272569:RR RS15140
gene id: 272569:RR_RS15140
uniprot id: A0A4V1EMB8
uniprot id: P36174
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
messages: In the N-terminal section; belongs to the KAE1 / TsaD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function.

272569:RR RS09605
gene id: 272569:RR_RS09605
uniprot id: A0A4P8JYN1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

272569:RR RS04975
gene id: 272569:RR_RS04975
uniprot id: A0A4P8JZJ9
uniprot id: Q5V5C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

272569:RR RS10055
gene id: 272569:RR_RS10055
uniprot id: Q5V2F3
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

272569:RR RS07410
gene id: 272569:RR_RS07410
uniprot id: A0A4P8JUD3
uniprot id: Q5V3Z1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS05805
gene id: 272569:RR_RS05805
uniprot id: A0A4V1EMN9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

272569:RR RS11690
gene id: 272569:RR_RS11690
uniprot id: A0A4P8JYX1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS06275
gene id: 272569:RR_RS06275
uniprot id: A0A4P8JSU0
uniprot id: Q5V4L7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

272569:RR RS03075
gene id: 272569:RR_RS03075
uniprot id: Q5V6G5
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS18160
gene id: 272569:RR_RS18160
uniprot id: A0A4P8JYF5
uniprot id: Q5UXW0
names: Caution
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS15410
gene id: 272569:RR_RS15410
uniprot id: A0A4P8JYF8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

272569:RR RS17500
gene id: 272569:RR_RS17500
uniprot id: Q5UY93
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

272569:RR RS05155
gene id: 272569:RR_RS05155
uniprot id: Q5V593
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS19710
gene id: 272569:RR_RS19710
uniprot id: Q5UWZ8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS01765
gene id: 272569:RR_RS01765
uniprot id: Q5V735
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

272569:RR RS09550
gene id: 272569:RR_RS09550
uniprot id: Q5V2R1
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS07035
gene id: 272569:RR_RS07035
uniprot id: Q5V464
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the methylaspartate cycle. Catalyzes the reversible hydration of mesaconyl-CoA (2-methylfumaryl-CoA) to yield beta-methylmalyl-CoA ((2R,3S)-beta-methylmalyl-CoA).

272569:RR RS11625
gene id: 272569:RR_RS11625
uniprot id: Q5V1J3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

272569:RR RS18960
gene id: 272569:RR_RS18960
uniprot id: Q5UXF1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

272569:RR RS10435
gene id: 272569:RR_RS10435
uniprot id: A0A4P8JZ02
names: Similarity
messages: Belongs to the complex I subunit 3 family.

272569:RR RS07020
gene id: 272569:RR_RS07020
uniprot id: A0A4P8JXC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylamine corrinoid protein family.
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

272569:RR RS02575
gene id: 272569:RR_RS02575
uniprot id: Q5V6R7
names: Similarity
messages: Belongs to the arginase family.

272569:RR RS11790
gene id: 272569:RR_RS11790
uniprot id: Q5V1G0
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

272569:RR RS18850
gene id: 272569:RR_RS18850
uniprot id: Q5UXH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

272569:RR RS03510
gene id: 272569:RR_RS03510
uniprot id: A0A4P8JZX9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

272569:RR RS05735
gene id: 272569:RR_RS05735
uniprot id: Q5V4X6
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

272569:RR RS06125
gene id: 272569:RR_RS06125
uniprot id: Q5V4P8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS12320
gene id: 272569:RR_RS12320
uniprot id: A0A4P8K3R1
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS06000
gene id: 272569:RR_RS06000
uniprot id: Q5V4S3
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

272569:RR RS16445
gene id: 272569:RR_RS16445
uniprot id: Q5UYV4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

272569:RR RS11810
gene id: 272569:RR_RS11810
uniprot id: Q5V1F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

272569:RR RS15945
gene id: 272569:RR_RS15945
uniprot id: Q5UZ53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
messages: Cytoplasm

272569:RR RS18120
gene id: 272569:RR_RS18120
uniprot id: A0A4V1EMH4
uniprot id: P19952
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

272569:RR RS18780
gene id: 272569:RR_RS18780
uniprot id: Q5UXI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

272569:RR RS11190
gene id: 272569:RR_RS11190
uniprot id: A0A4P8JZB9
uniprot id: P12732
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Binds to a specific region on the 23S rRNA. Located at the polypeptide exit tunnel on the outside of the subunit.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.
messages: Part of the 50S ribosomal subunit. Interacts with protein L29 and weakly with protein L39e.

272569:RR RS04250
gene id: 272569:RR_RS04250
uniprot id: A0A4P8K0D5
uniprot id: Q5V5R9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS03935
gene id: 272569:RR_RS03935
uniprot id: Q5V5Y7
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS17645
gene id: 272569:RR_RS17645
uniprot id: Q5UY63
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

272569:RR RS05330
gene id: 272569:RR_RS05330
uniprot id: Q5V557
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

272569:RR RS10980
gene id: 272569:RR_RS10980
uniprot id: A0A4P8JYI8
names: Similarity
messages: Belongs to the UPF0175 family.

272569:RR RS04325
gene id: 272569:RR_RS04325
uniprot id: A0A4V1EML1
uniprot id: P05763
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

272569:RR RS20680
gene id: 272569:RR_RS20680
uniprot id: Q5UWE7
names: Similarity
messages: Belongs to the leucine-binding protein family.

272569:RR RS16175
gene id: 272569:RR_RS16175
uniprot id: A0A4P8JYL9
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS19530
gene id: 272569:RR_RS19530
uniprot id: Q5UX35
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

272569:RR RS17830
gene id: 272569:RR_RS17830
uniprot id: A0A4P8K2J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

272569:RR RS08895
gene id: 272569:RR_RS08895
uniprot id: Q5V345
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

272569:RR RS16595
gene id: 272569:RR_RS16595
uniprot id: A0A4P8JYT5
uniprot id: Q5UYS2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

272569:RR RS11165
gene id: 272569:RR_RS11165
uniprot id: A0A4P8K386
uniprot id: P10971
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Part of the 50S ribosomal subunit. Interacts with protein L23.
messages: Stabilizes the tertiary rRNA structure within the 23S rRNA domain (domain I) to which it binds. Located at the polypeptide exit tunnel on the outside of the subunit.

272569:RR RS12745
gene id: 272569:RR_RS12745
uniprot id: Q5V0X0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.
messages: Divalent cations. Mg(2+) and to a lesser extent, Mn(2+), Co(2+) and Ca(2+).
messages: Involved in the methylaspartate cycle. Catalyzes the biosynthesis of malate in two steps. In the first reaction acetyl-CoA is condensed reversibly with glyoxylate to form (S)-malyl-CoA. In the second reaction (S)-malyl-CoA is hydrolyzed to malate and CoA. It can also catalyzes the condensation of propionyl-CoA with glyoxylate and of acetyl-CoA with pyruvate, however the CoA-ester hydrolysis reaction is highly specific for (S)-malyl-CoA.

272569:RR RS11225
gene id: 272569:RR_RS11225
uniprot id: Q5V1S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

272569:RR RS20890
gene id: 272569:RR_RS20890
uniprot id: Q5UWA3
names: Subcellular Location Annotation
messages: Cytoplasm

272569:RR RS11195
gene id: 272569:RR_RS11195
uniprot id: A0A4P8JYM2
uniprot id: P12735
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel, in which it helps forms a bend with protein L22. Contacts the macrolide antibiotic spiramycin in the polypeptide exit tunnel.
messages: Forms part of the polypeptide exit tunnel.
messages: Makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly (By similarity).
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.
messages: Part of the 50S ribosomal subunit. Interacts weakly with proteins L18e, L24 and L37e. Has been cross-linked to L18e.

272569:RR RS11980
gene id: 272569:RR_RS11980
uniprot id: A0A4P8JVC0
uniprot id: Q5V1C1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS04275
gene id: 272569:RR_RS04275
uniprot id: Q5V5R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

272569:RR RS13090
gene id: 272569:RR_RS13090
uniprot id: Q5V0Q3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS16470
gene id: 272569:RR_RS16470
uniprot id: A0A4V1EME3
names: Similarity
messages: Belongs to the UPF0215 family.

272569:RR RS16605
gene id: 272569:RR_RS16605
uniprot id: Q5UYS0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

272569:RR RS08400
gene id: 272569:RR_RS08400
uniprot id: Q5V3E4
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS14250
gene id: 272569:RR_RS14250
uniprot id: A0A4P8JYT3
uniprot id: Q5V030
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

272569:RR RS02970
gene id: 272569:RR_RS02970
uniprot id: Q5V6I8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS14805
gene id: 272569:RR_RS14805
uniprot id: Q5UZS2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

272569:RR RS02380
gene id: 272569:RR_RS02380
uniprot id: Q5V6V7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

272569:RR RS12515
gene id: 272569:RR_RS12515
uniprot id: Q5V112
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

272569:RR RS02430
gene id: 272569:RR_RS02430
uniprot id: Q5V6U7
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

272569:RR RS11710
gene id: 272569:RR_RS11710
uniprot id: A0A4P8JWG7
uniprot id: Q5V1H7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Binds two Mg(2+) per subunit.
messages: Forms a ternary complex with MCM helicase and DNA.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

272569:RR RS07170
gene id: 272569:RR_RS07170
uniprot id: Q5V437
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS18180
gene id: 272569:RR_RS18180
uniprot id: Q5UXV5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS07670
gene id: 272569:RR_RS07670
uniprot id: A0A4P8JWY4
uniprot id: Q03302
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

272569:RR RS03515
gene id: 272569:RR_RS03515
uniprot id: A0A4V1ELR3
names: Subcellular Location Annotation
messages: Cytoplasm

272569:RR RS17420
gene id: 272569:RR_RS17420
uniprot id: Q5UYB0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

272569:RR RS16310
gene id: 272569:RR_RS16310
uniprot id: Q5UYX8
names: Subcellular Location Annotation
messages: Nucleus

272569:RR RS18530
gene id: 272569:RR_RS18530
uniprot id: Q5UXN6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS17180
gene id: 272569:RR_RS17180
uniprot id: Q5UYF2
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS12460
gene id: 272569:RR_RS12460
uniprot id: A0A4P8JXX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

272569:RR RS01085
gene id: 272569:RR_RS01085
uniprot id: Q5V7M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

272569:RR RS17195
gene id: 272569:RR_RS17195
uniprot id: A0A4P8JZ33
names: Function
messages: Protects DNA against thermal denaturation and modulates transcription.

272569:RR RS17915
gene id: 272569:RR_RS17915
uniprot id: Q5UY10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

272569:RR RS19355
gene id: 272569:RR_RS19355
uniprot id: Q5UX71
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

272569:RR RS18520
gene id: 272569:RR_RS18520
uniprot id: Q5UXN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

272569:RR RS05855
gene id: 272569:RR_RS05855
uniprot id: Q5V4V2
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS19120
gene id: 272569:RR_RS19120
uniprot id: A0A4P8JYU6
uniprot id: Q5UXB8
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

272569:RR RS12700
gene id: 272569:RR_RS12700
uniprot id: Q5V0X9
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

272569:RR RS17685
gene id: 272569:RR_RS17685
uniprot id: A0A4P8JZB3
uniprot id: Q5UY54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

272569:RR RS17115
gene id: 272569:RR_RS17115
uniprot id: Q5UYG4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

272569:RR RS14835
gene id: 272569:RR_RS14835
uniprot id: Q5UZR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

272569:RR RS08940
gene id: 272569:RR_RS08940
uniprot id: A0A4P8JV87
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS08120
gene id: 272569:RR_RS08120
uniprot id: A0A4P8JTN3
uniprot id: Q5V3K1
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

272569:RR RS09205
gene id: 272569:RR_RS09205
uniprot id: Q5V2Y0
names: Similarity
messages: Belongs to the FUN14 family.

272569:RR RS04675
gene id: 272569:RR_RS04675
uniprot id: A0A4P8K385
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS14905
gene id: 272569:RR_RS14905
uniprot id: Q5UZQ5
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

272569:RR RS17540
gene id: 272569:RR_RS17540
uniprot id: A0A4P8K6C6
uniprot id: Q5UY84
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS00820
gene id: 272569:RR_RS00820
uniprot id: Q5V7X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

272569:RR RS03300
gene id: 272569:RR_RS03300
uniprot id: A0A4P8JWQ6
uniprot id: Q5V6B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system (By similarity).
messages: The complex is composed of two ATP-binding proteins (PhnC), two transmembrane proteins (PhnE) and a solute-binding protein (PhnD).

272569:RR RS17165
gene id: 272569:RR_RS17165
uniprot id: Q5UYF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm

272569:RR RS02425
gene id: 272569:RR_RS02425
uniprot id: Q5V6U8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

272569:RR RS18040
gene id: 272569:RR_RS18040
uniprot id: A0A4P8K234
uniprot id: Q5UXY5
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

272569:RR RS07820
gene id: 272569:RR_RS07820
uniprot id: A0A4P8JXS7
uniprot id: Q5V3R0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

272569:RR RS17105
gene id: 272569:RR_RS17105
uniprot id: A0A4P8JXU4
uniprot id: Q5UYG6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: The active site is a redox-active disulfide bond.

272569:RR RS14475
gene id: 272569:RR_RS14475
uniprot id: Q5UZY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS14820
gene id: 272569:RR_RS14820
uniprot id: A0A4V1EMB2
uniprot id: P32552
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

272569:RR RS18585
gene id: 272569:RR_RS18585
uniprot id: Q5UXM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

272569:RR RS05105
gene id: 272569:RR_RS05105
uniprot id: A0A4P8K0Q7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

272569:RR RS15290
gene id: 272569:RR_RS15290
uniprot id: Q5UZH9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS10805
gene id: 272569:RR_RS10805
uniprot id: Q5V205
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

272569:RR RS16775
gene id: 272569:RR_RS16775
uniprot id: A0A4V1EME9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS10285
gene id: 272569:RR_RS10285
uniprot id: A0A4P8JVU1
uniprot id: P15772
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

272569:RR RS11665
gene id: 272569:RR_RS11665
uniprot id: Q5V1I6
names: Similarity
messages: Belongs to the Ahb/Nir family.

272569:RR RS10350
gene id: 272569:RR_RS10350
uniprot id: A0A4P8JUT0
uniprot id: Q5V296
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

272569:RR RS18285
gene id: 272569:RR_RS18285
uniprot id: Q5UXT3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

272569:RR RS18115
gene id: 272569:RR_RS18115
uniprot id: Q5UXW9
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS10740
gene id: 272569:RR_RS10740
uniprot id: A0A4V1EM34
uniprot id: Q5V216
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

272569:RR RS16060
gene id: 272569:RR_RS16060
uniprot id: A0A4P8K148
uniprot id: Q07841
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Cytoplasm
messages: Homotetramer; arranged as a dimer of dimers.
messages: The quaternary structure is stabilized by chloride ions bound between the subunits. This may be an adaptation to the halophilic environment.

272569:RR RS16800
gene id: 272569:RR_RS16800
uniprot id: A0A4P8K1H7
uniprot id: Q5UYM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

272569:RR RS11925
gene id: 272569:RR_RS11925
uniprot id: A0A4P8JWT3
uniprot id: Q5V1D1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS06375
gene id: 272569:RR_RS06375
uniprot id: Q5V4J6
names: Similarity
messages: Belongs to the HerA family.

272569:RR RS18360
gene id: 272569:RR_RS18360
uniprot id: Q5UXR8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

272569:RR RS05110
gene id: 272569:RR_RS05110
uniprot id: Q5V5A2
names: Function
messages: Part of a potassium transport system.

272569:RR RS11160
gene id: 272569:RR_RS11160
uniprot id: A0A4P8JV46
uniprot id: P22527
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

272569:RR RS09025
gene id: 272569:RR_RS09025
uniprot id: Q5V318
names: Subcellular Location Annotation
messages: Cytoplasm

272569:RR RS10070
gene id: 272569:RR_RS10070
uniprot id: Q5V2F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

272569:RR RS12375
gene id: 272569:RR_RS12375
uniprot id: A0A4P8K3S0
uniprot id: Q5V140
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

272569:RR RS17810
gene id: 272569:RR_RS17810
uniprot id: A0A4V1EMG8
uniprot id: P22452
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL39 family.
messages: Binds to the 23S rRNA. Forms part of the polypeptide exit tunnel.
messages: Part of the 50S ribosomal subunit. Interacts weakly with protein L23.

272569:RR RS04810
gene id: 272569:RR_RS04810
uniprot id: A0A4V1EMM0
names: Similarity
messages: Belongs to the peptidase S9C family.

272569:RR RS03775
gene id: 272569:RR_RS03775
uniprot id: Q5V624
names: Similarity
messages: Belongs to the RutC family.

272569:RR RS17620
gene id: 272569:RR_RS17620
uniprot id: Q5UY68
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

272569:RR RS13150
gene id: 272569:RR_RS13150
uniprot id: Q5V0P1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

272569:RR RS16700
gene id: 272569:RR_RS16700
uniprot id: Q5UYQ0
names: Subunit
messages: Homotrimer.

272569:RR RS02830
gene id: 272569:RR_RS02830
uniprot id: A0A4P8JVT0
uniprot id: Q75ZQ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

272569:RR RS17055
gene id: 272569:RR_RS17055
uniprot id: Q5UYH7
names: Caution
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS11110
gene id: 272569:RR_RS11110
uniprot id: A0A4P8JV38
uniprot id: P14119
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Binds to the 23S rRNA. Located at the polypeptide exit tunnel on the outside of the subunit.
messages: Part of the 50S ribosomal subunit.

272569:RR RS13430
gene id: 272569:RR_RS13430
uniprot id: Q5V0I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cell membrane
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Membrane
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

272569:RR RS07255
gene id: 272569:RR_RS07255
uniprot id: Q5V420
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

272569:RR RS16145
gene id: 272569:RR_RS16145
uniprot id: Q5UZ10
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

272569:RR RS07080
gene id: 272569:RR_RS07080
uniprot id: Q5V455
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

272569:RR RS19595
gene id: 272569:RR_RS19595
uniprot id: A0A4P8K2N1
uniprot id: P32411
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Binds to the 23S rRNA. Binds deacetylated tRNA in the E site; when the tRNA binds a stretch of 7 amino acids are displaced to allow binding.
messages: Part of the 50S ribosomal subunit.
messages: Part of the 50S ribosomal subunit. Interacts weakly with protein L15e. Binds the E site tRNA.

272569:RR RS20060
gene id: 272569:RR_RS20060
uniprot id: Q5UWS6
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

272569:RR RS10480
gene id: 272569:RR_RS10480
uniprot id: Q5V270
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

272569:RR RS06345
gene id: 272569:RR_RS06345
uniprot id: A0A4P8K0Z5
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.

272569:RR RS07300
gene id: 272569:RR_RS07300
uniprot id: Q5V413
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

272569:RR RS07920
gene id: 272569:RR_RS07920
uniprot id: Q5V3P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

272569:RR RS12860
gene id: 272569:RR_RS12860
uniprot id: Q5V0U7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS12835
gene id: 272569:RR_RS12835
uniprot id: Q5V0V2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

272569:RR RS20565
gene id: 272569:RR_RS20565
uniprot id: A0A4P8JVT7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

272569:RR RS05775
gene id: 272569:RR_RS05775
uniprot id: Q5V4W8
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS15940
gene id: 272569:RR_RS15940
uniprot id: Q5UZ54
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS08335
gene id: 272569:RR_RS08335
uniprot id: Q5V3F9
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

272569:RR RS12035
gene id: 272569:RR_RS12035
uniprot id: Q5V1B1
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS14540
gene id: 272569:RR_RS14540
uniprot id: Q5UZX3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

272569:RR RS03905
gene id: 272569:RR_RS03905
uniprot id: Q5V5Z4
names: Similarity
messages: Belongs to the GcvT family.

272569:RR RS03745
gene id: 272569:RR_RS03745
uniprot id: A0A4V1ELR7
uniprot id: Q5V630
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

272569:RR RS16745
gene id: 272569:RR_RS16745
uniprot id: A0A4P8K1G7
uniprot id: Q5UYP1
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

272569:RR RS15425
gene id: 272569:RR_RS15425
uniprot id: A0A4P8K1T9
names: Similarity
messages: Belongs to the IMPACT family.

272569:RR RS21020
gene id: 272569:RR_RS21020
uniprot id: Q5UW76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS02705
gene id: 272569:RR_RS02705
uniprot id: Q5V6P1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

272569:RR RS18505
gene id: 272569:RR_RS18505
uniprot id: Q5UXP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS16640
gene id: 272569:RR_RS16640
uniprot id: A0A4P8JZX5
uniprot id: Q5UYR3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS16845
gene id: 272569:RR_RS16845
uniprot id: Q5UYM0
names: Biotechnology
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PHA/PHB synthase family.
messages: Heterodimer with PhaE.
messages: Involved in the production of polyhydroxyalkonic acids (PHAs), which are water-insoluble biopolymers used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. PHAs are composed primarily of 3-hydroxybutyric acid (3HB) and 3-hydroxyvaleric acid (3HV). Required for the production of poly-beta-hydroxybutyrate (PHB) and poly(beta-hydroxybutyrate-co-beta-hydroxyvalerate) (PHBV).
messages: PHB and PHBV are desirable bioplastic due to their biodegradability, biocompatibility, and mechanical properties. However, PHBV has better mechanical properties than PHB.

272569:RR RS04940
gene id: 272569:RR_RS04940
uniprot id: A0A4P8K3B8
uniprot id: Q5V5D4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

272569:RR RS13275
gene id: 272569:RR_RS13275
uniprot id: Q5V0L6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS04760
gene id: 272569:RR_RS04760
uniprot id: A0A4V1EML9
uniprot id: Q5V5H0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

272569:RR RS12705
gene id: 272569:RR_RS12705
uniprot id: A0A4P8JZF5
names: Similarity
messages: Belongs to the disproportionating enzyme family.

272569:RR RS05115
gene id: 272569:RR_RS05115
uniprot id: Q5V5A1
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS05755
gene id: 272569:RR_RS05755
uniprot id: Q5V4X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm

272569:RR RS13545
gene id: 272569:RR_RS13545
uniprot id: A0A4V1EM87
uniprot id: Q5V0G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

272569:RR RS14885
gene id: 272569:RR_RS14885
uniprot id: Q5UZQ8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

272569:RR RS02395
gene id: 272569:RR_RS02395
uniprot id: Q5V6V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS17800
gene id: 272569:RR_RS17800
uniprot id: Q5UY32
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS18555
gene id: 272569:RR_RS18555
uniprot id: A0A4P8K3R4
uniprot id: Q5UXN1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofH family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: Consists of two subunits, CofG and CofH.
messages: The FO synthase complex consists of two subunits, CofG and CofH.

272569:RR RS19585
gene id: 272569:RR_RS19585
uniprot id: A0A4P8K0F3
uniprot id: Q5UX22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-alpha family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

272569:RR RS20740
gene id: 272569:RR_RS20740
uniprot id: Q5UWD4
names: Similarity
messages: Belongs to the thioesterase PaaI family.

272569:RR RS20850
gene id: 272569:RR_RS20850
uniprot id: Q5UWB1
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS05910
gene id: 272569:RR_RS05910
uniprot id: Q5V4U1
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS10640
gene id: 272569:RR_RS10640
uniprot id: Q5V238
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

272569:RR RS04360
gene id: 272569:RR_RS04360
uniprot id: Q5V5P9
names: Similarity
messages: Belongs to the cytochrome P450 family.

272569:RR RS18475
gene id: 272569:RR_RS18475
uniprot id: Q5UXP6
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

272569:RR RS17350
gene id: 272569:RR_RS17350
uniprot id: Q5UYC5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

272569:RR RS10845
gene id: 272569:RR_RS10845
uniprot id: A0A4V1EM36
names: Function
messages: Part of a potassium transport system.

272569:RR RS10655
gene id: 272569:RR_RS10655
uniprot id: Q5V234
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS08385
gene id: 272569:RR_RS08385
uniprot id: Q5V3E7
names: Similarity
messages: Belongs to the Nth/MutY family.

272569:RR RS09495
gene id: 272569:RR_RS09495
uniprot id: A0A4P8JWL5
uniprot id: Q5V2S1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

272569:RR RS14020
gene id: 272569:RR_RS14020
uniprot id: A0A4P8K033
uniprot id: Q5V069
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

272569:RR RS18005
gene id: 272569:RR_RS18005
uniprot id: Q5UXZ2
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS06030
gene id: 272569:RR_RS06030
uniprot id: Q5V4R7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

272569:RR RS11120
gene id: 272569:RR_RS11120
uniprot id: A0A4V1EM41
uniprot id: P14135
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: Part of the 50S ribosomal subunit. Interacts weakly with protein L13.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

272569:RR RS11240
gene id: 272569:RR_RS11240
uniprot id: A0A4P8JYP2
uniprot id: Q5V1R7
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

272569:RR RS12560
gene id: 272569:RR_RS12560
uniprot id: Q5V104
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

272569:RR RS20015
gene id: 272569:RR_RS20015
uniprot id: Q5UWT7
names: Similarity
messages: Belongs to the UPF0175 family.

272569:RR RS08845
gene id: 272569:RR_RS08845
uniprot id: Q5V356
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

272569:RR RS15980
gene id: 272569:RR_RS15980
uniprot id: A0A4V1EMD4
uniprot id: Q5UZ46
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS19580
gene id: 272569:RR_RS19580
uniprot id: A0A4V1EMK2
uniprot id: Q5UX23
names: Function
names: Similarity
messages: Belongs to the NOP10 family.
messages: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.

272569:RR RS15320
gene id: 272569:RR_RS15320
uniprot id: Q5UZH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

272569:RR RS15675
gene id: 272569:RR_RS15675
uniprot id: Q5UZA4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

272569:RR RS07025
gene id: 272569:RR_RS07025
uniprot id: A0A4P8JWM7
uniprot id: Q5V466
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS15310
gene id: 272569:RR_RS15310
uniprot id: Q5UZH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family. Archaeal preflagellin peptidase subfamily.
messages: Cell membrane
messages: Cleaves the N-terminal leader peptide from preflagellins.

272569:RR RS07660
gene id: 272569:RR_RS07660
uniprot id: Q5V3U1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS12315
gene id: 272569:RR_RS12315
uniprot id: Q5V152
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS09005
gene id: 272569:RR_RS09005
uniprot id: A0A4V1EM02
uniprot id: Q5V323
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

272569:RR RS12340
gene id: 272569:RR_RS12340
uniprot id: Q5V147
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

272569:RR RS03925
gene id: 272569:RR_RS03925
uniprot id: Q5V5Z0
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

272569:RR RS13130
gene id: 272569:RR_RS13130
uniprot id: Q5V0P5
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

272569:RR RS07650
gene id: 272569:RR_RS07650
uniprot id: A0A4P8JUW7
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS10835
gene id: 272569:RR_RS10835
uniprot id: A0A4P8JUZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

272569:RR RS07495
gene id: 272569:RR_RS07495
uniprot id: Q5V3X3
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

272569:RR RS19700
gene id: 272569:RR_RS19700
uniprot id: A0A4V1EMK4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS09430
gene id: 272569:RR_RS09430
uniprot id: A0A4P8JXW8
uniprot id: Q5V2T4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

272569:RR RS20980
gene id: 272569:RR_RS20980
uniprot id: Q5UW84
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS04550
gene id: 272569:RR_RS04550
uniprot id: A0A4P8JZD3
names: Function
names: Similarity
messages: Belongs to the archaeal-type GTP cyclohydrolase family.
messages: Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.

272569:RR RS18190
gene id: 272569:RR_RS18190
uniprot id: Q5UXV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS16495
gene id: 272569:RR_RS16495
uniprot id: A0A4P8JZU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS16450
gene id: 272569:RR_RS16450
uniprot id: A0A4P8JZU2
uniprot id: Q5UYV3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

272569:RR RS02440
gene id: 272569:RR_RS02440
uniprot id: A0A4P8JWA2
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS13185
gene id: 272569:RR_RS13185
uniprot id: Q5V0N4
names: Similarity
messages: Belongs to the AOR/FOR family.

272569:RR RS04070
gene id: 272569:RR_RS04070
uniprot id: Q5V5V7
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS08925
gene id: 272569:RR_RS08925
uniprot id: Q5V340
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

272569:RR RS07115
gene id: 272569:RR_RS07115
uniprot id: A0A4V1ELW6
uniprot id: Q5V448
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component I catalyzes the formation of anthranilate using ammonia rather than glutamine, whereas component II provides glutamine amidotransferase activity.
messages: Tetramer of two components I and two components II.

272569:RR RS05150
gene id: 272569:RR_RS05150
uniprot id: Q5V594
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS00925
gene id: 272569:RR_RS00925
uniprot id: A0A4P8JUW4
uniprot id: Q5V7I2
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

272569:RR RS03815
gene id: 272569:RR_RS03815
uniprot id: A0A4P8JW34
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS20030
gene id: 272569:RR_RS20030
uniprot id: A0A4P8JZJ3
uniprot id: Q5UWT2
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

272569:RR RS07105
gene id: 272569:RR_RS07105
uniprot id: A0A4P8JT76
uniprot id: Q5V450
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS11175
gene id: 272569:RR_RS11175
uniprot id: A0A4P8JWF6
uniprot id: P10970
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Contacts all 6 domains of the 23S rRNA, helping stabilize their relative orientation. An extended beta-hairpin in the C-terminus forms part of the polypeptide exit tunnel, in which it helps forms a bend with protein L4, while most of the rest of the protein is located at the polypeptide exit tunnel on the outside of the subunit.
messages: Part of the 50S ribosomal subunit.
messages: Part of the 50S ribosomal subunit. Contacts the macrolide antibiotic tylosin in the polypeptide exit tunnel.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

272569:RR RS03625
gene id: 272569:RR_RS03625
uniprot id: Q5V654
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

272569:RR RS15845
gene id: 272569:RR_RS15845
uniprot id: Q5UZ73
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

272569:RR RS11125
gene id: 272569:RR_RS11125
uniprot id: A0A4P8JWE7
uniprot id: P12742
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

272569:RR RS01375
gene id: 272569:RR_RS01375
uniprot id: A0A4P8JTB5
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

272569:RR RS10445
gene id: 272569:RR_RS10445
uniprot id: Q5V277
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

272569:RR RS10670
gene id: 272569:RR_RS10670
uniprot id: A0A4P8JUX8
uniprot id: Q5V231
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

272569:RR RS11390
gene id: 272569:RR_RS11390
uniprot id: Q5V1N8
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS05195
gene id: 272569:RR_RS05195
uniprot id: A0A4P8K3F1
uniprot id: P12734
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL21 family.
messages: Part of the 50S ribosomal subunit. Interacts with protein L18 and binds the 5S rRNA. Has been cross-linked to L18.
messages: This is one of 5 proteins that mediate the attachment of the 5S rRNA onto the large ribosomal subunit, stabilizing the orientation of adjacent RNA domains.

272569:RR RS01795
gene id: 272569:RR_RS01795
uniprot id: Q5V738
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS16805
gene id: 272569:RR_RS16805
uniprot id: Q5UYM8
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

272569:RR RS06445
gene id: 272569:RR_RS06445
uniprot id: Q5V4I3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

272569:RR RS03060
gene id: 272569:RR_RS03060
uniprot id: A0A4P8JU69
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS14545
gene id: 272569:RR_RS14545
uniprot id: Q5UZX2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

272569:RR RS15565
gene id: 272569:RR_RS15565
uniprot id: A0A4P8JYI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

272569:RR RS01925
gene id: 272569:RR_RS01925
uniprot id: Q5V778
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS11565
gene id: 272569:RR_RS11565
uniprot id: Q5V1K4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

272569:RR RS08315
gene id: 272569:RR_RS08315
uniprot id: Q5V3G3
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.

272569:RR RS06450
gene id: 272569:RR_RS06450
uniprot id: Q5V4I2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

272569:RR RS14840
gene id: 272569:RR_RS14840
uniprot id: A0A4P8K1J1
uniprot id: Q5UZR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

272569:RR RS07930
gene id: 272569:RR_RS07930
uniprot id: Q5V3P0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A 'suicide' enzyme that participates in biotin synthesis. Catalyzes the formation of (S)-8-amino-7-oxononanoate (DAN-carbamic acid) from (7R,8S)-8-amino-7-(carboxyamino)nonanoate (DAN), a function equivalent to the cannonical BioA reaction and the first half-reaction of BioD. The cellular requirement for biotin is thought be low enough that this single turnover enzyme supplies a sufficient amount of the cofactor. Overall it catalyzes three reactions: formation of a covalent linkage with 8-amino-7-oxononanoate to yield a BioU-DAN conjugate at the epsilon-amino group of Lys124 of BioU using NAD(P)H, carboxylation of the conjugate to form BioU-DAN-carbamic acid, and release of DAN-carbamic acid using NAD(P)+.
messages: Belongs to the BioU family.
messages: In cannonical biotin synthesis a pimeloyl-conjugate is transformed into biotin by the subsequent action of BioF, BioA, BioD and BioB. This enzyme replaces BioA and performs the first half-reaction of BioD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

272569:RR RS20585
gene id: 272569:RR_RS20585
uniprot id: A0A4P8JRP9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS09960
gene id: 272569:RR_RS09960
uniprot id: Q5V2H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

272569:RR RS17185
gene id: 272569:RR_RS17185
uniprot id: A0A4P8K1N7
uniprot id: Q5UYF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

272569:RR RS03500
gene id: 272569:RR_RS03500
uniprot id: Q5V678
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS05520
gene id: 272569:RR_RS05520
uniprot id: A0A4P8K0W2
uniprot id: Q5V520
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS13085
gene id: 272569:RR_RS13085
uniprot id: Q5V0Q4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS09255
gene id: 272569:RR_RS09255
uniprot id: A0A4P8JU77
uniprot id: Q5V2X0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

272569:RR RS07165
gene id: 272569:RR_RS07165
uniprot id: A0A4V1ELW7
names: Similarity
messages: Belongs to the DNA photolyase family.

272569:RR RS06960
gene id: 272569:RR_RS06960
uniprot id: Q5V479
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

272569:RR RS11605
gene id: 272569:RR_RS11605
uniprot id: Q5V1J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

272569:RR RS17150
gene id: 272569:RR_RS17150
uniprot id: Q5UYF8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

272569:RR RS19590
gene id: 272569:RR_RS19590
uniprot id: A0A4P8JZ24
uniprot id: Q5UX21
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

272569:RR RS09200
gene id: 272569:RR_RS09200
uniprot id: A0A4P8JVC6
uniprot id: O59651
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS07520
gene id: 272569:RR_RS07520
uniprot id: Q5V3W8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

272569:RR RS20815
gene id: 272569:RR_RS20815
uniprot id: Q5UWB8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

272569:RR RS03490
gene id: 272569:RR_RS03490
uniprot id: Q5V680
names: Subcellular Location Annotation
messages: Cytoplasm

272569:RR RS05705
gene id: 272569:RR_RS05705
uniprot id: Q5V4Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

272569:RR RS15950
gene id: 272569:RR_RS15950
uniprot id: Q5UZ52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

272569:RR RS05175
gene id: 272569:RR_RS05175
uniprot id: Q5V589
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

272569:RR RS02840
gene id: 272569:RR_RS02840
uniprot id: A0A4P8JTD2
uniprot id: Q75ZQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

272569:RR RS04500
gene id: 272569:RR_RS04500
uniprot id: A0A4P8K367
uniprot id: Q5V5M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

272569:RR RS20995
gene id: 272569:RR_RS20995
uniprot id: A0A4P8JVC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

272569:RR RS13415
gene id: 272569:RR_RS13415
uniprot id: A0A4P8K0H3
uniprot id: Q5V0I9
names: Function
names: Similarity
messages: Belongs to the FAU-1 family.
messages: Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.

272569:RR RS12690
gene id: 272569:RR_RS12690
uniprot id: Q5V0Y1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

272569:RR RS04380
gene id: 272569:RR_RS04380
uniprot id: Q5V5P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Homodimer.

272569:RR RS02405
gene id: 272569:RR_RS02405
uniprot id: Q5V6V2
names: Subunit
messages: Homotetramer.

272569:RR RS09220
gene id: 272569:RR_RS09220
uniprot id: A0A4P8JVM5
uniprot id: Q5V2X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

272569:RR RS18910
gene id: 272569:RR_RS18910
uniprot id: Q5UXG1
names: Subcellular Location Annotation
messages: Cytoplasm

272569:RR RS11185
gene id: 272569:RR_RS11185
uniprot id: A0A4P8JYN3
uniprot id: P20276
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome (By similarity).
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome (By similarity). Interacts weakly with protein L37Ae.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This protein can be partially incorporated into E.coli polysomes in vivo, indicating it can replace the endogenous protein.

272569:RR RS15125
gene id: 272569:RR_RS15125
uniprot id: Q5UZL1
names: Similarity
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.

272569:RR RS08600
gene id: 272569:RR_RS08600
uniprot id: A0A4P8JV45
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

272569:RR RS05180
gene id: 272569:RR_RS05180
uniprot id: A0A4P8JZN4
uniprot id: Q5V588
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

272569:RR RS00830
gene id: 272569:RR_RS00830
uniprot id: Q5V7G2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS03395
gene id: 272569:RR_RS03395
uniprot id: A0A4P8JSM6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS09230
gene id: 272569:RR_RS09230
uniprot id: A0A4P8JXT5
uniprot id: Q5V2X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

272569:RR RS02880
gene id: 272569:RR_RS02880
uniprot id: Q5V6K6
names: Subcellular Location Annotation
messages: Cytoplasm

272569:RR RS19400
gene id: 272569:RR_RS19400
uniprot id: A0A4P8K053
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS16385
gene id: 272569:RR_RS16385
uniprot id: A0A4P8K1A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

272569:RR RS06940
gene id: 272569:RR_RS06940
uniprot id: Q5V483
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS02795
gene id: 272569:RR_RS02795
uniprot id: A0A4P8JSQ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS05985
gene id: 272569:RR_RS05985
uniprot id: A0A4P8K3S3
uniprot id: Q5V4S6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

272569:RR RS04670
gene id: 272569:RR_RS04670
uniprot id: Q5V5I8
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS18295
gene id: 272569:RR_RS18295
uniprot id: A0A4P8K0Q5
uniprot id: Q5UXT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).
messages: Cell membrane
messages: Membrane

272569:RR RS16675
gene id: 272569:RR_RS16675
uniprot id: Q5UYQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

272569:RR RS10790
gene id: 272569:RR_RS10790
uniprot id: Q5V208
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS15870
gene id: 272569:RR_RS15870
uniprot id: A0A4P8K5P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

272569:RR RS14745
gene id: 272569:RR_RS14745
uniprot id: A0A4P8JZ13
uniprot id: P23357
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

272569:RR RS10235
gene id: 272569:RR_RS10235
uniprot id: A0A4P8JVT3
uniprot id: Q5V2B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

272569:RR RS05505
gene id: 272569:RR_RS05505
uniprot id: A0A4P8K536
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

272569:RR RS02975
gene id: 272569:RR_RS02975
uniprot id: Q5V6I7
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

272569:RR RS14320
gene id: 272569:RR_RS14320
uniprot id: Q5V017
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS08370
gene id: 272569:RR_RS08370
uniprot id: A0A4P8JV90
uniprot id: Q5V3F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylamine corrinoid protein family.
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

272569:RR RS13795
gene id: 272569:RR_RS13795
uniprot id: A0A4P8K4J2
uniprot id: Q5V0B3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

272569:RR RS16515
gene id: 272569:RR_RS16515
uniprot id: A0A4V1EME4
uniprot id: P54221
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer (By similarity).
messages: Homodimer. The tRNA molecule binds across the dimer.

272569:RR RS06065
gene id: 272569:RR_RS06065
uniprot id: A0A4P8JTR8
uniprot id: Q5V4R0
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

272569:RR RS05725
gene id: 272569:RR_RS05725
uniprot id: Q5V4X8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

272569:RR RS11420
gene id: 272569:RR_RS11420
uniprot id: A0A4P8JZF4
uniprot id: Q5V1N2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS15710
gene id: 272569:RR_RS15710
uniprot id: Q5UZ98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

272569:RR RS17515
gene id: 272569:RR_RS17515
uniprot id: A0A4P8K1U3
uniprot id: Q5UY89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

272569:RR RS14895
gene id: 272569:RR_RS14895
uniprot id: Q5UZQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mer family.
messages: Catalyzes the oxidation of methyl-H(4)MPT to methylene-H(4)MPT.
messages: Cytoplasm

272569:RR RS13555
gene id: 272569:RR_RS13555
uniprot id: Q5V0G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

272569:RR RS15180
gene id: 272569:RR_RS15180
uniprot id: A0A4P8JX14
uniprot id: Q5UZJ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

272569:RR RS14160
gene id: 272569:RR_RS14160
uniprot id: Q5V045
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

272569:RR RS19680
gene id: 272569:RR_RS19680
uniprot id: Q5UX04
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS06855
gene id: 272569:RR_RS06855
uniprot id: Q5V4A1
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS00825
gene id: 272569:RR_RS00825
uniprot id: A0A4P8JYX0
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS08425
gene id: 272569:RR_RS08425
uniprot id: A0A4P8JTT8
uniprot id: Q5V3D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

272569:RR RS17910
gene id: 272569:RR_RS17910
uniprot id: Q5UY11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

272569:RR RS00565
gene id: 272569:RR_RS00565
uniprot id: Q5V814
names: Similarity
messages: Belongs to the MCM family.

272569:RR RS10675
gene id: 272569:RR_RS10675
uniprot id: A0A4P8K310
uniprot id: Q5V230
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

272569:RR RS17795
gene id: 272569:RR_RS17795
uniprot id: Q5UY33
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

272569:RR RS12810
gene id: 272569:RR_RS12810
uniprot id: Q5V0V6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

272569:RR RS05120
gene id: 272569:RR_RS05120
uniprot id: Q5V5A0
names: Function
messages: Part of a potassium transport system.

272569:RR RS09120
gene id: 272569:RR_RS09120
uniprot id: Q5V2Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

272569:RR RS13510
gene id: 272569:RR_RS13510
uniprot id: Q5V0H0
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS08265
gene id: 272569:RR_RS08265
uniprot id: Q5V3H3
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

272569:RR RS13270
gene id: 272569:RR_RS13270
uniprot id: Q5V0L7
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS16560
gene id: 272569:RR_RS16560
uniprot id: A0A4P8K5Z0
names: Similarity
messages: Belongs to the AAA ATPase family.

272569:RR RS18975
gene id: 272569:RR_RS18975
uniprot id: A0A4P8K2K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

272569:RR RS17820
gene id: 272569:RR_RS17820
uniprot id: A0A4P8JY65
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

272569:RR RS05640
gene id: 272569:RR_RS05640
uniprot id: Q5V4Z5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

272569:RR RS10815
gene id: 272569:RR_RS10815
uniprot id: Q5V203
names: Similarity
messages: Belongs to the LarC family.

272569:RR RS13745
gene id: 272569:RR_RS13745
uniprot id: A0A4P8K4I4
uniprot id: Q5V0C3
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

272569:RR RS03020
gene id: 272569:RR_RS03020
uniprot id: Q5V6H7
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS05535
gene id: 272569:RR_RS05535
uniprot id: Q5V517
names: Function
names: Similarity
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

272569:RR RS08785
gene id: 272569:RR_RS08785
uniprot id: Q5V367
names: Similarity
messages: Belongs to the UPF0047 family.

272569:RR RS13200
gene id: 272569:RR_RS13200
uniprot id: Q5V0N1
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS21030
gene id: 272569:RR_RS21030
uniprot id: Q5UW74
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS11905
gene id: 272569:RR_RS11905
uniprot id: A0A4P8JWK8
uniprot id: Q5V1D5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

272569:RR RS01345
gene id: 272569:RR_RS01345
uniprot id: Q5V7S2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

272569:RR RS13045
gene id: 272569:RR_RS13045
uniprot id: Q5V0R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

272569:RR RS11915
gene id: 272569:RR_RS11915
uniprot id: A0A4P8K3J6
uniprot id: Q5V1D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTH2 family.
messages: Cytoplasm
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

272569:RR RS08245
gene id: 272569:RR_RS08245
uniprot id: Q5V3H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Nucleus

272569:RR RS07960
gene id: 272569:RR_RS07960
uniprot id: A0A4V1ELY2
names: Similarity
messages: Belongs to the Dps family.

272569:RR RS03455
gene id: 272569:RR_RS03455
uniprot id: A0A4P8JWU1
names: Similarity
messages: Belongs to the hemerythrin family.

272569:RR RS01755
gene id: 272569:RR_RS01755
uniprot id: Q5V731
names: Similarity
messages: Belongs to the glutaredoxin family.

272569:RR RS10720
gene id: 272569:RR_RS10720
uniprot id: A0A4P8JW05
uniprot id: P49402
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

272569:RR RS20665
gene id: 272569:RR_RS20665
uniprot id: Q5UWF0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS03845
gene id: 272569:RR_RS03845
uniprot id: Q5V608
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS02560
gene id: 272569:RR_RS02560
uniprot id: Q5V6S1
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS01990
gene id: 272569:RR_RS01990
uniprot id: A0A4P8JRT0
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

272569:RR RS10375
gene id: 272569:RR_RS10375
uniprot id: Q5V291
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

272569:RR RS18500
gene id: 272569:RR_RS18500
uniprot id: Q5UXP2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS00785
gene id: 272569:RR_RS00785
uniprot id: Q5V7W8
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.

272569:RR RS00120
gene id: 272569:RR_RS00120
uniprot id: A0A4P8JQ87
uniprot id: Q5V883
names: Caution
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS13550
gene id: 272569:RR_RS13550
uniprot id: Q5V0G2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

272569:RR RS15765
gene id: 272569:RR_RS15765
uniprot id: Q5UZ87
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

272569:RR RS15920
gene id: 272569:RR_RS15920
uniprot id: Q5UZ58
names: Similarity
messages: Belongs to the threonine synthase family.

272569:RR RS17695
gene id: 272569:RR_RS17695
uniprot id: Q5UY52
names: Similarity
messages: Belongs to the HMBS family.

272569:RR RS16270
gene id: 272569:RR_RS16270
uniprot id: A0A4P8K282
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

272569:RR RS07045
gene id: 272569:RR_RS07045
uniprot id: Q5V462
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

272569:RR RS03735
gene id: 272569:RR_RS03735
uniprot id: Q5V632
names: Miscellaneous
names: Subunit
messages: Component I catalyzes the formation of anthranilate using ammonia rather than glutamine, whereas component II provides glutamine amidotransferase activity.
messages: Tetramer of two components I and two components II.

272569:RR RS14855
gene id: 272569:RR_RS14855
uniprot id: Q5UZR2
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Part of the RNA polymerase complex.

272569:RR RS02625
gene id: 272569:RR_RS02625
uniprot id: A0A4P8K0D9
names: Subcellular Location Annotation
messages: Cytoplasm

272569:RR RS11095
gene id: 272569:RR_RS11095
uniprot id: A0A4P8JYK5
uniprot id: P14121
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.
messages: Part of the 50S ribosomal subunit. Binds 5S rRNA.
messages: This is one of 5 proteins that mediate the attachment of the 5S rRNA onto the large ribosomal subunit, stabilizing the orientation of adjacent RNA domains.

272569:RR RS15170
gene id: 272569:RR_RS15170
uniprot id: Q5UZK1
names: Function
messages: Part of a potassium transport system.

272569:RR RS17950
gene id: 272569:RR_RS17950
uniprot id: Q5UY03
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

272569:RR RS19200
gene id: 272569:RR_RS19200
uniprot id: Q5UXA2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

272569:RR RS19020
gene id: 272569:RR_RS19020
uniprot id: Q5UXD8
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS12670
gene id: 272569:RR_RS12670
uniprot id: A0A4P8JWZ7
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS06915
gene id: 272569:RR_RS06915
uniprot id: A0A4P8JXB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

272569:RR RS04600
gene id: 272569:RR_RS04600
uniprot id: Q5V5K3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

272569:RR RS06205
gene id: 272569:RR_RS06205
uniprot id: Q5V4N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

272569:RR RS06535
gene id: 272569:RR_RS06535
uniprot id: A0A4P8JWH0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS19805
gene id: 272569:RR_RS19805
uniprot id: A0A4P8JZF6
uniprot id: Q5UWY4
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

272569:RR RS12580
gene id: 272569:RR_RS12580
uniprot id: A0A4V1EM69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

272569:RR RS15975
gene id: 272569:RR_RS15975
uniprot id: A0A4P8K5Q7
uniprot id: Q5UZ47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

272569:RR RS06040
gene id: 272569:RR_RS06040
uniprot id: A0A4P8K2A1
uniprot id: Q5V4R5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

272569:RR RS07345
gene id: 272569:RR_RS07345
uniprot id: Q5V404
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS18575
gene id: 272569:RR_RS18575
uniprot id: A0A4P8JYM9
uniprot id: Q5UXM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
messages: Homodimer.

272569:RR RS09175
gene id: 272569:RR_RS09175
uniprot id: A0A4P8JU58
uniprot id: Q5V2Y6
names: Similarity
messages: Belongs to the UPF0212 family.

272569:RR RS06510
gene id: 272569:RR_RS06510
uniprot id: A0A4P8K123
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS14800
gene id: 272569:RR_RS14800
uniprot id: Q5UZS3
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS09280
gene id: 272569:RR_RS09280
uniprot id: Q5V2W5
names: Similarity
messages: Belongs to the MoaB/Mog family.

272569:RR RS02255
gene id: 272569:RR_RS02255
uniprot id: Q5V7B9
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

272569:RR RS07675
gene id: 272569:RR_RS07675
uniprot id: Q5V3T8
names: Similarity
messages: Belongs to the DNA photolyase family.

272569:RR RS11655
gene id: 272569:RR_RS11655
uniprot id: A0A4P8JXI2
uniprot id: Q5V1I8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

272569:RR RS15705
gene id: 272569:RR_RS15705
uniprot id: Q5UZ99
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

272569:RR RS03530
gene id: 272569:RR_RS03530
uniprot id: Q5V672
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS16130
gene id: 272569:RR_RS16130
uniprot id: A0A4P8JXG4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

272569:RR RS06475
gene id: 272569:RR_RS06475
uniprot id: A0A4P8JWG1
uniprot id: Q5V4H7
names: Function
names: Induction
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Expressed constitutively throughout the growth phases, both in presence and absence of white light.
messages: Interacts with HtrM.
messages: Membrane
messages: Sensory rhodopsin. Associates with an unusual transducer lacking a methyl-accepting transducer domain found in all other photosensory transducers. The chromophore is all-trans-retinal in the dark.
messages: The covalent binding of retinal to the apoprotein, bacterioopsin, generates bacteriorhodopsin.

272569:RR RS04315
gene id: 272569:RR_RS04315
uniprot id: A0A4P8JZC6
uniprot id: P12733
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL18 family.
messages: Part of the 50S ribosomal subunit. Interacts weakly with proteins L4 and L15. Has been cross-linked to L4.
messages: Stabilizes the tertiary rRNA structure within the 23S rRNA domain (domain II) to which it binds.

272569:RR RS11730
gene id: 272569:RR_RS11730
uniprot id: A0A4P8JWQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

272569:RR RS07090
gene id: 272569:RR_RS07090
uniprot id: Q5V453
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

272569:RR RS12410
gene id: 272569:RR_RS12410
uniprot id: Q5V133
names: Similarity
messages: Belongs to the glutaredoxin family.

272569:RR RS19260
gene id: 272569:RR_RS19260
uniprot id: Q5UX90
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

272569:RR RS15155
gene id: 272569:RR_RS15155
uniprot id: A0A4P8K0K5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

272569:RR RS06100
gene id: 272569:RR_RS06100
uniprot id: Q5V4Q3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

272569:RR RS14810
gene id: 272569:RR_RS14810
uniprot id: Q5UZS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

272569:RR RS18655
gene id: 272569:RR_RS18655
uniprot id: Q5UXL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

272569:RR RS15780
gene id: 272569:RR_RS15780
uniprot id: A0A4P8K206
uniprot id: Q5UZ84
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

272569:RR RS06025
gene id: 272569:RR_RS06025
uniprot id: Q5V4R8
names: Similarity
messages: Belongs to the arginase family.

272569:RR RS14490
gene id: 272569:RR_RS14490
uniprot id: Q5UZY3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

272569:RR RS10985
gene id: 272569:RR_RS10985
uniprot id: A0A4P8JX82
uniprot id: Q5V1W6
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

272569:RR RS04910
gene id: 272569:RR_RS04910
uniprot id: Q5V5E0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

272569:RR RS15160
gene id: 272569:RR_RS15160
uniprot id: Q5UZK4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

272569:RR RS14495
gene id: 272569:RR_RS14495
uniprot id: A0A4P8K0A4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS16030
gene id: 272569:RR_RS16030
uniprot id: Q5UZ36
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

272569:RR RS09365
gene id: 272569:RR_RS09365
uniprot id: Q5V2U7
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS02820
gene id: 272569:RR_RS02820
uniprot id: A0A4P8JVU5
uniprot id: Q75ZQ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

272569:RR RS01665
gene id: 272569:RR_RS01665
uniprot id: Q5V6Y5
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS01355
gene id: 272569:RR_RS01355
uniprot id: Q5V7S1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

272569:RR RS13370
gene id: 272569:RR_RS13370
uniprot id: A0A4P8JYD2
uniprot id: Q5V0J7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M54 family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.
messages: Monomer.
messages: Probable zinc metalloprotease whose natural substrate is unknown.

272569:RR RS10970
gene id: 272569:RR_RS10970
uniprot id: Q5V1W9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

272569:RR RS02480
gene id: 272569:RR_RS02480
uniprot id: Q5V6T7
names: Similarity
messages: Belongs to the GbsR family.

272569:RR RS07325
gene id: 272569:RR_RS07325
uniprot id: A0A4V1ELX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
messages: Cytoplasm

272569:RR RS09610
gene id: 272569:RR_RS09610
uniprot id: A0A4P8JXX8
uniprot id: Q5V2P8
names: Caution
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS11895
gene id: 272569:RR_RS11895
uniprot id: Q5V1D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

272569:RR RS17835
gene id: 272569:RR_RS17835
uniprot id: Q5UY25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

272569:RR RS16920
gene id: 272569:RR_RS16920
uniprot id: Q5UYK5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

272569:RR RS07800
gene id: 272569:RR_RS07800
uniprot id: A0A4V1ELX9
uniprot id: Q5V3R4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

272569:RR RS06045
gene id: 272569:RR_RS06045
uniprot id: A0A4P8K138
uniprot id: Q5V4R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

272569:RR RS14825
gene id: 272569:RR_RS14825
uniprot id: A0A4P8JY76
uniprot id: Q5UZR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

272569:RR RS07890
gene id: 272569:RR_RS07890
uniprot id: A0A4P8JVT8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

272569:RR RS05350
gene id: 272569:RR_RS05350
uniprot id: A0A4P8K512
uniprot id: Q5V554
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

272569:RR RS03175
gene id: 272569:RR_RS03175
uniprot id: Q5V6E4
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

272569:RR RS12485
gene id: 272569:RR_RS12485
uniprot id: Q5V118
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

272569:RR RS06740
gene id: 272569:RR_RS06740
uniprot id: A0A4P8K155
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

272569:RR RS11325
gene id: 272569:RR_RS11325
uniprot id: Q5V1Q1
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS04870
gene id: 272569:RR_RS04870
uniprot id: Q5V5E8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

272569:RR RS13630
gene id: 272569:RR_RS13630
uniprot id: A0A4P8JXG1
uniprot id: Q5V0E6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

272569:RR RS17955
gene id: 272569:RR_RS17955
uniprot id: Q5UY02
names: Similarity
messages: Belongs to the UPF0201 family.

272569:RR RS12160
gene id: 272569:RR_RS12160
uniprot id: Q5V186
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

272569:RR RS08435
gene id: 272569:RR_RS08435
uniprot id: A0A4P8JY48
uniprot id: Q5V3D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

272569:RR RS18020
gene id: 272569:RR_RS18020
uniprot id: Q5UXY9
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

272569:RR RS17655
gene id: 272569:RR_RS17655
uniprot id: Q5UY61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

272569:RR RS19000
gene id: 272569:RR_RS19000
uniprot id: A0A4P8K707
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

272569:RR RS19480
gene id: 272569:RR_RS19480
uniprot id: A0A4P8JZ06
uniprot id: Q5UX45
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Could lack activity as the potential active site Cys residue in position 78 is replaced by an Ala.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS15485
gene id: 272569:RR_RS15485
uniprot id: A0A4P8JZE0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

272569:RR RS07095
gene id: 272569:RR_RS07095
uniprot id: A0A4P8JVF3
uniprot id: Q5V452
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

272569:RR RS11545
gene id: 272569:RR_RS11545
uniprot id: Q5V1K8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

272569:RR RS05715
gene id: 272569:RR_RS05715
uniprot id: Q5V4Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

272569:RR RS06195
gene id: 272569:RR_RS06195
uniprot id: A0A4P8JSS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

272569:RR RS20590
gene id: 272569:RR_RS20590
uniprot id: Q5UWG6
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS10830
gene id: 272569:RR_RS10830
uniprot id: A0A4P8JW23
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
messages: Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.

272569:RR RS03740
gene id: 272569:RR_RS03740
uniprot id: A0A4P8K016
uniprot id: Q5V631
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component I catalyzes the formation of anthranilate using ammonia rather than glutamine, whereas component II provides glutamine amidotransferase activity.
messages: Tetramer of two components I and two components II.

272569:RR RS07705
gene id: 272569:RR_RS07705
uniprot id: A0A4P8JTG0
uniprot id: Q5V3T2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

272569:RR RS18745
gene id: 272569:RR_RS18745
uniprot id: Q5UXJ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS05140
gene id: 272569:RR_RS05140
uniprot id: A0A4P8K4X6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

272569:RR RS12850
gene id: 272569:RR_RS12850
uniprot id: Q5V0U9
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS11250
gene id: 272569:RR_RS11250
uniprot id: Q5V1R5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

272569:RR RS14750
gene id: 272569:RR_RS14750
uniprot id: A0A4P8JY02
uniprot id: P16018
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

272569:RR RS04820
gene id: 272569:RR_RS04820
uniprot id: A0A4P8JZH3
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS00485
gene id: 272569:RR_RS00485
uniprot id: Q5V802
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

272569:RR RS04970
gene id: 272569:RR_RS04970
uniprot id: A0A4P8K0X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

272569:RR RS17815
gene id: 272569:RR_RS17815
uniprot id: A0A4P8JZK6
uniprot id: P18138
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Belongs to the ribosomal protein L31e family.
messages: Binds to the 23S rRNA. Located at the polypeptide exit tunnel on the outside of the subunit.
messages: Part of the 50S ribosomal subunit.

272569:RR RS16545
gene id: 272569:RR_RS16545
uniprot id: Q5UYT2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

272569:RR RS13925
gene id: 272569:RR_RS13925
uniprot id: Q5V088
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS07530
gene id: 272569:RR_RS07530
uniprot id: A0A4P8JUU6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

272569:RR RS19135
gene id: 272569:RR_RS19135
uniprot id: Q5UXB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

272569:RR RS13075
gene id: 272569:RR_RS13075
uniprot id: Q5V0Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

272569:RR RS11145
gene id: 272569:RR_RS11145
uniprot id: A0A4P8JYL3
uniprot id: P10972
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.
messages: Part of the 50S ribosomal subunit. Interacts weakly with protein L4.
messages: Stabilizes the tertiary rRNA structure within the 23S rRNA domain (domain I) to which it binds. Located at the polypeptide exit tunnel on the outside of the subunit.

272569:RR RS08930
gene id: 272569:RR_RS08930
uniprot id: Q5V339
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

272569:RR RS16785
gene id: 272569:RR_RS16785
uniprot id: Q5UYN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS09360
gene id: 272569:RR_RS09360
uniprot id: Q5V2U8
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS01010
gene id: 272569:RR_RS01010
uniprot id: Q5V7K2
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS19420
gene id: 272569:RR_RS19420
uniprot id: A0A4P8K0D4
uniprot id: Q5UX57
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS05595
gene id: 272569:RR_RS05595
uniprot id: Q5V504
names: Subcellular Location Annotation
messages: Cell membrane

272569:RR RS18030
gene id: 272569:RR_RS18030
uniprot id: A0A4P8K1W0
uniprot id: Q5UXY7
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

272569:RR RS03855
gene id: 272569:RR_RS03855
uniprot id: Q5V606
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

272569:RR RS11085
gene id: 272569:RR_RS11085
uniprot id: A0A4P8JYL4
uniprot id: P28542
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

272569:RR RS09460
gene id: 272569:RR_RS09460
uniprot id: Q5V2S8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

272569:RR RS11875
gene id: 272569:RR_RS11875
uniprot id: Q5V1E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

272569:RR RS14075
gene id: 272569:RR_RS14075
uniprot id: A0A4P8K042
uniprot id: Q5V059
names: Function
names: Similarity
messages: Belongs to the HARP family.
messages: RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.

272569:RR RS06945
gene id: 272569:RR_RS06945
uniprot id: A0A4P8K076
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS18055
gene id: 272569:RR_RS18055
uniprot id: A0A4P8JYD4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

272569:RR RS07905
gene id: 272569:RR_RS07905
uniprot id: Q5V3P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

272569:RR RS13315
gene id: 272569:RR_RS13315
uniprot id: Q5V0K8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

272569:RR RS15855
gene id: 272569:RR_RS15855
uniprot id: Q5UZ71
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS18000
gene id: 272569:RR_RS18000
uniprot id: Q5UXZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

272569:RR RS10000
gene id: 272569:RR_RS10000
uniprot id: Q5V2G4
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

272569:RR RS01090
gene id: 272569:RR_RS01090
uniprot id: Q5V7L9
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS17600
gene id: 272569:RR_RS17600
uniprot id: Q5UY72
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

272569:RR RS02390
gene id: 272569:RR_RS02390
uniprot id: Q5V6V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS05825
gene id: 272569:RR_RS05825
uniprot id: Q5V4V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

272569:RR RS07475
gene id: 272569:RR_RS07475
uniprot id: Q5V3X7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

272569:RR RS10420
gene id: 272569:RR_RS10420
uniprot id: A0A4P8JW45
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS13055
gene id: 272569:RR_RS13055
uniprot id: Q5V0R0
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

272569:RR RS19270
gene id: 272569:RR_RS19270
uniprot id: A0A4P8K0B0
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS11640
gene id: 272569:RR_RS11640
uniprot id: Q5V1J0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

272569:RR RS11130
gene id: 272569:RR_RS11130
uniprot id: A0A4P8JUY8
uniprot id: P26816
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

272569:RR RS04775
gene id: 272569:RR_RS04775
uniprot id: Q5V5G7
names: Similarity
messages: Belongs to the glutamate synthase family.

272569:RR RS13705
gene id: 272569:RR_RS13705
uniprot id: Q5V0D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NAD to NADH.
messages: Homotetramer.

272569:RR RS12950
gene id: 272569:RR_RS12950
uniprot id: Q5V0T1
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS16535
gene id: 272569:RR_RS16535
uniprot id: Q5UYT5
names: Similarity
messages: Belongs to the thioesterase PaaI family.

272569:RR RS11170
gene id: 272569:RR_RS11170
uniprot id: A0A4V1EM42
uniprot id: P20281
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

272569:RR RS19425
gene id: 272569:RR_RS19425
uniprot id: A0A4P8JYZ7
uniprot id: Q5UX56
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

272569:RR RS04835
gene id: 272569:RR_RS04835
uniprot id: Q5V5F5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

272569:RR RS09950
gene id: 272569:RR_RS09950
uniprot id: A0A4P8K175
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

272569:RR RS14780
gene id: 272569:RR_RS14780
uniprot id: A0A4P8JWS1
uniprot id: Q5UZS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

272569:RR RS20215
gene id: 272569:RR_RS20215
uniprot id: Q5UWP5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS16340
gene id: 272569:RR_RS16340
uniprot id: Q5UYX3
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

272569:RR RS03295
gene id: 272569:RR_RS03295
uniprot id: Q5V6B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS14145
gene id: 272569:RR_RS14145
uniprot id: Q5V048
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS06070
gene id: 272569:RR_RS06070
uniprot id: Q5V4Q9
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS15020
gene id: 272569:RR_RS15020
uniprot id: Q5UZN1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS18280
gene id: 272569:RR_RS18280
uniprot id: A0A4P8K205
uniprot id: Q5UXT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

272569:RR RS13900
gene id: 272569:RR_RS13900
uniprot id: Q5V093
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS12495
gene id: 272569:RR_RS12495
uniprot id: Q5V116
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively.
messages: Belongs to the peptidase S16 family. Archaeal LonB subfamily.
messages: Cell membrane
messages: Homohexamer. Organized in a ring with a central cavity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

272569:RR RS11090
gene id: 272569:RR_RS11090
uniprot id: A0A4P8JZA1
uniprot id: P12737
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.
messages: Part of the 50S ribosomal subunit. Interacts weakly with proteins L18e and L32e.

272569:RR RS13080
gene id: 272569:RR_RS13080
uniprot id: Q5V0Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

272569:RR RS18095
gene id: 272569:RR_RS18095
uniprot id: A0A4P8K242
uniprot id: Q5UXX3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS15760
gene id: 272569:RR_RS15760
uniprot id: A0A4V1EMD0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS15505
gene id: 272569:RR_RS15505
uniprot id: A0A4P8K5I2
uniprot id: Q5UZD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

272569:RR RS08840
gene id: 272569:RR_RS08840
uniprot id: A0A4P8JU18
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

272569:RR RS03700
gene id: 272569:RR_RS03700
uniprot id: Q5V639
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

272569:RR RS06440
gene id: 272569:RR_RS06440
uniprot id: A0A4P8JV50
uniprot id: Q5V4I4
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS17710
gene id: 272569:RR_RS17710
uniprot id: Q5UY49
names: Similarity
messages: Belongs to the PspA/IM30 family.

272569:RR RS14355
gene id: 272569:RR_RS14355
uniprot id: Q5V011
names: Similarity
messages: Belongs to the MCM family.

272569:RR RS09060
gene id: 272569:RR_RS09060
uniprot id: A0A4P8JVK1
uniprot id: Q5V311
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS08915
gene id: 272569:RR_RS08915
uniprot id: Q5V342
names: Similarity
messages: Belongs to the UPF0284 family.

272569:RR RS16720
gene id: 272569:RR_RS16720
uniprot id: A0A4V1EME8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

272569:RR RS15030
gene id: 272569:RR_RS15030
uniprot id: Q5UZM9
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS13000
gene id: 272569:RR_RS13000
uniprot id: Q5V0S1
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

272569:RR RS04410
gene id: 272569:RR_RS04410
uniprot id: A0A4P8K0F9
uniprot id: Q5V5N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

272569:RR RS08945
gene id: 272569:RR_RS08945
uniprot id: Q5V336
names: Similarity
messages: Belongs to the GARS family.

272569:RR RS08040
gene id: 272569:RR_RS08040
uniprot id: Q5V3L7
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS16840
gene id: 272569:RR_RS16840
uniprot id: Q5UYM1
names: Biotechnology
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PHA/PHB synthase family.
messages: Heterodimer with PhaC.
messages: Involved in the production of polyhydroxyalkonic acids (PHAs), which are water-insoluble biopolymers used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. PHAs are composed primarily of 3-hydroxybutyric acid (3HB) and 3-hydroxyvaleric acid (3HV). Required for the production of poly-beta-hydroxybutyrate (PHB) and poly(beta-hydroxybutyrate-co-beta-hydroxyvalerate) (PHBV).
messages: PHB and PHBV are desirable bioplastic due to their biodegradability, biocompatibility, and mechanical properties. However, PHBV has better mechanical properties than PHB.

272569:RR RS14990
gene id: 272569:RR_RS14990
uniprot id: Q5UZN7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

272569:RR RS19905
gene id: 272569:RR_RS19905
uniprot id: Q5UWW0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

272569:RR RS15330
gene id: 272569:RR_RS15330
uniprot id: A0A4P8K0S0
uniprot id: Q5UZH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

272569:RR RS06010
gene id: 272569:RR_RS06010
uniprot id: Q5V4S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADH dehydrogenase family.
messages: Cytoplasm

272569:RR RS18770
gene id: 272569:RR_RS18770
uniprot id: Q5UXJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

272569:RR RS02435
gene id: 272569:RR_RS02435
uniprot id: A0A4P8JVM2
uniprot id: Q5V6U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

272569:RR RS06090
gene id: 272569:RR_RS06090
uniprot id: A0A4P8JSR2
uniprot id: Q5V4Q5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.

272569:RR RS19155
gene id: 272569:RR_RS19155
uniprot id: Q5UXB1
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

272569:RR RS12790
gene id: 272569:RR_RS12790
uniprot id: Q5V0W1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

272569:RR RS07215
gene id: 272569:RR_RS07215
uniprot id: Q5V428
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS15465
gene id: 272569:RR_RS15465
uniprot id: A0A4P8JX34
uniprot id: Q5UZE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

272569:RR RS14860
gene id: 272569:RR_RS14860
uniprot id: Q5UZR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

272569:RR RS18865
gene id: 272569:RR_RS18865
uniprot id: A0A4P8JYP5
uniprot id: Q5UXH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

272569:RR RS17505
gene id: 272569:RR_RS17505
uniprot id: Q5UY91
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

272569:RR RS06095
gene id: 272569:RR_RS06095
uniprot id: A0A4P8JW96
uniprot id: Q5V4Q4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

272569:RR RS09355
gene id: 272569:RR_RS09355
uniprot id: Q5V2U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

272569:RR RS05570
gene id: 272569:RR_RS05570
uniprot id: Q5V510
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

272569:RR RS12845
gene id: 272569:RR_RS12845
uniprot id: Q5V0V0
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS14425
gene id: 272569:RR_RS14425
uniprot id: A0A4P8K4U3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

272569:RR RS16860
gene id: 272569:RR_RS16860
uniprot id: A0A4P8K2I5
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

272569:RR RS12380
gene id: 272569:RR_RS12380
uniprot id: Q5V139
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

272569:RR RS05465
gene id: 272569:RR_RS05465
uniprot id: Q5V532
names: Subcellular Location Annotation
messages: Cell membrane

272569:RR RS20675
gene id: 272569:RR_RS20675
uniprot id: Q5UWE8
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS02335
gene id: 272569:RR_RS02335
uniprot id: A0A4P8JW82
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

272569:RR RS16780
gene id: 272569:RR_RS16780
uniprot id: Q5UYN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS02550
gene id: 272569:RR_RS02550
uniprot id: Q5V6S3
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

272569:RR RS15350
gene id: 272569:RR_RS15350
uniprot id: Q5UZG8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS08920
gene id: 272569:RR_RS08920
uniprot id: A0A4P8JYC6
uniprot id: Q5V341
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

272569:RR RS11155
gene id: 272569:RR_RS11155
uniprot id: A0A4P8JW76
uniprot id: P12741
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

272569:RR RS12370
gene id: 272569:RR_RS12370
uniprot id: Q5V141
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

272569:RR RS15530
gene id: 272569:RR_RS15530
uniprot id: A0A4P8K1V8
uniprot id: Q5UZD3
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

272569:RR RS18860
gene id: 272569:RR_RS18860
uniprot id: A0A4P8K032
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

272569:RR RS09985
gene id: 272569:RR_RS09985
uniprot id: Q5V2G7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

272569:RR RS10210
gene id: 272569:RR_RS10210
uniprot id: A0A4P8K057
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

272569:RR RS20580
gene id: 272569:RR_RS20580
uniprot id: Q5UWG8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS17700
gene id: 272569:RR_RS17700
uniprot id: Q5UY51
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

272569:RR RS15275
gene id: 272569:RR_RS15275
uniprot id: A0A4P8K1R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

272569:RR RS04340
gene id: 272569:RR_RS04340
uniprot id: A0A4P8K2V3
uniprot id: P29201
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

272569:RR RS16725
gene id: 272569:RR_RS16725
uniprot id: Q5UYP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

272569:RR RS09210
gene id: 272569:RR_RS09210
uniprot id: Q5V2X9
names: Similarity
messages: Belongs to the SDO1/SBDS family.

272569:RR RS05190
gene id: 272569:RR_RS05190
uniprot id: Q5V586
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

272569:RR RS15105
gene id: 272569:RR_RS15105
uniprot id: Q5UZL4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

272569:RR RS14155
gene id: 272569:RR_RS14155
uniprot id: Q5V046
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS17355
gene id: 272569:RR_RS17355
uniprot id: Q5UYC4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

272569:RR RS02980
gene id: 272569:RR_RS02980
uniprot id: Q5V6I5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS18640
gene id: 272569:RR_RS18640
uniprot id: A0A4V1EMI4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS18305
gene id: 272569:RR_RS18305
uniprot id: Q5UXS9
names: Function
names: Subunit
messages: Interacts with chemotaxis (Che) proteins as well as flagella accessory (Fla) proteins.
messages: Involved in taxis signal transduction.

272569:RR RS11335
gene id: 272569:RR_RS11335
uniprot id: Q5V1P9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

272569:RR RS19620
gene id: 272569:RR_RS19620
uniprot id: A0A4V1EMQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

272569:RR RS19405
gene id: 272569:RR_RS19405
uniprot id: Q5UX61
names: Similarity
messages: Belongs to the PspA/IM30 family.

272569:RR RS03405
gene id: 272569:RR_RS03405
uniprot id: Q5V697
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS16100
gene id: 272569:RR_RS16100
uniprot id: Q5UZ20
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

272569:RR RS17495
gene id: 272569:RR_RS17495
uniprot id: Q5UY95
names: Function
names: Induction
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Expression is induced during growth on D-xylose.
messages: Homotretramer.
messages: NADP-dependent D-xylose dehydrogenase involved in the degradation of D-xylose, a major component of hemicelluloses such as xylan. In addition to D-xylose, oxidizes D-ribose at similar kinetic constants, whereas D-glucose is oxidized with about 70-fold lower catalytic efficiency.

272569:RR RS19055
gene id: 272569:RR_RS19055
uniprot id: A0A4P8K716
uniprot id: Q5UXD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS05515
gene id: 272569:RR_RS05515
uniprot id: A0A4P8K218
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

272569:RR RS07070
gene id: 272569:RR_RS07070
uniprot id: Q5V457
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

272569:RR RS06980
gene id: 272569:RR_RS06980
uniprot id: Q5V475
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS18595
gene id: 272569:RR_RS18595
uniprot id: A0A4P8JYK2
uniprot id: Q5UXM3
names: Similarity
messages: Belongs to the thymidylate kinase family.

272569:RR RS17890
gene id: 272569:RR_RS17890
uniprot id: Q5UY15
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS12360
gene id: 272569:RR_RS12360
uniprot id: A0A4P8JWU3
uniprot id: Q5V143
names: Function
names: Similarity
messages: Belongs to the archaeal-type DHQ synthase family.
messages: Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.

272569:RR RS19925
gene id: 272569:RR_RS19925
uniprot id: Q5UWV5
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS20630
gene id: 272569:RR_RS20630
uniprot id: A0A4P8JTA6
names: Similarity
messages: Belongs to the thioesterase PaaI family.

272569:RR RS10620
gene id: 272569:RR_RS10620
uniprot id: Q5V242
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADH dehydrogenase family.
messages: Cytoplasm

272569:RR RS05000
gene id: 272569:RR_RS05000
uniprot id: Q5V5C5
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

272569:RR RS18275
gene id: 272569:RR_RS18275
uniprot id: Q5UXT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

272569:RR RS15115
gene id: 272569:RR_RS15115
uniprot id: Q5UZL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

272569:RR RS15130
gene id: 272569:RR_RS15130
uniprot id: A0A4P8JX05
uniprot id: P19953
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

272569:RR RS08570
gene id: 272569:RR_RS08570
uniprot id: Q5V3A9
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS02810
gene id: 272569:RR_RS02810
uniprot id: Q5V6M0
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS17530
gene id: 272569:RR_RS17530
uniprot id: A0A4P8JZ91
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

272569:RR RS14850
gene id: 272569:RR_RS14850
uniprot id: Q5UZR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

272569:RR RS16125
gene id: 272569:RR_RS16125
uniprot id: Q5UZ15
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS18870
gene id: 272569:RR_RS18870
uniprot id: Q5UXG9
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS17965
gene id: 272569:RR_RS17965
uniprot id: Q5UY00
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

272569:RR RS09275
gene id: 272569:RR_RS09275
uniprot id: Q5V2W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

272569:RR RS18715
gene id: 272569:RR_RS18715
uniprot id: Q5UXK0
names: Similarity
messages: Belongs to the cytochrome P450 family.

272569:RR RS09375
gene id: 272569:RR_RS09375
uniprot id: Q5V2U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

272569:RR RS14505
gene id: 272569:RR_RS14505
uniprot id: Q5UZY0
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

272569:RR RS12885
gene id: 272569:RR_RS12885
uniprot id: Q5V0U3
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS08105
gene id: 272569:RR_RS08105
uniprot id: Q5V3K4
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

272569:RR RS19740
gene id: 272569:RR_RS19740
uniprot id: A0A4P8K1C7
names: Subcellular Location Annotation
messages: Cytoplasm

272569:RR RS03485
gene id: 272569:RR_RS03485
uniprot id: Q5V681
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

272569:RR RS10430
gene id: 272569:RR_RS10430
uniprot id: Q5V280
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

272569:RR RS15060
gene id: 272569:RR_RS15060
uniprot id: A0A4P8JZ66
uniprot id: Q5UZM2
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

272569:RR RS17970
gene id: 272569:RR_RS17970
uniprot id: Q5UXZ9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

272569:RR RS14060
gene id: 272569:RR_RS14060
uniprot id: A0A4V1EM97
uniprot id: Q5V061
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

272569:RR RS04110
gene id: 272569:RR_RS04110
uniprot id: Q5V5U9
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

272569:RR RS10535
gene id: 272569:RR_RS10535
uniprot id: Q5V258
names: Similarity
messages: Belongs to the pirin family.

272569:RR RS13530
gene id: 272569:RR_RS13530
uniprot id: A0A4P8JXE0
uniprot id: Q5V0G6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

272569:RR RS17605
gene id: 272569:RR_RS17605
uniprot id: A0A4P8JY30
uniprot id: Q5UY71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

272569:RR RS12140
gene id: 272569:RR_RS12140
uniprot id: Q5V190
names: Similarity
messages: Belongs to the DtxR/MntR family.

272569:RR RS08150
gene id: 272569:RR_RS08150
uniprot id: A0A4P8JTQ6
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

272569:RR RS05385
gene id: 272569:RR_RS05385
uniprot id: A0A4P8K133
uniprot id: Q5V547
names: Similarity
messages: Belongs to the UPF0173 family.

272569:RR RS09730
gene id: 272569:RR_RS09730
uniprot id: A0A4P8JVK7
uniprot id: Q5V2M3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

272569:RR RS04010
gene id: 272569:RR_RS04010
uniprot id: Q5V5X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

272569:RR RS11470
gene id: 272569:RR_RS11470
uniprot id: A0A4P8JV36
uniprot id: Q5V1M2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

272569:RR RS12440
gene id: 272569:RR_RS12440
uniprot id: Q5V127
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Brp/Blh beta-carotene diooxygenase family.
messages: Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS03755
gene id: 272569:RR_RS03755
uniprot id: Q5V628
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

272569:RR RS05310
gene id: 272569:RR_RS05310
uniprot id: Q5V561
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

272569:RR RS17825
gene id: 272569:RR_RS17825
uniprot id: A0A4P8K1S4
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

272569:RR RS09990
gene id: 272569:RR_RS09990
uniprot id: A0A4P8JY36
uniprot id: Q5V2G6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

272569:RR RS18875
gene id: 272569:RR_RS18875
uniprot id: A0A4P8K3X8
uniprot id: Q5UXG8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

272569:RR RS07940
gene id: 272569:RR_RS07940
uniprot id: A0A4P8JVU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS16695
gene id: 272569:RR_RS16695
uniprot id: A0A4P8K3V7
uniprot id: Q9P9H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.

272569:RR RS17175
gene id: 272569:RR_RS17175
uniprot id: A0A4P8K1G5
uniprot id: Q5UYF3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

272569:RR RS10360
gene id: 272569:RR_RS10360
uniprot id: Q5V294
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS11520
gene id: 272569:RR_RS11520
uniprot id: A0A4P8JWL0
uniprot id: Q5V1L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

272569:RR RS09015
gene id: 272569:RR_RS09015
uniprot id: Q5V321
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

272569:RR RS03850
gene id: 272569:RR_RS03850
uniprot id: A0A4V1ELR9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

272569:RR RS09000
gene id: 272569:RR_RS09000
uniprot id: A0A4P8K2A9
uniprot id: Q5V325
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS16460
gene id: 272569:RR_RS16460
uniprot id: Q5UYV1
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

272569:RR RS05365
gene id: 272569:RR_RS05365
uniprot id: Q5V551
names: Similarity
messages: Belongs to the peptidase S1C family.

272569:RR RS05995
gene id: 272569:RR_RS05995
uniprot id: Q5V4S4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

272569:RR RS04220
gene id: 272569:RR_RS04220
uniprot id: A0A4P8K0L0
uniprot id: Q5V5S6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

272569:RR RS16080
gene id: 272569:RR_RS16080
uniprot id: A0A4P8K5S3
uniprot id: Q5UZ24
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

272569:RR RS07885
gene id: 272569:RR_RS07885
uniprot id: Q5V3P9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

272569:RR RS16010
gene id: 272569:RR_RS16010
uniprot id: A0A4P8K132
uniprot id: Q5UZ40
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.
messages: This protein undergoes a protein self splicing that involves a post-translational excision of the intervening region (intein) followed by peptide ligation.

272569:RR RS10170
gene id: 272569:RR_RS10170
uniprot id: A0A4P8JVS1
uniprot id: Q5V2C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

272569:RR RS02835
gene id: 272569:RR_RS02835
uniprot id: A0A4P8JUK7
uniprot id: Q75ZQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

272569:RR RS12575
gene id: 272569:RR_RS12575
uniprot id: A0A4P8K3V3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

272569:RR RS07935
gene id: 272569:RR_RS07935
uniprot id: Q5V3N9
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

272569:RR RS08685
gene id: 272569:RR_RS08685
uniprot id: Q5V387
names: Similarity
messages: Belongs to the UPF0175 family.

272569:RR RS06035
gene id: 272569:RR_RS06035
uniprot id: Q5V4R6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

272569:RR RS04270
gene id: 272569:RR_RS04270
uniprot id: A0A4P8K0L8
uniprot id: Q5V5R5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

272569:RR RS05090
gene id: 272569:RR_RS05090
uniprot id: Q5V5A6
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

272569:RR RS16935
gene id: 272569:RR_RS16935
uniprot id: A0A4V1EMF2
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

272569:RR RS13990
gene id: 272569:RR_RS13990
uniprot id: A0A4P8JXN2
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

272569:RR RS09315
gene id: 272569:RR_RS09315
uniprot id: F2Z632
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS11805
gene id: 272569:RR_RS11805
uniprot id: A0A4P8JWI6
uniprot id: Q5V1F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

272569:RR RS05980
gene id: 272569:RR_RS05980
uniprot id: A0A4P8K5A9
uniprot id: Q5V4S7
names: Similarity
messages: Belongs to the UPF0212 family.

272569:RR RS13005
gene id: 272569:RR_RS13005
uniprot id: A0A4P8K1A4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

272569:RR RS13625
gene id: 272569:RR_RS13625
uniprot id: Q5V0E7
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

272569:RR RS15150
gene id: 272569:RR_RS15150
uniprot id: Q5UZK6
names: Similarity
messages: Belongs to the HAM1 NTPase family.

272569:RR RS18010
gene id: 272569:RR_RS18010
uniprot id: A0A4P8K6K6
uniprot id: Q5UXZ1
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

272569:RR RS07740
gene id: 272569:RR_RS07740
uniprot id: Q5V3S6
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

272569:RR RS18140
gene id: 272569:RR_RS18140
uniprot id: A0A4P8K363
uniprot id: Q5UXW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

272569:RR RS09035
gene id: 272569:RR_RS09035
uniprot id: Q5V316
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Homodimer.

272569:RR RS21080
gene id: 272569:RR_RS21080
uniprot id: A0A4P8JZE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS04635
gene id: 272569:RR_RS04635
uniprot id: Q5V5J6
names: Similarity
messages: Belongs to the TPP enzyme family.

272569:RR RS07840
gene id: 272569:RR_RS07840
uniprot id: A0A4P8JTJ8
uniprot id: Q5V3Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

272569:RR RS04100
gene id: 272569:RR_RS04100
uniprot id: Q5V5V1
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

272569:RR RS01620
gene id: 272569:RR_RS01620
uniprot id: Q5V713
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS12815
gene id: 272569:RR_RS12815
uniprot id: A0A4P8K063
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

272569:RR RS10590
gene id: 272569:RR_RS10590
uniprot id: Q5V248
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

272569:RR RS07925
gene id: 272569:RR_RS07925
uniprot id: A0A4P8JX55
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS07745
gene id: 272569:RR_RS07745
uniprot id: Q5V3S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

272569:RR RS13310
gene id: 272569:RR_RS13310
uniprot id: Q5V0K9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

272569:RR RS10545
gene id: 272569:RR_RS10545
uniprot id: Q5V256
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS10270
gene id: 272569:RR_RS10270
uniprot id: A0A4P8JYX6
uniprot id: P14122
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which 3 L12 dimers bind in a sequential fashion (Probable).
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

272569:RR RS20930
gene id: 272569:RR_RS20930
uniprot id: Q5UW95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

272569:RR RS04590
gene id: 272569:RR_RS04590
uniprot id: A0A4P8JZG9
uniprot id: Q5V5K5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

272569:RR RS15890
gene id: 272569:RR_RS15890
uniprot id: Q5UZ64
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

272569:RR RS07795
gene id: 272569:RR_RS07795
uniprot id: Q5V3R5
names: Similarity
messages: Belongs to the glutaredoxin family.

272569:RR RS11350
gene id: 272569:RR_RS11350
uniprot id: A0A4P8JWI5
uniprot id: Q5V1P6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

272569:RR RS03920
gene id: 272569:RR_RS03920
uniprot id: Q5V5Z1
names: Similarity
messages: Belongs to the GcvT family.

272569:RR RS08855
gene id: 272569:RR_RS08855
uniprot id: Q5V353
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

272569:RR RS18325
gene id: 272569:RR_RS18325
uniprot id: A0A4P8JZU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

272569:RR RS10765
gene id: 272569:RR_RS10765
uniprot id: A0A4P8JYG1
uniprot id: Q5V212
names: Similarity
messages: Belongs to the TrpF family.

272569:RR RS09665
gene id: 272569:RR_RS09665
uniprot id: Q5V2N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

272569:RR RS12535
gene id: 272569:RR_RS12535
uniprot id: Q5V108
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

272569:RR RS11235
gene id: 272569:RR_RS11235
uniprot id: Q5V1R8
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

272569:RR RS13715
gene id: 272569:RR_RS13715
uniprot id: Q5V0C9
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS19385
gene id: 272569:RR_RS19385
uniprot id: A0A4P8K479
uniprot id: Q5UX65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

272569:RR RS04390
gene id: 272569:RR_RS04390
uniprot id: A0A4P8K2W2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

272569:RR RS07330
gene id: 272569:RR_RS07330
uniprot id: Q5V407
names: Function
messages: Part of a potassium transport system.

272569:RR RS11180
gene id: 272569:RR_RS11180
uniprot id: A0A4P8JUZ8
uniprot id: P20284
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

272569:RR RS03960
gene id: 272569:RR_RS03960
uniprot id: A0A4P8JTJ3
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

272569:RR RS17020
gene id: 272569:RR_RS17020
uniprot id: A0A4P8K039
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

272569:RR RS12170
gene id: 272569:RR_RS12170
uniprot id: A0A4P8JVL1
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

272569:RR RS09995
gene id: 272569:RR_RS09995
uniprot id: Q5V2G5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

272569:RR RS15850
gene id: 272569:RR_RS15850
uniprot id: A0A4P8K413
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS06005
gene id: 272569:RR_RS06005
uniprot id: Q5V4S2
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

272569:RR RS19010
gene id: 272569:RR_RS19010
uniprot id: A0A4P8K061
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS18205
gene id: 272569:RR_RS18205
uniprot id: Q5UXV0
names: Similarity
messages: Belongs to the PdaD family.

272569:RR RS02845
gene id: 272569:RR_RS02845
uniprot id: F2Z603
names: Subcellular Location Annotation
messages: Cytoplasm

272569:RR RS14600
gene id: 272569:RR_RS14600
uniprot id: A0A4P8K0C4
uniprot id: Q5UZW0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

272569:RR RS17085
gene id: 272569:RR_RS17085
uniprot id: Q5UYH0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

272569:RR RS18350
gene id: 272569:RR_RS18350
uniprot id: Q5UXS0
names: Function
names: Subunit
messages: Interacts with chemotaxis (Che) proteins as well as flagella accessory (Fla) proteins.
messages: Involved in taxis signal transduction.

272569:RR RS09265
gene id: 272569:RR_RS09265
uniprot id: Q5V2W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS05730
gene id: 272569:RR_RS05730
uniprot id: Q5V4X7
names: Similarity
messages: Belongs to the arginase family.

272569:RR RS18355
gene id: 272569:RR_RS18355
uniprot id: Q5UXR9
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

272569:RR RS11910
gene id: 272569:RR_RS11910
uniprot id: A0A4P8JVG7
uniprot id: Q5V1D4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

272569:RR RS02645
gene id: 272569:RR_RS02645
uniprot id: Q5V6Q3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

272569:RR RS16630
gene id: 272569:RR_RS16630
uniprot id: A0A4P8K1E7
uniprot id: Q5UYR5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

272569:RR RS18890
gene id: 272569:RR_RS18890
uniprot id: A0A4P8JZW3
uniprot id: Q5UXG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

272569:RR RS06850
gene id: 272569:RR_RS06850
uniprot id: Q5V4A2
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS01585
gene id: 272569:RR_RS01585
uniprot id: A0A4P8JQB9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS06370
gene id: 272569:RR_RS06370
uniprot id: A0A4P8JWE2
uniprot id: Q5V4J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

272569:RR RS17550
gene id: 272569:RR_RS17550
uniprot id: Q5UY82
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS07775
gene id: 272569:RR_RS07775
uniprot id: A0A4P8JX02
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

272569:RR RS06190
gene id: 272569:RR_RS06190
uniprot id: Q5V4N3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

272569:RR RS21060
gene id: 272569:RR_RS21060
uniprot id: Q5UW68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS03400
gene id: 272569:RR_RS03400
uniprot id: Q5V698
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS19015
gene id: 272569:RR_RS19015
uniprot id: Q5UXD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

272569:RR RS14890
gene id: 272569:RR_RS14890
uniprot id: A0A4P8JWT9
uniprot id: Q5UZQ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofE family.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
messages: Homodimer.
messages: Monovalent cation. The ion could be potassium.

272569:RR RS05340
gene id: 272569:RR_RS05340
uniprot id: Q5V555
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS20610
gene id: 272569:RR_RS20610
uniprot id: Q5UWG1
names: Similarity
messages: Belongs to the TPP enzyme family.

272569:RR RS16095
gene id: 272569:RR_RS16095
uniprot id: A0A4P8JYS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

272569:RR RS06790
gene id: 272569:RR_RS06790
uniprot id: Q5V4B4
names: Similarity
messages: Belongs to the peptidase S49 family.

272569:RR RS19225
gene id: 272569:RR_RS19225
uniprot id: Q5UX97
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS10770
gene id: 272569:RR_RS10770
uniprot id: A0A4P8JX48
uniprot id: Q5V211
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS06815
gene id: 272569:RR_RS06815
uniprot id: Q5V4A9
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

272569:RR RS07315
gene id: 272569:RR_RS07315
uniprot id: A0A4P8JTB1
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

272569:RR RS10440
gene id: 272569:RR_RS10440
uniprot id: Q5V278
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

272569:RR RS09435
gene id: 272569:RR_RS09435
uniprot id: A0A4P8JYK4
uniprot id: Q5V2T3
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

272569:RR RS14960
gene id: 272569:RR_RS14960
uniprot id: Q5UZP4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

272569:RR RS11950
gene id: 272569:RR_RS11950
uniprot id: A0A4P8JXN1
uniprot id: Q3V7Z9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: During the catalytic reaction, a sulfide is transferred from Cys-169 to a reaction intermediate, generating a dehydroalanine residue.
messages: Homooctamer; tetramer of dimers.
messages: Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS07810
gene id: 272569:RR_RS07810
uniprot id: A0A4P8JTI2
uniprot id: Q5V3R2
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).

272569:RR RS05070
gene id: 272569:RR_RS05070
uniprot id: Q5V5B0
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

272569:RR RS09190
gene id: 272569:RR_RS09190
uniprot id: Q5V2Y3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS08300
gene id: 272569:RR_RS08300
uniprot id: A0A4P8JUY4
uniprot id: Q5V3G6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

272569:RR RS15040
gene id: 272569:RR_RS15040
uniprot id: Q5UZM7
names: Similarity
messages: Belongs to the proline racemase family.

272569:RR RS17855
gene id: 272569:RR_RS17855
uniprot id: Q5UY22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

272569:RR RS03800
gene id: 272569:RR_RS03800
uniprot id: Q5V619
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS05400
gene id: 272569:RR_RS05400
uniprot id: A0A4P8K517
uniprot id: Q5V545
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS10275
gene id: 272569:RR_RS10275
uniprot id: A0A4P8JY79
uniprot id: P12738
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

272569:RR RS21065
gene id: 272569:RR_RS21065
uniprot id: Q5UW67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS13225
gene id: 272569:RR_RS13225
uniprot id: Q5V0M6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS03565
gene id: 272569:RR_RS03565
uniprot id: Q5V665
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

272569:RR RS15960
gene id: 272569:RR_RS15960
uniprot id: A0A4P8JZL8
uniprot id: Q5UZ50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS16660
gene id: 272569:RR_RS16660
uniprot id: A0A4V1EME7
uniprot id: Q5UYQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

272569:RR RS08695
gene id: 272569:RR_RS08695
uniprot id: Q5V385
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

272569:RR RS15885
gene id: 272569:RR_RS15885
uniprot id: A0A4P8JYN4
uniprot id: Q5UZ65
names: Function
names: Similarity
messages: Belongs to the archaeal IMP cyclohydrolase family.
messages: Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.

272569:RR RS18125
gene id: 272569:RR_RS18125
uniprot id: A0A4P8JZQ8
uniprot id: Q5UXW7
names: Similarity
messages: Belongs to the PDCD5 family.

272569:RR RS08170
gene id: 272569:RR_RS08170
uniprot id: A0A4P8JTP2
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS12015
gene id: 272569:RR_RS12015
uniprot id: A0A4P8K3L2
uniprot id: Q5V1B4
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family. MfnA subfamily.
messages: Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

272569:RR RS10450
gene id: 272569:RR_RS10450
uniprot id: Q5V276
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS10540
gene id: 272569:RR_RS10540
uniprot id: A0A4P8JZ19
names: Subcellular Location Annotation
messages: Cytoplasm

272569:RR RS18690
gene id: 272569:RR_RS18690
uniprot id: Q5UXK5
names: Similarity
messages: Belongs to the Ahb/Nir family.

272569:RR RS15240
gene id: 272569:RR_RS15240
uniprot id: Q5UZI9
names: Similarity
messages: Belongs to the citrate synthase family.

272569:RR RS09325
gene id: 272569:RR_RS09325
uniprot id: F2Z6I3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

272569:RR RS02565
gene id: 272569:RR_RS02565
uniprot id: A0A4P8JS71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

272569:RR RS11970
gene id: 272569:RR_RS11970
uniprot id: Q5V1C3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS08780
gene id: 272569:RR_RS08780
uniprot id: Q5V368
names: Similarity
messages: Belongs to the cytochrome P450 family.

272569:RR RS12450
gene id: 272569:RR_RS12450
uniprot id: A0A4P8JZZ4
uniprot id: Q5V125
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: May catalyze a purine salvage reaction, the substrate is unknown.

272569:RR RS12775
gene id: 272569:RR_RS12775
uniprot id: Q5V0W4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

272569:RR RS14965
gene id: 272569:RR_RS14965
uniprot id: Q5UZP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

272569:RR RS09765
gene id: 272569:RR_RS09765
uniprot id: Q5V2L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADH dehydrogenase family.
messages: Cytoplasm

272569:RR RS06990
gene id: 272569:RR_RS06990
uniprot id: Q5V473
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

272569:RR RS10695
gene id: 272569:RR_RS10695
uniprot id: A0A4P8JYF9
uniprot id: Q5V225
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

272569:RR RS13815
gene id: 272569:RR_RS13815
uniprot id: Q5V0A9
names: Function
names: Subunit
messages: Interacts with chemotaxis (Che) proteins as well as flagella accessory (Fla) proteins.
messages: Involved in taxis signal transduction.

272569:RR RS18515
gene id: 272569:RR_RS18515
uniprot id: A0A4P8K0T7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

272569:RR RS08060
gene id: 272569:RR_RS08060
uniprot id: Q5V3L3
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

272569:RR RS05475
gene id: 272569:RR_RS05475
uniprot id: A0A4P8JZW6
names: Similarity
messages: Belongs to the peptidase M24B family.

272569:RR RS02250
gene id: 272569:RR_RS02250
uniprot id: Q5V7C0
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

272569:RR RS11220
gene id: 272569:RR_RS11220
uniprot id: Q5V1S1
names: Similarity
messages: Belongs to the UPF0045 family.

272569:RR RS09690
gene id: 272569:RR_RS09690
uniprot id: A0A4P8JVU3
uniprot id: Q5V2N1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

272569:RR RS11430
gene id: 272569:RR_RS11430
uniprot id: A0A4P8JXE9
uniprot id: Q5V1N0
names: Function
names: Induction
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Expressed constitutively throughout the growth phases, both in presence and absence of white light.
messages: Light-driven chloride pump.
messages: Membrane
messages: The covalent binding of retinal to the apoprotein, bacterioopsin, generates bacteriorhodopsin.

272569:RR RS11490
gene id: 272569:RR_RS11490
uniprot id: Q5V1L8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

272569:RR RS19230
gene id: 272569:RR_RS19230
uniprot id: Q5UX96
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

272569:RR RS18110
gene id: 272569:RR_RS18110
uniprot id: Q5UXX0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

272569:RR RS11830
gene id: 272569:RR_RS11830
uniprot id: Q5V1F2
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS11150
gene id: 272569:RR_RS11150
uniprot id: A0A4P8JXB0
uniprot id: P22450
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Forms part of two intersubunit bridges in the 70S ribosome (By similarity). Binds to 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.
messages: The L3/L14/L24e cluster may contact the 16S rRNA in 2 intersubunit bridges (By similarity). Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e.

272569:RR RS18185
gene id: 272569:RR_RS18185
uniprot id: Q5UXV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS14330
gene id: 272569:RR_RS14330
uniprot id: Q5V015
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS07565
gene id: 272569:RR_RS07565
uniprot id: Q5V3V9
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

272569:RR RS16300
gene id: 272569:RR_RS16300
uniprot id: Q5UYY0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

272569:RR RS16290
gene id: 272569:RR_RS16290
uniprot id: Q5UYY1
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS04680
gene id: 272569:RR_RS04680
uniprot id: A0A4P8K1N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS18990
gene id: 272569:RR_RS18990
uniprot id: Q5UXE4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS16530
gene id: 272569:RR_RS16530
uniprot id: A0A4P8K162
names: Function
messages: Part of a potassium transport system.

272569:RR RS18550
gene id: 272569:RR_RS18550
uniprot id: Q5UXN2
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS04195
gene id: 272569:RR_RS04195
uniprot id: Q5V5T1
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS14065
gene id: 272569:RR_RS14065
uniprot id: Q5V060
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

272569:RR RS06515
gene id: 272569:RR_RS06515
uniprot id: Q5V4G9
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS04780
gene id: 272569:RR_RS04780
uniprot id: Q5V5G6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

272569:RR RS08175
gene id: 272569:RR_RS08175
uniprot id: Q5V3J0
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS04330
gene id: 272569:RR_RS04330
uniprot id: A0A4P8K0M6
uniprot id: P29199
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

272569:RR RS20595
gene id: 272569:RR_RS20595
uniprot id: Q5UWG5
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS18570
gene id: 272569:RR_RS18570
uniprot id: A0A4P8JZR2
uniprot id: Q5UXM8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell membrane
messages: Expressed constitutively throughout the growth phases, both in presence and absence of white light.
messages: Interacts with Sop1.
messages: Transduces signals from the phototaxis receptor sensory rhodopsin I (Sop1).

272569:RR RS17075
gene id: 272569:RR_RS17075
uniprot id: Q5UYH2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

272569:RR RS09195
gene id: 272569:RR_RS09195
uniprot id: A0A4P8JWG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

272569:RR RS15775
gene id: 272569:RR_RS15775
uniprot id: A0A4P8K0V2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

272569:RR RS04430
gene id: 272569:RR_RS04430
uniprot id: Q5V5N5
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 zinc ion.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

272569:RR RS03715
gene id: 272569:RR_RS03715
uniprot id: A0A4P8JW14
names: Similarity
messages: Belongs to the RutC family.

272569:RR RS05710
gene id: 272569:RR_RS05710
uniprot id: Q5V4Y1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS18995
gene id: 272569:RR_RS18995
uniprot id: Q5UXE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

272569:RR RS07460
gene id: 272569:RR_RS07460
uniprot id: A0A4P8JVL6
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS14315
gene id: 272569:RR_RS14315
uniprot id: Q5V018
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

272569:RR RS04170
gene id: 272569:RR_RS04170
uniprot id: A0A4P8K0K0
uniprot id: Q5V5T7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

272569:RR RS20940
gene id: 272569:RR_RS20940
uniprot id: Q5UW92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

272569:RR RS14935
gene id: 272569:RR_RS14935
uniprot id: A0A4P8JY92
uniprot id: Q5UZP9
names: Similarity
messages: Belongs to the SUI1 family.

272569:RR RS09475
gene id: 272569:RR_RS09475
uniprot id: A0A4P8JUA5
uniprot id: Q5V2S5
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

272569:RR RS08745
gene id: 272569:RR_RS08745
uniprot id: A0A4V1ELZ7
uniprot id: Q5V375
names: Similarity
messages: Belongs to the UPF0179 family.

272569:RR RS08145
gene id: 272569:RR_RS08145
uniprot id: Q5V3J6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

272569:RR RS18015
gene id: 272569:RR_RS18015
uniprot id: Q5UXZ0
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

272569:RR RS12095
gene id: 272569:RR_RS12095
uniprot id: A0A4P8K0B1
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

272569:RR RS11365
gene id: 272569:RR_RS11365
uniprot id: Q5V1P3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

272569:RR RS16105
gene id: 272569:RR_RS16105
uniprot id: Q5UZ19
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

272569:RR RS04935
gene id: 272569:RR_RS04935
uniprot id: A0A4P8K4T9
uniprot id: Q5V5D5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

272569:RR RS15025
gene id: 272569:RR_RS15025
uniprot id: Q5UZN0
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS18375
gene id: 272569:RR_RS18375
uniprot id: Q5UXR5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

272569:RR RS05050
gene id: 272569:RR_RS05050
uniprot id: Q5V5B4
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS17750
gene id: 272569:RR_RS17750
uniprot id: Q5UY41
names: Similarity
messages: In the N-terminal section; belongs to the ChdC family.

272569:RR RS14290
gene id: 272569:RR_RS14290
uniprot id: Q5V023
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal dihydroneopterin aldolase family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
messages: Homotetramer.

272569:RR RS02400
gene id: 272569:RR_RS02400
uniprot id: Q5V6V3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS03110
gene id: 272569:RR_RS03110
uniprot id: Q5V6F8
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

272569:RR RS18025
gene id: 272569:RR_RS18025
uniprot id: A0A4P8JYA2
uniprot id: Q5UXY8
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

272569:RR RS08070
gene id: 272569:RR_RS08070
uniprot id: A0A4P8JTM5
uniprot id: Q5V3L1
names: Caution
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
messages: Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS07900
gene id: 272569:RR_RS07900
uniprot id: A0A4P8JTK9
uniprot id: Q5V3P6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

272569:RR RS19235
gene id: 272569:RR_RS19235
uniprot id: A0A4P8K449
uniprot id: Q5UX95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

272569:RR RS15440
gene id: 272569:RR_RS15440
uniprot id: A0A4P8JYA6
uniprot id: Q5UZF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

272569:RR RS18170
gene id: 272569:RR_RS18170
uniprot id: Q5UXV8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

272569:RR RS20720
gene id: 272569:RR_RS20720
uniprot id: Q5UWD8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

272569:RR RS06780
gene id: 272569:RR_RS06780
uniprot id: A0A4P8JU25
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

272569:RR RS19635
gene id: 272569:RR_RS19635
uniprot id: A0A4P8JZ61
uniprot id: Q5UX13
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: May catalyze a purine salvage reaction, the substrate is unknown.

272569:RR RS05810
gene id: 272569:RR_RS05810
uniprot id: Q5V4W1
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

272569:RR RS14040
gene id: 272569:RR_RS14040
uniprot id: A0A4P8JXN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

272569:RR RS12345
gene id: 272569:RR_RS12345
uniprot id: Q5V146
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

272569:RR RS07425
gene id: 272569:RR_RS07425
uniprot id: Q5V3Y8
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

272569:RR RS07355
gene id: 272569:RR_RS07355
uniprot id: Q5V402
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS03100
gene id: 272569:RR_RS03100
uniprot id: A0A4P8JUQ3
uniprot id: Q5V6G0
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

272569:RR RS20750
gene id: 272569:RR_RS20750
uniprot id: Q5UWD2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

272569:RR RS04165
gene id: 272569:RR_RS04165
uniprot id: Q5V5T8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS07100
gene id: 272569:RR_RS07100
uniprot id: A0A4P8JU80
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS04155
gene id: 272569:RR_RS04155
uniprot id: Q5V5U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS20920
gene id: 272569:RR_RS20920
uniprot id: Q5UW97
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS15220
gene id: 272569:RR_RS15220
uniprot id: A0A4P8K0Q6
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS14830
gene id: 272569:RR_RS14830
uniprot id: Q5UZR7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

272569:RR RS18075
gene id: 272569:RR_RS18075
uniprot id: A0A4P8JZP9
uniprot id: Q5UXX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

272569:RR RS14285
gene id: 272569:RR_RS14285
uniprot id: Q5V024
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes the NAD-dependent oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Homodimer.

272569:RR RS02790
gene id: 272569:RR_RS02790
uniprot id: Q5V6M4
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS10370
gene id: 272569:RR_RS10370
uniprot id: Q5V292
names: Similarity
messages: Belongs to the DMRL synthase family.

272569:RR RS12920
gene id: 272569:RR_RS12920
uniprot id: Q5V0T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

272569:RR RS11585
gene id: 272569:RR_RS11585
uniprot id: A0A4P8JYV2
uniprot id: Q5V1K0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

272569:RR RS03690
gene id: 272569:RR_RS03690
uniprot id: A0A4P8JW77
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

272569:RR RS05100
gene id: 272569:RR_RS05100
uniprot id: A0A4P8K1U8
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS06770
gene id: 272569:RR_RS06770
uniprot id: Q5V4B8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS16615
gene id: 272569:RR_RS16615
uniprot id: A0A4P8JZ10
uniprot id: Q5UYR8
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

272569:RR RS02130
gene id: 272569:RR_RS02130
uniprot id: Q5V799
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.

272569:RR RS13360
gene id: 272569:RR_RS13360
uniprot id: Q5V0J9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS11135
gene id: 272569:RR_RS11135
uniprot id: A0A4P8JYM4
uniprot id: P14124
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit. Interacts with protein L18 and the 5S rRNA, and probably with tRNAs. Forms a bridge to the 30S subunit in the 70S ribosome (By similarity).
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of 5 proteins that mediates the attachment of the 5S rRNA onto the large ribosomal subunit, stabilizing the orientation of adjacent RNA domains. Forms part of the central protuberance. Modeling places the A and P site tRNAs in close proximity to this protein; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. In the 70S ribosome it is thought to contact protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

272569:RR RS10755
gene id: 272569:RR_RS10755
uniprot id: Q5V214
names: Miscellaneous
names: Subunit
messages: Component I catalyzes the formation of anthranilate using ammonia rather than glutamine, whereas component II provides glutamine amidotransferase activity.
messages: Tetramer of two components I and two components II.

272569:RR RS11105
gene id: 272569:RR_RS11105
uniprot id: A0A4P8JW67
uniprot id: P14123
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: Part of the 50S ribosomal subunit. Interacts with proteins L5 and L21e, and attaches the 5S rRNA to the 23S rRNA. Has been cross-linked to L21e.
messages: This is one of 5 proteins that mediate the attachment of the 5S rRNA onto the large ribosomal subunit, where it forms part of the central protuberance and stabilizes the orientation of adjacent RNA domains.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

272569:RR RS04160
gene id: 272569:RR_RS04160
uniprot id: Q5V5T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS04345
gene id: 272569:RR_RS04345
uniprot id: A0A4P8K4J1
uniprot id: P29202
names: PTM
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.
messages: The N-terminus is blocked.

272569:RR RS03730
gene id: 272569:RR_RS03730
uniprot id: A0A4P8JSX3
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS11630
gene id: 272569:RR_RS11630
uniprot id: Q5V1J2
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS15345
gene id: 272569:RR_RS15345
uniprot id: A0A4P8JX42
uniprot id: Q5UZG9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

272569:RR RS17650
gene id: 272569:RR_RS17650
uniprot id: A0A4V1EMG5
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).

272569:RR RS11755
gene id: 272569:RR_RS11755
uniprot id: A0A4P8JXJ9
uniprot id: Q5V1G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

272569:RR RS04855
gene id: 272569:RR_RS04855
uniprot id: Q5V5F2
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS14135
gene id: 272569:RR_RS14135
uniprot id: A0A4P8K028
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

272569:RR RS05405
gene id: 272569:RR_RS05405
uniprot id: Q5V544
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

272569:RR RS19315
gene id: 272569:RR_RS19315
uniprot id: Q5UX79
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS12820
gene id: 272569:RR_RS12820
uniprot id: A0A4P8JZE5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

272569:RR RS10485
gene id: 272569:RR_RS10485
uniprot id: Q5V269
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS12350
gene id: 272569:RR_RS12350
uniprot id: A0A4P8JZ65
uniprot id: Q5V145
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS14520
gene id: 272569:RR_RS14520
uniprot id: A0A4P8JXW0
uniprot id: P60617
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Part of the 50S ribosomal subunit. Weakly binds 5S rRNA. Probably binds the A and P site tRNAs.
messages: This is 1 of 5 proteins that mediate the attachment of the 5S rRNA onto the large ribosomal subunit, stabilizing the orientation of adjacent RNA domains. Modeling places the A and P site tRNAs in close proximity to this protein.

272569:RR RS10470
gene id: 272569:RR_RS10470
uniprot id: A0A4P8JW53
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS07015
gene id: 272569:RR_RS07015
uniprot id: Q5V468
names: Function
names: Similarity
messages: Belongs to the CoA-transferase III family.
messages: Involved in the methylaspartate cycle. Catalyzes the transfer of the CoA moiety from succinyl-CoA to mesaconate to generate mesaconyl-CoA (2-methylfumaryl-CoA) and succinate.

272569:RR RS04420
gene id: 272569:RR_RS04420
uniprot id: Q5V5N7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

272569:RR RS10045
gene id: 272569:RR_RS10045
uniprot id: Q5V2F5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS04130
gene id: 272569:RR_RS04130
uniprot id: A0A4P8JZ63
uniprot id: Q5V5U5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

272569:RR RS01535
gene id: 272569:RR_RS01535
uniprot id: Q5V6Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

272569:RR RS13835
gene id: 272569:RR_RS13835
uniprot id: Q5V0A6
names: Function
names: Subunit
messages: Interacts with chemotaxis (Che) proteins as well as flagella accessory (Fla) proteins.
messages: Involved in taxis signal transduction.

272569:RR RS14565
gene id: 272569:RR_RS14565
uniprot id: A0A4P8JYY4
uniprot id: Q5UZW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

272569:RR RS11995
gene id: 272569:RR_RS11995
uniprot id: Q5V1B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

272569:RR RS13635
gene id: 272569:RR_RS13635
uniprot id: Q5V0E5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS01655
gene id: 272569:RR_RS01655
uniprot id: Q5V7D3
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

272569:RR RS18700
gene id: 272569:RR_RS18700
uniprot id: A0A4V1EMI5
uniprot id: Q5UXK3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

272569:RR RS15450
gene id: 272569:RR_RS15450
uniprot id: A0A4P8K5H2
names: Function
messages: Part of a potassium transport system.

272569:RR RS04895
gene id: 272569:RR_RS04895
uniprot id: A0A4P8K0M9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

272569:RR RS16740
gene id: 272569:RR_RS16740
uniprot id: A0A4P8K2G4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
messages: Has ATPase and non-specific DNA-binding activities.

272569:RR RS08710
gene id: 272569:RR_RS08710
uniprot id: Q5V381
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

272569:RR RS03415
gene id: 272569:RR_RS03415
uniprot id: Q5V695
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

272569:RR RS08310
gene id: 272569:RR_RS08310
uniprot id: Q5V3G4
names: Similarity
messages: Belongs to the HypE family.

272569:RR RS11700
gene id: 272569:RR_RS11700
uniprot id: A0A4P8JYU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

272569:RR RS10475
gene id: 272569:RR_RS10475
uniprot id: Q5V271
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS12430
gene id: 272569:RR_RS12430
uniprot id: Q5V129
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS05510
gene id: 272569:RR_RS05510
uniprot id: Q5V522
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

272569:RR RS17865
gene id: 272569:RR_RS17865
uniprot id: A0A4P8JZL5
uniprot id: Q5UY20
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

272569:RR RS18970
gene id: 272569:RR_RS18970
uniprot id: Q5UXE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

272569:RR RS19475
gene id: 272569:RR_RS19475
uniprot id: Q5UX46
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

272569:RR RS16710
gene id: 272569:RR_RS16710
uniprot id: Q5UYP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

272569:RR RS11820
gene id: 272569:RR_RS11820
uniprot id: Q5V1F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

272569:RR RS21465
gene id: 272569:RR_RS21465
uniprot id: A0A4P8K1J0
uniprot id: P32410
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
messages: Part of the 50S ribosomal subunit. Interacts weakly with protein L4.

272569:RR RS03310
gene id: 272569:RR_RS03310
uniprot id: Q5V6B6
names: Similarity
messages: Belongs to the RutC family.

272569:RR RS08090
gene id: 272569:RR_RS08090
uniprot id: Q5V3K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS01845
gene id: 272569:RR_RS01845
uniprot id: Q5V750
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS15740
gene id: 272569:RR_RS15740
uniprot id: Q5UZ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

272569:RR RS14845
gene id: 272569:RR_RS14845
uniprot id: Q5UZR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

272569:RR RS07855
gene id: 272569:RR_RS07855
uniprot id: Q5V3Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

272569:RR RS13980
gene id: 272569:RR_RS13980
uniprot id: A0A4P8K006
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

272569:RR RS04300
gene id: 272569:RR_RS04300
uniprot id: A0A4P8K1H8
uniprot id: P10788
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

272569:RR RS07910
gene id: 272569:RR_RS07910
uniprot id: Q5V3P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

272569:RR RS07455
gene id: 272569:RR_RS07455
uniprot id: Q5V3Y1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

272569:RR RS11100
gene id: 272569:RR_RS11100
uniprot id: A0A4P8JXA0
uniprot id: P26815
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

272569:RR RS12490
gene id: 272569:RR_RS12490
uniprot id: A0A4P8JVK5
uniprot id: Q5V117
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

272569:RR RS02540
gene id: 272569:RR_RS02540
uniprot id: Q5V6S5
names: Similarity
messages: Belongs to the SCO1/2 family.

272569:RR RS13470
gene id: 272569:RR_RS13470
uniprot id: A0A4P8JZR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

272569:RR RS06840
gene id: 272569:RR_RS06840
uniprot id: Q5V4A4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS12520
gene id: 272569:RR_RS12520
uniprot id: Q5V111
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

272569:RR RS05040
gene id: 272569:RR_RS05040
uniprot id: Q5V5B6
names: Caution
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS15315
gene id: 272569:RR_RS15315
uniprot id: P00217
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2Fe2S plant-type ferredoxin family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

272569:RR RS17035
gene id: 272569:RR_RS17035
uniprot id: A0A4P8K651
uniprot id: Q5UYI1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

272569:RR RS21055
gene id: 272569:RR_RS21055
uniprot id: A0A4P8JVD5
uniprot id: Q5UW69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PhnC), two transmembrane proteins (PhnE) and a solute-binding protein (PhnD).

272569:RR RS09740
gene id: 272569:RR_RS09740
uniprot id: A0A4P8K2M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

272569:RR RS18845
gene id: 272569:RR_RS18845
uniprot id: A0A4P8JYS4
uniprot id: Q01100
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

272569:RR RS10195
gene id: 272569:RR_RS10195
uniprot id: Q5V2C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

272569:RR RS16905
gene id: 272569:RR_RS16905
uniprot id: A0A4P8K2J0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).

272569:RR RS12565
gene id: 272569:RR_RS12565
uniprot id: A0A4P8JWY0
uniprot id: Q5V103
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

272569:RR RS18820
gene id: 272569:RR_RS18820
uniprot id: A0A4P8K295
uniprot id: Q5UXH9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

272569:RR RS11985
gene id: 272569:RR_RS11985
uniprot id: Q5V1C0
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

272569:RR RS15600
gene id: 272569:RR_RS15600
uniprot id: Q5UZC0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

272569:RR RS11385
gene id: 272569:RR_RS11385
uniprot id: A0A4P8JWB0
uniprot id: Q5V1N9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

272569:RR RS08360
gene id: 272569:RR_RS08360
uniprot id: A0A4P8K203
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS15585
gene id: 272569:RR_RS15585
uniprot id: Q5UZC2
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS07645
gene id: 272569:RR_RS07645
uniprot id: Q5V3U4
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS16040
gene id: 272569:RR_RS16040
uniprot id: Q5UZ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

272569:RR RS12205
gene id: 272569:RR_RS12205
uniprot id: A0A4P8K3P3
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

272569:RR RS10705
gene id: 272569:RR_RS10705
uniprot id: Q5V223
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

272569:RR RS11415
gene id: 272569:RR_RS11415
uniprot id: Q5V1N3
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS07845
gene id: 272569:RR_RS07845
uniprot id: A0A4P8K1Q4
uniprot id: Q5V3Q5
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC), the main low-molecular-weight thiol compound instead of glutathione in halophilic archaea.

272569:RR RS11115
gene id: 272569:RR_RS11115
uniprot id: A0A4P8K381
uniprot id: P12736
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL32 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Interacts weakly with protein L15.

272569:RR RS20150
gene id: 272569:RR_RS20150
uniprot id: A0A4P8JRG8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

272569:RR RS09820
gene id: 272569:RR_RS09820
uniprot id: Q5V2K4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS06405
gene id: 272569:RR_RS06405
uniprot id: A0A4P8K104
uniprot id: Q5V4J1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS06420
gene id: 272569:RR_RS06420
uniprot id: A0A4P8JSV3
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

272569:RR RS02125
gene id: 272569:RR_RS02125
uniprot id: Q5V791
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

272569:RR RS12025
gene id: 272569:RR_RS12025
uniprot id: A0A4P8JWV2
uniprot id: Q5V1B3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS05530
gene id: 272569:RR_RS05530
uniprot id: A0A4P8K7W0
uniprot id: Q5V518
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

272569:RR RS08095
gene id: 272569:RR_RS08095
uniprot id: Q5V3K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS18560
gene id: 272569:RR_RS18560
uniprot id: A0A4P8K2D4
uniprot id: Q5UXN0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofG family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
messages: Consists of two subunits, CofG and CofH.
messages: The FO synthase complex consists of two subunits, CofG and CofH.

272569:RR RS04240
gene id: 272569:RR_RS04240
uniprot id: Q5V5S1
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS04395
gene id: 272569:RR_RS04395
uniprot id: Q5V5P2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

272569:RR RS04335
gene id: 272569:RR_RS04335
uniprot id: A0A4P8JZA0
uniprot id: P29200
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

272569:RR RS13375
gene id: 272569:RR_RS13375
uniprot id: A0A4P8K3T9
names: Similarity
messages: Belongs to the UPF0146 family.

272569:RR RS17475
gene id: 272569:RR_RS17475
uniprot id: Q5UY99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the halobacterial S-layer protein family.
messages: Cell membrane
messages: Membrane
messages: S-layer

272569:RR RS07125
gene id: 272569:RR_RS07125
uniprot id: Q5V446
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

272569:RR RS18460
gene id: 272569:RR_RS18460
uniprot id: A0A4P8K2B4
uniprot id: Q5UXP9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

272569:RR RS14570
gene id: 272569:RR_RS14570
uniprot id: A0A4P8JXX0
uniprot id: Q5UZW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

272569:RR RS16705
gene id: 272569:RR_RS16705
uniprot id: A0A4P8JYV3
uniprot id: Q5UYP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

272569:RR RS15750
gene id: 272569:RR_RS15750
uniprot id: A0A4P8JXB1
uniprot id: Q5UZ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

272569:RR RS08380
gene id: 272569:RR_RS08380
uniprot id: Q5V3E8
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS13825
gene id: 272569:RR_RS13825
uniprot id: A0A4P8JZX2
uniprot id: P21509
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

272569:RR RS11495
gene id: 272569:RR_RS11495
uniprot id: Q5V1L7
names: Similarity
messages: Belongs to the UPF0175 family.

272569:RR RS14550
gene id: 272569:RR_RS14550
uniprot id: A0A4P8K0B4
uniprot id: Q5UZX1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

272569:RR RS15715
gene id: 272569:RR_RS15715
uniprot id: Q5UZ97
names: Similarity
messages: Belongs to the P(II) protein family.

272569:RR RS10050
gene id: 272569:RR_RS10050
uniprot id: Q5V2F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

272569:RR RS03420
gene id: 272569:RR_RS03420
uniprot id: Q5V694
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

272569:RR RS20205
gene id: 272569:RR_RS20205
uniprot id: Q5UWP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS02805
gene id: 272569:RR_RS02805
uniprot id: Q5V6M1
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS07335
gene id: 272569:RR_RS07335
uniprot id: Q5V406
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS13670
gene id: 272569:RR_RS13670
uniprot id: Q5V0D8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

272569:RR RS05860
gene id: 272569:RR_RS05860
uniprot id: Q5V4V1
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS17880
gene id: 272569:RR_RS17880
uniprot id: Q5UY17
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS08085
gene id: 272569:RR_RS08085
uniprot id: Q5V3K8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS04215
gene id: 272569:RR_RS04215
uniprot id: Q5V5S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

272569:RR RS10205
gene id: 272569:RR_RS10205
uniprot id: Q5V2C2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

272569:RR RS10760
gene id: 272569:RR_RS10760
uniprot id: A0A4P8JZ51
uniprot id: Q5V213
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component I catalyzes the formation of anthranilate using ammonia rather than glutamine, whereas component II provides glutamine amidotransferase activity.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.
messages: Tetramer of two components I and two components II.

272569:RR RS14140
gene id: 272569:RR_RS14140
uniprot id: A0A4P8JYR7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

272569:RR RS04205
gene id: 272569:RR_RS04205
uniprot id: A0A4P8JZB1
uniprot id: Q5V5S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

272569:RR RS15630
gene id: 272569:RR_RS15630
uniprot id: A0A4P8K1X8
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS04900
gene id: 272569:RR_RS04900
uniprot id: Q5V5E2
names: Function
names: Similarity
messages: Belongs to the Tfx family.
messages: Putative transcriptional regulator.

272569:RR RS14480
gene id: 272569:RR_RS14480
uniprot id: Q5UZY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS14015
gene id: 272569:RR_RS14015
uniprot id: A0A4P8JWC0
uniprot id: Q5V070
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

272569:RR RS07040
gene id: 272569:RR_RS07040
uniprot id: Q5V463
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.
messages: Divalent cations such as magnesium or manganese.
messages: Involved in the methylaspartate cycle. Catalyzes the reversible cleavage of beta-methylmalyl-CoA to propionyl-CoA and glyoxylate, as well as the reversible cleavage of (S)-malyl-CoA to acetyl-CoA and glyoxylate. In addition, it has a small malyl-CoA thioesterase activity. It can also catalyzes the cleavage of (S)-citramalyl-CoA to acetyl-CoA and pyruvate.

272569:RR RS20210
gene id: 272569:RR_RS20210
uniprot id: Q5UWP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS11745
gene id: 272569:RR_RS11745
uniprot id: A0A4P8JZL1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

272569:RR RS11650
gene id: 272569:RR_RS11650
uniprot id: A0A4P8JYU1
uniprot id: Q5V1I9
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

272569:RR RS13975
gene id: 272569:RR_RS13975
uniprot id: Q5V078
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS03865
gene id: 272569:RR_RS03865
uniprot id: Q5V604
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

272569:RR RS04790
gene id: 272569:RR_RS04790
uniprot id: Q5V5G4
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

272569:RR RS19140
gene id: 272569:RR_RS19140
uniprot id: Q5UXB4
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

272569:RR RS05440
gene id: 272569:RR_RS05440
uniprot id: Q5V537
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

272569:RR RS06485
gene id: 272569:RR_RS06485
uniprot id: Q5V4H5
names: Similarity
messages: Belongs to the PEPCase type 1 family.

272569:RR RS13650
gene id: 272569:RR_RS13650
uniprot id: Q5V0E2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS19300
gene id: 272569:RR_RS19300
uniprot id: Q5UX82
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

272569:RR RS04800
gene id: 272569:RR_RS04800
uniprot id: A0A4P8JZK7
uniprot id: Q5V5G2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

272569:RR RS18220
gene id: 272569:RR_RS18220
uniprot id: A0A4P8JZS8
uniprot id: Q5UXU6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

272569:RR RS00815
gene id: 272569:RR_RS00815
uniprot id: Q5V7X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

272569:RR RS07720
gene id: 272569:RR_RS07720
uniprot id: A0A4P8JWZ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS10280
gene id: 272569:RR_RS10280
uniprot id: A0A4P8JWX4
uniprot id: P15825
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Has been called L10e and L10E in this organism; in this case 'e/E' is for E.coli-like, not eukaryotic-type protein.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion (Probable).
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

272569:RR RS01315
gene id: 272569:RR_RS01315
uniprot id: A0A4P8JS79
uniprot id: Q5V7E8
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

272569:RR RS04485
gene id: 272569:RR_RS04485
uniprot id: A0A4P8JZC4
uniprot id: P12743
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Interacts with protein L15e. Probably part of the RNase P complex.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.
messages: Was originally thought to be a protein from the small subunit of the ribosome.

272569:RR RS18945
gene id: 272569:RR_RS18945
uniprot id: Q5UXF4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS12385
gene id: 272569:RR_RS12385
uniprot id: A0A4P8JX11
uniprot id: Q5V138
names: Similarity
messages: Belongs to the TrpC family.

272569:RR RS05250
gene id: 272569:RR_RS05250
uniprot id: A0A4P8K1X7
uniprot id: Q5V574
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

272569:RR RS10585
gene id: 272569:RR_RS10585
uniprot id: Q5V249
names: Similarity
messages: Belongs to the glycosyl hydrolase 68 family.

272569:RR RS04090
gene id: 272569:RR_RS04090
uniprot id: A0A4P8K4F1
uniprot id: Q5V5V3
names: Function
names: Induction
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Expressed constitutively throughout the growth phases, both in presence and absence of white light.
messages: Mediates the photorepellent response.
messages: Membrane
messages: The covalent binding of retinal to the apoprotein, bacterioopsin, generates bacteriorhodopsin.

272569:RR RS20670
gene id: 272569:RR_RS20670
uniprot id: Q5UWE9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS04495
gene id: 272569:RR_RS04495
uniprot id: A0A4P8K4L7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

272569:RR RS18270
gene id: 272569:RR_RS18270
uniprot id: A0A4P8JZT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecD.

272569:RR RS11505
gene id: 272569:RR_RS11505
uniprot id: Q5V1L5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

272569:RR RS11140
gene id: 272569:RR_RS11140
uniprot id: A0A4P8JZB0
uniprot id: P22510
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

272569:RR RS04295
gene id: 272569:RR_RS04295
uniprot id: A0A4P8K332
uniprot id: Q00862
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

272569:RR RS15955
gene id: 272569:RR_RS15955
uniprot id: Q5UZ51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS20560
gene id: 272569:RR_RS20560
uniprot id: A0A4P8JV49
uniprot id: Q5UWH2
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: The active site is a redox-active disulfide bond.

272569:RR RS03705
gene id: 272569:RR_RS03705
uniprot id: Q5V638
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

272569:RR RS19745
gene id: 272569:RR_RS19745
uniprot id: Q5UWZ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

272569:RR RS15295
gene id: 272569:RR_RS15295
uniprot id: Q5UZH8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

272569:RR RS02825
gene id: 272569:RR_RS02825
uniprot id: A0A4P8JWG9
uniprot id: Q75ZQ5
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

272569:RR RS10365
gene id: 272569:RR_RS10365
uniprot id: A0A4P8JW36
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS09835
gene id: 272569:RR_RS09835
uniprot id: Q5V2K1
names: Similarity
messages: Belongs to the AOR/FOR family.

272569:RR RS18050
gene id: 272569:RR_RS18050
uniprot id: A0A4P8JZH7
uniprot id: Q5UXY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

272569:RR RS08030
gene id: 272569:RR_RS08030
uniprot id: Q5V3L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS15065
gene id: 272569:RR_RS15065
uniprot id: A0A4P8JY46
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

272569:RR RS15225
gene id: 272569:RR_RS15225
uniprot id: Q5UZJ1
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

272569:RR RS18250
gene id: 272569:RR_RS18250
uniprot id: A0A4P8JZL2
uniprot id: Q5UXU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

272569:RR RS16195
gene id: 272569:RR_RS16195
uniprot id: Q5UZ01
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.

272569:RR RS15015
gene id: 272569:RR_RS15015
uniprot id: Q5UZN2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS03725
gene id: 272569:RR_RS03725
uniprot id: A0A4P8JU62
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS18440
gene id: 272569:RR_RS18440
uniprot id: A0A4P8JZW4
uniprot id: Q5UXQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

272569:RR RS11975
gene id: 272569:RR_RS11975
uniprot id: Q5V1C2
names: Similarity
messages: Belongs to the arginase family.

272569:RR RS05965
gene id: 272569:RR_RS05965
uniprot id: Q5V4T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

272569:RR RS14035
gene id: 272569:RR_RS14035
uniprot id: Q5V066
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.

272569:RR RS10240
gene id: 272569:RR_RS10240
uniprot id: Q5V2B6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS16395
gene id: 272569:RR_RS16395
uniprot id: A0A4P8JYQ2
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS19690
gene id: 272569:RR_RS19690
uniprot id: Q5UX02
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS16650
gene id: 272569:RR_RS16650
uniprot id: Q5UYR1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

272569:RR RS11200
gene id: 272569:RR_RS11200
uniprot id: A0A4P8JXB6
uniprot id: P20279
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e. Interacts weakly with protein L13.

272569:RR RS08035
gene id: 272569:RR_RS08035
uniprot id: Q5V3L8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS20115
gene id: 272569:RR_RS20115
uniprot id: Q5UWR5
names: Similarity
messages: Belongs to the UPF0175 family.

272569:RR RS08825
gene id: 272569:RR_RS08825
uniprot id: Q5V359
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

272569:RR RS11815
gene id: 272569:RR_RS11815
uniprot id: Q5V1F5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS18645
gene id: 272569:RR_RS18645
uniprot id: Q5UXL4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS07700
gene id: 272569:RR_RS07700
uniprot id: Q5V3T3
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Belongs to the isochorismate synthase family.

272569:RR RS18105
gene id: 272569:RR_RS18105
uniprot id: Q5UXX1
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS10335
gene id: 272569:RR_RS10335
uniprot id: A0A4P8JY89
uniprot id: P05762
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

272569:RR RS11860
gene id: 272569:RR_RS11860
uniprot id: A0A4P8JVG2
uniprot id: Q5V1E6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

272569:RR RS04320
gene id: 272569:RR_RS04320
uniprot id: A0A4P8K7F1
uniprot id: P29198
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: Part of the 50S ribosomal subunit. Interacts weakly with proteins L3 and L6.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit (By similarity). Binds to 23S rRNA.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

272569:RR RS07075
gene id: 272569:RR_RS07075
uniprot id: A0A4P8JXD8
uniprot id: Q5V456
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

272569:RR RS04305
gene id: 272569:RR_RS04305
uniprot id: A0A4P8K0E3
uniprot id: Q00813
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.

272569:RR RS07655
gene id: 272569:RR_RS07655
uniprot id: Q5V3U2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS08575
gene id: 272569:RR_RS08575
uniprot id: A0A4P8JVC7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS13915
gene id: 272569:RR_RS13915
uniprot id: Q5V090
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS06350
gene id: 272569:RR_RS06350
uniprot id: Q5V4K1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

272569:RR RS18290
gene id: 272569:RR_RS18290
uniprot id: Q5UXT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

272569:RR RS12335
gene id: 272569:RR_RS12335
uniprot id: Q5V148
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

272569:RR RS13405
gene id: 272569:RR_RS13405
uniprot id: A0A4P8JW09
uniprot id: Q5V0J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

272569:RR RS06985
gene id: 272569:RR_RS06985
uniprot id: A0A4P8JU63
uniprot id: Q5V474
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

272569:RR RS13030
gene id: 272569:RR_RS13030
uniprot id: A0A4P8JZL4
uniprot id: Q5V0R5
names: Function
names: Induction
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Expressed constitutively throughout the growth phases, both in presence and absence of white light.
messages: Light-driven proton pump.
messages: Membrane
messages: The covalent binding of retinal to the apoprotein, bacterioopsin, generates bacteriorhodopsin.

272569:RR RS13380
gene id: 272569:RR_RS13380
uniprot id: Q5V0J6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

272569:RR RS12005
gene id: 272569:RR_RS12005
uniprot id: A0A4P8JWM8
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

272569:RR RS19685
gene id: 272569:RR_RS19685
uniprot id: Q5UX03
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS13680
gene id: 272569:RR_RS13680
uniprot id: Q5V0D5
names: Similarity
messages: Belongs to the selenium-binding protein family.

272569:RR RS09480
gene id: 272569:RR_RS09480
uniprot id: Q5V2S4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS17335
gene id: 272569:RR_RS17335
uniprot id: A0A4P8K693
uniprot id: Q5UYC8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

272569:RR RS05200
gene id: 272569:RR_RS05200
uniprot id: A0A4P8K1W6
uniprot id: Q5V584
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

272569:RR RS04650
gene id: 272569:RR_RS04650
uniprot id: Q5V5J2
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

272569:RR RS06340
gene id: 272569:RR_RS06340
uniprot id: A0A4P8JSU9
uniprot id: Q5V4K3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

272569:RR RS19220
gene id: 272569:RR_RS19220
uniprot id: Q5UX98
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS12800
gene id: 272569:RR_RS12800
uniprot id: A0A4P8JX81
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

272569:RR RS19115
gene id: 272569:RR_RS19115
uniprot id: A0A4P8K080
uniprot id: Q5UXB9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

272569:RR RS12210
gene id: 272569:RR_RS12210
uniprot id: Q5V176
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

272569:RR RS03795
gene id: 272569:RR_RS03795
uniprot id: Q5V620
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

272569:RR RS09830
gene id: 272569:RR_RS09830
uniprot id: Q5V2K2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

272569:RR RS04825
gene id: 272569:RR_RS04825
uniprot id: A0A4P8K330
uniprot id: Q5V5F7
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

272569:RR RS15460
gene id: 272569:RR_RS15460
uniprot id: A0A4P8JYG6
uniprot id: Q5UZE6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

272569:RR RS16425
gene id: 272569:RR_RS16425
uniprot id: A0A4P8JYX3
uniprot id: Q5UYV8
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

272569:RR RS13190
gene id: 272569:RR_RS13190
uniprot id: A0A4P8JZP0
uniprot id: P60618
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Part of the 50S ribosomal subunit. Interacts with protein L7Ae and weakly with L44e.

272569:RR RS04440
gene id: 272569:RR_RS04440
uniprot id: Q5V5N3
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

272569:RR RS02210
gene id: 272569:RR_RS02210
uniprot id: A0A4P8JUU2
uniprot id: Q5V7B0
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

272569:RR RS07005
gene id: 272569:RR_RS07005
uniprot id: A0A4P8JUL6
uniprot id: Q5V470
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS17130
gene id: 272569:RR_RS17130
uniprot id: Q5UYG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

272569:RR RS05930
gene id: 272569:RR_RS05930
uniprot id: Q5V4T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

272569:RR RS06175
gene id: 272569:RR_RS06175
uniprot id: Q5V4N8
names: Similarity
messages: Belongs to the peptidase C56 family.

272569:RR RS12610
gene id: 272569:RR_RS12610
uniprot id: A0A4P8JZA7
uniprot id: Q5V0Z6
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

272569:RR RS03685
gene id: 272569:RR_RS03685
uniprot id: A0A4P8JSP4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

272569:RR RS14260
gene id: 272569:RR_RS14260
uniprot id: Q5V028
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

272569:RR RS09215
gene id: 272569:RR_RS09215
uniprot id: A0A4V1EM06
uniprot id: Q5V2X8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

272569:RR RS04085
gene id: 272569:RR_RS04085
uniprot id: A0A4P8K5M3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

272569:RR RS06825
gene id: 272569:RR_RS06825
uniprot id: A0A4P8JVB0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

272569:RR RS06385
gene id: 272569:RR_RS06385
uniprot id: Q5V4J4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.

272569:RR RS10150
gene id: 272569:RR_RS10150
uniprot id: A0A4P8JYW0
uniprot id: Q5V2D3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

272569:RR RS13540
gene id: 272569:RR_RS13540
uniprot id: Q5V0G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

272569:RR RS04290
gene id: 272569:RR_RS04290
uniprot id: A0A4P8K4I3
uniprot id: Q00861
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

272569:RR RS15900
gene id: 272569:RR_RS15900
uniprot id: Q5UZ62
names: Similarity
messages: Belongs to the aspartokinase family.

272569:RR RS07400
gene id: 272569:RR_RS07400
uniprot id: Q5V3Z3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

272569:RR RS03495
gene id: 272569:RR_RS03495
uniprot id: Q5V679
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

272569:RR RS17555
gene id: 272569:RR_RS17555
uniprot id: Q5UY81
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS05560
gene id: 272569:RR_RS05560
uniprot id: Q5V512
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

272569:RR RS18090
gene id: 272569:RR_RS18090
uniprot id: A0A4P8K353
uniprot id: Q5UXX4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS12590
gene id: 272569:RR_RS12590
uniprot id: Q5V0Z9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

272569:RR RS03220
gene id: 272569:RR_RS03220
uniprot id: Q5V6D5
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS11465
gene id: 272569:RR_RS11465
uniprot id: Q5V1M3
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

272569:RR RS18565
gene id: 272569:RR_RS18565
uniprot id: A0A4P8K0U7
uniprot id: Q5UXM9
names: Function
names: Induction
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Expressed constitutively throughout the growth phases, both in presence and absence of white light.
messages: Interacts with Htr1.
messages: Membrane
messages: Photoattractant rhodopsin.
messages: The covalent binding of retinal to the apoprotein, bacterioopsin, generates bacteriorhodopsin.

272569:RR RS09560
gene id: 272569:RR_RS09560
uniprot id: Q5V2Q9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

272569:RR RS18495
gene id: 272569:RR_RS18495
uniprot id: Q5UXP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ModE family.
messages: Membrane

272569:RR RS10700
gene id: 272569:RR_RS10700
uniprot id: Q5V224
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

272569:RR RS17160
gene id: 272569:RR_RS17160
uniprot id: A0A4V1EMF6
uniprot id: Q5UYF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal long subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity).
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homodimer.

272569:RR RS03835
gene id: 272569:RR_RS03835
uniprot id: Q5V611
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS04150
gene id: 272569:RR_RS04150
uniprot id: Q5V5U1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

272569:RR RS03760
gene id: 272569:RR_RS03760
uniprot id: Q5V627
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS14310
gene id: 272569:RR_RS14310
uniprot id: Q5V019
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

272569:RR RS15135
gene id: 272569:RR_RS15135
uniprot id: A0A4P8K5B9
uniprot id: Q06125
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Part of the 30S ribosomal subunit.

272569:RR RS10995
gene id: 272569:RR_RS10995
uniprot id: Q5V1W4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272569:RR RS04490
gene id: 272569:RR_RS04490
uniprot id: A0A4P8K2X9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

272569:RR RS15515
gene id: 272569:RR_RS15515
uniprot id: A0A4P8JYH4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

272569:RR RS20170
gene id: 272569:RR_RS20170
uniprot id: Q5UWQ5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

272569:RR RS10395
gene id: 272569:RR_RS10395
uniprot id: A0A4P8JWZ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272569:RR RS12695
gene id: 272569:RR_RS12695
uniprot id: Q5V0Y0
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

272569:RR RS12965
gene id: 272569:RR_RS12965
uniprot id: A0A4P8JXA9
uniprot id: Q5V0S8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

272569:RR RS00860
gene id: 272569:RR_RS00860
uniprot id: Q5V7G9
names: Subcellular Location Annotation
messages: Membrane

272569:RR RS08185
gene id: 272569:RR_RS08185
uniprot id: A0A4P8JX80
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

272569:RR RS04375
gene id: 272569:RR_RS04375
uniprot id: Q5V5P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

272569:RR RS10180
gene id: 272569:RR_RS10180
uniprot id: A0A4P8K2T3
uniprot id: Q5V2C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

272569:RR RS11840
gene id: 272569:RR_RS11840
uniprot id: Q5V1F0
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

272569:RR RS15305
gene id: 272569:RR_RS15305
uniprot id: A0A4V1EMC1
uniprot id: Q5UZH6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

272569:RR RS04640
gene id: 272569:RR_RS04640
uniprot id: Q5V5J5
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

272569:RR RS02215
gene id: 272569:RR_RS02215
uniprot id: Q5V7A9
names: Similarity
messages: Belongs to the DNA polymerase type-B family.