273068:TTE RS07805
gene id: 273068:TTE_RS07805
uniprot id: Q8R9H7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

273068:TTE RS11745
gene id: 273068:TTE_RS11745
uniprot id: Q8R7F6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

273068:TTE RS01460
gene id: 273068:TTE_RS01460
uniprot id: Q8RCV4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

273068:TTE RS02815
gene id: 273068:TTE_RS02815
uniprot id: Q8RC55
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

273068:TTE RS00870
gene id: 273068:TTE_RS00870
uniprot id: Q8RD70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

273068:TTE RS05805
gene id: 273068:TTE_RS05805
uniprot id: Q8RAJ5
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

273068:TTE RS04765
gene id: 273068:TTE_RS04765
uniprot id: Q8R5T2
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

273068:TTE RS02180
gene id: 273068:TTE_RS02180
uniprot id: Q8RCH2
names: Similarity
messages: Belongs to the BMP lipoprotein family.

273068:TTE RS08660
gene id: 273068:TTE_RS08660
uniprot id: Q8R926
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

273068:TTE RS01455
gene id: 273068:TTE_RS01455
uniprot id: Q8RCV5
names: Similarity
messages: Belongs to the OsmC/Ohr family.

273068:TTE RS08740
gene id: 273068:TTE_RS08740
uniprot id: Q8R910
names: Function
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

273068:TTE RS01220
gene id: 273068:TTE_RS01220
uniprot id: Q8RD01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273068:TTE RS02580
gene id: 273068:TTE_RS02580
uniprot id: Q8RC95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

273068:TTE RS07035
gene id: 273068:TTE_RS07035
uniprot id: Q8R9W1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

273068:TTE RS11205
gene id: 273068:TTE_RS11205
uniprot id: Q8R7Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS13160
gene id: 273068:TTE_RS13160
uniprot id: Q8R6M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

273068:TTE RS11280
gene id: 273068:TTE_RS11280
uniprot id: Q8R6I5
names: Function
messages: Involved in the transposition of the insertion sequence.

273068:TTE RS00325
gene id: 273068:TTE_RS00325
uniprot id: Q8RDG8
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS05410
gene id: 273068:TTE_RS05410
uniprot id: Q8RAR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

273068:TTE RS11190
gene id: 273068:TTE_RS11190
uniprot id: Q8R7Q5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

273068:TTE RS02750
gene id: 273068:TTE_RS02750
uniprot id: Q8R5T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

273068:TTE RS08440
gene id: 273068:TTE_RS08440
uniprot id: Q8R969
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

273068:TTE RS02800
gene id: 273068:TTE_RS02800
uniprot id: Q8RC58
names: Similarity
messages: Belongs to the SAICAR synthetase family.

273068:TTE RS01100
gene id: 273068:TTE_RS01100
uniprot id: Q8RD24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS02755
gene id: 273068:TTE_RS02755
uniprot id: Q8R5T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

273068:TTE RS06815
gene id: 273068:TTE_RS06815
uniprot id: Q8RA03
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

273068:TTE RS02145
gene id: 273068:TTE_RS02145
uniprot id: Q8RCI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

273068:TTE RS00965
gene id: 273068:TTE_RS00965
uniprot id: Q8RD51
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS02205
gene id: 273068:TTE_RS02205
uniprot id: Q8RCG7
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

273068:TTE RS00120
gene id: 273068:TTE_RS00120
uniprot id: Q8RDJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

273068:TTE RS10815
gene id: 273068:TTE_RS10815
uniprot id: Q8R7Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

273068:TTE RS00025
gene id: 273068:TTE_RS00025
uniprot id: Q8RDL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

273068:TTE RS09615
gene id: 273068:TTE_RS09615
uniprot id: Q8R5R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

273068:TTE RS07575
gene id: 273068:TTE_RS07575
uniprot id: Q8R9L9
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS06195
gene id: 273068:TTE_RS06195
uniprot id: Q8RAC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

273068:TTE RS11940
gene id: 273068:TTE_RS11940
uniprot id: Q8R7C1
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

273068:TTE RS11060
gene id: 273068:TTE_RS11060
uniprot id: Q8R7T2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

273068:TTE RS10970
gene id: 273068:TTE_RS10970
uniprot id: Q8R7U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

273068:TTE RS06700
gene id: 273068:TTE_RS06700
uniprot id: Q8RA28
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

273068:TTE RS09230
gene id: 273068:TTE_RS09230
uniprot id: Q8R8R8
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

273068:TTE RS01000
gene id: 273068:TTE_RS01000
uniprot id: Q8RD43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
messages: Cell membrane
messages: Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system.
messages: The complex is composed of an ATP-binding protein (RbsA), two transmembrane proteins (RbsC) and a solute-binding protein (RbsB).

273068:TTE RS04335
gene id: 273068:TTE_RS04335
uniprot id: Q8RBB9
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

273068:TTE RS01925
gene id: 273068:TTE_RS01925
uniprot id: Q8RCV7
names: Similarity
messages: Belongs to the UPF0236 family.

273068:TTE RS00960
gene id: 273068:TTE_RS00960
uniprot id: Q8RD52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

273068:TTE RS10185
gene id: 273068:TTE_RS10185
uniprot id: Q8R885
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

273068:TTE RS01835
gene id: 273068:TTE_RS01835
uniprot id: Q8RCN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

273068:TTE RS02605
gene id: 273068:TTE_RS02605
uniprot id: Q8RC90
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

273068:TTE RS11800
gene id: 273068:TTE_RS11800
uniprot id: Q8R7E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

273068:TTE RS06960
gene id: 273068:TTE_RS06960
uniprot id: Q8R9X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

273068:TTE RS06725
gene id: 273068:TTE_RS06725
uniprot id: Q8RA22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

273068:TTE RS11220
gene id: 273068:TTE_RS11220
uniprot id: Q8R5P9
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

273068:TTE RS00855
gene id: 273068:TTE_RS00855
uniprot id: Q8RD73
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

273068:TTE RS04330
gene id: 273068:TTE_RS04330
uniprot id: Q8RBC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

273068:TTE RS01185
gene id: 273068:TTE_RS01185
uniprot id: Q8RD07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).

273068:TTE RS08505
gene id: 273068:TTE_RS08505
uniprot id: Q8R957
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

273068:TTE RS08470
gene id: 273068:TTE_RS08470
uniprot id: Q8R964
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

273068:TTE RS10490
gene id: 273068:TTE_RS10490
uniprot id: Q8R831
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

273068:TTE RS08115
gene id: 273068:TTE_RS08115
uniprot id: Q8R9C0
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS03895
gene id: 273068:TTE_RS03895
uniprot id: Q8RBK1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

273068:TTE RS04870
gene id: 273068:TTE_RS04870
uniprot id: Q8RB16
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

273068:TTE RS12735
gene id: 273068:TTE_RS12735
uniprot id: Q8R6V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

273068:TTE RS07225
gene id: 273068:TTE_RS07225
uniprot id: Q8R9S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

273068:TTE RS01215
gene id: 273068:TTE_RS01215
uniprot id: Q8RD02
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

273068:TTE RS08460
gene id: 273068:TTE_RS08460
uniprot id: Q8R966
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

273068:TTE RS11385
gene id: 273068:TTE_RS11385
uniprot id: Q8R7M3
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

273068:TTE RS04165
gene id: 273068:TTE_RS04165
uniprot id: Q8RBF0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

273068:TTE RS07480
gene id: 273068:TTE_RS07480
uniprot id: Q8R9N6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-65 and Arg-68) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

273068:TTE RS03865
gene id: 273068:TTE_RS03865
uniprot id: Q8RBK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

273068:TTE RS11500
gene id: 273068:TTE_RS11500
uniprot id: Q8R7K2
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS06995
gene id: 273068:TTE_RS06995
uniprot id: Q8R9W9
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein (By similarity).

273068:TTE RS04185
gene id: 273068:TTE_RS04185
uniprot id: Q8RBE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

273068:TTE RS08850
gene id: 273068:TTE_RS08850
uniprot id: Q8R8Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

273068:TTE RS03980
gene id: 273068:TTE_RS03980
uniprot id: Q8RBI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

273068:TTE RS02280
gene id: 273068:TTE_RS02280
uniprot id: Q8RCF1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

273068:TTE RS11960
gene id: 273068:TTE_RS11960
uniprot id: Q8R7B7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

273068:TTE RS10450
gene id: 273068:TTE_RS10450
uniprot id: Q8R837
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

273068:TTE RS12655
gene id: 273068:TTE_RS12655
uniprot id: Q8R6X1
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

273068:TTE RS11390
gene id: 273068:TTE_RS11390
uniprot id: Q8R7M2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

273068:TTE RS03065
gene id: 273068:TTE_RS03065
uniprot id: Q8RC17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

273068:TTE RS08625
gene id: 273068:TTE_RS08625
uniprot id: Q8R933
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

273068:TTE RS11780
gene id: 273068:TTE_RS11780
uniprot id: Q8R7F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

273068:TTE RS03870
gene id: 273068:TTE_RS03870
uniprot id: Q8RBK6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

273068:TTE RS00415
gene id: 273068:TTE_RS00415
uniprot id: Q8R5V1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

273068:TTE RS07930
gene id: 273068:TTE_RS07930
uniprot id: Q8R9F4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

273068:TTE RS00105
gene id: 273068:TTE_RS00105
uniprot id: Q8RDJ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

273068:TTE RS06920
gene id: 273068:TTE_RS06920
uniprot id: Q8R9Y2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

273068:TTE RS11935
gene id: 273068:TTE_RS11935
uniprot id: Q8R7C2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

273068:TTE RS11900
gene id: 273068:TTE_RS11900
uniprot id: Q8R7C8
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

273068:TTE RS08645
gene id: 273068:TTE_RS08645
uniprot id: Q8R929
names: Similarity
messages: Belongs to the manganese catalase family.

273068:TTE RS05435
gene id: 273068:TTE_RS05435
uniprot id: Q8RAR3
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS04160
gene id: 273068:TTE_RS04160
uniprot id: Q8RBF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

273068:TTE RS06265
gene id: 273068:TTE_RS06265
uniprot id: Q8RAB0
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

273068:TTE RS11415
gene id: 273068:TTE_RS11415
uniprot id: Q8R7L7
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

273068:TTE RS07130
gene id: 273068:TTE_RS07130
uniprot id: Q8R9U4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

273068:TTE RS06730
gene id: 273068:TTE_RS06730
uniprot id: Q8RA21
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

273068:TTE RS07185
gene id: 273068:TTE_RS07185
uniprot id: Q8R5S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

273068:TTE RS07005
gene id: 273068:TTE_RS07005
uniprot id: Q8R9W7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

273068:TTE RS04320
gene id: 273068:TTE_RS04320
uniprot id: Q8RBC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

273068:TTE RS13190
gene id: 273068:TTE_RS13190
uniprot id: Q8R6L7
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

273068:TTE RS07030
gene id: 273068:TTE_RS07030
uniprot id: Q8R9W2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

273068:TTE RS06845
gene id: 273068:TTE_RS06845
uniprot id: Q8R9Z7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

273068:TTE RS00405
gene id: 273068:TTE_RS00405
uniprot id: Q8R5V2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

273068:TTE RS01005
gene id: 273068:TTE_RS01005
uniprot id: Q8RD42
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS10690
gene id: 273068:TTE_RS10690
uniprot id: Q8R7Z5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

273068:TTE RS07545
gene id: 273068:TTE_RS07545
uniprot id: Q8R9M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

273068:TTE RS09110
gene id: 273068:TTE_RS09110
uniprot id: Q8R8U1
names: Similarity
messages: Belongs to the universal stress protein A family.

273068:TTE RS09670
gene id: 273068:TTE_RS09670
uniprot id: Q8R8I3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

273068:TTE RS06380
gene id: 273068:TTE_RS06380
uniprot id: Q8RA90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

273068:TTE RS03815
gene id: 273068:TTE_RS03815
uniprot id: Q8RBL8
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.
messages: Hydrolyzes kojibiose in the presence of an inorganic phosphoric acid to form D-glucose and beta-D-glucose-1-phosphoric acid.

273068:TTE RS10060
gene id: 273068:TTE_RS10060
uniprot id: Q8R8A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Cytoplasm

273068:TTE RS04905
gene id: 273068:TTE_RS04905
uniprot id: Q8RB10
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

273068:TTE RS07535
gene id: 273068:TTE_RS07535
uniprot id: Q8R9M6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

273068:TTE RS04865
gene id: 273068:TTE_RS04865
uniprot id: Q8RB17
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

273068:TTE RS02550
gene id: 273068:TTE_RS02550
uniprot id: Q8RCA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

273068:TTE RS06905
gene id: 273068:TTE_RS06905
uniprot id: Q8R9Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

273068:TTE RS00660
gene id: 273068:TTE_RS00660
uniprot id: Q8RDA9
names: Similarity
messages: Belongs to the HupF/HypC family.

273068:TTE RS02485
gene id: 273068:TTE_RS02485
uniprot id: Q8RCB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

273068:TTE RS05600
gene id: 273068:TTE_RS05600
uniprot id: Q8RAN4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

273068:TTE RS09275
gene id: 273068:TTE_RS09275
uniprot id: Q8R8Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS04620
gene id: 273068:TTE_RS04620
uniprot id: Q8RB64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

273068:TTE RS07065
gene id: 273068:TTE_RS07065
uniprot id: Q8R9V5
names: Function
names: Similarity
messages: Belongs to the FapR family.
messages: Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.

273068:TTE RS10875
gene id: 273068:TTE_RS10875
uniprot id: Q8R7W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12 (By similarity).

273068:TTE RS00615
gene id: 273068:TTE_RS00615
uniprot id: Q8RDB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

273068:TTE RS10200
gene id: 273068:TTE_RS10200
uniprot id: P58877
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

273068:TTE RS07630
gene id: 273068:TTE_RS07630
uniprot id: Q8R9K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

273068:TTE RS10975
gene id: 273068:TTE_RS10975
uniprot id: Q8R7U8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.

273068:TTE RS01095
gene id: 273068:TTE_RS01095
uniprot id: Q8RD25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS10790
gene id: 273068:TTE_RS10790
uniprot id: Q8R7Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).

273068:TTE RS03505
gene id: 273068:TTE_RS03505
uniprot id: Q8RBS8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

273068:TTE RS03070
gene id: 273068:TTE_RS03070
uniprot id: Q8RC16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

273068:TTE RS08615
gene id: 273068:TTE_RS08615
uniprot id: Q8R935
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

273068:TTE RS12090
gene id: 273068:TTE_RS12090
uniprot id: Q8R792
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

273068:TTE RS06835
gene id: 273068:TTE_RS06835
uniprot id: Q8R9Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

273068:TTE RS02265
gene id: 273068:TTE_RS02265
uniprot id: Q8RCF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

273068:TTE RS12170
gene id: 273068:TTE_RS12170
uniprot id: Q8R778
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

273068:TTE RS02365
gene id: 273068:TTE_RS02365
uniprot id: Q8RCD7
names: Similarity
messages: Belongs to the bacterial flagellin family.

273068:TTE RS13135
gene id: 273068:TTE_RS13135
uniprot id: Q8R6M8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

273068:TTE RS04340
gene id: 273068:TTE_RS04340
uniprot id: Q8RBB8
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

273068:TTE RS08905
gene id: 273068:TTE_RS08905
uniprot id: Q8R8X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

273068:TTE RS06090
gene id: 273068:TTE_RS06090
uniprot id: Q8RAE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

273068:TTE RS10915
gene id: 273068:TTE_RS10915
uniprot id: Q8R7W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

273068:TTE RS07390
gene id: 273068:TTE_RS07390
uniprot id: Q8R9Q3
names: Similarity
messages: Belongs to the peptidase S9C family.

273068:TTE RS10940
gene id: 273068:TTE_RS10940
uniprot id: Q8R7V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

273068:TTE RS00175
gene id: 273068:TTE_RS00175
uniprot id: Q8R6I7
names: Similarity
messages: Belongs to the UPF0236 family.

273068:TTE RS06460
gene id: 273068:TTE_RS06460
uniprot id: Q8RA74
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

273068:TTE RS03520
gene id: 273068:TTE_RS03520
uniprot id: Q8RBS5
names: Similarity
messages: Belongs to the CpsD/CapB family.

273068:TTE RS10880
gene id: 273068:TTE_RS10880
uniprot id: Q8R7W7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

273068:TTE RS02645
gene id: 273068:TTE_RS02645
uniprot id: Q8RC84
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

273068:TTE RS03425
gene id: 273068:TTE_RS03425
uniprot id: Q8RBU3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

273068:TTE RS02455
gene id: 273068:TTE_RS02455
uniprot id: Q8RCC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

273068:TTE RS07525
gene id: 273068:TTE_RS07525
uniprot id: Q8R9M8
names: Similarity
messages: Belongs to the TrpF family.

273068:TTE RS06900
gene id: 273068:TTE_RS06900
uniprot id: Q8R9Y6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

273068:TTE RS00320
gene id: 273068:TTE_RS00320
uniprot id: Q8RDG9
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

273068:TTE RS04315
gene id: 273068:TTE_RS04315
uniprot id: Q8RBC3
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

273068:TTE RS04685
gene id: 273068:TTE_RS04685
uniprot id: Q8RB51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

273068:TTE RS03085
gene id: 273068:TTE_RS03085
uniprot id: Q8RC13
names: Similarity
messages: Belongs to the EamA transporter family.

273068:TTE RS04940
gene id: 273068:TTE_RS04940
uniprot id: Q8R5T0
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.

273068:TTE RS10350
gene id: 273068:TTE_RS10350
uniprot id: Q8R858
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273068:TTE RS06890
gene id: 273068:TTE_RS06890
uniprot id: Q8R9Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

273068:TTE RS09300
gene id: 273068:TTE_RS09300
uniprot id: Q8R8Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

273068:TTE RS07040
gene id: 273068:TTE_RS07040
uniprot id: Q8R9W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

273068:TTE RS01420
gene id: 273068:TTE_RS01420
uniprot id: Q8RCW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

273068:TTE RS08970
gene id: 273068:TTE_RS08970
uniprot id: Q8R8W5
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

273068:TTE RS03590
gene id: 273068:TTE_RS03590
uniprot id: Q8RBR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.

273068:TTE RS06015
gene id: 273068:TTE_RS06015
uniprot id: Q8RAF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

273068:TTE RS08335
gene id: 273068:TTE_RS08335
uniprot id: Q8R985
names: Subcellular Location Annotation
messages: Cytoplasm

273068:TTE RS10155
gene id: 273068:TTE_RS10155
uniprot id: Q8R890
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family.
messages: Cytoplasm
messages: In contrast to other XerC proteins, it has a much longer N-terminal part.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

273068:TTE RS07625
gene id: 273068:TTE_RS07625
uniprot id: Q8R9K9
names: Similarity
messages: Belongs to the YggT family.

273068:TTE RS06675
gene id: 273068:TTE_RS06675
uniprot id: Q8RA33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

273068:TTE RS11345
gene id: 273068:TTE_RS11345
uniprot id: Q8R7N1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

273068:TTE RS11420
gene id: 273068:TTE_RS11420
uniprot id: Q8R7L6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

273068:TTE RS05710
gene id: 273068:TTE_RS05710
uniprot id: Q8RAL3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

273068:TTE RS04825
gene id: 273068:TTE_RS04825
uniprot id: Q8RB25
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

273068:TTE RS10500
gene id: 273068:TTE_RS10500
uniprot id: Q8R829
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

273068:TTE RS11520
gene id: 273068:TTE_RS11520
uniprot id: Q8R7J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

273068:TTE RS11320
gene id: 273068:TTE_RS11320
uniprot id: Q8R7N6
names: Similarity
messages: Belongs to the SfsA family.

273068:TTE RS11905
gene id: 273068:TTE_RS11905
uniprot id: Q8R7C7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

273068:TTE RS05545
gene id: 273068:TTE_RS05545
uniprot id: Q8RAP3
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.
messages: Belongs to the radical SAM superfamily. NifB family.

273068:TTE RS05850
gene id: 273068:TTE_RS05850
uniprot id: Q8RAI8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

273068:TTE RS11555
gene id: 273068:TTE_RS11555
uniprot id: Q8R7J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS05190
gene id: 273068:TTE_RS05190
uniprot id: Q8R6I7
names: Similarity
messages: Belongs to the UPF0236 family.

273068:TTE RS00450
gene id: 273068:TTE_RS00450
uniprot id: Q8RDE9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

273068:TTE RS04610
gene id: 273068:TTE_RS04610
uniprot id: Q8RB66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

273068:TTE RS04585
gene id: 273068:TTE_RS04585
uniprot id: Q8RB71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

273068:TTE RS13165
gene id: 273068:TTE_RS13165
uniprot id: Q8R6M2
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

273068:TTE RS06500
gene id: 273068:TTE_RS06500
uniprot id: Q8RA67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

273068:TTE RS00210
gene id: 273068:TTE_RS00210
uniprot id: Q8RDI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

273068:TTE RS02130
gene id: 273068:TTE_RS02130
uniprot id: Q8RCI3
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

273068:TTE RS02150
gene id: 273068:TTE_RS02150
uniprot id: Q8RCH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

273068:TTE RS06695
gene id: 273068:TTE_RS06695
uniprot id: Q8RA29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

273068:TTE RS01615
gene id: 273068:TTE_RS01615
uniprot id: Q8RCS6
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

273068:TTE RS01375
gene id: 273068:TTE_RS01375
uniprot id: Q8RCX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

273068:TTE RS10895
gene id: 273068:TTE_RS10895
uniprot id: Q8R7W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

273068:TTE RS00765
gene id: 273068:TTE_RS00765
uniprot id: Q8RD91
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

273068:TTE RS02600
gene id: 273068:TTE_RS02600
uniprot id: Q8RC91
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

273068:TTE RS04745
gene id: 273068:TTE_RS04745
uniprot id: Q8RB39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

273068:TTE RS02770
gene id: 273068:TTE_RS02770
uniprot id: Q8RC64
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

273068:TTE RS05385
gene id: 273068:TTE_RS05385
uniprot id: Q8RAS2
names: Similarity
messages: Belongs to the IMPACT family.

273068:TTE RS13210
gene id: 273068:TTE_RS13210
uniprot id: Q8R6L3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

273068:TTE RS04880
gene id: 273068:TTE_RS04880
uniprot id: Q8RB14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

273068:TTE RS11855
gene id: 273068:TTE_RS11855
uniprot id: Q8R7D7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

273068:TTE RS07485
gene id: 273068:TTE_RS07485
uniprot id: Q8R9N5
names: Similarity
messages: Belongs to the UPF0047 family.

273068:TTE RS02805
gene id: 273068:TTE_RS02805
uniprot id: Q8RC57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

273068:TTE RS04875
gene id: 273068:TTE_RS04875
uniprot id: Q8RB15
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

273068:TTE RS07370
gene id: 273068:TTE_RS07370
uniprot id: Q8R9Q6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

273068:TTE RS11835
gene id: 273068:TTE_RS11835
uniprot id: Q8R7E1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

273068:TTE RS10905
gene id: 273068:TTE_RS10905
uniprot id: Q8R7W2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

273068:TTE RS09265
gene id: 273068:TTE_RS09265
uniprot id: Q8R8R1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

273068:TTE RS01895
gene id: 273068:TTE_RS01895
uniprot id: Q8RCM8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

273068:TTE RS04425
gene id: 273068:TTE_RS04425
uniprot id: Q8RBA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

273068:TTE RS10630
gene id: 273068:TTE_RS10630
uniprot id: Q8R807
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

273068:TTE RS03335
gene id: 273068:TTE_RS03335
uniprot id: Q8RBW4
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

273068:TTE RS11005
gene id: 273068:TTE_RS11005
uniprot id: Q8R7U2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

273068:TTE RS10175
gene id: 273068:TTE_RS10175
uniprot id: Q8R5Q5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

273068:TTE RS04100
gene id: 273068:TTE_RS04100
uniprot id: Q8RBG3
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.

273068:TTE RS04645
gene id: 273068:TTE_RS04645
uniprot id: Q8RB59
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

273068:TTE RS05785
gene id: 273068:TTE_RS05785
uniprot id: Q8RAJ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

273068:TTE RS07170
gene id: 273068:TTE_RS07170
uniprot id: Q8R9T6
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

273068:TTE RS12950
gene id: 273068:TTE_RS12950
uniprot id: Q8R6R4
names: Similarity
messages: Belongs to the peptidase U62 family.

273068:TTE RS03095
gene id: 273068:TTE_RS03095
uniprot id: Q8RC11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS10055
gene id: 273068:TTE_RS10055
uniprot id: Q8R8A7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

273068:TTE RS08655
gene id: 273068:TTE_RS08655
uniprot id: Q8R927
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

273068:TTE RS01470
gene id: 273068:TTE_RS01470
uniprot id: Q8RCV2
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS07600
gene id: 273068:TTE_RS07600
uniprot id: Q8R9L4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.

273068:TTE RS12850
gene id: 273068:TTE_RS12850
uniprot id: Q8R6T2
names: Similarity
messages: Belongs to the CapA family.

273068:TTE RS10910
gene id: 273068:TTE_RS10910
uniprot id: Q8R7W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

273068:TTE RS10180
gene id: 273068:TTE_RS10180
uniprot id: Q8R886
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

273068:TTE RS00655
gene id: 273068:TTE_RS00655
uniprot id: Q8RDB0
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Belongs to the carbamoyltransferase HypF family.

273068:TTE RS06170
gene id: 273068:TTE_RS06170
uniprot id: Q8RAC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

273068:TTE RS01430
gene id: 273068:TTE_RS01430
uniprot id: Q8RCW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

273068:TTE RS09330
gene id: 273068:TTE_RS09330
uniprot id: Q8R8P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

273068:TTE RS05725
gene id: 273068:TTE_RS05725
uniprot id: Q8RAL0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

273068:TTE RS09445
gene id: 273068:TTE_RS09445
uniprot id: Q8R8M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

273068:TTE RS05310
gene id: 273068:TTE_RS05310
uniprot id: Q8RAT5
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

273068:TTE RS01810
gene id: 273068:TTE_RS01810
uniprot id: Q8RCP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

273068:TTE RS02820
gene id: 273068:TTE_RS02820
uniprot id: Q8RC54
names: Cofactor
names: Similarity
messages: Belongs to the GARS family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

273068:TTE RS10870
gene id: 273068:TTE_RS10870
uniprot id: Q8R7W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

273068:TTE RS04385
gene id: 273068:TTE_RS04385
uniprot id: Q8RBA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

273068:TTE RS03615
gene id: 273068:TTE_RS03615
uniprot id: Q8RBQ8
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS02810
gene id: 273068:TTE_RS02810
uniprot id: Q8RC56
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273068:TTE RS08100
gene id: 273068:TTE_RS08100
uniprot id: Q8R9C3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

273068:TTE RS12100
gene id: 273068:TTE_RS12100
uniprot id: Q8R790
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS05945
gene id: 273068:TTE_RS05945
uniprot id: Q8R5S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

273068:TTE RS10775
gene id: 273068:TTE_RS10775
uniprot id: Q8R7Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

273068:TTE RS10935
gene id: 273068:TTE_RS10935
uniprot id: Q8R7V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

273068:TTE RS00410
gene id: 273068:TTE_RS00410
uniprot id: Q8RDF6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

273068:TTE RS02895
gene id: 273068:TTE_RS02895
uniprot id: Q8RC39
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

273068:TTE RS00785
gene id: 273068:TTE_RS00785
uniprot id: Q8RD87
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS13270
gene id: 273068:TTE_RS13270
uniprot id: Q8R6K3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

273068:TTE RS06450
gene id: 273068:TTE_RS06450
uniprot id: Q8RA76
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

273068:TTE RS03830
gene id: 273068:TTE_RS03830
uniprot id: Q8RBL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS10805
gene id: 273068:TTE_RS10805
uniprot id: Q8R7Y2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

273068:TTE RS00275
gene id: 273068:TTE_RS00275
uniprot id: Q8R5V5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

273068:TTE RS06530
gene id: 273068:TTE_RS06530
uniprot id: Q8RA61
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

273068:TTE RS06630
gene id: 273068:TTE_RS06630
uniprot id: Q8RA42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

273068:TTE RS12665
gene id: 273068:TTE_RS12665
uniprot id: Q8R6W9
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

273068:TTE RS07570
gene id: 273068:TTE_RS07570
uniprot id: Q8R9M0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

273068:TTE RS08630
gene id: 273068:TTE_RS08630
uniprot id: Q8R932
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

273068:TTE RS06315
gene id: 273068:TTE_RS06315
uniprot id: Q8RAA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

273068:TTE RS12645
gene id: 273068:TTE_RS12645
uniprot id: Q8R6X3
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

273068:TTE RS03015
gene id: 273068:TTE_RS03015
uniprot id: Q8RC26
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

273068:TTE RS06895
gene id: 273068:TTE_RS06895
uniprot id: Q8R9Y7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

273068:TTE RS11670
gene id: 273068:TTE_RS11670
uniprot id: Q8R7H1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

273068:TTE RS01730
gene id: 273068:TTE_RS01730
uniprot id: Q8RCQ6
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

273068:TTE RS03060
gene id: 273068:TTE_RS03060
uniprot id: Q8RC18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

273068:TTE RS04605
gene id: 273068:TTE_RS04605
uniprot id: Q8RB67
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

273068:TTE RS04225
gene id: 273068:TTE_RS04225
uniprot id: Q8R6I2
names: Similarity
messages: Belongs to the UPF0236 family.

273068:TTE RS08700
gene id: 273068:TTE_RS08700
uniprot id: Q8R918
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

273068:TTE RS09425
gene id: 273068:TTE_RS09425
uniprot id: Q8R8M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

273068:TTE RS02585
gene id: 273068:TTE_RS02585
uniprot id: Q8RC94
names: Similarity
messages: Belongs to the MotB family.

273068:TTE RS00420
gene id: 273068:TTE_RS00420
uniprot id: Q8RDF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

273068:TTE RS04420
gene id: 273068:TTE_RS04420
uniprot id: Q8RBA2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

273068:TTE RS11335
gene id: 273068:TTE_RS11335
uniprot id: Q8R7N3
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

273068:TTE RS00595
gene id: 273068:TTE_RS00595
uniprot id: Q8RDC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

273068:TTE RS12515
gene id: 273068:TTE_RS12515
uniprot id: Q8R710
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

273068:TTE RS02775
gene id: 273068:TTE_RS02775
uniprot id: Q8RC63
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

273068:TTE RS00585
gene id: 273068:TTE_RS00585
uniprot id: Q8RDC4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

273068:TTE RS08040
gene id: 273068:TTE_RS08040
uniprot id: Q8R9D4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

273068:TTE RS06790
gene id: 273068:TTE_RS06790
uniprot id: Q8RA08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

273068:TTE RS02360
gene id: 273068:TTE_RS02360
uniprot id: Q8RCD8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

273068:TTE RS06825
gene id: 273068:TTE_RS06825
uniprot id: Q8RA01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

273068:TTE RS06720
gene id: 273068:TTE_RS06720
uniprot id: Q8RA23
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.

273068:TTE RS02435
gene id: 273068:TTE_RS02435
uniprot id: Q8RCC4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

273068:TTE RS11065
gene id: 273068:TTE_RS11065
uniprot id: Q8R7T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

273068:TTE RS07520
gene id: 273068:TTE_RS07520
uniprot id: Q8R9M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

273068:TTE RS10980
gene id: 273068:TTE_RS10980
uniprot id: Q8R7U7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

273068:TTE RS01735
gene id: 273068:TTE_RS01735
uniprot id: Q8RCQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

273068:TTE RS09450
gene id: 273068:TTE_RS09450
uniprot id: Q8R8M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.

273068:TTE RS11380
gene id: 273068:TTE_RS11380
uniprot id: Q8R7M4
names: Similarity
messages: Belongs to the GerABKA family.

273068:TTE RS05835
gene id: 273068:TTE_RS05835
uniprot id: Q8R6I5
names: Function
messages: Involved in the transposition of the insertion sequence.

273068:TTE RS04580
gene id: 273068:TTE_RS04580
uniprot id: Q8RB72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

273068:TTE RS03075
gene id: 273068:TTE_RS03075
uniprot id: Q8RC15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

273068:TTE RS07500
gene id: 273068:TTE_RS07500
uniprot id: Q8R9N2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

273068:TTE RS11480
gene id: 273068:TTE_RS11480
uniprot id: Q8R7K6
names: Similarity
messages: Belongs to the EamA transporter family.

273068:TTE RS00610
gene id: 273068:TTE_RS00610
uniprot id: Q8RDB9
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

273068:TTE RS04040
gene id: 273068:TTE_RS04040
uniprot id: Q8RBH4
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

273068:TTE RS11755
gene id: 273068:TTE_RS11755
uniprot id: Q8R7F4
names: Subcellular Location Annotation
messages: Cell membrane

273068:TTE RS06485
gene id: 273068:TTE_RS06485
uniprot id: Q8R5S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

273068:TTE RS12135
gene id: 273068:TTE_RS12135
uniprot id: Q8R783
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS09235
gene id: 273068:TTE_RS09235
uniprot id: Q8R8R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

273068:TTE RS01480
gene id: 273068:TTE_RS01480
uniprot id: Q8RCV0
names: Similarity
messages: Belongs to the UPF0309 family.

273068:TTE RS11110
gene id: 273068:TTE_RS11110
uniprot id: Q8R7S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

273068:TTE RS09170
gene id: 273068:TTE_RS09170
uniprot id: Q8R8T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS00520
gene id: 273068:TTE_RS00520
uniprot id: Q8RDD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

273068:TTE RS03130
gene id: 273068:TTE_RS03130
uniprot id: Q8RC02
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

273068:TTE RS00720
gene id: 273068:TTE_RS00720
uniprot id: Q8RD97
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS10615
gene id: 273068:TTE_RS10615
uniprot id: Q8R810
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

273068:TTE RS12505
gene id: 273068:TTE_RS12505
uniprot id: Q8R712
names: Similarity
messages: Belongs to the peptidase S41A family.

273068:TTE RS02915
gene id: 273068:TTE_RS02915
uniprot id: Q8RC36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS12855
gene id: 273068:TTE_RS12855
uniprot id: Q8R6T1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

273068:TTE RS07880
gene id: 273068:TTE_RS07880
uniprot id: Q8R9G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane

273068:TTE RS06855
gene id: 273068:TTE_RS06855
uniprot id: Q8R9Z5
names: Similarity
messages: Belongs to the FlgD family.

273068:TTE RS02380
gene id: 273068:TTE_RS02380
uniprot id: Q8RCD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

273068:TTE RS10170
gene id: 273068:TTE_RS10170
uniprot id: Q8R887
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

273068:TTE RS06080
gene id: 273068:TTE_RS06080
uniprot id: Q8RAE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

273068:TTE RS10770
gene id: 273068:TTE_RS10770
uniprot id: Q8R7Y9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

273068:TTE RS06810
gene id: 273068:TTE_RS06810
uniprot id: Q8RA04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

273068:TTE RS03500
gene id: 273068:TTE_RS03500
uniprot id: Q8RBS9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

273068:TTE RS09465
gene id: 273068:TTE_RS09465
uniprot id: Q8R8M1
names: Similarity
messages: Belongs to the peptidase S41A family.

273068:TTE RS07615
gene id: 273068:TTE_RS07615
uniprot id: Q8R9L1
names: Subcellular Location Annotation
messages: Cytoplasm

273068:TTE RS06610
gene id: 273068:TTE_RS06610
uniprot id: Q8RA46
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

273068:TTE RS02010
gene id: 273068:TTE_RS02010
uniprot id: Q8RCK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

273068:TTE RS08705
gene id: 273068:TTE_RS08705
uniprot id: Q8R917
names: Similarity
messages: Belongs to the glycosyl hydrolase 15 family.

273068:TTE RS00045
gene id: 273068:TTE_RS00045
uniprot id: Q8RDK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

273068:TTE RS01915
gene id: 273068:TTE_RS01915
uniprot id: Q8RCM4
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS11510
gene id: 273068:TTE_RS11510
uniprot id: Q8R7K0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

273068:TTE RS12035
gene id: 273068:TTE_RS12035
uniprot id: Q8R7A2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

273068:TTE RS08720
gene id: 273068:TTE_RS08720
uniprot id: Q8R914
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

273068:TTE RS05610
gene id: 273068:TTE_RS05610
uniprot id: Q8RAN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

273068:TTE RS02535
gene id: 273068:TTE_RS02535
uniprot id: Q8RCA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

273068:TTE RS01225
gene id: 273068:TTE_RS01225
uniprot id: P58965
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

273068:TTE RS10190
gene id: 273068:TTE_RS10190
uniprot id: Q8R884
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

273068:TTE RS09035
gene id: 273068:TTE_RS09035
uniprot id: Q8R5R2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

273068:TTE RS09625
gene id: 273068:TTE_RS09625
uniprot id: Q8R8J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

273068:TTE RS12745
gene id: 273068:TTE_RS12745
uniprot id: Q8R6V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

273068:TTE RS09650
gene id: 273068:TTE_RS09650
uniprot id: Q8R8I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

273068:TTE RS05630
gene id: 273068:TTE_RS05630
uniprot id: Q8RAM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

273068:TTE RS04760
gene id: 273068:TTE_RS04760
uniprot id: Q8RB37
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

273068:TTE RS06985
gene id: 273068:TTE_RS06985
uniprot id: Q8R9X1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

273068:TTE RS01830
gene id: 273068:TTE_RS01830
uniprot id: Q8RCN9
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

273068:TTE RS01525
gene id: 273068:TTE_RS01525
uniprot id: Q8RCU2
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

273068:TTE RS10645
gene id: 273068:TTE_RS10645
uniprot id: Q8R804
names: Similarity
messages: Belongs to the ThiD family.

273068:TTE RS00465
gene id: 273068:TTE_RS00465
uniprot id: Q8RDE7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

273068:TTE RS10570
gene id: 273068:TTE_RS10570
uniprot id: Q8R817
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

273068:TTE RS08095
gene id: 273068:TTE_RS08095
uniprot id: Q8R9C4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

273068:TTE RS06490
gene id: 273068:TTE_RS06490
uniprot id: Q8RA69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

273068:TTE RS13255
gene id: 273068:TTE_RS13255
uniprot id: Q8R6K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration (By similarity).
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins (By similarity).

273068:TTE RS01760
gene id: 273068:TTE_RS01760
uniprot id: Q8RCQ2
names: Similarity
messages: Belongs to the Fur family.

273068:TTE RS12105
gene id: 273068:TTE_RS12105
uniprot id: Q8R789
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS04085
gene id: 273068:TTE_RS04085
uniprot id: Q8R6I7
names: Similarity
messages: Belongs to the UPF0236 family.

273068:TTE RS07790
gene id: 273068:TTE_RS07790
uniprot id: Q8R9I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

273068:TTE RS07330
gene id: 273068:TTE_RS07330
uniprot id: Q8R9R3
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

273068:TTE RS08475
gene id: 273068:TTE_RS08475
uniprot id: Q8R963
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

273068:TTE RS07775
gene id: 273068:TTE_RS07775
uniprot id: Q8R9I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

273068:TTE RS00695
gene id: 273068:TTE_RS00695
uniprot id: Q8RDA2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

273068:TTE RS04850
gene id: 273068:TTE_RS04850
uniprot id: Q8RB20
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273068:TTE RS10400
gene id: 273068:TTE_RS10400
uniprot id: Q8R848
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS04395
gene id: 273068:TTE_RS04395
uniprot id: Q8RBA7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

273068:TTE RS08820
gene id: 273068:TTE_RS08820
uniprot id: Q8R8Z4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273068:TTE RS00010
gene id: 273068:TTE_RS00010
uniprot id: Q8RDL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

273068:TTE RS12000
gene id: 273068:TTE_RS12000
uniprot id: Q8R7A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

273068:TTE RS08045
gene id: 273068:TTE_RS08045
uniprot id: Q8R9D3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

273068:TTE RS12945
gene id: 273068:TTE_RS12945
uniprot id: Q8R6R5
names: Similarity
messages: Belongs to the peptidase S51 family.

273068:TTE RS02195
gene id: 273068:TTE_RS02195
uniprot id: Q8RCG9
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS04735
gene id: 273068:TTE_RS04735
uniprot id: Q8RB41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

273068:TTE RS11000
gene id: 273068:TTE_RS11000
uniprot id: Q8R7U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

273068:TTE RS10550
gene id: 273068:TTE_RS10550
uniprot id: Q8R821
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PpaX family.

273068:TTE RS04795
gene id: 273068:TTE_RS04795
uniprot id: Q8RB31
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

273068:TTE RS02885
gene id: 273068:TTE_RS02885
uniprot id: Q8RC41
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

273068:TTE RS08340
gene id: 273068:TTE_RS08340
uniprot id: Q8R6I7
names: Similarity
messages: Belongs to the UPF0236 family.

273068:TTE RS07090
gene id: 273068:TTE_RS07090
uniprot id: Q8R9V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

273068:TTE RS04175
gene id: 273068:TTE_RS04175
uniprot id: Q8RBE8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

273068:TTE RS05605
gene id: 273068:TTE_RS05605
uniprot id: Q8RAN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

273068:TTE RS05930
gene id: 273068:TTE_RS05930
uniprot id: Q8R6I7
names: Similarity
messages: Belongs to the UPF0236 family.

273068:TTE RS11875
gene id: 273068:TTE_RS11875
uniprot id: Q8R7D3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

273068:TTE RS01275
gene id: 273068:TTE_RS01275
uniprot id: Q8RCZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

273068:TTE RS07085
gene id: 273068:TTE_RS07085
uniprot id: Q8R9V3
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

273068:TTE RS05975
gene id: 273068:TTE_RS05975
uniprot id: Q8RAG7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273068:TTE RS03875
gene id: 273068:TTE_RS03875
uniprot id: Q8RBK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

273068:TTE RS10845
gene id: 273068:TTE_RS10845
uniprot id: Q8R7X4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

273068:TTE RS12750
gene id: 273068:TTE_RS12750
uniprot id: Q8R6V1
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS01550
gene id: 273068:TTE_RS01550
uniprot id: Q8RCT7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

273068:TTE RS09280
gene id: 273068:TTE_RS09280
uniprot id: Q8R8Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS05915
gene id: 273068:TTE_RS05915
uniprot id: Q8RAH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

273068:TTE RS03720
gene id: 273068:TTE_RS03720
uniprot id: Q8RBN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

273068:TTE RS07220
gene id: 273068:TTE_RS07220
uniprot id: Q8R9S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

273068:TTE RS00385
gene id: 273068:TTE_RS00385
uniprot id: Q8RDF7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

273068:TTE RS03205
gene id: 273068:TTE_RS03205
uniprot id: Q8RBY7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

273068:TTE RS10220
gene id: 273068:TTE_RS10220
uniprot id: Q8R880
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

273068:TTE RS11340
gene id: 273068:TTE_RS11340
uniprot id: Q8R7N2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

273068:TTE RS08360
gene id: 273068:TTE_RS08360
uniprot id: Q8R980
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

273068:TTE RS10785
gene id: 273068:TTE_RS10785
uniprot id: Q8R7Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

273068:TTE RS06205
gene id: 273068:TTE_RS06205
uniprot id: Q8RAC1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

273068:TTE RS07580
gene id: 273068:TTE_RS07580
uniprot id: Q8R9L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).

273068:TTE RS01655
gene id: 273068:TTE_RS01655
uniprot id: Q8RCR8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

273068:TTE RS00525
gene id: 273068:TTE_RS00525
uniprot id: Q8RDD5
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS04690
gene id: 273068:TTE_RS04690
uniprot id: Q8RB50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

273068:TTE RS02955
gene id: 273068:TTE_RS02955
uniprot id: Q8RC28
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

273068:TTE RS00080
gene id: 273068:TTE_RS00080
uniprot id: Q8RDK4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

273068:TTE RS07145
gene id: 273068:TTE_RS07145
uniprot id: Q8R9U1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

273068:TTE RS10240
gene id: 273068:TTE_RS10240
uniprot id: Q8R876
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS05305
gene id: 273068:TTE_RS05305
uniprot id: Q8RAT6
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

273068:TTE RS02675
gene id: 273068:TTE_RS02675
uniprot id: Q8RC77
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

273068:TTE RS13145
gene id: 273068:TTE_RS13145
uniprot id: Q8R6M6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

273068:TTE RS08665
gene id: 273068:TTE_RS08665
uniprot id: Q8R925
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

273068:TTE RS04200
gene id: 273068:TTE_RS04200
uniprot id: Q8RBE3
names: Similarity
messages: Belongs to the NadC/ModD family.

273068:TTE RS06885
gene id: 273068:TTE_RS06885
uniprot id: Q8R9Y9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

273068:TTE RS10810
gene id: 273068:TTE_RS10810
uniprot id: Q8R7Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

273068:TTE RS10885
gene id: 273068:TTE_RS10885
uniprot id: Q8R7W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

273068:TTE RS13235
gene id: 273068:TTE_RS13235
uniprot id: Q8R6L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

273068:TTE RS09930
gene id: 273068:TTE_RS09930
uniprot id: Q8R8D1
names: Similarity
messages: Belongs to the GSP E family.

273068:TTE RS06175
gene id: 273068:TTE_RS06175
uniprot id: Q8RAC7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

273068:TTE RS04755
gene id: 273068:TTE_RS04755
uniprot id: Q8RB38
names: Similarity
messages: Belongs to the peptidase C56 family.

273068:TTE RS12820
gene id: 273068:TTE_RS12820
uniprot id: Q8R6T8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

273068:TTE RS11730
gene id: 273068:TTE_RS11730
uniprot id: Q8R7F9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

273068:TTE RS02440
gene id: 273068:TTE_RS02440
uniprot id: Q8RCC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS13225
gene id: 273068:TTE_RS13225
uniprot id: Q8R5P2
names: Similarity
messages: Belongs to the ParB family.

273068:TTE RS03900
gene id: 273068:TTE_RS03900
uniprot id: Q8RBK0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

273068:TTE RS02215
gene id: 273068:TTE_RS02215
uniprot id: Q8RCG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

273068:TTE RS06305
gene id: 273068:TTE_RS06305
uniprot id: Q8R5S7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

273068:TTE RS01245
gene id: 273068:TTE_RS01245
uniprot id: Q8RCZ6
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS08465
gene id: 273068:TTE_RS08465
uniprot id: Q8R965
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

273068:TTE RS06800
gene id: 273068:TTE_RS06800
uniprot id: Q8RA06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

273068:TTE RS06715
gene id: 273068:TTE_RS06715
uniprot id: Q8RA24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

273068:TTE RS10795
gene id: 273068:TTE_RS10795
uniprot id: Q8R7Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).

273068:TTE RS03845
gene id: 273068:TTE_RS03845
uniprot id: Q8RBL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS04900
gene id: 273068:TTE_RS04900
uniprot id: Q8RB11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

273068:TTE RS07785
gene id: 273068:TTE_RS07785
uniprot id: Q8R9I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

273068:TTE RS00865
gene id: 273068:TTE_RS00865
uniprot id: Q8RD71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

273068:TTE RS02945
gene id: 273068:TTE_RS02945
uniprot id: Q8RC30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

273068:TTE RS01605
gene id: 273068:TTE_RS01605
uniprot id: Q8RCS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YdjC deacetylase family.
messages: Homodimer.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

273068:TTE RS02615
gene id: 273068:TTE_RS02615
uniprot id: Q8R5U1
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

273068:TTE RS10530
gene id: 273068:TTE_RS10530
uniprot id: Q8R6I7
names: Similarity
messages: Belongs to the UPF0236 family.

273068:TTE RS04350
gene id: 273068:TTE_RS04350
uniprot id: Q8RBB6
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

273068:TTE RS05665
gene id: 273068:TTE_RS05665
uniprot id: Q8RAM1
names: Similarity
messages: Belongs to the RecJ family.

273068:TTE RS04180
gene id: 273068:TTE_RS04180
uniprot id: Q8RBE7
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

273068:TTE RS07695
gene id: 273068:TTE_RS07695
uniprot id: Q8R9J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

273068:TTE RS11945
gene id: 273068:TTE_RS11945
uniprot id: Q8R7C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

273068:TTE RS02245
gene id: 273068:TTE_RS02245
uniprot id: Q8RCF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

273068:TTE RS03195
gene id: 273068:TTE_RS03195
uniprot id: Q8RBY9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

273068:TTE RS08405
gene id: 273068:TTE_RS08405
uniprot id: Q8R974
names: Cofactor
messages: Binds 1 zinc ion per subunit.

273068:TTE RS02120
gene id: 273068:TTE_RS02120
uniprot id: Q8RCI5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

273068:TTE RS07725
gene id: 273068:TTE_RS07725
uniprot id: Q8R9J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

273068:TTE RS08495
gene id: 273068:TTE_RS08495
uniprot id: Q8R959
names: Similarity
messages: Belongs to the Fur family.

273068:TTE RS11170
gene id: 273068:TTE_RS11170
uniprot id: Q8R7Q9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

273068:TTE RS05620
gene id: 273068:TTE_RS05620
uniprot id: Q8RAN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

273068:TTE RS00995
gene id: 273068:TTE_RS00995
uniprot id: Q8RD44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

273068:TTE RS07245
gene id: 273068:TTE_RS07245
uniprot id: Q8R9S3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

273068:TTE RS13025
gene id: 273068:TTE_RS13025
uniprot id: Q8R6P9
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.
messages: Belongs to the radical SAM superfamily. NifB family.

273068:TTE RS09415
gene id: 273068:TTE_RS09415
uniprot id: Q8R8N1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

273068:TTE RS11440
gene id: 273068:TTE_RS11440
uniprot id: Q8R7L3
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

273068:TTE RS03455
gene id: 273068:TTE_RS03455
uniprot id: Q8RBT8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

273068:TTE RS04135
gene id: 273068:TTE_RS04135
uniprot id: Q8RBF6
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS09025
gene id: 273068:TTE_RS09025
uniprot id: Q8R8V8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

273068:TTE RS09635
gene id: 273068:TTE_RS09635
uniprot id: Q8R8J0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

273068:TTE RS03940
gene id: 273068:TTE_RS03940
uniprot id: Q8RBJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S8 family.
messages: Monomer.
messages: Serine protease with a broad substrate specificity.

273068:TTE RS01200
gene id: 273068:TTE_RS01200
uniprot id: Q8RD04
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS06215
gene id: 273068:TTE_RS06215
uniprot id: Q8RAB9
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

273068:TTE RS04005
gene id: 273068:TTE_RS04005
uniprot id: Q8RBI0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

273068:TTE RS03970
gene id: 273068:TTE_RS03970
uniprot id: Q8RBI7
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

273068:TTE RS11025
gene id: 273068:TTE_RS11025
uniprot id: Q8R7T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

273068:TTE RS01630
gene id: 273068:TTE_RS01630
uniprot id: Q8RCS3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

273068:TTE RS00215
gene id: 273068:TTE_RS00215
uniprot id: Q8RDI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

273068:TTE RS05990
gene id: 273068:TTE_RS05990
uniprot id: Q8RAG4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

273068:TTE RS08780
gene id: 273068:TTE_RS08780
uniprot id: Q8R903
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS10340
gene id: 273068:TTE_RS10340
uniprot id: Q8R860
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

273068:TTE RS06670
gene id: 273068:TTE_RS06670
uniprot id: Q8RA34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

273068:TTE RS05475
gene id: 273068:TTE_RS05475
uniprot id: Q8RAQ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

273068:TTE RS04285
gene id: 273068:TTE_RS04285
uniprot id: Q8RBC9
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

273068:TTE RS01265
gene id: 273068:TTE_RS01265
uniprot id: Q8RCZ2
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS08005
gene id: 273068:TTE_RS08005
uniprot id: Q8R9D9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

273068:TTE RS07115
gene id: 273068:TTE_RS07115
uniprot id: Q8R9U7
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

273068:TTE RS02385
gene id: 273068:TTE_RS02385
uniprot id: Q8RCD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

273068:TTE RS12360
gene id: 273068:TTE_RS12360
uniprot id: Q8R739
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

273068:TTE RS14325
gene id: 273068:TTE_RS14325
uniprot id: Q8R7Z6
names: Subcellular Location Annotation
messages: Cell membrane

273068:TTE RS08000
gene id: 273068:TTE_RS08000
uniprot id: Q8R9E0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

273068:TTE RS03340
gene id: 273068:TTE_RS03340
uniprot id: Q8RBW3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

273068:TTE RS01270
gene id: 273068:TTE_RS01270
uniprot id: Q8RCZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

273068:TTE RS12185
gene id: 273068:TTE_RS12185
uniprot id: Q8R775
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

273068:TTE RS11325
gene id: 273068:TTE_RS11325
uniprot id: Q8R7N5
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

273068:TTE RS06470
gene id: 273068:TTE_RS06470
uniprot id: Q8RA72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

273068:TTE RS10605
gene id: 273068:TTE_RS10605
uniprot id: Q8R812
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

273068:TTE RS01500
gene id: 273068:TTE_RS01500
uniprot id: Q8RCU7
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

273068:TTE RS07000
gene id: 273068:TTE_RS07000
uniprot id: Q8R9W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

273068:TTE RS00680
gene id: 273068:TTE_RS00680
uniprot id: Q8RDA5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

273068:TTE RS02865
gene id: 273068:TTE_RS02865
uniprot id: Q8RC45
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

273068:TTE RS08710
gene id: 273068:TTE_RS08710
uniprot id: Q8R916
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

273068:TTE RS06635
gene id: 273068:TTE_RS06635
uniprot id: Q8RA41
names: Similarity
messages: Belongs to the ribF family.

273068:TTE RS00090
gene id: 273068:TTE_RS00090
uniprot id: Q8RDK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

273068:TTE RS09165
gene id: 273068:TTE_RS09165
uniprot id: Q8R8T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS02570
gene id: 273068:TTE_RS02570
uniprot id: Q8RC97
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

273068:TTE RS06360
gene id: 273068:TTE_RS06360
uniprot id: Q8RA94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cytoplasm
messages: Homodimer or homotetramer.

273068:TTE RS06555
gene id: 273068:TTE_RS06555
uniprot id: Q8RA56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

273068:TTE RS10990
gene id: 273068:TTE_RS10990
uniprot id: Q8R7U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

273068:TTE RS04445
gene id: 273068:TTE_RS04445
uniprot id: Q8RB97
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

273068:TTE RS12525
gene id: 273068:TTE_RS12525
uniprot id: Q8R708
names: Similarity
messages: Belongs to the UPF0735 family.

273068:TTE RS10575
gene id: 273068:TTE_RS10575
uniprot id: Q8R816
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

273068:TTE RS12680
gene id: 273068:TTE_RS12680
uniprot id: Q8R6W6
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

273068:TTE RS01695
gene id: 273068:TTE_RS01695
uniprot id: Q8RCR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS03930
gene id: 273068:TTE_RS03930
uniprot id: Q8RBJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

273068:TTE RS04595
gene id: 273068:TTE_RS04595
uniprot id: Q8RB69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

273068:TTE RS03740
gene id: 273068:TTE_RS03740
uniprot id: Q8RBN5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

273068:TTE RS00075
gene id: 273068:TTE_RS00075
uniprot id: Q8RDK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

273068:TTE RS03020
gene id: 273068:TTE_RS03020
uniprot id: Q8RC25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

273068:TTE RS05500
gene id: 273068:TTE_RS05500
uniprot id: Q8RAQ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

273068:TTE RS00035
gene id: 273068:TTE_RS00035
uniprot id: Q8RDL1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

273068:TTE RS02110
gene id: 273068:TTE_RS02110
uniprot id: Q8RCI7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

273068:TTE RS07265
gene id: 273068:TTE_RS07265
uniprot id: Q8R6I7
names: Similarity
messages: Belongs to the UPF0236 family.

273068:TTE RS05690
gene id: 273068:TTE_RS05690
uniprot id: Q8RAL7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

273068:TTE RS03135
gene id: 273068:TTE_RS03135
uniprot id: Q8RC01
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

273068:TTE RS01280
gene id: 273068:TTE_RS01280
uniprot id: Q8RCY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

273068:TTE RS05955
gene id: 273068:TTE_RS05955
uniprot id: Q8RAH1
names: Similarity
messages: Belongs to the Fur family.

273068:TTE RS07340
gene id: 273068:TTE_RS07340
uniprot id: Q8R9R1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

273068:TTE RS00715
gene id: 273068:TTE_RS00715
uniprot id: Q8RD98
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

273068:TTE RS10995
gene id: 273068:TTE_RS10995
uniprot id: Q8R7U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

273068:TTE RS02860
gene id: 273068:TTE_RS02860
uniprot id: Q8RC46
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

273068:TTE RS06580
gene id: 273068:TTE_RS06580
uniprot id: Q8R5S4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Cell membrane
messages: Consists of an N-terminal domain, which is sufficient for the localization to the septal ring and is required for cell division, followed by a linker domain, and a C-terminal domain, which forms the translocation motor involved in chromosome segregation. The C-terminal domain can be further subdivided into alpha, beta and gamma subdomains. The alpha and beta subdomains form the DNA pump, and the gamma subdomain is a regulatory subdomain (By similarity).
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity).
messages: Homohexamer. Forms a ring that surrounds DNA (By similarity).

273068:TTE RS06750
gene id: 273068:TTE_RS06750
uniprot id: Q8RA16
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

273068:TTE RS11050
gene id: 273068:TTE_RS11050
uniprot id: Q8R7T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

273068:TTE RS06275
gene id: 273068:TTE_RS06275
uniprot id: Q8RAA8
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

273068:TTE RS01595
gene id: 273068:TTE_RS01595
uniprot id: Q8RCS9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

273068:TTE RS00145
gene id: 273068:TTE_RS00145
uniprot id: Q8R6I5
names: Function
messages: Involved in the transposition of the insertion sequence.

273068:TTE RS10820
gene id: 273068:TTE_RS10820
uniprot id: Q8R7X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

273068:TTE RS10920
gene id: 273068:TTE_RS10920
uniprot id: Q8R7V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

273068:TTE RS13240
gene id: 273068:TTE_RS13240
uniprot id: Q8R6K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

273068:TTE RS11010
gene id: 273068:TTE_RS11010
uniprot id: Q8R7U1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

273068:TTE RS07875
gene id: 273068:TTE_RS07875
uniprot id: Q8R9G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

273068:TTE RS12460
gene id: 273068:TTE_RS12460
uniprot id: Q8R721
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

273068:TTE RS01845
gene id: 273068:TTE_RS01845
uniprot id: Q8RCN6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

273068:TTE RS07125
gene id: 273068:TTE_RS07125
uniprot id: Q8R9U5
names: Function
messages: May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.

273068:TTE RS06870
gene id: 273068:TTE_RS06870
uniprot id: Q8R9Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

273068:TTE RS08025
gene id: 273068:TTE_RS08025
uniprot id: Q8R6I7
names: Similarity
messages: Belongs to the UPF0236 family.

273068:TTE RS05165
gene id: 273068:TTE_RS05165
uniprot id: Q8RAW1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

273068:TTE RS12075
gene id: 273068:TTE_RS12075
uniprot id: Q8R795
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS05640
gene id: 273068:TTE_RS05640
uniprot id: Q8RAM6
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

273068:TTE RS06975
gene id: 273068:TTE_RS06975
uniprot id: Q8R9X3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

273068:TTE RS11090
gene id: 273068:TTE_RS11090
uniprot id: Q8R7S6
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

273068:TTE RS05295
gene id: 273068:TTE_RS05295
uniprot id: Q8RAT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

273068:TTE RS12300
gene id: 273068:TTE_RS12300
uniprot id: Q8R752
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

273068:TTE RS10955
gene id: 273068:TTE_RS10955
uniprot id: Q8R7V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

273068:TTE RS12070
gene id: 273068:TTE_RS12070
uniprot id: Q8R796
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS03515
gene id: 273068:TTE_RS03515
uniprot id: Q8RBS6
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS06980
gene id: 273068:TTE_RS06980
uniprot id: Q8R9X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

273068:TTE RS00650
gene id: 273068:TTE_RS00650
uniprot id: Q8RDB1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

273068:TTE RS07260
gene id: 273068:TTE_RS07260
uniprot id: Q8R5S0
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

273068:TTE RS08950
gene id: 273068:TTE_RS08950
uniprot id: Q8R8W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

273068:TTE RS03490
gene id: 273068:TTE_RS03490
uniprot id: Q8RBT1
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS07400
gene id: 273068:TTE_RS07400
uniprot id: Q8R9Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

273068:TTE RS10945
gene id: 273068:TTE_RS10945
uniprot id: Q8R7V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

273068:TTE RS12550
gene id: 273068:TTE_RS12550
uniprot id: Q8R704
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

273068:TTE RS09455
gene id: 273068:TTE_RS09455
uniprot id: Q8R8M3
names: Similarity
messages: Belongs to the ComB family.

273068:TTE RS10290
gene id: 273068:TTE_RS10290
uniprot id: Q8R868
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS01790
gene id: 273068:TTE_RS01790
uniprot id: Q8RCP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

273068:TTE RS05650
gene id: 273068:TTE_RS05650
uniprot id: Q8RAM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

273068:TTE RS11790
gene id: 273068:TTE_RS11790
uniprot id: Q8R7E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

273068:TTE RS06970
gene id: 273068:TTE_RS06970
uniprot id: Q8R5S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

273068:TTE RS10215
gene id: 273068:TTE_RS10215
uniprot id: Q8R881
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

273068:TTE RS03800
gene id: 273068:TTE_RS03800
uniprot id: Q8RBM1
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

273068:TTE RS00910
gene id: 273068:TTE_RS00910
uniprot id: Q8RD62
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.

273068:TTE RS07205
gene id: 273068:TTE_RS07205
uniprot id: Q8R9T0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

273068:TTE RS10860
gene id: 273068:TTE_RS10860
uniprot id: Q8R7X1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

273068:TTE RS07515
gene id: 273068:TTE_RS07515
uniprot id: Q8R9N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

273068:TTE RS00115
gene id: 273068:TTE_RS00115
uniprot id: Q8RDJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

273068:TTE RS07105
gene id: 273068:TTE_RS07105
uniprot id: Q8R9U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

273068:TTE RS12315
gene id: 273068:TTE_RS12315
uniprot id: Q8R749
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

273068:TTE RS13215
gene id: 273068:TTE_RS13215
uniprot id: Q8R5P3
names: Similarity
messages: Belongs to the ParB family.

273068:TTE RS05395
gene id: 273068:TTE_RS05395
uniprot id: Q8RAS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

273068:TTE RS08145
gene id: 273068:TTE_RS08145
uniprot id: Q8R9B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

273068:TTE RS01175
gene id: 273068:TTE_RS01175
uniprot id: Q8RD10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

273068:TTE RS00545
gene id: 273068:TTE_RS00545
uniprot id: Q8R5U9
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

273068:TTE RS11215
gene id: 273068:TTE_RS11215
uniprot id: Q8R5Q0
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

273068:TTE RS05950
gene id: 273068:TTE_RS05950
uniprot id: Q8RAH2
names: Similarity
messages: Belongs to the UPF0473 family.

273068:TTE RS10080
gene id: 273068:TTE_RS10080
uniprot id: Q8R8A3
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

273068:TTE RS07950
gene id: 273068:TTE_RS07950
uniprot id: Q8R9F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity).
messages: Cytoplasm

273068:TTE RS09315
gene id: 273068:TTE_RS09315
uniprot id: Q8R8Q1
names: Function
names: Similarity
messages: Belongs to the UxaE family.
messages: Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA).

273068:TTE RS08745
gene id: 273068:TTE_RS08745
uniprot id: Q8R909
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

273068:TTE RS01755
gene id: 273068:TTE_RS01755
uniprot id: Q8RCQ3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

273068:TTE RS11455
gene id: 273068:TTE_RS11455
uniprot id: Q8R7L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

273068:TTE RS07045
gene id: 273068:TTE_RS07045
uniprot id: Q8R9V9
names: Similarity
messages: Belongs to the fabD family.

273068:TTE RS01160
gene id: 273068:TTE_RS01160
uniprot id: Q8RD13
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

273068:TTE RS03650
gene id: 273068:TTE_RS03650
uniprot id: Q8RBQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Carbohydrate importer 2 (CUT2) (TC 3.A.1.2) family.
messages: Cell membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

273068:TTE RS04720
gene id: 273068:TTE_RS04720
uniprot id: Q8RB44
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

273068:TTE RS10505
gene id: 273068:TTE_RS10505
uniprot id: Q8R828
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

273068:TTE RS11955
gene id: 273068:TTE_RS11955
uniprot id: Q8R7B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

273068:TTE RS08680
gene id: 273068:TTE_RS08680
uniprot id: Q8R922
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

273068:TTE RS00620
gene id: 273068:TTE_RS00620
uniprot id: Q8RDB7
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS12605
gene id: 273068:TTE_RS12605
uniprot id: Q8R6I5
names: Function
messages: Involved in the transposition of the insertion sequence.

273068:TTE RS05095
gene id: 273068:TTE_RS05095
uniprot id: Q8RAX6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

273068:TTE RS03860
gene id: 273068:TTE_RS03860
uniprot id: Q8RBK9
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

273068:TTE RS07255
gene id: 273068:TTE_RS07255
uniprot id: Q8R9S1
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

273068:TTE RS02730
gene id: 273068:TTE_RS02730
uniprot id: Q8RC68
names: Similarity
messages: Belongs to the peptidase S8 family.

273068:TTE RS09370
gene id: 273068:TTE_RS09370
uniprot id: Q8R8P0
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

273068:TTE RS10425
gene id: 273068:TTE_RS10425
uniprot id: Q8R842
names: Similarity
messages: Belongs to the UPF0047 family.

273068:TTE RS01620
gene id: 273068:TTE_RS01620
uniprot id: Q8RCS5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

273068:TTE RS06165
gene id: 273068:TTE_RS06165
uniprot id: Q8RAC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

273068:TTE RS02545
gene id: 273068:TTE_RS02545
uniprot id: Q8RCA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

273068:TTE RS06150
gene id: 273068:TTE_RS06150
uniprot id: Q8RAD2
names: Similarity
messages: Belongs to the asp23 family.

273068:TTE RS08275
gene id: 273068:TTE_RS08275
uniprot id: Q8R988
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

273068:TTE RS00760
gene id: 273068:TTE_RS00760
uniprot id: Q8RD92
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS08445
gene id: 273068:TTE_RS08445
uniprot id: Q8R5R4
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

273068:TTE RS05000
gene id: 273068:TTE_RS05000
uniprot id: Q8RAZ3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

273068:TTE RS07890
gene id: 273068:TTE_RS07890
uniprot id: Q8R6I2
names: Similarity
messages: Belongs to the UPF0236 family.

273068:TTE RS02905
gene id: 273068:TTE_RS02905
uniprot id: Q8R6I2
names: Similarity
messages: Belongs to the UPF0236 family.

273068:TTE RS04780
gene id: 273068:TTE_RS04780
uniprot id: Q8RB34
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

273068:TTE RS00470
gene id: 273068:TTE_RS00470
uniprot id: Q8RDE6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

273068:TTE RS11635
gene id: 273068:TTE_RS11635
uniprot id: Q8R6I2
names: Similarity
messages: Belongs to the UPF0236 family.

273068:TTE RS11020
gene id: 273068:TTE_RS11020
uniprot id: Q8R7T9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

273068:TTE RS00375
gene id: 273068:TTE_RS00375
uniprot id: Q8R5V4
names: Similarity
messages: Belongs to the class-I fumarase family.

273068:TTE RS07655
gene id: 273068:TTE_RS07655
uniprot id: Q8R9K3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

273068:TTE RS12710
gene id: 273068:TTE_RS12710
uniprot id: Q8R6W0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

273068:TTE RS01800
gene id: 273068:TTE_RS01800
uniprot id: Q8RCP4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

273068:TTE RS06270
gene id: 273068:TTE_RS06270
uniprot id: Q8RAA9
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

273068:TTE RS10435
gene id: 273068:TTE_RS10435
uniprot id: Q8R840
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

273068:TTE RS04070
gene id: 273068:TTE_RS04070
uniprot id: Q8RBG8
names: Similarity
messages: Belongs to the peptidase S49 family.

273068:TTE RS06930
gene id: 273068:TTE_RS06930
uniprot id: Q8R9Y0
names: Similarity
messages: Belongs to the DprA/Smf family.

273068:TTE RS05960
gene id: 273068:TTE_RS05960
uniprot id: Q8RAH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

273068:TTE RS09500
gene id: 273068:TTE_RS09500
uniprot id: Q8R8L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

273068:TTE RS09100
gene id: 273068:TTE_RS09100
uniprot id: Q8R8U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

273068:TTE RS07845
gene id: 273068:TTE_RS07845
uniprot id: Q8R9H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

273068:TTE RS10275
gene id: 273068:TTE_RS10275
uniprot id: Q8R871
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

273068:TTE RS08485
gene id: 273068:TTE_RS08485
uniprot id: Q8R961
names: Similarity
messages: Belongs to the acylphosphatase family.

273068:TTE RS10840
gene id: 273068:TTE_RS10840
uniprot id: Q8R7X5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

273068:TTE RS00740
gene id: 273068:TTE_RS00740
uniprot id: Q8RD94
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

273068:TTE RS00990
gene id: 273068:TTE_RS00990
uniprot id: Q8RD45
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

273068:TTE RS12305
gene id: 273068:TTE_RS12305
uniprot id: Q8R751
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

273068:TTE RS01035
gene id: 273068:TTE_RS01035
uniprot id: Q8RD35
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

273068:TTE RS05655
gene id: 273068:TTE_RS05655
uniprot id: Q8RAM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

273068:TTE RS07140
gene id: 273068:TTE_RS07140
uniprot id: Q8R9U2
names: Similarity
messages: Belongs to the asp23 family.

273068:TTE RS03275
gene id: 273068:TTE_RS03275
uniprot id: Q8RBX5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

273068:TTE RS11490
gene id: 273068:TTE_RS11490
uniprot id: Q8R7K4
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

273068:TTE RS07200
gene id: 273068:TTE_RS07200
uniprot id: Q8R9T1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

273068:TTE RS05855
gene id: 273068:TTE_RS05855
uniprot id: Q8RAI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

273068:TTE RS06565
gene id: 273068:TTE_RS06565
uniprot id: Q8RA54
names: Similarity
messages: Belongs to the CinA family.

273068:TTE RS12870
gene id: 273068:TTE_RS12870
uniprot id: Q8R6I2
names: Similarity
messages: Belongs to the UPF0236 family.

273068:TTE RS12545
gene id: 273068:TTE_RS12545
uniprot id: Q8R5P6
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

273068:TTE RS09560
gene id: 273068:TTE_RS09560
uniprot id: Q8R8K4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

273068:TTE RS00625
gene id: 273068:TTE_RS00625
uniprot id: Q8RDB6
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

273068:TTE RS06000
gene id: 273068:TTE_RS06000
uniprot id: Q8RAG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

273068:TTE RS13140
gene id: 273068:TTE_RS13140
uniprot id: Q8R6M7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

273068:TTE RS07585
gene id: 273068:TTE_RS07585
uniprot id: Q8R9L7
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

273068:TTE RS07910
gene id: 273068:TTE_RS07910
uniprot id: Q8R9F8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

273068:TTE RS06025
gene id: 273068:TTE_RS06025
uniprot id: Q8RAF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

273068:TTE RS11075
gene id: 273068:TTE_RS11075
uniprot id: Q8R7S9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

273068:TTE RS02520
gene id: 273068:TTE_RS02520
uniprot id: Q8RCA7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

273068:TTE RS12485
gene id: 273068:TTE_RS12485
uniprot id: Q8R716
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

273068:TTE RS12260
gene id: 273068:TTE_RS12260
uniprot id: Q8R760
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

273068:TTE RS06200
gene id: 273068:TTE_RS06200
uniprot id: Q8RAC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

273068:TTE RS01575
gene id: 273068:TTE_RS01575
uniprot id: Q8RCT2
names: Similarity
messages: Belongs to the Tlp family.

273068:TTE RS00300
gene id: 273068:TTE_RS00300
uniprot id: Q8RDH4
names: Activity Regulation
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Contains an N-terminal conserved nucleotide-binding domain and a C-terminal domain bound with a [4Fe-4S] cluster. The C-terminal domain forms a stable loop region and interacts with the N-terminal domain.
messages: Part of the ABC transporter Dpp involved in dipeptide transport. Responsible for energy coupling to the transport system.
messages: The C-terminal iron-sulfur cluster may stabilize the structure of the C-terminal loops and may function in the regulation of the transport process.

273068:TTE RS04230
gene id: 273068:TTE_RS04230
uniprot id: Q8RBE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

273068:TTE RS07300
gene id: 273068:TTE_RS07300
uniprot id: P58858
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

273068:TTE RS12715
gene id: 273068:TTE_RS12715
uniprot id: Q8R5P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

273068:TTE RS11930
gene id: 273068:TTE_RS11930
uniprot id: Q8R7C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

273068:TTE RS08610
gene id: 273068:TTE_RS08610
uniprot id: Q8R936
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane

273068:TTE RS04410
gene id: 273068:TTE_RS04410
uniprot id: Q8RBA4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

273068:TTE RS05450
gene id: 273068:TTE_RS05450
uniprot id: Q8R6H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

273068:TTE RS10800
gene id: 273068:TTE_RS10800
uniprot id: Q8R7Y3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

273068:TTE RS08790
gene id: 273068:TTE_RS08790
uniprot id: Q8R901
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

273068:TTE RS10255
gene id: 273068:TTE_RS10255
uniprot id: Q8R5Q3
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273068:TTE RS03090
gene id: 273068:TTE_RS03090
uniprot id: Q8RC12
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273068:TTE RS03935
gene id: 273068:TTE_RS03935
uniprot id: Q8RBJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

273068:TTE RS09180
gene id: 273068:TTE_RS09180
uniprot id: Q8R8S8
names: Similarity
messages: Belongs to the transpeptidase family.

273068:TTE RS00935
gene id: 273068:TTE_RS00935
uniprot id: Q8RD57
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

273068:TTE RS12215
gene id: 273068:TTE_RS12215
uniprot id: Q8R769
names: Similarity
messages: Belongs to the GerABKA family.

273068:TTE RS04170
gene id: 273068:TTE_RS04170
uniprot id: Q8RBE9
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS09475
gene id: 273068:TTE_RS09475
uniprot id: Q8R8L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

273068:TTE RS01290
gene id: 273068:TTE_RS01290
uniprot id: Q8RCY7
names: Similarity
messages: Belongs to the threonine aldolase family.

273068:TTE RS08255
gene id: 273068:TTE_RS08255
uniprot id: Q8R993
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

273068:TTE RS13195
gene id: 273068:TTE_RS13195
uniprot id: Q8R6L6
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

273068:TTE RS10930
gene id: 273068:TTE_RS10930
uniprot id: Q8R7V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

273068:TTE RS02210
gene id: 273068:TTE_RS02210
uniprot id: Q8RCG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

273068:TTE RS00315
gene id: 273068:TTE_RS00315
uniprot id: Q8RDH0
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

273068:TTE RS06085
gene id: 273068:TTE_RS06085
uniprot id: Q8RAE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

273068:TTE RS06190
gene id: 273068:TTE_RS06190
uniprot id: Q8RAC4
names: Similarity
messages: Belongs to the TlyA family.

273068:TTE RS07885
gene id: 273068:TTE_RS07885
uniprot id: Q8R9G2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm

273068:TTE RS00795
gene id: 273068:TTE_RS00795
uniprot id: Q8RD85
names: Cofactor
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.

273068:TTE RS10270
gene id: 273068:TTE_RS10270
uniprot id: Q8R872
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

273068:TTE RS06495
gene id: 273068:TTE_RS06495
uniprot id: Q8RA68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

273068:TTE RS02135
gene id: 273068:TTE_RS02135
uniprot id: Q8RCI2
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS02410
gene id: 273068:TTE_RS02410
uniprot id: Q8RCC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

273068:TTE RS01445
gene id: 273068:TTE_RS01445
uniprot id: Q8RCV7
names: Similarity
messages: Belongs to the UPF0236 family.

273068:TTE RS06955
gene id: 273068:TTE_RS06955
uniprot id: Q8R9X6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

273068:TTE RS02690
gene id: 273068:TTE_RS02690
uniprot id: Q8RC74
names: Similarity
messages: Belongs to the asp23 family.

273068:TTE RS02920
gene id: 273068:TTE_RS02920
uniprot id: Q8RC35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS01650
gene id: 273068:TTE_RS01650
uniprot id: Q8RCR9
names: Similarity
messages: Belongs to the CapA family.

273068:TTE RS00380
gene id: 273068:TTE_RS00380
uniprot id: Q8R5V3
names: Similarity
messages: Belongs to the class-I fumarase family.

273068:TTE RS09480
gene id: 273068:TTE_RS09480
uniprot id: Q8R8L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

273068:TTE RS08575
gene id: 273068:TTE_RS08575
uniprot id: Q8R5R3
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

273068:TTE RS04960
gene id: 273068:TTE_RS04960
uniprot id: Q8RB01
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

273068:TTE RS11895
gene id: 273068:TTE_RS11895
uniprot id: Q8R7C9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

273068:TTE RS09835
gene id: 273068:TTE_RS09835
uniprot id: Q8R8F1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273068:TTE RS10965
gene id: 273068:TTE_RS10965
uniprot id: Q8R7V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

273068:TTE RS06070
gene id: 273068:TTE_RS06070
uniprot id: Q8RAE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

273068:TTE RS07650
gene id: 273068:TTE_RS07650
uniprot id: Q8R9K4
names: Similarity
messages: Belongs to the RutC family.

273068:TTE RS00290
gene id: 273068:TTE_RS00290
uniprot id: Q8RDH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS07810
gene id: 273068:TTE_RS07810
uniprot id: Q8R9H6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

273068:TTE RS08570
gene id: 273068:TTE_RS08570
uniprot id: Q8R943
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

273068:TTE RS07425
gene id: 273068:TTE_RS07425
uniprot id: Q8R9P5
names: Similarity
messages: Belongs to the serpin family.

273068:TTE RS09655
gene id: 273068:TTE_RS09655
uniprot id: Q8R8I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

273068:TTE RS12235
gene id: 273068:TTE_RS12235
uniprot id: Q8R765
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

273068:TTE RS12520
gene id: 273068:TTE_RS12520
uniprot id: Q8R709
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

273068:TTE RS07530
gene id: 273068:TTE_RS07530
uniprot id: Q8R9M7
names: Similarity
messages: Belongs to the TrpC family.

273068:TTE RS12580
gene id: 273068:TTE_RS12580
uniprot id: Q8R6Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

273068:TTE RS06005
gene id: 273068:TTE_RS06005
uniprot id: Q8RAG1
names: Similarity
messages: Belongs to the GSP E family.

273068:TTE RS03210
gene id: 273068:TTE_RS03210
uniprot id: Q8RBY6
names: Similarity
messages: Belongs to the polysaccharide synthase family.

273068:TTE RS07335
gene id: 273068:TTE_RS07335
uniprot id: Q8R9R2
names: Similarity
messages: Belongs to the HypE family.

273068:TTE RS12780
gene id: 273068:TTE_RS12780
uniprot id: Q8R6U5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

273068:TTE RS04345
gene id: 273068:TTE_RS04345
uniprot id: Q8RBB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

273068:TTE RS09505
gene id: 273068:TTE_RS09505
uniprot id: Q8R8L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

273068:TTE RS01690
gene id: 273068:TTE_RS01690
uniprot id: Q8RCR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS05070
gene id: 273068:TTE_RS05070
uniprot id: Q8R6I2
names: Similarity
messages: Belongs to the UPF0236 family.

273068:TTE RS12205
gene id: 273068:TTE_RS12205
uniprot id: Q8R771
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

273068:TTE RS06320
gene id: 273068:TTE_RS06320
uniprot id: Q8RAA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

273068:TTE RS06575
gene id: 273068:TTE_RS06575
uniprot id: Q8RA52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

273068:TTE RS08920
gene id: 273068:TTE_RS08920
uniprot id: Q8R8X4
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS12490
gene id: 273068:TTE_RS12490
uniprot id: Q8R715
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

273068:TTE RS06055
gene id: 273068:TTE_RS06055
uniprot id: Q8RAF1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

273068:TTE RS10865
gene id: 273068:TTE_RS10865
uniprot id: Q8R7X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

273068:TTE RS06785
gene id: 273068:TTE_RS06785
uniprot id: Q8RA09
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

273068:TTE RS10430
gene id: 273068:TTE_RS10430
uniprot id: Q8R841
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

273068:TTE RS03880
gene id: 273068:TTE_RS03880
uniprot id: Q8RBK4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

273068:TTE RS03835
gene id: 273068:TTE_RS03835
uniprot id: Q8RBL4
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

273068:TTE RS07720
gene id: 273068:TTE_RS07720
uniprot id: Q8R9J4
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

273068:TTE RS07870
gene id: 273068:TTE_RS07870
uniprot id: Q8R9G5
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS10385
gene id: 273068:TTE_RS10385
uniprot id: Q8R851
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

273068:TTE RS03045
gene id: 273068:TTE_RS03045
uniprot id: Q8RC20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

273068:TTE RS12275
gene id: 273068:TTE_RS12275
uniprot id: Q8R757
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

273068:TTE RS09900
gene id: 273068:TTE_RS09900
uniprot id: Q8R8D8
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS07240
gene id: 273068:TTE_RS07240
uniprot id: Q8R9S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

273068:TTE RS10420
gene id: 273068:TTE_RS10420
uniprot id: Q8R844
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

273068:TTE RS00565
gene id: 273068:TTE_RS00565
uniprot id: Q8RDC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

273068:TTE RS07900
gene id: 273068:TTE_RS07900
uniprot id: Q8R9G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

273068:TTE RS09420
gene id: 273068:TTE_RS09420
uniprot id: Q8R8N0
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

273068:TTE RS08080
gene id: 273068:TTE_RS08080
uniprot id: Q8R9C7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

273068:TTE RS02590
gene id: 273068:TTE_RS02590
uniprot id: Q8RC93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

273068:TTE RS01805
gene id: 273068:TTE_RS01805
uniprot id: Q8RCP3
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

273068:TTE RS02125
gene id: 273068:TTE_RS02125
uniprot id: Q8RCI4
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS07730
gene id: 273068:TTE_RS07730
uniprot id: Q8R9J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

273068:TTE RS07795
gene id: 273068:TTE_RS07795
uniprot id: Q8R9H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

273068:TTE RS07905
gene id: 273068:TTE_RS07905
uniprot id: Q8R9F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

273068:TTE RS06710
gene id: 273068:TTE_RS06710
uniprot id: Q8RA26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

273068:TTE RS00015
gene id: 273068:TTE_RS00015
uniprot id: Q8RDL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

273068:TTE RS08815
gene id: 273068:TTE_RS08815
uniprot id: Q8R8Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

273068:TTE RS06410
gene id: 273068:TTE_RS06410
uniprot id: Q8RA84
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

273068:TTE RS06925
gene id: 273068:TTE_RS06925
uniprot id: Q8R9Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

273068:TTE RS06525
gene id: 273068:TTE_RS06525
uniprot id: Q8RA62
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

273068:TTE RS00140
gene id: 273068:TTE_RS00140
uniprot id: Q8RDJ4
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

273068:TTE RS06335
gene id: 273068:TTE_RS06335
uniprot id: Q8RA97
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

273068:TTE RS00500
gene id: 273068:TTE_RS00500
uniprot id: Q8RDE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

273068:TTE RS02610
gene id: 273068:TTE_RS02610
uniprot id: Q8RC89
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

273068:TTE RS11915
gene id: 273068:TTE_RS11915
uniprot id: Q8R6I5
names: Function
messages: Involved in the transposition of the insertion sequence.

273068:TTE RS13325
gene id: 273068:TTE_RS13325
uniprot id: Q8R8E5
names: Similarity
messages: Belongs to the peptidase A24 family.

273068:TTE RS10855
gene id: 273068:TTE_RS10855
uniprot id: Q8R7X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

273068:TTE RS08410
gene id: 273068:TTE_RS08410
uniprot id: Q8R973
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

273068:TTE RS01625
gene id: 273068:TTE_RS01625
uniprot id: Q8RCS4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

273068:TTE RS09240
gene id: 273068:TTE_RS09240
uniprot id: Q8R8R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

273068:TTE RS07180
gene id: 273068:TTE_RS07180
uniprot id: Q8R9T4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

273068:TTE RS06260
gene id: 273068:TTE_RS06260
uniprot id: Q8RAB1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Although strongly related to the XerC and XerD proteins, it lacks the Tyr active site, as well as the Arg-His-Arg-His (R-H-R-H) sandwich residues that are clustered with it. It however contains the Thr-Arg-Gln tripeptide, which is characteristic of the XerD subfamily.
messages: Belongs to the 'phage' integrase family.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

273068:TTE RS10985
gene id: 273068:TTE_RS10985
uniprot id: Q8R7U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

273068:TTE RS08940
gene id: 273068:TTE_RS08940
uniprot id: Q8R8X0
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

273068:TTE RS07445
gene id: 273068:TTE_RS07445
uniprot id: Q8R9P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

273068:TTE RS04725
gene id: 273068:TTE_RS04725
uniprot id: Q8RB43
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

273068:TTE RS01300
gene id: 273068:TTE_RS01300
uniprot id: Q8RCY6
names: Similarity
messages: Belongs to the UPF0597 family.

273068:TTE RS12330
gene id: 273068:TTE_RS12330
uniprot id: Q8R745
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

273068:TTE RS05260
gene id: 273068:TTE_RS05260
uniprot id: Q8RAU4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

273068:TTE RS07675
gene id: 273068:TTE_RS07675
uniprot id: Q8R9J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

273068:TTE RS07410
gene id: 273068:TTE_RS07410
uniprot id: Q8R9P8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

273068:TTE RS01190
gene id: 273068:TTE_RS01190
uniprot id: Q8RD06
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS10195
gene id: 273068:TTE_RS10195
uniprot id: Q8R883
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

273068:TTE RS03600
gene id: 273068:TTE_RS03600
uniprot id: Q8RBR1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the HepT RNase toxin family.
messages: Homodimer, probably forms a complex with cognate antitoxin TTE0751.
messages: Modified by cognate antitoxin TTE0751; probably at least 2 successive AMPylation events occur on Tyr-81.
messages: Probable toxic component of a putative type VII toxin-antitoxin (TA) system, probably an RNase. Probably neutralized by cognate antitoxin TTE0751. Neutralization may be due to AMPylation by TTE0751.

273068:TTE RS09695
gene id: 273068:TTE_RS09695
uniprot id: Q8R8H9
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

273068:TTE RS06910
gene id: 273068:TTE_RS06910
uniprot id: Q8R9Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

273068:TTE RS03080
gene id: 273068:TTE_RS03080
uniprot id: Q8RC14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

273068:TTE RS00850
gene id: 273068:TTE_RS00850
uniprot id: Q8RD74
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

273068:TTE RS03985
gene id: 273068:TTE_RS03985
uniprot id: Q8RBI4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273068:TTE RS01540
gene id: 273068:TTE_RS01540
uniprot id: Q8RCT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

273068:TTE RS00900
gene id: 273068:TTE_RS00900
uniprot id: Q8RD64
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS10925
gene id: 273068:TTE_RS10925
uniprot id: Q8R7V8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

273068:TTE RS02830
gene id: 273068:TTE_RS02830
uniprot id: Q8RC52
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

273068:TTE RS08330
gene id: 273068:TTE_RS08330
uniprot id: Q8R986
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

273068:TTE RS00665
gene id: 273068:TTE_RS00665
uniprot id: Q8RDA8
names: Similarity
messages: Belongs to the HypD family.

273068:TTE RS07605
gene id: 273068:TTE_RS07605
uniprot id: Q8R9L3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

273068:TTE RS07555
gene id: 273068:TTE_RS07555
uniprot id: Q8R9M3
names: Similarity
messages: Belongs to the UPF0045 family.

273068:TTE RS06945
gene id: 273068:TTE_RS06945
uniprot id: Q8R9X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

273068:TTE RS06805
gene id: 273068:TTE_RS06805
uniprot id: Q8RA05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

273068:TTE RS05485
gene id: 273068:TTE_RS05485
uniprot id: Q8R6I5
names: Function
messages: Involved in the transposition of the insertion sequence.

273068:TTE RS02255
gene id: 273068:TTE_RS02255
uniprot id: Q8RCF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

273068:TTE RS07345
gene id: 273068:TTE_RS07345
uniprot id: Q8R9R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

273068:TTE RS10205
gene id: 273068:TTE_RS10205
uniprot id: Q8R5Q4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

273068:TTE RS08800
gene id: 273068:TTE_RS08800
uniprot id: Q8R8Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

273068:TTE RS12470
gene id: 273068:TTE_RS12470
uniprot id: Q8R719
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

273068:TTE RS13260
gene id: 273068:TTE_RS13260
uniprot id: Q8R6K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

273068:TTE RS01580
gene id: 273068:TTE_RS01580
uniprot id: Q8RCT1
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS07865
gene id: 273068:TTE_RS07865
uniprot id: Q8R9G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

273068:TTE RS05405
gene id: 273068:TTE_RS05405
uniprot id: Q8RAR8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

273068:TTE RS11130
gene id: 273068:TTE_RS11130
uniprot id: Q8R7R8
names: Similarity
messages: Belongs to the CtsR family.

273068:TTE RS02160
gene id: 273068:TTE_RS02160
uniprot id: Q8RCH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

273068:TTE RS08550
gene id: 273068:TTE_RS08550
uniprot id: Q8R947
names: Cofactor
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

273068:TTE RS07735
gene id: 273068:TTE_RS07735
uniprot id: Q8R9J1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

273068:TTE RS07305
gene id: 273068:TTE_RS07305
uniprot id: Q8R9R7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

273068:TTE RS13170
gene id: 273068:TTE_RS13170
uniprot id: Q8R6M1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

273068:TTE RS12570
gene id: 273068:TTE_RS12570
uniprot id: Q8R700
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273068:TTE RS07165
gene id: 273068:TTE_RS07165
uniprot id: Q8R9T7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

273068:TTE RS02890
gene id: 273068:TTE_RS02890
uniprot id: Q8RC40
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

273068:TTE RS05935
gene id: 273068:TTE_RS05935
uniprot id: Q8RAH4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

273068:TTE RS03370
gene id: 273068:TTE_RS03370
uniprot id: Q8RBV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

273068:TTE RS00110
gene id: 273068:TTE_RS00110
uniprot id: Q8RDJ8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

273068:TTE RS02840
gene id: 273068:TTE_RS02840
uniprot id: Q8RC50
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS04495
gene id: 273068:TTE_RS04495
uniprot id: Q8RB89
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

273068:TTE RS07325
gene id: 273068:TTE_RS07325
uniprot id: Q8R9R5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

273068:TTE RS11015
gene id: 273068:TTE_RS11015
uniprot id: Q8R7U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

273068:TTE RS11880
gene id: 273068:TTE_RS11880
uniprot id: Q8R7D2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

273068:TTE RS00845
gene id: 273068:TTE_RS00845
uniprot id: Q8RD75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273068:TTE RS12955
gene id: 273068:TTE_RS12955
uniprot id: Q8R6R3
names: Similarity
messages: Belongs to the peptidase U62 family.

273068:TTE RS04220
gene id: 273068:TTE_RS04220
uniprot id: Q8RBE1
names: Similarity
messages: Belongs to the peptidase C40 family.

273068:TTE RS08795
gene id: 273068:TTE_RS08795
uniprot id: Q8R900
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

273068:TTE RS08450
gene id: 273068:TTE_RS08450
uniprot id: Q8R968
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

273068:TTE RS02375
gene id: 273068:TTE_RS02375
uniprot id: Q8RCD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

273068:TTE RS08670
gene id: 273068:TTE_RS08670
uniprot id: Q8R924
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

273068:TTE RS03850
gene id: 273068:TTE_RS03850
uniprot id: Q8RBL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS09245
gene id: 273068:TTE_RS09245
uniprot id: Q8R8R5
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

273068:TTE RS12630
gene id: 273068:TTE_RS12630
uniprot id: Q8R6X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

273068:TTE RS01020
gene id: 273068:TTE_RS01020
uniprot id: Q8RD38
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

273068:TTE RS05740
gene id: 273068:TTE_RS05740
uniprot id: Q8RAK7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

273068:TTE RS06480
gene id: 273068:TTE_RS06480
uniprot id: Q8RA70
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

273068:TTE RS07320
gene id: 273068:TTE_RS07320
uniprot id: Q8R9R6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

273068:TTE RS00095
gene id: 273068:TTE_RS00095
uniprot id: Q8RDK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

273068:TTE RS10280
gene id: 273068:TTE_RS10280
uniprot id: Q8R870
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

273068:TTE RS02695
gene id: 273068:TTE_RS02695
uniprot id: Q8RC73
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

273068:TTE RS05970
gene id: 273068:TTE_RS05970
uniprot id: Q8RAG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

273068:TTE RS07840
gene id: 273068:TTE_RS07840
uniprot id: Q8R9H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

273068:TTE RS09210
gene id: 273068:TTE_RS09210
uniprot id: Q8R8S2
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS07825
gene id: 273068:TTE_RS07825
uniprot id: Q8R9H3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

273068:TTE RS07780
gene id: 273068:TTE_RS07780
uniprot id: Q8R9I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

273068:TTE RS07120
gene id: 273068:TTE_RS07120
uniprot id: Q8R9U6
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

273068:TTE RS09215
gene id: 273068:TTE_RS09215
uniprot id: Q8R8S1
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS07060
gene id: 273068:TTE_RS07060
uniprot id: Q8R9V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

273068:TTE RS01395
gene id: 273068:TTE_RS01395
uniprot id: Q8RCW7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

273068:TTE RS04015
gene id: 273068:TTE_RS04015
uniprot id: Q8RBH9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

273068:TTE RS08160
gene id: 273068:TTE_RS08160
uniprot id: Q8R9B1
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS09305
gene id: 273068:TTE_RS09305
uniprot id: Q8R8Q3
names: Similarity
messages: Belongs to the FGGY kinase family.

273068:TTE RS09610
gene id: 273068:TTE_RS09610
uniprot id: Q8R8J4
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

273068:TTE RS12500
gene id: 273068:TTE_RS12500
uniprot id: Q8R713
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

273068:TTE RS10210
gene id: 273068:TTE_RS10210
uniprot id: Q8R882
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

273068:TTE RS08750
gene id: 273068:TTE_RS08750
uniprot id: Q8R6I7
names: Similarity
messages: Belongs to the UPF0236 family.

273068:TTE RS02595
gene id: 273068:TTE_RS02595
uniprot id: Q8RC92
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

273068:TTE RS06185
gene id: 273068:TTE_RS06185
uniprot id: Q8RAC5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

273068:TTE RS03175
gene id: 273068:TTE_RS03175
uniprot id: Q8RBZ3
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

273068:TTE RS10960
gene id: 273068:TTE_RS10960
uniprot id: Q8R7V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

273068:TTE RS11350
gene id: 273068:TTE_RS11350
uniprot id: Q8R7N0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

273068:TTE RS06875
gene id: 273068:TTE_RS06875
uniprot id: Q8R9Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm
messages: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum.

273068:TTE RS09290
gene id: 273068:TTE_RS09290
uniprot id: Q8R8Q6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

273068:TTE RS01415
gene id: 273068:TTE_RS01415
uniprot id: Q8RCW3
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS01505
gene id: 273068:TTE_RS01505
uniprot id: Q8RCU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

273068:TTE RS09435
gene id: 273068:TTE_RS09435
uniprot id: Q8R8M7
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS04190
gene id: 273068:TTE_RS04190
uniprot id: Q8RBE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

273068:TTE RS10850
gene id: 273068:TTE_RS10850
uniprot id: Q8R7X3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

273068:TTE RS05595
gene id: 273068:TTE_RS05595
uniprot id: Q8R6H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

273068:TTE RS10890
gene id: 273068:TTE_RS10890
uniprot id: Q8R7W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

273068:TTE RS03905
gene id: 273068:TTE_RS03905
uniprot id: Q8RBJ9
names: Similarity
messages: Belongs to the asparagine synthetase family.

273068:TTE RS08455
gene id: 273068:TTE_RS08455
uniprot id: Q8R967
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

273068:TTE RS05200
gene id: 273068:TTE_RS05200
uniprot id: Q8RAV6
names: Similarity
messages: Belongs to the peptidase S58 family.

273068:TTE RS06705
gene id: 273068:TTE_RS06705
uniprot id: Q8RA27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

273068:TTE RS05745
gene id: 273068:TTE_RS05745
uniprot id: Q8RAK6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

273068:TTE RS12510
gene id: 273068:TTE_RS12510
uniprot id: Q8R711
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

273068:TTE RS12415
gene id: 273068:TTE_RS12415
uniprot id: Q8R727
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

273068:TTE RS00440
gene id: 273068:TTE_RS00440
uniprot id: Q8RDF1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

273068:TTE RS01380
gene id: 273068:TTE_RS01380
uniprot id: Q8RCX0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273068:TTE RS08975
gene id: 273068:TTE_RS08975
uniprot id: Q8R8W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

273068:TTE RS00125
gene id: 273068:TTE_RS00125
uniprot id: Q8RDJ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

273068:TTE RS07860
gene id: 273068:TTE_RS07860
uniprot id: Q8R9G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

273068:TTE RS06350
gene id: 273068:TTE_RS06350
uniprot id: Q8R5S6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

273068:TTE RS11140
gene id: 273068:TTE_RS11140
uniprot id: Q8R7R6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

273068:TTE RS12535
gene id: 273068:TTE_RS12535
uniprot id: Q8R706
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS02330
gene id: 273068:TTE_RS02330
uniprot id: Q8RCE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

273068:TTE RS10830
gene id: 273068:TTE_RS10830
uniprot id: Q8R7X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

273068:TTE RS03110
gene id: 273068:TTE_RS03110
uniprot id: Q8RC08
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS04680
gene id: 273068:TTE_RS04680
uniprot id: Q8RB52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

273068:TTE RS03450
gene id: 273068:TTE_RS03450
uniprot id: Q8RBT9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

273068:TTE RS09225
gene id: 273068:TTE_RS09225
uniprot id: Q8R8R9
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

273068:TTE RS06830
gene id: 273068:TTE_RS06830
uniprot id: Q8RA00
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

273068:TTE RS11195
gene id: 273068:TTE_RS11195
uniprot id: Q8R7Q4
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS06625
gene id: 273068:TTE_RS06625
uniprot id: Q8RA43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

273068:TTE RS03030
gene id: 273068:TTE_RS03030
uniprot id: Q8RC23
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

273068:TTE RS04115
gene id: 273068:TTE_RS04115
uniprot id: Q8RBG0
names: Similarity
messages: Belongs to the UPF0340 family.

273068:TTE RS06445
gene id: 273068:TTE_RS06445
uniprot id: Q8RA77
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

273068:TTE RS04600
gene id: 273068:TTE_RS04600
uniprot id: Q8RB68
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

273068:TTE RS12635
gene id: 273068:TTE_RS12635
uniprot id: Q8R6X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

273068:TTE RS02880
gene id: 273068:TTE_RS02880
uniprot id: Q8RC42
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

273068:TTE RS08855
gene id: 273068:TTE_RS08855
uniprot id: Q8R8Y7
names: Similarity
messages: Belongs to the UPF0251 family.

273068:TTE RS03260
gene id: 273068:TTE_RS03260
uniprot id: Q8RBX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

273068:TTE RS10560
gene id: 273068:TTE_RS10560
uniprot id: Q8R819
names: Function
messages: Involved in the transposition of the insertion sequence.

273068:TTE RS00430
gene id: 273068:TTE_RS00430
uniprot id: Q8RDF3
names: Similarity
messages: Belongs to the DsrF/TusC family.

273068:TTE RS07160
gene id: 273068:TTE_RS07160
uniprot id: Q8R9T8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

273068:TTE RS01570
gene id: 273068:TTE_RS01570
uniprot id: Q8RCT3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

273068:TTE RS01910
gene id: 273068:TTE_RS01910
uniprot id: Q8RCM5
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS05625
gene id: 273068:TTE_RS05625
uniprot id: Q8RAM9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

273068:TTE RS00925
gene id: 273068:TTE_RS00925
uniprot id: Q8RD59
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

273068:TTE RS06520
gene id: 273068:TTE_RS06520
uniprot id: Q8RA63
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

273068:TTE RS03465
gene id: 273068:TTE_RS03465
uniprot id: Q8RBT6
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

273068:TTE RS00700
gene id: 273068:TTE_RS00700
uniprot id: Q8RDA1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

273068:TTE RS09660
gene id: 273068:TTE_RS09660
uniprot id: Q8R8I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

273068:TTE RS00685
gene id: 273068:TTE_RS00685
uniprot id: Q8RDA4
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

273068:TTE RS07835
gene id: 273068:TTE_RS07835
uniprot id: Q8R9H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

273068:TTE RS02350
gene id: 273068:TTE_RS02350
uniprot id: Q8RCE0
names: Similarity
messages: Belongs to the FlgM family.

273068:TTE RS06570
gene id: 273068:TTE_RS06570
uniprot id: Q8RA53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

273068:TTE RS12290
gene id: 273068:TTE_RS12290
uniprot id: Q8R754
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

273068:TTE RS01860
gene id: 273068:TTE_RS01860
uniprot id: Q8RCN3
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

273068:TTE RS06965
gene id: 273068:TTE_RS06965
uniprot id: Q8R9X4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

273068:TTE RS00040
gene id: 273068:TTE_RS00040
uniprot id: Q8RDL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

273068:TTE RS00955
gene id: 273068:TTE_RS00955
uniprot id: Q8RD53
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS00100
gene id: 273068:TTE_RS00100
uniprot id: Q8RDK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

273068:TTE RS08715
gene id: 273068:TTE_RS08715
uniprot id: Q8R915
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

273068:TTE RS04010
gene id: 273068:TTE_RS04010
uniprot id: Q8R6I7
names: Similarity
messages: Belongs to the UPF0236 family.

273068:TTE RS11150
gene id: 273068:TTE_RS11150
uniprot id: Q8R7R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

273068:TTE RS05345
gene id: 273068:TTE_RS05345
uniprot id: Q8RAS9
names: Similarity
messages: Belongs to the histone deacetylase family.

273068:TTE RS04815
gene id: 273068:TTE_RS04815
uniprot id: Q8RB27
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspI family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

273068:TTE RS04925
gene id: 273068:TTE_RS04925
uniprot id: Q8RB06
names: Similarity
messages: Belongs to the creatininase superfamily.

273068:TTE RS05515
gene id: 273068:TTE_RS05515
uniprot id: Q8RAQ1
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

273068:TTE RS05940
gene id: 273068:TTE_RS05940
uniprot id: Q8RAH3
names: Similarity
messages: Belongs to the UPF0297 family.

273068:TTE RS00690
gene id: 273068:TTE_RS00690
uniprot id: Q8RDA3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273068:TTE RS10825
gene id: 273068:TTE_RS10825
uniprot id: Q8R7X8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

273068:TTE RS06100
gene id: 273068:TTE_RS06100
uniprot id: Q8RAE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

273068:TTE RS12860
gene id: 273068:TTE_RS12860
uniprot id: Q8R6T0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

273068:TTE RS13265
gene id: 273068:TTE_RS13265
uniprot id: Q8R6K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

273068:TTE RS13125
gene id: 273068:TTE_RS13125
uniprot id: Q8R6M9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

273068:TTE RS11120
gene id: 273068:TTE_RS11120
uniprot id: Q8R7S0
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

273068:TTE RS04310
gene id: 273068:TTE_RS04310
uniprot id: Q8RBC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

273068:TTE RS01025
gene id: 273068:TTE_RS01025
uniprot id: Q8RD37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

273068:TTE RS03510
gene id: 273068:TTE_RS03510
uniprot id: Q8RBS7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

273068:TTE RS07560
gene id: 273068:TTE_RS07560
uniprot id: Q8R9M2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

273068:TTE RS11375
gene id: 273068:TTE_RS11375
uniprot id: Q8R7M5
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

273068:TTE RS11265
gene id: 273068:TTE_RS11265
uniprot id: Q8R7P4
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

273068:TTE RS09190
gene id: 273068:TTE_RS09190
uniprot id: Q8R8S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

273068:TTE RS12465
gene id: 273068:TTE_RS12465
uniprot id: Q8R720
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

273068:TTE RS03655
gene id: 273068:TTE_RS03655
uniprot id: Q8RBQ0
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS08805
gene id: 273068:TTE_RS08805
uniprot id: Q8R8Z8
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

273068:TTE RS11175
gene id: 273068:TTE_RS11175
uniprot id: Q8R7Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

273068:TTE RS00220
gene id: 273068:TTE_RS00220
uniprot id: Q8RDI4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

273068:TTE RS06155
gene id: 273068:TTE_RS06155
uniprot id: Q8RAD1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

273068:TTE RS02620
gene id: 273068:TTE_RS02620
uniprot id: Q8RC88
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

273068:TTE RS03035
gene id: 273068:TTE_RS03035
uniprot id: Q8RC22
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

273068:TTE RS11870
gene id: 273068:TTE_RS11870
uniprot id: Q8R7D4
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS09325
gene id: 273068:TTE_RS09325
uniprot id: Q8R8P9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

273068:TTE RS11795
gene id: 273068:TTE_RS11795
uniprot id: Q8R7E8
names: Function
names: Subcellular Location Annotation
messages: Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA).
messages: Cytoplasm

273068:TTE RS12740
gene id: 273068:TTE_RS12740
uniprot id: Q8R6V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

273068:TTE RS06680
gene id: 273068:TTE_RS06680
uniprot id: Q8RA32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

273068:TTE RS07850
gene id: 273068:TTE_RS07850
uniprot id: Q8R9G9
names: Similarity
messages: Belongs to the UPF0749 family.

273068:TTE RS09400
gene id: 273068:TTE_RS09400
uniprot id: Q8R8N4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

273068:TTE RS02115
gene id: 273068:TTE_RS02115
uniprot id: Q8RCI6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

273068:TTE RS03915
gene id: 273068:TTE_RS03915
uniprot id: Q8RBJ7
names: Similarity
messages: Belongs to the glutamate synthase family.

273068:TTE RS00645
gene id: 273068:TTE_RS00645
uniprot id: Q8RDB2
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

273068:TTE RS11485
gene id: 273068:TTE_RS11485
uniprot id: Q8R7K5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

273068:TTE RS12755
gene id: 273068:TTE_RS12755
uniprot id: Q8R6V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

273068:TTE RS00295
gene id: 273068:TTE_RS00295
uniprot id: Q8RDH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

273068:TTE RS12120
gene id: 273068:TTE_RS12120
uniprot id: Q8R786
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

273068:TTE RS08480
gene id: 273068:TTE_RS08480
uniprot id: Q8R962
names: Similarity
messages: Belongs to the sigma-54 factor family.

273068:TTE RS04710
gene id: 273068:TTE_RS04710
uniprot id: Q8RB46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

273068:TTE RS03050
gene id: 273068:TTE_RS03050
uniprot id: Q8R5T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

273068:TTE RS12210
gene id: 273068:TTE_RS12210
uniprot id: Q8R770
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

273068:TTE RS06010
gene id: 273068:TTE_RS06010
uniprot id: Q8RAG0
names: Similarity
messages: Belongs to the GSP E family.

273068:TTE RS10455
gene id: 273068:TTE_RS10455
uniprot id: Q8R836
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

273068:TTE RS02190
gene id: 273068:TTE_RS02190
uniprot id: Q8RCH0
names: Subcellular Location Annotation
messages: Membrane

273068:TTE RS00445
gene id: 273068:TTE_RS00445
uniprot id: Q8RDF0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

273068:TTE RS09665
gene id: 273068:TTE_RS09665
uniprot id: Q8R8I4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

273068:TTE RS06745
gene id: 273068:TTE_RS06745
uniprot id: Q8RA17
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

273068:TTE RS02540
gene id: 273068:TTE_RS02540
uniprot id: Q8RCA3
names: Similarity
messages: Belongs to the carbamate kinase family.

273068:TTE RS10950
gene id: 273068:TTE_RS10950
uniprot id: Q8R7V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

273068:TTE RS01320
gene id: 273068:TTE_RS01320
uniprot id: Q8RCY2
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

273068:TTE RS11055
gene id: 273068:TTE_RS11055
uniprot id: Q8R7T3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

273068:TTE RS06600
gene id: 273068:TTE_RS06600
uniprot id: Q8RA48
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

273068:TTE RS03565
gene id: 273068:TTE_RS03565
uniprot id: Q8R6I7
names: Similarity
messages: Belongs to the UPF0236 family.

273068:TTE RS08195
gene id: 273068:TTE_RS08195
uniprot id: Q8R9A5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

273068:TTE RS03585
gene id: 273068:TTE_RS03585
uniprot id: Q8RBR4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

273068:TTE RS08120
gene id: 273068:TTE_RS08120
uniprot id: Q8R9B9
names: Similarity
messages: Belongs to the peptidase A31 family.

273068:TTE RS12265
gene id: 273068:TTE_RS12265
uniprot id: Q8R759
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

273068:TTE RS10355
gene id: 273068:TTE_RS10355
uniprot id: Q8R857
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

273068:TTE RS10315
gene id: 273068:TTE_RS10315
uniprot id: Q8R864
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

273068:TTE RS10495
gene id: 273068:TTE_RS10495
uniprot id: Q8R830
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

273068:TTE RS10900
gene id: 273068:TTE_RS10900
uniprot id: Q8R7W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

273068:TTE RS04590
gene id: 273068:TTE_RS04590
uniprot id: Q8RB70
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

273068:TTE RS07210
gene id: 273068:TTE_RS07210
uniprot id: Q8R9S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

273068:TTE RS04700
gene id: 273068:TTE_RS04700
uniprot id: Q8RB48
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

273068:TTE RS12295
gene id: 273068:TTE_RS12295
uniprot id: Q8R753
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

273068:TTE RS06280
gene id: 273068:TTE_RS06280
uniprot id: Q8RAA7
names: Similarity
messages: Belongs to the sigma-70 factor family.

273068:TTE RS03025
gene id: 273068:TTE_RS03025
uniprot id: Q8RC24
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

273068:TTE RS05680
gene id: 273068:TTE_RS05680
uniprot id: Q8RAL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

273068:TTE RS08085
gene id: 273068:TTE_RS08085
uniprot id: Q8R9C6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

273068:TTE RS07455
gene id: 273068:TTE_RS07455
uniprot id: Q8R9P1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

273068:TTE RS08035
gene id: 273068:TTE_RS08035
uniprot id: Q8R9D5
names: Similarity
messages: Belongs to the peptidase M18 family.

273068:TTE RS00060
gene id: 273068:TTE_RS00060
uniprot id: Q8RDK6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

273068:TTE RS07080
gene id: 273068:TTE_RS07080
uniprot id: Q8R9V4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

273068:TTE RS00085
gene id: 273068:TTE_RS00085
uniprot id: Q8RDK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

273068:TTE RS02565
gene id: 273068:TTE_RS02565
uniprot id: Q8RC98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

273068:TTE RS10085
gene id: 273068:TTE_RS10085
uniprot id: Q8R8A2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

273068:TTE RS08190
gene id: 273068:TTE_RS08190
uniprot id: Q8R9A6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).