM2
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

278992:SAM23877 RS00665
gene id: 278992:SAM23877_RS00665
uniprot id: Q1RQU5
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS36480
gene id: 278992:SAM23877_RS36480
uniprot id: A0A0K2B6B4
names: Similarity
messages: Belongs to the ParB family.

278992:SAM23877 RS21465
gene id: 278992:SAM23877_RS21465
uniprot id: A0A0K2AX28
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

278992:SAM23877 RS05355
gene id: 278992:SAM23877_RS05355
uniprot id: A3KK40
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

278992:SAM23877 RS34180
gene id: 278992:SAM23877_RS34180
uniprot id: A0ACA6
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

278992:SAM23877 RS03015
gene id: 278992:SAM23877_RS03015
uniprot id: A3KIS1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

278992:SAM23877 RS25455
gene id: 278992:SAM23877_RS25455
uniprot id: A0A0K2AZF5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

278992:SAM23877 RS12975
gene id: 278992:SAM23877_RS12975
uniprot id: A0A0K2AS29
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS06250
gene id: 278992:SAM23877_RS06250
uniprot id: A3KKL9
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS09340
gene id: 278992:SAM23877_RS09340
uniprot id: A0A0K2AQE1
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

278992:SAM23877 RS07845
gene id: 278992:SAM23877_RS07845
uniprot id: A0A0K2APH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

278992:SAM23877 RS03865
gene id: 278992:SAM23877_RS03865
uniprot id: A3KJ92
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

278992:SAM23877 RS17100
gene id: 278992:SAM23877_RS17100
uniprot id: A0A0K2AUJ1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

278992:SAM23877 RS18035
gene id: 278992:SAM23877_RS18035
uniprot id: A0A0K2AV35
names: Similarity
messages: Belongs to the UPF0749 family.

278992:SAM23877 RS22815
gene id: 278992:SAM23877_RS22815
uniprot id: A0A0K2AY12
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS13395
gene id: 278992:SAM23877_RS13395
uniprot id: A0A0K2ASD7
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS28650
gene id: 278992:SAM23877_RS28650
uniprot id: A0A0K2B1K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

278992:SAM23877 RS14505
gene id: 278992:SAM23877_RS14505
uniprot id: A0A0K2AT70
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

278992:SAM23877 RS20305
gene id: 278992:SAM23877_RS20305
uniprot id: A0A0K2AWX2
names: Similarity
messages: Belongs to the asp23 family.

278992:SAM23877 RS17350
gene id: 278992:SAM23877_RS17350
uniprot id: A0A0K2AU96
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS04445
gene id: 278992:SAM23877_RS04445
uniprot id: A3KJK7
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS21230
gene id: 278992:SAM23877_RS21230
uniprot id: A0A0K2AWZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

278992:SAM23877 RS16100
gene id: 278992:SAM23877_RS16100
uniprot id: A0A0K2AUF5
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

278992:SAM23877 RS10690
gene id: 278992:SAM23877_RS10690
uniprot id: A0A0K2AQP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

278992:SAM23877 RS21020
gene id: 278992:SAM23877_RS21020
uniprot id: A0A0K2AXC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

278992:SAM23877 RS06485
gene id: 278992:SAM23877_RS06485
uniprot id: A3KKR7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS08375
gene id: 278992:SAM23877_RS08375
uniprot id: A0A0K2APS2
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

278992:SAM23877 RS03725
gene id: 278992:SAM23877_RS03725
uniprot id: A3KJ65
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

278992:SAM23877 RS12230
gene id: 278992:SAM23877_RS12230
uniprot id: A0A0K2ARV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

278992:SAM23877 RS16165
gene id: 278992:SAM23877_RS16165
uniprot id: A0A0K2AU88
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

278992:SAM23877 RS02835
gene id: 278992:SAM23877_RS02835
uniprot id: A3KIN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS24710
gene id: 278992:SAM23877_RS24710
uniprot id: A0A0K2AYN7
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS13130
gene id: 278992:SAM23877_RS13130
uniprot id: A0A0K2AS88
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS05120
gene id: 278992:SAM23877_RS05120
uniprot id: A3KJZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

278992:SAM23877 RS09285
gene id: 278992:SAM23877_RS09285
uniprot id: A0A0K2AQ55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

278992:SAM23877 RS09525
gene id: 278992:SAM23877_RS09525
uniprot id: A0A0K2AQ35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

278992:SAM23877 RS18020
gene id: 278992:SAM23877_RS18020
uniprot id: A0A0K2AUM8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

278992:SAM23877 RS20710
gene id: 278992:SAM23877_RS20710
uniprot id: A0A0K2AX62
names: Similarity
messages: Belongs to the peptidase A24 family.

278992:SAM23877 RS07250
gene id: 278992:SAM23877_RS07250
uniprot id: A0A0K2ANY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

278992:SAM23877 RS18490
gene id: 278992:SAM23877_RS18490
uniprot id: A0A0K2AV93
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS35545
gene id: 278992:SAM23877_RS35545
uniprot id: Q1RQV6
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

278992:SAM23877 RS16090
gene id: 278992:SAM23877_RS16090
uniprot id: A0A0K2ATK8
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

278992:SAM23877 RS34185
gene id: 278992:SAM23877_RS34185
uniprot id: A0ACA5
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

278992:SAM23877 RS25295
gene id: 278992:SAM23877_RS25295
uniprot id: A0A0K2AZN6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

278992:SAM23877 RS13015
gene id: 278992:SAM23877_RS13015
uniprot id: A0A0K2AS40
names: Similarity
messages: Belongs to the citrate synthase family.

278992:SAM23877 RS16735
gene id: 278992:SAM23877_RS16735
uniprot id: A0A0K2AUA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

278992:SAM23877 RS17360
gene id: 278992:SAM23877_RS17360
uniprot id: A0A0K2AV61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

278992:SAM23877 RS12370
gene id: 278992:SAM23877_RS12370
uniprot id: A0A0K2ARQ6
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

278992:SAM23877 RS24525
gene id: 278992:SAM23877_RS24525
uniprot id: A0A0K2AZ20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

278992:SAM23877 RS28075
gene id: 278992:SAM23877_RS28075
uniprot id: A0A0K2B167
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GmhB family.
messages: Cytoplasm

278992:SAM23877 RS20290
gene id: 278992:SAM23877_RS20290
uniprot id: A0A0K2AWD0
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS04750
gene id: 278992:SAM23877_RS04750
uniprot id: A3KJR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS35700
gene id: 278992:SAM23877_RS35700
uniprot id: Q1RQY8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

278992:SAM23877 RS05790
gene id: 278992:SAM23877_RS05790
uniprot id: A3KKC6
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS25435
gene id: 278992:SAM23877_RS25435
uniprot id: A0A0K2AZ43
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

278992:SAM23877 RS27290
gene id: 278992:SAM23877_RS27290
uniprot id: A0A0K2B080
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

278992:SAM23877 RS08795
gene id: 278992:SAM23877_RS08795
uniprot id: A0A0K2AP98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

278992:SAM23877 RS25590
gene id: 278992:SAM23877_RS25590
uniprot id: A0A0K2AZU8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

278992:SAM23877 RS22080
gene id: 278992:SAM23877_RS22080
uniprot id: A0A0K2AXE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS06675
gene id: 278992:SAM23877_RS06675
uniprot id: A3KKV1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

278992:SAM23877 RS03635
gene id: 278992:SAM23877_RS03635
uniprot id: A3KJ46
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

278992:SAM23877 RS22240
gene id: 278992:SAM23877_RS22240
uniprot id: A0A0K2AY29
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

278992:SAM23877 RS15725
gene id: 278992:SAM23877_RS15725
uniprot id: A0A0K2ATQ0
names: Similarity
messages: Belongs to the UPF0309 family.

278992:SAM23877 RS19450
gene id: 278992:SAM23877_RS19450
uniprot id: A0A0K2AW73
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

278992:SAM23877 RS02825
gene id: 278992:SAM23877_RS02825
uniprot id: A3KIN3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

278992:SAM23877 RS18030
gene id: 278992:SAM23877_RS18030
uniprot id: A0A0K2AVJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

278992:SAM23877 RS18865
gene id: 278992:SAM23877_RS18865
uniprot id: A0A0K2AW37
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS07905
gene id: 278992:SAM23877_RS07905
uniprot id: A0A0K2ANR9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

278992:SAM23877 RS13350
gene id: 278992:SAM23877_RS13350
uniprot id: A0A0K2ASA3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

278992:SAM23877 RS09715
gene id: 278992:SAM23877_RS09715
uniprot id: A0A0K2AQ46
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS27650
gene id: 278992:SAM23877_RS27650
uniprot id: A0A0K2B0X0
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS01305
gene id: 278992:SAM23877_RS01305
uniprot id: A3KHT5
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

278992:SAM23877 RS21570
gene id: 278992:SAM23877_RS21570
uniprot id: A0A0K2AXQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

278992:SAM23877 RS01310
gene id: 278992:SAM23877_RS01310
uniprot id: A3KHT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS36545
gene id: 278992:SAM23877_RS36545
uniprot id: A0A0K2B6E2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

278992:SAM23877 RS24760
gene id: 278992:SAM23877_RS24760
uniprot id: A0A0K2AYP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS05280
gene id: 278992:SAM23877_RS05280
uniprot id: A3KK26
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

278992:SAM23877 RS03770
gene id: 278992:SAM23877_RS03770
uniprot id: A3KJ74
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS19520
gene id: 278992:SAM23877_RS19520
uniprot id: A0A0K2AW10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

278992:SAM23877 RS03870
gene id: 278992:SAM23877_RS03870
uniprot id: A3KJ93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

278992:SAM23877 RS18655
gene id: 278992:SAM23877_RS18655
uniprot id: A0A0K2AV18
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

278992:SAM23877 RS31925
gene id: 278992:SAM23877_RS31925
uniprot id: A0ADK4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

278992:SAM23877 RS32560
gene id: 278992:SAM23877_RS32560
uniprot id: A0A0K2B495
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS24275
gene id: 278992:SAM23877_RS24275
uniprot id: A0A0K2AZ30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

278992:SAM23877 RS01520
gene id: 278992:SAM23877_RS01520
uniprot id: A3KHY0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

278992:SAM23877 RS20020
gene id: 278992:SAM23877_RS20020
uniprot id: A0A0K2AW74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

278992:SAM23877 RS11165
gene id: 278992:SAM23877_RS11165
uniprot id: A0A0K2AR71
names: Similarity
messages: Belongs to the UPF0246 family.

278992:SAM23877 RS07780
gene id: 278992:SAM23877_RS07780
uniprot id: A0A0K2AP17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS14065
gene id: 278992:SAM23877_RS14065
uniprot id: A0A0K2ASE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS26195
gene id: 278992:SAM23877_RS26195
uniprot id: A0A0K2B026
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

278992:SAM23877 RS26505
gene id: 278992:SAM23877_RS26505
uniprot id: A0A0K2B027
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

278992:SAM23877 RS15155
gene id: 278992:SAM23877_RS15155
uniprot id: A0A0K2AT11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm

278992:SAM23877 RS32450
gene id: 278992:SAM23877_RS32450
uniprot id: A0AD99
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS33120
gene id: 278992:SAM23877_RS33120
uniprot id: A0ACW4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

278992:SAM23877 RS30970
gene id: 278992:SAM23877_RS30970
uniprot id: A0AE43
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS30225
gene id: 278992:SAM23877_RS30225
uniprot id: A0A0K2B2H5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

278992:SAM23877 RS34650
gene id: 278992:SAM23877_RS34650
uniprot id: A0AC16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS30230
gene id: 278992:SAM23877_RS30230
uniprot id: A0A0K2B2A9
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

278992:SAM23877 RS31555
gene id: 278992:SAM23877_RS31555
uniprot id: A0ADS7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

278992:SAM23877 RS01530
gene id: 278992:SAM23877_RS01530
uniprot id: A3KHY2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

278992:SAM23877 RS21320
gene id: 278992:SAM23877_RS21320
uniprot id: A0A0K2AXC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm

278992:SAM23877 RS23540
gene id: 278992:SAM23877_RS23540
uniprot id: A0A0K2AYC0
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS32730
gene id: 278992:SAM23877_RS32730
uniprot id: A0AD41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.
messages: gas vesicle membrane

278992:SAM23877 RS12965
gene id: 278992:SAM23877_RS12965
uniprot id: A0A0K2ASA0
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS01445
gene id: 278992:SAM23877_RS01445
uniprot id: A3KHW5
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

278992:SAM23877 RS08505
gene id: 278992:SAM23877_RS08505
uniprot id: A0A0K2AP31
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

278992:SAM23877 RS35910
gene id: 278992:SAM23877_RS35910
uniprot id: Q1RR36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

278992:SAM23877 RS05880
gene id: 278992:SAM23877_RS05880
uniprot id: A3KKE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

278992:SAM23877 RS15275
gene id: 278992:SAM23877_RS15275
uniprot id: A0A0K2ATF9
names: Similarity
messages: Belongs to the peptidase S58 family.

278992:SAM23877 RS17910
gene id: 278992:SAM23877_RS17910
uniprot id: A0A0K2AV11
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

278992:SAM23877 RS07880
gene id: 278992:SAM23877_RS07880
uniprot id: A0A0K2AP36
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

278992:SAM23877 RS18705
gene id: 278992:SAM23877_RS18705
uniprot id: A0A0K2AV28
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS27065
gene id: 278992:SAM23877_RS27065
uniprot id: A0A0K2B0D4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

278992:SAM23877 RS15680
gene id: 278992:SAM23877_RS15680
uniprot id: A0A0K2ATC1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

278992:SAM23877 RS18850
gene id: 278992:SAM23877_RS18850
uniprot id: A0A0K2AVJ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

278992:SAM23877 RS19460
gene id: 278992:SAM23877_RS19460
uniprot id: A0A0K2AVJ6
names: Similarity
messages: Belongs to the GSP E family.

278992:SAM23877 RS07465
gene id: 278992:SAM23877_RS07465
uniprot id: A0A0K2ANV3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

278992:SAM23877 RS11185
gene id: 278992:SAM23877_RS11185
uniprot id: A0A0K2AQN7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

278992:SAM23877 RS28545
gene id: 278992:SAM23877_RS28545
uniprot id: A0A0K2B122
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

278992:SAM23877 RS31120
gene id: 278992:SAM23877_RS31120
uniprot id: A0AE14
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS31980
gene id: 278992:SAM23877_RS31980
uniprot id: A0ADJ3
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

278992:SAM23877 RS35525
gene id: 278992:SAM23877_RS35525
uniprot id: Q1RQV2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

278992:SAM23877 RS06495
gene id: 278992:SAM23877_RS06495
uniprot id: A3KKR9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

278992:SAM23877 RS07045
gene id: 278992:SAM23877_RS07045
uniprot id: A0A0K2ANK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

278992:SAM23877 RS08605
gene id: 278992:SAM23877_RS08605
uniprot id: A0A0K2APP9
names: Similarity
messages: Belongs to the TlyA family.

278992:SAM23877 RS24920
gene id: 278992:SAM23877_RS24920
uniprot id: A0A0K2AYT1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

278992:SAM23877 RS24445
gene id: 278992:SAM23877_RS24445
uniprot id: A0A0K2AZ65
names: Subcellular Location Annotation
messages: Cell membrane

278992:SAM23877 RS34720
gene id: 278992:SAM23877_RS34720
uniprot id: A0AC02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

278992:SAM23877 RS08105
gene id: 278992:SAM23877_RS08105
uniprot id: A0A0K2APL7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

278992:SAM23877 RS34165
gene id: 278992:SAM23877_RS34165
uniprot id: A0ACA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS12155
gene id: 278992:SAM23877_RS12155
uniprot id: A0A0K2ART6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

278992:SAM23877 RS27190
gene id: 278992:SAM23877_RS27190
uniprot id: A0A0K2B0G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS24805
gene id: 278992:SAM23877_RS24805
uniprot id: A0A0K2AZD8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

278992:SAM23877 RS33455
gene id: 278992:SAM23877_RS33455
uniprot id: A0ACP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

278992:SAM23877 RS05555
gene id: 278992:SAM23877_RS05555
uniprot id: A3KK80
names: Similarity
messages: Belongs to the UPF0047 family.

278992:SAM23877 RS09785
gene id: 278992:SAM23877_RS09785
uniprot id: A0A0K2AQM5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

278992:SAM23877 RS16460
gene id: 278992:SAM23877_RS16460
uniprot id: A0A0K2AU60
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

278992:SAM23877 RS23210
gene id: 278992:SAM23877_RS23210
uniprot id: A0A0K2AYE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS06890
gene id: 278992:SAM23877_RS06890
uniprot id: A3KKZ5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

278992:SAM23877 RS08785
gene id: 278992:SAM23877_RS08785
uniprot id: A0A0K2APJ8
names: Similarity
messages: Belongs to the peptidase U62 family.

278992:SAM23877 RS30460
gene id: 278992:SAM23877_RS30460
uniprot id: A0A0K2B2M2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

278992:SAM23877 RS09860
gene id: 278992:SAM23877_RS09860
uniprot id: A0A0K2AQP0
names: Similarity
messages: Belongs to the group II decarboxylase family.

278992:SAM23877 RS07870
gene id: 278992:SAM23877_RS07870
uniprot id: A0A0K2APH4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

278992:SAM23877 RS26545
gene id: 278992:SAM23877_RS26545
uniprot id: A0A0K2B0L8
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS10660
gene id: 278992:SAM23877_RS10660
uniprot id: A0A0K2AR67
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

278992:SAM23877 RS03250
gene id: 278992:SAM23877_RS03250
uniprot id: A3KIW8
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

278992:SAM23877 RS21440
gene id: 278992:SAM23877_RS21440
uniprot id: A0A0K2AWS4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

278992:SAM23877 RS23180
gene id: 278992:SAM23877_RS23180
uniprot id: A0A0K2AY89
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

278992:SAM23877 RS24225
gene id: 278992:SAM23877_RS24225
uniprot id: A0A0K2AYF0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

278992:SAM23877 RS31315
gene id: 278992:SAM23877_RS31315
uniprot id: A0ADX6
names: Similarity
messages: Belongs to the CapA family.

278992:SAM23877 RS10780
gene id: 278992:SAM23877_RS10780
uniprot id: A0A0K2AR89
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

278992:SAM23877 RS27055
gene id: 278992:SAM23877_RS27055
uniprot id: A0A0K2B0W3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS07210
gene id: 278992:SAM23877_RS07210
uniprot id: A0A0K2ANP2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

278992:SAM23877 RS14445
gene id: 278992:SAM23877_RS14445
uniprot id: A0A0K2ATH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

278992:SAM23877 RS19465
gene id: 278992:SAM23877_RS19465
uniprot id: A0A0K2AW78
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS03180
gene id: 278992:SAM23877_RS03180
uniprot id: A3KIV4
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

278992:SAM23877 RS20755
gene id: 278992:SAM23877_RS20755
uniprot id: A0A0K2AWR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

278992:SAM23877 RS11370
gene id: 278992:SAM23877_RS11370
uniprot id: A0A0K2ARL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

278992:SAM23877 RS24985
gene id: 278992:SAM23877_RS24985
uniprot id: A0A0K2AZ61
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS21740
gene id: 278992:SAM23877_RS21740
uniprot id: A0A0K2AXE4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS17930
gene id: 278992:SAM23877_RS17930
uniprot id: A0A0K2AVH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

278992:SAM23877 RS29905
gene id: 278992:SAM23877_RS29905
uniprot id: A0A0K2B2M1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

278992:SAM23877 RS25780
gene id: 278992:SAM23877_RS25780
uniprot id: A0A0K2AZM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

278992:SAM23877 RS07970
gene id: 278992:SAM23877_RS07970
uniprot id: A0A0K2AP34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

278992:SAM23877 RS10385
gene id: 278992:SAM23877_RS10385
uniprot id: A0A0K2AQI1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

278992:SAM23877 RS19615
gene id: 278992:SAM23877_RS19615
uniprot id: A0A0K2AVM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

278992:SAM23877 RS20150
gene id: 278992:SAM23877_RS20150
uniprot id: A0A0K2AW99
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

278992:SAM23877 RS08280
gene id: 278992:SAM23877_RS08280
uniprot id: A0A0K2APQ2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS21195
gene id: 278992:SAM23877_RS21195
uniprot id: A0A0K2AXA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

278992:SAM23877 RS08685
gene id: 278992:SAM23877_RS08685
uniprot id: A0A0K2APX8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

278992:SAM23877 RS21880
gene id: 278992:SAM23877_RS21880
uniprot id: A0A0K2AXW1
names: Similarity
messages: Belongs to the peptidase C40 family.

278992:SAM23877 RS35305
gene id: 278992:SAM23877_RS35305
uniprot id: Q1RQQ8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

278992:SAM23877 RS21380
gene id: 278992:SAM23877_RS21380
uniprot id: A0A0K2AX57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

278992:SAM23877 RS16740
gene id: 278992:SAM23877_RS16740
uniprot id: A0A0K2ATZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

278992:SAM23877 RS02830
gene id: 278992:SAM23877_RS02830
uniprot id: A3KIN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS30295
gene id: 278992:SAM23877_RS30295
uniprot id: A0A0K2B2J0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

278992:SAM23877 RS33490
gene id: 278992:SAM23877_RS33490
uniprot id: A0ACP1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

278992:SAM23877 RS11170
gene id: 278992:SAM23877_RS11170
uniprot id: A0A0K2ARG8
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

278992:SAM23877 RS21200
gene id: 278992:SAM23877_RS21200
uniprot id: A0A0K2AXH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

278992:SAM23877 RS14175
gene id: 278992:SAM23877_RS14175
uniprot id: A0A0K2ATB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

278992:SAM23877 RS06170
gene id: 278992:SAM23877_RS06170
uniprot id: A3KKK3
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

278992:SAM23877 RS11665
gene id: 278992:SAM23877_RS11665
uniprot id: A0A0K2ARB9
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS02935
gene id: 278992:SAM23877_RS02935
uniprot id: A0A0K2AL54
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS08815
gene id: 278992:SAM23877_RS08815
uniprot id: A0A0K2APA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

278992:SAM23877 RS07150
gene id: 278992:SAM23877_RS07150
uniprot id: A0A0K2ANW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

278992:SAM23877 RS25060
gene id: 278992:SAM23877_RS25060
uniprot id: A0A0K2AZI8
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

278992:SAM23877 RS28425
gene id: 278992:SAM23877_RS28425
uniprot id: A0A0K2B1G0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

278992:SAM23877 RS18295
gene id: 278992:SAM23877_RS18295
uniprot id: A0A0K2AUU2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

278992:SAM23877 RS08790
gene id: 278992:SAM23877_RS08790
uniprot id: A0A0K2APM4
names: Similarity
messages: Belongs to the peptidase U62 family.

278992:SAM23877 RS27430
gene id: 278992:SAM23877_RS27430
uniprot id: A0A0K2B0S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

278992:SAM23877 RS00310
gene id: 278992:SAM23877_RS00310
uniprot id: Q1RR19
names: Subcellular Location Annotation
messages: Cytoplasm

278992:SAM23877 RS29715
gene id: 278992:SAM23877_RS29715
uniprot id: A0A0K2B1P3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS30465
gene id: 278992:SAM23877_RS30465
uniprot id: A0A0K2B2G0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

278992:SAM23877 RS24185
gene id: 278992:SAM23877_RS24185
uniprot id: A0A0K2AZ88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

278992:SAM23877 RS17895
gene id: 278992:SAM23877_RS17895
uniprot id: A0A0K2AUK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

278992:SAM23877 RS14195
gene id: 278992:SAM23877_RS14195
uniprot id: A0A0K2ASW4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

278992:SAM23877 RS30650
gene id: 278992:SAM23877_RS30650
uniprot id: A0AEA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS21170
gene id: 278992:SAM23877_RS21170
uniprot id: A0A0K2AX98
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

278992:SAM23877 RS23015
gene id: 278992:SAM23877_RS23015
uniprot id: A0A0K2AXN3
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

278992:SAM23877 RS13675
gene id: 278992:SAM23877_RS13675
uniprot id: A0A0K2ASY8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

278992:SAM23877 RS13225
gene id: 278992:SAM23877_RS13225
uniprot id: A0A0K2ASA5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

278992:SAM23877 RS02990
gene id: 278992:SAM23877_RS02990
uniprot id: A3KIR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

278992:SAM23877 RS32650
gene id: 278992:SAM23877_RS32650
uniprot id: A0AD57
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

278992:SAM23877 RS15165
gene id: 278992:SAM23877_RS15165
uniprot id: A0A0K2ATG7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

278992:SAM23877 RS22935
gene id: 278992:SAM23877_RS22935
uniprot id: A0A0K2AXW9
names: Subcellular Location Annotation
messages: Cytoplasm

278992:SAM23877 RS14020
gene id: 278992:SAM23877_RS14020
uniprot id: A0A0K2ASE1
names: Similarity
messages: Belongs to the peptidase S16 family.

278992:SAM23877 RS15055
gene id: 278992:SAM23877_RS15055
uniprot id: A0A0K2ASZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

278992:SAM23877 RS20895
gene id: 278992:SAM23877_RS20895
uniprot id: A0A0K2AX22
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

278992:SAM23877 RS25035
gene id: 278992:SAM23877_RS25035
uniprot id: A0A0K2AYV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

278992:SAM23877 RS12140
gene id: 278992:SAM23877_RS12140
uniprot id: A0A0K2AS42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

278992:SAM23877 RS08075
gene id: 278992:SAM23877_RS08075
uniprot id: A0A0K2APE5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS21420
gene id: 278992:SAM23877_RS21420
uniprot id: A0A0K2AXE2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

278992:SAM23877 RS22040
gene id: 278992:SAM23877_RS22040
uniprot id: A0A0K2AXR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS22635
gene id: 278992:SAM23877_RS22635
uniprot id: A0A0K2AYB0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

278992:SAM23877 RS07220
gene id: 278992:SAM23877_RS07220
uniprot id: A0A0K2ANE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

278992:SAM23877 RS21115
gene id: 278992:SAM23877_RS21115
uniprot id: A0A0K2AX73
names: Similarity
messages: Belongs to the UPF0336 family.

278992:SAM23877 RS12515
gene id: 278992:SAM23877_RS12515
uniprot id: A0A0K2ASB3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

278992:SAM23877 RS07745
gene id: 278992:SAM23877_RS07745
uniprot id: A0A0K2AP77
names: Similarity
messages: Belongs to the glutamine synthetase family.

278992:SAM23877 RS30570
gene id: 278992:SAM23877_RS30570
uniprot id: A0AEC2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS19405
gene id: 278992:SAM23877_RS19405
uniprot id: A0A0K2AVI3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS24565
gene id: 278992:SAM23877_RS24565
uniprot id: A0A0K2AZ89
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS02810
gene id: 278992:SAM23877_RS02810
uniprot id: A3KIN0
names: Similarity
messages: Belongs to the YciI family.

278992:SAM23877 RS30415
gene id: 278992:SAM23877_RS30415
uniprot id: A0A0K2B2L1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

278992:SAM23877 RS23450
gene id: 278992:SAM23877_RS23450
uniprot id: A0A0K2AYS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS14560
gene id: 278992:SAM23877_RS14560
uniprot id: A0A0K2ATJ2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

278992:SAM23877 RS05410
gene id: 278992:SAM23877_RS05410
uniprot id: A3KK51
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

278992:SAM23877 RS29990
gene id: 278992:SAM23877_RS29990
uniprot id: A0A0K2B1V3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS17920
gene id: 278992:SAM23877_RS17920
uniprot id: A0A0K2AUK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

278992:SAM23877 RS20300
gene id: 278992:SAM23877_RS20300
uniprot id: A0A0K2AWP5
names: Similarity
messages: Belongs to the ice-binding protein family.

278992:SAM23877 RS32025
gene id: 278992:SAM23877_RS32025
uniprot id: A0ADI4
names: Similarity
messages: Belongs to the terpene synthase family.

278992:SAM23877 RS35380
gene id: 278992:SAM23877_RS35380
uniprot id: Q1RQS3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

278992:SAM23877 RS19705
gene id: 278992:SAM23877_RS19705
uniprot id: A0A0K2AW40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

278992:SAM23877 RS31040
gene id: 278992:SAM23877_RS31040
uniprot id: A0AE30
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

278992:SAM23877 RS10940
gene id: 278992:SAM23877_RS10940
uniprot id: A0A0K2AQI4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS09050
gene id: 278992:SAM23877_RS09050
uniprot id: A0A0K2APT1
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

278992:SAM23877 RS30160
gene id: 278992:SAM23877_RS30160
uniprot id: A0A0K2B1Y8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

278992:SAM23877 RS07995
gene id: 278992:SAM23877_RS07995
uniprot id: A0A0K2AP61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

278992:SAM23877 RS33565
gene id: 278992:SAM23877_RS33565
uniprot id: A0ACM6
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

278992:SAM23877 RS18730
gene id: 278992:SAM23877_RS18730
uniprot id: A0A0K2AV34
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS36625
gene id: 278992:SAM23877_RS36625
uniprot id: A0A0K2B6C3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS22610
gene id: 278992:SAM23877_RS22610
uniprot id: A0A0K2AYA5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

278992:SAM23877 RS08665
gene id: 278992:SAM23877_RS08665
uniprot id: A0A0K2APX3
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

278992:SAM23877 RS20405
gene id: 278992:SAM23877_RS20405
uniprot id: A0A0K2AWF6
names: Similarity
messages: Belongs to the UbiD family.

278992:SAM23877 RS03045
gene id: 278992:SAM23877_RS03045
uniprot id: A3KIS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS17815
gene id: 278992:SAM23877_RS17815
uniprot id: A0A0K2AVF3
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

278992:SAM23877 RS32325
gene id: 278992:SAM23877_RS32325
uniprot id: A0ADC3
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

278992:SAM23877 RS33745
gene id: 278992:SAM23877_RS33745
uniprot id: A0ACJ1
names: Similarity
messages: Belongs to the thioesterase family.

278992:SAM23877 RS14090
gene id: 278992:SAM23877_RS14090
uniprot id: A0A0K2ASF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS11570
gene id: 278992:SAM23877_RS11570
uniprot id: A0A0K2ARA0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

278992:SAM23877 RS24725
gene id: 278992:SAM23877_RS24725
uniprot id: A0A0K2AZ59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

278992:SAM23877 RS26055
gene id: 278992:SAM23877_RS26055
uniprot id: A0A0K2AZJ3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

278992:SAM23877 RS32985
gene id: 278992:SAM23877_RS32985
uniprot id: A0ACZ0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

278992:SAM23877 RS25105
gene id: 278992:SAM23877_RS25105
uniprot id: A0A0K2AZR6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

278992:SAM23877 RS10905
gene id: 278992:SAM23877_RS10905
uniprot id: A0A0K2ARB2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

278992:SAM23877 RS26045
gene id: 278992:SAM23877_RS26045
uniprot id: A0A0K2AZZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS29620
gene id: 278992:SAM23877_RS29620
uniprot id: A0A0K2B1M7
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

278992:SAM23877 RS12540
gene id: 278992:SAM23877_RS12540
uniprot id: A0A0K2ARU2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

278992:SAM23877 RS15450
gene id: 278992:SAM23877_RS15450
uniprot id: A0A0K2ATT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Vgb family.
messages: Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid.
messages: Monomer.

278992:SAM23877 RS10985
gene id: 278992:SAM23877_RS10985
uniprot id: A0A0K2AQX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

278992:SAM23877 RS33770
gene id: 278992:SAM23877_RS33770
uniprot id: A0ACI6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

278992:SAM23877 RS12415
gene id: 278992:SAM23877_RS12415
uniprot id: A0A0K2ARR8
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

278992:SAM23877 RS19945
gene id: 278992:SAM23877_RS19945
uniprot id: A0A0K2AW59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

278992:SAM23877 RS13245
gene id: 278992:SAM23877_RS13245
uniprot id: A0A0K2ASQ6
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

278992:SAM23877 RS02700
gene id: 278992:SAM23877_RS02700
uniprot id: A3KIK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS12375
gene id: 278992:SAM23877_RS12375
uniprot id: A0A0K2ARY6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

278992:SAM23877 RS19950
gene id: 278992:SAM23877_RS19950
uniprot id: A0A0K2AVT9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

278992:SAM23877 RS14705
gene id: 278992:SAM23877_RS14705
uniprot id: A0A0K2ASR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

278992:SAM23877 RS00610
gene id: 278992:SAM23877_RS00610
uniprot id: Q1RQV6
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

278992:SAM23877 RS10710
gene id: 278992:SAM23877_RS10710
uniprot id: A0A0K2AR78
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

278992:SAM23877 RS20925
gene id: 278992:SAM23877_RS20925
uniprot id: A0A0K2AWV0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

278992:SAM23877 RS10570
gene id: 278992:SAM23877_RS10570
uniprot id: A0A0K2AQA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

278992:SAM23877 RS14965
gene id: 278992:SAM23877_RS14965
uniprot id: A0A0K2ASW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

278992:SAM23877 RS14945
gene id: 278992:SAM23877_RS14945
uniprot id: A0A0K2ATG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

278992:SAM23877 RS24720
gene id: 278992:SAM23877_RS24720
uniprot id: A0A0K2AZI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS17635
gene id: 278992:SAM23877_RS17635
uniprot id: A0A0K2AUS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

278992:SAM23877 RS18465
gene id: 278992:SAM23877_RS18465
uniprot id: A0A0K2AV88
names: Similarity
messages: Belongs to the cytochrome P450 family.

278992:SAM23877 RS32210
gene id: 278992:SAM23877_RS32210
uniprot id: A0ADE7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

278992:SAM23877 RS12600
gene id: 278992:SAM23877_RS12600
uniprot id: A0A0K2ARV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

278992:SAM23877 RS04755
gene id: 278992:SAM23877_RS04755
uniprot id: A3KJR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS28230
gene id: 278992:SAM23877_RS28230
uniprot id: A0A0K2B139
names: Similarity
messages: Belongs to the catalase family.

278992:SAM23877 RS12605
gene id: 278992:SAM23877_RS12605
uniprot id: A0A0K2ARH4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

278992:SAM23877 RS16585
gene id: 278992:SAM23877_RS16585
uniprot id: A0A0K2AU81
names: Similarity
messages: Belongs to the Fur family.

278992:SAM23877 RS07280
gene id: 278992:SAM23877_RS07280
uniprot id: A0A0K2AP64
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

278992:SAM23877 RS31225
gene id: 278992:SAM23877_RS31225
uniprot id: A0ADZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

278992:SAM23877 RS26620
gene id: 278992:SAM23877_RS26620
uniprot id: A0A0K2B0N2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

278992:SAM23877 RS30585
gene id: 278992:SAM23877_RS30585
uniprot id: A0AEB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS06475
gene id: 278992:SAM23877_RS06475
uniprot id: A3KKR5
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

278992:SAM23877 RS22165
gene id: 278992:SAM23877_RS22165
uniprot id: A0A0K2AXT4
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS01100
gene id: 278992:SAM23877_RS01100
uniprot id: Q1RRD0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS16710
gene id: 278992:SAM23877_RS16710
uniprot id: A0A0K2AUA4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS27085
gene id: 278992:SAM23877_RS27085
uniprot id: A0A0K2B0J9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

278992:SAM23877 RS25330
gene id: 278992:SAM23877_RS25330
uniprot id: A0A0K2AZI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

278992:SAM23877 RS09400
gene id: 278992:SAM23877_RS09400
uniprot id: A0A0K2AQ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS21590
gene id: 278992:SAM23877_RS21590
uniprot id: A0A0K2AXQ7
names: Similarity
messages: Belongs to the YciI family.

278992:SAM23877 RS26560
gene id: 278992:SAM23877_RS26560
uniprot id: A0A0K2AZT5
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

278992:SAM23877 RS23425
gene id: 278992:SAM23877_RS23425
uniprot id: A0A0K2AYS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

278992:SAM23877 RS12030
gene id: 278992:SAM23877_RS12030
uniprot id: A0A0K2AS18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

278992:SAM23877 RS10190
gene id: 278992:SAM23877_RS10190
uniprot id: A0A0K2AQV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

278992:SAM23877 RS36540
gene id: 278992:SAM23877_RS36540
uniprot id: A0A0K2B6T7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

278992:SAM23877 RS25420
gene id: 278992:SAM23877_RS25420
uniprot id: A0A0K2AZX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

278992:SAM23877 RS14265
gene id: 278992:SAM23877_RS14265
uniprot id: A0A0K2ASX8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

278992:SAM23877 RS07455
gene id: 278992:SAM23877_RS07455
uniprot id: A0A0K2AP18
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

278992:SAM23877 RS19420
gene id: 278992:SAM23877_RS19420
uniprot id: A0A0K2AVV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

278992:SAM23877 RS14970
gene id: 278992:SAM23877_RS14970
uniprot id: A0A0K2ATS7
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS14570
gene id: 278992:SAM23877_RS14570
uniprot id: A0A0K2ASP0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

278992:SAM23877 RS31775
gene id: 278992:SAM23877_RS31775
uniprot id: A0A0K2B2Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

278992:SAM23877 RS19680
gene id: 278992:SAM23877_RS19680
uniprot id: A0A0K2AW35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

278992:SAM23877 RS29205
gene id: 278992:SAM23877_RS29205
uniprot id: A0A0K2B1X1
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

278992:SAM23877 RS15590
gene id: 278992:SAM23877_RS15590
uniprot id: A0A0K2ATA0
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

278992:SAM23877 RS29980
gene id: 278992:SAM23877_RS29980
uniprot id: A0A0K2B2C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

278992:SAM23877 RS03390
gene id: 278992:SAM23877_RS03390
uniprot id: A3KIZ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M7 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Secreted

278992:SAM23877 RS28605
gene id: 278992:SAM23877_RS28605
uniprot id: A0A0K2B1J5
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.

278992:SAM23877 RS27655
gene id: 278992:SAM23877_RS27655
uniprot id: A0A0K2B0R2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

278992:SAM23877 RS22060
gene id: 278992:SAM23877_RS22060
uniprot id: A0A0K2AX41
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

278992:SAM23877 RS06935
gene id: 278992:SAM23877_RS06935
uniprot id: A0A0K2ANZ8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

278992:SAM23877 RS33505
gene id: 278992:SAM23877_RS33505
uniprot id: A0ACN8
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS14460
gene id: 278992:SAM23877_RS14460
uniprot id: A0A0K2ASM3
names: Similarity
messages: Belongs to the PGI/PMI family.

278992:SAM23877 RS09625
gene id: 278992:SAM23877_RS09625
uniprot id: A0A0K2AQ54
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS05905
gene id: 278992:SAM23877_RS05905
uniprot id: A3KKF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

278992:SAM23877 RS27195
gene id: 278992:SAM23877_RS27195
uniprot id: A0A0K2B061
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

278992:SAM23877 RS13685
gene id: 278992:SAM23877_RS13685
uniprot id: A0A0K2ASG6
names: Similarity
messages: Belongs to the UPF0303 family.

278992:SAM23877 RS21515
gene id: 278992:SAM23877_RS21515
uniprot id: A0A0K2AWT9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

278992:SAM23877 RS24910
gene id: 278992:SAM23877_RS24910
uniprot id: A0A0K2AZA1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

278992:SAM23877 RS12735
gene id: 278992:SAM23877_RS12735
uniprot id: A0A0K2AS60
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

278992:SAM23877 RS12300
gene id: 278992:SAM23877_RS12300
uniprot id: A0A0K2AS70
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

278992:SAM23877 RS28240
gene id: 278992:SAM23877_RS28240
uniprot id: A0A0K2B1G6
names: Similarity
messages: Belongs to the hyi family.

278992:SAM23877 RS24925
gene id: 278992:SAM23877_RS24925
uniprot id: A0A0K2AZG1
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS13055
gene id: 278992:SAM23877_RS13055
uniprot id: A0A0K2ASL9
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

278992:SAM23877 RS11705
gene id: 278992:SAM23877_RS11705
uniprot id: A0A0K2ARK7
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

278992:SAM23877 RS13885
gene id: 278992:SAM23877_RS13885
uniprot id: A0A0K2AT39
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS07670
gene id: 278992:SAM23877_RS07670
uniprot id: A0A0K2AP63
names: Subcellular Location Annotation
messages: Cell membrane

278992:SAM23877 RS00785
gene id: 278992:SAM23877_RS00785
uniprot id: Q1RQS1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

278992:SAM23877 RS27125
gene id: 278992:SAM23877_RS27125
uniprot id: A0A0K2B0K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

278992:SAM23877 RS08255
gene id: 278992:SAM23877_RS08255
uniprot id: A0A0K2APP8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the homogentisate dioxygenase family.
messages: Hexamer; dimer of trimers.
messages: Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS32825
gene id: 278992:SAM23877_RS32825
uniprot id: A0AD23
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

278992:SAM23877 RS03875
gene id: 278992:SAM23877_RS03875
uniprot id: A3KJ94
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

278992:SAM23877 RS04090
gene id: 278992:SAM23877_RS04090
uniprot id: A3KJD6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

278992:SAM23877 RS06110
gene id: 278992:SAM23877_RS06110
uniprot id: A3KKJ2
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS03485
gene id: 278992:SAM23877_RS03485
uniprot id: A3KJ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS20325
gene id: 278992:SAM23877_RS20325
uniprot id: A0A0K2AWX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

278992:SAM23877 RS18735
gene id: 278992:SAM23877_RS18735
uniprot id: A0A0K2AVQ8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

278992:SAM23877 RS24075
gene id: 278992:SAM23877_RS24075
uniprot id: A0A0K2AYZ1
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS33735
gene id: 278992:SAM23877_RS33735
uniprot id: A0ACJ3
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

278992:SAM23877 RS05815
gene id: 278992:SAM23877_RS05815
uniprot id: A3KKD1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

278992:SAM23877 RS07040
gene id: 278992:SAM23877_RS07040
uniprot id: A0A0K2ANL3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS09540
gene id: 278992:SAM23877_RS09540
uniprot id: A0A0K2AQH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

278992:SAM23877 RS15145
gene id: 278992:SAM23877_RS15145
uniprot id: A0A0K2ATG2
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS20220
gene id: 278992:SAM23877_RS20220
uniprot id: A0A0K2AWE7
names: Subcellular Location Annotation
messages: Cell membrane

278992:SAM23877 RS02730
gene id: 278992:SAM23877_RS02730
uniprot id: A3KIL4
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

278992:SAM23877 RS17080
gene id: 278992:SAM23877_RS17080
uniprot id: A0A0K2AU47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS12580
gene id: 278992:SAM23877_RS12580
uniprot id: A0A0K2ARG9
names: Similarity
messages: Belongs to the FPG family.

278992:SAM23877 RS35060
gene id: 278992:SAM23877_RS35060
uniprot id: A0A0K2B5M3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS22215
gene id: 278992:SAM23877_RS22215
uniprot id: A0A0K2AY24
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS24715
gene id: 278992:SAM23877_RS24715
uniprot id: A0A0K2AZB9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

278992:SAM23877 RS21500
gene id: 278992:SAM23877_RS21500
uniprot id: A0A0K2AXF5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

278992:SAM23877 RS29365
gene id: 278992:SAM23877_RS29365
uniprot id: A0A0K2B204
names: Similarity
messages: Belongs to the peptidase S66 family.

278992:SAM23877 RS17550
gene id: 278992:SAM23877_RS17550
uniprot id: A0A0K2AV15
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

278992:SAM23877 RS35370
gene id: 278992:SAM23877_RS35370
uniprot id: Q1RQS1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

278992:SAM23877 RS21045
gene id: 278992:SAM23877_RS21045
uniprot id: A0A0K2AXD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

278992:SAM23877 RS04435
gene id: 278992:SAM23877_RS04435
uniprot id: A3KJK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

278992:SAM23877 RS07585
gene id: 278992:SAM23877_RS07585
uniprot id: A0A0K2ANV2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

278992:SAM23877 RS24305
gene id: 278992:SAM23877_RS24305
uniprot id: A0A0K2AZB2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

278992:SAM23877 RS21390
gene id: 278992:SAM23877_RS21390
uniprot id: A0A0K2AWR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

278992:SAM23877 RS03110
gene id: 278992:SAM23877_RS03110
uniprot id: A0A0K2AKZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS21415
gene id: 278992:SAM23877_RS21415
uniprot id: A0A0K2AWS0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

278992:SAM23877 RS10740
gene id: 278992:SAM23877_RS10740
uniprot id: A0A0K2AQQ5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

278992:SAM23877 RS20820
gene id: 278992:SAM23877_RS20820
uniprot id: A0A0K2AX08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

278992:SAM23877 RS14880
gene id: 278992:SAM23877_RS14880
uniprot id: A0A0K2ATR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

278992:SAM23877 RS10150
gene id: 278992:SAM23877_RS10150
uniprot id: A0A0K2AQF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

278992:SAM23877 RS00725
gene id: 278992:SAM23877_RS00725
uniprot id: Q1RQT3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

278992:SAM23877 RS20355
gene id: 278992:SAM23877_RS20355
uniprot id: A0A0K2AWH5
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS15290
gene id: 278992:SAM23877_RS15290
uniprot id: A0A0K2ATY9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

278992:SAM23877 RS10875
gene id: 278992:SAM23877_RS10875
uniprot id: A0A0K2AR10
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

278992:SAM23877 RS28370
gene id: 278992:SAM23877_RS28370
uniprot id: A0A0K2B1Q8
names: Similarity
messages: Belongs to the allantoicase family.

278992:SAM23877 RS12660
gene id: 278992:SAM23877_RS12660
uniprot id: A0A0K2AS46
names: Similarity
messages: Belongs to the peptidase M1 family.

278992:SAM23877 RS32905
gene id: 278992:SAM23877_RS32905
uniprot id: A0AD07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

278992:SAM23877 RS31380
gene id: 278992:SAM23877_RS31380
uniprot id: A0ADW2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS12495
gene id: 278992:SAM23877_RS12495
uniprot id: A0A0K2ASB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

278992:SAM23877 RS15925
gene id: 278992:SAM23877_RS15925
uniprot id: A0A0K2AU36
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

278992:SAM23877 RS33390
gene id: 278992:SAM23877_RS33390
uniprot id: A0ACR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

278992:SAM23877 RS17770
gene id: 278992:SAM23877_RS17770
uniprot id: A0A0K2AUX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

278992:SAM23877 RS22415
gene id: 278992:SAM23877_RS22415
uniprot id: A0A0K2AXT1
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS05400
gene id: 278992:SAM23877_RS05400
uniprot id: A3KK49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 3 family.
messages: Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%, with an endo mode of action. In contrast to the majority of pectate lyases, displays high activity on highly methylated pectins.
messages: Secreted

278992:SAM23877 RS11210
gene id: 278992:SAM23877_RS11210
uniprot id: A0A0K2ARH8
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS07240
gene id: 278992:SAM23877_RS07240
uniprot id: A0A0K2ANP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

278992:SAM23877 RS12625
gene id: 278992:SAM23877_RS12625
uniprot id: A0A0K2ARV7
names: Similarity
messages: Belongs to the peptidase M1 family.

278992:SAM23877 RS19185
gene id: 278992:SAM23877_RS19185
uniprot id: A0A0K2AWA5
names: Similarity
messages: Belongs to the AdoMet synthetase 2 family.

278992:SAM23877 RS15475
gene id: 278992:SAM23877_RS15475
uniprot id: A0A0K2ATT7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

278992:SAM23877 RS34415
gene id: 278992:SAM23877_RS34415
uniprot id: A0AC61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS23140
gene id: 278992:SAM23877_RS23140
uniprot id: A0A0K2AXQ9
names: Similarity
messages: Belongs to the peptidase S8 family.

278992:SAM23877 RS29940
gene id: 278992:SAM23877_RS29940
uniprot id: A0A0K2B249
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

278992:SAM23877 RS25745
gene id: 278992:SAM23877_RS25745
uniprot id: A0A0K2B038
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

278992:SAM23877 RS10565
gene id: 278992:SAM23877_RS10565
uniprot id: A0A0K2AQN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

278992:SAM23877 RS17535
gene id: 278992:SAM23877_RS17535
uniprot id: A0A0K2AUS5
names: Similarity
messages: Belongs to the SCO1/2 family.

278992:SAM23877 RS21035
gene id: 278992:SAM23877_RS21035
uniprot id: A0A0K2AWI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

278992:SAM23877 RS32585
gene id: 278992:SAM23877_RS32585
uniprot id: A0AD72
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

278992:SAM23877 RS27665
gene id: 278992:SAM23877_RS27665
uniprot id: A0A0K2B138
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

278992:SAM23877 RS07620
gene id: 278992:SAM23877_RS07620
uniprot id: A0A0K2AP53
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

278992:SAM23877 RS20195
gene id: 278992:SAM23877_RS20195
uniprot id: A0A0K2AWE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

278992:SAM23877 RS22680
gene id: 278992:SAM23877_RS22680
uniprot id: A0A0K2AY38
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

278992:SAM23877 RS32120
gene id: 278992:SAM23877_RS32120
uniprot id: A0ADG5
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

278992:SAM23877 RS17850
gene id: 278992:SAM23877_RS17850
uniprot id: A0A0K2AUJ7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS12060
gene id: 278992:SAM23877_RS12060
uniprot id: A0A0K2ARJ0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

278992:SAM23877 RS24750
gene id: 278992:SAM23877_RS24750
uniprot id: A0A0K2AZ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS27880
gene id: 278992:SAM23877_RS27880
uniprot id: A0A0K2B0V5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

278992:SAM23877 RS01875
gene id: 278992:SAM23877_RS01875
uniprot id: A3KI52
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

278992:SAM23877 RS31890
gene id: 278992:SAM23877_RS31890
uniprot id: A0ADL1
names: Similarity
messages: Belongs to the cytochrome P450 family.

278992:SAM23877 RS35520
gene id: 278992:SAM23877_RS35520
uniprot id: A0A0K2AJL7
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

278992:SAM23877 RS27600
gene id: 278992:SAM23877_RS27600
uniprot id: A0A0K2B0W1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

278992:SAM23877 RS27690
gene id: 278992:SAM23877_RS27690
uniprot id: A0A0K2B143
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS23270
gene id: 278992:SAM23877_RS23270
uniprot id: A0A0K2AYA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS08135
gene id: 278992:SAM23877_RS08135
uniprot id: A0A0K2AP68
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

278992:SAM23877 RS21345
gene id: 278992:SAM23877_RS21345
uniprot id: A0A0K2AXD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

278992:SAM23877 RS22175
gene id: 278992:SAM23877_RS22175
uniprot id: A0A0K2AXN0
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

278992:SAM23877 RS26175
gene id: 278992:SAM23877_RS26175
uniprot id: A0A0K2AZW6
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

278992:SAM23877 RS20500
gene id: 278992:SAM23877_RS20500
uniprot id: A0A0K2AW54
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

278992:SAM23877 RS20165
gene id: 278992:SAM23877_RS20165
uniprot id: A0A0K2AWU6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS07015
gene id: 278992:SAM23877_RS07015
uniprot id: A0A0K2ANK9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

278992:SAM23877 RS14060
gene id: 278992:SAM23877_RS14060
uniprot id: A0A0K2ASR3
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

278992:SAM23877 RS30395
gene id: 278992:SAM23877_RS30395
uniprot id: A0A0K2B2E2
names: Cofactor
messages: Binds 1 zinc ion per subunit.

278992:SAM23877 RS16255
gene id: 278992:SAM23877_RS16255
uniprot id: A0A0K2AU15
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

278992:SAM23877 RS30440
gene id: 278992:SAM23877_RS30440
uniprot id: A0A0K2B2F4
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

278992:SAM23877 RS04110
gene id: 278992:SAM23877_RS04110
uniprot id: A3KJE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

278992:SAM23877 RS22850
gene id: 278992:SAM23877_RS22850
uniprot id: A0A0K2AXJ3
names: Similarity
messages: Belongs to the GSP E family.

278992:SAM23877 RS17355
gene id: 278992:SAM23877_RS17355
uniprot id: A0A0K2AUX5
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS35300
gene id: 278992:SAM23877_RS35300
uniprot id: Q1RQQ7
names: Similarity
messages: Belongs to the thioesterase family.

278992:SAM23877 RS22025
gene id: 278992:SAM23877_RS22025
uniprot id: A0A0K2AXJ9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

278992:SAM23877 RS09160
gene id: 278992:SAM23877_RS09160
uniprot id: A0A0K2AQ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS18740
gene id: 278992:SAM23877_RS18740
uniprot id: A0A0K2AVZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

278992:SAM23877 RS25010
gene id: 278992:SAM23877_RS25010
uniprot id: A0A0K2AZ66
names: Cofactor
messages: Binds 1 FAD per subunit.

278992:SAM23877 RS12635
gene id: 278992:SAM23877_RS12635
uniprot id: A0A0K2AS41
names: Similarity
messages: Belongs to the peptidase S8 family.

278992:SAM23877 RS19900
gene id: 278992:SAM23877_RS19900
uniprot id: A0A0K2AVT1
names: Subcellular Location Annotation
messages: Cell membrane

278992:SAM23877 RS05740
gene id: 278992:SAM23877_RS05740
uniprot id: A3KKB6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

278992:SAM23877 RS21075
gene id: 278992:SAM23877_RS21075
uniprot id: A0A0K2AWY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

278992:SAM23877 RS07580
gene id: 278992:SAM23877_RS07580
uniprot id: A0A0K2APB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

278992:SAM23877 RS26020
gene id: 278992:SAM23877_RS26020
uniprot id: A0A0K2AZZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

278992:SAM23877 RS05995
gene id: 278992:SAM23877_RS05995
uniprot id: A3KKG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

278992:SAM23877 RS12490
gene id: 278992:SAM23877_RS12490
uniprot id: A0A0K2AS10
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

278992:SAM23877 RS09995
gene id: 278992:SAM23877_RS09995
uniprot id: A0A0K2APZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

278992:SAM23877 RS10175
gene id: 278992:SAM23877_RS10175
uniprot id: A0A0K2AQF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

278992:SAM23877 RS10220
gene id: 278992:SAM23877_RS10220
uniprot id: A0A0K2AQE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

278992:SAM23877 RS08235
gene id: 278992:SAM23877_RS08235
uniprot id: A0A0K2AP88
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS26150
gene id: 278992:SAM23877_RS26150
uniprot id: A0A0K2AZW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

278992:SAM23877 RS19660
gene id: 278992:SAM23877_RS19660
uniprot id: A0A0K2AW00
names: Similarity
messages: Belongs to the group II decarboxylase family.

278992:SAM23877 RS22945
gene id: 278992:SAM23877_RS22945
uniprot id: A0A0K2AY95
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS27455
gene id: 278992:SAM23877_RS27455
uniprot id: A0A0K2B0T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS30070
gene id: 278992:SAM23877_RS30070
uniprot id: A0A0K2B2K4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS05890
gene id: 278992:SAM23877_RS05890
uniprot id: A3KKE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS23100
gene id: 278992:SAM23877_RS23100
uniprot id: A0A0K2AYK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS13460
gene id: 278992:SAM23877_RS13460
uniprot id: A0A0K2ASK1
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

278992:SAM23877 RS24200
gene id: 278992:SAM23877_RS24200
uniprot id: A0A0K2AYE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

278992:SAM23877 RS21410
gene id: 278992:SAM23877_RS21410
uniprot id: A0A0K2AX19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

278992:SAM23877 RS20465
gene id: 278992:SAM23877_RS20465
uniprot id: A0A0K2AWT2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

278992:SAM23877 RS26050
gene id: 278992:SAM23877_RS26050
uniprot id: A0A0K2AZU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS01585
gene id: 278992:SAM23877_RS01585
uniprot id: A3KHZ3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS22310
gene id: 278992:SAM23877_RS22310
uniprot id: A0A0K2AXW3
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Belongs to the KdsC family.
messages: Homotetramer.

278992:SAM23877 RS28815
gene id: 278992:SAM23877_RS28815
uniprot id: A0A0K2B1U7
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

278992:SAM23877 RS14340
gene id: 278992:SAM23877_RS14340
uniprot id: A0A0K2ATF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

278992:SAM23877 RS08390
gene id: 278992:SAM23877_RS08390
uniprot id: A0A0K2APK4
names: Similarity
messages: Belongs to the peptidase S1 family.

278992:SAM23877 RS07395
gene id: 278992:SAM23877_RS07395
uniprot id: A0A0K2ANS4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

278992:SAM23877 RS03480
gene id: 278992:SAM23877_RS03480
uniprot id: A3KJ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS24990
gene id: 278992:SAM23877_RS24990
uniprot id: A0A0K2AYU6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

278992:SAM23877 RS18830
gene id: 278992:SAM23877_RS18830
uniprot id: A0A0K2AV72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS27525
gene id: 278992:SAM23877_RS27525
uniprot id: A0A0K2B155
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

278992:SAM23877 RS25335
gene id: 278992:SAM23877_RS25335
uniprot id: A0A0K2AZD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

278992:SAM23877 RS29335
gene id: 278992:SAM23877_RS29335
uniprot id: A0A0K2B2B0
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS31155
gene id: 278992:SAM23877_RS31155
uniprot id: A0AE07
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS11325
gene id: 278992:SAM23877_RS11325
uniprot id: A0A0K2AR97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

278992:SAM23877 RS25870
gene id: 278992:SAM23877_RS25870
uniprot id: A0A0K2AZD9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

278992:SAM23877 RS28600
gene id: 278992:SAM23877_RS28600
uniprot id: A0A0K2B1V5
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

278992:SAM23877 RS03840
gene id: 278992:SAM23877_RS03840
uniprot id: A3KJ87
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

278992:SAM23877 RS06630
gene id: 278992:SAM23877_RS06630
uniprot id: A3KKU5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

278992:SAM23877 RS07285
gene id: 278992:SAM23877_RS07285
uniprot id: A0A0K2ANQ9
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

278992:SAM23877 RS17015
gene id: 278992:SAM23877_RS17015
uniprot id: A0A0K2AU37
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

278992:SAM23877 RS33345
gene id: 278992:SAM23877_RS33345
uniprot id: A0ACS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

278992:SAM23877 RS21215
gene id: 278992:SAM23877_RS21215
uniprot id: A0A0K2AWN8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

278992:SAM23877 RS10010
gene id: 278992:SAM23877_RS10010
uniprot id: A0A0K2AQA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

278992:SAM23877 RS25375
gene id: 278992:SAM23877_RS25375
uniprot id: A0A0K2AZJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

278992:SAM23877 RS18350
gene id: 278992:SAM23877_RS18350
uniprot id: A0A0K2AVH7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

278992:SAM23877 RS04150
gene id: 278992:SAM23877_RS04150
uniprot id: A3KJE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

278992:SAM23877 RS03340
gene id: 278992:SAM23877_RS03340
uniprot id: A3KIY5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS25800
gene id: 278992:SAM23877_RS25800
uniprot id: A0A0K2AZM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

278992:SAM23877 RS10205
gene id: 278992:SAM23877_RS10205
uniprot id: A0A0K2AQ33
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS24145
gene id: 278992:SAM23877_RS24145
uniprot id: A0A0K2AYD5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

278992:SAM23877 RS26650
gene id: 278992:SAM23877_RS26650
uniprot id: A0A0K2B0B3
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

278992:SAM23877 RS14450
gene id: 278992:SAM23877_RS14450
uniprot id: A0A0K2AT16
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS21940
gene id: 278992:SAM23877_RS21940
uniprot id: A0A0K2AXB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

278992:SAM23877 RS35295
gene id: 278992:SAM23877_RS35295
uniprot id: Q1RQQ6
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

278992:SAM23877 RS23675
gene id: 278992:SAM23877_RS23675
uniprot id: A0A0K2AYE6
names: Similarity
messages: Belongs to the catalase family.

278992:SAM23877 RS09610
gene id: 278992:SAM23877_RS09610
uniprot id: A0A0K2AQB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

278992:SAM23877 RS10775
gene id: 278992:SAM23877_RS10775
uniprot id: A0A0K2AQZ3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS20745
gene id: 278992:SAM23877_RS20745
uniprot id: A0A0K2AWB2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

278992:SAM23877 RS24605
gene id: 278992:SAM23877_RS24605
uniprot id: A0A0K2AYX7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

278992:SAM23877 RS25815
gene id: 278992:SAM23877_RS25815
uniprot id: A0A0K2AZT2
names: Similarity
messages: Belongs to the ribF family.

278992:SAM23877 RS32595
gene id: 278992:SAM23877_RS32595
uniprot id: A0AD68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.
messages: Belongs to the glycosyl hydrolase 46 family.
messages: Secreted

278992:SAM23877 RS13535
gene id: 278992:SAM23877_RS13535
uniprot id: A0A0K2ASL7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

278992:SAM23877 RS25730
gene id: 278992:SAM23877_RS25730
uniprot id: A0A0K2AZL1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

278992:SAM23877 RS04010
gene id: 278992:SAM23877_RS04010
uniprot id: A3KJC0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

278992:SAM23877 RS29670
gene id: 278992:SAM23877_RS29670
uniprot id: A0A0K2B1N5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS15230
gene id: 278992:SAM23877_RS15230
uniprot id: A0A0K2ATH5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

278992:SAM23877 RS29445
gene id: 278992:SAM23877_RS29445
uniprot id: A0A0K2B1U4
names: Function
names: Similarity
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.

278992:SAM23877 RS19555
gene id: 278992:SAM23877_RS19555
uniprot id: A0A0K2AVY0
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

278992:SAM23877 RS21495
gene id: 278992:SAM23877_RS21495
uniprot id: A0A0K2AWT4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

278992:SAM23877 RS19915
gene id: 278992:SAM23877_RS19915
uniprot id: A0A0K2AW85
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS25325
gene id: 278992:SAM23877_RS25325
uniprot id: A0A0K2AZV6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

278992:SAM23877 RS23650
gene id: 278992:SAM23877_RS23650
uniprot id: A0A0K2AY47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

278992:SAM23877 RS07010
gene id: 278992:SAM23877_RS07010
uniprot id: A0A0K2AP10
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

278992:SAM23877 RS11330
gene id: 278992:SAM23877_RS11330
uniprot id: A0A0K2AR32
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS03625
gene id: 278992:SAM23877_RS03625
uniprot id: A3KJ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS20275
gene id: 278992:SAM23877_RS20275
uniprot id: A0A0K2AW08
names: Subcellular Location Annotation
messages: Cytoplasm

278992:SAM23877 RS12245
gene id: 278992:SAM23877_RS12245
uniprot id: A0A0K2ARN0
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

278992:SAM23877 RS06440
gene id: 278992:SAM23877_RS06440
uniprot id: A3KKQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

278992:SAM23877 RS25465
gene id: 278992:SAM23877_RS25465
uniprot id: A0A0K2AZS2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

278992:SAM23877 RS13835
gene id: 278992:SAM23877_RS13835
uniprot id: A0A0K2ASN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

278992:SAM23877 RS04495
gene id: 278992:SAM23877_RS04495
uniprot id: A3KJL7
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS21795
gene id: 278992:SAM23877_RS21795
uniprot id: A0A0K2AX89
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

278992:SAM23877 RS21960
gene id: 278992:SAM23877_RS21960
uniprot id: A0A0K2AXB8
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

278992:SAM23877 RS18165
gene id: 278992:SAM23877_RS18165
uniprot id: A0A0K2AUR6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

278992:SAM23877 RS11950
gene id: 278992:SAM23877_RS11950
uniprot id: A0A0K2ARQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS12045
gene id: 278992:SAM23877_RS12045
uniprot id: A0A0K2ARR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS13435
gene id: 278992:SAM23877_RS13435
uniprot id: A0A0K2ASJ6
names: Similarity
messages: Belongs to the TPP enzyme family.

278992:SAM23877 RS27310
gene id: 278992:SAM23877_RS27310
uniprot id: A0A0K2B0I9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS26230
gene id: 278992:SAM23877_RS26230
uniprot id: A0A0K2AZM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

278992:SAM23877 RS21400
gene id: 278992:SAM23877_RS21400
uniprot id: A0A0K2AXL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

278992:SAM23877 RS21240
gene id: 278992:SAM23877_RS21240
uniprot id: A0A0K2AXB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

278992:SAM23877 RS18745
gene id: 278992:SAM23877_RS18745
uniprot id: A0A0K2AVI0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

278992:SAM23877 RS22860
gene id: 278992:SAM23877_RS22860
uniprot id: A0A0K2AYF4
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS13475
gene id: 278992:SAM23877_RS13475
uniprot id: A0A0K2ASC3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS12785
gene id: 278992:SAM23877_RS12785
uniprot id: A0A0K2AS68
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

278992:SAM23877 RS14795
gene id: 278992:SAM23877_RS14795
uniprot id: A0A0K2AT87
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS21460
gene id: 278992:SAM23877_RS21460
uniprot id: A0A0K2AX71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

278992:SAM23877 RS17900
gene id: 278992:SAM23877_RS17900
uniprot id: A0A0K2AV87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

278992:SAM23877 RS34665
gene id: 278992:SAM23877_RS34665
uniprot id: A0AC13
names: Similarity
messages: Belongs to the peptidase S8 family.

278992:SAM23877 RS12590
gene id: 278992:SAM23877_RS12590
uniprot id: A0A0K2ASC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

278992:SAM23877 RS16755
gene id: 278992:SAM23877_RS16755
uniprot id: A0A0K2AUD7
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

278992:SAM23877 RS22720
gene id: 278992:SAM23877_RS22720
uniprot id: A0A0K2AXS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

278992:SAM23877 RS05775
gene id: 278992:SAM23877_RS05775
uniprot id: A3KKC3
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

278992:SAM23877 RS06990
gene id: 278992:SAM23877_RS06990
uniprot id: A0A0K2ANK4
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS06955
gene id: 278992:SAM23877_RS06955
uniprot id: A0A0K2ANS8
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

278992:SAM23877 RS04725
gene id: 278992:SAM23877_RS04725
uniprot id: A3KJR3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

278992:SAM23877 RS27220
gene id: 278992:SAM23877_RS27220
uniprot id: A0A0K2B065
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS24880
gene id: 278992:SAM23877_RS24880
uniprot id: A0A0K2AZF3
names: Similarity
messages: Belongs to the LOG family.

278992:SAM23877 RS21535
gene id: 278992:SAM23877_RS21535
uniprot id: A0A0K2AX42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

278992:SAM23877 RS18540
gene id: 278992:SAM23877_RS18540
uniprot id: A0A0K2AUZ2
names: Subcellular Location Annotation
messages: Cell membrane

278992:SAM23877 RS32620
gene id: 278992:SAM23877_RS32620
uniprot id: A0AD63
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

278992:SAM23877 RS05530
gene id: 278992:SAM23877_RS05530
uniprot id: A3KK75
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS23295
gene id: 278992:SAM23877_RS23295
uniprot id: A0A0K2AYB1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

278992:SAM23877 RS34350
gene id: 278992:SAM23877_RS34350
uniprot id: A0A0K2B560
names: Similarity
messages: Belongs to the Nudix hydrolase family.

278992:SAM23877 RS31000
gene id: 278992:SAM23877_RS31000
uniprot id: A0AE38
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS33740
gene id: 278992:SAM23877_RS33740
uniprot id: A0ACJ2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

278992:SAM23877 RS16575
gene id: 278992:SAM23877_RS16575
uniprot id: A0A0K2AUS2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

278992:SAM23877 RS08470
gene id: 278992:SAM23877_RS08470
uniprot id: A0A0K2APD8
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

278992:SAM23877 RS28415
gene id: 278992:SAM23877_RS28415
uniprot id: A0A0K2B1M0
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS23045
gene id: 278992:SAM23877_RS23045
uniprot id: A0A0K2AYB2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

278992:SAM23877 RS29460
gene id: 278992:SAM23877_RS29460
uniprot id: A0A0K2B2D2
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

278992:SAM23877 RS24250
gene id: 278992:SAM23877_RS24250
uniprot id: A0A0K2AYF5
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS25620
gene id: 278992:SAM23877_RS25620
uniprot id: A0A0K2B012
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

278992:SAM23877 RS11620
gene id: 278992:SAM23877_RS11620
uniprot id: A0A0K2ARA9
names: Similarity
messages: Belongs to the OsmC/Ohr family.

278992:SAM23877 RS03915
gene id: 278992:SAM23877_RS03915
uniprot id: A3KJA2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

278992:SAM23877 RS31020
gene id: 278992:SAM23877_RS31020
uniprot id: A0A0K2B3C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

278992:SAM23877 RS21140
gene id: 278992:SAM23877_RS21140
uniprot id: A0A0K2AX94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

278992:SAM23877 RS21430
gene id: 278992:SAM23877_RS21430
uniprot id: A0A0K2AX66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

278992:SAM23877 RS21110
gene id: 278992:SAM23877_RS21110
uniprot id: A0A0K2AWJ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

278992:SAM23877 RS13875
gene id: 278992:SAM23877_RS13875
uniprot id: A0A0K2AS86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

278992:SAM23877 RS04810
gene id: 278992:SAM23877_RS04810
uniprot id: A3KJT1
names: Similarity
messages: Belongs to the EccD/Snm4 family.

278992:SAM23877 RS26930
gene id: 278992:SAM23877_RS26930
uniprot id: A0A0K2B0A4
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS11715
gene id: 278992:SAM23877_RS11715
uniprot id: A0A0K2ARC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS20010
gene id: 278992:SAM23877_RS20010
uniprot id: A0A0K2AWR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS20110
gene id: 278992:SAM23877_RS20110
uniprot id: A0A0K2AWK9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

278992:SAM23877 RS34360
gene id: 278992:SAM23877_RS34360
uniprot id: A0AC72
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

278992:SAM23877 RS30610
gene id: 278992:SAM23877_RS30610
uniprot id: A0AEB4
names: Similarity
messages: Belongs to the glutamine synthetase family.

278992:SAM23877 RS12325
gene id: 278992:SAM23877_RS12325
uniprot id: A0A0K2AS74
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS06620
gene id: 278992:SAM23877_RS06620
uniprot id: A3KKU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

278992:SAM23877 RS13220
gene id: 278992:SAM23877_RS13220
uniprot id: A0A0K2ASQ2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

278992:SAM23877 RS22820
gene id: 278992:SAM23877_RS22820
uniprot id: A0A0K2AXU5
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

278992:SAM23877 RS34145
gene id: 278992:SAM23877_RS34145
uniprot id: A0ACB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS04265
gene id: 278992:SAM23877_RS04265
uniprot id: A3KJH1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

278992:SAM23877 RS26685
gene id: 278992:SAM23877_RS26685
uniprot id: A0A0K2AZV8
names: Similarity
messages: Belongs to the CdaR family.

278992:SAM23877 RS12475
gene id: 278992:SAM23877_RS12475
uniprot id: A0A0K2ASA6
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS00850
gene id: 278992:SAM23877_RS00850
uniprot id: Q1RQQ8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

278992:SAM23877 RS15495
gene id: 278992:SAM23877_RS15495
uniprot id: A0A0K2AT80
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS19820
gene id: 278992:SAM23877_RS19820
uniprot id: A0A0K2AWE4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

278992:SAM23877 RS15095
gene id: 278992:SAM23877_RS15095
uniprot id: A0A0K2ATF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

278992:SAM23877 RS20015
gene id: 278992:SAM23877_RS20015
uniprot id: A0A0K2AWA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

278992:SAM23877 RS06045
gene id: 278992:SAM23877_RS06045
uniprot id: A3KKH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS06395
gene id: 278992:SAM23877_RS06395
uniprot id: A3KKP8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS15105
gene id: 278992:SAM23877_RS15105
uniprot id: A0A0K2AT01
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS24220
gene id: 278992:SAM23877_RS24220
uniprot id: A0A0K2AYP5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

278992:SAM23877 RS23670
gene id: 278992:SAM23877_RS23670
uniprot id: A0A0K2AYL6
names: Similarity
messages: Belongs to the Fur family.

278992:SAM23877 RS08600
gene id: 278992:SAM23877_RS08600
uniprot id: A0A0K2AP54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS09570
gene id: 278992:SAM23877_RS09570
uniprot id: A0A0K2AQ18
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

278992:SAM23877 RS35285
gene id: 278992:SAM23877_RS35285
uniprot id: Q1RQQ4
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

278992:SAM23877 RS27605
gene id: 278992:SAM23877_RS27605
uniprot id: A0A0K2B0Q1
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

278992:SAM23877 RS32675
gene id: 278992:SAM23877_RS32675
uniprot id: A0AD52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS19035
gene id: 278992:SAM23877_RS19035
uniprot id: A0A0K2AVM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

278992:SAM23877 RS08220
gene id: 278992:SAM23877_RS08220
uniprot id: A0A0K2ANX5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

278992:SAM23877 RS24295
gene id: 278992:SAM23877_RS24295
uniprot id: A0A0K2AYG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

278992:SAM23877 RS21040
gene id: 278992:SAM23877_RS21040
uniprot id: A0A0K2AX58
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS09545
gene id: 278992:SAM23877_RS09545
uniprot id: A0A0K2AQ14
names: Similarity
messages: Belongs to the peptidase S66 family.

278992:SAM23877 RS07000
gene id: 278992:SAM23877_RS07000
uniprot id: A0A0K2ANB2
names: Similarity
messages: Belongs to the barstar family.

278992:SAM23877 RS17570
gene id: 278992:SAM23877_RS17570
uniprot id: A0A0K2AV21
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS05175
gene id: 278992:SAM23877_RS05175
uniprot id: A3KK06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS18025
gene id: 278992:SAM23877_RS18025
uniprot id: A0A0K2AVB3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS03035
gene id: 278992:SAM23877_RS03035
uniprot id: A3KIS5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

278992:SAM23877 RS01285
gene id: 278992:SAM23877_RS01285
uniprot id: Q1RR89
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

278992:SAM23877 RS04365
gene id: 278992:SAM23877_RS04365
uniprot id: A3KJJ1
names: Similarity
messages: Belongs to the peptidase S45 family.

278992:SAM23877 RS25805
gene id: 278992:SAM23877_RS25805
uniprot id: A0A0K2AZC3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

278992:SAM23877 RS26950
gene id: 278992:SAM23877_RS26950
uniprot id: A0A0K2B0H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

278992:SAM23877 RS21050
gene id: 278992:SAM23877_RS21050
uniprot id: A0A0K2AWX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

278992:SAM23877 RS29915
gene id: 278992:SAM23877_RS29915
uniprot id: A0A0K2B244
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

278992:SAM23877 RS06215
gene id: 278992:SAM23877_RS06215
uniprot id: A3KKL2
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

278992:SAM23877 RS04950
gene id: 278992:SAM23877_RS04950
uniprot id: A3KJW0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

278992:SAM23877 RS26190
gene id: 278992:SAM23877_RS26190
uniprot id: A0A0K2B0E5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

278992:SAM23877 RS29650
gene id: 278992:SAM23877_RS29650
uniprot id: A0A0K2B2B9
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

278992:SAM23877 RS06405
gene id: 278992:SAM23877_RS06405
uniprot id: A3KKQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

278992:SAM23877 RS03705
gene id: 278992:SAM23877_RS03705
uniprot id: A3KJ61
names: Similarity
messages: Belongs to the fructosamine kinase family.

278992:SAM23877 RS17860
gene id: 278992:SAM23877_RS17860
uniprot id: A0A0K2AVG2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

278992:SAM23877 RS17760
gene id: 278992:SAM23877_RS17760
uniprot id: A0A0K2AV59
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS04795
gene id: 278992:SAM23877_RS04795
uniprot id: A3KJS8
names: Similarity
messages: Belongs to the WXG100 family.

278992:SAM23877 RS10540
gene id: 278992:SAM23877_RS10540
uniprot id: A0A0K2AQN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

278992:SAM23877 RS10370
gene id: 278992:SAM23877_RS10370
uniprot id: A0A0K2AQH6
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

278992:SAM23877 RS14070
gene id: 278992:SAM23877_RS14070
uniprot id: A0A0K2ASY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS01315
gene id: 278992:SAM23877_RS01315
uniprot id: A3KHT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS01715
gene id: 278992:SAM23877_RS01715
uniprot id: A3KI21
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS15015
gene id: 278992:SAM23877_RS15015
uniprot id: A0A0K2ATJ7
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

278992:SAM23877 RS30385
gene id: 278992:SAM23877_RS30385
uniprot id: A0A0K2B2W9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

278992:SAM23877 RS21875
gene id: 278992:SAM23877_RS21875
uniprot id: A0A0K2AXM8
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS12500
gene id: 278992:SAM23877_RS12500
uniprot id: A0A0K2ART1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

278992:SAM23877 RS03115
gene id: 278992:SAM23877_RS03115
uniprot id: A3KIU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS02665
gene id: 278992:SAM23877_RS02665
uniprot id: A3KIK2
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

278992:SAM23877 RS29400
gene id: 278992:SAM23877_RS29400
uniprot id: A0A0K2B1I5
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

278992:SAM23877 RS13320
gene id: 278992:SAM23877_RS13320
uniprot id: A0A0K2AS98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

278992:SAM23877 RS26720
gene id: 278992:SAM23877_RS26720
uniprot id: A0A0K2B0Q2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

278992:SAM23877 RS08425
gene id: 278992:SAM23877_RS08425
uniprot id: A0A0K2APF2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

278992:SAM23877 RS06845
gene id: 278992:SAM23877_RS06845
uniprot id: A3KKY5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

278992:SAM23877 RS09005
gene id: 278992:SAM23877_RS09005
uniprot id: A0A0K2APS1
names: Similarity
messages: Belongs to the CobH/CbiC family.

278992:SAM23877 RS36630
gene id: 278992:SAM23877_RS36630
uniprot id: A0A0K2B6M2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

278992:SAM23877 RS05190
gene id: 278992:SAM23877_RS05190
uniprot id: A3KK09
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

278992:SAM23877 RS26645
gene id: 278992:SAM23877_RS26645
uniprot id: A0A0K2B0N7
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

278992:SAM23877 RS33055
gene id: 278992:SAM23877_RS33055
uniprot id: A0ACX6
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS09705
gene id: 278992:SAM23877_RS09705
uniprot id: A0A0K2AQD0
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

278992:SAM23877 RS25840
gene id: 278992:SAM23877_RS25840
uniprot id: A0A0K2AZN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

278992:SAM23877 RS32020
gene id: 278992:SAM23877_RS32020
uniprot id: A0ADI5
names: Similarity
messages: Belongs to the cytochrome P450 family.

278992:SAM23877 RS15830
gene id: 278992:SAM23877_RS15830
uniprot id: A0A0K2AU20
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS21455
gene id: 278992:SAM23877_RS21455
uniprot id: A0A0K2AXM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

278992:SAM23877 RS33235
gene id: 278992:SAM23877_RS33235
uniprot id: A0ACU2
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

278992:SAM23877 RS13905
gene id: 278992:SAM23877_RS13905
uniprot id: A0A0K2AST4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

278992:SAM23877 RS04440
gene id: 278992:SAM23877_RS04440
uniprot id: A3KJK6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

278992:SAM23877 RS11990
gene id: 278992:SAM23877_RS11990
uniprot id: A0A0K2ARH5
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

278992:SAM23877 RS17705
gene id: 278992:SAM23877_RS17705
uniprot id: A0A0K2AUT8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

278992:SAM23877 RS05035
gene id: 278992:SAM23877_RS05035
uniprot id: A0A0K2AME1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

278992:SAM23877 RS20800
gene id: 278992:SAM23877_RS20800
uniprot id: A0A0K2AX83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

278992:SAM23877 RS05780
gene id: 278992:SAM23877_RS05780
uniprot id: A3KKC4
names: Biotechnology
names: Function
names: Subcellular Location Annotation
messages: Involved in the degradation of lignocellulosic biomass. Catalyzes the oxidative cleavage of glycosidic bonds in cellulosic substrates via a copper-dependent mechanism. Degrades phosphoric acid swollen cellulose (PASC) to oxidized cellooligosaccharides with degrees of polymerization of 4-8. Also shows activity on agricultural fiber paper pulps such as flax pulp. Is not active on chitin.
messages: Secreted
messages: The purification method developed for LPMOs can be a cheap, simple and fast solution for the purification of these enzymes for industrial applications. In addition, the activity of SamLPMO10C shows the potential of LPMOs in lignocellulosic biomass valorization.

278992:SAM23877 RS21130
gene id: 278992:SAM23877_RS21130
uniprot id: A0A0K2AWX4
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS22645
gene id: 278992:SAM23877_RS22645
uniprot id: A0A0K2AXQ8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

278992:SAM23877 RS16855
gene id: 278992:SAM23877_RS16855
uniprot id: A0A0K2AU17
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

278992:SAM23877 RS13050
gene id: 278992:SAM23877_RS13050
uniprot id: A0A0K2ASB6
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS26960
gene id: 278992:SAM23877_RS26960
uniprot id: A0A0K2B010
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS03490
gene id: 278992:SAM23877_RS03490
uniprot id: A3KJ16
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

278992:SAM23877 RS17410
gene id: 278992:SAM23877_RS17410
uniprot id: A0A0K2AUY5
names: Similarity
messages: Belongs to the protease inhibitor I16 (SSI) family.

278992:SAM23877 RS03185
gene id: 278992:SAM23877_RS03185
uniprot id: A3KIV5
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

278992:SAM23877 RS17425
gene id: 278992:SAM23877_RS17425
uniprot id: A0A0K2AUN0
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS14885
gene id: 278992:SAM23877_RS14885
uniprot id: A0A0K2ATA7
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS10020
gene id: 278992:SAM23877_RS10020
uniprot id: A0A0K2APZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Involved in both the histidine and tryptophan biosynthetic pathways.

278992:SAM23877 RS12360
gene id: 278992:SAM23877_RS12360
uniprot id: A0A0K2ARY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

278992:SAM23877 RS11880
gene id: 278992:SAM23877_RS11880
uniprot id: A0A0K2AR38
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

278992:SAM23877 RS06005
gene id: 278992:SAM23877_RS06005
uniprot id: A3KKH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

278992:SAM23877 RS10340
gene id: 278992:SAM23877_RS10340
uniprot id: A0A0K2AQX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

278992:SAM23877 RS21715
gene id: 278992:SAM23877_RS21715
uniprot id: A0A0K2AXD9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

278992:SAM23877 RS16685
gene id: 278992:SAM23877_RS16685
uniprot id: A0A0K2AU99
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

278992:SAM23877 RS05195
gene id: 278992:SAM23877_RS05195
uniprot id: A3KK10
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS03455
gene id: 278992:SAM23877_RS03455
uniprot id: A3KJ09
names: Similarity
messages: Belongs to the cytochrome P450 family.

278992:SAM23877 RS14180
gene id: 278992:SAM23877_RS14180
uniprot id: A0A0K2ASV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

278992:SAM23877 RS13215
gene id: 278992:SAM23877_RS13215
uniprot id: A0A0K2ASF1
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS21755
gene id: 278992:SAM23877_RS21755
uniprot id: A0A0K2AXK2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

278992:SAM23877 RS30010
gene id: 278992:SAM23877_RS30010
uniprot id: A0A0K2B266
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

278992:SAM23877 RS06000
gene id: 278992:SAM23877_RS06000
uniprot id: A3KKH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

278992:SAM23877 RS10065
gene id: 278992:SAM23877_RS10065
uniprot id: A0A0K2AQD4
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

278992:SAM23877 RS24280
gene id: 278992:SAM23877_RS24280
uniprot id: A0A0K2AZA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

278992:SAM23877 RS07175
gene id: 278992:SAM23877_RS07175
uniprot id: A0A0K2ANW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

278992:SAM23877 RS27185
gene id: 278992:SAM23877_RS27185
uniprot id: A0A0K2B0M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS21330
gene id: 278992:SAM23877_RS21330
uniprot id: A0A0K2AX48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

278992:SAM23877 RS09375
gene id: 278992:SAM23877_RS09375
uniprot id: A0A0K2AQ11
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

278992:SAM23877 RS25480
gene id: 278992:SAM23877_RS25480
uniprot id: A0A0K2AZF9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

278992:SAM23877 RS17735
gene id: 278992:SAM23877_RS17735
uniprot id: A0A0K2AUH0
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS15895
gene id: 278992:SAM23877_RS15895
uniprot id: A0A0K2ATG8
names: Subcellular Location Annotation
messages: Cell membrane

278992:SAM23877 RS18290
gene id: 278992:SAM23877_RS18290
uniprot id: A0A0K2AV56
names: Similarity
messages: Belongs to the peptidase M18 family.

278992:SAM23877 RS03785
gene id: 278992:SAM23877_RS03785
uniprot id: A3KJ76
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS02150
gene id: 278992:SAM23877_RS02150
uniprot id: A3KIA3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

278992:SAM23877 RS22030
gene id: 278992:SAM23877_RS22030
uniprot id: A0A0K2AXD2
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

278992:SAM23877 RS23940
gene id: 278992:SAM23877_RS23940
uniprot id: A0A0K2AYJ5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

278992:SAM23877 RS12390
gene id: 278992:SAM23877_RS12390
uniprot id: A0A0K2ARR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

278992:SAM23877 RS33930
gene id: 278992:SAM23877_RS33930
uniprot id: A0ACF6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

278992:SAM23877 RS10350
gene id: 278992:SAM23877_RS10350
uniprot id: A0A0K2AQJ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

278992:SAM23877 RS27585
gene id: 278992:SAM23877_RS27585
uniprot id: A0A0K2B0P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS32125
gene id: 278992:SAM23877_RS32125
uniprot id: A0ADG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted
messages: Strong inhibitor of bacterial serine proteases such as subtilisin.

278992:SAM23877 RS08950
gene id: 278992:SAM23877_RS08950
uniprot id: A0A0K2APN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

278992:SAM23877 RS24535
gene id: 278992:SAM23877_RS24535
uniprot id: A0A0K2AYK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS31625
gene id: 278992:SAM23877_RS31625
uniprot id: A0A0K2B370
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

278992:SAM23877 RS27215
gene id: 278992:SAM23877_RS27215
uniprot id: A0A0K2B0G9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

278992:SAM23877 RS11975
gene id: 278992:SAM23877_RS11975
uniprot id: A0A0K2ARQ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

278992:SAM23877 RS32930
gene id: 278992:SAM23877_RS32930
uniprot id: A0AD01
names: Similarity
messages: Belongs to the Dps family.

278992:SAM23877 RS34850
gene id: 278992:SAM23877_RS34850
uniprot id: A0ABY2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

278992:SAM23877 RS22665
gene id: 278992:SAM23877_RS22665
uniprot id: A0A0K2AXY6
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

278992:SAM23877 RS31045
gene id: 278992:SAM23877_RS31045
uniprot id: A0AE29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS19700
gene id: 278992:SAM23877_RS19700
uniprot id: A0A0K2AWK7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

278992:SAM23877 RS16000
gene id: 278992:SAM23877_RS16000
uniprot id: A0A0K2AUD5
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

278992:SAM23877 RS12010
gene id: 278992:SAM23877_RS12010
uniprot id: A0A0K2ARH7
names: Subcellular Location Annotation
messages: Cell membrane

278992:SAM23877 RS30375
gene id: 278992:SAM23877_RS30375
uniprot id: A0A0K2B236
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

278992:SAM23877 RS21055
gene id: 278992:SAM23877_RS21055
uniprot id: A0A0K2AWU2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS35000
gene id: 278992:SAM23877_RS35000
uniprot id: A0ABV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

278992:SAM23877 RS05935
gene id: 278992:SAM23877_RS05935
uniprot id: A3KKF7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

278992:SAM23877 RS25990
gene id: 278992:SAM23877_RS25990
uniprot id: A0A0K2B0A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

278992:SAM23877 RS15235
gene id: 278992:SAM23877_RS15235
uniprot id: A0A0K2ATE6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

278992:SAM23877 RS01645
gene id: 278992:SAM23877_RS01645
uniprot id: A3KI07
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS03855
gene id: 278992:SAM23877_RS03855
uniprot id: A3KJ90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

278992:SAM23877 RS18115
gene id: 278992:SAM23877_RS18115
uniprot id: A0A0K2AV24
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS35220
gene id: 278992:SAM23877_RS35220
uniprot id: Q1RQP0
names: Similarity
messages: Belongs to the cytochrome P450 family.

278992:SAM23877 RS16140
gene id: 278992:SAM23877_RS16140
uniprot id: A0A0K2ATL8
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

278992:SAM23877 RS04975
gene id: 278992:SAM23877_RS04975
uniprot id: A3KJW5
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS03495
gene id: 278992:SAM23877_RS03495
uniprot id: A3KJ17
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

278992:SAM23877 RS23580
gene id: 278992:SAM23877_RS23580
uniprot id: A0A0K2AYJ6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: Nucleus
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

278992:SAM23877 RS22515
gene id: 278992:SAM23877_RS22515
uniprot id: A0A0K2AXM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

278992:SAM23877 RS09465
gene id: 278992:SAM23877_RS09465
uniprot id: A0A0K2AQG5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

278992:SAM23877 RS29680
gene id: 278992:SAM23877_RS29680
uniprot id: A0A0K2B2I1
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

278992:SAM23877 RS05420
gene id: 278992:SAM23877_RS05420
uniprot id: A3KK53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

278992:SAM23877 RS13975
gene id: 278992:SAM23877_RS13975
uniprot id: A0A0K2ASW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

278992:SAM23877 RS01250
gene id: 278992:SAM23877_RS01250
uniprot id: Q1RR96
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

278992:SAM23877 RS12335
gene id: 278992:SAM23877_RS12335
uniprot id: A0A0K2ARB8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

278992:SAM23877 RS13275
gene id: 278992:SAM23877_RS13275
uniprot id: A0A0K2ASB4
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

278992:SAM23877 RS31165
gene id: 278992:SAM23877_RS31165
uniprot id: A0AE05
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS21990
gene id: 278992:SAM23877_RS21990
uniprot id: A0A0K2AX23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

278992:SAM23877 RS02600
gene id: 278992:SAM23877_RS02600
uniprot id: A3KIJ0
names: Similarity
messages: Belongs to the cytochrome P450 family.

278992:SAM23877 RS13195
gene id: 278992:SAM23877_RS13195
uniprot id: A0A0K2ASP6
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

278992:SAM23877 RS33470
gene id: 278992:SAM23877_RS33470
uniprot id: A0ACP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

278992:SAM23877 RS10820
gene id: 278992:SAM23877_RS10820
uniprot id: A0A0K2AQF7
names: Similarity
messages: Belongs to the glutamine synthetase family.

278992:SAM23877 RS17875
gene id: 278992:SAM23877_RS17875
uniprot id: A0A0K2AV81
names: Similarity
messages: Belongs to the ParB family.

278992:SAM23877 RS18485
gene id: 278992:SAM23877_RS18485
uniprot id: A0A0K2AVC7
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS01070
gene id: 278992:SAM23877_RS01070
uniprot id: Q1RRD7
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

278992:SAM23877 RS08860
gene id: 278992:SAM23877_RS08860
uniprot id: A0A0K2APP0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS12595
gene id: 278992:SAM23877_RS12595
uniprot id: A0A0K2ARV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

278992:SAM23877 RS01105
gene id: 278992:SAM23877_RS01105
uniprot id: Q1RRC9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

278992:SAM23877 RS14580
gene id: 278992:SAM23877_RS14580
uniprot id: A0A0K2ATJ6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

278992:SAM23877 RS18425
gene id: 278992:SAM23877_RS18425
uniprot id: A0A0K2AVJ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

278992:SAM23877 RS08940
gene id: 278992:SAM23877_RS08940
uniprot id: A0A0K2APC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

278992:SAM23877 RS26025
gene id: 278992:SAM23877_RS26025
uniprot id: A0A0K2AZU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

278992:SAM23877 RS07095
gene id: 278992:SAM23877_RS07095
uniprot id: A0A0K2ANL6
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

278992:SAM23877 RS02325
gene id: 278992:SAM23877_RS02325
uniprot id: A3KID8
names: Similarity
messages: Belongs to the DapA family.

278992:SAM23877 RS27590
gene id: 278992:SAM23877_RS27590
uniprot id: A0A0K2B0D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS02980
gene id: 278992:SAM23877_RS02980
uniprot id: A3KIR4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

278992:SAM23877 RS23035
gene id: 278992:SAM23877_RS23035
uniprot id: A0A0K2AXY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

278992:SAM23877 RS14615
gene id: 278992:SAM23877_RS14615
uniprot id: A0A0K2ATK6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

278992:SAM23877 RS31110
gene id: 278992:SAM23877_RS31110
uniprot id: A0AE16
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus membrane

278992:SAM23877 RS20830
gene id: 278992:SAM23877_RS20830
uniprot id: A0A0K2AWT0
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

278992:SAM23877 RS28280
gene id: 278992:SAM23877_RS28280
uniprot id: A0A0K2B150
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

278992:SAM23877 RS17885
gene id: 278992:SAM23877_RS17885
uniprot id: A0A0K2AV04
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

278992:SAM23877 RS24355
gene id: 278992:SAM23877_RS24355
uniprot id: A0A0K2AYY8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

278992:SAM23877 RS19600
gene id: 278992:SAM23877_RS19600
uniprot id: A0A0K2AWI7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

278992:SAM23877 RS06195
gene id: 278992:SAM23877_RS06195
uniprot id: A0A0K2ANB5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS31645
gene id: 278992:SAM23877_RS31645
uniprot id: A0ADQ9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

278992:SAM23877 RS13865
gene id: 278992:SAM23877_RS13865
uniprot id: A0A0K2ASN4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

278992:SAM23877 RS34955
gene id: 278992:SAM23877_RS34955
uniprot id: A0ABW3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

278992:SAM23877 RS32265
gene id: 278992:SAM23877_RS32265
uniprot id: A0ADD6
names: Similarity
messages: Belongs to the peptidase S1 family.

278992:SAM23877 RS21340
gene id: 278992:SAM23877_RS21340
uniprot id: A0A0K2AWQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

278992:SAM23877 RS16065
gene id: 278992:SAM23877_RS16065
uniprot id: A0A0K2ATK3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

278992:SAM23877 RS18320
gene id: 278992:SAM23877_RS18320
uniprot id: A0A0K2AUU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS06160
gene id: 278992:SAM23877_RS06160
uniprot id: A3KKK1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

278992:SAM23877 RS03985
gene id: 278992:SAM23877_RS03985
uniprot id: A3KJB5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

278992:SAM23877 RS21485
gene id: 278992:SAM23877_RS21485
uniprot id: A0A0K2AX76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

278992:SAM23877 RS20415
gene id: 278992:SAM23877_RS20415
uniprot id: A0A0K2AWS1
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS09965
gene id: 278992:SAM23877_RS09965
uniprot id: A0A0K2AQ93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

278992:SAM23877 RS06020
gene id: 278992:SAM23877_RS06020
uniprot id: A3KKH4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

278992:SAM23877 RS06695
gene id: 278992:SAM23877_RS06695
uniprot id: A3KKV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

278992:SAM23877 RS13935
gene id: 278992:SAM23877_RS13935
uniprot id: A0A0K2ASP9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

278992:SAM23877 RS14285
gene id: 278992:SAM23877_RS14285
uniprot id: A0A0K2ASY3
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

278992:SAM23877 RS22715
gene id: 278992:SAM23877_RS22715
uniprot id: A0A0K2AXZ7
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS15075
gene id: 278992:SAM23877_RS15075
uniprot id: A0A0K2ATB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

278992:SAM23877 RS07125
gene id: 278992:SAM23877_RS07125
uniprot id: A0A0K2AND0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS13790
gene id: 278992:SAM23877_RS13790
uniprot id: A0A0K2ASM1
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS01920
gene id: 278992:SAM23877_RS01920
uniprot id: A0A0K2AKB8
names: Similarity
messages: Belongs to the peptidase S33 family.

278992:SAM23877 RS09275
gene id: 278992:SAM23877_RS09275
uniprot id: A0A0K2APZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

278992:SAM23877 RS06415
gene id: 278992:SAM23877_RS06415
uniprot id: A3KKQ3
names: Similarity
messages: Belongs to the 3-hydroxybenzoate 6-hydroxylase family.

278992:SAM23877 RS30120
gene id: 278992:SAM23877_RS30120
uniprot id: A0A0K2B2L0
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS25940
gene id: 278992:SAM23877_RS25940
uniprot id: A0A0K2B079
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

278992:SAM23877 RS23810
gene id: 278992:SAM23877_RS23810
uniprot id: A0A0K2AYU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS34100
gene id: 278992:SAM23877_RS34100
uniprot id: A0ACC2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

278992:SAM23877 RS08985
gene id: 278992:SAM23877_RS08985
uniprot id: A0A0K2APD9
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS10900
gene id: 278992:SAM23877_RS10900
uniprot id: A0A0K2AR14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS08480
gene id: 278992:SAM23877_RS08480
uniprot id: A0A0K2AP26
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

278992:SAM23877 RS13010
gene id: 278992:SAM23877_RS13010
uniprot id: A0A0K2ASA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

278992:SAM23877 RS07685
gene id: 278992:SAM23877_RS07685
uniprot id: A0A0K2ANZ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

278992:SAM23877 RS14515
gene id: 278992:SAM23877_RS14515
uniprot id: A0A0K2AT31
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2-dependent reduction of dehydro-F420-0 to form F420-0.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: In the N-terminal section; belongs to the CofE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monovalent cation. The ion could be potassium.

278992:SAM23877 RS31050
gene id: 278992:SAM23877_RS31050
uniprot id: A0AE28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS33640
gene id: 278992:SAM23877_RS33640
uniprot id: A0ACL3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

278992:SAM23877 RS16590
gene id: 278992:SAM23877_RS16590
uniprot id: A0A0K2ATW9
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

278992:SAM23877 RS29685
gene id: 278992:SAM23877_RS29685
uniprot id: A0A0K2B270
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

278992:SAM23877 RS17840
gene id: 278992:SAM23877_RS17840
uniprot id: A0A0K2AUZ3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS33325
gene id: 278992:SAM23877_RS33325
uniprot id: A0ACS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

278992:SAM23877 RS08230
gene id: 278992:SAM23877_RS08230
uniprot id: A0A0K2APP3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS12420
gene id: 278992:SAM23877_RS12420
uniprot id: A0A0K2ARD9
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

278992:SAM23877 RS31445
gene id: 278992:SAM23877_RS31445
uniprot id: A0ADU9
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

278992:SAM23877 RS33630
gene id: 278992:SAM23877_RS33630
uniprot id: A0ACL5
names: Similarity
messages: Belongs to the DNA photolyase family.

278992:SAM23877 RS05820
gene id: 278992:SAM23877_RS05820
uniprot id: A3KKD2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

278992:SAM23877 RS29525
gene id: 278992:SAM23877_RS29525
uniprot id: A0A0K2B298
names: Similarity
messages: Belongs to the TPP enzyme family.

278992:SAM23877 RS28380
gene id: 278992:SAM23877_RS28380
uniprot id: A0A0K2B185
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

278992:SAM23877 RS16760
gene id: 278992:SAM23877_RS16760
uniprot id: A0A0K2AUB4
names: Similarity
messages: Belongs to the CsoR family.

278992:SAM23877 RS30525
gene id: 278992:SAM23877_RS30525
uniprot id: A0A0K2B2Z8
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

278992:SAM23877 RS23095
gene id: 278992:SAM23877_RS23095
uniprot id: A0A0K2AYC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS15135
gene id: 278992:SAM23877_RS15135
uniprot id: A0A0K2ATM2
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS23845
gene id: 278992:SAM23877_RS23845
uniprot id: A0A0K2AYH8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

278992:SAM23877 RS11580
gene id: 278992:SAM23877_RS11580
uniprot id: A0A0K2AQZ0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

278992:SAM23877 RS00970
gene id: 278992:SAM23877_RS00970
uniprot id: Q1RRF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS04660
gene id: 278992:SAM23877_RS04660
uniprot id: A0A0K2AM72
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS33380
gene id: 278992:SAM23877_RS33380
uniprot id: A0ACR3
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

278992:SAM23877 RS22480
gene id: 278992:SAM23877_RS22480
uniprot id: A0A0K2AY76
names: Similarity
messages: Belongs to the phosphohexose mutase family.

278992:SAM23877 RS34990
gene id: 278992:SAM23877_RS34990
uniprot id: A0ABV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

278992:SAM23877 RS24530
gene id: 278992:SAM23877_RS24530
uniprot id: A0A0K2AYW0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

278992:SAM23877 RS32955
gene id: 278992:SAM23877_RS32955
uniprot id: A0ACZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

278992:SAM23877 RS21385
gene id: 278992:SAM23877_RS21385
uniprot id: A0A0K2AX15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

278992:SAM23877 RS08380
gene id: 278992:SAM23877_RS08380
uniprot id: A0A0K2APB8
names: Similarity
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.

278992:SAM23877 RS03365
gene id: 278992:SAM23877_RS03365
uniprot id: A3KIZ1
names: Similarity
messages: Belongs to the TPP enzyme family.

278992:SAM23877 RS24230
gene id: 278992:SAM23877_RS24230
uniprot id: A0A0K2AZ21
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

278992:SAM23877 RS09195
gene id: 278992:SAM23877_RS09195
uniprot id: A0A0K2APV5
names: Similarity
messages: Belongs to the DapA family.

278992:SAM23877 RS09385
gene id: 278992:SAM23877_RS09385
uniprot id: A0A0K2AQ75
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS19060
gene id: 278992:SAM23877_RS19060
uniprot id: A0A0K2AVM5
names: Similarity
messages: Belongs to the CdaR family.

278992:SAM23877 RS05150
gene id: 278992:SAM23877_RS05150
uniprot id: A3KK00
names: Similarity
messages: Belongs to the Dps family.

278992:SAM23877 RS24600
gene id: 278992:SAM23877_RS24600
uniprot id: A0A0K2AZ34
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

278992:SAM23877 RS08195
gene id: 278992:SAM23877_RS08195
uniprot id: A0A0K2ANX0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

278992:SAM23877 RS27770
gene id: 278992:SAM23877_RS27770
uniprot id: A0A0K2B1A3
names: Subcellular Location Annotation
messages: COPI-coated vesicle membrane

278992:SAM23877 RS25405
gene id: 278992:SAM23877_RS25405
uniprot id: A0A0K2AZE7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

278992:SAM23877 RS14225
gene id: 278992:SAM23877_RS14225
uniprot id: A0A0K2ASI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS31420
gene id: 278992:SAM23877_RS31420
uniprot id: A0ADV4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

278992:SAM23877 RS07155
gene id: 278992:SAM23877_RS07155
uniprot id: A0A0K2AP40
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

278992:SAM23877 RS14715
gene id: 278992:SAM23877_RS14715
uniprot id: A0A0K2ATM7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

278992:SAM23877 RS17055
gene id: 278992:SAM23877_RS17055
uniprot id: A0A0K2AUS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

278992:SAM23877 RS07975
gene id: 278992:SAM23877_RS07975
uniprot id: A0A0K2AP56
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS11000
gene id: 278992:SAM23877_RS11000
uniprot id: A0A0K2ARD2
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

278992:SAM23877 RS24895
gene id: 278992:SAM23877_RS24895
uniprot id: A0A0K2AZ41
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

278992:SAM23877 RS06055
gene id: 278992:SAM23877_RS06055
uniprot id: A3KKI1
names: Similarity
messages: Belongs to the peptidase C40 family.

278992:SAM23877 RS17865
gene id: 278992:SAM23877_RS17865
uniprot id: A0A0K2AUZ9
names: Similarity
messages: Belongs to the thioredoxin family.

278992:SAM23877 RS25665
gene id: 278992:SAM23877_RS25665
uniprot id: A0A0K2AZW5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

278992:SAM23877 RS33125
gene id: 278992:SAM23877_RS33125
uniprot id: A0ACW3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

278992:SAM23877 RS12525
gene id: 278992:SAM23877_RS12525
uniprot id: A0A0K2ARG1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

278992:SAM23877 RS24775
gene id: 278992:SAM23877_RS24775
uniprot id: A0A0K2AZ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

278992:SAM23877 RS30905
gene id: 278992:SAM23877_RS30905
uniprot id: A0AE57
names: Similarity
messages: Belongs to the TPP enzyme family.

278992:SAM23877 RS20635
gene id: 278992:SAM23877_RS20635
uniprot id: A0A0K2AWX0
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS14545
gene id: 278992:SAM23877_RS14545
uniprot id: A0A0K2AT10
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

278992:SAM23877 RS32690
gene id: 278992:SAM23877_RS32690
uniprot id: A0AD49
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

278992:SAM23877 RS05535
gene id: 278992:SAM23877_RS05535
uniprot id: A0A0K2AMP0
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

278992:SAM23877 RS30660
gene id: 278992:SAM23877_RS30660
uniprot id: A0AEA4
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS22940
gene id: 278992:SAM23877_RS22940
uniprot id: A0A0K2AXL5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS24290
gene id: 278992:SAM23877_RS24290
uniprot id: A0A0K2AYR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

278992:SAM23877 RS14470
gene id: 278992:SAM23877_RS14470
uniprot id: A0A0K2AT21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

278992:SAM23877 RS30170
gene id: 278992:SAM23877_RS30170
uniprot id: A0A0K2B2S4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

278992:SAM23877 RS07980
gene id: 278992:SAM23877_RS07980
uniprot id: A0A0K2ANS9
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

278992:SAM23877 RS15335
gene id: 278992:SAM23877_RS15335
uniprot id: A0A0K2ATZ8
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS03385
gene id: 278992:SAM23877_RS03385
uniprot id: A3KIZ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS10165
gene id: 278992:SAM23877_RS10165
uniprot id: A0A0K2AQU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

278992:SAM23877 RS24215
gene id: 278992:SAM23877_RS24215
uniprot id: A0A0K2AYW2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

278992:SAM23877 RS33525
gene id: 278992:SAM23877_RS33525
uniprot id: A0ACN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS11565
gene id: 278992:SAM23877_RS11565
uniprot id: A0A0K2ART5
names: Similarity
messages: Belongs to the fabD family.

278992:SAM23877 RS30380
gene id: 278992:SAM23877_RS30380
uniprot id: A0A0K2B2R9
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS10530
gene id: 278992:SAM23877_RS10530
uniprot id: A0A0K2AR41
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS20775
gene id: 278992:SAM23877_RS20775
uniprot id: A0A0K2AX77
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

278992:SAM23877 RS20115
gene id: 278992:SAM23877_RS20115
uniprot id: A0A0K2AWT5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

278992:SAM23877 RS16050
gene id: 278992:SAM23877_RS16050
uniprot id: A0A0K2AUE4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

278992:SAM23877 RS16865
gene id: 278992:SAM23877_RS16865
uniprot id: A0A0K2AUY1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS14690
gene id: 278992:SAM23877_RS14690
uniprot id: A0A0K2ATM1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

278992:SAM23877 RS05715
gene id: 278992:SAM23877_RS05715
uniprot id: A3KKB2
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

278992:SAM23877 RS27610
gene id: 278992:SAM23877_RS27610
uniprot id: A0A0K2B0E3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS28740
gene id: 278992:SAM23877_RS28740
uniprot id: A0A0K2B1T2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

278992:SAM23877 RS18270
gene id: 278992:SAM23877_RS18270
uniprot id: A0A0K2AUT6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

278992:SAM23877 RS12665
gene id: 278992:SAM23877_RS12665
uniprot id: A0A0K2ASD9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS30410
gene id: 278992:SAM23877_RS30410
uniprot id: A0A0K2B2X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS15020
gene id: 278992:SAM23877_RS15020
uniprot id: A0A0K2ATD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

278992:SAM23877 RS28065
gene id: 278992:SAM23877_RS28065
uniprot id: A0A0K2B1C7
names: Similarity
messages: Belongs to the NodU/CmcH family.

278992:SAM23877 RS12365
gene id: 278992:SAM23877_RS12365
uniprot id: A0A0K2AS84
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

278992:SAM23877 RS19675
gene id: 278992:SAM23877_RS19675
uniprot id: A0A0K2AWK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

278992:SAM23877 RS09330
gene id: 278992:SAM23877_RS09330
uniprot id: A0A0K2APM8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

278992:SAM23877 RS07740
gene id: 278992:SAM23877_RS07740
uniprot id: A0A0K2ANN5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

278992:SAM23877 RS14755
gene id: 278992:SAM23877_RS14755
uniprot id: A0A0K2ASS5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

278992:SAM23877 RS23815
gene id: 278992:SAM23877_RS23815
uniprot id: A0A0K2AZ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS00860
gene id: 278992:SAM23877_RS00860
uniprot id: Q1RQQ6
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

278992:SAM23877 RS18610
gene id: 278992:SAM23877_RS18610
uniprot id: A0A0K2AVN1
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS07590
gene id: 278992:SAM23877_RS07590
uniprot id: A0A0K2ANX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

278992:SAM23877 RS23310
gene id: 278992:SAM23877_RS23310
uniprot id: A0A0K2AYG8
names: Similarity
messages: Belongs to the UPF0162 family.

278992:SAM23877 RS26940
gene id: 278992:SAM23877_RS26940
uniprot id: A0A0K2B0P4
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS10975
gene id: 278992:SAM23877_RS10975
uniprot id: A0A0K2ARC6
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS17645
gene id: 278992:SAM23877_RS17645
uniprot id: A0A0K2AV36
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

278992:SAM23877 RS21070
gene id: 278992:SAM23877_RS21070
uniprot id: A0A0K2AXD6
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS30635
gene id: 278992:SAM23877_RS30635
uniprot id: A0AEA9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

278992:SAM23877 RS19730
gene id: 278992:SAM23877_RS19730
uniprot id: A0A0K2AW46
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

278992:SAM23877 RS31280
gene id: 278992:SAM23877_RS31280
uniprot id: A0ADY3
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

278992:SAM23877 RS15750
gene id: 278992:SAM23877_RS15750
uniprot id: A0A0K2ATQ4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

278992:SAM23877 RS19020
gene id: 278992:SAM23877_RS19020
uniprot id: A0A0K2AVA9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS10550
gene id: 278992:SAM23877_RS10550
uniprot id: A0A0K2AQV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS19815
gene id: 278992:SAM23877_RS19815
uniprot id: A0A0K2AVR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

278992:SAM23877 RS19770
gene id: 278992:SAM23877_RS19770
uniprot id: A0A0K2AWD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

278992:SAM23877 RS07575
gene id: 278992:SAM23877_RS07575
uniprot id: A0A0K2AP42
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

278992:SAM23877 RS00675
gene id: 278992:SAM23877_RS00675
uniprot id: Q1RQU3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS31080
gene id: 278992:SAM23877_RS31080
uniprot id: A0AE22
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS25355
gene id: 278992:SAM23877_RS25355
uniprot id: A0A0K2AZD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS15835
gene id: 278992:SAM23877_RS15835
uniprot id: A0A0K2AUA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS06275
gene id: 278992:SAM23877_RS06275
uniprot id: A3KKM4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

278992:SAM23877 RS24190
gene id: 278992:SAM23877_RS24190
uniprot id: A0A0K2AYV7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

278992:SAM23877 RS23265
gene id: 278992:SAM23877_RS23265
uniprot id: A0A0K2AYN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS03360
gene id: 278992:SAM23877_RS03360
uniprot id: A3KIZ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS07480
gene id: 278992:SAM23877_RS07480
uniprot id: A0A0K2AP99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS02920
gene id: 278992:SAM23877_RS02920
uniprot id: A3KIQ2
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS13440
gene id: 278992:SAM23877_RS13440
uniprot id: A0A0K2ASU3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

278992:SAM23877 RS22225
gene id: 278992:SAM23877_RS22225
uniprot id: A0A0K2AXG9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS31515
gene id: 278992:SAM23877_RS31515
uniprot id: A0ADT5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

278992:SAM23877 RS15010
gene id: 278992:SAM23877_RS15010
uniprot id: A0A0K2ASY0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

278992:SAM23877 RS06035
gene id: 278992:SAM23877_RS06035
uniprot id: A3KKH7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

278992:SAM23877 RS08415
gene id: 278992:SAM23877_RS08415
uniprot id: A0A0K2APT0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

278992:SAM23877 RS17710
gene id: 278992:SAM23877_RS17710
uniprot id: A0A0K2AUG5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

278992:SAM23877 RS33960
gene id: 278992:SAM23877_RS33960
uniprot id: A0ACF0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

278992:SAM23877 RS21025
gene id: 278992:SAM23877_RS21025
uniprot id: A0A0K2AWW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

278992:SAM23877 RS03375
gene id: 278992:SAM23877_RS03375
uniprot id: A3KIZ3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS22925
gene id: 278992:SAM23877_RS22925
uniprot id: A0A0K2AYG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

278992:SAM23877 RS09445
gene id: 278992:SAM23877_RS09445
uniprot id: A0A0K2APZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

278992:SAM23877 RS30150
gene id: 278992:SAM23877_RS30150
uniprot id: A0A0K2B2F8
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

278992:SAM23877 RS21745
gene id: 278992:SAM23877_RS21745
uniprot id: A0A0K2AX82
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

278992:SAM23877 RS27340
gene id: 278992:SAM23877_RS27340
uniprot id: A0A0K2B088
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

278992:SAM23877 RS25395
gene id: 278992:SAM23877_RS25395
uniprot id: A0A0K2AZW9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

278992:SAM23877 RS26600
gene id: 278992:SAM23877_RS26600
uniprot id: A0A0K2B0A2
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

278992:SAM23877 RS21360
gene id: 278992:SAM23877_RS21360
uniprot id: A0A0K2AX11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

278992:SAM23877 RS26780
gene id: 278992:SAM23877_RS26780
uniprot id: A0A0K2B0L2
names: Similarity
messages: Belongs to the cytochrome P450 family.

278992:SAM23877 RS23695
gene id: 278992:SAM23877_RS23695
uniprot id: A0A0K2AYL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS20085
gene id: 278992:SAM23877_RS20085
uniprot id: A0A0K2AWK5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS10360
gene id: 278992:SAM23877_RS10360
uniprot id: A0A0K2AQR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

278992:SAM23877 RS08465
gene id: 278992:SAM23877_RS08465
uniprot id: A0A0K2APT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

278992:SAM23877 RS11915
gene id: 278992:SAM23877_RS11915
uniprot id: A0A0K2ARG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

278992:SAM23877 RS31615
gene id: 278992:SAM23877_RS31615
uniprot id: A0ADR5
names: Similarity
messages: Belongs to the creatininase superfamily.

278992:SAM23877 RS03260
gene id: 278992:SAM23877_RS03260
uniprot id: A3KIW9
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS29425
gene id: 278992:SAM23877_RS29425
uniprot id: A0A0K2B1I9
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

278992:SAM23877 RS18065
gene id: 278992:SAM23877_RS18065
uniprot id: A0A0K2AUP6
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS28765
gene id: 278992:SAM23877_RS28765
uniprot id: A0A0K2B1T7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

278992:SAM23877 RS33945
gene id: 278992:SAM23877_RS33945
uniprot id: A0ACF3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

278992:SAM23877 RS21355
gene id: 278992:SAM23877_RS21355
uniprot id: A0A0K2AX53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

278992:SAM23877 RS23245
gene id: 278992:SAM23877_RS23245
uniprot id: A0A0K2AYA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS04675
gene id: 278992:SAM23877_RS04675
uniprot id: A3KJQ3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS23750
gene id: 278992:SAM23877_RS23750
uniprot id: A0A0K2AYG1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

278992:SAM23877 RS31650
gene id: 278992:SAM23877_RS31650
uniprot id: A0ADQ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

278992:SAM23877 RS19430
gene id: 278992:SAM23877_RS19430
uniprot id: A0A0K2AW68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Membrane

278992:SAM23877 RS14155
gene id: 278992:SAM23877_RS14155
uniprot id: A0A0K2ASV6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS25845
gene id: 278992:SAM23877_RS25845
uniprot id: A0A0K2AZD3
names: Similarity
messages: Belongs to the peptidase M16 family.

278992:SAM23877 RS28800
gene id: 278992:SAM23877_RS28800
uniprot id: A0A0K2B1N0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

278992:SAM23877 RS09815
gene id: 278992:SAM23877_RS09815
uniprot id: A0A0K2AQ66
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS14095
gene id: 278992:SAM23877_RS14095
uniprot id: A0A0K2ASY9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

278992:SAM23877 RS34210
gene id: 278992:SAM23877_RS34210
uniprot id: A0ACA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS32425
gene id: 278992:SAM23877_RS32425
uniprot id: A0ADA4
names: Similarity
messages: Belongs to the CdaR family.

278992:SAM23877 RS10305
gene id: 278992:SAM23877_RS10305
uniprot id: A0A0K2AQ53
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

278992:SAM23877 RS20770
gene id: 278992:SAM23877_RS20770
uniprot id: A0A0K2AX00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

278992:SAM23877 RS25655
gene id: 278992:SAM23877_RS25655
uniprot id: A0A0K2AZJ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

278992:SAM23877 RS31570
gene id: 278992:SAM23877_RS31570
uniprot id: A0ADS4
names: Similarity
messages: Belongs to the pirin family.

278992:SAM23877 RS10425
gene id: 278992:SAM23877_RS10425
uniprot id: A0A0K2AQT3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

278992:SAM23877 RS15510
gene id: 278992:SAM23877_RS15510
uniprot id: A0A0K2ATM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

278992:SAM23877 RS07090
gene id: 278992:SAM23877_RS07090
uniprot id: A0A0K2ANM1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

278992:SAM23877 RS10925
gene id: 278992:SAM23877_RS10925
uniprot id: A0A0K2ARB6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

278992:SAM23877 RS14360
gene id: 278992:SAM23877_RS14360
uniprot id: A0A0K2AT44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

278992:SAM23877 RS05385
gene id: 278992:SAM23877_RS05385
uniprot id: A0A0K2AML0
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

278992:SAM23877 RS33020
gene id: 278992:SAM23877_RS33020
uniprot id: A0ACY3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

278992:SAM23877 RS10575
gene id: 278992:SAM23877_RS10575
uniprot id: A0A0K2AQW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

278992:SAM23877 RS09155
gene id: 278992:SAM23877_RS09155
uniprot id: A0A0K2APK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS29695
gene id: 278992:SAM23877_RS29695
uniprot id: A0A0K2B2C9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

278992:SAM23877 RS04680
gene id: 278992:SAM23877_RS04680
uniprot id: A3KJQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

278992:SAM23877 RS07680
gene id: 278992:SAM23877_RS07680
uniprot id: A0A0K2ANX4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

278992:SAM23877 RS08690
gene id: 278992:SAM23877_RS08690
uniprot id: A0A0K2API0
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS29975
gene id: 278992:SAM23877_RS29975
uniprot id: A0A0K2B2N7
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

278992:SAM23877 RS04350
gene id: 278992:SAM23877_RS04350
uniprot id: A3KJI8
names: Similarity
messages: Belongs to the universal stress protein A family.

278992:SAM23877 RS16715
gene id: 278992:SAM23877_RS16715
uniprot id: A0A0K2ATZ0
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

278992:SAM23877 RS20845
gene id: 278992:SAM23877_RS20845
uniprot id: A0A0K2AX13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS16135
gene id: 278992:SAM23877_RS16135
uniprot id: A0A0K2ATY7
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

278992:SAM23877 RS06805
gene id: 278992:SAM23877_RS06805
uniprot id: A3KKX7
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS06660
gene id: 278992:SAM23877_RS06660
uniprot id: A3KKU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

278992:SAM23877 RS19715
gene id: 278992:SAM23877_RS19715
uniprot id: A0A0K2AVP2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

278992:SAM23877 RS02590
gene id: 278992:SAM23877_RS02590
uniprot id: A3KII8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS35730
gene id: 278992:SAM23877_RS35730
uniprot id: Q1RQZ4
names: Subcellular Location Annotation
messages: Cytoplasm

278992:SAM23877 RS06580
gene id: 278992:SAM23877_RS06580
uniprot id: A3KKT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

278992:SAM23877 RS00235
gene id: 278992:SAM23877_RS00235
uniprot id: Q1RR37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

278992:SAM23877 RS22335
gene id: 278992:SAM23877_RS22335
uniprot id: A0A0K2AXW8
names: Similarity
messages: Belongs to the BMP lipoprotein family.

278992:SAM23877 RS15250
gene id: 278992:SAM23877_RS15250
uniprot id: A0A0K2ATF3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

278992:SAM23877 RS01800
gene id: 278992:SAM23877_RS01800
uniprot id: A3KI37
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS14680
gene id: 278992:SAM23877_RS14680
uniprot id: A0A0K2ASR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

278992:SAM23877 RS19775
gene id: 278992:SAM23877_RS19775
uniprot id: A0A0K2AWL7
names: Subcellular Location Annotation
messages: Mitochondrion

278992:SAM23877 RS14135
gene id: 278992:SAM23877_RS14135
uniprot id: A0A0K2ASS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS09595
gene id: 278992:SAM23877_RS09595
uniprot id: A0A0K2AQ23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

278992:SAM23877 RS17630
gene id: 278992:SAM23877_RS17630
uniprot id: A0A0K2AUU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

278992:SAM23877 RS31335
gene id: 278992:SAM23877_RS31335
uniprot id: A0ADX2
names: Similarity
messages: Belongs to the universal stress protein A family.

278992:SAM23877 RS30155
gene id: 278992:SAM23877_RS30155
uniprot id: A0A0K2B295
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

278992:SAM23877 RS25530
gene id: 278992:SAM23877_RS25530
uniprot id: A0A0K2AZG7
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

278992:SAM23877 RS33110
gene id: 278992:SAM23877_RS33110
uniprot id: A0ACW6
names: Subcellular Location Annotation
messages: Cell membrane

278992:SAM23877 RS16935
gene id: 278992:SAM23877_RS16935
uniprot id: A0A0K2AUE2
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS02815
gene id: 278992:SAM23877_RS02815
uniprot id: A3KIN1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS33780
gene id: 278992:SAM23877_RS33780
uniprot id: A0ACI4
names: Similarity
messages: Belongs to the cytochrome P450 family.

278992:SAM23877 RS01890
gene id: 278992:SAM23877_RS01890
uniprot id: A3KI55
names: Subcellular Location Annotation
messages: Cytoplasm

278992:SAM23877 RS03675
gene id: 278992:SAM23877_RS03675
uniprot id: A3KJ55
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS15630
gene id: 278992:SAM23877_RS15630
uniprot id: A0A0K2ATQ3
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

278992:SAM23877 RS26500
gene id: 278992:SAM23877_RS26500
uniprot id: A0A0K2B085
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS24415
gene id: 278992:SAM23877_RS24415
uniprot id: A0A0K2AYI2
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

278992:SAM23877 RS29145
gene id: 278992:SAM23877_RS29145
uniprot id: A0A0K2B272
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

278992:SAM23877 RS30060
gene id: 278992:SAM23877_RS30060
uniprot id: A0A0K2B276
names: Similarity
messages: Belongs to the DapA family.

278992:SAM23877 RS00790
gene id: 278992:SAM23877_RS00790
uniprot id: Q1RQS0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

278992:SAM23877 RS12435
gene id: 278992:SAM23877_RS12435
uniprot id: A0A0K2ARR9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

278992:SAM23877 RS06235
gene id: 278992:SAM23877_RS06235
uniprot id: A3KKL6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

278992:SAM23877 RS26920
gene id: 278992:SAM23877_RS26920
uniprot id: A0A0K2B000
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS11890
gene id: 278992:SAM23877_RS11890
uniprot id: A0A0K2ARZ2
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

278992:SAM23877 RS08905
gene id: 278992:SAM23877_RS08905
uniprot id: A0A0K2APM5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

278992:SAM23877 RS18805
gene id: 278992:SAM23877_RS18805
uniprot id: A0A0K2AV70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

278992:SAM23877 RS06360
gene id: 278992:SAM23877_RS06360
uniprot id: A0A0K2AN55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS04875
gene id: 278992:SAM23877_RS04875
uniprot id: A3KJU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS11030
gene id: 278992:SAM23877_RS11030
uniprot id: A0A0K2AQX3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

278992:SAM23877 RS07085
gene id: 278992:SAM23877_RS07085
uniprot id: A0A0K2AP25
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS26380
gene id: 278992:SAM23877_RS26380
uniprot id: A0A0K2B0D1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS14950
gene id: 278992:SAM23877_RS14950
uniprot id: A0A0K2ATS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

278992:SAM23877 RS13520
gene id: 278992:SAM23877_RS13520
uniprot id: A0A0K2ASG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

278992:SAM23877 RS38210
gene id: 278992:SAM23877_RS38210
uniprot id: A0AD69
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

278992:SAM23877 RS35920
gene id: 278992:SAM23877_RS35920
uniprot id: Q1RR38
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

278992:SAM23877 RS05720
gene id: 278992:SAM23877_RS05720
uniprot id: A3KKB3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

278992:SAM23877 RS10180
gene id: 278992:SAM23877_RS10180
uniprot id: A0A0K2AQ28
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

278992:SAM23877 RS17680
gene id: 278992:SAM23877_RS17680
uniprot id: A0A0K2AUT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

278992:SAM23877 RS24330
gene id: 278992:SAM23877_RS24330
uniprot id: A0A0K2AZB4
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

278992:SAM23877 RS21425
gene id: 278992:SAM23877_RS21425
uniprot id: A0A0K2AXM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

278992:SAM23877 RS14670
gene id: 278992:SAM23877_RS14670
uniprot id: A0A0K2AT64
names: Subcellular Location Annotation
messages: Cell membrane

278992:SAM23877 RS07540
gene id: 278992:SAM23877_RS07540
uniprot id: A0A0K2ANW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

278992:SAM23877 RS02020
gene id: 278992:SAM23877_RS02020
uniprot id: A3KI79
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

278992:SAM23877 RS11815
gene id: 278992:SAM23877_RS11815
uniprot id: A0A0K2ARE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS33765
gene id: 278992:SAM23877_RS33765
uniprot id: A0ACI7
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

278992:SAM23877 RS24475
gene id: 278992:SAM23877_RS24475
uniprot id: A0A0K2AZ12
names: Similarity
messages: Belongs to the UPF0045 family.

278992:SAM23877 RS32100
gene id: 278992:SAM23877_RS32100
uniprot id: A0ADG9
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

278992:SAM23877 RS26335
gene id: 278992:SAM23877_RS26335
uniprot id: A0A0K2B0C1
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

278992:SAM23877 RS33595
gene id: 278992:SAM23877_RS33595
uniprot id: A0ACM1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS33000
gene id: 278992:SAM23877_RS33000
uniprot id: A0ACY7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

278992:SAM23877 RS06075
gene id: 278992:SAM23877_RS06075
uniprot id: A3KKI6
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

278992:SAM23877 RS34425
gene id: 278992:SAM23877_RS34425
uniprot id: A0AC59
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

278992:SAM23877 RS16115
gene id: 278992:SAM23877_RS16115
uniprot id: A0A0K2ATL3
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

278992:SAM23877 RS12585
gene id: 278992:SAM23877_RS12585
uniprot id: A0A0K2AS31
names: Similarity
messages: Belongs to the LacAB/RpiB family.

278992:SAM23877 RS01725
gene id: 278992:SAM23877_RS01725
uniprot id: A3KI23
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS10390
gene id: 278992:SAM23877_RS10390
uniprot id: A0A0K2AQK3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

278992:SAM23877 RS03860
gene id: 278992:SAM23877_RS03860
uniprot id: A3KJ91
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

278992:SAM23877 RS03040
gene id: 278992:SAM23877_RS03040
uniprot id: A3KIS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS24730
gene id: 278992:SAM23877_RS24730
uniprot id: A0A0K2AZ04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

278992:SAM23877 RS00855
gene id: 278992:SAM23877_RS00855
uniprot id: Q1RQQ7
names: Similarity
messages: Belongs to the thioesterase family.

278992:SAM23877 RS12690
gene id: 278992:SAM23877_RS12690
uniprot id: A0A0K2ASE4
names: Similarity
messages: Belongs to the disproportionating enzyme family.

278992:SAM23877 RS24485
gene id: 278992:SAM23877_RS24485
uniprot id: A0A0K2AYJ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS35915
gene id: 278992:SAM23877_RS35915
uniprot id: Q1RR37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

278992:SAM23877 RS31230
gene id: 278992:SAM23877_RS31230
uniprot id: A0ADZ4
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

278992:SAM23877 RS08715
gene id: 278992:SAM23877_RS08715
uniprot id: A0A0K2API4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

278992:SAM23877 RS33240
gene id: 278992:SAM23877_RS33240
uniprot id: A0ACU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS32225
gene id: 278992:SAM23877_RS32225
uniprot id: A0ADE4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

278992:SAM23877 RS07075
gene id: 278992:SAM23877_RS07075
uniprot id: A0A0K2ANC4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

278992:SAM23877 RS02740
gene id: 278992:SAM23877_RS02740
uniprot id: A3KIL6
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS32520
gene id: 278992:SAM23877_RS32520
uniprot id: A0AD85
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS04155
gene id: 278992:SAM23877_RS04155
uniprot id: A3KJE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS31285
gene id: 278992:SAM23877_RS31285
uniprot id: A0A0K2B343
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS11870
gene id: 278992:SAM23877_RS11870
uniprot id: A0A0K2ARF4
names: Similarity
messages: Belongs to the universal stress protein A family.

278992:SAM23877 RS07345
gene id: 278992:SAM23877_RS07345
uniprot id: A0A0K2ANT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS09310
gene id: 278992:SAM23877_RS09310
uniprot id: A0A0K2AQ60
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

278992:SAM23877 RS33830
gene id: 278992:SAM23877_RS33830
uniprot id: A0ACH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS05860
gene id: 278992:SAM23877_RS05860
uniprot id: A3KKE1
names: Similarity
messages: Belongs to the cytochrome P450 family.

278992:SAM23877 RS04215
gene id: 278992:SAM23877_RS04215
uniprot id: A3KJG1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS05525
gene id: 278992:SAM23877_RS05525
uniprot id: A3KK74
names: Subcellular Location Annotation
messages: Cytoplasm

278992:SAM23877 RS30310
gene id: 278992:SAM23877_RS30310
uniprot id: A0A0K2B2Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

278992:SAM23877 RS25365
gene id: 278992:SAM23877_RS25365
uniprot id: A0A0K2AZQ2
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

278992:SAM23877 RS17775
gene id: 278992:SAM23877_RS17775
uniprot id: A0A0K2AUV4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS35840
gene id: 278992:SAM23877_RS35840
uniprot id: Q1RR19
names: Subcellular Location Annotation
messages: Cytoplasm

278992:SAM23877 RS09485
gene id: 278992:SAM23877_RS09485
uniprot id: A0A0K2AQ91
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

278992:SAM23877 RS10090
gene id: 278992:SAM23877_RS10090
uniprot id: A0A0K2AQ12
names: Subcellular Location Annotation
messages: Cytoplasm

278992:SAM23877 RS14720
gene id: 278992:SAM23877_RS14720
uniprot id: A0A0K2AT72
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS28715
gene id: 278992:SAM23877_RS28715
uniprot id: A0A0K2B1S7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

278992:SAM23877 RS09000
gene id: 278992:SAM23877_RS09000
uniprot id: A0A0K2APP7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

278992:SAM23877 RS21180
gene id: 278992:SAM23877_RS21180
uniprot id: A0A0K2AX20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

278992:SAM23877 RS25315
gene id: 278992:SAM23877_RS25315
uniprot id: A0A0K2AZ13
names: Similarity
messages: Belongs to the acylphosphatase family.

278992:SAM23877 RS27210
gene id: 278992:SAM23877_RS27210
uniprot id: A0A0K2B0N0
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS06905
gene id: 278992:SAM23877_RS06905
uniprot id: A3KKZ8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

278992:SAM23877 RS03195
gene id: 278992:SAM23877_RS03195
uniprot id: A3KIV7
names: Similarity
messages: Belongs to the cytochrome P450 family.

278992:SAM23877 RS22430
gene id: 278992:SAM23877_RS22430
uniprot id: A0A0K2AXY7
names: Subcellular Location Annotation
messages: Cell membrane

278992:SAM23877 RS07110
gene id: 278992:SAM23877_RS07110
uniprot id: A0A0K2AP30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

278992:SAM23877 RS30110
gene id: 278992:SAM23877_RS30110
uniprot id: A0A0K2B284
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

278992:SAM23877 RS31100
gene id: 278992:SAM23877_RS31100
uniprot id: A0AE18
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

278992:SAM23877 RS31440
gene id: 278992:SAM23877_RS31440
uniprot id: A0ADV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

278992:SAM23877 RS12280
gene id: 278992:SAM23877_RS12280
uniprot id: A0A0K2ARN7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

278992:SAM23877 RS22195
gene id: 278992:SAM23877_RS22195
uniprot id: A0A0K2AY19
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

278992:SAM23877 RS18695
gene id: 278992:SAM23877_RS18695
uniprot id: A0A0K2AVH1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

278992:SAM23877 RS29570
gene id: 278992:SAM23877_RS29570
uniprot id: A0A0K2B1L7
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS25230
gene id: 278992:SAM23877_RS25230
uniprot id: A0A0K2AZA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

278992:SAM23877 RS21325
gene id: 278992:SAM23877_RS21325
uniprot id: A0A0K2AXK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

278992:SAM23877 RS30000
gene id: 278992:SAM23877_RS30000
uniprot id: A0A0K2B2P2
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

278992:SAM23877 RS28270
gene id: 278992:SAM23877_RS28270
uniprot id: A0A0K2B1L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

278992:SAM23877 RS08015
gene id: 278992:SAM23877_RS08015
uniprot id: A0A0K2AP44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

278992:SAM23877 RS20715
gene id: 278992:SAM23877_RS20715
uniprot id: A0A0K2AWQ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

278992:SAM23877 RS02310
gene id: 278992:SAM23877_RS02310
uniprot id: A3KID5
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

278992:SAM23877 RS09460
gene id: 278992:SAM23877_RS09460
uniprot id: A0A0K2AQ86
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

278992:SAM23877 RS20400
gene id: 278992:SAM23877_RS20400
uniprot id: A0A0K2AWI6
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS14465
gene id: 278992:SAM23877_RS14465
uniprot id: A0A0K2ATH6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

278992:SAM23877 RS11120
gene id: 278992:SAM23877_RS11120
uniprot id: A0A0K2ARF9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

278992:SAM23877 RS11560
gene id: 278992:SAM23877_RS11560
uniprot id: A0A0K2AQY7
names: Similarity
messages: Belongs to the CdaR family.

278992:SAM23877 RS23700
gene id: 278992:SAM23877_RS23700
uniprot id: A0A0K2AYF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

278992:SAM23877 RS16190
gene id: 278992:SAM23877_RS16190
uniprot id: A0A0K2AU95
names: Similarity
messages: Belongs to the peptidase M1 family.

278992:SAM23877 RS19920
gene id: 278992:SAM23877_RS19920
uniprot id: A0A0K2AW53
names: Similarity
messages: Belongs to the Nth/MutY family.

278992:SAM23877 RS13000
gene id: 278992:SAM23877_RS13000
uniprot id: A0A0K2AS35
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

278992:SAM23877 RS21470
gene id: 278992:SAM23877_RS21470
uniprot id: A0A0K2AWS9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

278992:SAM23877 RS34230
gene id: 278992:SAM23877_RS34230
uniprot id: A0AC97
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

278992:SAM23877 RS27460
gene id: 278992:SAM23877_RS27460
uniprot id: A0A0K2B0M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS19525
gene id: 278992:SAM23877_RS19525
uniprot id: A0A0K2AVX6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

278992:SAM23877 RS25705
gene id: 278992:SAM23877_RS25705
uniprot id: A0A0K2AZK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS23705
gene id: 278992:SAM23877_RS23705
uniprot id: A0A0K2AY54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

278992:SAM23877 RS18280
gene id: 278992:SAM23877_RS18280
uniprot id: A0A0K2AVP5
names: Similarity
messages: Belongs to the LOR family.

278992:SAM23877 RS25785
gene id: 278992:SAM23877_RS25785
uniprot id: A0A0K2AZB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

278992:SAM23877 RS18305
gene id: 278992:SAM23877_RS18305
uniprot id: A0A0K2AVQ0
names: Similarity
messages: Belongs to the pirin family.

278992:SAM23877 RS22405
gene id: 278992:SAM23877_RS22405
uniprot id: A0A0K2AXY3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS29420
gene id: 278992:SAM23877_RS29420
uniprot id: A0A0K2B1T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.
messages: gas vesicle membrane

278992:SAM23877 RS24105
gene id: 278992:SAM23877_RS24105
uniprot id: A0A0K2AZ76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

278992:SAM23877 RS12650
gene id: 278992:SAM23877_RS12650
uniprot id: A0A0K2ARW3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS34545
gene id: 278992:SAM23877_RS34545
uniprot id: A0AC37
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS33575
gene id: 278992:SAM23877_RS33575
uniprot id: A0ACM5
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS07810
gene id: 278992:SAM23877_RS07810
uniprot id: A0A0K2ANQ0
names: Similarity
messages: Belongs to the cytochrome P450 family.

278992:SAM23877 RS15295
gene id: 278992:SAM23877_RS15295
uniprot id: A0A0K2ATI6
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

278992:SAM23877 RS02175
gene id: 278992:SAM23877_RS02175
uniprot id: A3KIA8
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

278992:SAM23877 RS21010
gene id: 278992:SAM23877_RS21010
uniprot id: A0A0K2AWH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

278992:SAM23877 RS05960
gene id: 278992:SAM23877_RS05960
uniprot id: A3KKG2
names: Similarity
messages: Belongs to the pirin family.

278992:SAM23877 RS06635
gene id: 278992:SAM23877_RS06635
uniprot id: A0A0K2ANK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

278992:SAM23877 RS29965
gene id: 278992:SAM23877_RS29965
uniprot id: A0A0K2B1U5
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

278992:SAM23877 RS14455
gene id: 278992:SAM23877_RS14455
uniprot id: A0A0K2ASZ0
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

278992:SAM23877 RS18310
gene id: 278992:SAM23877_RS18310
uniprot id: A0A0K2AV90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

278992:SAM23877 RS15585
gene id: 278992:SAM23877_RS15585
uniprot id: A0A0K2ATM0
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

278992:SAM23877 RS17765
gene id: 278992:SAM23877_RS17765
uniprot id: A0A0K2AVE3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

278992:SAM23877 RS04685
gene id: 278992:SAM23877_RS04685
uniprot id: A3KJQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

278992:SAM23877 RS24365
gene id: 278992:SAM23877_RS24365
uniprot id: A0A0K2AYH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

278992:SAM23877 RS36820
gene id: 278992:SAM23877_RS36820
uniprot id: A0A0K2B0L6
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS08745
gene id: 278992:SAM23877_RS08745
uniprot id: A0A0K2APL3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

278992:SAM23877 RS10185
gene id: 278992:SAM23877_RS10185
uniprot id: A0A0K2AQN3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

278992:SAM23877 RS33620
gene id: 278992:SAM23877_RS33620
uniprot id: A0ACL6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

278992:SAM23877 RS04880
gene id: 278992:SAM23877_RS04880
uniprot id: A3KJU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS25875
gene id: 278992:SAM23877_RS25875
uniprot id: A0A0K2B011
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

278992:SAM23877 RS20865
gene id: 278992:SAM23877_RS20865
uniprot id: A0A0K2AWE2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

278992:SAM23877 RS21150
gene id: 278992:SAM23877_RS21150
uniprot id: A0A0K2AX14
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

278992:SAM23877 RS28035
gene id: 278992:SAM23877_RS28035
uniprot id: A0A0K2B0P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

278992:SAM23877 RS09040
gene id: 278992:SAM23877_RS09040
uniprot id: A0A0K2AQ57
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

278992:SAM23877 RS09455
gene id: 278992:SAM23877_RS09455
uniprot id: A0A0K2APQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

278992:SAM23877 RS13305
gene id: 278992:SAM23877_RS13305
uniprot id: A0A0K2AS92
names: Similarity
messages: Belongs to the universal stress protein A family.

278992:SAM23877 RS32095
gene id: 278992:SAM23877_RS32095
uniprot id: A0ADH0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

278992:SAM23877 RS14905
gene id: 278992:SAM23877_RS14905
uniprot id: A0A0K2ATR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

278992:SAM23877 RS13265
gene id: 278992:SAM23877_RS13265
uniprot id: A0A0K2ASG1
names: Similarity
messages: Belongs to the group II decarboxylase family.

278992:SAM23877 RS33530
gene id: 278992:SAM23877_RS33530
uniprot id: A0ACN3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

278992:SAM23877 RS20430
gene id: 278992:SAM23877_RS20430
uniprot id: A0A0K2AWG1
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

278992:SAM23877 RS19490
gene id: 278992:SAM23877_RS19490
uniprot id: A0A0K2AWG9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

278992:SAM23877 RS26655
gene id: 278992:SAM23877_RS26655
uniprot id: A0A0K2B053
names: Similarity
messages: Belongs to the cytochrome P450 family.

278992:SAM23877 RS07765
gene id: 278992:SAM23877_RS07765
uniprot id: A0A0K2ANP0
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS17970
gene id: 278992:SAM23877_RS17970
uniprot id: A0A0K2AUZ6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

278992:SAM23877 RS10025
gene id: 278992:SAM23877_RS10025
uniprot id: A0A0K2AQJ7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

278992:SAM23877 RS12925
gene id: 278992:SAM23877_RS12925
uniprot id: A0A0K2AS19
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

278992:SAM23877 RS22390
gene id: 278992:SAM23877_RS22390
uniprot id: A0A0K2AXS6
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS20625
gene id: 278992:SAM23877_RS20625
uniprot id: A0A0K2AWK2
names: Similarity
messages: Belongs to the GSP E family.

278992:SAM23877 RS11385
gene id: 278992:SAM23877_RS11385
uniprot id: A0A0K2AQT4
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS27645
gene id: 278992:SAM23877_RS27645
uniprot id: A0A0K2B176
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

278992:SAM23877 RS19670
gene id: 278992:SAM23877_RS19670
uniprot id: A0A0K2AWB6
names: Similarity
messages: Belongs to the UPF0145 family.

278992:SAM23877 RS29950
gene id: 278992:SAM23877_RS29950
uniprot id: A0A0K2B2N2
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS23685
gene id: 278992:SAM23877_RS23685
uniprot id: A0A0K2AYS0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

278992:SAM23877 RS09405
gene id: 278992:SAM23877_RS09405
uniprot id: A0A0K2APP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS18585
gene id: 278992:SAM23877_RS18585
uniprot id: A0A0K2AVB2
names: Subcellular Location Annotation
messages: Cytoplasm

278992:SAM23877 RS29960
gene id: 278992:SAM23877_RS29960
uniprot id: A0A0K2B255
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS26695
gene id: 278992:SAM23877_RS26695
uniprot id: A0A0K2B0P6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

278992:SAM23877 RS07930
gene id: 278992:SAM23877_RS07930
uniprot id: A0A0K2ANS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

278992:SAM23877 RS13610
gene id: 278992:SAM23877_RS13610
uniprot id: A0A0K2ASE9
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

278992:SAM23877 RS24560
gene id: 278992:SAM23877_RS24560
uniprot id: A0A0K2AYK9
names: Subcellular Location Annotation
messages: Cytoplasm

278992:SAM23877 RS12145
gene id: 278992:SAM23877_RS12145
uniprot id: A0A0K2ARK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

278992:SAM23877 RS31520
gene id: 278992:SAM23877_RS31520
uniprot id: A0ADT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

278992:SAM23877 RS13280
gene id: 278992:SAM23877_RS13280
uniprot id: A0A0K2AS87
names: Similarity
messages: Belongs to the IucA/IucC family.

278992:SAM23877 RS13345
gene id: 278992:SAM23877_RS13345
uniprot id: A0A0K2ASC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS17000
gene id: 278992:SAM23877_RS17000
uniprot id: A0A0K2AUH7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm
messages: Homodimer.

278992:SAM23877 RS06975
gene id: 278992:SAM23877_RS06975
uniprot id: A0A0K2ANA8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

278992:SAM23877 RS23400
gene id: 278992:SAM23877_RS23400
uniprot id: A0A0K2AYI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

278992:SAM23877 RS06790
gene id: 278992:SAM23877_RS06790
uniprot id: A3KKX4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

278992:SAM23877 RS10695
gene id: 278992:SAM23877_RS10695
uniprot id: A0A0K2AQR1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

278992:SAM23877 RS00425
gene id: 278992:SAM23877_RS00425
uniprot id: Q1RQZ4
names: Subcellular Location Annotation
messages: Cytoplasm

278992:SAM23877 RS30545
gene id: 278992:SAM23877_RS30545
uniprot id: A0AEC6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS18260
gene id: 278992:SAM23877_RS18260
uniprot id: A0A0K2AV80
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS02925
gene id: 278992:SAM23877_RS02925
uniprot id: A3KIQ3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS30455
gene id: 278992:SAM23877_RS30455
uniprot id: A0A0K2B2Y3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

278992:SAM23877 RS18845
gene id: 278992:SAM23877_RS18845
uniprot id: A0A0K2AVL9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS30245
gene id: 278992:SAM23877_RS30245
uniprot id: A0A0K2B2I0
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS24140
gene id: 278992:SAM23877_RS24140
uniprot id: A0A0K2AYN1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

278992:SAM23877 RS20425
gene id: 278992:SAM23877_RS20425
uniprot id: A0A0K2AWJ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

278992:SAM23877 RS23780
gene id: 278992:SAM23877_RS23780
uniprot id: A0A0K2AY69
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

278992:SAM23877 RS22340
gene id: 278992:SAM23877_RS22340
uniprot id: A0A0K2AY48
names: Similarity
messages: Belongs to the BMP lipoprotein family.

278992:SAM23877 RS28345
gene id: 278992:SAM23877_RS28345
uniprot id: A0A0K2B1Q2
names: Similarity
messages: Belongs to the malate synthase family.

278992:SAM23877 RS27820
gene id: 278992:SAM23877_RS27820
uniprot id: A0A0K2B1B3
names: Cofactor
messages: Binds 1 zinc ion per subunit.

278992:SAM23877 RS20260
gene id: 278992:SAM23877_RS20260
uniprot id: A0A0K2AWN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS34290
gene id: 278992:SAM23877_RS34290
uniprot id: A0AC85
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

278992:SAM23877 RS33710
gene id: 278992:SAM23877_RS33710
uniprot id: A0A0K2B513
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

278992:SAM23877 RS27045
gene id: 278992:SAM23877_RS27045
uniprot id: A0A0K2B029
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

278992:SAM23877 RS08090
gene id: 278992:SAM23877_RS08090
uniprot id: A0A0K2AP81
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS06880
gene id: 278992:SAM23877_RS06880
uniprot id: A3KKZ3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS28500
gene id: 278992:SAM23877_RS28500
uniprot id: A0A0K2B1H4
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS12445
gene id: 278992:SAM23877_RS12445
uniprot id: A0A0K2AS00
names: Cofactor
messages: Binds 1 zinc ion per subunit.

278992:SAM23877 RS03800
gene id: 278992:SAM23877_RS03800
uniprot id: A3KJ79
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS06875
gene id: 278992:SAM23877_RS06875
uniprot id: A3KKZ2
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS12240
gene id: 278992:SAM23877_RS12240
uniprot id: A0A0K2ARM6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

278992:SAM23877 RS06615
gene id: 278992:SAM23877_RS06615
uniprot id: A3KKU2
names: Similarity
messages: Belongs to the UPF0749 family.

278992:SAM23877 RS27440
gene id: 278992:SAM23877_RS27440
uniprot id: A0A0K2B0A5
names: Subcellular Location Annotation
messages: Cell membrane

278992:SAM23877 RS23120
gene id: 278992:SAM23877_RS23120
uniprot id: A0A0K2AYC7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

278992:SAM23877 RS32445
gene id: 278992:SAM23877_RS32445
uniprot id: A0ADA0
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS10075
gene id: 278992:SAM23877_RS10075
uniprot id: A0A0K2AQK7
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS25635
gene id: 278992:SAM23877_RS25635
uniprot id: A0A0K2AZ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS09380
gene id: 278992:SAM23877_RS09380
uniprot id: A0A0K2APN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

278992:SAM23877 RS21080
gene id: 278992:SAM23877_RS21080
uniprot id: A0A0K2AWU7
names: Similarity
messages: Belongs to the UPF0234 family.

278992:SAM23877 RS33340
gene id: 278992:SAM23877_RS33340
uniprot id: A0ACS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

278992:SAM23877 RS34825
gene id: 278992:SAM23877_RS34825
uniprot id: A0A0K2B564
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

278992:SAM23877 RS21225
gene id: 278992:SAM23877_RS21225
uniprot id: A0A0K2AX30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

278992:SAM23877 RS24815
gene id: 278992:SAM23877_RS24815
uniprot id: A0A0K2AZ80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS31815
gene id: 278992:SAM23877_RS31815
uniprot id: A0ADM6
names: Similarity
messages: Belongs to the peptidase S1 family.

278992:SAM23877 RS16055
gene id: 278992:SAM23877_RS16055
uniprot id: A0A0K2ATZ2
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS13340
gene id: 278992:SAM23877_RS13340
uniprot id: A0A0K2ASS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS25490
gene id: 278992:SAM23877_RS25490
uniprot id: A0A0K2AZS7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS35460
gene id: 278992:SAM23877_RS35460
uniprot id: Q1RQT9
names: Similarity
messages: Belongs to the glutamine synthetase family.

278992:SAM23877 RS18940
gene id: 278992:SAM23877_RS18940
uniprot id: A0A0K2AW52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

278992:SAM23877 RS21285
gene id: 278992:SAM23877_RS21285
uniprot id: A0A0K2AWZ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS20815
gene id: 278992:SAM23877_RS20815
uniprot id: A0A0K2AWC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

278992:SAM23877 RS07660
gene id: 278992:SAM23877_RS07660
uniprot id: A0A0K2ANZ1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

278992:SAM23877 RS13250
gene id: 278992:SAM23877_RS13250
uniprot id: A0A0K2ASA9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

278992:SAM23877 RS00745
gene id: 278992:SAM23877_RS00745
uniprot id: Q1RQS9
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

278992:SAM23877 RS25190
gene id: 278992:SAM23877_RS25190
uniprot id: A0A0K2AYY3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

278992:SAM23877 RS14385
gene id: 278992:SAM23877_RS14385
uniprot id: A0A0K2AT49
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

278992:SAM23877 RS04825
gene id: 278992:SAM23877_RS04825
uniprot id: A3KJT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

278992:SAM23877 RS17225
gene id: 278992:SAM23877_RS17225
uniprot id: A0A0K2AUL3
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

278992:SAM23877 RS14100
gene id: 278992:SAM23877_RS14100
uniprot id: A0A0K2ATA4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

278992:SAM23877 RS24195
gene id: 278992:SAM23877_RS24195
uniprot id: A0A0K2AYP0
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

278992:SAM23877 RS14985
gene id: 278992:SAM23877_RS14985
uniprot id: A0A0K2ASX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

278992:SAM23877 RS23365
gene id: 278992:SAM23877_RS23365
uniprot id: A0A0K2AYC4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

278992:SAM23877 RS08675
gene id: 278992:SAM23877_RS08675
uniprot id: A0A0K2APJ6
names: Similarity
messages: Belongs to the UPF0098 family.

278992:SAM23877 RS26035
gene id: 278992:SAM23877_RS26035
uniprot id: A0A0K2B064
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

278992:SAM23877 RS19355
gene id: 278992:SAM23877_RS19355
uniprot id: A0A0K2AVX2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

278992:SAM23877 RS15735
gene id: 278992:SAM23877_RS15735
uniprot id: A0A0K2ATZ6
names: Similarity
messages: Belongs to the citrate synthase family.

278992:SAM23877 RS03410
gene id: 278992:SAM23877_RS03410
uniprot id: A3KJ00
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS32990
gene id: 278992:SAM23877_RS32990
uniprot id: A0ACY9
names: Similarity
messages: Belongs to the cytochrome P450 family.

278992:SAM23877 RS20495
gene id: 278992:SAM23877_RS20495
uniprot id: A0A0K2AWK4
names: Subcellular Location Annotation
messages: Cytoplasm

278992:SAM23877 RS03345
gene id: 278992:SAM23877_RS03345
uniprot id: A3KIY7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

278992:SAM23877 RS30580
gene id: 278992:SAM23877_RS30580
uniprot id: A0AEC0
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS12430
gene id: 278992:SAM23877_RS12430
uniprot id: A0A0K2AS97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

278992:SAM23877 RS23040
gene id: 278992:SAM23877_RS23040
uniprot id: A0A0K2AXN8
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS31750
gene id: 278992:SAM23877_RS31750
uniprot id: A0ADN8
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS25850
gene id: 278992:SAM23877_RS25850
uniprot id: A0A0K2B004
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

278992:SAM23877 RS05225
gene id: 278992:SAM23877_RS05225
uniprot id: A0A0K2AMZ1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

278992:SAM23877 RS05165
gene id: 278992:SAM23877_RS05165
uniprot id: A3KK04
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

278992:SAM23877 RS09295
gene id: 278992:SAM23877_RS09295
uniprot id: A0A0K2APX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS02320
gene id: 278992:SAM23877_RS02320
uniprot id: A3KID7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS09440
gene id: 278992:SAM23877_RS09440
uniprot id: A0A0K2AQG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

278992:SAM23877 RS20105
gene id: 278992:SAM23877_RS20105
uniprot id: A0A0K2AVW9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

278992:SAM23877 RS17670
gene id: 278992:SAM23877_RS17670
uniprot id: A0A0K2AV42
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

278992:SAM23877 RS03460
gene id: 278992:SAM23877_RS03460
uniprot id: A3KJ10
names: Similarity
messages: Belongs to the cytochrome P450 family.

278992:SAM23877 RS08395
gene id: 278992:SAM23877_RS08395
uniprot id: A0A0K2APS6
names: Similarity
messages: Belongs to the peptidase S1 family.

278992:SAM23877 RS27540
gene id: 278992:SAM23877_RS27540
uniprot id: A0A0K2B0C8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted

278992:SAM23877 RS10930
gene id: 278992:SAM23877_RS10930
uniprot id: A0A0K2AQU7
names: Similarity
messages: Belongs to the YoeB family.

278992:SAM23877 RS32980
gene id: 278992:SAM23877_RS32980
uniprot id: A0ACZ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

278992:SAM23877 RS08110
gene id: 278992:SAM23877_RS08110
uniprot id: A0A0K2AP62
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS04005
gene id: 278992:SAM23877_RS04005
uniprot id: A0A0K2AM65
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS30540
gene id: 278992:SAM23877_RS30540
uniprot id: A0A0K2B273
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

278992:SAM23877 RS03730
gene id: 278992:SAM23877_RS03730
uniprot id: A0A0K2AM08
names: Similarity
messages: Belongs to the cytochrome P450 family.

278992:SAM23877 RS19500
gene id: 278992:SAM23877_RS19500
uniprot id: A0A0K2AVX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

278992:SAM23877 RS22385
gene id: 278992:SAM23877_RS22385
uniprot id: A0A0K2AY57
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

278992:SAM23877 RS24335
gene id: 278992:SAM23877_RS24335
uniprot id: A0A0K2AYY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS31330
gene id: 278992:SAM23877_RS31330
uniprot id: A0ADX3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS21550
gene id: 278992:SAM23877_RS21550
uniprot id: A0A0K2AXP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

278992:SAM23877 RS25720
gene id: 278992:SAM23877_RS25720
uniprot id: A0A0K2B032
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

278992:SAM23877 RS15050
gene id: 278992:SAM23877_RS15050
uniprot id: A0A0K2ATB2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

278992:SAM23877 RS01435
gene id: 278992:SAM23877_RS01435
uniprot id: A3KHW2
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS26300
gene id: 278992:SAM23877_RS26300
uniprot id: A0A0K2B044
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

278992:SAM23877 RS22495
gene id: 278992:SAM23877_RS22495
uniprot id: A0A0K2AXB9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

278992:SAM23877 RS26420
gene id: 278992:SAM23877_RS26420
uniprot id: A0A0K2B009
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

278992:SAM23877 RS10490
gene id: 278992:SAM23877_RS10490
uniprot id: A0A0K2AQM3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS10035
gene id: 278992:SAM23877_RS10035
uniprot id: A0A0K2AQA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

278992:SAM23877 RS20485
gene id: 278992:SAM23877_RS20485
uniprot id: A0A0K2AWT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

278992:SAM23877 RS09865
gene id: 278992:SAM23877_RS09865
uniprot id: A0A0K2AQ76
names: Similarity
messages: Belongs to the peptidase M1 family.

278992:SAM23877 RS33045
gene id: 278992:SAM23877_RS33045
uniprot id: A0A0K2B3R8
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS18090
gene id: 278992:SAM23877_RS18090
uniprot id: A0A0K2AV19
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

278992:SAM23877 RS36400
gene id: 278992:SAM23877_RS36400
uniprot id: A0A0K2B6R2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS35480
gene id: 278992:SAM23877_RS35480
uniprot id: Q1RQU3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS23875
gene id: 278992:SAM23877_RS23875
uniprot id: A0A0K2AYV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

278992:SAM23877 RS20765
gene id: 278992:SAM23877_RS20765
uniprot id: A0A0K2AWB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

278992:SAM23877 RS06870
gene id: 278992:SAM23877_RS06870
uniprot id: A3KKZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

278992:SAM23877 RS21435
gene id: 278992:SAM23877_RS21435
uniprot id: A0A0K2AX25
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

278992:SAM23877 RS19590
gene id: 278992:SAM23877_RS19590
uniprot id: A0A0K2AVL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

278992:SAM23877 RS30185
gene id: 278992:SAM23877_RS30185
uniprot id: A0A0K2B1Z4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

278992:SAM23877 RS09850
gene id: 278992:SAM23877_RS09850
uniprot id: A0A0K2APW3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

278992:SAM23877 RS08820
gene id: 278992:SAM23877_RS08820
uniprot id: A0A0K2APU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

278992:SAM23877 RS11960
gene id: 278992:SAM23877_RS11960
uniprot id: A0A0K2ARH0
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

278992:SAM23877 RS10890
gene id: 278992:SAM23877_RS10890
uniprot id: A0A0K2AQV4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

278992:SAM23877 RS11850
gene id: 278992:SAM23877_RS11850
uniprot id: A0A0K2ARF2
names: Similarity
messages: Belongs to the FGGY kinase family.

278992:SAM23877 RS29740
gene id: 278992:SAM23877_RS29740
uniprot id: A0A0K2B1P7
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

278992:SAM23877 RS06010
gene id: 278992:SAM23877_RS06010
uniprot id: A3KKH2
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

278992:SAM23877 RS30065
gene id: 278992:SAM23877_RS30065
uniprot id: A0A0K2B1W8
names: Similarity
messages: Belongs to the proline racemase family.

278992:SAM23877 RS35365
gene id: 278992:SAM23877_RS35365
uniprot id: Q1RQS0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

278992:SAM23877 RS31455
gene id: 278992:SAM23877_RS31455
uniprot id: A0ADU7
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

278992:SAM23877 RS28285
gene id: 278992:SAM23877_RS28285
uniprot id: A0A0K2B0V0
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS11005
gene id: 278992:SAM23877_RS11005
uniprot id: A0A0K2AQW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS02230
gene id: 278992:SAM23877_RS02230
uniprot id: A3KIB9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

278992:SAM23877 RS29495
gene id: 278992:SAM23877_RS29495
uniprot id: A0A0K2B1V4
names: Similarity
messages: Belongs to the peptidase C56 family.

278992:SAM23877 RS13830
gene id: 278992:SAM23877_RS13830
uniprot id: A0A0K2ASS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS25415
gene id: 278992:SAM23877_RS25415
uniprot id: A0A0K2AZR3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

278992:SAM23877 RS07895
gene id: 278992:SAM23877_RS07895
uniprot id: A0A0K2APH8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

278992:SAM23877 RS24265
gene id: 278992:SAM23877_RS24265
uniprot id: A0A0K2AYQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

278992:SAM23877 RS10160
gene id: 278992:SAM23877_RS10160
uniprot id: A0A0K2AQM8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

278992:SAM23877 RS19745
gene id: 278992:SAM23877_RS19745
uniprot id: A0A0K2AWD1
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS35490
gene id: 278992:SAM23877_RS35490
uniprot id: Q1RQU5
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS23220
gene id: 278992:SAM23877_RS23220
uniprot id: A0A0K2AY98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS23160
gene id: 278992:SAM23877_RS23160
uniprot id: A0A0K2AY13
names: Similarity
messages: Belongs to the Nudix hydrolase family.

278992:SAM23877 RS02030
gene id: 278992:SAM23877_RS02030
uniprot id: A3KI80
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

278992:SAM23877 RS14510
gene id: 278992:SAM23877_RS14510
uniprot id: A0A0K2ATI4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS25070
gene id: 278992:SAM23877_RS25070
uniprot id: A0A0K2AZD7
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS03540
gene id: 278992:SAM23877_RS03540
uniprot id: A3KJ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

278992:SAM23877 RS32995
gene id: 278992:SAM23877_RS32995
uniprot id: A0ACY8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

278992:SAM23877 RS28520
gene id: 278992:SAM23877_RS28520
uniprot id: A0A0K2B1T8
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS24545
gene id: 278992:SAM23877_RS24545
uniprot id: A0A0K2AZF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS32670
gene id: 278992:SAM23877_RS32670
uniprot id: A0AD53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS15110
gene id: 278992:SAM23877_RS15110
uniprot id: A0A0K2ATL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

278992:SAM23877 RS25485
gene id: 278992:SAM23877_RS25485
uniprot id: A0A0K2AZ53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

278992:SAM23877 RS14240
gene id: 278992:SAM23877_RS14240
uniprot id: A0A0K2ASX3
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

278992:SAM23877 RS04135
gene id: 278992:SAM23877_RS04135
uniprot id: A3KJE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

278992:SAM23877 RS03270
gene id: 278992:SAM23877_RS03270
uniprot id: A3KIX1
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

278992:SAM23877 RS03545
gene id: 278992:SAM23877_RS03545
uniprot id: A0A0K2AL88
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

278992:SAM23877 RS10670
gene id: 278992:SAM23877_RS10670
uniprot id: A0A0K2AQQ6
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

278992:SAM23877 RS05710
gene id: 278992:SAM23877_RS05710
uniprot id: A3KKB1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS10920
gene id: 278992:SAM23877_RS10920
uniprot id: A0A0K2AR19
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

278992:SAM23877 RS31235
gene id: 278992:SAM23877_RS31235
uniprot id: A0ADZ3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS30325
gene id: 278992:SAM23877_RS30325
uniprot id: A0A0K2B2C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

278992:SAM23877 RS26430
gene id: 278992:SAM23877_RS26430
uniprot id: A0A0K2B0J6
names: Subcellular Location Annotation
messages: Cell membrane

278992:SAM23877 RS01450
gene id: 278992:SAM23877_RS01450
uniprot id: A3KHW6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

278992:SAM23877 RS11780
gene id: 278992:SAM23877_RS11780
uniprot id: A0A0K2ARX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

278992:SAM23877 RS13560
gene id: 278992:SAM23877_RS13560
uniprot id: A0A0K2ASM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS10730
gene id: 278992:SAM23877_RS10730
uniprot id: A0A0K2AQY4
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS17790
gene id: 278992:SAM23877_RS17790
uniprot id: A0A0K2AVE8
names: Similarity
messages: Belongs to the FemABX family.

278992:SAM23877 RS05600
gene id: 278992:SAM23877_RS05600
uniprot id: A3KK89
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

278992:SAM23877 RS23320
gene id: 278992:SAM23877_RS23320
uniprot id: A0A0K2AYB5
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

278992:SAM23877 RS10760
gene id: 278992:SAM23877_RS10760
uniprot id: A0A0K2AQR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

278992:SAM23877 RS07065
gene id: 278992:SAM23877_RS07065
uniprot id: A0A0K2ANL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

278992:SAM23877 RS03060
gene id: 278992:SAM23877_RS03060
uniprot id: A3KIT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

278992:SAM23877 RS07340
gene id: 278992:SAM23877_RS07340
uniprot id: A0A0K2ANR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS27545
gene id: 278992:SAM23877_RS27545
uniprot id: A0A0K2B114
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

278992:SAM23877 RS32705
gene id: 278992:SAM23877_RS32705
uniprot id: A0AD46
names: Function
names: Similarity
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.

278992:SAM23877 RS05615
gene id: 278992:SAM23877_RS05615
uniprot id: A3KK92
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

278992:SAM23877 RS15885
gene id: 278992:SAM23877_RS15885
uniprot id: A0A0K2ATV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

278992:SAM23877 RS15305
gene id: 278992:SAM23877_RS15305
uniprot id: A0A0K2AT43
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS03370
gene id: 278992:SAM23877_RS03370
uniprot id: A3KIZ2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

278992:SAM23877 RS17010
gene id: 278992:SAM23877_RS17010
uniprot id: A0A0K2AUF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

278992:SAM23877 RS26455
gene id: 278992:SAM23877_RS26455
uniprot id: A0A0K2B076
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

278992:SAM23877 RS02535
gene id: 278992:SAM23877_RS02535
uniprot id: A3KIH7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS02360
gene id: 278992:SAM23877_RS02360
uniprot id: A0A0K2AKS0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

278992:SAM23877 RS13495
gene id: 278992:SAM23877_RS13495
uniprot id: A0A0K2ASF7
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

278992:SAM23877 RS28725
gene id: 278992:SAM23877_RS28725
uniprot id: A0A0K2B1L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS34630
gene id: 278992:SAM23877_RS34630
uniprot id: A0AC20
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS28585
gene id: 278992:SAM23877_RS28585
uniprot id: A0A0K2B1C5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

278992:SAM23877 RS02555
gene id: 278992:SAM23877_RS02555
uniprot id: A3KII1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M7 family.
messages: Secreted

278992:SAM23877 RS32050
gene id: 278992:SAM23877_RS32050
uniprot id: A0ADH9
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

278992:SAM23877 RS40670
gene id: 278992:SAM23877_RS40670
uniprot id: A0A0K2AZF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

278992:SAM23877 RS14115
gene id: 278992:SAM23877_RS14115
uniprot id: A0A0K2ASF8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

278992:SAM23877 RS10700
gene id: 278992:SAM23877_RS10700
uniprot id: A0A0K2AQD3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

278992:SAM23877 RS10995
gene id: 278992:SAM23877_RS10995
uniprot id: A0A0K2AR35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS27505
gene id: 278992:SAM23877_RS27505
uniprot id: A0A0K2B0U1
names: Similarity
messages: Belongs to the terpene synthase family.

278992:SAM23877 RS18975
gene id: 278992:SAM23877_RS18975
uniprot id: A0A0K2AVK8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

278992:SAM23877 RS31210
gene id: 278992:SAM23877_RS31210
uniprot id: A0ADZ8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

278992:SAM23877 RS15865
gene id: 278992:SAM23877_RS15865
uniprot id: A0A0K2ATS5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

278992:SAM23877 RS12200
gene id: 278992:SAM23877_RS12200
uniprot id: A0A0K2AR92
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

278992:SAM23877 RS13135
gene id: 278992:SAM23877_RS13135
uniprot id: A0A0K2AS61
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

278992:SAM23877 RS19635
gene id: 278992:SAM23877_RS19635
uniprot id: A0A0K2AVZ5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

278992:SAM23877 RS34405
gene id: 278992:SAM23877_RS34405
uniprot id: A0AC63
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

278992:SAM23877 RS09855
gene id: 278992:SAM23877_RS09855
uniprot id: A0A0K2AQG1
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

278992:SAM23877 RS09215
gene id: 278992:SAM23877_RS09215
uniprot id: A0A0K2AQB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS06380
gene id: 278992:SAM23877_RS06380
uniprot id: A3KKP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

278992:SAM23877 RS18010
gene id: 278992:SAM23877_RS18010
uniprot id: A0A0K2AV29
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS28330
gene id: 278992:SAM23877_RS28330
uniprot id: A0A0K2B178
names: Similarity
messages: Belongs to the IucA/IucC family.

278992:SAM23877 RS23000
gene id: 278992:SAM23877_RS23000
uniprot id: A0A0K2AYI1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

278992:SAM23877 RS31295
gene id: 278992:SAM23877_RS31295
uniprot id: A0ADY0
names: Similarity
messages: Belongs to the FPG family.

278992:SAM23877 RS09490
gene id: 278992:SAM23877_RS09490
uniprot id: A0A0K2AQH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

278992:SAM23877 RS08215
gene id: 278992:SAM23877_RS08215
uniprot id: A0A0K2APA6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

278992:SAM23877 RS05180
gene id: 278992:SAM23877_RS05180
uniprot id: A3KK07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS32015
gene id: 278992:SAM23877_RS32015
uniprot id: A0ADI6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

278992:SAM23877 RS01700
gene id: 278992:SAM23877_RS01700
uniprot id: A3KI18
names: Function
names: Similarity
messages: Belongs to the geranyl diphosphate 2-C-methyltransferase family.
messages: Catalyzes the SAM-dependent methylation of geranyl diphosphate (GPP) to yield (E)-2-methylgeranyl diphosphate (2-MeGPP).

278992:SAM23877 RS07525
gene id: 278992:SAM23877_RS07525
uniprot id: A0A0K2AP32
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS31875
gene id: 278992:SAM23877_RS31875
uniprot id: A0ADL4
names: Similarity
messages: Belongs to the peptidase S33 family.

278992:SAM23877 RS04900
gene id: 278992:SAM23877_RS04900
uniprot id: A3KJV0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

278992:SAM23877 RS25710
gene id: 278992:SAM23877_RS25710
uniprot id: A0A0K2AZA2
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

278992:SAM23877 RS05865
gene id: 278992:SAM23877_RS05865
uniprot id: A3KKE2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

278992:SAM23877 RS22170
gene id: 278992:SAM23877_RS22170
uniprot id: A0A0K2AY15
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

278992:SAM23877 RS25880
gene id: 278992:SAM23877_RS25880
uniprot id: A0A0K2AZU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

278992:SAM23877 RS33090
gene id: 278992:SAM23877_RS33090
uniprot id: A0ACW9
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

278992:SAM23877 RS10895
gene id: 278992:SAM23877_RS10895
uniprot id: A0A0K2AQH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS03200
gene id: 278992:SAM23877_RS03200
uniprot id: A3KIV8
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

278992:SAM23877 RS31090
gene id: 278992:SAM23877_RS31090
uniprot id: A0AE20
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

278992:SAM23877 RS21760
gene id: 278992:SAM23877_RS21760
uniprot id: A0A0K2AXT7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

278992:SAM23877 RS27405
gene id: 278992:SAM23877_RS27405
uniprot id: A0A0K2B0S0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

278992:SAM23877 RS34895
gene id: 278992:SAM23877_RS34895
uniprot id: A0ABX3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

278992:SAM23877 RS02995
gene id: 278992:SAM23877_RS02995
uniprot id: A3KIR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

278992:SAM23877 RS23985
gene id: 278992:SAM23877_RS23985
uniprot id: A0A0K2AYR9
names: Subcellular Location Annotation
messages: Cell membrane

278992:SAM23877 RS08955
gene id: 278992:SAM23877_RS08955
uniprot id: A0A0K2APR1
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

278992:SAM23877 RS27320
gene id: 278992:SAM23877_RS27320
uniprot id: A0A0K2B0X2
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS12740
gene id: 278992:SAM23877_RS12740
uniprot id: A0A0K2ASF5
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

278992:SAM23877 RS03995
gene id: 278992:SAM23877_RS03995
uniprot id: A3KJB7
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS25245
gene id: 278992:SAM23877_RS25245
uniprot id: A0A0K2AZT9
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

278992:SAM23877 RS08500
gene id: 278992:SAM23877_RS08500
uniprot id: A0A0K2APG6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

278992:SAM23877 RS02240
gene id: 278992:SAM23877_RS02240
uniprot id: A0A0K2AL53
names: Subcellular Location Annotation
messages: Cell membrane

278992:SAM23877 RS04715
gene id: 278992:SAM23877_RS04715
uniprot id: A3KJR1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

278992:SAM23877 RS13930
gene id: 278992:SAM23877_RS13930
uniprot id: A0A0K2AT50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

278992:SAM23877 RS17935
gene id: 278992:SAM23877_RS17935
uniprot id: A0A0K2AV16
names: Similarity
messages: Belongs to the UPF0232 family.

278992:SAM23877 RS31255
gene id: 278992:SAM23877_RS31255
uniprot id: A0A0K2B3A2
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

278992:SAM23877 RS30250
gene id: 278992:SAM23877_RS30250
uniprot id: A0A0K2B2B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

278992:SAM23877 RS14375
gene id: 278992:SAM23877_RS14375
uniprot id: A0A0K2ASX7
names: Subcellular Location Annotation
messages: Cell membrane

278992:SAM23877 RS19845
gene id: 278992:SAM23877_RS19845
uniprot id: A0A0K2AWF0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

278992:SAM23877 RS24005
gene id: 278992:SAM23877_RS24005
uniprot id: A0A0K2AZ57
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

278992:SAM23877 RS33005
gene id: 278992:SAM23877_RS33005
uniprot id: A0ACY6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

278992:SAM23877 RS24000
gene id: 278992:SAM23877_RS24000
uniprot id: A0A0K2AYX6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

278992:SAM23877 RS14275
gene id: 278992:SAM23877_RS14275
uniprot id: A0A0K2AT27
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

278992:SAM23877 RS26410
gene id: 278992:SAM23877_RS26410
uniprot id: A0A0K2B0J2
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS08995
gene id: 278992:SAM23877_RS08995
uniprot id: A0A0K2AQ43
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

278992:SAM23877 RS04225
gene id: 278992:SAM23877_RS04225
uniprot id: A3KJG3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS08455
gene id: 278992:SAM23877_RS08455
uniprot id: A0A0K2AP21
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

278992:SAM23877 RS32725
gene id: 278992:SAM23877_RS32725
uniprot id: A0AD42
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

278992:SAM23877 RS29890
gene id: 278992:SAM23877_RS29890
uniprot id: A0A0K2B239
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS11485
gene id: 278992:SAM23877_RS11485
uniprot id: A0A0K2AR69
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

278992:SAM23877 RS17780
gene id: 278992:SAM23877_RS17780
uniprot id: A0A0K2AUI0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

278992:SAM23877 RS20760
gene id: 278992:SAM23877_RS20760
uniprot id: A0A0K2AWM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

278992:SAM23877 RS21405
gene id: 278992:SAM23877_RS21405
uniprot id: A0A0K2AX61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

278992:SAM23877 RS10515
gene id: 278992:SAM23877_RS10515
uniprot id: A0A0K2AQM7
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS13200
gene id: 278992:SAM23877_RS13200
uniprot id: A0A0K2ASA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

278992:SAM23877 RS09240
gene id: 278992:SAM23877_RS09240
uniprot id: A0A0K2AQC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

278992:SAM23877 RS05275
gene id: 278992:SAM23877_RS05275
uniprot id: A3KK25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

278992:SAM23877 RS26070
gene id: 278992:SAM23877_RS26070
uniprot id: A0A0K2B003
names: Subcellular Location Annotation
messages: Cell membrane

278992:SAM23877 RS03240
gene id: 278992:SAM23877_RS03240
uniprot id: A3KIW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

278992:SAM23877 RS14300
gene id: 278992:SAM23877_RS14300
uniprot id: A0A0K2ATE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS28365
gene id: 278992:SAM23877_RS28365
uniprot id: A0A0K2B1L1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
messages: Homotetramer.

278992:SAM23877 RS22355
gene id: 278992:SAM23877_RS22355
uniprot id: A0A0K2AX93
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS24035
gene id: 278992:SAM23877_RS24035
uniprot id: A0A0K2AYS9
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

278992:SAM23877 RS18175
gene id: 278992:SAM23877_RS18175
uniprot id: A0A0K2AVM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

278992:SAM23877 RS00240
gene id: 278992:SAM23877_RS00240
uniprot id: Q1RR36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

278992:SAM23877 RS07215
gene id: 278992:SAM23877_RS07215
uniprot id: A0A0K2ANN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

278992:SAM23877 RS28260
gene id: 278992:SAM23877_RS28260
uniprot id: A0A0K2B0U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

278992:SAM23877 RS10195
gene id: 278992:SAM23877_RS10195
uniprot id: A0A0K2AQE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell membrane
messages: Essential cell division protein.

278992:SAM23877 RS08530
gene id: 278992:SAM23877_RS08530
uniprot id: A0A0K2AP38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

278992:SAM23877 RS26105
gene id: 278992:SAM23877_RS26105
uniprot id: A0A0K2AZK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

278992:SAM23877 RS09165
gene id: 278992:SAM23877_RS09165
uniprot id: A0A0K2AQA7
names: Similarity
messages: Belongs to the IlvD/Edd family.

278992:SAM23877 RS17560
gene id: 278992:SAM23877_RS17560
uniprot id: A0A0K2AUQ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

278992:SAM23877 RS07180
gene id: 278992:SAM23877_RS07180
uniprot id: A0A0K2AP45
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

278992:SAM23877 RS03010
gene id: 278992:SAM23877_RS03010
uniprot id: A3KIS0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

278992:SAM23877 RS16770
gene id: 278992:SAM23877_RS16770
uniprot id: A0A0K2AUW1
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

278992:SAM23877 RS09970
gene id: 278992:SAM23877_RS09970
uniprot id: A0A0K2APY7
names: Similarity
messages: Belongs to the TrpC family.

278992:SAM23877 RS14370
gene id: 278992:SAM23877_RS14370
uniprot id: A0A0K2AT02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpqB lipoprotein family.
messages: Cell membrane

278992:SAM23877 RS10040
gene id: 278992:SAM23877_RS10040
uniprot id: A0A0K2AQC9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

278992:SAM23877 RS14235
gene id: 278992:SAM23877_RS14235
uniprot id: A0A0K2ATD2
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

278992:SAM23877 RS18915
gene id: 278992:SAM23877_RS18915
uniprot id: A0A0K2AW47
names: Similarity
messages: Belongs to the cytochrome P450 family.

278992:SAM23877 RS28795
gene id: 278992:SAM23877_RS28795
uniprot id: A0A0K2B1Z5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

278992:SAM23877 RS20445
gene id: 278992:SAM23877_RS20445
uniprot id: A0A0K2AX01
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS07475
gene id: 278992:SAM23877_RS07475
uniprot id: A0A0K2AP22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

278992:SAM23877 RS31395
gene id: 278992:SAM23877_RS31395
uniprot id: A0ADV9
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

278992:SAM23877 RS00695
gene id: 278992:SAM23877_RS00695
uniprot id: Q1RQT9
names: Similarity
messages: Belongs to the glutamine synthetase family.

278992:SAM23877 RS24385
gene id: 278992:SAM23877_RS24385
uniprot id: A0A0K2AYT3
names: Subcellular Location Annotation
messages: Membrane

278992:SAM23877 RS33990
gene id: 278992:SAM23877_RS33990
uniprot id: A0ACE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

278992:SAM23877 RS11575
gene id: 278992:SAM23877_RS11575
uniprot id: A0A0K2ARA2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

278992:SAM23877 RS12205
gene id: 278992:SAM23877_RS12205
uniprot id: A0A0K2ARU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

278992:SAM23877 RS21445
gene id: 278992:SAM23877_RS21445
uniprot id: A0A0K2AXE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

278992:SAM23877 RS27050
gene id: 278992:SAM23877_RS27050
uniprot id: A0A0K2B0R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

278992:SAM23877 RS24660
gene id: 278992:SAM23877_RS24660
uniprot id: A0A0K2AYM8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

278992:SAM23877 RS21210
gene id: 278992:SAM23877_RS21210
uniprot id: A0A0K2AWY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

278992:SAM23877 RS14000
gene id: 278992:SAM23877_RS14000
uniprot id: A0A0K2ASX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane