2726185:HGI30 RS03210
gene id: 2726185:HGI30_RS03210
uniprot id: A0A6H2GTE1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2726185:HGI30 RS12970
gene id: 2726185:HGI30_RS12970
uniprot id: A0A6H2GY72
names: Similarity
messages: Belongs to the RemA family.

2726185:HGI30 RS21510
gene id: 2726185:HGI30_RS21510
uniprot id: A0A6H2H3D4
names: Similarity
messages: Belongs to the thioredoxin family.

2726185:HGI30 RS12485
gene id: 2726185:HGI30_RS12485
uniprot id: A0A6H2GY24
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

2726185:HGI30 RS15805
gene id: 2726185:HGI30_RS15805
uniprot id: A0A6H2H0E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2726185:HGI30 RS12265
gene id: 2726185:HGI30_RS12265
uniprot id: A0A6H2GXY4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

2726185:HGI30 RS09090
gene id: 2726185:HGI30_RS09090
uniprot id: A0A6H2GW79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Membrane

2726185:HGI30 RS06235
gene id: 2726185:HGI30_RS06235
uniprot id: A0A6H2GUW2
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

2726185:HGI30 RS13955
gene id: 2726185:HGI30_RS13955
uniprot id: A0A6H2GYY6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2726185:HGI30 RS03025
gene id: 2726185:HGI30_RS03025
uniprot id: A0A6H2GTD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2726185:HGI30 RS01500
gene id: 2726185:HGI30_RS01500
uniprot id: A0A6H2GSM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2726185:HGI30 RS03115
gene id: 2726185:HGI30_RS03115
uniprot id: A0A6H2GTC5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2726185:HGI30 RS00270
gene id: 2726185:HGI30_RS00270
uniprot id: A0A6H2GS22
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2726185:HGI30 RS03055
gene id: 2726185:HGI30_RS03055
uniprot id: A0A6H2GTA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2726185:HGI30 RS03030
gene id: 2726185:HGI30_RS03030
uniprot id: A0A6H2GU29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2726185:HGI30 RS03170
gene id: 2726185:HGI30_RS03170
uniprot id: A0A6H2GTG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2726185:HGI30 RS14195
gene id: 2726185:HGI30_RS14195
uniprot id: A0A6H2GYT7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2726185:HGI30 RS20370
gene id: 2726185:HGI30_RS20370
uniprot id: A0A6H2H1T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

2726185:HGI30 RS02980
gene id: 2726185:HGI30_RS02980
uniprot id: A0A6H2GTB6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2726185:HGI30 RS15795
gene id: 2726185:HGI30_RS15795
uniprot id: A0A6H2GZM2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2726185:HGI30 RS07660
gene id: 2726185:HGI30_RS07660
uniprot id: A0A6H2GW88
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

2726185:HGI30 RS01245
gene id: 2726185:HGI30_RS01245
uniprot id: A0A6H2GT86
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2726185:HGI30 RS12575
gene id: 2726185:HGI30_RS12575
uniprot id: A0A6H2GY33
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2726185:HGI30 RS03180
gene id: 2726185:HGI30_RS03180
uniprot id: A0A6H2GTG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2726185:HGI30 RS03355
gene id: 2726185:HGI30_RS03355
uniprot id: A0A6H2GTI9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2726185:HGI30 RS08910
gene id: 2726185:HGI30_RS08910
uniprot id: A0A6H2GWV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

2726185:HGI30 RS00185
gene id: 2726185:HGI30_RS00185
uniprot id: A0A6H2GRZ4
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

2726185:HGI30 RS10075
gene id: 2726185:HGI30_RS10075
uniprot id: A0A6H2GWR0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2726185:HGI30 RS18665
gene id: 2726185:HGI30_RS18665
uniprot id: A0A6H2H125
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

2726185:HGI30 RS12170
gene id: 2726185:HGI30_RS12170
uniprot id: A0A6H2GY16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2726185:HGI30 RS21140
gene id: 2726185:HGI30_RS21140
uniprot id: A0A6H2H279
names: Similarity
messages: Belongs to the FlgM family.

2726185:HGI30 RS09070
gene id: 2726185:HGI30_RS09070
uniprot id: A0A6H2GW81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

2726185:HGI30 RS03095
gene id: 2726185:HGI30_RS03095
uniprot id: A0A6H2GTB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2726185:HGI30 RS03195
gene id: 2726185:HGI30_RS03195
uniprot id: A0A6H2GTF7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2726185:HGI30 RS10830
gene id: 2726185:HGI30_RS10830
uniprot id: A0A6H2GX69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

2726185:HGI30 RS09060
gene id: 2726185:HGI30_RS09060
uniprot id: A0A6H2GW87
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

2726185:HGI30 RS09045
gene id: 2726185:HGI30_RS09045
uniprot id: A0A6H2GX13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

2726185:HGI30 RS12540
gene id: 2726185:HGI30_RS12540
uniprot id: A0A6H2GYW3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2726185:HGI30 RS03070
gene id: 2726185:HGI30_RS03070
uniprot id: A0A6H2GU21
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2726185:HGI30 RS09125
gene id: 2726185:HGI30_RS09125
uniprot id: A0A6H2GW97
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2726185:HGI30 RS07665
gene id: 2726185:HGI30_RS07665
uniprot id: A0A6H2GVK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2726185:HGI30 RS21060
gene id: 2726185:HGI30_RS21060
uniprot id: A0A6H2H296
names: Subcellular Location Annotation
messages: Cytoplasm

2726185:HGI30 RS09015
gene id: 2726185:HGI30_RS09015
uniprot id: A0A6H2GW75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

2726185:HGI30 RS00535
gene id: 2726185:HGI30_RS00535
uniprot id: A0A6H2GS39
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2726185:HGI30 RS03000
gene id: 2726185:HGI30_RS03000
uniprot id: A0A6H2GT99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2726185:HGI30 RS00165
gene id: 2726185:HGI30_RS00165
uniprot id: A0A6H2GS04
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

2726185:HGI30 RS03100
gene id: 2726185:HGI30_RS03100
uniprot id: A0A6H2GTE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2726185:HGI30 RS15545
gene id: 2726185:HGI30_RS15545
uniprot id: A0A6H2H405
names: Similarity
messages: Belongs to the UPF0297 family.

2726185:HGI30 RS12890
gene id: 2726185:HGI30_RS12890
uniprot id: A0A6H2GY94
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2726185:HGI30 RS03190
gene id: 2726185:HGI30_RS03190
uniprot id: A0A6H2GTJ7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2726185:HGI30 RS07670
gene id: 2726185:HGI30_RS07670
uniprot id: A0A6H2GWC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2726185:HGI30 RS03110
gene id: 2726185:HGI30_RS03110
uniprot id: A0A6H2GTB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2726185:HGI30 RS01845
gene id: 2726185:HGI30_RS01845
uniprot id: A0A6H2GSQ7
names: Subcellular Location Annotation
messages: Cytoplasm

2726185:HGI30 RS03175
gene id: 2726185:HGI30_RS03175
uniprot id: A0A6H2GU40
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2726185:HGI30 RS01445
gene id: 2726185:HGI30_RS01445
uniprot id: A0A6H2GSL3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

2726185:HGI30 RS12045
gene id: 2726185:HGI30_RS12045
uniprot id: A0A6H2GYG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

2726185:HGI30 RS09025
gene id: 2726185:HGI30_RS09025
uniprot id: A0A6H2GW98
names: Subcellular Location Annotation
messages: Membrane

2726185:HGI30 RS12605
gene id: 2726185:HGI30_RS12605
uniprot id: A0A6H2GY28
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2726185:HGI30 RS02985
gene id: 2726185:HGI30_RS02985
uniprot id: A0A6H2GT95
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2726185:HGI30 RS03185
gene id: 2726185:HGI30_RS03185
uniprot id: A0A6H2GU59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2726185:HGI30 RS13530
gene id: 2726185:HGI30_RS13530
uniprot id: A0A6H2GYG9
names: Subcellular Location Annotation
messages: Cytoplasm

2726185:HGI30 RS12190
gene id: 2726185:HGI30_RS12190
uniprot id: A0A6H2GXX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2726185:HGI30 RS09765
gene id: 2726185:HGI30_RS09765
uniprot id: A0A6H2GXA9
names: Similarity
messages: Belongs to the Fur family.

2726185:HGI30 RS14210
gene id: 2726185:HGI30_RS14210
uniprot id: A0A6H2GYU5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2726185:HGI30 RS03125
gene id: 2726185:HGI30_RS03125
uniprot id: A0A6H2GU30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2726185:HGI30 RS08965
gene id: 2726185:HGI30_RS08965
uniprot id: A0A6H2GW59
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2726185:HGI30 RS03045
gene id: 2726185:HGI30_RS03045
uniprot id: A0A6H2GTA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2726185:HGI30 RS08460
gene id: 2726185:HGI30_RS08460
uniprot id: A0A6H2GW45
names: Subcellular Location Annotation
messages: Cytoplasm

2726185:HGI30 RS19885
gene id: 2726185:HGI30_RS19885
uniprot id: A0A6H2H1U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.